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Aoki Junken  青木 淳賢

… Alternative Names

AOKI Junken  青木 淳賢

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Researcher Number 20250219
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9435-1896
External Links
Affiliation (Current) 2025: 東京大学, 大学院薬学系研究科(薬学部), 教授
Affiliation (based on the past Project Information) *help 2020 – 2025: 東京大学, 大学院薬学系研究科(薬学部), 教授
2014 – 2019: 東北大学, 薬学研究科, 教授
2012 – 2015: 東北大学, 薬学研究科(研究院), 教授
2014: 東北大学, 大学院薬学研究科, 教授
2010 – 2011: 東北大学, 薬学研究科, 教授 … More
2007 – 2011: Tohoku University, 大学院・薬学研究科, 教授
2006: 東京大学, 大学院薬学研究科, 助教授
2005 – 2006: 東京大学, 大学院薬学系研究科, 助教授
2000 – 2005: THE TOKYO UNIVERSITY PHARMACEUTICAL SCIENCES, ASSISTANT PROFESSOR, 大学院・薬学系研究科, 助教授
2004: 東京大学, 薬学系研究科, 助教授
1997 – 1999: 東京大学, 大学院・薬学系研究科, 助手
1994 – 1996: Univ.of Tokyo, Faculty of Pharmaceutical Sciences, Assistant Professor, 薬学部, 助手
1994: (財)東京都臨床医学総合研究所, 微生物研究部門, 研究員
1994: (財)都臨床医学総合研究所微生物部, 研究員
1993 – 1994: (財)都臨床医学総合研究所, 微生物部, 研究員
1993: 微生物, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological Sciences / Biological pharmacy / Medium-sized Section 47:Pharmaceutical sciences and related fields / Biological Sciences / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Functional biochemistry / Functional biochemistry
Except Principal Investigator
Biological pharmacy … More / Biological Sciences / Biological Sciences / Basic Section 52030:Psychiatry-related / Applied biochemistry / Pathological medical chemistry / 応用薬理学・医療系薬学 / Virology / Respiratory surgery / Cell biology Less
Keywords
Principal Investigator
リゾホスファチジン酸 / GPCR / リゾリン脂質 / リゾホスファチジルセリン / 受容体 / ノックアウトマウス / 産生酵素 / オートタキシン / がん / マスト細胞 … More / ホスホリパーゼ / 生理活性脂質 / LPA / 免疫 / B細胞 / lysophosphatidic acid / 脂肪酸 / リン脂質 / ゼブラフィッシュ / 多様性 / ホスホリパーゼA1 / 浸潤・転移 / autotaxin / 感染症 / がん免疫 / LPC / lysoPLD / LPA3 / lysophospholipase D / ホスホリパーゼA2 / リゾホスホリパーゼD / LC-MS/MS / 作動薬 / 酸化リン脂質 / メディエーター / Gタンパク質共役型受容体 / 脱顆粒 / 血管新生 / 血管形成 / LPA受容体 / 着床 / ホスホリパーゼA_1 / ヒスタミン / ホスファチジルセリン / MS Imaging / 脂肪酸分子種 / ホスホリパーゼA / リン脂質リモデリング / パルミチン酸 / AdipoR2 / マクロファージ / LysoPS / 感染症免疫 / オレイン酸 / 非対称性 / LPGAT1 / リゾリン脂質アシルトランスフェラーゼ / リン脂質分子種 / ミトコンドリア / ステアリン酸 / 生物学的意義 / 活性化リンパ球 / G12/13 / 免疫増強 / 免疫機能 / 炎症反応 / PS-PLA1 / 接触性皮膚炎 / 細胞死 / 迷走神経 / セリン / 抗体 / リンパ球 / 抗原免疫 / lysophosphatidylcholine / リゾホスファチジルコリン / リゾボスファチジルコリン / リゾボスホリパーゼD / リゾボスファチジン酸 / prostaglandin / knockout mice / implantation / リゾホスファチジン酸受容体 / プロスタグランジン / methastasis / cancer / phospholipose / リゾホスホリパーゼ / ホスホリパーゼD / リゾホスフォリパーゼD / ホスリパーゼ / 質量分析計 / 2-アシル型リゾリン脂質 / 2-アシルリゾリン脂質 / 質量分析 / 自己免疫疾患 / 脂質メディエーター / 免疫抑制 / TGF / 脂肪酸組成 / 生体膜 / アシルトランスフェラーゼ / remodeling / massspectrometry / fatty acid / PLA1 / 酸化LDL / 質量分析機器 / マススペクトロメトリー / モデル生物 / TALEN / マウス / 脱顆粒反応 / リゾボスファチジルセリン / リゾホスファチジルスレオニン / モノクローナル抗体 / RNA干渉法 / 線虫 / 非対称分裂 / 細胞内輸送 / ATX / リゾホスフチジン酸受容体 / PS-PLA_1 / セリンリン脂質特異的ホスホリパーゼA / GPI / NCAM / 細胞移動 / 接着因子 / PAFアセチルヒドラーゼ / 血小板活性化因子 / 接着タンパク / MPH / PVRマウスホモログ / PVR / ポリオウイルスレセプター … More
Except Principal Investigator
PAF / 血小板活性化因子 / HDL / ホスホリパーゼA1 / リゾホスファチジルセリン / 酸化リン脂質 / ロイコトリエン / ホスホリパーゼA_1 / リゾホスファチジン酸 / ノックアウトマウス / コレステロール / PVR / 創薬 / KNOCKOUT MICE / PHOSPHOLIPASE A1 / SR-BI / 基質特異性 / 輸送蛋白質 / ビタミンE / ホスホリパーゼA2 / C.elegans / PAF-AH / PS-PLA1 / ホスファチジルセリン / LDL / CETP / Poliovirus / トランスジェニックマウス / ポリオウイルス / 脳 / 炎症 / ホスホリパーゼA_2 / プロスタグランジン / ホスホリパーゼ / 生理活性脂質 / ホスホリパーゼD / ホスファチジン酸 / EDG7 / 脳神経疾患 / 遺伝病 / 分解酵素 / 細胞内輸送 / マクロファージ / 神経細胞移動 / PAFアセチルハイドロラーゼ / 患者層別化 / 抗うつ薬 / リゾリン脂質 / 層別化 / リゾフォスファチジン酸受容体1 / リゾリン脂質代謝 / うつ病 / がん / 疾患モデル / リン酸化 / シグナル伝達 / 酵素 / 脂質 / ホスファターゼ / キナーゼ / イノシトール / 脂肪酸 / リン脂質 / 細胞膜 / 脂質代謝酵素 / 病態モデル / 質量分析 / イノシトールリン脂質 / 遺伝子改変マウス / リン脂質代謝酵素 / 膜リン脂質 / 神経科学 / 生殖工学 / 骨粗鬆症 / 誘発分娩 / 縫線核 / 骨代謝 / CRISPR/Cas9 / 社会記憶 / 扁桃体内側核 / 内側中核 / 神経内分泌学 / GPCR / 向社会性 / 行動神経科学 / 神経内分泌 / 分娩 / 外側中隔 / STP(Serial two-photon tomograph) / 自閉症スペクトラム障害 / アゴニスト / 平原ハタネズミ / 向社会行動 / DREADDs / Prairie Vole / 下垂体後葉ホルモン / 神経回路解析 / 共感性行動 / 向社会性行動 / オキシトシン受容体 / オキシトシン / MAST CLL / ENDOTOXIN SHOCK / PHOSPHATIDYLSERINE / LYSOPHOSPHATIDYL SERINE / セリンリン脂質特異的ホスホリパーゼ / アレルギー / PS-PLA_1 / マスト細胞 / リゾフォスファチジルセリン / エンドトキシンショック / PHOSPHOLIPASE A2 / PHOSPHOLIPASE A / platelet-activating factor / ノックアウト / 線虫 / ホスホリパーゼA / SERCRETION / LIVER / TRANSPORT PROTEIN / VITAMIN E / PDZ DOMAIN / CHOLESTEROL / 脂質ソーティング / 小胞輸送 / ABCトランスポーター / 輸送タンパク質 / 分泌 / 肝臓 / PDZドメイン / BERGMANN GLIA / KNOCKOUT MOUSE / OXIDATIVE STRESS / VITAMINE / バーグマングリア細胞 / プルキンエ細胞 / 小脳 / バーグマングリア / 酸素ストレス / phosphatidylserine / PAF acetylhydrolase / 酵素ストレス / PS / セリン特異的ホスホリパーゼ / PAFアセチルヒドロラーゼ / Transgenic mouse / Blood-brain barrier : / Organ tropism / Brain / Vaccine / Pharmacokinetics / Virus receptor / 血液脳関門 / 臓器選択性 / ワクチン / ウイルス製剤 / ウイルス受容体 / SRBI / Macropage / Choresterol / スフィンゴミエリン / ホスファチジルコリン / アポE / 動脈硬化 / トランスポート / ライソソーム / リポ蛋白質 / 変性LDL / スカベンジャー受容体 / SRB1 / Transgenic mice / ワクチン検定 / レセプター / lissencephaly / platelet activating factor / Calcium ion / Degranulation / Mast cell / Inflammation / Prostaglandins / Phospholipase A_2 / アラキドン酸 / 繊維芽細胞 / 肝細胞 / TNF / リポポリサッカライド / 酸化脂肪酸 / WD-40リピート / ヒト無脳回症 / PAF受容体 / セリンエステラーゼ / 無脳回症 / カルシウムイオン / 脱顆粒反応 / 肥満細胞 / オートタキシン / 免疫学 / 移植 / 閉塞性細気管支炎 / モデルマウス / LPA / 肺移植 / 質量分析計 / 質量分析機 / 遺伝子欠損マウス / 脂質メディエーター / 非ステロイド性消炎鎮痛薬 / エイコサノイド / オーファン受容体 / 酸化遊離脂肪酸 / リン脂質生合成 / 5-リポキシゲナーゼ / 2-アラキドノイルグリセロール / Gタンパク質共役型受容体 / 滑脳症 / LIS1 / 精子形成 / 神経回路形成 / 神経突起伸長 / γサブユニット / ニーマン・ピック病 / コレステロール輸送 / ライソゾーム膜 / モノクローン抗体 / 細胞接着 / 免疫グロブリンスーパーファミリー / ポリオウイルスレセプター Less
  • Research Projects

    (53 results)
  • Research Products

    (419 results)
  • Co-Researchers

    (68 People)
  •  リン脂質リモデリングの分子機構と生物学的意義の解明Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      The University of Tokyo
  •  Stratification of depression based on lysophospholipid metabolic disorders and innovative development of novel antidepressants

    • Principal Investigator
      竹林 実
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52030:Psychiatry-related
    • Research Institution
      Kumamoto University
  •  Characterization and functional elucidation of a novel group of phospholipase A enzymes that define the fatty acid species of phospholipidsPrincipal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      The University of Tokyo
  •  Elucidation of immunoregulatory roles of lysophospholipid mediators and their pharmacological significancePrincipal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      The University of Tokyo
  •  Elucidating the biological significance of phospholipid speciesPrincipal Investigator

    • Principal Investigator
      Aoki Junken
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      The University of Tokyo
  •  Identification of synthetic pathway for lysophosphatidylserine in activated lymphocytes.Principal Investigator

    • Principal Investigator
      Aoki Junken
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      The University of Tokyo
      Tohoku University
  •  Role of lysophospholipid produced upon cell death.Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Identification and functional analysis of a mast cell lysophosphatidylserine receptor.Principal Investigator

    • Principal Investigator
      Aoki Junken
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  A novel immunomodulatory role of a lysophospholipid mediator, lysophosphatidylserine,, in lynphocytes.Principal Investigator

    • Principal Investigator
      AOKI JUNKEN
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Expansion of the study of Oxytocin Receptor, which has diverse physiological functions, and establishment of a new agonist analysing system.

    • Principal Investigator
      Nishimori Katsuhiko
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied biochemistry
    • Research Institution
      Fukushima Medical University
      Tohoku University
  •  Analyses of membrane phospholipid quality

    • Principal Investigator
      Sasaki Takehiko
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
      Akita University
  •  Intracellular roles of 2-acyl-lysophospholipidsPrincipal Investigator

    • Principal Investigator
      Aoki Junken
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Immunosuppressive role of lysophosphatidylserine and its evaluation as drug targetsPrincipal Investigator

    • Principal Investigator
      Aoki Junken
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  The study for suppression of obliterative bronchiolitis by inhibiting autotaxin activity

    • Principal Investigator
      YUKIKO Tando
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Respiratory surgery
    • Research Institution
      Tohoku University
  •  Biological roles of fatty acid composition of phospholipids.Principal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Lipid machinery

    • Principal Investigator
      YOKOMIZO Takehiko
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Juntendo University
      Kyushu University
  •  Comprehensive analysis of lysophospholipids using model animalsPrincipal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Identification of a novel GPCR for oxidized LDL and its role in development of arteriosclerosis.Principal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Comprehensive analyses of bioactive lysophospholipidsPrincipal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  The functions of autotaxin in the regulation of blood vessel formationPrincipal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Patho-physiological role of bioactive lysophospholipidsPrincipal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  新規スレオニン含有リン脂質のマスト細胞における機能と産生機構の解明Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  生理活性脂質リゾホスファチジン酸による血管新生・細胞浸潤・転移制御とその意義Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      The University of Tokyo
  •  新規細胞内型ホスホリパーゼA1による逆行性輸送制御機構の解明Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      The University of Tokyo
  •  マスト細胞の多様性とその意義Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  生理活性脂質リゾホスファチジン酸によるがん細胞の増殖・浸潤制御とその意義Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Patho-Physiological role of lysophosphatidic acid.Principal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Autotaxinの癌細胞浸潤・転移促進機構の解明とその応用Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  がん細胞の転移・浸潤能とリゾホスファチジン酸の関連Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Physiological role of lysophosphatidic acid.Principal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokyo
  •  新規生理活性脂質の生体機能

    • Principal Investigator
      和泉 孝志
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Gunma University
  •  Mechanism of Iyshosphatidic acid production.Principal Investigator

    • Principal Investigator
      AOKI Junken
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  神経細胞移動を制御するLIS1カスケードおよびその制御機構の解明

    • Principal Investigator
      新井 洋由 (新井 洋田)
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  リゾホスファチジン酸の生理機能の解明と病態との関連-創薬に向けた基盤研究-

    • Principal Investigator
      新井 洋由
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  新規リゾリン脂質性メディエーター"リゾPS"の生体内機能と作用機構の解明Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Novel functions of phospholipases

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (B)
    • Review Section
      Biological Sciences
    • Research Institution
      Teikyo University
      The University of Tokyo
  •  Patho-Physiological function of Phosphatidylserine-specific Phospholipase A1-Specific role of PS-PLA 1 in mast cell activation-

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biological pharmacy
    • Research Institution
      Teikyo University
      The University of Tokyo
  •  血小板から分泌されるホスファチジルセリン特異的ホスホリパーゼの構造と機能Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Biological and pharmaceutical studies on the mechanism of intracellular sorting of cholesterol and vitamin E

    • Principal Investigator
      KRAI Hiroyuki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      GRADUATE SCHOOL OF PHARMACEUTICAL SCIENCES, THE UNIVERSITY OF TOKYO
  •  コレステロールのプロトン共役性膜透過機構の解析

    • Principal Investigator
      新井 洋由
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  PAFの脳内機能-PAFアセチルハイドロラーゼによる制御機構の解析-

    • Principal Investigator
      井上 圭三
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  GPI型NCAMの細胞外放出に関与する新規ホスホリパーゼPrincipal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  NEW FUNCTION OF PHOSPHOLIPASE A

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Production and application of novel model animals with an oxidative stress

    • Principal Investigator
      ARAI Hiroyuki
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      GRADUATE SCHOOL OF PHARMACEUTICAL SCIENCES,THE UNIVERSITY OF TOKYO
  •  コレステロールのプロトン共役性膜透過機構の解析

    • Principal Investigator
      ARAI Hiroyuki
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  PAFの脳内機能-PAFアセチルヒドロラーゼによる制御機構の解析-

    • Principal Investigator
      井上 圭三
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  血小板活性化因子(PAF)と細胞接着因子Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Development of Pharmacokinetic and Safety Assessment of in vivo Virus Infection and Vaccine Therapy

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tohoku University
      The University of Tokyo
  •  ポリオウイルスレセプターは細胞間認識に関与するか?Principal Investigator

    • Principal Investigator
      青木 淳賢
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Functional biochemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Basic study for analysis and application of bio-factor which regulate transfer of cholresterol in vivo.

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      University of Tokyo
  •  新しい免疫グロブリンスーパーファミリーに属する膜タンパク質の機能解析

    • Principal Investigator
      小池 智
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research
  •  Biological functions of mammalian non-pacreatic type Phospholipase A_2

    • Principal Investigator
      INOUE Keizo
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      University of Tokyo
  •  Development of new quality control method for oral live vaccine using transgenic mice susceptible to poliovirus.

