Fujita Naoya 藤田直也

… Alternative Names

FUJITA Naoya 藤田直也

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Researcher Number	20280951
Other IDs	https://orcid.org/0000-0002-9631-9264
Affiliation (Current)	2025: 公益財団法人がん研究会, がん化学療法センター, 所長
Affiliation (based on the past Project Information) *help	2014 – 2024: 公益財団法人がん研究会, がん化学療法センター, 所長 2012 – 2014: 公益財団法人がん研究会, その他部局等, その他 2013: 公益財団法人がん研究会, がん化学療法センター, 副所長 2011 – 2012: 公益財団法人がん研究会, がん化学療法センター・基礎研究部, 部長 2011 – 2012: 公益財団法人がん研究会, がん化学療法センター基礎研究部, 部長 … More 2010: 財団法人癌研究会, 癌化学療法センター基礎研究部, 部長 2009 – 2010: Japanese Foundation For Cancer Research, 癌化学療法センター基礎研究部, 部長 2008: Japanese Foundation For Cancer Research, 癌化学療法センター・基礎研究部, 部長 2008: Japanese Foundation For Cancer Research, 癌化学療法センター基礎研究部, 部長 2007: Japanese Foundation For Cancer Research, Cancer Chemotherapy Center, Division of Experimental Chemotherapy, Chief 2006: (財)癌研究会, 癌化学療法センター基礎研究部, 部長 2004 – 2005: 東京大学, 分子細胞生物学研究所, 助教授 1996 – 2003: 東京大学, 分子細胞生物学研究所, 助手 1997 – 1998: 東京大学, 分生研, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological Sciences / Biological pharmacy / Complex systems / Tumor therapeutics / Clinical oncology / Basic Section 50010:Tumor biology-related / Biological Sciences Except Principal Investigator Tumor therapeutics / Tumor diagnostics / Biological Sciences
Keywords	Principal Investigator 癌 / 生体分子 / 分子標的治療 / 血小板 / がん転移 / 血小板凝集 / Aggrus / 骨芽細胞 / 破骨細胞 / 骨転移 … More / 再生医療 / 臨床 / 遺伝子 / 細胞・組織 / 転移 / 血管内皮細胞 / 数理科学 / CD9 / Podoplanin / がん / 阻害剤 / 糖鎖 / 抗がん剤 / 生存シグナル / PDK1 / Akt / AKT / メラノーマ / 乳癌 / ポドプラニン / 数理モデル / 計算機科学 / 病理学 / 融合遺伝子 / 薬剤反応性 / 0-glycan / Tumor cells / Pulmonary metastasis / Tumor metastasis / Platelet aggregation / Podonlanin / がん細胞 / 肺転移 / c-Met / MET / EGFR-TKI / ALK / EGFR / 併用療法 / がん化学療法 / Pim / シグナル / p27^<Kip1> / 結晶構造解析 / Pimキナーゼ / 細胞死 / 微小環境 / Merm1 / がん微小環境 / 体内時計 / podoplanin / シグナル伝達 / CKIP-1 / Aki1 / 結合分子 / がん治療 / 肺癌 / モノクローナル抗体 / 14-3-3蛋白質 / p27Kip1 / 抗癌剤 / MAPK / MEK / WEE1Hu / 破骨細胞分化因子 / プロモーター解析 / RANKL / TGF-β / 蛋白分解 / HSP90 / カスパーゼ / アポトーシス / bFGF / IL-1 / 血管皮細胞 / 塩基性FGF … More Except Principal Investigator アポトーシス / Driver oncogene / がん / 細胞死 / 過剰活性化 / チロシンキナーゼ / 相互排他性 / がん遺伝子 / 肺腺がん / 分子標的治療 / プロテオミクス解析 / 肺がん / 大腸がん / 薬剤耐性機序 / リン酸化プロテオーム解析 / ゲノム医学 / リンパ管新生 / 血管新生 / 転移 / がん浸潤 / がん微小環境 / ゲノム科学 / 生体イメージング / 生体材料 / シグナル伝達 / 微小環境 / アポトーシスエンドヌクレアーゼ / トポイソメラーゼIIα / エンドトキシンLPS / Fas / myc関連遺伝子 / CED-3 family proteases / ICE / リンパ腫 / Pim-1キナーゼ / LPS / アポトーシス耐性 / カスパーゼ3様プロテアーゼ / アポトーシスシグナル / FasL / Bax / 制がん剤 / アデノウイルスE1A / Myc / 癌移転 / 癌転移 / 耐性克服 / 分子標的 / 耐性遺伝子 / 耐性タンパク / 抗癌剤耐性 / P-糖タンパク Less

Integrated analysis and regulation of cellular diversityPrincipal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Japanese Foundation for Cancer Research
Tumor growth and metastasis via podoplanin-dependent platelet aggregationPrincipal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Japanese Foundation for Cancer Research
Integrated analysis and regulation of cellular diversityArea Organizer
- Area Organizer
  
  藤田直也
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Integrated analysis and regulation of cellular diversityPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Japanese Foundation for Cancer Research
Integrated analysis and regulation of cellular diversity for disease treatmentPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Japanese Foundation for Cancer Research
Discovery of drug resistant mechnism by kinome analysis using patient derived cultured cells
- Principal Investigator
  
  Tomonaga Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Molecular analysis of acquired resistance to targeted therapies and search for overcoming drugsPrincipal Investigator
- Principal Investigator
  
  Fujita Naoya
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Mutual exclusiveness of driver oncogenes
- Principal Investigator
  
  KATAYAMA Ryohei
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Molecular analysis of platelet-mediated tumor suppression and development of the anti-tumor therapyPrincipal Investigator
- Principal Investigator
  
  Fujita Naoya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Molecular analysis of EGFR-TKI resistance and development of overcoming drugsPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation for Cancer Research
Integrative Research on Cancer Microenvironment Network
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Molecular analysis of metastasis-related tumor microenvironment and development of new anti-metastatic therapyPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation for Cancer Research
Generation of Pim kinase inhibitors based on structural and post-transcriptional analysisPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Clinical oncology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
足場タンパク質を標的にしたAKT活性制御法開発とがん治療への応用Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Suppression of platelet aggregation mediated by metastasis-promoting Aggrus proteinPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
Aktを介したサーカディアンリズムの制御Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
PDK1-AKT経路の新たな活性制御機構の解明とがん治療への応用Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Molecular analysis of novel platelet aggregation-inducing factor AggrusPrincipal Investigator
- Principal Investigator
  
  FUJITA Naoya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
癌転移に関わる新規血小板凝集誘導因子Aggrusの血小板凝集誘導機構の解析Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
生存シグナル伝達を阻害する新規物質の探索Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
骨血管内皮細胞を介した破骨細胞形成誘導機構の解析Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
生存シグナル伝達に関わるAKTのカスバーゼによる分解とその活性調節機構の解析Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
骨血管内皮細胞による骨吸収誘導機構Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
癌細胞の骨転移形成過程における血管内皮細胞の役割Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
アポトーシス機構の解析とその発がん、制がん研究への応用
- Principal Investigator
  
  口野嘉幸
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
癌細胞の骨転移形成に関わる破骨細胞形成因子とその作用機序Principal Investigator
- Principal Investigator
  
  藤田直也
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
がん細胞の薬剤感受性と抵抗性の分子機構とその制御
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo

[Book] がん微小環境に１細胞レベルで挑む2021
- Author(s)
  藤田　直也
- Total Pages
  220
- Publisher
  羊土社
- ISBN
  9784758103961
- Data Source
  KAKENHI-PLANNED-17H06327
[Book] がん微小環境に１細胞レベルで挑む2021
- Author(s)
  藤田　直也
- Total Pages
  220
- Publisher
  羊土社
- ISBN
  9784758103961
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Book] がんの分子標的と治療薬事典2010
- Author(s)
  藤田直也
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20390029
[Book] がん分子標的治療研究実践マニュアル2009
- Author(s)
  片山量平、藤田直也
- Publisher
  金芳堂
- Data Source
  KAKENHI-PROJECT-20390029
[Book] がんの分子標的治療2008
- Author(s)
  藤田直也
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20390029
[Book] 構造生物学-ポストゲノム時代のタンパク質研究-2007
- Author(s)
  藤田直也
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390020
[Book] 構造生物学-ポストゲノム時代のタンパク質研究-2007
- Author(s)
  藤田直也
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-18015008
[Journal Article] Soluble PD-L1 works as a decoy in lung cancer immunotherapy via alternative polyadenylation2022
- Author(s)
  Sagawa Ray、Sakata Seiji、Gong Bo、Seto Yosuke、Takemoto Ai、Takagi Satoshi、Ninomiya Hironori、Yanagitani Noriko、Nakao Masayuki、Mun Mingyon、Uchibori Ken、Nishio Makoto、Miyazaki Yasunari、Shiraishi Yuichi、Ogawa Seishi、Kataoka Keisuke、Fujita Naoya、Takeuchi Kengo、Katayama Ryohei
- Journal Title
  
