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Ogawa Haruo  小川 治夫

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OGAWA Haruo  小川 治夫

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Researcher Number 40292726
Other IDs
External Links
Affiliation (Current) 2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 京都大学, 薬学研究科, 准教授
2017 – 2021: 東京大学, 定量生命科学研究所, 准教授
2007 – 2016: 東京大学, 分子細胞生物学研究所, 准教授
2002: 東大, 分子細胞生物学研究所, 助手
2001: The University of Tokyo, Institute of Molecular and Cellular Biosciences, Research associate, 分子細胞生物学研究所, 助手 … More
1999: 東京大学, 分子細胞生物学研究所, 助手
1997 – 1998: The University of Tokyo, Faculty of Medicine, Research Associate, 大学院・医学系研究科, 助手
1997: 東京大学, 大学院医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Biophysics / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 43020:Structural biochemistry-related / Complex systems
Except Principal Investigator
Basic Section 48020:Physiology-related / Biophysics / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related … More / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Basic Section 47040:Pharmacology-related / Basic Section 43020:Structural biochemistry-related / Biophysics / Biological Sciences Less
Keywords
Principal Investigator
膜蛋白質 / イオンポンプ蛋白質 / X線結晶解析 / X線結晶構造解析 / クライオ電子顕微鏡 / リアノジン受容体 / 大量発現 / 膜1回貫通型受容体 / 立体構造解析 / 膜タンパク質 … More / 構造解析 / イオンチャネル / カルシウムチャネル / イオンポンプタンパク質 / 超巨大蛋白質 / アデノウィルス / 心収縮 / 膜受容体 / ホルモン / ANP / 受容体 / x-ray crystallography / active transport / ion pump / P-type ATPase / バキュロウィルス / SF9 / 界面活性剤 / 二次元結晶 / アセチルコリン受容体 … More
Except Principal Investigator
イオンポンプ / 膜蛋白質 / 骨格筋 / リアノジン受容体 / 結晶解析 / ATPase / 能動輸送 / クライオ電子顕微鏡 / カルシウムイオン / 創薬 / 筋小胞体 / 興奮収縮連関 / カルシウムチャネル / カルシウム / 悪性高熱症 / 蛋白質 / 構造生物学 / membrane proteins / active transport / ion pump / 構造解析 / エネルギー変換 / 電子線結晶解析 / X線結晶解析 / 蛋白質結晶 / 糖転移酵素 / O-マンノース型糖鎖 / 神経疾患 / 筋疾患 / 糖鎖 / X線回折 / 1分子計測 / カルシウム遊離チャネル / 筋収縮 / 構造薬理学 / 輸送体 / 分子認識 / 心筋 / 機能抑制型変異 / 抗不整脈薬 / 不整脈 / 2型リアノジン受容体 / GCase受容体 / グアニル酸シクラーゼ受容体 / ナトリウム利尿ペプチド / GC受容体 / イオンチャネル / 機能解析 / サブタイプ / 小胞体 / 分子動力学計算 / リアノジン / 熱 / Ca2+放出 / 生物物理 / X-ray crystallography / electron crystallography / Protein crystals / structural analysis / electron microscopy / three-dimensional structure / calcium pump / 電子顕微鏡 / 三次元構造 / カルシウムポンプ / エネルギー交換 / 脂質二重膜 Less
  • Research Projects

    (24 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (34 People)
  •  Structural basis of diversed and dynamic substrate recognition mechanism of multidrug transporter by chemical trapping

    • Principal Investigator
      加藤 博章
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
    • Research Institution
      Kyoto University
  •  創薬へ向けた心筋型リアノジン受容体の活性制御機構の構造的解明Principal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
    • Research Institution
      Kyoto University
  •  X線1分子動態計測による膜蛋白質マルチセンシング機構の動的解明

    • Principal Investigator
      清水 啓史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      University of Fukui
  •  Molecular basis and physiological significance of O-mannosyl glycans in mammals

    • Principal Investigator
      萬谷 博
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
  •  Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agents

    • Principal Investigator
      呉林 なごみ
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Juntendo University
  •  膜1回貫通型受容体を対象にした「構造生物学での最後のフロンティア」解消への挑戦Principal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Kyoto University
  •  Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system

    • Principal Investigator
      村山 尚
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Juntendo University
  •  Structural biology of GC-A receptor - Mechanism underlying peptide recognition and intramolecular signal transduction

    • Principal Investigator
      Kodama Masami
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      University of Shizuoka
      Juntendo University
  •  Structural analysis of the gating mechanism of cardiac ryanodine receptorPrincipal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Kyoto University
  •  Analysis of a novel ryanodine receptor modulation mechanism using physiological experiments and molecular dynamics calculations