    • Principal Investigator
      KURATA Takeshi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (A)
    • Research Field
      Virology
    • Research Institution
      National Institute of Health

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent Other

  • [Book] オレオサイエンス2013

    • Author(s)
      中永景太、井上飛鳥、青木淳賢
    • Total Pages
      613
    • Publisher
      日本油化学会
    • Data Source
      KAKENHI-PROJECT-24659025
  • [Book] 実験医学, 「情報伝達をつかさどる生理活性物質脂質メディエーターの機能」2009

    • Author(s)
      井上飛鳥/青木淳賢
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Book] 「ホスホリパーゼA1の構造と機能」オレオサイエンス

    • Author(s)
      中永景太、井上飛鳥、青木淳賢
    • Publisher
      (Vol. 13)
    • Data Source
      KAKENHI-PROJECT-24659025
  • [Journal Article] G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression.2024

    • Author(s)
      Kajitani, N., Okada-Tsuchioka, M., Inoue, A., Miyano, K., Masuda, T., Boku, S., Iwamoto, K., Ohtsuki, S., Uezono, Y., Aoki, J., Takebayashi, M.
    • Journal Title

      Neuropsychopharmacology

      Volume: 49 Issue: 3 Pages: 561-572

    • DOI

      10.1038/s41386-023-01727-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07750, KAKENHI-PROJECT-21K07501, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-23K27530
  • [Journal Article] Direct activation of microglia by β-glucosylceramide causes phagoptosis of neurons that exacerbates Gaucher disease.2023

    • Author(s)
      Shimizu T, Schutt C R, Izumi Y, Tomiyasu N, Omahdi Z, Kano K, Takamatsu H, Aoki J, Bamba T, Kumanogoh A, Takao M, Yamasaki S*.
    • Journal Title

      Immunity

      Volume: 56 Issue: 2 Pages: 1-13

    • DOI

      10.1016/j.immuni.2023.01.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K18924, KAKENHI-PLANNED-22H05183, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-22KJ2427, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-22H00438
  • [Journal Article] Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 342023

    • Author(s)
      Sugihara Ryuta、Taneike Manabu、Murakawa Tomokazu、Tamai Takahito、Ueda Hiromichi、Kitazume-Taneike Rika、Oka Takafumi、Akazawa Yasuhiro、Nishida Hiroki、Mine Kentaro、Hioki Ayana、Omi Jumpei、Omiya Shigemiki、Aoki Junken、Ikeda Kazutaka、Nishida Kazuhiko、Arita Makoto、Yamaguchi Osamu、Sakata Yasushi、Otsu Kinya
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4494-4494

    • DOI

      10.1038/s41467-023-40201-4

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K21350, KAKENHI-PROJECT-20K08491, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
  • [Journal Article] Emerging roles of lysophosphatidylserine as an immune modulator2023

    • Author(s)
      Yaginuma Shun、Omi Jumpei、Uwamizu Akiharu、Aoki Junken
    • Journal Title

      Immunological Reviews

      Volume: - Issue: 1 Pages: 20-29

    • DOI

      10.1111/imr.13204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15272, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
  • [Journal Article] LPGAT1/LPLAT7 regulates acyl chain profiles at the sn-1 position of phospholipids in murine skeletal muscles2023

    • Author(s)
      Sato Tomoki、Umebayashi Shuhei、Senoo Nanami、Akahori Takumi、Ichida Hiyori、Miyoshi Noriyuki、Yoshida Takuya、Sugiura Yuki、Goto-Inoue Naoko、Kawana Hiroki、Shindou Hideo、Baba Takashi、Maemoto Yuki、Kamei Yasutomi、Shimizu Takao、Aoki Junken、Miura Shinji
    • Journal Title

      Journal of Biological Chemistry

      Volume: 299 Issue: 7 Pages: 104848-104848

    • DOI

      10.1016/j.jbc.2023.104848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18179, KAKENHI-PROJECT-23K18436, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-22K17831, KAKENHI-PROJECT-21H03362, KAKENHI-PROJECT-23K24796
  • [Journal Article] Phosphatidylserine synthesis controls oncogenic B cell receptor signaling in B cell lymphoma2023

    • Author(s)
      Omi Jumpei、Kato Taiga、Yoshihama Yohei、Sawada Koki、Kono Nozomu、Aoki Junken
    • Journal Title

      Journal of Cell Biology

      Volume: 223 Issue: 2

    • DOI

      10.1083/jcb.202212074

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18179, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15272, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
  • [Journal Article] Synthesis and Biological Evaluation of Lysophosphatidic Acid Analogues Using Conformational Restriction and Bioisosteric Replacement Strategies2023

    • Author(s)
      Abdelwahid Mazin A. S.、Ohsawa Kosuke、Uwamizu Akiharu、Kano Kuniyuki、Aoki Junken、Doi Takayuki
    • Journal Title

      ACS Omega

      Volume: 8 Issue: 51 Pages: 49278-49288

    • DOI

      10.1021/acsomega.3c07668

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-22H05336, KAKENHI-PROJECT-22H00438
  • [Journal Article] Lysophospholipids and their producing enzymes: Their pathological roles and potential as pathological biomarkers2023

    • Author(s)
      Yaginuma Shun、Omi Jumpei、Kano Kuniyuki、Aoki Junken
    • Journal Title

      Pharmacology & Therapeutics

      Volume: 246 Pages: 108415-108415

    • DOI

      10.1016/j.pharmthera.2023.108415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15272, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-22H00438
  • [Journal Article] Current Knowledge on Mammalian Phospholipase A1, Brief History, Structures, Biochemical and Pathophysiological Roles2022

    • Author(s)
      Yaginuma Shun、Kawana Hiroki、Aoki Junken
    • Journal Title

      Molecules

      Volume: 27 Issue: 8 Pages: 2487-2487

    • DOI

      10.3390/molecules27082487

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22H00438
  • [Journal Article] The Many Roles of Lysophospholipid Mediators and Japanese Contributions to This Field2022

    • Author(s)
      Takagi Yugo、Nishikado Shun、Omi Jumpei、Aoki Junken
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 45 Issue: 8 Pages: 1008-1021

    • DOI

      10.1248/bpb.b22-00304

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2022-08-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15272, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-19H03366, KAKENHI-PROJECT-22H00438
  • [Journal Article] Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation2022

    • Author(s)
      N Kondo, Y Sakurai, T Takata, K Kano, K Kume, M Maeda, N Takai, S Suzuki et al.,
    • Journal Title

      scientific reports

      Volume: 12 Issue: 1 Pages: 8718-8718

    • DOI

      10.1038/s41598-022-12293-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03620, KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-22H00438
  • [Journal Article] TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis2022

    • Author(s)
      Petkevicius Kasparas、Palmgren Henrik、 他19人、Kono Nozomu、Aoki Junken、Hess Sonja、Sienski Grzegorz、Pilon Marc、Bohlooly-Y Mohammad、Maresca Marcello、Peng Xiao-Rong
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 6020-6020

    • DOI

      10.1038/s41467-022-33735-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
  • [Journal Article] Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity2022

    • Author(s)
      Valentine William J.、Yanagida Keisuke、Kawana Hiroki、Kono Nozomu、Noda Nobuo N.、Aoki Junken、Shindou Hideo
    • Journal Title

      Journal of Biological Chemistry

      Volume: 298 Issue: 1 Pages: 101470-101470

    • DOI

      10.1016/j.jbc.2021.101470

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05707, KAKENHI-PROJECT-20K08900, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-20K21379
  • [Journal Article] Changes in Lysophospholipid Components in Ulcerative Colitis and Colitis-associated Cancer2022

    • Author(s)
      SONODA HIROFUMI、KITAMURA CHIEKO、KANO KUNIYUKI、ANZAI HIROYUKI、NAGAI YUZO、ABE SHINYA、YOKOYAMA YUICHIRO、ISHII HIROAKI、KISHIKAWA JUNKO、MURONO KOJI、EMOTO SHIGENOBU、SASAKI KAZUHITO、KAWAI KAZUSHIGE、NOZAWA HIROAKI、AOKI JUNKEN、ISHIHARA SOICHIRO
    • Journal Title

      Anticancer Research

      Volume: 42 Issue: 5 Pages: 2461-2468

    • DOI

      10.21873/anticanres.15724

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-19H03366
  • [Journal Article] Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish2022

    • Author(s)
      Shibata T, Kawana H, Nishino Y, Ito Y, Sato H, Onishi H, Kano K, Inoue A, Taketomi Y, Murakami M, Kofuji S, Nishina H, Miyazawa A, Kono N, Aoki J.
    • Journal Title

      Scientific reports

      Volume: 12 Issue: 1 Pages: 7312-7312

    • DOI

      10.1038/s41598-022-11002-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K15984, KAKENHI-PROJECT-21K06544, KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-20H05691, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
  • [Journal Article] Dietary <i>Lactobacillus</i>-Derived Exopolysaccharide Enhances Immune-Checkpoint Blockade Therapy2022

    • Author(s)
      Kawanabe-Matsuda Hirotaka、Takeda Kazuyoshi、Nakamura Marie、Makino Seiya、Karasaki Takahiro、Kakimi Kazuhiro、Nishimukai Megumi、Ohno Tatsukuni、Omi Jumpei、Kano Kuniyuki、Uwamizu Akiharu、Yagita Hideo、Boneca Ivo Gomperts、Eberl G?rard、Aoki Junken、Smyth Mark J.、Okumura Ko
    • Journal Title

      Cancer Discovery

      Volume: - Issue: 5 Pages: 1336-1355

    • DOI

      10.1158/2159-8290.cd-21-0929

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11598, KAKENHI-PROJECT-22K15272, KAKENHI-PROJECT-22KJ0530, KAKENHI-PROJECT-23K21391, KAKENHI-PROJECT-22H00438
  • [Journal Article] Secreted phospholipase A2 modifies extracellular vesicles and accelerates B cell lymphoma2022

    • Author(s)
      Kudo Kai、Miki Yoshimi、Carreras Joaquim、Nakayama Shunya、Nakamoto Yasushi、Ito Masatoshi、Nagashima Etsuko、Yamamoto Kei、Higuchi Hiroshi、Morita Shin-ya、Inoue Asuka、Aoki Junken、Ando Kiyoshi、Nakamura Naoya、Murakami Makoto、Kotani Ai
    • Journal Title

      Cell Metabolism

      Volume: 34 Issue: 4 Pages: 615-633

    • DOI

      10.1016/j.cmet.2022.02.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-20H04939, KAKENHI-PROJECT-19H03372, KAKENHI-PROJECT-19K07042, KAKENHI-PROJECT-21K15420, KAKENHI-PROJECT-20H05691, KAKENHI-PROJECT-22H00438
  • [Journal Article] Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase2022

    • Author(s)
      Kawana Hiroki、Ozawa Masaya、Shibata Takeaki、Onishi Hirofumi、Sato Yukitaka、Kano Kuniyuki、Shindou Hideo、Shimizu Takao、Kono Nozomu、Aoki Junken
    • Journal Title

      Journal of Lipid Research

      Volume: 63 Issue: 10 Pages: 100271-100271

    • DOI

      10.1016/j.jlr.2022.100271

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19327, KAKENHI-PROJECT-22K15273, KAKENHI-PROJECT-20K21379, KAKENHI-PUBLICLY-21H00228, KAKENHI-PROJECT-20H03380
  • [Journal Article] Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag2021

    • Author(s)
      Iwama Taiga、Kano Kuniyuki、Saigusa Daisuke、Ekroos Kim、van Echten-Deckert Gerhild、Vogt Johannes、Aoki Junken
    • Journal Title

      Analytical Chemistry

      Volume: 93 Issue: 8 Pages: 3867-3875

    • DOI

      10.1021/acs.analchem.0c04479

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07047, KAKENHI-PROJECT-20K21379, KAKENHI-PROJECT-20H03374
  • [Journal Article] Non-naturally Occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity toward G Protein-Coupled Receptors2020

    • Author(s)
      Nakamura Sho、Sayama Misa、Uwamizu Akiharu、Jung Sejin、Ikubo Masaya、Otani Yuko、Kano Kuniyuki、Omi Jumpei、Inoue Asuka、Aoki Junken、Ohwada Tomohiko
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 63 Issue: 17 Pages: 9990-10029

    • DOI

      10.1021/acs.jmedchem.0c01126

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06962, KAKENHI-PROJECT-19H03366
  • [Journal Article] Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism.2020

    • Author(s)
      Nakawatari K, Kurano M, Araki O, Nishikawa M, Shimamoto S, Igarashi K, Aoki J, Murakami M, Yatomi Y.
    • Journal Title

      Clin Chim Acta.

      Volume: 503 Pages: 99-106

    • DOI

      10.1016/j.cca.2020.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-17H04109, KAKENHI-PROJECT-20H03573, KAKENHI-PROJECT-19H03366
  • [Journal Article] Membrane Phospholipid Analogues as Molecular Rulers to Probe the Position of the Hydrophobic Contact Point of Lysophospholipid Ligands on the Surface of G-Protein-Coupled Receptor during Membrane Approach2020

    • Author(s)
      Sayama Misa、Uwamizu Akiharu、Otani Yuko、Inoue Asuka、Aoki Junken、Sekijima Masakazu、Ohwada Tomohiko
    • Journal Title

      Biochemistry

      Volume: 59 Issue: 11 Pages: 1173-1201

    • DOI

      10.1021/acs.biochem.0c00061

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-19H03366
  • [Journal Article] Serum phosphatidylserine-specific phospholipase A1 as a novel biomarker for monitoring systemic lupus erythematosus disease activity.2019

    • Author(s)
      Sawada T, Kurano M, Shirai H, Iwasaki Y, Tahara K, Hayashi H, Igarashi K, Fujio K, Aoki J, Yatomi Y.
    • Journal Title

      Int J Rheum Dis

      Volume: 22 Issue: 11 Pages: 2059-2066

    • DOI

      10.1111/1756-185x.13689

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-19H03366
  • [Journal Article] GPR34 in spinal microglia exacerbates neuropathic pain in mice2019

    • Author(s)
      Sayo Akira、Konishi Hiroyuki、Kobayashi Masaaki、Kano Kuniyuki、Kobayashi Hiroki、Hibi Hideharu、Aoki Junken、Kiyama Hiroshi
    • Journal Title

      Journal of Neuroinflammation

      Volume: 16 Issue: 1 Pages: 23-33

    • DOI

      10.1186/s12974-019-1458-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05494, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19K24067, KAKENHI-PROJECT-19H03395
  • [Journal Article] Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay2018

    • Author(s)
      Ohkawa Ryunosuke、Kurano Makoto、Sakai Noboru、Kishimoto Tatsuya、Nojiri Takahiro、Igarashi Koji、Hosogaya Shigemi、Ozaki Yukio、Dohi Tomotaka、Miyauchi Katsumi、Daida Hiroyuki、Aoki Junken、Okubo Shigeo、Ikeda Hitoshi、Tozuka Minoru、Yatomi Yutaka
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1-12

    • DOI

      10.1038/s41598-018-23009-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15771, KAKENHI-PUBLICLY-17H05494, KAKENHI-PROJECT-16H06236, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906
  • [Journal Article] Lysophospholipids in laboratory medicine2018

    • Author(s)
      YATOMI Yutaka、KURANO Makoto、IKEDA Hitoshi、IGARASHI Koji、KANO Kuniyuki、AOKI Junken
    • Journal Title

      Proceedings of the Japan Academy, Series B

      Volume: 94 Issue: 10 Pages: 373-389

    • DOI

      10.2183/pjab.94.025

    • NAID

      130007529097

    • ISSN
      0386-2208, 1349-2896
    • Year and Date
      2018-12-11
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16H06236
  • [Journal Article] Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos2018

    • Author(s)
      Noguchi Takuya、Suzuki Midori、Mutoh Natsumi、Hirata Yusuke、Tsuchida Mei、Miyagawa Sayoko、Hwang Gi-Wook、Aoki Junken、Matsuzawa Atsushi
    • Journal Title

      Cell Death & Disease

      Volume: 9 Issue: 12 Pages: 1193-1193

    • DOI

      10.1038/s41419-018-1245-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06622, KAKENHI-PROJECT-18K14894, KAKENHI-PUBLICLY-17H05494, KAKENHI-PUBLICLY-17H05518, KAKENHI-PROJECT-18H02567
  • [Journal Article] Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma2018

    • Author(s)
      Kurano Makoto、Miyagaki Tomomitsu、Miyagawa Takuya、Igarashi Koji、Shimamoto Satoshi、Ikeda Hitoshi、Aoki Junken、Sato Shinichi、Yatomi Yutaka
    • Journal Title

      The Journal of Dermatology

      Volume: - Issue: 5 Pages: 571-579

    • DOI

      10.1111/1346-8138.14278

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H06236, KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16H05085
  • [Journal Article] Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study2018

    • Author(s)
      Kuwajima Ken、Sumitani Masahiko、Kurano Makoto、Kano Kuniyuki、Nishikawa Masako、Uranbileg Baasanjav、Tsuchida Rikuhei、Ogata Toru、Aoki Junken、Yatomi Yutaka、Yamada Yoshitsugu
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 11 Pages: 0207310-0207310

    • DOI

      10.1371/journal.pone.0207310

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PUBLICLY-17H05494
  • [Journal Article] Analysis of glycero-lysophospholipids in gastric cancerous ascites.2017