  JCI Insight
  
  Volume: 7 Issue: 1 Pages: 1-19
- DOI
  10.1172/jci.insight.153323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K16370, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K07399
[Journal Article] Targeting Podoplanin for the Treatment of Osteosarcoma2022
- Author(s)
  Takemoto Ai、Takagi Satoshi、Ukaji Takao、Gyobu Nobuhiko、Kakino Mamoru、Takami Miho、Kobayashi Asami、Lebel Marie、Kawaguchi Tokuichi、Sugawara Minoru、Tsuji-Takayama Kazue、Ichihara Kenji、Funauchi Yuki、Ae Keisuke、Matsumoto Seiichi、Sugiura Yoshiya、Takeuchi Kengo、Noda Tetsuo、Katayama Ryohei、Fujita Naoya
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 28 Issue: 12 Pages: 2633-2645
- DOI
  10.1158/1078-0432.ccr-21-4509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24167
[Journal Article] GSK3 inhibition circumvents and overcomes acquired lorlatinib resistance in ALK-rearranged non-small-cell lung cancer2022
- Author(s)
  Shimizu Yuki、Okada Koutaroh、Adachi Jun、Abe Yuichi、Narumi Ryohei、Uchibori Ken、Yanagitani Noriko、Koike Sumie、Takagi Satoshi、Nishio Makoto、Fujita Naoya、Katayama Ryohei
- Journal Title
  
  npj Precision Oncology
  
  Volume: 6 Issue: 1 Pages: 16-16
- DOI
  10.1038/s41698-022-00260-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K07333, KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-23K20389
[Journal Article] Monitoring epidermal growth factor receptor C797S mutation in Japanese non?small cell lung cancer patients with serial cell‐free DNA evaluation using digital droplet PCR2021
- Author(s)
  Ariyasu Ryo、Uchibori Ken、Sasaki Takaaki、Tsukahara Mika、Kiyotani Kazuma、Yoshida Ryohei、Ono Yusuke、Kitazono Satoru、Ninomiya Hironori、Ishikawa Yuichi、Mizukami Yusuke、Yanagitani Noriko、Fujita Naoya、Nishio Makoto、Katayama Ryohei
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 6 Pages: 2371-2380
- DOI
  10.1111/cas.14879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03446, KAKENHI-PROJECT-18K15936, KAKENHI-PROJECT-20K21554, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K07671
[Journal Article] Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity2021
- Author(s)
  Yoshizawa Takahiro、Uchibori Ken、Araki Mitsugu、Matsumoto Shigeyuki、Ma Biao、Kanada Ryo、Seto Yosuke、Oh-hara Tomoko、Koike Sumie、Ariyasu Ryo、Kitazono Satoru、Ninomiya Hironori、Takeuchi Kengo、Yanagitani Noriko、Takagi Satoshi、Kishi Kazuma、Fujita Naoya、Okuno Yasushi、Nishio Makoto、Katayama Ryohei
- Journal Title
  
  npj Precision Oncology
  
  Volume: 5 Issue: 1 Pages: 32-32
- DOI
  10.1038/s41698-021-00170-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22572, KAKENHI-PROJECT-18K15936, KAKENHI-PROJECT-18K06594, KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K16370, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03524
[Journal Article] Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis2021
- Author(s)
  Takagi Satoshi、Sasaki Yuki、Koike Sumie、Takemoto Ai、Seto Yosuke、Haraguchi Mizuki、Ukaji Takao、Kawaguchi Tokuichi、Sugawara Minoru、Saito Masanori、Funauchi Yuki、Ae Keisuke、Matsumoto Seiichi、Fujita Naoya、Katayama Ryohei
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 36 Pages: 5548-5558
- DOI
  10.1038/s41388-021-01956-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-20K16370, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03524, KAKENHI-ORGANIZER-17H06324
[Journal Article] Novel knock-in mouse model for the evaluation of the therapeutic efficacy and toxicity of human podoplanin-targeting agents.2021
- Author(s)
  Ukaji T, Takemoto A, Shibata H, Kakino M, Takagi S, Katayama R, Fujita N
- Journal Title
  
  Cancer Science
  
  Volume: In press Issue: 6 Pages: 2299-2313
- DOI
  10.1111/cas.14891
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07216, KAKENHI-PROJECT-19K22572, KAKENHI-PLANNED-17H06327
[Journal Article] Gilteritinib overcomes lorlatinib resistance in ALK-rearranged cancer2021
- Author(s)
  Mizuta Hayato、Okada Koutaroh、Araki Mitsugu、Adachi Jun、Takemoto Ai、Kutkowska Justyna、Maruyama Kohei、Friboulet Luc、Katayama Kazuhiro、Ma Biao、Sasakura Yoko、Sagae Yukari、Kukimoto-Niino Mutsuko、Shirouzu Mikako、Takagi Satoshi、Simizu Siro、Nishio Makoto、Okuno Yasushi、Fujita Naoya、Katayama Ryohei, et al
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1261-1261
- DOI
  10.1038/s41467-021-21396-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-18K06137, KAKENHI-PROJECT-19K22572, KAKENHI-PROJECT-18K06594, KAKENHI-ORGANIZER-17H06324
[Journal Article] Efficacy of EGFR tyrosine kinase inhibitors in patients having EGFR-activating mutations with or without BIM polymorphisms2020
- Author(s)
  Ariyasu Ryo、Yanagitani Noriko、Tadokoro Kenichi、Yamaguchi Toshikazu、Uchibori Ken、Kitazono Satoru、Fujita Naoya、Katayama Ryohei、Nishio Makoto
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: 86 Issue: 4 Pages: 517-525
- DOI
  10.1007/s00280-020-04136-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21554, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03524
[Journal Article] Drug resistance mechanisms in Japanese anaplastic lymphoma kinase‐positive non?small cell lung cancer and the clinical responses based on the resistant mechanisms2020
- Author(s)
  Yanagitani N、Uchibori K、Koike S、Tsukahara、Kitazono、Yoshizawa、Horiike、Ohyanagi、Tambo、Nishikawa、Fujita、Katayama、Nishio M.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 932-939
- DOI
  10.1111/cas.14314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-19H03524, KAKENHI-PLANNED-17H06327
[Journal Article] Overcoming resistance by ALK compound mutation (I1171S + G1269A) after sequential treatment of multiple ALK inhibitors in non‐small cell lung cancer2020
- Author(s)
  Takahashi、Seto、Okada、Uematsu、Uchibori、Tsukahara、Oh‐hara、Fujita、Yanagitani、Nishio、Okubo、Katayama R.
- Journal Title
  
  Thoracic Cancer
  
  Volume: 11 Issue: 3 Pages: 581-587
- DOI
  10.1111/1759-7714.13299
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K16370
[Journal Article] Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB12020
- Author(s)
  Nosol Kamil、Romane Ksenija、Irobalieva Rossitza N.、Alam Amer、Kowal Julia、Fujita Naoya、Locher Kaspar P.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 42 Pages: 26245-26253
- DOI
  10.1073/pnas.2010264117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327, KAKENHI-ORGANIZER-17H06324
[Journal Article] The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models2019
- Author(s)
  Katayama R、Bo G、Togashi N、Miyamoto M、Kiga M、Iwasaki S、Kamai Y、Tominaga Y、Takeda Y、Kagoshima Y、Shimizu Y、Seto Y、Oh-hara T、Koike S、Nakao N、Hanzawa H、Watanabe K、Yoda S、Yanagitani N、Hata AN.、Shaw AT、Nishio M、Fujita N、Isoyama T.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 3604-3604
- DOI
  10.1038/s41467-019-11496-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-19H03524
[Journal Article] Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance2019
- Author(s)
  Okada Koutaroh、Araki Mitsugu、Sakashita Takuya、Ma Biao、Kanada Ryo、Yanagitani Noriko、Horiike Atsushi、Koike Sumie、Oh-hara Tomoko、Watanabe Kana、Tamai Keiichi、Maemondo Makoto、Nishio Makoto、Ishikawa Takeshi、Okuno Yasushi、Fujita Naoya、Katayama Ryohei
- Journal Title
  
  EBioMedicine
  
  Volume: 41 Pages: 105-119
- DOI
  10.1016/j.ebiom.2019.01.019
- NAID
  120006892063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11536, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K00397, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276
[Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer2019
- Author(s)
  Gong Bo, Kiyotani Kazuma, Sakata Seiji, Nagano Seiji, Kumehara Shun, Baba Satoko, Besse Benjamin, Yanagitani Noriko, Friboulet Luc, Nishio Makoto, Takeuchi Kengo, Kawamoto Hiroshi, Fujita Naoya, Katayama Ryohei
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 216 Issue: 4 Pages: 982-1000
- DOI
  10.1084/jem.20180870
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] A safety study of newly generated anti-podoplanin-neutralizing antibody in cynomolgus monkey (Macaca fascicularis).2018
- Author(s)
  Ukaji T, Takemoto A, Katayama R, Takeuchi K, Fujita N
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 70 Pages: 33322-33336
- DOI
  10.18632/oncotarget.26055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07216, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327
[Journal Article] Identification of mutation accumulation as resistance mechanism emerging in first-line osimertinib treatment.2018
- Author(s)
  Ken Uchibori, Naohiko Inase, Makoto Nishio, Naoya Fujita, Ryohei Katayama
- Journal Title
  
  J. Thorac. Oncol.
  
  Volume: 13 Issue: 7 Pages: 915-925
- DOI
  10.1016/j.jtho.2018.04.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715
[Journal Article] 3D culture system containing gellan gum restores oncogene dependence in ROS1 rearrangements non-small cell lung cancer.2018
- Author(s)
  Bo Gong, Tomoko Oh-hara, Naoya Fujita, Ryohei Katayama
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 501 Issue: 2 Pages: 527-533
- DOI
  10.1016/j.bbrc.2018.05.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276
[Journal Article] Platelet-activating factor podoplanin: from discovery to drug development.2017
- Author(s)
  Ai Takemoto, Kenichi Miyata, Naoya Fujita
- Journal Title
  
  Cancer Metastasis Rev.
  