    • Principal Investigator
      Yamazawa Toshio
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Jikei University School of Medicine
  •  Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators

    • Principal Investigator
      Murayama Takashi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48020:Physiology-related
    • Research Institution
      Juntendo University
  •  Structural elucidation of active transport by P-type ATPases

    • Principal Investigator
      Toyoshima Chikashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Elucidation of tissue-specific calcium ion regulation mechanism by calcium pump by crystallographyPrincipal Investigator

    • Principal Investigator
      Ogawa Haruo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  PLN/SERCA2aレギュラトームによる心収縮調節機構の解明Principal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Structural analysis of PLN/SERCA regulatome toward understanding of the mechanism of Ca2+-regulation in the cardiac muscle cellsPrincipal Investigator

    • Principal Investigator
      Ogawa Haruo
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Establishment of an over-expression system for mammalian large membrane proteinsPrincipal Investigator

    • Principal Investigator
      Ogawa Haruo
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Structural biology of membrane transporters with a view to drug development

    • Principal Investigator
      TOYOSHIMA Chikashi
    • Project Period (FY)
      2011 – 2016
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Structure and functional analysis of the GCase receptor by x-rayPrincipal Investigator

    • Principal Investigator
      OGAWA Haruo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Structural biology of ion transporters

    • Principal Investigator
      TOYOSHIMA Chikashi
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  イオン能動輸送のメカニズム解明へ向けた立体構造解析Principal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Ca-ATPaseの電子線・X線結晶解析

    • Principal Investigator
      TOYOSHIMA Chikashi
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Crystallographics study of active ion transport

    • Principal Investigator
      TOYOSHIMA Chikashi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  ムスカリン性アセチルコリン受容体の2次元結晶化Principal Investigator

    • Principal Investigator
      小川 治夫
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo
  •  Structural Basis of Active Transport by Ion Pumps

    • Principal Investigator
      TOYOSHIMA Chikashi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Biophysics
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2007 Other

All Journal Article Presentation

  • [Journal Article] Structural insight into hormone recognition by the natriuretic peptide receptor-A2024

    • Author(s)
      Haruo Ogawa, Masami Kodama
    • Journal Title

      The FEBS Journal

      Volume: 04 March 2024 Issue: 10 Pages: 114-114

    • DOI

      10.1111/febs.17104

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K19375, KAKENHI-PROJECT-21K06044
  • [Journal Article] Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations2022

    • Author(s)
      Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 2821-2821

    • DOI

      10.1038/s41467-022-30429-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02411, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
  • [Journal Article] ナトリウム利尿ペプチド受容体の基質認識とその活性化機構2021

    • Author(s)
      小川 治夫、児玉 昌美
    • Journal Title

      循環器内科

      Volume: 89 Pages: 454-462

    • NAID

      40022569004

    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Journal Article] Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation2021

    • Author(s)
      Itoh Hideki、Murayama Takashi、Kurebayashi Nagomi、Ohno Seiko、Kobayashi Takuya、Fujii Yusuke、Watanabe Masaya、Ogawa Haruo、Anzai Toshihisa、Horie Minoru
    • Journal Title

      Journal of Electrocardiology

      Volume: 69 Pages: 111-118

    • DOI

      10.1016/j.jelectrocard.2021.09.015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K08473, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-21H02411
  • [Journal Article] Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother.2021

    • Author(s)
      Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y
    • Journal Title

      Biomed Pharmacother.

      Volume: 141 Pages: 111800-111800

    • DOI

      10.1016/j.biopha.2021.111800

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08866, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-19H03404
  • [Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020

    • Author(s)
      Yamazawa Toshiko、Ogawa Haruo、Murayama Takashi、Yamaguchi Maki、Oyamada Hideto、Suzuki Junji、Kurebayashi Nagomi、Kanemaru Kazunori、Oguchi Katsuji、Sakurai Takashi、Iino Masamitsu
    • Journal Title

      The Journal of General Physiology

      Volume: 152 Issue: 1 Pages: 0-0

    • DOI

      10.1085/jgp.201812235

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19H03404
  • [Journal Article] Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies2020

    • Author(s)
      Ogawa Haruo、Kurebayashi Nagomi、Yamazawa Toshiko、Murayama Takashi
    • Journal Title

      Journal of Muscle Research and Cell Motility

      Volume: in press Issue: 2 Pages: 0-0

    • DOI

      10.1007/s10974-020-09575-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-16H04748, KAKENHI-PROJECT-19H03404
  • [Journal Article] Design, synthesis and anti-malarial activities of synthetic analogs of biselyngbyolide B, a Ca 2+ pump inhibitor from marine cyanobacteria2018

