Ogawa Haruo 小川治夫

… Alternative Names

OGAWA Haruo 小川治夫

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Researcher Number	40292726
Other IDs
External Links
Affiliation (Current)	2025: 京都大学, 薬学研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 薬学研究科, 准教授 2017 – 2021: 東京大学, 定量生命科学研究所, 准教授 2007 – 2016: 東京大学, 分子細胞生物学研究所, 准教授 2002: 東大, 分子細胞生物学研究所, 助手 2001: The University of Tokyo, Institute of Molecular and Cellular Biosciences, Research associate, 分子細胞生物学研究所, 助手 … More 1999: 東京大学, 分子細胞生物学研究所, 助手 1997 – 1998: The University of Tokyo, Faculty of Medicine, Research Associate, 大学院・医学系研究科, 助手 1997: 東京大学, 大学院医学系研究科, 助手 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Biophysics / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 43020:Structural biochemistry-related / Complex systems Except Principal Investigator Basic Section 48020:Physiology-related / Biophysics / Biological Sciences / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related … More / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Basic Section 47040:Pharmacology-related / Basic Section 43020:Structural biochemistry-related / Biophysics / Biological Sciences Less
Keywords	Principal Investigator 膜蛋白質 / イオンポンプ蛋白質 / X線結晶解析 / X線結晶構造解析 / クライオ電子顕微鏡 / リアノジン受容体 / 大量発現 / 膜１回貫通型受容体 / 立体構造解析 / 膜タンパク質 … More / 構造解析 / イオンチャネル / カルシウムチャネル / イオンポンプタンパク質 / 超巨大蛋白質 / アデノウィルス / 心収縮 / 膜受容体 / ホルモン / ANP / 受容体 / x-ray crystallography / active transport / ion pump / P-type ATPase / バキュロウィルス / SF9 / 界面活性剤 / 二次元結晶 / アセチルコリン受容体 … More Except Principal Investigator イオンポンプ / 膜蛋白質 / 骨格筋 / リアノジン受容体 / 結晶解析 / ATPase / 能動輸送 / クライオ電子顕微鏡 / カルシウムイオン / 創薬 / 筋小胞体 / 興奮収縮連関 / カルシウムチャネル / カルシウム / 悪性高熱症 / 蛋白質 / 構造生物学 / membrane proteins / active transport / ion pump / 構造解析 / エネルギー変換 / 電子線結晶解析 / X線結晶解析 / 蛋白質結晶 / 糖転移酵素 / O-マンノース型糖鎖 / 神経疾患 / 筋疾患 / 糖鎖 / X線回折 / 1分子計測 / カルシウム遊離チャネル / 筋収縮 / 構造薬理学 / 輸送体 / 分子認識 / 心筋 / 機能抑制型変異 / 抗不整脈薬 / 不整脈 / 2型リアノジン受容体 / GCase受容体 / グアニル酸シクラーゼ受容体 / ナトリウム利尿ペプチド / GC受容体 / イオンチャネル / 機能解析 / サブタイプ / 小胞体 / 分子動力学計算 / リアノジン / 熱 / Ca2+放出 / 生物物理 / X-ray crystallography / electron crystallography / Protein crystals / structural analysis / electron microscopy / three-dimensional structure / calcium pump / 電子顕微鏡 / 三次元構造 / カルシウムポンプ / エネルギー交換 / 脂質二重膜 Less

Structural basis of diversed and dynamic substrate recognition mechanism of multidrug transporter by chemical trapping
- Principal Investigator
  
  加藤博章
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto University
創薬へ向けた心筋型リアノジン受容体の活性制御機構の構造的解明Principal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
X線1分子動態計測による膜蛋白質マルチセンシング機構の動的解明
- Principal Investigator
  
  清水啓史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  University of Fukui
Molecular basis and physiological significance of O-mannosyl glycans in mammals
- Principal Investigator
  
  萬谷博
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Development of RyR2-specific inhibitors and activators and their application as antiarrhythmic agents
- Principal Investigator
  
  呉林なごみ
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Juntendo University
膜1回貫通型受容体を対象にした「構造生物学での最後のフロンティア」解消への挑戦Principal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Elucidation of molecular mechanism for depolarization-induced Ca2+ release using novel reconstitution system
- Principal Investigator
  
  村山尚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
Structural biology of GC-A receptor - Mechanism underlying peptide recognition and intramolecular signal transduction
- Principal Investigator
  
  Kodama Masami
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  University of Shizuoka
  Juntendo University
Structural analysis of the gating mechanism of cardiac ryanodine receptorPrincipal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto University
Analysis of a novel ryanodine receptor modulation mechanism using physiological experiments and molecular dynamics calculations
- Principal Investigator
  
  Yamazawa Toshio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Jikei University School of Medicine
Molecular basis of subtype-specific channel regulation using novel ryanodine receptor modulators
- Principal Investigator
  