  Volume: 36 Issue: 2 Pages: 225-234
- DOI
  10.1007/s10555-017-9672-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Journal Article] Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation2017
- Author(s)
  Kenichi Miyata, Ai Takemoto, Sakae Okumura, Makoto Nishio, Naoya Fujita
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 4059-4059
- DOI
  10.1038/s41598-017-04324-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327
[Journal Article] 8. Mechanisms of resistance to NTRK inhibitors and therapeutic strategies in NTRK1-rearranged cancers.2017
- Author(s)
  Miho Jane Fuse, Koutaroh Okada, Tomoko Oh-hara, Hayato Ogura, Naoya Fujita, Ryohei Katayama
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 16 Issue: 10 Pages: 2130-2143
- DOI
  10.1158/1535-7163.mct-16-0909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715
[Journal Article] Targeting the Golgi apparatus to overcome acquired resistance of non-small cell lung cancer cells to EGFR tyrosine kinase inhibitors2017
- Author(s)
  Yoshimi Ohashi, Mutsumi Okamura, Ryohei Katayama, Siyang Fang, Saki Tsutsui, Akinobu Akatsuka, Mingde Shan, Hyeong-Wook Choi, Naoya Fujita, Kentaro Yoshimatsu, Isamu Shiina, Takao Yamori, and Shingo Dan
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 2 Pages: 1641-1655
- DOI
  10.18632/oncotarget.22895
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-16H05105, KAKENHI-PROJECT-17K07230, KAKENHI-PROJECT-17H03024
[Journal Article] A critical role of platelet TGF-b release in podoplanin-mediated tumour invasion and metastasis2017
- Author(s)
  Takemoto A, Okitaka M, Takagi S, Takami M, Sato S, Nishio M, Okumura S, Fujita N
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 42186-42186
- DOI
  10.1038/srep42186
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K18419, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327
[Journal Article] APC mutations as a predictive biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.2017
- Author(s)
  Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 16 Issue: 4 Pages: 739-751
- DOI
  10.1158/1535-7163.mct-16-0578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K14409, KAKENHI-PROJECT-15K14412
[Journal Article] TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity2017
- Author(s)
  Hayato Ogura, Yuka Nagatake-Kobayashi, Jun Adachi, Takeshi Tomonaga, Naoya Fujita, Ryohei Katayama
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 5519-5519
- DOI
  10.1038/s41598-017-05736-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04707, KAKENHI-PROJECT-16H04715
[Journal Article] Brigatinib combined with anti-EGFR antibody overcomes osimertinib resistance in EGFR-mutated non-small-cell lung cancer.2017
- Author(s)
  Ken Uchibori, Naohiko Inase, Mitsugu Araki, Mayumi Kamada, Shigeo Sato, Yasushi Okuno, Naoya Fujita, Ryohei Katayama
- Journal Title
  
  Nature Commun.
  
  Volume: 8 Issue: 1 Pages: 14768-14768
- DOI
  10.1038/ncomms14768
- NAID
  120006027079
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-15K14412, KAKENHI-ORGANIZER-17H06324
[Journal Article] P-glycoprotein mediates ceritinib resistance in anaplastic lymphoma kinase-rearranged non-small cell lung cancer.2016
- Author(s)
  Katayama R*, Sakashita T, Yanagitani N, Ninomiya H, Horiike A, Friboulet L, Gainor JF, Motoi N, Dobashi A, Sakata S, Tambo Y, Kitazono S, Sato S, Koike S, Iafrate AJ, Mino-Kenudson M, Ishikawa Y, Shaw AT, Engelman JA, Takeuchi K, Nishio M*, Fujita N*
- Journal Title
  
  EBioMedicine
  
  Volume: 3 Pages: 54-66
- DOI
  10.1016/j.ebiom.2015.12.009
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14412, KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-25250020, KAKENHI-PROJECT-25710015, KAKENHI-PROJECT-15K08373
[Journal Article] Targeting a novel domain in podoplanin for inhibiting platelet-mediated tumor metastasis.2016
- Author(s)
  Sekiguchi T, Takemoto A, Takagi S, Takatori K, Sato S, Takami M, Fujita N.
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 4 Pages: 3934-3934
- DOI
  10.18632/oncotarget.6598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18419, KAKENHI-PROJECT-26640108
[Journal Article] The mERG1a channel modulates skeletal muscle MuRF1, but not MAFbx, expression.2014
- Author(s)
  Pond AL, Nedele C, Wang WH, Wang X, Walther C, Jaeger C, Bradley KS, Du H, Fujita N, Hockerman GH, Hannon KM.
- Journal Title
  
  Muscle Nerve
  
  Volume: 49 Issue: 3 Pages: 378-388
- DOI
  10.1002/mus.23924
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300344
[Journal Article] Adhesion of pancreatic cancer cells in a liver-microvasculature mimicking co-culture correlates with their propensity to form liver-specific metastasis in vivo.2014
- Author(s)
  Mohammad Mahfuz Chowdhury, Mathieu Danoy, Farhana Rahman, Marie Shinohara, Shohei Kaneda, Kiyotaka Shiba, Naoya Fujita, Teruo Fujii and Yasuyuki Sakai
- Journal Title
  
  BioMed Research International
  
  Volume: 241571 Pages: 1-13
- DOI
  10.1155/2014/241571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112008
[Journal Article] Platelets promote osteosarcoma cell growth through activation of the PDGFR-Akt signaling axis.2014
- Author(s)
  Satoshi Takagi, Ai Takemoto, Miho Takami, Tomoko Oh-hara, and Naoya Fujita
- Journal Title
  
  Cancer Sci.
  
  Volume: 105 Issue: 8 Pages: 983-988
- DOI
  10.1111/cas.12464
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-25830125, KAKENHI-PROJECT-25890022
[Journal Article] Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter–mediated drug resistance.2014
- Author(s)
  Aki Aoyama, Ryohei Katayama, Tomoko Oh-hara, Shigeo Sato, Yasushi Okuno and Naoya Fujita
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 13 Issue: 12 Pages: 2978-2990
- DOI
  10.1158/1535-7163.mct-14-0462
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-25710015
[Journal Article] Suppression of Aggrus/podoplanin-induced platelet aggregation and pulmonary metastasis by a single-chain antibody variable region fragment.2014
- Author(s)
  Kenichi Miyata, Satoshi Takagi, Shigeo Sato, Hiroshi Morioka, Kiyotaka Shiba, Tamiko Minamisawa, Miho Takami, and Naoya Fujita
- Journal Title
  
  Cancer Med.
  
  Volume: 3 Issue: 6 Pages: 1595-1604
- DOI
  10.1002/cam4.320
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-25830125
[Journal Article] Two novel ALK mutations mediate acquired resistance to the　next-generation ALK inhibitor alectinib.2014
- Author(s)
  Ryohei Katayama, Luc Friboulet, Sumie Koike, Elizabeth L. Lockerman, Tahsin M. Khan, Justin F. Gainor, A. John Iafrate, Kengo Takeuchi, Makoto Taiji, Yasushi Okuno, Naoya Fujita, Jeffrey A. Engelman, Alice T. Shaw
- Journal Title
  
  Clin. Cancer Res.
  
  Volume: 20 Issue: 22 Pages: 5686-5696
- DOI
  10.1158/1078-0432.ccr-14-1511
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-25250020, KAKENHI-PROJECT-25710015
[Journal Article] The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer.2014
- Author(s)
  Friboulet L, Li N, Katayama R, Lee CC, Gainor JF, Crystal AS, Michellys PY, Awad MM, Yanagitani N, Kim S, Pferdekamper AC, Li J, Kasibhatla S, Sun F, Sun X, Hua S, McNamara P, Mahmood S, Lockerman EL, Fujita N, Nishio M, Harris JL, Shaw AT, Engelman JA
- Journal Title
  
  Cancer Discov.
  
  Volume: 4 Issue: 6 Pages: 662-673
- DOI
  10.1158/2159-8290.cd-13-0846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-25710015
[Journal Article] Adhesion of pancreatic cancer cells in a liver-microvasculature mimicking co-culture correlates with their propensity to form liver-specific metastasis in vivo.2014
- Author(s)
  Chowdhury MM, Danoy M, Rahman F, Shinohara M, Kaneda S, Shiba K, Fujita N, Fujii T, Sakai Y.
- Journal Title
  
  BioMed Res. Int.
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112008
[Journal Article] Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis2014
- Author(s)
  Takagi S, Oh-hara T, Sato S, Gong B, Takami M, Fujita N.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 134 Issue: 11 Pages: 2605-2614
- DOI
  10.1002/ijc.28602
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-25830125
[Journal Article] Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer.2014
- Author(s)
  Ohtsubo K, Yano S, et al.
- Journal Title
  
  Pancreas
  
  Volume: 43 Issue: 7 Pages: 1093-100
- DOI
  10.1097/mpa.0000000000000168
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-24390209
[Journal Article] Cytotoxic Activity of Tivantinib (ARQ 197) Is Not Due Solely to c-MET Inhibition2013
- Author(s)
  Katayama R, Aoyama A, Yamori T, Qi J, Oh-Hara T, Song Y, Engelman JA, Fujita N
- Journal Title
  
  Cancer Res
  
  Volume: 73(10) Issue: 10 Pages: 3087-96
- DOI
  10.1158/0008-5472.can-12-3256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-24300344, KAKENHI-PLANNED-22112008
[Journal Article] Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2.2013
- Author(s)
  Takagi S, Sato S, Oh-hara T, Takami M, Koike S, Mishima Y, Hatake K, Fujita N.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 8 Pages: e73609-e73609
- DOI
  10.1371/journal.pone.0073609
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112008, KAKENHI-PROJECT-25830125
[Journal Article] Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR activating and gatekeeper mutations.2013
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 37 Pages: 4427-35
- DOI
  10.1038/onc.2012.446
- NAID
  120004997024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-25860638, KAKENHI-PLANNED-22112008
[Journal Article] The impact of Aggrus/podoplanin on platelet aggregation and tumor metastasis.2012
- Author(s)
  Fujita, N., et al.
- Journal Title
  
  J Biochem.
  