    • Author(s)
      Sato Eisuke、Morita Maho、Ogawa Haruo、Iwatsuki Masato、Hokari Rei、Ishiyama Aki、?mura Satoshi、Iwasaki Arihiro、Suenaga Kiyotake
    • Journal Title

      Bioorganic and Medicinal Chemistry Letters

      Volume: 28 Issue: 3 Pages: 298-301

    • DOI

      10.1016/j.bmcl.2017.12.050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H03285, KAKENHI-PROJECT-17J03602, KAKENHI-PROJECT-16H04748
  • [Journal Article] Mechanism of the E2 to E1 transition in Ca2+ pump revealed by crystal structures of gating residue mutants.2018

    • Author(s)
      Naoki Tsunekawa, Haruo Ogawa, Junko Tsueda, Toshihiko Akiba, and Chikashi Toyoshima
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 115 Issue: 50 Pages: 12722-12727

    • DOI

      10.1073/pnas.1815472115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H02499
  • [Journal Article] Genotype-phenotype correlations of malignant hyperthermia and central core disease mutations in the central region of the RYR1 channel.2016

    • Author(s)
      Murayama, T., Kurebayashi, N., Ogawa, H., Yamazawa, T., Oyamada, H., Suzuki, J., Kanemaru, K., Oguchi, K., Iino, M. and Sakurai, T.
    • Journal Title

      Hum Mutat.

      Volume: 37 Issue: 11 Pages: 1231-1241

    • DOI

      10.1002/humu.23072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H04748
  • [Journal Article] Stimulation, inhibition or stabilization of Na, K-ATPase caused by specific lipid interactions at distinct sites2015

    • Author(s)
      M. Habeck, H. Haviv, A. Katz, E. Kapri-Pardes, S. Ayciriex, A. Shevchenko, H. Ogawa, C. Toyoshima, and S.J.D. Karlish
    • Journal Title

      J. Biol. Chem.

      Volume: 290 Issue: 8 Pages: 4829-4842

    • DOI

      10.1074/jbc.m114.611384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012
  • [Journal Article] Biselyngbyasides, Cytotoxic Marine Macrolides, are Novel and Potent Inhibitors of the Ca2+ Pumps with a Unique Mode of Binding2015

    • Author(s)
      Morita, M., Ogawa, H., Ohno, O., Yamori, T., Suenaga, K., Toyoshima, C.
    • Journal Title

      FEBS Lett.

      Volume: 589 Issue: 13 Pages: 1406-1411

    • DOI

      10.1016/j.febslet.2015.04.056

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
  • [Journal Article] Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle2015

    • Author(s)
      Zhao, Y., Ogawa, H., Yonekura, S., Mitsuhashi, H., Mitsuhashi, S., Nishino, I., Toyoshima, C., Ishiura, S.
    • Journal Title

      Biochim. Biophys. Acta.

      Volume: 1852 Issue: 10 Pages: 2042-2047

    • DOI

      10.1016/j.bbadis.2015.07.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
  • [Journal Article] Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography2015

    • Author(s)
      Ogawa, H., Cornelius, F., Hirata, A., Toyoshima, C.
    • Journal Title

      Nat Commun.

      Volume: 6 Issue: 1 Pages: 8004-8004

    • DOI

      10.1038/ncomms9004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
  • [Journal Article] ナトリウムポンプ蛋白質がナトリウムを選択的に運搬する機構 - How the Na+-pump recognizes and transports Na+ selectively.2015

    • Author(s)
      小川治夫, 金井隆太, 豊島近
    • Journal Title

      医学のあゆみ

      Volume: 254 Pages: 1186-1187

    • Data Source
      KAKENHI-PROJECT-25291012
  • [Journal Article] Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca^<2+>pumps with a unique mode of binding2015

    • Author(s)
      M. Morita, H. Ogawa, 0. Ohno, T. Yamori, K. Suenaga, C. Toyoshima
    • Journal Title

      FEBS Letters

    • Description
      【掲載確定】 印刷中
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Journal Article] ナトリウムポンプ蛋白質がナトリウムを選択的に運搬する機構 - How the Na+-pump recognizes and transports Na+ selectively.2015

    • Author(s)
      小川治夫, 金井隆太, 豊島近
    • Journal Title

      医学のあゆみ

      Volume: 254 Pages: 1186-1187

    • Data Source
      KAKENHI-PROJECT-25650020
  • [Journal Article] Crystal structures of the calcium pump and sarcolipin in the E1·Mg2+ state.2013