    • Author(s)
      Emoto, S., Kurano, M., Kano, K., Matsusaki, K., Yamashita, H., Nishikawa, M., Igarashi, K., Ikeda, H., Aoki, J., Kitayama, J., and Yatomi, Y.
    • Journal Title

      J. Lipid Res

      Volume: 58 Issue: 4 Pages: 763-771

    • DOI

      10.1194/jlr.p072090

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-16H06236, KAKENHI-PROJECT-16H05085, KAKENHI-PLANNED-15H05906
  • [Journal Article] Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS1 by Docking-Aided Structure?Activity Analysis2017

    • Author(s)
      Sayama Misa、Inoue Asuka、Nakamura Sho、Jung Sejin、Ikubo Masaya、Otani Yuko、Uwamizu Akiharu、Kishi Takayuki、Makide Kumiko、Aoki Junken、Hirokawa Takatsugu、Ohwada Tomohiko
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 60 Issue: 14 Pages: 6384-6399

    • DOI

      10.1021/acs.jmedchem.7b00693

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08157, KAKENHI-PUBLICLY-16H00822, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16J08059, KAKENHI-PROJECT-17J02597, KAKENHI-PROJECT-16K15113
  • [Journal Article] Lysophosphatidylserine suppresses IL-2 production in CD4 T cells through LPS3/GPR174.2017

    • Author(s)
      Shinjo Y, Makide K, Satoh K, Fukami F, Inoue A, Kano K, Otani Y, Ohwada T, Aoki J
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 494 Issue: 1-2 Pages: 332-338

    • DOI

      10.1016/j.bbrc.2017.10.028

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-15J03325
  • [Journal Article] Phospholipid localization implies microglial morphology and function via Cdc42 in vitro2017

    • Author(s)
      Kyohei Tokizane, Hiroyuki Konishi, Kumiko Makide, Hiroki Kawana, Shinichi Nakamuta, Kozo Kaibuchi, Tomohiko Ohwada, Junken Aoki, Hiroshi Kiyama
    • Journal Title

      Glia

      Volume: 65 Issue: 5 Pages: 740-755

    • DOI

      10.1002/glia.23123

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15J02662, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-16K15113, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16H05117
  • [Journal Article] Conformational Constraint of the Glycerol Moiety of Lysophosphatidylserine, an Emerging Lysophospholipid Mediator, Affords Compounds with Receptor Subtype Selectivity2016

    • Author(s)
      Sejin Jung, Asuka Inoue, Sho Nakamura, Takayuki Kishi, Akiharu Uwamizu, Misa Sayama, Masaya Ikubo, Yuko Otani, Kuniyuki Kano, Kumiko Makide, Junken Aoki, Tomohiko Ohwada
    • Journal Title

      The Journal of Medicinal Chemistry

      Volume: 59 Issue: 8 Pages: 3750-3776

    • DOI

      10.1021/acs.jmedchem.5b01925

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H00822, KAKENHI-PROJECT-16J02800, KAKENHI-PROJECT-16J08059, KAKENHI-PROJECT-15K07919, KAKENHI-PROJECT-16K08157, KAKENHI-PROJECT-16K15113, KAKENHI-PROJECT-16H05085
  • [Journal Article] Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction2016

    • Author(s)
      Nagura, Y., Tsuno, NH., Kano, K., Inoue, A., Aoki, J., Hirowatari, Y., Kaneko, M., Kurano, M., Matsuhashi, M., Ohkawa, R., Tozuka, M., Yatomi, Y., and Okazaki, H.
    • Journal Title

      Transfus. Med.

      Volume: 26 Issue: 5 Pages: 365-372

    • DOI

      10.1111/tme.12326

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05906, KAKENHI-PROJECT-16H05085
  • [Journal Article] Structure-Activity Relationships of Lysophosphatidylserine Analogs as Agonists of G-Protein-Coupled Receptors GPR34, P2Y10, and GPR1742015

    • Author(s)
      Masaya Ikubo, Asuka Inoue, Sho Nakamura, Sejin Jung, Misa Sayama, Yuko Otani, Akiharu Uwamizu, Keisuke Suzuki, Takayuki Kishi, Akira Shuto, Jun Ishiguro, Michiyo Okudaira, Kuniyuki Kano, Kumiko Makide, Junken Aoki, and Tomohiko Ohwada
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: 58 Issue: 10 Pages: 4204-4219

    • DOI

      10.1021/jm5020082

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460009, KAKENHI-PROJECT-25293010, KAKENHI-PUBLICLY-26104508
  • [Journal Article] Lysophosphatidylserine analogues differentially activate three LysoPS receptors2015

    • Author(s)
      Akiharu Uwamizu, Asuka Inoue, Kensuke Suzuki, Michiyo Okudaira, Akira Shuto, Yuji Shinjo, Jun Ishiguro, Kumiko Makide, Masaya Ikubo, Sho Nakamura, Sejin Jung, Misa Sayama, Yuko Otani, Tomohiko Ohwada and Junken Aoki
    • Journal Title

      Journal of biochemistry

      Volume: 157 Issue: 3 Pages: 151-160

    • DOI

      10.1093/jb/mvu060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J07566, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-25293010, KAKENHI-PROJECT-25460009, KAKENHI-PUBLICLY-26104508
  • [Journal Article] リゾリン脂質と免疫制御 - 基礎から応用へ - (2) リゾホスファチジルセリン2015

    • Author(s)
      巻出久美子、青木淳賢
    • Journal Title

      炎症と免疫

      Volume: 22 Pages: 177-181

    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Journal Article] Lysophosphatidylserine has Bilateral Effects on Macrophages in the Pathogenesis of Atherosclerosis2015

    • Author(s)
      Nishikawa M, Kurano M, Ikeda H, Aoki J, Yatomi Y
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 22 Issue: 5 Pages: 518-526

    • DOI

      10.5551/jat.25650

    • NAID

      130004704381

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-15H05897, KAKENHI-PROJECT-25253040, KAKENHI-PROJECT-25293010
  • [Journal Article] Lysophosphatidic acid as a lipid mediator with multiple biological actions2015

    • Author(s)
      Aikawa S, Hashimoto T, Kano K, Aoki J
    • Journal Title

      J Biochem.

      Volume: 157 Issue: 2 Pages: 81089-81089

    • DOI

      10.1093/jb/mvu077

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Journal Article] Novel lysophosphoplipid receptors: their structure and function.2014

    • Author(s)
      Makide K, Uwamizu A, Shinjo Y, Ishiguro J, Okutani M, Inoue A, Aoki J.
    • Journal Title

      J. Lipid Res.

      Volume: 55 Issue: 10 Pages: 1986-95

    • DOI

      10.1194/jlr.r046920

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-25293010
  • [Journal Article] Regulation of intestinal IgA responses by dietary palmitic acid and its metabolism.2014

    • Author(s)
      Kunisawa J, Hashimoto E, Inoue A, Nagasawa R, Suzuki Y, Ishikawa I, Shikata S, Arita M, Aoki J, Kiyono H.
    • Journal Title

      J. Immunol.

      Volume: 193 Issue: 4 Pages: 1666-1671

    • DOI

      10.4049/jimmunol.1302944

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116006, KAKENHI-PROJECT-23229004, KAKENHI-PROJECT-24659217, KAKENHI-PUBLICLY-25116706, KAKENHI-PROJECT-26293111, KAKENHI-PROJECT-26670241
  • [Journal Article] Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin.2014

    • Author(s)
      Shimizu Y, Morikawa Y, Okudaira S, Kimoto S, Tanaka T, Aoki J, Tokumura A.
    • Journal Title

      Am. J. Pathol.

      Volume: 184 Issue: 5 Pages: 1593-1603

    • DOI

      10.1016/j.ajpath.2014.01.029

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Journal Article] 新しいGPCR活性化測定法“TGFα切断アッセイ”その発見の経緯と薬学研究における応用2014

    • Author(s)
      井上飛鳥、青木淳賢
    • Journal Title

      ファルマシア

      Volume: 50 Pages: 862-867

    • NAID

      130005245994

    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Journal Article] リゾホスファチジン酸産生酵素ATX/NPP2を標的とした創薬2014

    • Author(s)
      青木淳賢
    • Journal Title

      実験医学

      Volume: 32 Pages: 126-132

    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Journal Article] ENPP2 contributes to adipose tissue expansion and insulin resistance in diet-induced obesity.2014

    • Author(s)
      Nishimura S, Nagasaki M, Okudaira S, Aoki J, Ohmori T, Ohkawa R, Nakamura K, Igarashi K, Yamashita H, Eto K, Uno K, Hayashi N, Kadowaki T, Komuro I, Yatomi Y, Nagai R.
    • Journal Title

      Diabetes

      Volume: 63 Issue: 12 Pages: 4154-4164

    • DOI

      10.2337/db13-1694

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25253040, KAKENHI-PROJECT-26461356
  • [Journal Article] Prostaglandin E2 Inhibits Elastogenesis in the Ductus Arteriosus via EP4 Signaling.2014

    • Author(s)
      Yokoyama U, Minamisawa S, Sh ioda A, Ishiwata R, Jin MH, Masuda M, Asou T, Sugimoto Y, Aoki II, Nakamura T, and Ishikawa Y
    • Journal Title

      Circulation.

      Volume: 129 Issue: 4 Pages: 487-496

    • DOI

      10.1161/circulationaha.113.004726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01418, KAKENHI-PROJECT-14J01039, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116003, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24390334, KAKENHI-PROJECT-24659100, KAKENHI-PROJECT-24659640, KAKENHI-PUBLICLY-25116719, KAKENHI-PROJECT-25293236, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26293249, KAKENHI-PROJECT-26462114, KAKENHI-PROJECT-26670147, KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-26670621
  • [Journal Article] Prestwich GD. Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA) : metabolically stabilized LPA receptor agonists2013

    • Author(s)
      Jiang G, Inoue A, Aoki J
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 23 Issue: 6 Pages: 1865-9

    • DOI

      10.1016/j.bmcl.2013.01.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790064, KAKENHI-ORGANIZER-22116001
  • [Journal Article] Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function.2013

    • Author(s)
      Nakamura A, Ebina-Shibuya R, Itoh-Nakadai A, Muto A, Shima H, Saigusa D, Aoki J, Ebina M, Nukiwa T, Igarashi K.
    • Journal Title

      J Exp Med.

      Volume: 210 Issue: 11 Pages: 2191-2204

    • DOI

      10.1084/jem.20130028

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25860021
  • [Journal Article] Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin/lysophosphatidic acid axis2013

    • Author(s)
      Bai Z
    • Journal Title

      J. Immunology

      Volume: 190 Issue: 5 Pages: 2036-2048

    • DOI

      10.4049/jimmunol.1202025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590191, KAKENHI-PROJECT-22590440, KAKENHI-PROJECT-23790071, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-24590252, KAKENHI-PLANNED-21121007, KAKENHI-ORGANIZER-22116001
  • [Journal Article] GPR34 as a lysophosphatidylserine receptor2013

    • Author(s)
      Makide K and Aoki J
    • Journal Title

      J. Biochem.

      Volume: 153 Issue: 4 Pages: 327-329

    • DOI

      10.1093/jb/mvt010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Journal Article] TGFα shedding assay: an accurate and versatile method for detecting GPCR activation.2012

    • Author(s)
      Asuka Inoue
    • Journal Title

      Nat Methods

      Volume: 9 Issue: 10 Pages: 1021-1029

    • DOI

      10.1038/nmeth.2172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659025, KAKENHI-PROJECT-24659280, KAKENHI-PROJECT-24790064, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PUBLICLY-23112513
  • [Journal Article] Identification and biochemical characterization of a novel autotaxin isoform, ATXδ, with a four-amino acid deletion2012

    • Author(s)
      Hashimoto T, Okudaira S, Igarashi K, Hama K, Yatomi Y, Aoki J
    • Journal Title

      J Biochem

      Volume: 151 Issue: 1 Pages: 89-97

    • DOI

      10.1093/jb/mvr126

    • NAID

      10031166046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23790071
  • [Journal Article] Surface loops of extracellular phospholipase A(1)determine both substrate specificity and preference for lysophospholipids2012

    • Author(s)
      Arima N, Inoue A, Makide K, Nonaka T, Aoki J
    • Journal Title

      J Lipid Res

      Volume: 53 Pages: 513-521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position2012

    • Author(s)
      Kitamura H, Makide K, Shuto A, Ikubo M, Inoue A, Suzuki K, Sato Y, Nakamura S, Otani Y, Ohwada T, Aoki J
    • Journal Title

      J Biochem

      Volume: 151 Issue: 5 Pages: 511-518

    • DOI

      10.1093/jb/mvs011

    • NAID

      10031166091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-21770102, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23790006, KAKENHI-PROJECT-24659025
  • [Journal Article] Synthetic biotinylated peptide compounds derived from Asp-hemolysin : Novel potent inhibitors of platelet-activating factor2012

    • Author(s)
      Sato A, Kumagai T, Aoki J, Ebina K
    • Journal Title

      Eur J Pharmacol

      Volume: 685 Issue: 1-3 Pages: 205-212

    • DOI

      10.1016/j.ejphar.2012.04.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] The β9 Loop Domain of PA-PLA(1)α Has a Crucial Role in Autosomal Recessive Woolly Hair/Hypotrichosis2012

    • Author(s)
      Shinkuma S, Inoue A, Aoki J, Nishie W, Natsuga K, Ujiie H, Nomura T, Abe R, Akiyama M, Shimizu H
    • Journal Title

      The Journal of Investigative Dermatology

      Volume: (印刷中) Issue: 8 Pages: 2093-2095

    • DOI

      10.1038/jid.2012.96

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249063, KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23659546, KAKENHI-PROJECT-23791245, KAKENHI-PROJECT-24390152, KAKENHI-PROJECT-24659025, KAKENHI-PROJECT-24659526, KAKENHI-ORGANIZER-22116001
  • [Journal Article] Surface loops of extracellular phospholipase A(1) determine both substrate specificity and preference for lysophospholipids2012

    • Author(s)
      Arima N, Inoue A., et al
    • Journal Title

      J Lipid Res

      Volume: 53 Issue: 3 Pages: 513-521

    • DOI

      10.1194/jlr.m022400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J06237, KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-21770102, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013
  • [Journal Article] A missense mutation within the helix initiation motif of the keratin K71 gene underlies autosomal dominant woolly hair/hypotrichosis.2012

    • Author(s)
      Fujimoto A, Farooq M, Fujikawa H, Inoue A, Ohyama M, Ehama R, Nakanishi J, Hagihara M, Iwabuchi T, Aoki J, Ito M, Shimomura Y.
    • Journal Title

      J Invest Dermatol.