  Volume: 152 Issue: 5 Pages: 407-413
- DOI
  10.1093/jb/mvs108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701107, KAKENHI-PLANNED-22112008
[Journal Article] In vivo imaging of brain ischemia using an oxygen-dependent degradative fusion prote in probe2012
- Author(s)
  Fujita Y, Kuchimaru T、Kadonosono T, Tanaka S, Hase Y, Tomimoto H, Hiraoka M, Kizaka-Kondoh S, Ihara M, Takahashi R
- Journal Title
  
  PLoS ONE
  
  Volume: 7 Issue: 10 Pages: e48051-e48051
- DOI
  10.1371/journal.pone.0048051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04973, KAKENHI-PROJECT-22700469, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23390233, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112009, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
[Journal Article] The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.2011
- Author(s)
  Nakazawa Y, Fujita N, et al.
- Journal Title
  
  Cancer Research
  
  Volume: 71 Pages: 1146-1155
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22112001
[Journal Article] The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis2011
- Author(s)
  Youya Nakazawa, Hiroyuki Arai, and Naoya Fujita
- Journal Title
  
  Cancer Res
  
  Volume: 71 Issue: 3 Pages: 1146-1155
- DOI
  10.1158/0008-5472.can-10-2695
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650238
[Journal Article] Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.2011
- Author(s)
  Shogo Ehata, Erik Johansson, Ryohei Katayama, Sumie Koike, Akira Watanabe, Yukari Hoshino, Yoko Katsuno, Akiyoshi Komuro, Daizo Koinuma, Mitsunobu R.Kano, Masakazu Yashiro, Kosei Hirakawa, Hiroyuki Aburatani, Naoya Fujita, Kohei Miyazono
- Journal Title
  
  Oncogene 30
  
  Pages: 1693-1705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis.2011
- Author(s)
  Youya Nakazawa, Hiroyuki Arai, Naoya Fujita
- Journal Title
  
  Cancer Res. 71
  
  Pages: 1146-1155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] AP-1-dependent miR-21 expression contributes to chemoresistance in cancer stem cell-like SP cells.2010
- Author(s)
  Aya Misawa, Ryohei Katayama, Sumie Koike, Akihiro Tomida, Toshiki Watanabe, Naoya Fujita
- Journal Title
  
  Oncol.Res. 19
  
  Pages: 23-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] Modulation of Wnt signaling by the nuclear localization of cellular FLIP-L2010
- Author(s)
  Ryohei Katayama, Toshiyasu Ishioka, Shinji Takada, Ritsuko Takada, Naoya Fujita, Takashi Tsuruo, and Mikihiko Naito
- Journal Title
  
  J. Cell Sci
  
  Volume: 123 Issue: 1 Pages: 23-28
- DOI
  10.1242/jcs.058602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650238
[Journal Article] Centrosomal Aki1 and cohesin function in separase-regulated centriole disengagement.2009
- Author(s)
  Akito Nakamura, Hiroyuki Arai, Naoya Fujita
- Journal Title
  
  J.Cell Biol. 187
  
  Pages: 607-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export.2009
- Author(s)
  Ryohei Katayama, Sumie Koike, Shigeo Sato, Yoshikazu Sugimoto, Takashi Tsuruo, Naoya Fujita.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 2060-2068
- NAID
  10027196750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis.2008
- Author(s)
  Youya Nakazawa, Shigeo Sato, Mikihiko Naito, Yukinari Kato, Kazuhiko Mishima, Hiroyuki Arai, Takashi Tsuruo, Naoya Fujita.
- Journal Title
  
  Blood 112
  
  Pages: 1730-1739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Journal Article] Platelet aggregation in the formation of tumor metastasis.2008
- Author(s)
  Takashi Tsuruo, Naoya Fujita
- Journal Title
  