    • Author(s)
      C. Toyoshima
    • Journal Title

      Nature

      Volume: 495 Issue: 7440 Pages: 260-264

    • DOI

      10.1038/nature11899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020
  • [Journal Article] Crystal structure of a Na^+-bound Na^+, K^+-ATPase preceding the E1P state.2013

    • Author(s)
      R. Kanai, H. Ogawa, B. Vilsen, F. Cornelius and C. Toyoshima
    • Journal Title

      Nature

      Volume: 502 Issue: 7470 Pages: 201-206

    • DOI

      10.1038/nature12578

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020
  • [Journal Article] A new method for establishing stable cell lines and its use for large-scale production of human guanylyl cyclase-B receptor and of the extracellular domain2012

    • Author(s)
      Okamoto, N., Ogawa, H., Toyoshima, C.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 426 Issue: 2 Pages: 260-265

    • DOI

      10.1016/j.bbrc.2012.08.077

    • Data Source
      KAKENHI-PROJECT-22570110
  • [Journal Article] A newmethod for establishing stable cell linesand its use for large-scale production ofhuman guanylyl cyclase-B receptor and ofthe extracellular domain2012

    • Author(s)
      Okamoto, N., Ogawa, H., Toyoshima, C.
    • Journal Title

      Biochem. Biophys.Res. Commun.

      Volume: 426 Pages: 260-265

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570110
  • [Journal Article] Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase2011

    • Author(s)
      Misono, K.S., Philo, J.S., Arakawa, T., Ogata, C.M., Qiu, Y., Ogawa, H., Young, H.S.
    • Journal Title

      FEBS J

      Volume: (印刷中)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22570110
  • [Journal Article] Crystal tructure of the sodium-potassium pump (Na+, K+-ATPase)with bound potassium and ouabain.2009

    • Author(s)
      H. Ogawa, T. Shinoda, F. Cornelius, C. Toyoshima
    • Journal Title

      Proc. Nat. Acad. Sci. USA 106

      Pages: 13742-13747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] Crystal structure of the sodium-potassium pump at 2. 4 A resolution2009

    • Author(s)
      T. Shinoda, H. Ogawa, F. Cornelius and C. Toyoshima
    • Journal Title

      Nature

      Volume: 459 Pages: 446-450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] Crystal structure of the sodium-potassium pump at 2. 4 A resolution.2009

    • Author(s)
      T. Shinoda, H. Ogawa, F. Cornelius, C. Toyoshima
    • Journal Title

      Nature 459

      Pages: 446-450

    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] Crystal structure of thesodium-potassium pump(Na^+, K^+-ATPase) withbound potassium and ouabain2009

    • Author(s)
      H. Ogawa, T. Shinoda, F. Cornelius and C. Toyoshima
    • Journal Title

      Proc. Nat. Acad. Sci. USA

      Volume: 106 Pages: 13742-13747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] Crystal structure of the sodium-potassium pump(Na^+, K^+-ATPase)with bound potassium and ouabain2009

    • Author(s)
      H.Ogawa
    • Journal Title

      Proc.Nat.Acad.Sci.USA 106

      Pages: 13742-13747

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] How processing ofaspartylphosphate is coupled to lumenalgating of the ion pathway in the calciumpump2007

    • Author(s)
      C. Toyoshima, Y. Norimatsu, S. Iwasawa, T. Tsuda and H. Ogawa
    • Journal Title

      Proc. Nat. Acad. Sci.

      Volume: 104 Pages: 19831-19836

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19002013
  • [Journal Article] How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump.2007

    • Author(s)
      C. Toyoshima, Y. Norimatsu, S. Iwasawa, T. Tsuda, H. Ogawa
    • Journal Title

      Proc. Nat. Acad. Sci. USA. 104

      Pages: 19831-19836

    • Data Source
      KAKENHI-PROJECT-19002013
  • [Presentation] クライオ電子顕微鏡で広がる分子理解2023

    • Author(s)
      小川治夫
    • Organizer
      第65回日本平滑筋学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K27328
  • [Presentation] クライオ電顕による一膜貫通型受容体 NPR-Bの機能構造解析2023

    • Author(s)
      近藤瞳、児玉昌美、加藤博章、小川治夫
    • Organizer
      第44回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-22K19375
  • [Presentation] Cryo-EMによる立体構造から明らかになったGCase受容体の基質識別機構2023

    • Author(s)
      近藤瞳、児玉昌美、加藤博章、小川治夫
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Presentation] Elaborate gating mechanism of cardiac ryanodine receptor2023

    • Author(s)
      Ogawa Haruo
    • Organizer
      第101回生理学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K27328
  • [Presentation] 3D structure of RyR and SR Ca2+-ATPase responsible for muscle contraction and relaxation,2023