  Murayama Takashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Juntendo University
Structural elucidation of active transport by P-type ATPases
- Principal Investigator
  
  Toyoshima Chikashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Elucidation of tissue-specific calcium ion regulation mechanism by calcium pump by crystallographyPrincipal Investigator
- Principal Investigator
  
  Ogawa Haruo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
PLN/SERCA2aレギュラトームによる心収縮調節機構の解明Principal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Structural analysis of PLN/SERCA regulatome toward understanding of the mechanism of Ca2+-regulation in the cardiac muscle cellsPrincipal Investigator
- Principal Investigator
  
  Ogawa Haruo
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Establishment of an over-expression system for mammalian large membrane proteinsPrincipal Investigator
- Principal Investigator
  
  Ogawa Haruo
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Structural biology of membrane transporters with a view to drug development
- Principal Investigator
  
  TOYOSHIMA Chikashi
- Project Period (FY)
  2011 – 2016
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Structure and functional analysis of the GCase receptor by x-rayPrincipal Investigator
- Principal Investigator
  
  OGAWA Haruo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
Structural biology of ion transporters
- Principal Investigator
  
  TOYOSHIMA Chikashi
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
イオン能動輸送のメカニズム解明へ向けた立体構造解析Principal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Ca-ATPaseの電子線・X線結晶解析
- Principal Investigator
  
  TOYOSHIMA Chikashi
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Crystallographics study of active ion transport
- Principal Investigator
  
  TOYOSHIMA Chikashi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
ムスカリン性アセチルコリン受容体の2次元結晶化Principal Investigator
- Principal Investigator
  
  小川治夫
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo
Structural Basis of Active Transport by Ion Pumps
- Principal Investigator
  
  TOYOSHIMA Chikashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Biophysics
- Research Institution
  The University of Tokyo

[Journal Article] Structural insight into hormone recognition by the natriuretic peptide receptor-A2024
- Author(s)
  Haruo Ogawa, Masami Kodama
- Journal Title
  
  The FEBS Journal
  
  Volume: 04 March 2024 Issue: 10 Pages: 114-114
- DOI
  10.1111/febs.17104
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19375, KAKENHI-PROJECT-21K06044
[Journal Article] Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations2022
- Author(s)
  Kobayashi Takuya、Tsutsumi Akihisa、Kurebayashi Nagomi、Saito Kei、Kodama Masami、Sakurai Takashi、Kikkawa Masahide、Murayama Takashi、Ogawa Haruo
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2821-2821
- DOI
  10.1038/s41467-022-30429-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21H02411, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K24067
[Journal Article] ナトリウム利尿ペプチド受容体の基質認識とその活性化機構2021
- Author(s)
  小川　治夫、児玉　昌美
- Journal Title
  
  循環器内科
  
  Volume: 89 Pages: 454-462
- NAID
  40022569004
- Data Source
  KAKENHI-PROJECT-21K06044
[Journal Article] Sudden death after inappropriate shocks of implantable cardioverter defibrillator in a catecholaminergic polymorphic ventricular tachycardia case with a novel RyR2 mutation2021
- Author(s)
  Itoh Hideki、Murayama Takashi、Kurebayashi Nagomi、Ohno Seiko、Kobayashi Takuya、Fujii Yusuke、Watanabe Masaya、Ogawa Haruo、Anzai Toshihisa、Horie Minoru
- Journal Title
  
  Journal of Electrocardiology
  
  Volume: 69 Pages: 111-118
- DOI
  10.1016/j.jelectrocard.2021.09.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K08473, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-21H02411
[Journal Article] Inhibition of endothelin A receptor by a novel, selective receptor antagonist enhances morphine-induced analgesia: Possible functional interaction of dimerized endothelin A and μ-opioid receptors. Biomed Pharmacother.2021
- Author(s)
  Kuroda Y, Nonaka M, Kamikubo Y, Ogawa H, Murayama T, Kurebayashi N, Sakairi H, Miyano K, Komatsu A, Dodo T, Nakano-Ito K, Yamaguchi K, Sakurai T, Iseki M, Hayashida M, Uezono Y
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 141 Pages: 111800-111800
- DOI
  10.1016/j.biopha.2021.111800
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08866, KAKENHI-PROJECT-19K16497, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-20K07765, KAKENHI-PROJECT-21K06584, KAKENHI-PROJECT-20K22745, KAKENHI-PROJECT-19H03404
[Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020
- Author(s)
  Yamazawa Toshiko、Ogawa Haruo、Murayama Takashi、Yamaguchi Maki、Oyamada Hideto、Suzuki Junji、Kurebayashi Nagomi、Kanemaru Kazunori、Oguchi Katsuji、Sakurai Takashi、Iino Masamitsu
- Journal Title
  