  Proc.Jpn.Acad., Ser.B 84
  
  Pages: 189-198
- NAID
  130000093935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390029
[Patent] EGFR-TKI耐性を獲得した肺癌の治療薬2016
- Inventor(s)
  片山量平、内堀健、藤田直也
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-15K14412
[Patent] EGFR-TKI耐性を獲得した肺癌の治療薬2016
- Inventor(s)
  片山量平、内堀健、藤田直也
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2016-05-17
- Data Source
  KAKENHI-PROJECT-15H02368
[Patent] マウス抗Aggrusモノクローナル抗体2011
- Inventor(s)
  藤田直也、中澤侑也
- Industrial Property Rights Holder
  財団法人癌研究会
- Industrial Property Number
  2011-062686
- Filing Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] LPAR1を標的とした神経膠芽腫の新治療法開発の可能性2023
- Author(s)
  小池清恵、高木聡、竹本愛、藤田直也、片山量平
- Organizer
  第２７回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-23K24167
[Presentation] LPA受容体を介した骨肉腫の悪性化機構の解析2023
- Author(s)
  高木聡、藤田直也
- Organizer
  第３２回日本がん転移学会
- Data Source
  KAKENHI-PROJECT-23K24167
[Presentation] 骨肉腫に有効な新規分子標的薬の探索とその作用機序の解析2022
- Author(s)
  高木聡、小池清恵、竹本愛、藤田直也、片山量平
- Organizer
  第２６回日本がん分子標的治療学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] ポドプラニン依存的なPDGFR活性化を抑制する新規抗体療法の創製2022
- Author(s)
  竹本愛、高木聡、片山量平、藤田直也
- Organizer
  第８１回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24167
[Presentation] 骨肉腫の増殖を阻害する分子標的薬の探索とその作用機序の解析2022
- Author(s)
  高木聡、小池清恵、竹本愛、藤田直也、片山量平
- Organizer
  第８１回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24167
[Presentation] 骨肉腫に有効な新規分子標的薬の探索とその作用機序の解析2022
- Author(s)
  高木聡、小池清恵、竹本愛、藤田直也、片山量平
- Organizer
  第２６回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24167
[Presentation] 腫瘍微小環境を反映した薬剤感受性のための3D共培養腫瘍モデル2022
- Author(s)
  高橋祐生、北野史朗、片山量平、長山聡、藤田直也
- Organizer
  第８１回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 活性化血小板由来LPAはLPAR1活性化を介して骨肉腫の肺転移を促進する2021
- Author(s)
  高木聡、小池清恵、藤田直也、片山量平
- Organizer
  第25回日本がんがん分子標的治療学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Diverse drug resistance mechanisms and overcoming the resistance by drug repurposing2021
- Author(s)
  片山量平、藤田直也
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Osteosarcoma promotes pulmonary metastasis via the release of　lysophosphatidic acid from activated platelets2021
- Author(s)
  高木聡、小池清恵、竹本愛、菅原稔、藤田直也、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] L747P mutation in EGFR mediates the resistance to gefitinib and allosteric inhibitor by losing αC-helix flexibility2021
- Author(s)
  大原智子、藤田直也、西尾誠人、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Identification of molecular targets in early-onset colorectal cancers by sequencing and drug screening2021
- Author(s)
  鈴木麻衣、清水裕貴、丸山航平、大原智子、藤田直也、長山聡、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 血管構造を有する層状間質組織との3D共培養モデルの開発とそれを用いた薬剤感受性試験2021
- Author(s)
  高橋祐生、清水裕貴、北野史朗、長山聡、片山量平、藤田直也
- Organizer
  第８０回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] FLT3阻害薬ギルテリチニブは多剤耐性ALK陽性肺がんの耐性を克服する2021
- Author(s)
  水田隼斗、高木聡、竹本愛、西尾誠人、藤田直也、清水史郎、片山量平
- Organizer
  第25回日本がんがん分子標的治療学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Identification of the achilles heels of colorectal cancer cells harboring BRAF V600E mutation by focused inhibitor library screening2021
- Author(s)
  清水裕貴、丸山航平、鈴木麻衣、大原智子、高橋祐生、長山聡、藤田直也、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] ポドプラニン標的薬の治療効果と毒性を評価するためのノックインマウスの作製2021
- Author(s)
  宇梶太雄、高木聡、藤田直也
- Organizer
  第30回日本がん転移学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Discovery of the FLT3 inhibitor gilteritinib as a novel therapeutic strategy to overcome ALK-TKI resistance2021
- Author(s)
  水田隼斗、竹本愛、高木聡、清水史郎、西尾誠人、藤田直也、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Antitumor drug development and the Japanese Cancer Association2021
- Author(s)
  藤田直也
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Identification of intrinsic resistance mechanisms to KRAS-G12C specific inhibitor using patient derived colorectal cancer cells2021
- Author(s)
  丸山航平、清水裕貴、鈴木麻衣、大原智子、藤田直也、長山聡、片山量平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 骨肉腫は活性型血小板からのリゾホスファチジン酸分泌を介して肺転移を亢進する2021
- Author(s)
  高木聡、小池清恵、竹本愛、菅原稔、藤田直也、片山量平
- Organizer
  第８０回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Platelet-derived lysophosphatidic acid mediated LPAR1 activation as a therapeutic target for osteosarcoma metastasis2021
- Author(s)
  Satoshi Takagi, Yuki Sasaki, Sumie Koike, Ai Takemoto, Yosuke Seto, Mizuki Haraguchi, Takao Ukaji, Tokuichi Kawaguchi, Minoru Sugawara, Masanori Saito, Yuki Funauchi, Keisuke Ae, Seiichi Matsumoto, Naoya Fujita, Ryohei Katayama
- Organizer
  The 25th JFCR-ISCC symposium
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 薬剤耐性変異予測モデル構築に向けたALK-TKIの薬効評価2020
- Author(s)
  水田隼斗、大原智子、小池清恵、岩見真吾、清水史郎、藤田直也、片山量平
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 手術検体からのKRAS G12C 変異大腸がん細胞株の樹立と新規併用療法の探索2020
- Author(s)
  丸山航平、清水裕貴、大原智子、長山聡、藤田直也、片山量平
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Regulation of cellular diversity in tumor microenvironment by platelet activation-inducing molecule Podoplanin2020
- Author(s)
  Satoshi Takagi, Ryohei Katayama, Ai Takemoto, Naoya Fujita
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 薬剤耐性変異予測モデル構築に向けたALK-TKIの薬効評価2020
- Author(s)
  水田隼斗、大原智子、小池清恵、岩見真吾、清水史郎、藤田直也、片山量平
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がん臨床検体を用いた免疫チェックポイント阻害薬耐性機構の探索と分泌型PD-L1バリアント2020
- Author(s)
  片山量平、藤田直也
- Organizer
  第24回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Regulation of cellular diversity in tumor microenvironment by platelet activation-inducing molecule Podoplanin2020
- Author(s)
  Satoshi Takagi, Ryohei Katayama, Ai Takemoto, Naoya Fujita
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] A unique ex vivo tumor model: 3D co-cultured system with cancer and stromal cells including blood microvessels.2020
- Author(s)
  Yuki Takahashi, Kei Tsukamoto, Rii Morimura, Isana Nada, Yuki Shimizu, Ryohei Katayama, Eiji Shinozaki, Satoshi Nagayama, Michiya Matsusaki, Shiro Kitano, Kensei Yamaguchi, Naoya Fujita
- Organizer
  ASCO-GI 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がん臨床検体を用いた免疫チェックポイント阻害薬耐性機構の探索と分泌型PD-L1バリアント2020
- Author(s)
  片山量平、藤田直也
- Organizer
  第24回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 分子プロファイルを用いたBRAF V600E変異陽性大腸がんに対する有効な薬剤の発見2020
- Author(s)
  清水裕貴、丸山航平、瀬戸陽介、キョウ博、大原智子、高橋祐生、長山聡、藤田直也、片山量平
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 血小板活性化因子PDPNを介した腫瘍免疫微小環境の制御2019
- Author(s)
  高木聡、小池清恵、藤田直也、片山量平
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 分泌型PD-L1バリアントを介した免疫チェックポイント治療薬治療耐性機構の発見2019
- Author(s)
  キョウ博、清谷一馬、坂田征士、西尾誠人、竹内賢吾、河本宏、藤田直也、片山量平
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Identification of secreted PD-L1 variants as a decoy of PD-L1 blockade antibody mediating the therapeutic resistance.2019
- Author(s)
  Bo Gong, Kazuma Kiyotani, Seiji Sakata, Ken Takahashi, Seiji Nagano, Shun Kumehara, Satoko Baba, Benjamin Besse, Noriko Yanagitani, Luc Friboulet, Makoto Nishio, Kengo Takeuchi, Hiroshi Kawamoto, Naoya Fujita, and Ryohei Katayama
- Organizer
  2019 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 次世代ROS1/NTRK阻害薬DS-6051bによるCrizotinib耐性の克服2019
- Author(s)
  片山量平、キョウ博、西尾誠人、藤田直也
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 血小板活性化因子PDPNを介した腫瘍免疫微小環境の制御2019
- Author(s)
  高木聡、小池清恵、藤田直也、片山量平
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] ドライバーがん遺伝子の活性化変異が誘導する分子標的薬耐性と新たな脆弱性2019
- Author(s)
  片山量平、岡田康太郎、藤田直也
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 腫瘍組織の多様性とがんの薬物療法抵抗性2019
- Author(s)
  片山量平、キョウ博、瀬戸陽介、藤田直也
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 第 3 世代 ALK 阻害薬 Lorlatinib 耐性を示す ALK-L1256F 変異の特性解析2019
- Author(s)
  大原智子、藤田直也、片山量平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Predication of lorlatinib resistance mechanisms and therapeutic strategies to overcome the resistance in ALK rearranged non-small cell lung cancer.2019
- Author(s)
  Koutaroh Okada, Mitsugu Araki, Tomoko Oh-hara, Makoto Nishio, Yasushi Okuno, Naoya Fujita, Ryohei Katayama
- Organizer
  2019 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がん治療薬開発のこれまでと未来2019
- Author(s)
  藤田直也
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] 肺がんのチロシンキナーゼ阻害薬耐性と免疫チェックポイント阻害薬耐性2019
- Author(s)
  片山量平、藤田直也
- Organizer
  第２３回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 分泌型PD-L1スプライシングバリアントを介した免疫チェックポイント治療薬耐性機構の発見2019
- Author(s)
  キョウ博、西尾誠人、藤田直也、片山量平
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] ポドプラニンを介した腫瘍免疫微小環境の制御2019
- Author(s)
  高木聡、小池清恵、藤田直也、片山量平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] ALK-L1256F変異体は第3世代ALK阻害薬Lorlatinibに高度耐性を示し、第2世代ALK阻害薬Alectinibに高感受性を示す2019
- Author(s)
  岡田康太郎、藤田直也、片山量平
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] EML4-ALK融合タンパク質の新規リン酸化基質の同定とがん化メカニズムの解明2019
- Author(s)
  岡田康太郎, 藤田直也, 西尾誠人, 足立淳, 朝長毅, 片山量平
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Development of a humanized anti-podoplanin antibody inhibiting tumor-dependent platelet activation.2019
- Author(s)
  Ai Takemoto, Nobuhiko Gyobu, Mamoru Kakino, Shinya Fujihara, Naoki Goda, Junya Maeda, Miho Takami, Takao Ukaji, Satoshi Takagi, Ryohei Katayama, Kazue Tsuji-Takayama, Kenji Ichihara, Shinobu Nakayama, Yoshiyuki Ohsugi, and Naoya Fujita
- Organizer
  The 24th ISCC Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がんの進化と多様性により生み出される多様な治療抵抗性機構の解析2019
- Author(s)
  片山量平、キョウ博、西尾誠人、藤田直也
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 血小板活性化因子Podoplaninが作り出すがん免疫逃避環境の解析2019
- Author(s)
  古賀美菜穂、小池清恵、藤田直也、竹本愛、片山量平、高木聡
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Crizotinib resistance mechanisms and potential therapeutic strategies to overcome the resistance in ROS1 rearranged non-small cell lung cancer.2019
- Author(s)
  Ryohei Katayama, Bo Gong, Makoto Nishio, Naoya Fujita
- Organizer
  2019 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] オシメルチニブ初回治療のシーケンスで予想される耐性機構としての多重変異について2018
- Author(s)
  内堀健、西尾誠人、稲瀬直彦、藤田直也、片山量平
- Organizer
  第１６回　日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 次世代 ALK 阻害薬 Lorlatinib 耐性重複変異の発見とその治療戦略の示唆2018
- Author(s)
  岡田康太郎、藤田直也、片山量平
- Organizer
  第２２回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] BRAF V600E変異陽性大腸がんにおける新たなサブグループの発見2018
- Author(s)
  清水裕貴、キョウ博、大原智子、長山聡、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 非接着培養を用いた新規 ROS1 阻害剤評価系の構築2018
- Author(s)
  キョウ博、大原智子、小池清恵、藤田直也、片山量平
- Organizer
  第２２回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] がん患者検体を用いた腫瘍組織の統合解析と新薬開発2018
- Author(s)
  藤田直也
- Organizer
  理研・生命医科学シンポジウム「新たな生命医科学の融合　～ゲノム・免疫・疾患システムを究める～」
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] 肺がんにおける分子標的薬耐性機構解析と耐性克服法予測の可能性2018
- Author(s)
  片山量平、藤田直也
- Organizer
  第７７回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] がん患者検体を用いた腫瘍組織の統合解析と新薬開発2018
- Author(s)
  藤田直也
- Organizer
  理研・生命医科学シンポジウム「新たな生命医科学の融合　～ゲノム・免疫・疾患システムを究める～」
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] KRAS変異大腸がんにおける分子プロファイリングに基づく新規併用治療法の探索2018
- Author(s)
  キョウ博、清水裕貴、大原智子、長山聡、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 初回治療オシメルチニブ後に予想される変異蓄積による獲得耐性機構2018
- Author(s)
  内堀健、北園聡、柳谷典子、堀池篤、西尾誠人、稲瀬直彦、藤田直也、片山量平
- Organizer
  肺癌学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Her2 活性化変異陽性肺がん細胞株の樹立とキナーゼ阻害薬の評価2018
- Author(s)
  大原智子、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がん患者検体を用いた腫瘍組織の統合解析と新薬開発2018
- Author(s)
  藤田直也
- Organizer
  理研・生命医科学シンポジウム「新たな生命医科学の融合　～ゲノム・免疫・疾患システムを究める～」
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] サルポドプラニンの血小板凝集誘導活性におけるPLAG4ドメインの役割2018
- Author(s)
  宇梶太雄、竹本愛、藤田直也
- Organizer
  第27回日本がん転移学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 肺がん分子標的薬耐性メカニズムの探索と耐性機構予測への挑戦2018
- Author(s)
  片山量平、岡田康太郎、藤田直也
- Organizer
  第２２回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Her2 活性化変異陽性肺がん細胞株の樹立とキナーゼ阻害薬の評価2018
- Author(s)
  大原智子、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 初回治療オシメルチニブ後に予想される変異蓄積による獲得耐性機構2018
- Author(s)
  内堀健、北園聡、柳谷典子、堀池篤、西尾誠人、稲瀬直彦、藤田直也、片山量平
- Organizer
  肺癌学会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がんと血小板の結合を標的とする化合物の探索と解析2018
- Author(s)
  竹本愛、片山量平、藤田直也
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] がんと血小板の結合を標的とする化合物の探索と解析2018
- Author(s)
  竹本愛、片山量平、藤田直也
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] BRAF V600E変異陽性大腸がんにおける新たなサブグループの発見2018
- Author(s)
  清水裕貴、キョウ博、大原智子、長山聡、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] サルポドプラニンの血小板凝集誘導活性におけるPLAG4ドメインの役割2018
- Author(s)
  宇梶太雄、竹本愛、藤田直也
- Organizer
  第27回日本がん転移学会学術集会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 三次元培養システムによるRET再構成肺癌細胞の薬物感受性評価システムの確立2018