    • Author(s)
      Ogawa Haruo
    • Organizer
      Ion Channel Modulation Symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K27328
  • [Presentation] 心筋型リアノジン受容体のCa2+結合による開口機構2023

    • Author(s)
      小川治夫
    • Organizer
      日本薬学会143回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] Cryo-EMによる立体構造から明らかになったGCase受容体の基質識別機構2023

    • Author(s)
      近藤瞳、児玉昌美、加藤博章、小川治夫
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-22K19375
  • [Presentation] Elucidation of the gating mechanism by cryo-EM analysis2023

    • Author(s)
      Ogawa Haruo
    • Organizer
      生理研研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K27328
  • [Presentation] Structural basis for Ca2+-induced opening of cardiac ryanodine receptor2023

    • Author(s)
      小川治夫
    • Organizer
      日本生理学会 第100回記念大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] クライオ電顕による一回膜貫通型受容体NPR-Bの機能構造解析2023

    • Author(s)
      近藤瞳、児玉昌美、加藤博章、小川治夫
    • Organizer
      第44回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Presentation] Cryo-EMを用いた単粒子解析法によるhuman GC-B受容体細胞外ドメインの構造解析2022

    • Author(s)
      近藤 瞳、美濃 拓実、児玉 昌美、加藤 博章、小川 治夫
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Presentation] Gunanylate Cyclase受容体の基質識別機構の解析2022

    • Author(s)
      美濃 拓実、近藤 瞳、児玉 昌美、加藤 博章、小川 治夫
    • Organizer
      日本薬学会第142年会
    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Presentation] リアノジン受容体は「てこ」と「ドミノ倒し」で開口する2022

    • Author(s)
      小川治夫
    • Organizer
      日本生体エネルギー研究会 第48回討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] 心筋型リアノジン受容体のCa2+結合による開口の分子基盤2022

    • Author(s)
      小川治夫
    • Organizer
      第95回日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] 新規1型リアノジン受容体(RyR1)阻害剤の結合部位の同定.2021

    • Author(s)
      村山 尚、呉林 なごみ、小林 琢也、小川 治夫、児玉 昌美、森 修一、影近 弘之、櫻井 隆.
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] クライオ電子顕微鏡による心筋型リアノジン受容体loss-of-function変異体の解析2021

    • Author(s)
      小川治夫、小林琢也、包明久、呉林なごみ、斎藤慧、児玉昌美、櫻井隆、吉川雅英、村山尚
    • Organizer
      第94回日本生化学会
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] リアノジン受容体のカルシウムイオンによるゲーティング機構2021

    • Author(s)
      小川治夫
    • Organizer
      第7回日本筋学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02411
  • [Presentation] クライオ電子顕微鏡によるANP受容体細胞外ドメインの構造解析2021

    • Author(s)
      小川 治夫、美濃 拓実、近藤 瞳、児玉 昌美
    • Organizer
      第25回日本心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K06044
  • [Presentation] 新規1型リアノジン受容体(RyR1)阻害薬の結合部位の探索.2020

    • Author(s)
      村山 尚、呉林 なごみ、小林 琢也、小川 治夫、児玉 昌美、森 修一、影近 弘之、櫻井 隆.
    • Organizer
      第143回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-19H03404
  • [Presentation] Structural analysis of recombinant ryanodine receptors by cryo-EM2019

    • Author(s)
      Ogawa, H.
    • Organizer
      Gordon Research Conference, Muscle: Excitation-Contraction Coupling
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04748
  • [Presentation] 1.Molecular dynamics and Ca2+ imaging of mutant type 1 ryanodine receptors.2019

    • Author(s)
      Yamazawa T, Ogawa H, Murayama T, Yamaguchi M, Oyamada H, Suzuki J, Kurebayashi N, Kanemaru K, Oguchi K, Sakurai T, Iino M
    • Organizer
      Gordon Research Conference  Muscle: Excitation-Contraction Coupling
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07306
  • [Presentation] Crystal structures of SERCA2a and SERCA2b2018

    • Author(s)
      Ogawa, H., Kabashima, Y., Nakajima, R., Toyoshima, C.
    • Organizer
      Biophysical Society, 62nd Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04748
  • [Presentation] Recent advances in structural studies of SR Ca2+-ATPase2017

    • Author(s)
      小川治夫
    • Organizer
      第94回日本生理学会
    • Place of Presentation
      浜松アクトシティコングレスセンター(静岡県浜松市)
    • Year and Date
      2017-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Large production of mammalian membrane proteins toward determination of high-resolution structure2017