      Volume: 132 Issue: 10 Pages: 2342-2349

    • DOI

      10.1038/jid.2012.154

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22116001, KAKENHI-PUBLICLY-23116508
  • [Journal Article] A 3D view of autotaxin2012

    • Author(s)
      Nishimasu H, Ishitani R, Aoki J, Nureki O
    • Journal Title

      Trends Pharmacol Sci

      Volume: 33 Issue: 3 Pages: 138-145

    • DOI

      10.1016/j.tips.2011.12.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22117007, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-23687014
  • [Journal Article] The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice2012

    • Author(s)
      Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T, Sunden Y, Arai Y, Moriwaki K, Ishida J, Uemura A, Kiyonari H, Abe T, Fukamizu A, Hirashima M, Sawa H, Aoki J, Ishii M, Mochizuki N
    • Journal Title

      J Clin Invest

      Volume: 122 Pages: 1416-1426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice2012

    • Author(s)
      Fukuhara S, et al
    • Journal Title

      J Clin Invest

      Volume: (In press)(未定) Issue: 4 Pages: 1416-1426

    • DOI

      10.1172/jci60746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22113007, KAKENHI-PLANNED-22113009, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22390040, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-22689030, KAKENHI-PROJECT-22790891, KAKENHI-PROJECT-23300152, KAKENHI-PROJECT-24390204, KAKENHI-PROJECT-24659025
  • [Journal Article] Autotaxin as a novel serum marker of liver fibrosis2011

    • Author(s)
      Nakagawa H, Ikeda H, Nakamura K, Ohkawa R, Masuzaki R, Tateishi R, Yoshida H, Watanabe N, Tejima K, Kume Y, Iwai T, Suzuki A, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Omata M, Igarashi K, Aoki J, Koike K, Yatomi Y
    • Journal Title

      Clin Chim Acta

      Volume: 412 Issue: 13-14 Pages: 1201-1206

    • DOI

      10.1016/j.cca.2011.03.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013
  • [Journal Article] Specific increase in serum autotaxin activity in patients with pancreatic cancer2011

    • Author(s)
      Nakai Y, Ikeda H, Nakamura K, Kume Y, Fujishiro M, Sasahira N, Hirano K, Isayama H, Tada M, Kawabe T, Komatsu Y, Omata M, Aoki J, Koike K, Yatomi Y
    • Journal Title

      Clin Biochem

      Volume: 44 Issue: 8-9 Pages: 576-581

    • DOI

      10.1016/j.clinbiochem.2011.03.128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22590756, KAKENHI-PROJECT-22659013
  • [Journal Article] Serum autotaxin measurements in pregnant women : application for the differentiation of normal pregnancy and pregnancy-induced hypertension2011

    • Author(s)
      Masuda A, Fujii T, Iwasawa Y, Nakamura K, Ohkawa R, Igarashi K, Okudaira S, Ikeda H, Kozuma S, Aoki J, Yatomi Y
    • Journal Title

      Clin Chim Acta

      Volume: 412 Issue: 21-22 Pages: 1944-1950

    • DOI

      10.1016/j.cca.2011.06.039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23790071
  • [Journal Article] LPA-producing enzyme PA-PLA1a regulates hair follicle development by modulating EGFR signaling2011

    • Author(s)
      Inoue A., Arima N., et al
    • Journal Title

      EMBO J

      Volume: vol.30 Issue: 20 Pages: 4248-4260

    • DOI

      10.1038/emboj.2011.296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J06237, KAKENHI-PROJECT-21390015, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PUBLICLY-23113707, KAKENHI-PROJECT-23227004
  • [Journal Article] Crystal structure of autotaxin and insight into GPCR activation by lipid mediators2011

    • Author(s)
      Nishimasu H, Okudaira S, Hama K, Mihara E, Dohmae N, Inoue A, Ishitani R, Takagi J, Aoki J, Nureki O
    • Journal Title

      Nat Struct Mol Biol

      Volume: 18 Issue: 2 Pages: 205-212

    • DOI

      10.1038/nsmb.1998

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-ORGANIZER-22116001, KAKENHI-PROJECT-22247010, KAKENHI-PROJECT-22659013
  • [Journal Article] Fluorescence Probe for Lysophospholipase C/NPP6 Activity and a Potent NPP6 Inhibitor2011

    • Author(s)
      Mitsuyasu Kawaguchi, Takayoshi Okabe, Shinichi, Okudaira, Kenjiro Hanaoka, Yuuta Fujikawa, Takuya Terai, Toru Komatsu, Hirotatsu Kojima, Junken Aoki, Tetsuo Nagano
    • Journal Title

      Journal of the American Chemical Society

      Volume: 133 Issue: 31 Pages: 12021-12030

    • DOI

      10.1021/ja201028t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J10632, KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-22659013, KAKENHI-PROJECT-23790071
  • [Journal Article] Autotaxin regulates vascular development via multiple lysophosphatidic acid(LPA)receptors in zebrafish2011

    • Author(s)
      Yukiura H, Hama K, Nakanaga K, Tanaka M, Asaoka Y, Okudaira S, Arima N, Inoue A, Hashimoto T, Arai H, Kawahara A, Nishina H, Aoki J
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 51 Pages: 43972-43983

    • DOI

      10.1074/jbc.m111.301093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116004, KAKENHI-PROJECT-22659013, KAKENHI-PUBLICLY-23113707, KAKENHI-PUBLICLY-23118510, KAKENHI-PROJECT-23227004, KAKENHI-PROJECT-23390018, KAKENHI-PROJECT-23790071, KAKENHI-PROJECT-23790079
  • [Journal Article] Immunohistochemical detection of autotaxin (ATX)/lysophospholipase D (lysoPLD)in submucosal invasive colorectal cancer2011

    • Author(s)
      Kazama S, Kitayama J, Aoki J, Mori K, Nagawa H.
    • Journal Title

      J Gastrointest Cancer

      Volume: 42 Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Journal Article] Immunohistochemical detection of autotaxin(ATX)/lysophospholipase D(lysoPLD)in submucosal invasive colorectal cancer2011

    • Author(s)
      Kazama S, Kitayama J, Aoki J, Mori K, Nagawa H.
    • Journal Title

      J Gastrointest Cancer

      Volume: 42 Pages: 204-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid2010

    • Author(s)
      Hama K, Aoki J
    • Journal Title

      Prog Lipid Res (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice.2010

    • Author(s)
      Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H
    • Journal Title

      Cancer Lett 288

      Pages: 177-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Biological roles of lysophosphatidic acid signaling through its production by autotaxin.2010

    • Author(s)
      Okudaira S, Yukiura H, Aoki J
    • Journal Title

      Biochimie (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain2010

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Aoki J, Ueda H
    • Journal Title

      J Pharmacol Exp Ther 333(2)

      Pages: 540-546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain.2010

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Aoki J, Ueda H
    • Journal Title

      J Pharmacol Exp Ther. 333

      Pages: 540-546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] PA3, a unique G protein-coupled receptor for lysophosphatidic acid.2010

    • Author(s)
      Hama K, Aoki J
    • Journal Title

      Prog Lipid Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Adiponectin suppresses tumorigenesis in Apc(Min)(/+)mice2010

    • Author(s)
      Otani K, Kitayama J, Yasuda K, Nio Y, Iwabu M, Okudaira S, Aoki J, Yamauchi T, Kadowaki T, Nagawa H
    • Journal Title

      Cancer Lett

      Volume: 288 Issue: 2 Pages: 177-82

    • DOI

      10.1016/j.canlet.2009.06.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Expression of phosphatidylserine-specific phospholipase A(1)mRNA in human THP-1-derived macrophages2010

    • Author(s)
      Hosono H, Homma M, Ogasawara Y, Makide K, Aoki J, Niwata H, Watanabe M, Inoue K, Ohkohchi N, Kohda Y
    • Journal Title

      Cell Transplant

      Volume: 19 Pages: 759-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Journal Article] Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts2010

    • Author(s)
      David M, Wannecq E, Descotes F, Jansen S, Deux B, Ribeiro J, Serre CM, Gres S, Bendriss-Vermare N, Bollen M, Saez S, Aoki J, Saulnier-Blache JS, Clezardin P, Peyruchaud O
    • Journal Title

      PLoS One

      Volume: 17 Issue: 3 Pages: e9741-e9741

    • DOI

      10.1371/journal.pone.0009741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain2010

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Aoki J, Ueda H
    • Journal Title

      J Pharmacol Exp Ther 333(2)

      Pages: 540-546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis2010

    • Author(s)
      Shinkuma S, Akiyama M, Inoue A, Aoki J, Natsuga K, Nomura T, Arita K, Abe R, Ito K, Nakamura H, Ujiie H, Shibaki A, Suga H, Tsunemi Y, Nishie W, Shimizu H
    • Journal Title

      Hum Mutat

      Volume: 31 Pages: 602-10

    • DOI

      10.1002/humu.21235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22591215, KAKENHI-PROJECT-22659013
  • [Journal Article] Expression of phosphatidylserine-specific phospholipase A(1)mRNA in human THP-1-derived macrophages2010

    • Author(s)
      Hosono H, Homma M, Ogasawara Y, Makide K, Aoki J, Niwata H, Watanabe M, Inoue K, Ohkohchi N, Kohda Y
    • Journal Title

      Cell Transplant

      Volume: 19 Pages: 759-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine2010

    • Author(s)
      Nagai J, Uchida H, Matsushita Y, Yano R, Ueda M, Niwa M, Aoki J, Chun J, Ueda H
    • Journal Title

      Mol Pain

      Volume: 6 Pages: 78-78

    • DOI

      10.1186/1744-8069-6-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts.2010

    • Author(s)
      David M, Wannecq E, Descotes F, Jansen S, Deux B, Ribeiro J, Serre CM, Gres S, Bendriss-Vermare N, Bollen M, Saez S, Aoki J, Saulnier-Blache JS, Clezardin P, Peyruchaud O
    • Journal Title

      PLoS One 5

      Pages: 9741-9741

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid2010

    • Author(s)
      Hama K, Aoki J
    • Journal Title

      Prog Lipid Res (未定, In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA-PLA1alpha in autosomal recessive hypotrichosis.2010

    • Author(s)
      Shinkuma S, Akiyama M, Inoue A, Aoki J, Natsuga K, Nomura T, Arita K, Abe R, Ito K, Nakamura H, Ujiie H, Shibaki A, Suga H, Tsunemi Y, Nishie W, Shimizu H.
    • Journal Title

      Hum Mutat (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Development of an activity-based probe for autotaxin2010

    • Author(s)
      Cavalli S, Houben AJ, Albers HM, van Tilburg EW, de Ru A, Aoki J, van Veelen P, Moolenaar WH, Ovaa H
    • Journal Title

      Chembiochem

      Volume: 11 Issue: 16 Pages: 2311-2317

    • DOI

      10.1002/cbic.201000349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Evidence for de novo synthesis of lysophosphatidic acid in the spinal cord through phospholipase A2 and autotaxin in nerve injury-induced neuropathic pain2010

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Aoki J, Ueda H
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 333 Issue: 2 Pages: 540-546

    • DOI

      10.1124/jpet.109.164830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Biological roles of lysophosphatidic acid signaling through its production by autotaxin2010

    • Author(s)
      Okudaira S, Yukiura H, Aoki J
    • Journal Title

      Biochimie

      Volume: 92 Issue: 6 Pages: 698-706

    • DOI

      10.1016/j.biochi.2010.04.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015, KAKENHI-PROJECT-22659013
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome2009

    • Author(s)
      Makide, K., Kitamura, H., Sato, Y., Okutani, M., and Aoki, J.
    • Journal Title

      POLM (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.2009

    • Author(s)
      Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N,Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, Birchmeier C, Wiese S, Sendtner M,Kawabe H, Kishimoto-Suga M, Brose N, Baumgart J, Geist B, Aoki J, Savaskan NE, Brauer AU, Chun J,Ninnemann O, Schmitz D, Nitsch R.
    • Journal Title

      Cell 138

      Pages: 1222-1235

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid : an initiator of nerve injury-induced neuropathic pain2009

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Chun J, Aoki J, Ueda H
    • Journal Title

      Mol Pain 5

      Pages: 64-64

    • NAID

      120006984666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] merging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamineandlysophosphatidylglycerol.2009

    • Author(s)
      Makide K, Kitamura H, Sato Y, Okutani M, Aoki J
    • Journal Title

      Prostaglandins Other Lipid Mediat. 89

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome2009

    • Author(s)
      Makide, K., Kitamura, H., Sato, Y, Okutani, M., and Aoki, J
    • Journal Title

      POLM (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Expression of autotaxin and acylglycerol kinase in prostate cancer: association with cancer development and progression.2009

    • Author(s)
      Nouh MA, Wu XX, Okazoe H, Tsunemori H, Haba R, Abou-Zeid AM, Saleem MD, Inui M, Sugimoto M, Aoki J, Kakehi Y
    • Journal Title

      Cancer Sci. 100

      Pages: 1631-1638

    • NAID

      10027194307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice2009

    • Author(s)
      Endo, T., Kano, K., Motoki, R., Hama, K., Okudaira, S., Ishida, M., Ogiso, H., Tanaka, M., Matsuki, N., Taguchi, R., Kanai, M., Shibasaki, M., Arai, H., and Aoki. J.
    • Journal Title

      J. Biochem. In press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice2009

    • Author(s)
      Endo, T., Kano, K., Motoki, R., Hama, K., Okudaira, S., Ishida, M., Ogiso, H., Tanaka, M., Matsuki, N., Taguchi, R., Kanai, M., Shibasaki, M., Arai, H., and Aoki. J.
    • Journal Title

      J. Biochem (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome2009

    • Author(s)
      Makide, K., Kitamura, H., Sato, Y., Okutani, M., and Aoki, J
    • Journal Title

      POLM (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Expression of autotaxin, an ectoenzyme that produces lysophosphatidic acid, in human placenta.2009

    • Author(s)
      Iwasawa Y, Fujii T, Nagamatsu T, Kawana K, Okudaira S, Miura S, Matsumoto J, Tomio A, Hyodo H, Yamashita T, Oda K, Kozuma S, Aoki J, Yatomi Y, Taketani Y
    • Journal Title

      Am J Reprod Immunol. 62

      Pages: 90-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Intracellular phospholipase Algamma(iPLA1gamma)is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex2009

    • Author(s)
      Morikawa RK, Aoki J, et al.
    • Journal Title

      J Biol Chem 284(39)

      Pages: 26620-26630

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo2009

    • Author(s)
      Nakamura, K., Igarashi, K., Ohkawa, R., Okubo, S., Yokota, H., Kishimoto, T., Ide, K., Masuda, A., Yamamoto, T., Saito, N., Kurokawa, M., Tsuji, S., Okudaira, S., Ikeda, H., Aoki, J., and Yatomi, Y.
    • Journal Title

      J Biol. Chem (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Autotaxin enzyme immunoassay in human cerebrospinal fluid samples.2009

    • Author(s)
      Nakamura K, Ohkawa R, Okubo S, Yokota H, Ikeda H, Yatomi Y, Igarashi K, Ide K, Kishimoto T, Masuda A, Yamamoto T, Tsuji S, Saito N, Kurokawa M, Okudaira S, Aoki J
    • Journal Title

      Clin Chim Act 405

      Pages: 160-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol2009

    • Author(s)
      Makide K, Kitamura H, Sato Y, Okutani M, Aoki J
    • Journal Title

      Prostaglandins Other Lipid Mediat 89(3-4)

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo2009

    • Author(s)
      Nakamura, K., Igarashi, K., Ohkawa, R., Okubo, S., Yokota, H., Kishimoto, T., Ide, K., Masuda, A., Yamamoto, T., Saito, N., Kurokawa, M., Tsuji, S., Okudaira, S., Ikeda, H., Aoki, J., and Yatomi, Y.
    • Journal Title

      J. Biol. Chem. (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Lysophospliolipid mediators2009

    • Author(s)
      Makide K, Kano K, Kitamura H, Arima N, Aoki J.
    • Journal Title

      Tanpakushitsu Kakusan Koso 54

      Pages: 29-39

    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo2009

    • Author(s)
      Nakamura, K., Igarashi, K., Ohkawa, R., Okubo, S., Yokota, H., Kishimoto, T., Ide, K., Masuda, A., Yamamoto, T., Saito, N., Kurokawa, M., Tsuji, S., Okudaira, S., Ikeda, H., Aoki, J., and Yatomi, Y
    • Journal Title

      J. Biol. Chem (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice2009

    • Author(s)
      Endo, T., Kano, K., Motoki, R., Hama, K., Okudaira, S., Ishida, M., Ogiso, H., Tanalca,M., Matsuki, N., Taguchi, R., Kanai, M., Shibasaki, M., Arai, H., and Aoki, J.
    • Journal Title

      J. Biochem (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain.2009

    • Author(s)
      Ma L, Uchida H, Nagai J, Inoue M, Chun J, Aoki J, Ueda H.
    • Journal Title

      Mol Pain

      Pages: 5-64

    • NAID

      120006984666

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood.2009

    • Author(s)
      Endo T, Kano K, Motoki R, Hama K, Okudaira S, Ishida M, Ogiso H, Tanaka M, Matsuki N, Taguchi R, Kanai M, Shibasaki M, Arai H, Aoki J
    • Journal Title

      J Biochem. 146

      Pages: 283-93

    • NAID

      10026303013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation2008

    • Author(s)
      Nakamura, K., K. Igarashi, K. Ide, R. Ohkawa, S. Okubo, H. Yokota, A. Masuda, N. Oshima, T. Takeuchi, M. Nangaku, S. Okudaira, H. Arai, H. Ikeda, Aoki J,and Y. Yatomi
    • Journal Title

      Clin.Chim.Acta. 388

      Pages: 51-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and itsapplication to hypoalbuminemia differentiation.2008

    • Author(s)
      Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chim. Acta 388

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Autotaxin, a synthetic enzyme of lysophosphatidic acid(LPA), mediates the induction of nerve-injured neuropathic pain2008

    • Author(s)
      Inoue M, Ma L, Aoki J, Chun J, Ueda H.
    • Journal Title

      Mol Pain 4

      Pages: 6-6

    • NAID

      120006982424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation.2008

    • Author(s)
      Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H. Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chim. Acta 388

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome.2008

    • Author(s)
      Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chem. Lab. Med. 46

      Pages: 150-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Beta-catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions2008

    • Author(s)
      Kanamori T, Inoue T, Sakamoto T, Gengyo-Ando K, Tsujimoto M, Mitani S, Sawa H, Aoki J, and Arai H.
    • Journal Title

      EMBO J. 27

      Pages: 1647-1657

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo.2008

    • Author(s)
      Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1628-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Phospholipase A(1) assays using a radiolabeled substrate and mass spectrometry2008

    • Author(s)
      Ohuchi, H., Hamada, A., Matsuda, H., Takagi, A., Tanaka, M., Aoki, J., Arai, H., and Noji, S.
    • Journal Title

      Dev. Dyn 237

      Pages: 3280-3294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation2008

    • Author(s)
      Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H, Aoki J, Yatomi Y
    • Journal Title

      Clin Chim Acta 388

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A (1) assays using a radiolabeled substrate and mass spectrometry2008

    • Author(s)
      Ohuchi, H., Hamada, A., Matsuda, H., Takagi, A., Tanaka, M., Aoki, J., Arai, H., and Noii, S.
    • Journal Title

      Dev. Dyn. 237

      Pages: 3280-3294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation.2008

    • Author(s)
      Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin, Chim. Acta 388