  The Journal of General Physiology
  
  Volume: 152 Issue: 1 Pages: 0-0
- DOI
  10.1085/jgp.201812235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19H03404
[Journal Article] Regulatory mechanisms of ryanodine receptor/Ca2+ release channel revealed by recent advancements in structural studies2020
- Author(s)
  Ogawa Haruo、Kurebayashi Nagomi、Yamazawa Toshiko、Murayama Takashi
- Journal Title
  
  Journal of Muscle Research and Cell Motility
  
  Volume: in press Issue: 2 Pages: 0-0
- DOI
  10.1007/s10974-020-09575-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-16H04748, KAKENHI-PROJECT-19H03404
[Journal Article] Design, synthesis and anti-malarial activities of synthetic analogs of biselyngbyolide B, a Ca 2+ pump inhibitor from marine cyanobacteria2018
- Author(s)
  Sato Eisuke、Morita Maho、Ogawa Haruo、Iwatsuki Masato、Hokari Rei、Ishiyama Aki、?mura Satoshi、Iwasaki Arihiro、Suenaga Kiyotake
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 28 Issue: 3 Pages: 298-301
- DOI
  10.1016/j.bmcl.2017.12.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03285, KAKENHI-PROJECT-17J03602, KAKENHI-PROJECT-16H04748
[Journal Article] Mechanism of the E2 to E1 transition in Ca2+ pump revealed by crystal structures of gating residue mutants.2018
- Author(s)
  Naoki Tsunekawa, Haruo Ogawa, Junko Tsueda, Toshihiko Akiba, and Chikashi Toyoshima
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 50 Pages: 12722-12727
- DOI
  10.1073/pnas.1815472115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02499
[Journal Article] Genotype-phenotype correlations of malignant hyperthermia and central core disease mutations in the central region of the RYR1 channel.2016
- Author(s)
  Murayama, T., Kurebayashi, N., Ogawa, H., Yamazawa, T., Oyamada, H., Suzuki, J., Kanemaru, K., Oguchi, K., Iino, M. and Sakurai, T.
- Journal Title
  
  Hum Mutat.
  
  Volume: 37 Issue: 11 Pages: 1231-1241
- DOI
  10.1002/humu.23072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-15H05648, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-15K08243, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-16H04748
[Journal Article] Stimulation, inhibition or stabilization of Na, K-ATPase caused by specific lipid interactions at distinct sites2015
- Author(s)
  M. Habeck, H. Haviv, A. Katz, E. Kapri-Pardes, S. Ayciriex, A. Shevchenko, H. Ogawa, C. Toyoshima, and S.J.D. Karlish
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Issue: 8 Pages: 4829-4842
- DOI
  10.1074/jbc.m114.611384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012
[Journal Article] Biselyngbyasides, Cytotoxic Marine Macrolides, are Novel and Potent Inhibitors of the Ca2+ Pumps with a Unique Mode of Binding2015
- Author(s)
  Morita, M., Ogawa, H., Ohno, O., Yamori, T., Suenaga, K., Toyoshima, C.
- Journal Title
  
  FEBS Lett.
  
  Volume: 589 Issue: 13 Pages: 1406-1411
- DOI
  10.1016/j.febslet.2015.04.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
[Journal Article] Functional analysis of SERCA1b, a highly expressed SERCA1 variant in myotonic dystrophy type 1 muscle2015
- Author(s)
  Zhao, Y., Ogawa, H., Yonekura, S., Mitsuhashi, H., Mitsuhashi, S., Nishino, I., Toyoshima, C., Ishiura, S.
- Journal Title
  
  Biochim. Biophys. Acta.
  
  Volume: 1852 Issue: 10 Pages: 2042-2047
- DOI
  10.1016/j.bbadis.2015.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
[Journal Article] Sequential substitution of K+ bound to Na+,K+-ATPase visualized by X-ray crystallography2015
- Author(s)
  Ogawa, H., Cornelius, F., Hirata, A., Toyoshima, C.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 8004-8004
- DOI
  10.1038/ncomms9004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25650020, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-23000014
[Journal Article] ナトリウムポンプ蛋白質がナトリウムを選択的に運搬する機構 - How the Na+-pump recognizes and transports Na+ selectively.2015
- Author(s)
  小川治夫, 金井隆太, 豊島近
- Journal Title
  
  医学のあゆみ
  
  Volume: 254 Pages: 1186-1187
- Data Source
  KAKENHI-PROJECT-25291012
[Journal Article] Biselyngbyasides, cytotoxic marine macrolides, are novel and potent inhibitors of the Ca^<2+>pumps with a unique mode of binding2015
- Author(s)
  M. Morita, H. Ogawa, 0. Ohno, T. Yamori, K. Suenaga, C. Toyoshima
- Journal Title
  
  FEBS Letters
- Description
  【掲載確定】印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000014
[Journal Article] ナトリウムポンプ蛋白質がナトリウムを選択的に運搬する機構 - How the Na+-pump recognizes and transports Na+ selectively.2015
- Author(s)
  小川治夫, 金井隆太, 豊島近
- Journal Title
  