- Author(s)
  小池清恵、藤田直也、片山量平
- Organizer
  第７７回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] KRAS変異大腸がんにおける分子プロファイリングに基づく新規併用治療法の探索2018
- Author(s)
  キョウ博、清水裕貴、大原智子、長山聡、藤田直也、片山量平
- Organizer
  第７７回　日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] オシメルチニブ初回治療のシーケンスで予想される耐性機構としての多重変異について2018
- Author(s)
  内堀健、西尾誠人、稲瀬直彦、藤田直也、片山量平
- Organizer
  第１６回　日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] 1st and 2nd generation ALK-TKI rescues the next-generation ALK-TKI resistance mediated by double mutations2017
- Author(s)
  Koutaroh Okada, Shigeo Sato, Naoya Fujita, Ryohei Katayama
- Organizer
  第22回International Symposium on Cancer Chemotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Analysis of "drug addiction" mechanisms in the drug-resistant ROS1-rearranged cancer cells.2017
- Author(s)
  Hayato Ogura, Jun Adachi, Takeshi Tomonaga, Naoya Fujita, Ryohei Katayama
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Identification of the molecular mechanisms of resistance to NTRK inhibitors and the potential therapeutic strategies in NTRK1-rearranged cancers.2017
- Author(s)
  Ryohei Katayama, Miho Jane Fuse, Tomoko Oh-hara, Hayato Ogura, Naoya Fujita
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] ブリガチニブと抗EGFR抗体の併用がC797S／T790M変異によるオシメルチニブ耐性を克服する2017
- Author(s)
  内堀健、藤田直也、片山量平
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] G1202R変異型EML4-ALKの変異蓄積による次世代ALK阻害剤Lorlatinib耐性の獲得2017
- Author(s)
  岡田康太郎、藤田直也、片山量平
- Organizer
  第２０回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Driver Oncogene陽性肺がんにおける獲得耐性の分子基盤と新たな治療戦略2017
- Author(s)
  片山量平、藤田直也
- Organizer
  第７６回　日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Inhibitor deprivation mediated excessive oncogene signaling in drug resistant cancers induces both growth and apoptosis signaling.2017
- Author(s)
  Hayato Ogura, Jun Adachi, Takeshi Tomonaga, Naoya Fujita, Ryohei Katayama
- Organizer
  AACR 2017
- Place of Presentation
  ワシントン,　米国
- Year and Date
  2017-04-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14412
[Presentation] Driver oncogene陽性肺がんにおける多様な分子標的薬耐性とその克服法2017
- Author(s)
  片山量平、藤田直也
- Organizer
  第２０回日本がん分子標的治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Driver Oncogene陽性肺がんにおける獲得耐性の分子基盤と新たな治療戦略2017
- Author(s)
  片山量平、藤田直也
- Organizer
  第７６回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Driver oncogene陽性肺がんにおける多様な分子標的薬耐性とその克服法2017
- Author(s)
  片山量平、藤田直也
- Organizer
  第２０回日本がん分子標的治療学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] 1st and 2nd generation ALK-TKI rescues the next-generation ALK-TKI resistance mediated by double mutations.2017
- Author(s)
  Koutaroh Okada, Shigeo Sato, Naoya Fujita, Ryohei Katayama
- Organizer
  The 22nd International Symposium on Cancer Chemotherapy
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Re-sensitization to 1st and 2nd generation ALK-TKI by secondary acquired mutation mediated 3rd ALK-TKI resistance.2017
- Author(s)
  岡田康太郎、藤田直也、片山量平
- Organizer
  平成29年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】」若手支援技術講習会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] ゲノムワイドなshRNAライブラリーを用いた新規転移抑制分子の同定2017
- Author(s)
  宮田憲一、竹本愛、藤田直也
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] ポドプラニンが誘導する血小板TGF- 放出による転移促進機構2017
- Author(s)
  竹本愛、藤田直也
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] Driver Oncogene陽性肺がんにおける獲得耐性の分子基盤と新たな治療戦略2017
- Author(s)
  片山量平、藤田直也
- Organizer
  第７６回　日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] ポドプラニンが誘導する血小板TGF- 放出による転移促進機構2017
- Author(s)
  竹本愛、藤田直也
- Organizer
  第26回日本がん転移学会学術集会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] G1202R変異型EML4-ALKの変異蓄積による次世代ALK阻害剤Lorlatinib耐性の獲得2017
- Author(s)
  岡田康太郎、藤田直也、片山量平
- Organizer
  第２０回日本がん分子標的治療学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] cMET増幅を介したALK阻害薬耐性とその克服法2017
- Author(s)
  小池清恵、藤田直也、片山量平
- Organizer
  第２０回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Resistance mechanisms to NTRK-TKIs in NTRK1 rearranged cancer平2017
- Author(s)
  大原智子、佐藤重夫、藤田直也、片山量平
- Organizer
  第７６回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] cMET増幅を介したALK阻害薬耐性とその克服法2017
- Author(s)
  小池清恵、藤田直也、片山量平
- Organizer
  第２０回日本がん分子標的治療学会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] Development of the molecular targeted therapy in memory of Dr. Takashi Tsuruo2017
- Author(s)
  藤田直也
- Organizer
  第７６回　日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] ブリガチニブと抗EGFR抗体の併用がC797S／T790M変異によるオシメルチニブ耐性を克服する2017
- Author(s)
  内堀健、藤田直也、片山量平
- Organizer
  第７６回　日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Resistance mechanisms to NTRK-TKIs in NTRK1 rearranged cancer2017
- Author(s)
  大原智子、佐藤重夫、藤田直也、片山量平
- Organizer
  第７６回日本癌学会学術総会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] EGFR-C797S/T790M多剤耐性肺癌に対する新規療法2017
- Author(s)
  内堀健、稲瀬直彦、荒木望嗣、鎌田真由美、佐藤重男、奥野恭史、藤田直也、片山量平
- Organizer
  第15回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-ORGANIZER-17H06324
[Presentation] EGFR-C797S/T790M多剤耐性肺癌に対する新規療法2017
- Author(s)
  内堀健、稲瀬直彦、荒木望嗣、鎌田真由美、佐藤重男、奥野恭史、藤田直也、片山量平
- Organizer
  第15回日本臨床腫瘍学会学術集会（JSMO）
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Resistance mechanisms to NTRK-TKIs in NTRK1 rearranged cancer2017
- Author(s)
  大原智子、佐藤重夫、藤田直也、片山量平
- Organizer
  第７６回　日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06327
[Presentation] cMET gene amplification mediated ALK-TKI resistance2016
- Author(s)
  大原智子、西尾誠人、藤田直也、片山量平
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Excessive oncogene signaling induced “drug addiction” characteristic2016
- Author(s)
  小倉隼人、足立淳、朝長毅、藤田直也、片山量平
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] がんの難治性に関わる治療薬耐性化と転移を克服する薬剤の探索2016
- Author(s)
  藤田直也
- Organizer
  第814回　千葉県がんセンター集談会
- Place of Presentation
  千葉県がんセンター研究所、千葉
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] FGFR3またはcMETの過剰活性化を介したALK阻害薬耐性機構の発見2016
- Author(s)
  Ryohei Katayama, Sumie Koike, Tomoko Oh-hara, Makoto Nishio, Naoya Fujita
- Organizer
  第20回日本がん分子標的治療学会学術総会
- Place of Presentation
  大分県別府市
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15K14412
[Presentation] FGFR3またはcMETの過剰活性化を介したALK阻害薬耐性機構の発見2016
- Author(s)
  Ryohei Katayama, Sumie Koike, Tomoko Oh-hara, Makoto Nishio, Naoya Fujita
- Organizer
  第２０回日本がん分子標的治療学会
- Place of Presentation
  別府ビーコンプラザ、大分
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Identifications of inhibitors which can overcome acquired resistance to third-generation EGFR-TKI2016
- Author(s)
  Ken Uchibori, Naoya Fujita, Ryohei Katayama
- Organizer
  第７５回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] がんの再発に関わる薬剤耐性と転移を標的にした創薬2016
- Author(s)
  藤田直也
- Organizer
  第３回　次世代バイオ・医療技術研究会
- Place of Presentation
  東京大学生産技術研究所、東京
- Year and Date
  2016-01-07
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] ABCトランスポーターを介したALK阻害薬耐性2016
- Author(s)
  小池清恵、藤田直也、片山量平
- Organizer
  第２０回日本がん分子標的治療学会
- Place of Presentation
  別府ビーコンプラザ、大分
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] 第3世代EGFR-TKIの耐性機構C797S変異に対する阻害薬の発見2016
- Author(s)
  内堀健、藤田直也、片山量平、稲瀬直彦
- Organizer
  第５７回日本肺癌学会学術集会
- Place of Presentation
  福岡国際会議場、福岡
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Characterization of the ALK-TKI resistant cells mediated by secondary mutations or bypass pathway activation2015
- Author(s)
  小池清恵、坂下卓也、西尾誠人、藤田直也、片山量平
- Organizer
  第７４回　日本癌学会総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K14412
[Presentation] 培養細胞株と患者検体を用いたALK阻害薬耐性機構の解析2015
- Author(s)
  片山量平、小池清恵、西尾誠人、藤田直也
- Organizer
  第１９回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル、愛媛
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15K14412
[Presentation] Targeting tumor-induced platelet aggregation for cancer therapy2015
- Author(s)
  藤田直也、竹本愛
- Organizer
  第74回　日本癌学会総会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26640108
[Presentation] キナーゼ融合型がん遺伝子を標的にした治療薬への耐性化機構の解明とその克服2015
- Author(s)
  藤田直也
- Organizer
  平成27年度「がん研究分野の特性等を踏まえた支援活動」　公開シンポジウム
- Place of Presentation
  一橋講堂、東京
- Year and Date
  2015-09-09
- Invited
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Targeting platelet-tumor interaction for cancer therapy2015
- Author(s)
  Naoya Fujita
- Organizer
  Lithuania-Japan Joint Life Science Symposium
- Place of Presentation
  東京大学、東京
- Year and Date
  2015-10-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640108
[Presentation] 血小板によるがんの増殖と転移の促進2015
- Author(s)
  藤田直也
- Organizer
  Recent Advance in Tumor Angiogenesis 2014
- Place of Presentation
  グランドホテル浜松、浜松
- Year and Date
  2015-01-24
- Invited
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Novel ceritinib resistance mechanisms: new resistant mutation, fibroblast growth factor receptor 3 overexpression and cMET amplification-mediated ceritinib resistance2015
- Author(s)
  yohei Katayama, Takuya Sakashita, Noriko Yanagitani, Kengo Takeuchi, Makoto Nishio, Naoya Fujita
- Organizer
  AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
- Place of Presentation
  米国、ボストン
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14412
[Presentation] 培養細胞株と患者検体を用いたALK阻害薬耐性機構の解析2015
- Author(s)
  片山量平、小池清恵、西尾誠人、藤田直也
- Organizer
  第１９回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル、愛媛
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-15H02368
[Presentation] Aggrus依存的な血小板凝集はEMTを介してがん転移を促進する2015
- Author(s)
  竹本愛, 大原智子, 藤田直也
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル、愛媛
- Year and Date
  2015-06-10
- Invited
- Data Source
  KAKENHI-PROJECT-26640108
[Presentation] 新規血小板凝集促進因子Aggrusを標的とした分子標的2014
- Author(s)
  藤田直也
- Organizer
  平成25年度彩都産学官連携シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター、大阪
- Invited
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] 新規足場蛋白Aki1を標的としたEGFR遺伝子変異陽性肺がんの制御2013
- Author(s)
  山田忠明、竹内伸司、藤田直也、矢野聖二
- Organizer
  第１７回日本がん分子標的治療研究会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] キナーゼ阻害薬とその耐性化機構2013
- Author(s)
  藤田直也
- Organizer
  第１７回日本がん分子標的治療研究会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Induction of synergy suppression by combination of kinase inhibitors using ALK inhibitor resistant cell lines2013
- Author(s)
  赤松香奈子、片山量平、田中義久、藤田直也、奥野恭史
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、神戸
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Antitumor activity of tivantinib (ARQ 197) is due to disruption of microtubule assembly in addition to c-MET inhibition.2013
- Author(s)
  Aki Aoyama, Ryohei Katayama, Takao Yamori, Jie Qi, Tomoko Oh-hara, Youngchul Song, Jeffrey A. Engelman and Naoya Fujita
- Organizer
  The 18th International Symposium on Cancer Chemotherapy
- Place of Presentation
  未来館ホール、東京
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Suppression of tumor growth in vivo by a murine/human chimeric anti-Aggrus neutralizing antibody2013
- Author(s)
  高木聡、佐藤重男、藤田直也
- Organizer
  第７２回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Aggrus/podoplaninを標的とした中和抗体による抗転移効果と抗腫瘍効果2013
- Author(s)
  高木聡、藤田直也
- Organizer
  第22回日本がん転移学会学術集会
- Place of Presentation
  ホテルブエナビスタ、松本
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Patterns of relapse and prognosis after Crizotinib therapy failure in ALK+ Non-small cell lung cancer.2013
- Author(s)
  Noriko Yanagitani, Hironari Nishizawa, Ryohei Katayama, Hiroshi Kobayashi, Hiroshi Gyoutoku, Takeshi Uenami, Yuichi Tambo, Keita Kudo, Fumiyoshi Ohyanagi, Atsushi Horiike, Hironori Ninomiya, Noriko Motoi, Kengo Takeuchi, Yuichi Ishikawa, Naoya Fujita, Takeshi Horai, Makoto Nishio.
- Organizer
  15th World Conference on Lung Cancer
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Aggrus/PodoplaninはRho/ROCKシグナルを活性化し胸膜中皮腫の進展を促進する2013
- Author(s)
  竹内伸司　山田忠明　藤田直也　石井源一郎　落合淳志　矢野聖二
- Organizer
  第53回　日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム、東京
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Development of anti-Aggrus/podoplanin antibodies suppressing hematogenous metastasis and tumor growth in vivo2013
- Author(s)
  Naoya Fujita
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Invited
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] Antitumor activity of Tivantinib (ARQ 197) is due to inhibition of tubulin polymerization in addition to c-Met inhibition.2013
- Author(s)
  Ryohei Katayama, Aki Aoyama, Takao Yamori, Jie Qi, Tomoko Oh-hara, Youngchul Song, Jeffrey A. Engelman, Naoya Fujita
- Organizer
  The 104th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington, DC, USA
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Tivantinib(ARQ197)の抗腫瘍効果に関わる新規分子標的の同定2013