    • Author(s)
      Haruo Ogawa, Chikashi Toyoshima
    • Organizer
      Biophysical Society 61th annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04748
  • [Presentation] Structural analysis of P-type ATPase towards drug discovery2017

    • Author(s)
      Ogawa, H., Vilsen, B., Cornelius, F., Toyoshima, C.
    • Organizer
      ConBio2017(生命科学系合同年次大会)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04748
  • [Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017

    • Author(s)
      Haruo Ogawa, Chikashi Toyoshima
    • Organizer
      Biophysical Society 61st Annual Meeting
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2017-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017

    • Author(s)
      Haruo Ogawa, Chikashi Toyoshima
    • Organizer
      Biophysical Society 61st Annual Meeting
    • Place of Presentation
      New Orleans, Louisiana, USA
    • Year and Date
      2017-02-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Recent advances in structural studies of SR Ca2+-ATPase2017

    • Author(s)
      小川治夫
    • Organizer
      第94回日本生理学会
    • Place of Presentation
      浜松アクトシティコングレスセンター(静岡県浜松市)
    • Year and Date
      2017-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017

    • Author(s)
      Haruo Ogawa, Chikashi Toyoshima
    • Organizer
      Biophysical Society 61st Annual Meeting
    • Place of Presentation
      Ernest N. Morial Convention Center(米国ニューオーリンズ)
    • Year and Date
      2017-02-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016

    • Author(s)
      小川治夫、村山尚、呉林なごみ、豊島近
    • Organizer
      第89回 日本生化学会大会シンポジウム
    • Place of Presentation
      仙台国際センター/東北大学川内北キャンパス(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Kinetics by X-ray crystallography:sequential substitution of K+ bound to Na+,K+-ATPase2016

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      Biophysical Society 60th annual meeting
    • Place of Presentation
      Los Angeles Convention center, Los Angeles, California (USA)
    • Year and Date
      2016-02-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016

    • Author(s)
      小川治夫、村山尚、呉林なごみ、豊島近
    • Organizer
      第89回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H04748
  • [Presentation] Ca2+-ポンプ構造研究の最前線2016

    • Author(s)
      小川治夫、樺島佳樹、豊島近
    • Organizer
      日本生体エネルギー研究会 第42回討論会
    • Place of Presentation
      名古屋工業大学4号館ホール(愛知県名古屋市)
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Ca2+-ポンプ構造研究の最前線2016

    • Author(s)
      小川治夫、樺島佳樹、豊島近
    • Organizer
      日本生体エネルギー研究会 第42回討論会
    • Place of Presentation
      名古屋工業大学4号館ホール(愛知県名古屋市)
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016

    • Author(s)
      小川治夫、村山尚、呉林なごみ、豊島近
    • Organizer
      第89回 日本生化学会大会シンポジウム
    • Place of Presentation
      仙台国際センター/東北大学川内北キャンパス(宮城県仙台市)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016

    • Author(s)
      小川治夫、村山尚、呉林なごみ、豊島近
    • Organizer
      第89回 日本生化学会大会シンポジウム
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-09-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] Kinetics by X-ray crystallography:sequential substitution of K+ bound to Na+,K+-ATPase2016

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      Biophysical Society 60th annual meeting
    • Place of Presentation
      Los Angeles Convention center, Los Angeles, California (USA)
    • Year and Date
      2016-02-27
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Ca2+-ポンプ構造研究の最前線2016

    • Author(s)
      小川治夫、椛島佳樹、豊島近
    • Organizer
      日本生体エネルギー研究会第42回討論会
    • Place of Presentation
      名古屋工業大学4号館ホール(愛知県名古屋市)
    • Year and Date
      2016-12-20
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] Sequential substitution of bound K+ in the transmembrane binding sites of Na+,K+-ATPase, kinetics by X-ray crystallography.2015

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      日本生物物理学会第53回年会シンポジウム
    • Place of Presentation
      金沢大学 角間キャンパス自然科学本館(石川県・金沢市)
    • Year and Date
      2015-09-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Kinetics by X-ray crystallography: sequential substitution of K+ bound to Na+,K+-ATPase.2015

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      BMB2015(第38回日本分子生物学会 第88回日本生化学会合同大会)ワークショップ
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Kinetics by X-ray crystallography : sequential substitution of K^+ bound to Na^+, K^+-ATPase2015

    • Author(s)
      H. Ogawa, A. Hirata, F. Cornelius, C. Toyoshima
    • Organizer
      第38回日本分子生物学会 第88回日本生化学会合同大会(ワークショップオーガナイザー)
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-02
    • Description
      【発表確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] X線結晶構造解析によるキネティックス測定:Na+,K+-ATPaseに結合したK+は段階的に置換される2015