  医学のあゆみ
  
  Volume: 254 Pages: 1186-1187
- Data Source
  KAKENHI-PROJECT-25650020
[Journal Article] Crystal structures of the calcium pump and sarcolipin in the E1·Mg2+ state.2013
- Author(s)
  C. Toyoshima
- Journal Title
  
  Nature
  
  Volume: 495 Issue: 7440 Pages: 260-264
- DOI
  10.1038/nature11899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020
[Journal Article] Crystal structure of a Na^+-bound Na^+, K^+-ATPase preceding the E1P state.2013
- Author(s)
  R. Kanai, H. Ogawa, B. Vilsen, F. Cornelius and C. Toyoshima
- Journal Title
  
  Nature
  
  Volume: 502 Issue: 7470 Pages: 201-206
- DOI
  10.1038/nature12578
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23000014, KAKENHI-PUBLICLY-25136702, KAKENHI-PROJECT-25291012, KAKENHI-PROJECT-25650020
[Journal Article] A new method for establishing stable cell lines and its use for large-scale production of human guanylyl cyclase-B receptor and of the extracellular domain2012
- Author(s)
  Okamoto, N., Ogawa, H., Toyoshima, C.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 426 Issue: 2 Pages: 260-265
- DOI
  10.1016/j.bbrc.2012.08.077
- Data Source
  KAKENHI-PROJECT-22570110
[Journal Article] A newmethod for establishing stable cell linesand its use for large-scale production ofhuman guanylyl cyclase-B receptor and ofthe extracellular domain2012
- Author(s)
  Okamoto, N., Ogawa, H., Toyoshima, C.
- Journal Title
  
  Biochem. Biophys.Res. Commun.
  
  Volume: 426 Pages: 260-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570110
[Journal Article] Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase2011
- Author(s)
  Misono, K.S., Philo, J.S., Arakawa, T., Ogata, C.M., Qiu, Y., Ogawa, H., Young, H.S.
- Journal Title
  
  FEBS J
  
  Volume: (印刷中)(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570110
[Journal Article] Crystal tructure of the sodium-potassium pump (Na+, K+-ATPase)with bound potassium and ouabain.2009
- Author(s)
  H. Ogawa, T. Shinoda, F. Cornelius, C. Toyoshima
- Journal Title
  
  Proc. Nat. Acad. Sci. USA 106
  
  Pages: 13742-13747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] Crystal structure of the sodium-potassium pump at 2. 4 A resolution2009
- Author(s)
  T. Shinoda, H. Ogawa, F. Cornelius and C. Toyoshima
- Journal Title
  
  Nature
  
  Volume: 459 Pages: 446-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] Crystal structure of the sodium-potassium pump at 2. 4 A resolution.2009
- Author(s)
  T. Shinoda, H. Ogawa, F. Cornelius, C. Toyoshima
- Journal Title
  
  Nature 459
  
  Pages: 446-450
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] Crystal structure of thesodium-potassium pump(Na^+, K^+-ATPase) withbound potassium and ouabain2009
- Author(s)
  H. Ogawa, T. Shinoda, F. Cornelius and C. Toyoshima
- Journal Title
  
  Proc. Nat. Acad. Sci. USA
  
  Volume: 106 Pages: 13742-13747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] Crystal structure of the sodium-potassium pump(Na^+, K^+-ATPase)with bound potassium and ouabain2009
- Author(s)
  H.Ogawa
- Journal Title
  
  Proc.Nat.Acad.Sci.USA 106
  
  Pages: 13742-13747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] How processing ofaspartylphosphate is coupled to lumenalgating of the ion pathway in the calciumpump2007
- Author(s)
  C. Toyoshima, Y. Norimatsu, S. Iwasawa, T. Tsuda and H. Ogawa
- Journal Title
  
  Proc. Nat. Acad. Sci.
  
  Volume: 104 Pages: 19831-19836
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19002013
[Journal Article] How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump.2007
- Author(s)
  C. Toyoshima, Y. Norimatsu, S. Iwasawa, T. Tsuda, H. Ogawa
- Journal Title
  