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type IIPAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo.2008

    • Author(s)
      Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1628-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker : study on prostate cancer patients2008

    • Author(s)
      Nakasaki, T., Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., and Miyasaka, M
    • Journal Title

      Am J pathol 173

      Pages: 1566-1576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions Am2008

    • Author(s)
      Nakasaki T, Tanaka T, Okudaira S, Hirosawa M, Umemoto E, Otani K, Jin S, Bai Z, Hayasaka H, Fukui Y, Aozasa K, Fujita N, Tsuruo T, Ozono K, Aoki J and Miyasaka M
    • Journal Title

      J. Pathol 237

      Pages: 3280-3294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo.2008

    • Author(s)
      Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1628-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation2008

    • Author(s)
      Makide, K., Kano, K., Kitamura, H., Arima, N., and Aoki, J
    • Journal Title

      Tanpakushitsu Kakusan Koso 54

      Pages: 29-39

    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome2008

    • Author(s)
      Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y
    • Journal Title

      Clin Chem Lab Med. 46

      Pages: 150-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human samples and its application to hypoalbuminemia differentiation.2008

    • Author(s)
      Nakamura K, Igarashi K, Ide K, Ohkawa R, Okubo S, Yokota H, Masuda A, Oshima N, Takeuchi T, Nangaku M, Okudaira S, Arai H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chim. Acta 388

      Pages: 51-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation2008

    • Author(s)
      Makide, K., Kano, K., Kitamura, H., Arima. N.. and Aoki. J.
    • Journal Title

      Tanpakushitsu Kakusan Koso 54

      Pages: 29-39

    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker : study on prostate cancer patients2008

    • Author(s)
      Nakasaki, T., Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y, Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., and Miyasaka, M.
    • Journal Title

      Am J Pathol 173

      Pages: 1566-1576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A(1) assays using a radiolabeled substrate and mass spectrometry2008

    • Author(s)
      Ohuchi, H., Hamada, A., Matsuda, H., Takagi, A., Tanaka, M., Aoki, J., Arai, H., and Noii, S
    • Journal Title

      Dev. Dyn 237

      Pages: 3280-3294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome.2008

    • Author(s)
      Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chem. Lab. Med. 46

      Pages: 150-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome.2008

    • Author(s)
      Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chem. Lab. Med. 46

      Pages: 150-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum autotaxin measurement in haematological malignancies : a promising marker for follicular lymphoma2008

    • Author(s)
      Masuda A, Nakamura K, Izutsu K, Igarashi K, Ohkawa R, Jona M, Higashi K, Yokota H, Okudaira S, Kishimoto T, Watanabe T, Koike Y, Ikeda H, Kozai Y, Kurokawa M, Aoki J, Yatomi Y
    • Journal Title

      Br J Haematol 143

      Pages: 60-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Expression patterns of the lysophospholipid receptor genes during mouse early development2008

    • Author(s)
      Ohuchi H, Hamada A, Matsuda H, Takagi A, Tanaka M, Aoki J, Arai H, Noji S.
    • Journal Title

      Dev Dyn. 237

      Pages: 3280-3294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] LPA and its analogs-attractive tools for elucidation of LPA biology and drug development(review)2008

    • Author(s)
      Kano K, Arima N, Ohgami M, and Aoki J
    • Journal Title

      Curr.Med.Chem. 15

      Pages: 2122-2131

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker : study on prostate cancer patients2008

    • Author(s)
      Nakasaki, T., Tanaka, T., Okudaira, S., Hirosawa, M., Umemoto, E., Otani, K., Jin, S., Bai, Z., Hayasaka, H., Fukui, Y., Aozasa, K., Fujita, N., Tsuruo, T., Ozono, K., Aoki, J., and Miyasaka, M.
    • Journal Title

      Am J Pathol. 173

      Pages: 1566-1576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome.2008

    • Author(s)
      Nakamura K, Nangaku M, Ohkawa R, Okubo S, Yokota H, Ikeda H, Aoki J, Yatomi Y.
    • Journal Title

      Clin. Chem. Lab. Med. 46

      Pages: 150-151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX-mediated conversion to LPA,an initiator of neuropathic pain2008

    • Author(s)
      Inoue M, Ma L, Aoki J, Ueda H.
    • Journal Title

      J Neurochem. 107

      Pages: 1556-1565

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo.2008

    • Author(s)
      Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 1628-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hvnoalbuminemia differentiation2008

    • Author(s)
      Makide, K., Kano, K., Kitamura, H., Arima, N., and Aoki, I
    • Journal Title

      Tanpakushitsu Kakusan Koso 54

      Pages: 29-39

    • Data Source
      KAKENHI-PROJECT-20013005
  • [Journal Article] Two pathways for lysophosphatidic acid production(review)2008

    • Author(s)
      Aoki J, Inoue A,and Okudaira S.
    • Journal Title

      Biochim.Biophys.Acta. 1781

      Pages: 513-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Protection against oxidative stress-induced hepatic injury by intracellular type II platelet-activating factor acetylhydrolase by metabolism of oxidized phospholipids in vivo2008

    • Author(s)
      Kono N, Inoue T, Yoshida Y, Sato H, Matsusue T, Itabe H, Niki E, Aoki J, Arai H
    • Journal Title

      J.Biol.Chem. 283

      Pages: 1628-1636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A(1)assays using a radiolabeled substrate and mass spectrometry.2007

    • Author(s)
      Morikawa R, Tsujimoto M, Arai H, Aoki J.
    • Journal Title

      Methods Enzymol. 434

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD).2007

    • Author(s)
      Mori K, Kitayama J, Aoki J, Kishi Y, Shida D, Yamashita H, Arai H, Nagawa H.
    • Journal Title

      Virchows Arch. 451

      Pages: 47-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.2007

    • Author(s)
      Yamaguchi N, Koizumi H, Aoki J, Natori Y, Nishikawa K, Natori Y, Takanezawa Y, Arai H.
    • Journal Title

      Genes Cells 12

      Pages: 1153-1161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD).2007

    • Author(s)
      Mori K, Kitayama J, Aoki J, Kishi Y, Shida D, Yamashita H, Arai H, Nagawa H.
    • Journal Title

      Virchows Arch. 451

      Pages: 47-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liverinjury in rats in relation to its severity.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M, Fujiwara K, Yatomi Y.
    • Journal Title

      Life Sci. 81

      Pages: 1009-1015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice.2007

    • Author(s)
      Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, Ye X, Chun J, Matsuki N, Suzuki H, Shibasaki M, Arai H.
    • Journal Title

      Biol. Reprod. 77

      Pages: 954-959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.2007

    • Author(s)
      Satoh Y, Ohkawa R, Nakamura K, Higashi K, Kaneko M, Yokota H, Aoki J, Arai H, Yuasa Y, Yatomi Y.
    • Journal Title

      Eur. J. Haematol. 78

      Pages: 510-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Autotaxin (NPP-2) in the brain: Cell type-specific expression and regulation during development and after neurotrauma2007

    • Author(s)
      Savaskan NE, Rocha L, Kotter MR, Lubec G, Baer A, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WH, Nitsch R, Brauer AU.
    • Journal Title

      Cell. Mol. Life Sci. 64

      Pages: 230-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity.2007

    • Author(s)
      Tokumura A, Kume T, Fukuzawa K, Tahara M, Tasaka K, Aoki J, Arai H
    • Journal Title

      Life Sci. 80

      Pages: 1641-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Structure and function of extracellular phospholipase Al belonging to the pancreatic lipase gene family (review).2007

    • Author(s)
      Aoki J, Inoue A, Makide K, Saiki N, Arai H.
    • Journal Title

      Biochimie 89

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice.2007

    • Author(s)
      Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, YeX, Chun J, Matsuki N, Suzuki H, Shibasaki M, Arai H.
    • Journal Title

      Biol. Reprod. 77

      Pages: 954-959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Autotaxin (NPP-2) in the brain: Cell type-specific expression and regulation during development and after neurotrauma2007

    • Author(s)
      Savaskan NE, Rocha L, Kotter MR, Lubec G, Baer A, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WH, Nitsch R, Brauer AU.
    • Journal Title

      Cell. Mol. Life Sci. 64

      Pages: 230-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Phospholipase A(1) assays using a radiolabeled substrate and mass spectrometry2007

    • Author(s)
      Morikawa, R., M. Tsujimoto, H. Arai,and Aoki J.
    • Journal Title

      Methods Enzymol 434

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzymeduring mouse and chicken development.2007

    • Author(s)
      Ohuchi H, Hayashibara Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S.
    • Journal Title

      Dev. Dyn. 236

      Pages: 1134-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Plasma lysophosphatidic acid is increased in liver fibrosis in rats and human with enhanced serum autotaxin level.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Aoki J, Hama K, Okudaira S, Tanaka M, Yanase M, Nagashima K, Tomiya T, Arai M, Inoue Y, Tejima K, Nishikawa T, Arai H, Omata M, Fujiwara K, Yatomi Y
    • Journal Title

      J. Clin. Gastroenterol 41

      Pages: 616-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A (1) assays using a radiolabeled substrate and mass spectrometry.2007

    • Author(s)
      Morikawa R, Tsujimoto M, Arai H, Aoki J.
    • Journal Title

      Methods Enzymol. 434

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Structure and function of extracellular phospholipase A(1) belonging to the pancreatic lipase gene family2007

    • Author(s)
      Aoki, J., A. Inoue, K. Makide, N. Saiki,and H. Arai
    • Journal Title

      Biochimie 89

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.2007

    • Author(s)
      Yamaguchi N, Koizumi H, Aoki J, Natori Y, Nishikawa K, Natori Y, Takanezawa Y, Arai H.
    • Journal Title

      Genes Cells 12

      Pages: 1153-1161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.2007

    • Author(s)
      Nakamura K, Takeuchi T, Ohkawa R, Okubo S, Yokota H, Tozuka M, Aoki J, Arai H, Ikeda H, Ohshima N, Kitamura T, Yatomi Y.
    • Journal Title

      Ann. Clin. Biochem. 44

      Pages: 549-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A(1)assays using a radiolabeled substrate and mass spectrometry.2007

    • Author(s)
      Morikawa R, Tsujimoto M, Arai H, Aoki J.
    • Journal Title

      Methods Enzymol. 434

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Neuroprotective Role of Transgenic PAF-Acetylhydrolase II in Mouse Models of Focal Cerebral Ischemia.2007

    • Author(s)
      Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K.
    • Journal Title

      Stroke 38

      Pages: 1036-1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development2007

    • Author(s)
      Ohuchi, H., Y. Hayashibaral, H. Matsuda, M. Onoi, M. Mitsumori, M. Tanaka, Aoki J, H. Arai,and S. Noji
    • Journal Title

      Dev.Dyn. 236

      Pages: 1134-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Neuroprotective Role of Transgenic PAF-Acetylhydrolase II in Mouse Modele of Focal Cerebral Ischemia.2007

    • Author(s)
      Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K.
    • Journal Title

      Stroke 38

      Pages: 1036-1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Measurement of lysophospholipase D/autotaxin activity in human serum samples2007

    • Author(s)
      Nakamura K, Ohkawa R, Okubo S, Tozuka M, Okada M, Aoki S, Aoki J, Arai H, Ikeda H, Yatomi Y
    • Journal Title

      Clin. Biochem. 40

      Pages: 274-277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice.2007

    • Author(s)
      Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, Ye X, Chun J, Matsuki N, Suzuki H, Shibasaki M, Arai H.
    • Journal Title

      Biol. Reprod 77

      Pages: 954-959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Measurement of lysophospholipase D/autotaxin activity in human serum samples2007

    • Author(s)
      Nakamura K, Ohkawa R, Okubo S, Tozuka M, Okada M, Aoki S, Aoki J, Arai H, Ikeda H, Yatomi Y
    • Journal Title

      Clin. Biochem. 40

      Pages: 274-277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Phospholipase A1-structure, distribution and function-2007

    • Author(s)
      Inoue, A.,and Aoki, J.
    • Journal Title

      Future Lipidology 1

      Pages: 699-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice.2007

    • Author(s)
      Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, Ye X, Chun J, Matsuki N, Suzuki H, Shibasaki M, Arai H.
    • Journal Title

      Biol. Reprod. 77

      Pages: 954-959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Neuroprotective Role of Transgenic PAF-Acetylhydrolase II in Mouse Models of Focal Cerebral Ischemia.2007

    • Author(s)
      Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K.
    • Journal Title

      Stroke 38

      Pages: 1036-1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Type I platelet-activating factor acetylhydrolase catalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.2007

    • Author(s)
      Yamaguchi N, Koizumi H, Aoki J, Natori Y, Nishikawa K, Natori Y, Takanezawa Y, Arai H.
    • Journal Title

      Genes Cells 12

      Pages: 1153-1161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity.2007

    • Author(s)
      Tokumura A, Kume T, Fukuzawa K, Tahara M, Tasaka K, Aoki J, Arai H
    • Journal Title

      Life Sci. 80

      Pages: 1641-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.2007

    • Author(s)
      Satoh Y, Ohkawa R, Nakamura K, Higashi K, Kaneko M, Yokota H, Aoki J, Arai H, Yuasa Y, Yatomi Y.
    • Journal Title

      Eur. J. Haematol. 78

      Pages: 510-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX) /lysophospholipase D (lysoPLD).2007

    • Author(s)
      Mori K, Kitayama J, Aoki J, Kishi Y, Shida D, Yamashita H, Arai H, Nagawa H.
    • Journal Title

      Virchows Arch. 451

      Pages: 47-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M, Fujiwara K, Yatomi Y.
    • Journal Title

      Life Sci. 81

      Pages: 1009-1015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Plasma lysophosphatidic acid is increased in liver fibrosis in rats and human with enhanced serum autotaxin level.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Aoki J, Hama K, Okudaira S, Tanaka M, Yanase M, Nagashima K, Tomiya T, Arai M, Inoue Y, Tejima K, Nishikawa T, Arai H, Omata M, Fujiwara K, Yatomi Y
    • Journal Title

      J. Clin. Gastroenterol 41

      Pages: 616-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Plasma lySophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M, Fujiwara K, Yatomi Y.
    • Journal Title

      Life Sci. 81

      Pages: 1009-1015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice2007

    • Author(s)
      Hama, K., Aoki J., A. Inoue, T. Endo, T. Amano, R. Motoki, M. Kanai, X. Ye, J. Chun, N. Matsuki, H. Suzuki, M. Shibasaki,and H. Arai
    • Journal Title

      Biol.Reprod 77

      Pages: 954-959

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid(LPA)in the gastrointestinal tract through the secretion of autotaxin(ATX)/lysophospholipase D(lysoPLD)2007

    • Author(s)
      Mori, K., J. Kitayama, Aoki, J. Y. Kishi, D. Shida, H. Yamashita, H. Arai,and H. Nagawa
    • Journal Title

      Virchows Arch. 451

      Pages: 47-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Plasma lysophosphatidic acid is increased in Iiver fibrosis in rats and human with enhanced serum autotaxin level.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, AokiJ, Hama K, Okudaira S, Tanaka M, Yanase M, Nagashima K, Tomiya T, Arai M, Inoue Y, Tejima K, Nishikawa T, Arai H, Omata M, Fujiwara K, Yatomi Y
    • Journal Title

      J. Clin. Gastroenterol 41

      Pages: 616-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.2007

    • Author(s)
      Nakamura K, Takeuchi T, Ohkawa R, Okubo S, Yokota H, Tozuka M, Aoki J, Arai H, Ikeda H, Ohshima N, Kitamura T, Yatomi Y.
    • Journal Title

      Ann. Clin. Biochem. 44

      Pages: 549-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.2007

    • Author(s)
      Satoh Y, Ohkawa R, Nakamura K, Higashi K, Kaneko M, Yokota H, Aoki J, Arai H, Yuasa Y, Yatomi Y.
    • Journal Title

      Eur. J. Haematol. 78

      Pages: 510-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Type I platelet-activating factor acetylhydrolase calalytic subunits over-expression induces pleiomorphic nuclei and centrosome amplification.2007

    • Author(s)
      Yamaguclu N, Koizumi H, Aoki J, Natori Y, Nishikawa K, Natori Y, Takanezawa Y, Arai H.
    • Journal Title

      Genes Cells 12

      Pages: 1153-1161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Diversified expression patterns of autotaxin, gene for phospholipid-generating enzyme during mouse and chicken development.2007

    • Author(s)
      Ohuchi H, Hayashibara Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S.
    • Journal Title

      Dev. Dyn. 236

      Pages: 1134-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.2007

    • Author(s)
      Nakamura K, Takeuchi T, Ohkawa R, Okubo S, Yokota H, Tozuka M, Aoki J, Arai H, Ikeda H, Ohshima N, Kitamura T, Yatomi Y.
    • Journal Title

      Ann. Clin. Biochem. 44

      Pages: 549-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity.2007

    • Author(s)
      Tokumura A, Kume T, Fukuzawa K, Tahara M, Tasaka K, Aoki J, Arai H
    • Journal Title

      Life Sci. 80

      Pages: 1641-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family (review).2007

    • Author(s)
      Aoki J, Inoue A, Makide K, Saiki N, Arai H.
    • Journal Title