- Author(s)
  青山暁、片山量平、矢守隆夫、大原智子、藤田直也
- Organizer
  第１７回日本がん分子標的治療研究会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Identification of the 2nd generation ALK inhibitor-resistance mechanism in NSCLC harboring EML4-ALK2013
- Author(s)
  小池清恵, 片山量平, 藤田直也
- Organizer
  第７２回　日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Development of anti-Aggrus/podoplanin antibodies suppressing hematogenous metastasis and tumor growth in vivo2013
- Author(s)
  藤田直也、高木聡
- Organizer
  第７２回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Cytotxic Activity of Tivantinib (ARQ197) is not due solely to c-MET inhibition2013
- Author(s)
  片山量平, 大原智子, 矢守隆夫, 藤田直也
- Organizer
  第７２回　日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Role of Aggrus/podoplanin-induced platelet aggregation in tumor growth and metastasis formation.2012
- Author(s)
  Naoya Fujita
- Organizer
  The 9th Nikko International Symposium 2012 "Understanding complex network system in disease biology"
- Place of Presentation
  自治医科大学、栃木
- Invited
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Targeting tumor-host interaction for developing anti-metastatic therapies.2012
- Author(s)
  Naoya Fujita
- Organizer
  JST CREST/SICP/ERATO Joint Symposium on " Microfluidics for Tissue and Cell Applications"
- Place of Presentation
  東京大学、東京
- Year and Date
  2012-11-05
- Invited
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Targeting tumor-host interaction for developing anti-metastatic therapies2012
- Author(s)
  Naoya Fujita
- Organizer
  JST CREST/SICP/ERATO Joint Symposium on " Microfluidics for Tissue and Cell Applications
- Place of Presentation
  東京大学生産技術研究所（東京）
- Year and Date
  2012-11-05
- Invited
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] The role of tumor-platelet interaction in hematogenous metastasis.2012
- Author(s)
  Naoya Fujita
- Organizer
  The 2nd International Symposium by JSPS Core-to-Core Program "TGF-β Family: Signal Network and Tumor Microenvironment"
- Place of Presentation
  昭和薬科大学、東京
- Year and Date
  2012-10-29
- Invited
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] キナーゼ阻害薬(Year in Review)2012
- Author(s)
  Naoya Fujita
- Organizer
  第16回日本がん分子標的治療学会
- Place of Presentation
  西日本総合展示場、北九州
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Involvement of platelet-tumor interaction in tumor cell survival and metastasis.2012
- Author(s)
  Naoya Fujita
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌、札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] 転移先微小環境内におけるがんの生存と血行性転移促進2011
- Author(s)
  藤田直也
- Organizer
  第1回新学術領域公開ワークショップ
- Place of Presentation
  東京大学、東京
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22650238
[Presentation] がん分子標的の探索から治療薬開発への展開とその現状2011
- Author(s)
  藤田直也
- Organizer
  第141回日本医学会シンポジウム
- Place of Presentation
  日本医師会館大講堂、東京(招待講演)
- Year and Date
  2011-12-08
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] 転移先微小環境内におけるがんの生存と血行性転移促進2011
- Author(s)
  藤田直也
- Organizer
  第1回新学術領域公開ワークショップ
- Place of Presentation
  東京
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-22650238
[Presentation] Oncomir miR-21による癌幹細胞様SP細胞の制御機構の解明2011
- Author(s)
  三沢彩,片山量平,小池清恵,冨田章弘,渡邉俊樹,井上聡,藤田直也
- Organizer
  第11回東京大学生命科学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-22650238
[Presentation] 新規ヒストンメチルトランスフェラーゼMerm1は、腫瘍抑制因子Zac1の発現抑制を介して、癌転移を促進する2010
- Author(s)
  Youya Nakazawa、Hiroyuki Arai、Naoya Fujita
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪(口演)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] 抗がん剤耐性機構の解明とその克服(がん研究入門コース)2010
- Author(s)
  藤田直也
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター(大阪府大阪市)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] A novel histone methyltransferase Merm1 promotes metastasis by Zac1 silencing2010
- Author(s)
  Youya Nakazawa、Hiroyuki Arai、Naoya Fujita
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22650238
[Presentation] AP-1依存的なmiR-21の発現亢進によるがん幹細胞様 SP 細胞の抗がん剤耐性化2010
- Author(s)
  Aya Misawa、Ryohei Katayama、Sumie Koike、Akihiro Tomida、Toshiki Watanabe、Naoya Fujita
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪(示説)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] p27^<kip1> carboxy-terminal derived peptide possesses anti-tumor activity by inhibiting proto-oncogene pim-1 kinase2010
- Author(s)
  Daisuke Morishita、Miho Takami、Ryohei Katayama、Shigeo Sato、Kazuhisa Sekimizu、Shigeyuki Yokoyama、Naoya Fujita
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22650238
[Presentation] Molecular mechanisms of pulmonary metastasis induced by a tumor cell surface Aggrus protein2009
- Author(s)
  藤田直也
- Organizer
  The 14^<th> JFCR-ISCC symposium
- Place of Presentation
  ホテルニッコー東京、東京
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] 幹細胞様がん細胞のABCトランスポーターと抗がん剤耐性2009
- Author(s)
  Naoya Fujita
- Organizer
  第13回日本がん分子標的治療学会総会
- Place of Presentation
  ホテルクレメント徳島、徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20659014
[Presentation] Molecular mechanisms of pulmonary metastasis induced by a tumor cell surface Aggrus protein2009
- Author(s)
  Naoya Fujita
- Organizer
  The 14^<th> JFCR-ISCC symposium(第14回癌研-国際癌化学療法シンポジウム)
- Place of Presentation
  東京(招待講演)
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] Hematogenous metastasis induced by platelet aggregation-inducing factor Aggrus2009
- Author(s)
  Naoya Fujita
- Organizer
  The 14th IMCB Symposium(第14回東京大学分子細胞生物学研究所シンポジウム)
- Place of Presentation
  東京(招待講演)
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] Hematogenous metastasis induced by platelet aggregation-inducing factor Aggrus2009
- Author(s)
  藤田直也
- Organizer
  The 14^<th> IMCB Symposium
- Place of Presentation
  東京大学安田講堂、東京
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] Aggrusを介した癌転移の促進機構2009
- Author(s)
  藤田直也
- Organizer
  第137回染色体研究会
- Place of Presentation
  東京(招待講演)
- Year and Date
  2009-04-11
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] 分子標的治療薬による癌化学療法の進化と個別化治療への展開2009
- Author(s)
  藤田直也
- Organizer
  第57回日本化学療法学会
- Place of Presentation
  ホテルニッコー東京、東京
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20015046
[Presentation] Aggrus を介した癌転移の促進機構2009
- Author(s)
  藤田直也
- Organizer
  第137回染色体研究会
- Place of Presentation
  国立国際医療センター、東京
- Year and Date
  2009-04-11
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] 乳癌の癌幹細胞と抗癌剤耐性2008
- Author(s)
  藤田直也
- Organizer
  第8回関東ホルモンと癌研究会
- Place of Presentation
  癌研究会吉田講堂、東京
- Year and Date
  2008-01-19
- Data Source
  KAKENHI-PROJECT-18015008
[Presentation] 新規TRAIL受容体結合タンパク質PRMT5によるNF-κBの活性化を介したTRAIL誘導性細胞死の制御2008
- Author(s)
  藤田直也
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] Drug resistance mediated by survival- and growth-promoting signaling pathways2008
- Author(s)
  藤田直也
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] Drug resistance mediated by survival- and growth-promoting signaling pathways2008
- Author(s)
  藤田直也
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20659014
[Presentation] 新規TRAIL受容体結合タンパク質PRMT5によるNF-κBの活性化を介したTRAIL誘導性細胞死の制御2008
- Author(s)
  藤田直也
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20659014
[Presentation] 乳癌の癌幹細胞と抗癌剤耐性2008
- Author(s)
  藤田直也
- Organizer
  第8回関東ホルモンと癌研究会
- Place of Presentation
  癌研究会吉田講堂、東京
- Year and Date
  2008-01-19
- Data Source
  KAKENHI-PROJECT-18390020
[Presentation] Drug resistance mediated by survival-and growth-promoting signaling pathways.2008
- Author(s)
  藤田直也
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋国際会議場、愛知
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20015046
[Presentation] Chemoresistance in breast cancer stem-like cells2008
- Author(s)
  Naoya Fujita
- Organizer
  Second JCA-AACR Special Joint Conference
- Place of Presentation
  淡路路夢舞台、兵庫
- Year and Date
  2008-07-16
- Data Source
  KAKENHI-PROJECT-20659014
[Presentation] Chemoresistance in breast cancer stem-like cells2008
- Author(s)
  Naoya Fujita
- Organizer
  Second JCA-AACR Special Joint Conference
- Place of Presentation
  淡路夢舞台、兵庫
- Year and Date
  2008-07-16
- Data Source
  KAKENHI-PROJECT-20390029
[Presentation] 新規TRAIL受容体結合タンパク質PRMT5によるNF-κBの活性化を介したTRAIL誘導性細胞死の制御2008
- Author(s)
  藤田直也
- Organizer
  第12回がん分子標的治療研究会
- Place of Presentation
  学術総合センター、東京
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20015046
[Presentation] Chemoresistance in breast cancer stem-like cells2008
- Author(s)
  Naoya Fujita
- Organizer
  Second JCA-AACR Special Joint Conference
- Place of Presentation
  淡路夢舞台、兵庫
- Year and Date
  2008-07-16
- Data Source
  KAKENHI-PROJECT-20015046
[Presentation] Aggrus/podoplanin-induced platelet aggregation in metastasis formation2007
- Author(s)
  藤田直也
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18015008
[Presentation] Aggrus/podoplanin-induced platelet aggregation in metastasis formation.2007
- Author(s)
  Naoya Fujita, et. al.
- Organizer
  The 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390020
[Presentation] Aggrus/podoplanin-induced platelet aggregation in metastasis formation2007
- Author(s)
  藤田直也
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390020
[Presentation] Discovery of Aggrus/podoplanin as a metastasis-promoting platelet aggregation-inducing factor.2006
- Author(s)
  Naoya Fujita, et. al.
- Organizer
  The 11th Intemational Congress of Metastasis Research Society
- Place of Presentation
  Tokushima
- Year and Date
  2006-09-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390020
[Presentation] Discovery of Aggrus/podoplanin as a metastasis-promoting platelet aggregation-inducing factor2006
- Author(s)
  藤田直也
- Organizer
  第11回国際転移学会総会
- Place of Presentation
  ホテルクレメント徳島、徳島
- Year and Date
  2006-09-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390020
[Presentation] Expression of Aggrus/podoplanin in bladder cancer and its role in pulmonary metastasis
- Author(s)
  大原智子、高木聡、竹本愛、佐藤重男、高見美穂、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Identification of and overcoming the crizotinib and ceritinib resistance in ROS1-rearranged lung cancers
- Author(s)
  小林由佳、片山量平、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] 一本鎖抗体によるAggrus/podoplanin依存的な血小板凝集及び肺転移の抑制
- Author(s)
  宮田憲一、高木聡、藤田　直也
- Organizer
  第23回日本がん転移学会
- Place of Presentation
  金沢市文化ホール、金沢
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Identification of the alectinib-resistance mechanism in NSCLC harboring ALK rearrangement
- Author(s)
  小池清恵、片山量平、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Acquired resistance in ALK rearranged NSCLC: Mechanisms of and strategies to overcome resistance
- Author(s)
  片山量平、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Therapeutic strategies to overcome the crizotinib resistance in ROS1-rearranged lung cancers.
- Author(s)
  Ryohei Katayama, Yuka Kobayashi, Sumie Koike, Naoya Fujita
- Organizer
  Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Platelets promote the malignancy of osteosarcoma through activation of the PDGFR-Akt signaling
- Author(s)
  竹本愛、高木聡、高見美穂、大原智子、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Regulation of tumor microenvironment and metastasis by interaction with platelets
- Author(s)
  藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640108
[Presentation] New resistance mechanisms to second-generation ALK inhibitor Ceritinib (LDK378)
- Author(s)
  坂下卓矢、片山量平、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] Aggrus-induced platelet aggregation promotes tumor metastasis by enhancing EMT.
- Author(s)
  Ai Takemoto, Satoshi Takagi, Mina Okitaka, Miho Takami, Shigeo Sato, Tomoko Oh-hara, and Naoya Fujita
- Organizer
  Joint International Symposium on TGF-β and Cancer
- Place of Presentation
  つくば国際会議場、つくば
- Year and Date
  2015-01-12 – 2015-01-13
- Data Source
  KAKENHI-PLANNED-22112008
[Presentation] Tivantinib (ARQ197) shows antitumor activity by reduced tubulin polymerization and overcomes tubulin binder-resistance
- Author(s)
  青山暁、片山量平、藤田直也
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] ALK阻害薬への耐性とその克服
- Author(s)
  藤田直也
- Organizer
  日本癌学会シンポジウム/共同利用・共同研究拠点シンポジウム
- Place of Presentation
  石川県立音楽堂交流ホール、金沢
- Year and Date
  2015-01-21 – 2015-01-22
- Invited
- Data Source
  KAKENHI-PROJECT-24300344
[Presentation] 膵癌における新規足場蛋白Akt kinase-interacting protein 1 (Aki1) の発現
- Author(s)
  大坪公士郎, 藤田直也、矢野聖二
- Organizer
  第45回日本膵臓学会大会
- Place of Presentation
  北九州国際会議場、北九州
- Year and Date
  2014-07-11 – 2014-07-12
- Data Source
  KAKENHI-PROJECT-24300344
[]
[]