  Proc. Nat. Acad. Sci. USA. 104
  
  Pages: 19831-19836
- Data Source
  KAKENHI-PROJECT-19002013
[Presentation] クライオ電子顕微鏡で広がる分子理解2023
- Author(s)
  小川治夫
- Organizer
  第65回日本平滑筋学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] クライオ電顕による一膜貫通型受容体 NPR-Bの機能構造解析2023
- Author(s)
  近藤瞳、児玉昌美、加藤博章、小川治夫
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-22K19375
[Presentation] Cryo-EMによる立体構造から明らかになったGCase受容体の基質識別機構2023
- Author(s)
  近藤瞳、児玉昌美、加藤博章、小川治夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06044
[Presentation] Elaborate gating mechanism of cardiac ryanodine receptor2023
- Author(s)
  Ogawa Haruo
- Organizer
  第101回生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] 3D structure of RyR and SR Ca2+-ATPase responsible for muscle contraction and relaxation,2023
- Author(s)
  Ogawa Haruo
- Organizer
  Ion Channel Modulation Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] 心筋型リアノジン受容体のCa2+結合による開口機構2023
- Author(s)
  小川治夫
- Organizer
  日本薬学会143回年会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] Cryo-EMによる立体構造から明らかになったGCase受容体の基質識別機構2023
- Author(s)
  近藤瞳、児玉昌美、加藤博章、小川治夫
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K19375
[Presentation] Elucidation of the gating mechanism by cryo-EM analysis2023
- Author(s)
  Ogawa Haruo
- Organizer
  生理研研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27328
[Presentation] Structural basis for Ca2+-induced opening of cardiac ryanodine receptor2023
- Author(s)
  小川治夫
- Organizer
  日本生理学会第100回記念大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] クライオ電顕による一回膜貫通型受容体NPR-Bの機能構造解析2023
- Author(s)
  近藤瞳、児玉昌美、加藤博章、小川治夫
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06044
[Presentation] Cryo-EMを用いた単粒子解析法によるhuman GC-B受容体細胞外ドメインの構造解析2022
- Author(s)
  近藤　瞳、美濃　拓実、児玉　昌美、加藤　博章、小川　治夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06044
[Presentation] Gunanylate Cyclase受容体の基質識別機構の解析2022
- Author(s)
  美濃　拓実、近藤　瞳、児玉　昌美、加藤　博章、小川　治夫
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06044
[Presentation] リアノジン受容体は「てこ」と「ドミノ倒し」で開口する2022
- Author(s)
  小川治夫
- Organizer
  日本生体エネルギー研究会　第48回討論会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] 心筋型リアノジン受容体のCa2+結合による開口の分子基盤2022
- Author(s)
  小川治夫
- Organizer
  第95回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] 新規1型リアノジン受容体（RyR1）阻害剤の結合部位の同定．2021
- Author(s)
  村山尚、呉林なごみ、小林琢也、小川治夫、児玉昌美、森修一、影近弘之、櫻井隆．
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] クライオ電子顕微鏡による心筋型リアノジン受容体loss-of-function変異体の解析2021
- Author(s)
  小川治夫、小林琢也、包明久、呉林なごみ、斎藤慧、児玉昌美、櫻井隆、吉川雅英、村山尚
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] リアノジン受容体のカルシウムイオンによるゲーティング機構2021
- Author(s)
  小川治夫
- Organizer
  第7回日本筋学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02411
[Presentation] クライオ電子顕微鏡によるANP受容体細胞外ドメインの構造解析2021
- Author(s)
  小川　治夫、美濃　拓実、近藤　瞳、児玉　昌美
- Organizer
  第25回日本心血管内分泌代謝学会学術総会
- Data Source
  KAKENHI-PROJECT-21K06044
[Presentation] 新規1型リアノジン受容体（RyR1）阻害薬の結合部位の探索．2020
- Author(s)
  村山尚、呉林なごみ、小林琢也、小川治夫、児玉昌美、森修一、影近弘之、櫻井隆．
- Organizer
  第143回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19H03404
[Presentation] Structural analysis of recombinant ryanodine receptors by cryo-EM2019
- Author(s)
  Ogawa, H.
- Organizer
  Gordon Research Conference, Muscle: Excitation-Contraction Coupling
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04748
[Presentation] 1.Molecular dynamics and Ca2+ imaging of mutant type 1 ryanodine receptors.2019
- Author(s)
  Yamazawa T, Ogawa H, Murayama T, Yamaguchi M, Oyamada H, Suzuki J, Kurebayashi N, Kanemaru K, Oguchi K, Sakurai T, Iino M
- Organizer
  Gordon Research Conference　 Muscle: Excitation-Contraction Coupling
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07306
[Presentation] Crystal structures of SERCA2a and SERCA2b2018
- Author(s)
  Ogawa, H., Kabashima, Y., Nakajima, R., Toyoshima, C.
- Organizer
  Biophysical Society, 62nd Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04748
[Presentation] Recent advances in structural studies of SR Ca2+-ATPase2017
- Author(s)
  小川治夫
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松アクトシティコングレスセンター（静岡県浜松市）
- Year and Date
  2017-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Large production of mammalian membrane proteins toward determination of high-resolution structure2017
- Author(s)
  Haruo Ogawa, Chikashi Toyoshima
- Organizer
  Biophysical Society 61th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04748
[Presentation] Structural analysis of P-type ATPase towards drug discovery2017
- Author(s)
  Ogawa, H., Vilsen, B., Cornelius, F., Toyoshima, C.
- Organizer
  ConBio2017（生命科学系合同年次大会）
- Invited
- Data Source
  KAKENHI-PROJECT-16H04748
[Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017
- Author(s)
  Haruo Ogawa, Chikashi Toyoshima
- Organizer
  Biophysical Society 61st Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017
- Author(s)
  Haruo Ogawa, Chikashi Toyoshima
- Organizer
  Biophysical Society 61st Annual Meeting
- Place of Presentation
  New Orleans, Louisiana, USA
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Recent advances in structural studies of SR Ca2+-ATPase2017
- Author(s)
  小川治夫
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松アクトシティコングレスセンター（静岡県浜松市）
- Year and Date
  2017-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Large-scale production of mammalian membrane proteins toward determination of high resolution structures2017
- Author(s)
  Haruo Ogawa, Chikashi Toyoshima
- Organizer
  Biophysical Society 61st Annual Meeting