      Biochimie 89

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Autotaxin (NPP-2) in the brain: Cell type-specific expression and regulation during development and after neurotrauma2007

    • Author(s)
      Savaskan NE, Rocha L, Kotter MR, Lubec G, Baer A, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WH, Nitsch R, Brauer AU.
    • Journal Title

      Cell. Mol. Life Sci. 64

      Pages: 230-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Neuroprotective Role of Transgenic PAF-Acetylhydrolase II in Mouse Models of Focal Cerebral Ischemia.2007

    • Author(s)
      Umemura K, Kato I, Hirashima Y, Ishii Y, Inoue T, Aoki J, Kono N, Oya T, Hayashi N, Hamada H, Endo S, Oda M, Arai H, Kinouchi H, Hiraga K.
    • Journal Title

      Stroke 38

      Pages: 1036-1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid(LPA)in the gastrointestinal tract through the secretion of autotaxin(ATX)/lysophospholipase D(lysoPLD).2007

    • Author(s)
      Mori K, Kitayama J, Aoki J, Kishi Y, Shida D, Yamashita H, Arai H, Nagawa H.
    • Journal Title

      Virchows Arch. 451

      Pages: 47-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels ofbioactive lysophospholipase D activi2007

    • Author(s)
      Tokumura A, Kume T, Fukuzawa K, Tahara M, Tasaka K, Aoki J, Arai H
    • Journal Title

      Life Sci. 80

      Pages: 1641-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients.2007

    • Author(s)
      Nakamura K, Takeuchi T, Ohkawa R, Okubo S, Yokota H, Tozuka M, Aoki J, Arai H, Ikeda H, Ohshima N, Kitamura T, Yatomi Y.
    • Journal Title

      Ann. Clin. Biochem. 44

      Pages: 549-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Plasma lysophosphatidic acid is increased in liver fibrosis in rats and human with enhanced serum autotaxin level.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Aoki J, Hama K, Okudaira S, Tanaka M, Yanase M, Nagashima K, Tomiya T, Arai M, Inoue Y, Tejima K, Nishikawa T, Arai H, Omata M, Fujiwara K, Yatomi Y
    • Journal Title

      J. Clin. Gastroenterol 41

      Pages: 616-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Structure and function of extracellular phospholipase Al belonging to the pancreatic lipase gene family (review).2007

    • Author(s)
      Aoki J, Inoue A, Makide K, Saiki N, Arai H.
    • Journal Title

      Biochimie 89

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Measurement of lysophospholipase D/autotaxin activity in human serum samples2007

    • Author(s)
      Nakamura K, Ohkawa R, Okubo S, Tozuka M, Okada M, Aoki S, Aoki J, Arai H, Ikeda H, Yatomi Y
    • Journal Title

      Clin. Biochem. 40

      Pages: 274-277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Measurement of lysophospholipase D/autotaxin activity in human serum samples2007

    • Author(s)
      Nakamura K, Ohkawa R, Okubo S, Tozuka M, Okada M, Aoki S, Aoki J, Arai H, Ikeda H, Yatomi Y
    • Journal Title

      Clin. Biochem. 40

      Pages: 274-277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Structure and function of extracellular phospholipase Al belonging to the pancreatic lipase gene family(review).2007

    • Author(s)
      AokiJ, Inoue A, Makide K, Saiki N, Arai H.
    • Journal Title

      Biochimie 89

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzymeduring mouse and chicken development.2007

    • Author(s)
      Ohuchi H, Hayashibara Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S.
    • Journal Title

      Dev. Dyn. 236

      Pages: 1134-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Autotaxin(NPP-2)in the brain: Cell type-specific expression and regulation during development and after neurotrauma2007

    • Author(s)
      Savaskan NE, Rocha L, Kotter MR, Lubec G, Baer A, van Meeteren LA, Kishi Y, Aoki J, Moolenaar WH, Nitsch R, Brauer AU.
    • Journal Title

      Cell. Mol. Life Sci. 64

      Pages: 230-243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Journal Article] Lysophosphatidic acid protection against apoptosis in the human pre-B-cell line Nalm-6.2007

    • Author(s)
      Satoh Y, Ohkawa R, Nakamura K, Higashi K, Kaneko M, Yokota H, Aoki J, Arai H, Yuasa Y, Yatomi Y.
    • Journal Title

      Eur. J. Haematol. 78

      Pages: 510-517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Phospholipase A (1) assays using a radiolabeled substrate and mass spectrometry.2007

    • Author(s)
      Morikawa R, Tsujimoto M, Arai H, Aoki J.
    • Journal Title

      Methods Enzymol. 434

      Pages: 1-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18013018
  • [Journal Article] Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity.2007

    • Author(s)
      Watanabe N, Ikeda H, Nakamura K, Ohkawa R, Kume Y, Tomiya T, Tejima K, Nishikawa T, Arai M, Yanase M, Aoki J, Arai H, Omata M, Fujiwara K, Yatomi Y.
    • Journal Title

      Life Sci 81

      Pages: 1009-1015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050009
  • [Journal Article] Diversified expression patterns of autotaxin, a gene for phospholipid-generating enzyme during mouse and chicken development2007

    • Author(s)
      Ohuchi H, Hayashibaza Y, Matsuda H, Onoi M, Mitsumori M, Tanaka M, Aoki J, Arai H, Noji S.
    • Journal Title

      Dev. Dyn. 236

      Pages: 1134-1143

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Journal Article] Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus2006

    • Author(s)
      Kotaro Hama, Junken Aoki, Koji Bandoh, Asuka Inoue, Tomoko Endo, Tomokazu Amano, Hiroshi Suzuki, Hiroyuki Arai
    • Journal Title

      Life Sciences 79

      Pages: 1736-1740

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcoholine to lysophosphatidic acid.2006

    • Author(s)
      Kishi Y, Okudaira S, Tanaka M, Hama K, Shida D, Kitayama J, Yamori T, Aoki J, Fujimaki T, Arai H.
    • Journal Title

      J.Biol.Chem. 281

      Pages: 17492-17500

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] Transgenic Expression of Group V, but not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality due to Lung Dysfunction2006

    • Author(s)
      M.Ohtsuki, Y.Taketomi, S.Arata, S.Masuda, Y.Ishikawa, T.Ishii, Y.Takanezawa, J.Aoki, H.Arai, K.Yamamoto, I.Kudo, M.Murakami
    • Journal Title

      J.Biol.Chem. 281

      Pages: 36420-36433

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid2006

    • Author(s)
      Masayuki Tanaka, Shinichi Okudaira, Yasuhiro Kishi, Ryunosuke Ohkawa, Sachiko Iseki, Masato Ota, Sumihare Noji, Yutaka Yatomi, Junken Aoki, Hiroyuki Arai
    • Journal Title

      J.Biol.Chem. 281

      Pages: 25822-25830

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] Phospholipase Als -Structure, distribution and function- (review)2006

    • Author(s)
      Asuka Inoue, Junken Aoki
    • Journal Title

      Future Lipidology 1

      Pages: 687-700

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] Cyclic phosphatidic acid is produced by autotaxin in blood2006

    • Author(s)
      Satomi Tsuda, Shinichi Okudaira, Keiko Moriya-Ito, Chie Shimamoto, Masayuki Tanaka, Junken Aoki, Hiroyuki Arai, Kimiko Murakami-Murofushi, Tetsuyuki Kobayashi
    • Journal Title

      J.Biol.Chem. 281

      Pages: 26081-26088

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390016
  • [Journal Article] LPA3-mediated lysophosphatidic acid signalling in implantation.and embryo spacing2005

    • Author(s)
      Tomokazu Amano, Grace Kennedy, Hiroyuki Arai, Junken Aoki, Jerald Chun
    • Journal Title

      Nature 435

      Pages: 104-108

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.2004

    • Author(s)
      Hama K, Aoki J, Fukaya M, Kishi Y, Sakai T, Suzuki R, Ohta H, Yamori T, Watanabe M, Chun J, Arai H.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 17634-17639

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Mechanisms of lysophosphatidic acid production (review).2004

    • Author(s)
      Junken Aoki
    • Journal Title

      Semin.Cell Dev.Biol. 15

      Pages: 477-489

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Prostatic acid Phosphatase Degrades Lysophosphatidic Acid in Seminal Plasma2004

    • Author(s)
      Masayuki Tanaka, Yasuhiro Kishi, Yasukazu Takanezawa, Yoshiyuki Kakehi, Junken Aoki, Hiroyuki Arai
    • Journal Title

      FEBS Lett. 571

      Pages: 197-204

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in C.elegans2004

    • Author(s)
      Takao Inoue, Asako Sugimoto, Yuka Suzuki, Masayuki Yamamoto, Masafumi Tsujimoto, Junken Aoki, Hiroyuki Arai
    • Journal Title

      Proc.Natl.Acad.Sci. 101

      Pages: 13233-13238

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Mechanisms of lysophosphatidic acid production2004

    • Author(s)
      Aoki, J.
    • Journal Title

      Semin.Cell Dev.Biol. 15

      Pages: 477-489

    • NAID

      10011214554

    • Data Source
      KAKENHI-PROJECT-16022215
  • [Journal Article] Identifying Specific Conformations by Using a Carbohydrate Scaffold : Discovery of Subtype-Selective LPA-Receptor Agonists and an Antagonist.2004

    • Author(s)
      Tamaruya Y, Suzuki M, Kamura G, Kanai M, Hama K, Shimizu K, Aoki J, Arai H, Shibasaki M.
    • Journal Title

      Angew.Chem.Int.Ed.Engl. 43

      Pages: 2834-2837

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Journal Article] Mechanisms of lysophosphatidic acid production2004

    • Author(s)
      Aoki, J.
    • Journal Title

      Semin.Cell Dev.Biol. 15

      Pages: 477-489

    • NAID

      10011214554

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15370052
  • [Patent] Gタンパク質共役型受容体シグナルの伝達の検出方法2014

    • Inventor(s)
      井上飛鳥、青木淳賢
    • Industrial Property Rights Holder
      東北大学、東ソー
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-513383
    • Filing Date
      2014-03-18
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Patent] オートタキシンアイソフォームδ及びεの測定による疾患等の検出方法2013

    • Inventor(s)
      青木淳賢、島本怜史、五十嵐 浩二
    • Industrial Property Rights Holder
      東北大学、東ソー
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-208050
    • Filing Date
      2013-10-02
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Patent] オートタキシンアイソフォームα、β及びγの測定による疾患等の検出方法2013

    • Inventor(s)
      青木淳賢、島本怜史、五十嵐 浩二
    • Industrial Property Rights Holder
      東北大学、東ソー
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-208049
    • Filing Date
      2013-10-03
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Patent] 自己免疫疾患治療薬のスクリーニング方法2011

    • Inventor(s)
      青木淳賢、巻出久美子、井上飛鳥、大和田智彦、井久保仁也、尾谷優子
    • Industrial Property Rights Holder
      東北大学、東京大学
    • Industrial Property Number
      2011-112881
    • Filing Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Patent] オートタキシンアイソフォーム特異的抗体および検出方法2011

    • Inventor(s)
      青木淳賢、五十嵐浩二
    • Industrial Property Rights Holder
      株式会社東ソー、東北大学
    • Industrial Property Number
      2011-150054
    • Filing Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Patent] 自己免疫疾患治療薬のスクリーニング方法2011

    • Inventor(s)
      青木淳賢、巻出久美子、井上飛鳥、大和田智彦、井久保仁也、尾谷優子
    • Industrial Property Rights Holder
      東北大学、東京大学
    • Industrial Property Number
      2011-112881
    • Filing Date
      2011-05-29
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Patent] オートタキシンアイソフォーム特異的抗体および検出方法2011

    • Inventor(s)
      青木淳賢、五十嵐浩二
    • Industrial Property Rights Holder
      株式会社東ソー、東北大学
    • Industrial Property Number
      2011-150054
    • Filing Date
      2011-07-06
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Patent] P2Y10またはGPR174を使用して、リゾホスファチジルセリン受容体への被検化合物のアゴニスト活性またはアンタゴニスト活性を評価することを含む、自己免疫疾患の治療剤または予防剤のスクリーニング方法2011

    • Inventor(s)
      青木淳賢, 他
    • Industrial Property Rights Holder
      青木淳賢, 他
    • Industrial Property Number
      2011-112881
    • Filing Date
      2011-05-19
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Patent] 自己免疫疾患治療薬のスクリーニング方法2011

    • Inventor(s)
      青木淳賢、巻出久美子、井上飛鳥、大和田智彦
    • Industrial Property Rights Holder
      東北大学、東京大学
    • Industrial Property Number
      2011-112881
    • Filing Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Patent] ホスファチジルセリン特異的ホスホリパーゼA1測定による全身性エリテマトーデスの検査方法および検査薬2010

    • Inventor(s)
      沢田哲治、矢冨裕、中村和宏、青木淳賢、五十嵐浩二
    • Industrial Property Rights Holder
      株式会社東ソー、東京大学、東北大学
    • Industrial Property Number
      2010-172068
    • Filing Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Patent] ホスファチジルセリン特異的ホスホリパーゼA1測定による全身性エリテマトーデスの検査方法および検査薬2010

    • Inventor(s)
      沢田哲治、矢冨裕、中村和宏、青木淳賢、五十嵐浩二
    • Industrial Property Rights Holder
      株式会社東ソー、東京大学、東北大学
    • Industrial Property Number
      2010-172068
    • Filing Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Presentation] PS-PLA1-LysoPS軸の感染症免疫における機能解析2022

    • Author(s)
      柳沼 舜, 近江 純平, 可野 邦行, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] LysoPS受容体サブタイプ選択的アゴニストを使用したLPS2のB細胞上機能の解析2022

    • Author(s)
      上水 明治, 大和田 智彦, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] リン脂質研究における新たな質量分析イメージング法の開発とその応用2021

    • Author(s)
      可野邦行, 岩間大河, 青木淳賢
    • Organizer
      第46回日本医用マススペクトル学会年会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] LPLAT7/LPGAT1欠損体における網膜変性機構の解析2021

    • Author(s)
      川名 裕己, 柴田 剛明, 岩間 大河, 相良 洋, 佐藤 悠喜飛, 可野 邦行, 河野 望, 青木 淳賢
    • Organizer
      第94回日本生化学会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] ステアリン酸含有リン脂質の培養細胞レベルでの機能解析2021

    • Author(s)
      小澤 雅也, 川名 裕己, 可野 邦行, 河野 望, 青木 淳賢
    • Organizer
      第94回日本生化学会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] ゼブラフィッシュを用いたリン脂質sn-1位ステアリン酸導入酵素LPGAT1の生理機能の解明2020

    • Author(s)
      柴田剛明、川名裕己、青木淳賢
    • Organizer
      第93回生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] ゼブラフィッシュを用いたリン脂質sn-1位ステアリン酸導入酵素LPGAT1の生理機能の解明2020

    • Author(s)
      柴田剛明、川名裕己、青木淳賢
    • Organizer
      日本生化学会東北支部第86回例会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] 230.リゾホスファチジルセリンによるB細胞の活性化抑制機構と活性化B細胞におけるその分泌様式の解析2020

    • Author(s)
      上水 明治、新上 雄司、井上 飛鳥、北村 大介、青木 淳賢
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] リン脂質sn -1位代謝機構による細胞機能の制御2020

    • Author(s)
      川名裕己、小澤雅也、柴田剛明、佐藤悠喜飛、可野邦行、青木淳賢
    • Organizer
      第93回生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] On-tissue derivatization を用いたリン酸基含有脂質のイメージング解析2020

    • Author(s)
      岩間大河、可野邦行、三枝大輔、青木淳賢
    • Organizer
      第93回生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] リン脂質sn-1位脂肪酸導入酵素としてのLPEAT2の生化学的性状解析2020

    • Author(s)
      佐藤悠喜飛、川名裕己、可野邦行、青木淳賢
    • Organizer
      第93回生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K21379
  • [Presentation] リンパ節においてリゾホスファチジルセリンはLPS1を介して適応免疫を活性化する2020

    • Author(s)
      西角駿、深見郁也、近江純平、青木淳賢
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] in vitro B細胞培養系を用いたLysoPSによるB細胞活性化の抑制機構の解析2020

    • Author(s)
      上水 明治、北村 大介、青木 淳賢
    • Organizer
      第93回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] Autocrine lysophosphatidylserine signaling in outer follicles negatively regulates B cell expansion2019

    • Author(s)
      Junken Aoki
    • Organizer
      FASEB Summer Research Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] 腫瘍免疫におけるリゾホスファチジルセリンの機能解析2019

    • Author(s)
      佐藤美希, 近江純平, 深見郁也, 新上雄司, 可野邦行, 青木淳賢
    • Organizer
      第92回日本生化学会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] リゾホスファチジルセリンはオートクライン/パラクライン的に作用し活性化B細胞の凝集塊形成を抑制する2019

    • Author(s)
      上水明治, 新上雄司, 井上飛鳥, 可野邦行, 青木淳賢
    • Organizer
      第92回日本生化学会
    • Data Source
      KAKENHI-PROJECT-19H03366
  • [Presentation] 新規リゾリン脂質メディエーター リゾホスファチジルセリンの免疫抑制機能2018