    • Author(s)
      小川治夫, 平田絢美, Flemming Cornelius, 豊島近
    • Organizer
      日本生体エネルギー研究会 第41回討論会
    • Place of Presentation
      東京大学医学部1号館講堂(東京都・文京区)
    • Year and Date
      2015-12-21
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] X線結晶構造解析によるキネティックス測定:Na+,K+-ATPaseに結合したK+は段階的に置換される2015

    • Author(s)
      小川治夫, 平田絢美, Flemming Cornelius, 豊島近
    • Organizer
      日本生体エネルギー研究会 第41回討論会
    • Place of Presentation
      東京大学医学部1号館講堂(東京都・文京区)
    • Year and Date
      2015-12-21
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Kinetics by X-ray crystallography: sequential substitution of K+ bound to Na+,K+-ATPase.2015

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      BMB2015(第38回日本分子生物学会 第88回日本生化学会合同大会)ワークショップ
    • Place of Presentation
      神戸ポートアイランド(兵庫県・神戸市)
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Sequential substitution of bound K^+ in the transmembrane binding sites of Na^+, K^+-ATPase : Kinetics by X-ray crystallography2015

    • Author(s)
      H. Ogawa, A. Hirata, F. Cornelius, C. Toyoshima
    • Organizer
      日本生物物理学会第53回年会シンポジウム「輸送膜タンパク質のダイナミクス」
    • Place of Presentation
      金沢大学(石川県金沢市)
    • Year and Date
      2015-09-15
    • Description
      【発行確定】
    • Invited
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] X線結晶構造解析によるキネティックス測定 : Na^+, K^+-ATPaseに結合したK^+は段階的に置換される2015

    • Author(s)
      小川 治夫
    • Organizer
      日本生体エネルギー研究会 第41回討論会
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2015-12-22
    • Description
      【発表確定】
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] Sequential substitution of bound K+ in the transmembrane binding sites of Na+,K+-ATPase, kinetics by X-ray crystallography.2015

    • Author(s)
      Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
    • Organizer
      日本生物物理学会第53回年会シンポジウム
    • Place of Presentation
      金沢大学 角間キャンパス自然科学本館(石川県・金沢市)
    • Year and Date
      2015-09-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] X-ray crystallographic study of Na, K-ATPase in complex with cardiotonic steroids2015

    • Author(s)
      H. Ogawa, et al.
    • Organizer
      Biophysical Society 59th Annual Meeting
    • Place of Presentation
      Baltimore Convension Center Baltimore, アメリカ
    • Year and Date
      2015-02-09
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] Na^+, K^+-ATPaseと強心配糖体複合体のX線結晶構造解析2014

    • Author(s)
      小川治夫
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013

    • Author(s)
      Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013

    • Author(s)
      Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013

    • Author(s)
      Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
    • Organizer
      The 2nd HD Physiology International Symposium
    • Place of Presentation
      丸の内 My Plaza Hall
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013

    • Author(s)
      Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
    • Organizer
      The 2nd HD Physiology International Symposium
    • Place of Presentation
      丸の内 My Plaza Hall
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013

    • Author(s)
      Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013

    • Author(s)
      Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
    • Organizer
      The 2nd HD Physiology International Symposium
    • Place of Presentation
      丸の内 My Plaza Hall
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] ANP受容体のホルモン認識機構2011

    • Author(s)
      小川治夫, 平田絢美, 杖田淳子, 豊島近
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-22570110
  • [Presentation] ANP 受容体のホルモン認識機構2011

    • Author(s)
      小川治夫, 平田絢美, 杖田淳子, 豊島近,
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-22570110
  • [Presentation] Sequential Substitution of Bound K^+ in the Transmembrane Binding Sites of Na^+, K^+-ATPase2011

    • Author(s)
      H.Ogawa
    • Organizer
      13TH INTERNATIONAL ATPase CONFERENCE Na, K-ATPase AND RELATED ATPases
    • Place of Presentation
      Pacific Grove, CA, USA
    • Year and Date
      2011-09-28
    • Data Source
      KAKENHI-PROJECT-23000014
  • [Presentation] ANP 受容体とホルモンとの複合体の X 線結晶構造解析 II2010

    • Author(s)
      小川治夫, 安田絵美, 平田絢美, 杖田淳子, 豊島近
    • Organizer
      BMB2010(第33回日本分子生物学会年会・第 83 回日本生化学会大会、合同大会)
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-22570110
  • [Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構

    • Author(s)
      森田 真布, 小川 治夫, 杖田 淳子, 大野 修, 矢守 隆夫, 豊島 近, 末永 聖武
    • Organizer
      日本化学会第95春季年会2015
    • Place of Presentation
      日本大学理工学部船橋キャンパス/薬学部(千葉県船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析