- Place of Presentation
  Ernest N. Morial Convention Center(米国ニューオーリンズ)
- Year and Date
  2017-02-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016
- Author(s)
  小川治夫、村山尚、呉林なごみ、豊島近
- Organizer
  第89回　日本生化学会大会シンポジウム
- Place of Presentation
  仙台国際センター/東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Kinetics by X-ray crystallography:sequential substitution of K+ bound to Na+,K+-ATPase2016
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  Biophysical Society 60th annual meeting
- Place of Presentation
  Los Angeles Convention center, Los Angeles, California (USA)
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016
- Author(s)
  小川治夫、村山尚、呉林なごみ、豊島近
- Organizer
  第89回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04748
[Presentation] Ca2+-ポンプ構造研究の最前線2016
- Author(s)
  小川治夫、樺島佳樹、豊島近
- Organizer
  日本生体エネルギー研究会第42回討論会
- Place of Presentation
  名古屋工業大学4号館ホール（愛知県名古屋市）
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Ca2+-ポンプ構造研究の最前線2016
- Author(s)
  小川治夫、樺島佳樹、豊島近
- Organizer
  日本生体エネルギー研究会第42回討論会
- Place of Presentation
  名古屋工業大学4号館ホール（愛知県名古屋市）
- Year and Date
  2016-12-19
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016
- Author(s)
  小川治夫、村山尚、呉林なごみ、豊島近
- Organizer
  第89回　日本生化学会大会シンポジウム
- Place of Presentation
  仙台国際センター/東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] 高分解能構造解析へ向けた哺乳類由来膜蛋白質の大量生産2016
- Author(s)
  小川治夫、村山尚、呉林なごみ、豊島近
- Organizer
  第89回日本生化学会大会シンポジウム
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] Kinetics by X-ray crystallography:sequential substitution of K+ bound to Na+,K+-ATPase2016
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  Biophysical Society 60th annual meeting
- Place of Presentation
  Los Angeles Convention center, Los Angeles, California (USA)
- Year and Date
  2016-02-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Ca2+-ポンプ構造研究の最前線2016
- Author(s)
  小川治夫、椛島佳樹、豊島近
- Organizer
  日本生体エネルギー研究会第42回討論会
- Place of Presentation
  名古屋工業大学4号館ホール(愛知県名古屋市)
- Year and Date
  2016-12-20
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] Sequential substitution of bound K+ in the transmembrane binding sites of Na+,K+-ATPase, kinetics by X-ray crystallography.2015
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  日本生物物理学会第53回年会シンポジウム
- Place of Presentation
  金沢大学　角間キャンパス自然科学本館（石川県・金沢市）
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Kinetics by X-ray crystallography: sequential substitution of K+ bound to Na+,K+-ATPase.2015
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  BMB2015（第38回日本分子生物学会　第88回日本生化学会合同大会）ワークショップ
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Kinetics by X-ray crystallography : sequential substitution of K^+ bound to Na^+, K^+-ATPase2015
- Author(s)
  H. Ogawa, A. Hirata, F. Cornelius, C. Toyoshima
- Organizer
  第38回日本分子生物学会第88回日本生化学会合同大会(ワークショップオーガナイザー)
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-02
- Description
  【発表確定】
- Invited
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] X線結晶構造解析によるキネティックス測定：Na+,K+-ATPaseに結合したK+は段階的に置換される2015
- Author(s)
  小川治夫, 平田絢美, Flemming Cornelius, 豊島近
- Organizer
  日本生体エネルギー研究会　第41回討論会
- Place of Presentation
  東京大学医学部１号館講堂（東京都・文京区）
- Year and Date
  2015-12-21
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] X線結晶構造解析によるキネティックス測定：Na+,K+-ATPaseに結合したK+は段階的に置換される2015
- Author(s)
  小川治夫, 平田絢美, Flemming Cornelius, 豊島近
- Organizer
  日本生体エネルギー研究会　第41回討論会
- Place of Presentation
  東京大学医学部１号館講堂（東京都・文京区）
- Year and Date
  2015-12-21
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Kinetics by X-ray crystallography: sequential substitution of K+ bound to Na+,K+-ATPase.2015
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  BMB2015（第38回日本分子生物学会　第88回日本生化学会合同大会）ワークショップ
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Sequential substitution of bound K^+ in the transmembrane binding sites of Na^+, K^+-ATPase : Kinetics by X-ray crystallography2015
- Author(s)
  H. Ogawa, A. Hirata, F. Cornelius, C. Toyoshima
- Organizer
  日本生物物理学会第53回年会シンポジウム「輸送膜タンパク質のダイナミクス」
- Place of Presentation
  金沢大学(石川県金沢市)
- Year and Date
  2015-09-15
- Description
  【発行確定】
- Invited
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] X線結晶構造解析によるキネティックス測定 : Na^+, K^+-ATPaseに結合したK^+は段階的に置換される2015
- Author(s)
  小川治夫
- Organizer
  日本生体エネルギー研究会第41回討論会
- Place of Presentation
  東京大学(東京都文京区)
- Year and Date
  2015-12-22
- Description
  【発表確定】
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] Sequential substitution of bound K+ in the transmembrane binding sites of Na+,K+-ATPase, kinetics by X-ray crystallography.2015
- Author(s)
  Haruo Ogawa, Flemming Cornelius,Ayami Hirata, Chikashi Toyoshima
- Organizer
  日本生物物理学会第53回年会シンポジウム
- Place of Presentation
  金沢大学　角間キャンパス自然科学本館（石川県・金沢市）
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] X-ray crystallographic study of Na, K-ATPase in complex with cardiotonic steroids2015
- Author(s)
  H. Ogawa, et al.
- Organizer
  Biophysical Society 59th Annual Meeting
- Place of Presentation
  Baltimore Convension Center Baltimore, アメリカ
- Year and Date
  2015-02-09
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] Na^+, K^+-ATPaseと強心配糖体複合体のX線結晶構造解析2014
- Author(s)
  小川治夫
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府京都市)
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013
- Author(s)
  Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013
- Author(s)
  Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013
- Author(s)
  Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