    • Author(s)
      青木淳賢
    • Organizer
      千里ライフサイエンスセミナーM4
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] PS-PLA1安定発現癌細胞株の作製と腫瘍免疫におけるPS-PLA1の役割2018

    • Author(s)
      佐藤 美希, 深見 郁也, 新上 雄司, 可野 邦行, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 免疫応答の負の制御因子としてのリゾホスファチジルセリン2018

    • Author(s)
      青木淳賢
    • Organizer
      日本生化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] Activation of LPA5 receptor enhances IL-10 production in murine peritoneal macrophage2018

    • Author(s)
      王 嬌, 可野 邦行, 丸山 貴司, 石井 聡, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 初代培養B細胞を用いたリゾホスファチジルセリン産生酵素の探索2018

    • Author(s)
      見 郁也, 佐藤 彗太, 新上 雄司, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 免疫応答の負の制御因子としてのリゾホスファチジルセリン2018

    • Author(s)
      青木淳賢
    • Organizer
      日本生化学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 虚血心臓における DHA 型 LPA の産生機構の解析2018

    • Author(s)
      齋藤 真理恵, 可野 邦行, 川名 裕己, 蔵野 信, 矢冨 裕, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 新規脂質メディエーターリゾホスファチジルセリン ―機能と作動薬開発―2018

    • Author(s)
      青木淳賢、大和田智彦
    • Organizer
      日本薬学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 初代培養リンパ球を用いたリゾホスファチジルセリン産生機構の解析2018

    • Author(s)
      佐藤 慧太, 新上 雄司, 尾谷 優子, 大和田 智彦, 井上 飛鳥, 青木 淳賢
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 新規リゾリン脂質の免疫抑制機能2018

    • Author(s)
      青木淳賢
    • Organizer
      御茶ノ水ソラシティカンファレンスセンター 「ポスト免疫チェックポイントのがん免疫制御2018」
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 新規酸化リン脂質認識GPCRの同定とその炎症抑制機能2018

    • Author(s)
      青木淳賢
    • Organizer
      第16回レドックス・ライフイノベーションシンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 酸化リン脂質の新規薬理作用とその受容体2018

    • Author(s)
      岸 貴之, 井上 飛鳥, 石黒 純, 大村谷 昌樹, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 活性化B細胞におけるLysoPS産生機構の解析2018

    • Author(s)
      辰己 茉菜絵, 新上 雄司, 佐藤 慧太, 深見 郁也, 可野 邦行, 上水 明治, 久下 理, 青木 淳賢
    • Organizer
      日本生化学会
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 急性腹膜炎におけるリゾリン脂質メディエーター LysoPSの変動及び機能解析2017

    • Author(s)
      深見郁也、佐藤慧太、根本祥李、巻出久美子、青木淳賢
    • Organizer
      日本薬学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 新規 LysoPS 受容体の抗体産生における役割2017

    • Author(s)
      新上雄司、巻出久美子、井上飛鳥、青木淳賢
    • Organizer
      日本薬学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 胚中心形成における新規 LysoPS 受容体の役割2017

    • Author(s)
      新上 雄司、佐藤 慧太、深見 郁也、青木 淳賢
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 自己免疫性リンパ球増殖症における新規LysoPS受容体の役割2017

    • Author(s)
      深見 郁也、奥谷 倫世、巻出 久美子、青木 淳賢
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 酸化脂質に応答する霊長類特異的受容体、MRGX4のマウス機能的ホモログの同定2017

    • Author(s)
      岸 貴之、井上 飛鳥、青木 淳賢
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PUBLICLY-17H05494
  • [Presentation] 自閉症スペクトラム障害治療薬の開発に向けたオキシトシン受容体アゴニスト探索2016

    • Author(s)
      鈴木紳吾、堀江謙吾、岸貴之、井上飛鳥、矢田紗織、日出間志寿、青木淳賢、西森克彦
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-15H02442
  • [Presentation] リゾホスファチジルセリン受容体LPS1/GPR34に対する強力且つ選択的アゴニストの開発とその応用2016

    • Author(s)
      上水明治、巻出久美子、中村翔、井上飛鳥、尾谷優子、大和田智彦、青木淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] マスト細胞上のLysoPS受容体探索ツールの開発2016

    • Author(s)
      岸貴之、佐山美沙、巻出久美子、川名裕己、井上飛鳥、尾谷優子、大和田知彦、青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      秋田市にぎわい交流館AU
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-16K15113
  • [Presentation] 腫瘍免疫におけるリゾホスファチジルセリンの役割2016

    • Author(s)
      巻出久美子、新上雄司、井上飛鳥、青木淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] リゾホスファチジルセリン受容体LPS1/GPR34に対する強力且つ選択的アゴニストの開発とその応用2016

    • Author(s)
      上水明治、巻出久美子、中村翔、井上飛鳥、尾谷優子、大和田智彦、青木淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16K15113
  • [Presentation] マスト細胞上のLysoPS受容体探索ツールの開発2016

    • Author(s)
      岸貴之、佐山美沙、巻出久美子、川名裕己、井上飛鳥、尾谷優子、大和田知彦、青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      秋田市にぎわい交流館AU
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 免疫抑制機能を持つ新規リゾリン脂質 メディエーター リゾホスファチジルセリン2016

    • Author(s)
      青木淳賢
    • Organizer
      国立国際医療研究センター研究所セミナー
    • Place of Presentation
      国立国際医療研究センター(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] 新規 LysoPS 受容体の抗体産生における役割2016

    • Author(s)
      新上雄司、巻出久美子、井上飛鳥、青木淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      東北大学川内キャンパス他
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-16H05085
  • [Presentation] リゾリン脂質の GPCR への結合様式解明のための誘導体合成2016

    • Author(s)
      佐山 美紗, ジョン セジン, 中村 翔, 井久保 仁也, 尾谷 優子, 上水 明治, 岸 貴之, 井上 飛鳥, 巻出 久美子, 青木 淳賢, 広川 貴次, 大和田 智彦
    • Organizer
      日本薬学会
    • Place of Presentation
      横浜パシフィコ
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] オキシトシン受容体へのTag付加が与える細胞内局在 シグナル伝達機能への影響の解析2015

    • Author(s)
      鈴木紳吾、岸貴之, 井上飛鳥, 堀江謙吾, 平山貴士, 平岡優一, 日出間志寿, 青木淳賢, 西森克彦
    • Organizer
      第38回日本神経科学会大会
    • Place of Presentation
      兵庫県神戸市・神戸国際会議場、神戸国際展示場
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-15H02442
  • [Presentation] オキシトシン受容体へのタグ付加が与える細胞内局在・機能への影響の検討2015

    • Author(s)
      鈴木紳吾、岸貴之, 井上飛鳥, 堀江謙吾, 平山貴士, 日出間志寿, 青木淳賢, 西森克彦
    • Organizer
      平成27年度 日本農芸化学会 東北支部 第150回大会
    • Place of Presentation
      仙台・東北大学農学部
    • Year and Date
      2015-10-03
    • Data Source
      KAKENHI-PROJECT-15H02442
  • [Presentation] LysoPS受容体のサブタイプ選択的アゴニストの開発2015

    • Author(s)
      上水 明治, 井上 飛鳥, 井久保 仁也, 中村 翔, ジョン セジン, 佐山 美紗, 岸 貴之, 巻出 久美子, 尾谷 優子, 大和田 智彦, 青木 淳賢
    • Organizer
      BMB2015
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] CRISPR/Cas9システムを用いたLysoPS受容体 TKO マウスの作製2015

    • Author(s)
      新上 雄司, 井上 飛鳥, 巻出 久美子, 中島 修, 青木 淳賢
    • Organizer
      BMB2015
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] ホスホリパーゼAの細胞内基質の同定2015

    • Author(s)
      川名裕己、中永景太、青木淳賢
    • Organizer
      BMB2015
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26670021
  • [Presentation] TGFα切断アッセイのハイスループットスクリーニングへの応用2014

    • Author(s)
      上水明治、井上飛鳥、青木 淳賢
    • Organizer
      日本薬学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] 免疫系を制御する新たな脂質メディエーターリゾホスファチジルセリン2014

    • Author(s)
      青木淳賢
    • Organizer
      日本薬学会
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] 免疫系を制御する新たな脂質メディエーターリゾホスファチジルセリン2014

    • Author(s)
      青木 淳賢、巻出 久美子、井上 飛鳥
    • Organizer
      第134回日本薬学会
    • Place of Presentation
      熊本
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] ゼブラフィッシュCa2+動員型プロスタノイド受容体の薬理学的解析2013

    • Author(s)
      岩崎亮、川原敦雄、井上飛鳥、青木淳賢、土屋創健、杉本幸彦
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2013-03-21
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 新しいGPCR活性化測定法TGFα切断アッセイ2013

    • Author(s)
      青木淳賢
    • Organizer
      CBI学会年会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 新しいGPCR活性化測定法TGFα切断アッセイ2013

    • Author(s)
      青木淳賢
    • Organizer
      CBI学会年会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] Lysophosphatidic acid in blood regulates vagal afferent nerves through LPA3 receptor2013

    • Author(s)
      Junken Aoki
    • Organizer
      FASEB SUMMER RESEARCH CONFERENCE
    • Place of Presentation
      Niseko, Hokkaido
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] LysoPSの検出系の確立と生体内におけるLysoPSの検出2013

    • Author(s)
      奥平倫世、井上飛鳥、三枝大輔、富岡佳久、巻出久美子、青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      松島、宮城
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] Lysophosphatidic acid in blood regulates vagal afferent nerves through LPA3 receptor2013

    • Author(s)
      Junken Aoki & Kuniyuki Kano
    • Organizer
      Faseb SRC: Lysophospholipid and Other Related Medaitors-From Bench to Clinic
    • Place of Presentation
      Niseko
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] コンカナバリンA誘導肝炎におけるリゾホスファチジルセリンの機能解析2013

    • Author(s)
      鈴木 健介、奥谷 倫世、井上 飛鳥、巻出 久美子、青木 淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] LysoPS は GPR174 を介して IL-2 産生を抑制する2013

    • Author(s)
      新上 雄司、北村 一、石黒 純、奥谷 倫世、井上 飛鳥、巻出 久美子、井久保 仁也、大和田 智彦、青木 淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] 細胞内型ホスホリパーゼA1の機能解析, Role of intracellular phospholipase A1s in lipid metabolism2013

    • Author(s)
      中永景太、井上飛鳥、青木淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24659025
  • [Presentation] 自己免疫性肝炎モデルにおけるリゾホスファチジルセリンの薬理作用2013

    • Author(s)
      巻出久美子、鈴木健介、井上飛鳥、青木淳賢
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Lipid phophate phosphatase 3 による血管形成制御2013

    • Author(s)
      雪浦弘志、濱弘太郎、中永景太、井上飛鳥、奥平真一、青木淳賢
    • Organizer
      日本薬学会第133年会 シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 酸化リン脂質を認識する&#61511;タンパク質共役型受容体2013

    • Author(s)
      井上飛鳥、石黒純、青木淳賢
    • Organizer
      第55回日本脂質生化学会
    • Place of Presentation
      松島
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] リゾホスファチジルセリンは活性化リンパ球の増殖を抑制する2013

    • Author(s)
      石黒 純、北村 一、首藤 啓明、新上 雄司、井上 飛鳥、巻出 久美子、青木 淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] Autotaxin inhibition attenuated bronchiolitis obliterans in a murine heterotopic tracheal transplant model.2013

    • Author(s)
      Tando Y, Ota C, Yamada M, Takahashi T, Yamaya M, Okudaira S, Aoki J, Kubo H.
    • Organizer
      American thoracic society 2013 international conference
    • Place of Presentation
      アメリカ、フィラデルフィア、フィラデルフィアコンベンションセンター
    • Data Source
      KAKENHI-PROJECT-25670604
  • [Presentation] TGFα切断を用いたGPCRと三量体Gタンパク質の共役活性の評価系の確立2013

    • Author(s)
      井上 飛鳥、青木 淳賢
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] New function of LPA3 receptor that regulates vagal afferent nerves activation2013

    • Author(s)
      可野 邦行、青木淳賢
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Identification and analysis of GPCRs that recognize oxidized phospholipids2013

    • Author(s)
      Asuka Inoue, Jun Ishiguro, Junken Aoki
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 細胞内型ホスホリパーゼA1の機能解析2013

    • Author(s)
      中永 景太、井上 飛鳥、青木 淳賢
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659025
  • [Presentation] リゾホスファチジン酸のマスト細胞における機能解明2012

    • Author(s)
      近藤 朋恵、可野 邦行、奥平 真一、Jerold Chun、青木 淳賢
    • Organizer
      第11回次世代を担う若手ファーマバイオフォーラム2012
    • Place of Presentation
      福岡
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] アカデミック発創薬:東北大学の試み2012

    • Author(s)
      青木淳賢
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] アカデミック発創薬:東北大学の試み2012

    • Author(s)
      青木淳賢
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      札幌(招待講演)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] 血管形成におけるLPAシグナルの解析2012

    • Author(s)
      雪浦弘志、濱弘太郎、奥平真一、中永景太、青木淳賢
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] リゾホスファチジン酸受容体LPA3の活性化は迷走神経刺激の感受性を亢進させる2012

    • Author(s)
      可野邦行、 遠藤智子、 濱弘太郎、 新井洋由、 Jerold Chun、 青木淳賢
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Phospholipid metabolism and Autophagy2012

    • Author(s)
      Keita Nakanaga、 Asuka Inoue、 Junken Aoki
    • Organizer
      LIPID MAPS Annual Meeting 2012
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-05-07
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 血管形成におけるLPAシグナル調節機構の解析2012

    • Author(s)
      雪浦 弘志、濱 弘太郎、奥平 真一、井上 飛鳥、青木淳賢
    • Organizer
      第11回次世代を担う若手ファーマバイオフォーラム2012
    • Place of Presentation
      福岡
    • Year and Date
      2012-09-15
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Lipid phosphate phosphatase 3 (LPP3) による血管形成制御機構の解析2012

    • Author(s)
      雪浦 弘志、濱 弘太郎、奥平 真一、井上 飛鳥、青木淳賢
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] リゾホスファチジン酸受容体LPA3選択的アゴニストは着床痕を劇的に増加させる2012

    • Author(s)
      藍川志津、濱弘太郎、可野邦行、青木淳賢
    • Organizer
      第30回日本受精着床学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2012-08-30
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] LPAはLPA3受容体を介し着床期子宮の血管新生を亢進させる2012

    • Author(s)
      藍川志津、濱弘太郎、可野邦行、青木淳賢
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] TGFα 切断を用いた脂質メディエーター受容体の検出法の開発2012

    • Author(s)
      井上 飛鳥、石黒 純、巻出 久美子、青木 淳賢
    • Organizer
      第54回日本脂質生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 毛髪形成メカニズムから派生したGタンパク質共役型受容体(GPCR)の新規検出系の開発とその応用2012

    • Author(s)
      井上 飛鳥、石黒 純、巻出 久美子、青木 淳賢
    • Organizer
      第85回日本生化学会大会 シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] セリンリゾリン脂質を認識する新規GPCRとその機能2012

    • Author(s)
      青木淳賢、 井上飛鳥、 巻出久美子
    • Organizer
      第85回日本生化学会大会 シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Development of a versatile GPCR assay and its application for ligand identification of orphan GPCRs2012

    • Author(s)
      Asuka Inoue、 Jun Ishiguro、 Kumiko Makide and Junken Aoki
    • Organizer
      LIPID MAPS Annual Meeting 2012
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2012-05-07
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] ゼブラフィッシュ プロスタノイド受容体のクローニングと性状解析2011

    • Author(s)
      告恭史郎, 岩崎亮, 川原敦雄, 井上飛鳥, 青木淳賢, 杉本幸彦
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] リゾホスファチジルセリンの細胞接着抑制作用2011

    • Author(s)
      北村一、青木淳賢
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Autotaxin regulates vascular development via multiple LPA receptors in zebrafish2011

    • Author(s)
      Junken Aoki
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-15
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Presentation] 生理活性リゾリン脂質の定量系の開発と産生機構の解析2011

    • Author(s)
      井上飛鳥、青木淳賢
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Autotaxin regulates vascular development via multiple LPA receptors in zebrafish2011

    • Author(s)
      Junken Aoki
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-15
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] New aspects of autotaxin : structure and function2011

    • Author(s)
      Junken Aoki, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy(招待講演)
    • Year and Date
      2011-08-14
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] New aspects of autotaxin : structure and function2011

    • Author(s)
      Junken Aoki, 他
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy(招待講演)
    • Year and Date
      2011-08-14
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] TGF-alpha ectodomain shedding underlies LPA-induced hair formation2011

    • Author(s)
      Asuka Inoue, Junken Aoki
    • Organizer
      2011 FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy
    • Year and Date
      2011-08-14
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 肺線維症におけるオートタキシンの機能解析2011

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      日本薬学会第130年会
    • Place of Presentation
      岡山
    • Year and Date
      2011-03-30
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] ゼブラフィッシュ体節間血管形成におけるリゾホスファチジン酸シグナルの作用機序2011