1. KATAYAMA Ryohei (60435542)

# of Collaborated Projects: 4 results

# of Collaborated Products: 62 results
2. SATO Shigeo

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. TAKAMI Miho

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
4. MIYAZONO Kohei (90209908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. AKIYAMA Tetsu (70150745)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 竹本愛 (20706494)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
7. MIYATA Kenichi

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
8. TAKATORI Kazuki

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. 越川直彦 (70334282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 高木聡 (20582240)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
11. NAKAZAWA Youya

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
12. OH-HARA Tomoko

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
13. SEKIGUCHI Takaya

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. FUSE Miho Jane

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. TAKAKURA Nobuyuki (80291954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SATO Yasufumi (50178779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. YANO Seiji (30294672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
18. KONDOH Shinae (40314182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MINAMI Takashi (00345141)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HEISSIG Beate (30372931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ABURATANI Hiroyuki (10202657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MANO Hiroyuki (90240704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NAKA Kazuhito (70372688)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. HARA Eiji (80263268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. OGO Naohisa (20501307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Tomonaga Takeshi (80227644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 鶴尾隆 (00012667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 冨田章弘 (40251483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 清宮啓之 (50280623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 馬島哲夫 (30311228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 内藤幹彦 (00198011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. 杉本芳一 (10179161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. 口野嘉幸 (60124418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. 中島琢磨 (90256678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. 田沼靖一 (10142449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. 三浦正幸 (50202338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. 松沢昭雄 (50012745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. 西尾誠人 (00281593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. 長山聡 (70362499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 田崎創平 (50713020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. MISAWA Aya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
43. OKITAKA Mina

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
44. KOIKE Sumie

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
45. NODA Sachie

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. AOYAMA Aki

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
47. KOBAYASHI Yuka

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
48. SAKASHITA Takuya

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
49. HIRAIAWA Yukari

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. ISHIKAWA Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 矢守隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 石川雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 坂田征士

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujita Naoya 藤田 直也

FUJITA Naoya 藤田 直也

Research Projects

Research Products

Co-Researchers

Integrated analysis and regulation of cellular diversityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tumor growth and metastasis via podoplanin-dependent platelet aggregationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrated analysis and regulation of cellular diversityArea Organizer

Area Organizer

Project Period (FY)

Research Category

Integrated analysis and regulation of cellular diversityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integrated analysis and regulation of cellular diversity for disease treatmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of drug resistant mechnism by kinome analysis using patient derived cultured cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of acquired resistance to targeted therapies and search for overcoming drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mutual exclusiveness of driver oncogenes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of platelet-mediated tumor suppression and development of the anti-tumor therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of EGFR-TKI resistance and development of overcoming drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Integrative Research on Cancer Microenvironment Network

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular analysis of metastasis-related tumor microenvironment and development of new anti-metastatic therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation of Pim kinase inhibitors based on structural and post-transcriptional analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Fujita Naoya 藤田直也

FUJITA Naoya 藤田直也