- Organizer
  The 2nd HD Physiology International Symposium
- Place of Presentation
  丸の内 My Plaza Hall
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013
- Author(s)
  Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
- Organizer
  The 2nd HD Physiology International Symposium
- Place of Presentation
  丸の内 My Plaza Hall
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Extensive analysis on the interaction between sarcolipin and Ca2+-ATPase2013
- Author(s)
  Ogawa, H., Iwasawa, S., Hirata, A., Tsueda, J., Toyoshima, C.
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Large production of mammalian membrane proteins toward determination of three-dimensional structures2013
- Author(s)
  Ogawa, H., Hirata, A., Tsueda, J., Inesi, G., Toyoshima, C.
- Organizer
  The 2nd HD Physiology International Symposium
- Place of Presentation
  丸の内 My Plaza Hall
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] ANP受容体のホルモン認識機構2011
- Author(s)
  小川治夫, 平田絢美, 杖田淳子, 豊島近
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22570110
[Presentation] ANP 受容体のホルモン認識機構2011
- Author(s)
  小川治夫, 平田絢美, 杖田淳子, 豊島近,
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-22570110
[Presentation] Sequential Substitution of Bound K^+ in the Transmembrane Binding Sites of Na^+, K^+-ATPase2011
- Author(s)
  H.Ogawa
- Organizer
  13TH INTERNATIONAL ATPase CONFERENCE Na, K-ATPase AND RELATED ATPases
- Place of Presentation
  Pacific Grove, CA, USA
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-23000014
[Presentation] ANP 受容体とホルモンとの複合体の X 線結晶構造解析 II2010
- Author(s)
  小川治夫, 安田絵美, 平田絢美, 杖田淳子, 豊島近
- Organizer
  BMB2010(第33回日本分子生物学会年会・第 83 回日本生化学会大会、合同大会)
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-22570110
[Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構
- Author(s)
  森田真布, 小川治夫, 杖田淳子, 大野修, 矢守隆夫, 豊島近, 末永聖武
- Organizer
  日本化学会第95春季年会2015
- Place of Presentation
  日本大学理工学部船橋キャンパス/薬学部（千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析
- Author(s)
  小川治夫, 元山かん奈, Cornelius Flemming, Vilsen Bente, 豊島近
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異
- Author(s)
  趙一夢, 小川治夫, 米倉慎一郎, 三橋弘明, 豊島近, 石浦章一
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Large Production of SERCA toward determination of three-dimensional structures
- Author(s)
  Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
- Organizer
  ASMB special symposia series, Na,K-ATPase and related transport ATPases: Structure, Mechanism, Cell Biology, Health and Disease
- Place of Presentation
  De Werelt Conference Centre, Lunteren, Netherlands
- Year and Date
  2014-08-30 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異
- Author(s)
  趙一夢, 小川治夫, 米倉慎一郎, 三橋弘明, 豊島近, 石浦章一
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Large Production of SERCA toward determination of three-dimensional structures
- Author(s)
  Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
- Organizer
  14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease
- Place of Presentation
  De Werelt Conference Centre, Lunteren, Netherlands
- Year and Date
  2014-08-30 – 2014-09-05
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids
- Author(s)
  Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
- Organizer
  Biophysical Society 59th Annual meeting
- Place of Presentation
  Baltimore Convention Center, Baltimore, MD, USA
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析
- Author(s)
  小川治夫, 元山かん奈, Cornelius Flemming, Vilsen Bente, 豊島近
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids
- Author(s)
  Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
- Organizer
  Biophysical Society 59th Annual meeting
- Place of Presentation
  Baltimore Convention Center, Baltimore, MD, USA
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PUBLICLY-25136702
[Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構
- Author(s)
  森田真布, 小川治夫, 杖田淳子, 大野修, 矢守隆夫, 豊島近, 末永聖武
- Organizer
  日本化学会第95春季年会2015
- Place of Presentation
  日本大学理工学部船橋キャンパス/薬学部（千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25291012
[Presentation] X-ray crystallographic study of Na,K-ATPase in complex with cardiotonic steroids
- Author(s)
  Haruo Ogawa, Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi Toyoshima
- Organizer
  Biophysical Society 59th Annual meeting
- Place of Presentation
  Baltimore Convention Center, Baltimore, MD, USA
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Na+,K+-ATPaseと強心配糖体複合体のX線結晶構造解析
- Author(s)
  小川治夫, 元山かん奈, Cornelius Flemming, Vilsen Bente, 豊島近
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] Large Production of SERCA toward determination of three-dimensional structures
- Author(s)
  Haruo Ogawa, Yimeng Zhao, Ayami Hirata, Junko Tsueda, Shoichi Ishiura, Giuseppe Inesi, Chikashi Toyoshima
- Organizer
  14th International Conference Na,K-ATPase and related transport ATPases: Structure, mechanism, cell biology, health and disease
- Place of Presentation
  De Werelt Conference Centre, Lunteren, Netherlands
- Year and Date
  2014-08-30 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] X-線結晶構造解析が明かすビセリングビアサイド類のCa2+ポンプ阻害機構
- Author(s)
  森田真布, 小川治夫, 杖田淳子, 大野修, 矢守隆夫, 豊島近, 末永聖武
- Organizer
  日本化学会第95春季年会2015
- Place of Presentation
  日本大学理工学部船橋キャンパス/薬学部（千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25650020
[Presentation] 筋強直性ジストロフィーの病態に関わる筋小胞体Ca2+-ATPase 1スプライスバリアントの機能的差異
- Author(s)
  趙一夢, 小川治夫, 米倉慎一郎, 三橋弘明, 豊島近, 石浦章一
- Organizer
  第87回日本生化学会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-25136702