    • Author(s)
      小川 治夫, 元山 かん奈, Cornelius Flemming, Vilsen Bente, 豊島 近
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異

    • Author(s)
      趙 一夢, 小川 治夫, 米倉 慎一郎, 三橋 弘明, 豊島 近, 石浦 章一
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Large Production of SERCA toward determination of three-dimensional structures

    • Author(s)
      Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
    • Organizer
      ASMB special symposia series, Na,K-ATPase and related transport ATPases: Structure, Mechanism, Cell Biology, Health and Disease
    • Place of Presentation
      De Werelt Conference Centre, Lunteren, Netherlands
    • Year and Date
      2014-08-30 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異

    • Author(s)
      趙 一夢, 小川 治夫, 米倉 慎一郎, 三橋 弘明, 豊島 近, 石浦 章一
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Large Production of SERCA toward determination of three-dimensional structures

    • Author(s)
      Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
    • Organizer
      14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease
    • Place of Presentation
      De Werelt Conference Centre, Lunteren, Netherlands
    • Year and Date
      2014-08-30 – 2014-09-05
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids

    • Author(s)
      Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
    • Organizer
      Biophysical Society 59th Annual meeting
    • Place of Presentation
      Baltimore Convention Center, Baltimore, MD, USA
    • Year and Date
      2015-02-07 – 2015-02-11
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析

    • Author(s)
      小川 治夫, 元山 かん奈, Cornelius Flemming, Vilsen Bente, 豊島 近
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids

    • Author(s)
      Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
    • Organizer
      Biophysical Society 59th Annual meeting
    • Place of Presentation
      Baltimore Convention Center, Baltimore, MD, USA
    • Year and Date
      2015-02-07 – 2015-02-11
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • [Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構

    • Author(s)
      森田 真布, 小川 治夫, 杖田 淳子, 大野 修, 矢守 隆夫, 豊島 近, 末永 聖武
    • Organizer
      日本化学会第95春季年会2015
    • Place of Presentation
      日本大学理工学部船橋キャンパス/薬学部(千葉県船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25291012
  • [Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids

    • Author(s)
      Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
    • Organizer
      Biophysical Society 59th Annual meeting
    • Place of Presentation
      Baltimore Convention Center, Baltimore, MD, USA
    • Year and Date
      2015-02-07 – 2015-02-11
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析

    • Author(s)
      小川 治夫, 元山 かん奈, Cornelius Flemming, Vilsen Bente, 豊島 近
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] Large Production of SERCA toward determination of three-dimensional structures

    • Author(s)
      Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
    • Organizer
      14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease
    • Place of Presentation
      De Werelt Conference Centre, Lunteren, Netherlands
    • Year and Date
      2014-08-30 – 2014-09-05
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構

    • Author(s)
      森田 真布, 小川 治夫, 杖田 淳子, 大野 修, 矢守 隆夫, 豊島 近, 末永 聖武
    • Organizer
      日本化学会第95春季年会2015
    • Place of Presentation
      日本大学理工学部船橋キャンパス/薬学部(千葉県船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25650020
  • [Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異

    • Author(s)
      趙 一夢, 小川 治夫, 米倉 慎一郎, 三橋 弘明, 豊島 近, 石浦 章一
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PUBLICLY-25136702
  • 1.  TOYOSHIMA Chikashi (70172210)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 16 results
  • 2.  Murayama Takashi (10230012)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 7 results
  • 3.  呉林 なごみ (50133335)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  KANAI Ryuta (50598472)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 5.  小林 琢也 (60468585)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 6.  TSUDA Takeo (10345233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  MIMURA Hisatoshi (30463904)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KABASHIMA Yoshiki (00580573)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 9.  Kodama Masami (30512248)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 10.  冨田 拓郎 (60705060)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  杉原 匡美 (80648163)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KONDOU Youhei (30436604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  ISHIKITA Hiroshi (00508111)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  NAKASAKO Masayoshi (30227764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Yamazawa Toshio (00282616)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  井上 華 (20390700)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  石田 良典 (10937684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  加藤 博章 (90204487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  清水 啓史 (50324158)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  平井 義和 (40452271)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  萬谷 博 (20321870)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  加藤 龍一 (50240833)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  STOKES David L
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  Inesi Giuseppe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  Vilsen Bente
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 26.  Cornelius Flemming
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 27.  Karlish Steven
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 28.  KANEMARU Kazunori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  国広 なごみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 30.  末永 聖武
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  飯野 正光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  山口 啓介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  井関 雅子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  高橋 徳志子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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