1. TOYOSHIMA Chikashi (70172210)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. Murayama Takashi (10230012)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
3. 呉林なごみ (50133335)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. KANAI Ryuta (50598472)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. 小林琢也 (60468585)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. TSUDA Takeo (10345233)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. MIMURA Hisatoshi (30463904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KABASHIMA Yoshiki (00580573)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. Kodama Masami (30512248)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
10. 冨田拓郎 (60705060)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 杉原匡美 (80648163)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. KONDOU Youhei (30436604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ISHIKITA Hiroshi (00508111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NAKASAKO Masayoshi (30227764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Yamazawa Toshio (00282616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 井上華 (20390700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 石田良典 (10937684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 加藤博章 (90204487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 清水啓史 (50324158)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 平井義和 (40452271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 萬谷博 (20321870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 加藤龍一 (50240833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. STOKES David L

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Inesi Giuseppe

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Vilsen Bente

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. Cornelius Flemming

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. Karlish Steven

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
28. KANEMARU Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
30. 末永聖武

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 飯野正光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 山口啓介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 井関雅子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 高橋徳志子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogawa Haruo 小川 治夫

OGAWA Haruo 小川 治夫

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創薬へ向けた心筋型リアノジン受容体の活性制御機構の構造的解明Principal Investigator

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膜1回貫通型受容体を対象にした「構造生物学での最後のフロンティア」解消への挑戦Principal Investigator

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Structural analysis of the gating mechanism of cardiac ryanodine receptorPrincipal Investigator

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Elucidation of tissue-specific calcium ion regulation mechanism by calcium pump by crystallographyPrincipal Investigator

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PLN/SERCA2aレギュラトームによる心収縮調節機構の解明Principal Investigator

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Ogawa Haruo 小川治夫

OGAWA Haruo 小川治夫