    • Author(s)
      濱弘太郎、青木淳賢
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Autaxin regulates vascular development via multiple LPA receptors in zebrafish2011

    • Author(s)
      Aoki J
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Lucca, Italy(招待講演)
    • Year and Date
      2011-08-15
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Immunosuppressive roles of lysophosphatidylserine in mice2011

    • Author(s)
      Kumiko Makide, Junken Aoki
    • Organizer
      第40回日本免疫学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2011-11-27
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] ワークショップ「脂質マシナリー」2010

    • Author(s)
      村上誠、青木淳賢, オーガナイザー
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会ワークショップ
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 血中におけるリゾホスファチジルコリン産生機構の解明2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      第129年会日本薬学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] リゾホスファチジン酸産生酵素オートタキシンの血管形成過程における役割2010

    • Author(s)
      中永景太, 青木淳賢
    • Organizer
      第15回小型魚類研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-09-12
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 血中におけるリゾホスファチジルコリン産生機構の解明2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      次世代を担う若手ファーマ・バイオフォーラム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      The 5th Takeda Science Foundation Symposium on PharmaSciences
    • Place of Presentation
      東京
    • Year and Date
      2010-05-26
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] ゼブラフィッシュを用いたオートタキシンの血管形成メカニズムの解析2010

    • Author(s)
      中永景太, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 血中におけるリゾホスファチジルコリン産生機構の解明2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      日本生化学会東北支部第75回例会
    • Place of Presentation
      仙台
    • Year and Date
      2010-05-09
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Baculovirusを用いたオートタキシンの大量発現系の確立2010

    • Author(s)
      菅野究, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      4th International Conference on Phospholipase A2 and Lipid Mediators (PLM2009)
    • Place of Presentation
      東京
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      Keystone Symposia Bioactive Lipids : Biochemistry and Diseases (D2)
    • Place of Presentation
      Kyoto, Westin Miyako Kyoto
    • Year and Date
      2010-06-07
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] 血中におけるリゾホスファチジルコリン産生機構の解明2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      第6回東北大学バイオサイエンスシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 肺線維症におけるリゾホスファチジン酸産生酵素オートタキシンの機能解析2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      第51回日本脂質生化学会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis, Bioactive Lipids in Cancer, Infalammation and Related Disease2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      11th International Conference
    • Place of Presentation
      メキシコカンクン
    • Year and Date
      2010-10-25
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      International Vascular Biology Meeting 2010
    • Place of Presentation
      Los Angels, CA, USA
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      Junken Aoki
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-06-08
    • Data Source
      KAKENHI-PROJECT-22659013
  • [Presentation] 肺線維症におけるリゾホスファチジン酸産生酵素オートタキシンの機能解析2010

    • Author(s)
      青木淳賢
    • Organizer
      第6回東京呼吸器リサーチフォーラム
    • Place of Presentation
      東京
    • Year and Date
      2010-11-07
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 血中におけるリゾホスファチジルコリン産生機構の解明2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Pathways for LPA production and their path-physiological roles2010

    • Author(s)
      青木淳賢
    • Organizer
      FASEB SummerResearchConference"Lysophospholipid Mediators in Health and Disease"
    • Place of Presentation
      アメリカアリゾナ
    • Year and Date
      2010-06-28
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Roles of Autotaxin in Pulmonary Fibrosis FASEB Summer Research Conference2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      Lysophospholipid Mediators in Health and Disease
    • Place of Presentation
      アメリカアリゾナ
    • Year and Date
      2010-06-28
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Physiological roles of Autotaxin during late pregnancy2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      4th International Conference on Phospholipase A2 and Lipid Mediators (PLM2009)
    • Place of Presentation
      東京
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] オートタキシントランスジェニックマウスの解析2010

    • Author(s)
      雪浦弘志, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] トリプシンによって切断されるAutotaxinの性状解析2010

    • Author(s)
      小川貴子, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      International Vascular Biology Meeting 2010
    • Place of Presentation
      Los Angels, CA, USA
    • Year and Date
      2010-06-20
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] ATX-LPAシグナルのS1Pシグナル抑制機構2010

    • Author(s)
      中永景太, 青木淳賢
    • Organizer
      次世代を担う若手ファーマ・バイオフォーラム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      青木淳賢
    • Organizer
      Keystone Symposia Bioactive Lipids : Biochemistry and Diseases (D2)
    • Place of Presentation
      Kyoto, Westin Miyako Kyoto
    • Year and Date
      2010-06-07
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] コンディショナルノックアウトマウスを用いたオートタキシンの機能解析2010

    • Author(s)
      有馬直明, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] トリプシンによって切断されるAutotaxinの性状解析2010

    • Author(s)
      小川貴子, 青木淳賢
    • Organizer
      第48回日本薬学会東北支部大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-10-18
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 肺線維症におけるリゾホスファチジン酸産生酵素オートタキシンの機能解析2010

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      第82回日本生化学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-10-23
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Autotaxin and LPA Signaling in Cardiovascular Development2010

    • Author(s)
      Junken Aoki
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Kyoto, Japa
    • Year and Date
      2010-06-08
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] Physiological roles of Autotaxin during late pregnancy2010

    • Author(s)
      小野めぐみ, 青木淳賢
    • Organizer
      The 5th Takeda Science Foundation Symposium on PharmaSciences
    • Place of Presentation
      東京
    • Year and Date
      2010-05-26
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Two pathways for LPA production and their path-physiological roles2010

    • Author(s)
      青木淳賢
    • Organizer
      The 5th Takeda Science Foundation Symposium on PharmaSciences
    • Place of Presentation
      東京
    • Year and Date
      2010-05-26
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 創傷治癒におけるリゾホスファチジン酸産生酵素autotaxinの機能解析2009

    • Author(s)
      奥平真一, 青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 生理活性リゾリン脂質-新しいドラッグターゲット-2009

    • Author(s)
      青木淳賢
    • Organizer
      東北大学バイオシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2009-06-06
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] メディエーターとしての生体膜脂質の機能-リゾリン脂質メディエーターの生理・病態機能-2009

    • Author(s)
      青木淳賢
    • Organizer
      生体パーオキシド研究会
    • Place of Presentation
      仙台
    • Year and Date
      2009-08-30
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] リゾホスファチジン酸産生酵素オートタキシンの初期炎症過程における機能2009

    • Author(s)
      青木淳賢
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Pthways for LPA production and their patho-physiological roles2009

    • Author(s)
      Junken Aoki
    • Organizer
      2009 FASEB Summer Research Conference
    • Place of Presentation
      Arizona, USA
    • Year and Date
      2009-06-29
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] 肝障害時における血中autotaxin発現変動の解析2009

    • Author(s)
      小川貴子, 青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] VE-カドヘリンの接着抑制に関わる内皮細胞上のLPA受容体の解析2009

    • Author(s)
      中永景太, 青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Pathways for LPA production and their path-physiological roles2009

    • Author(s)
      青木淳賢
    • Organizer
      FASEB Summer Research Conference "Lysophospholipid Mediators in Health and Disease"
    • Place of Presentation
      アメリカ アリゾナ
    • Year and Date
      2009-06-28
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Role of autotaxin in lysophosphatidic acid-induced hypertension in murine plasma2009

    • Author(s)
      可野邦行, 青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] コンディショナルノックアウトマウスを用いたリゾホスファチジン酸産生酵素オートタキシンの機能解析2009

    • Author(s)
      大上満, 青木淳賢
    • Organizer
      ファーマ・バイオフォーラム2008
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 細がん細胞の運動・増殖性促進因子オートタキシンは血管新生を促進する2009

    • Author(s)
      青木淳賢
    • Organizer
      日本癌学会シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2009-12-30
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] 生理活性リゾリン脂質の生体内機能-リゾリン脂質メディエーターの生理・病態機能-2009

    • Author(s)
      青木淳賢
    • Organizer
      第30回東北薬学セミナー
    • Place of Presentation
      仙台
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] Pathways for LPA production and their path-physiological roles2009

    • Author(s)
      青木淳賢
    • Organizer
      FASEB Summer Research Conference "Lysophospholipid Mediators in Health and Disease"
    • Place of Presentation
      アメリカアリゾナ
    • Year and Date
      2009-06-28
    • Data Source
      KAKENHI-PROJECT-21390015
  • [Presentation] リゾホスファチジン酸受容体LPA3の降圧メカニズムの解析2008

    • Author(s)
      可野邦行、遠藤智子、池下和樹、長谷川英之、金井浩、Jerold Chun、青木淳賢
    • Organizer
      ファーマ・バイオフォーラム2008
    • Place of Presentation
      渋谷、日本薬学会長井記念ホール
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] PS-PLA1とmPA-PLA1aの基質特異性におけるループ構造の関与2008

    • Author(s)
      有馬直明、井上飛鳥、巻出久美子、青木淳賢
    • Organizer
      第47回日本薬学会東北支部大会
    • Place of Presentation
      岩手, 岩手医科大学薬学部
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] リゾホスファチジン酸受容体LPA3の新規生理機能2008

    • Author(s)
      青木淳賢
    • Organizer
      第5回GPCR研究会シンポジウム
    • Place of Presentation
      東京、日本科学未来館
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] 生理活性リゾリン脂質の生体内機能リゾリン脂質メディエーターの生理・病態機能2008

    • Author(s)
      青木淳賢
    • Organizer
      第30回東北薬学セミナー(特別講演)
    • Place of Presentation
      仙台、江陽グランドホテル
    • Year and Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] ホスファチジン酸特異的ホスホリパーゼAlの体毛形成への関与2008

    • Author(s)
      井上飛鳥、有馬直明、新井洋由、青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      徳島県徳島市徳島県郷土文化会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] VE-カドヘリンの接着抑制に関わる内皮細胞上のLPA受容体の解析2008

    • Author(s)
      中永景太、田中将之、望月直樹、金井求、柴崎正勝、新井洋由、青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸、神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] 初期炎症反応に生理活性脂質リゾホスファチジン酸の役割2008

    • Author(s)
      青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      徳島県徳島市徳島県郷土文化会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] コンディショナルノックアウトマウスを用いたリゾホスファチジン酸産生酵素オートタキシンの機能解析2008

    • Author(s)
      大上満、奥平真一、Wouter Moolenaar、新井洋由、青木淳賢
    • Organizer
      ファーマ・バイオフォーラム2008
    • Place of Presentation
      東京都、渋谷、日本薬学会長井記念ホール
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] リゾホスファチジン酸産生酵素オートタキシンの初期炎症過程における機能2008

    • Author(s)
      青木淳賢、奥平真一、新井洋由
    • Organizer
      第50回日本脂質生化学会
    • Place of Presentation
      徳島、徳島県郷土文化会館
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] コンディショナルノックアウトマウスを用いたリゾホスファチジン酸産生酵素オートタキシンの機能解析2008

    • Author(s)
      大上満、奥平真一、Wouter Moolenaar、新井洋由、青木淳賢
    • Organizer
      ファーマ・バイオフォーラム2008
    • Place of Presentation
      東京都、渋谷、日本薬学会長井記念ホール
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] オーファンGPCR, P2Y10のリガンド探索と機能解析2008

    • Author(s)
      北村一、巻出久美子、秋山るみ、佐藤侑介、青木淳賢
    • Organizer
      ファーマ・バイオフオーラム2008
    • Place of Presentation
      東京、渋谷、日本薬学会長井記念ホール
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Presentation] 生理活性リゾリン脂質-新しいドラッグターゲット2008

    • Author(s)
      青木淳賢
    • Organizer
      東北大学バイオシンポジウム
    • Place of Presentation
      東京、サピアタワー
    • Year and Date
      2008-06-06
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] リゾボスファチジルセリン受容体GPR34の解析2008

    • Author(s)
      巻出久美子、佐藤侑介、北村一、秋山るみ、青木淳賢
    • Organizer
      BMB2008
    • Place of Presentation
      兵庫県、神戸、国際会議場
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Presentation] P2Y10受容体のリガンド探索と機能解析2008

    • Author(s)
      北村一、巻出久美子、秋山るみ、佐藤侑介、青木淳賢
    • Organizer
      BMB2008
    • Place of Presentation
      兵庫県、神戸、国際会議場
    • Data Source
      KAKENHI-PROJECT-19659014
  • [Presentation] メディエーターとしての生体膜脂質の機能-リゾリン脂質メディエーターの生理・病態機能2008

    • Author(s)
      青木淳賢
    • Organizer
      生体パーオキシド研究会特別講演
    • Place of Presentation
      仙台、勝山館
    • Year and Date
      2008-08-30
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] 初期炎症反応に生理活性脂質リゾホスファチジン酸の役割2008

    • Author(s)
      青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      徳島県徳島市徳島県郷土文化会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] ホスファチジン酸特異的ホスホリパーゼA1の体毛形成への関与2008

    • Author(s)
      井上飛鳥、有馬直明、新井洋由、青木淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      徳島県徳島市徳島県郷土文化会館
    • Year and Date
      2008-06-05
    • Data Source
      KAKENHI-PROJECT-20013005
  • [Presentation] リゾホスファチジルセリン受容体GPR34の解析2008

    • Author(s)
      巻出久美子、佐藤侑介、北村一、秋山るみ、青木淳賢
    • Organizer
      BMB2008第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸、神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid2007

    • Author(s)
      Junken Aoki
    • Organizer
      The 3rd International conference on phospholipases A2 and lipid mediators
    • Place of Presentation
      Sorrento, Italy
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] リゾホスファチジン酸の病態・生理機能2007

    • Author(s)
      青木淳賢
    • Organizer
      BMB2007
    • Place of Presentation
      横浜, パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] リゾホスファチジルセリンによるマスト細胞活性化機構の解析2007

    • Author(s)
      巻出久美子、新井洋由、青木淳賢
    • Organizer
      BMB2007
    • Place of Presentation
      横浜, パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] 生理活性脂質研究の新しい流れ2007

    • Author(s)
      青木淳賢
    • Organizer
      生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19390018
  • [Presentation] LPA3を介する迷走神経機能の解明

    • Author(s)
      可野 邦行、青木 淳賢
    • Organizer
      日本脂質生化学会
    • Place of Presentation
      大阪
    • Year and Date
      2014-06-06 – 2014-06-07
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] 免疫系を制御する新たな脂質メディエーターリゾホスファチシジルセリン

    • Author(s)
      青木淳賢
    • Organizer
      第35回再生・炎症学会
    • Place of Presentation
      沖縄
    • Year and Date
      2014-07-01 – 2014-07-04
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Novel GPCRs for lysophosphatidylserine; their structure and function

    • Author(s)
      Junken Aoki
    • Organizer
      6th International Conference on Phospholipase A2 and Lipid Mediators
    • Place of Presentation
      Tokyo
    • Year and Date
      2015-02-10 – 2015-02-12
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Novel GPCRs for lysophosphatidylserine; their structure and function

    • Author(s)
      Junken Aoki
    • Organizer
      PLM2015
    • Place of Presentation
      東京
    • Year and Date
      2015-02-10 – 2015-02-12
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] Novel Receptors for lysophosphatidylserine; their structure and function

    • Author(s)
      Junken Aoki
    • Organizer
      FEPS2014
    • Place of Presentation
      Budapest
    • Year and Date
      2015-08-16 – 2015-08-29
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] LPP3 maintains vascular stability by negatively regulating LPA signal

    • Author(s)
      Junken Aoki, Hiroshi Yukiura, Kuniyuki Kano, Asuka Inoue
    • Organizer
      18th International Vascular Biology Meeting
    • Place of Presentation
      Kyoto
    • Year and Date
      2015-04-14 – 2015-04-17
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] LPP3 maintains vascular stability by negatively regulating LPA signal

    • Author(s)
      Junken Aoki, Hiroshi Yukiura, Kuniyuki Kano, Asuka Inoue
    • Organizer
      18th International Vascular Biology Meeting
    • Place of Presentation
      京都
    • Year and Date
      2014-04-14 – 2014-04-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] リゾリン脂質 - 基礎から創薬まで -

    • Author(s)
      青木淳賢
    • Organizer
      メディシナリーケミストリーシンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2014-11-26 – 2014-11-28
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] Novel Receptors for lysophosphatidylserine; their structure and function

    • Author(s)
      Junken Aoki
    • Organizer
      FEPS2014 (Federation of European Physiological Societies 2014)
    • Place of Presentation
      Budapest (ハンガリー)
    • Year and Date
      2014-08-26 – 2014-08-29
    • Invited
    • Data Source
      KAKENHI-PLANNED-22116004
  • [Presentation] Novel Receptors for lysophosphatidylserine; their structure and function

    • Author(s)
      Junken Aoki
    • Organizer
      FEPS2014 (Federation of European Physiological Societies 2014)
    • Place of Presentation
      Budapest (ハンガリー)
    • Year and Date
      2014-08-26 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-25293010
  • [Presentation] A novel path-physiological role of bioactive lysophospholipid, lysophosphatidic acid

    • Author(s)
      青木 淳賢、可野 邦行
    • Organizer
      第88回日本薬理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-03-18 – 2015-03-20
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22116001
  • [Presentation] 免疫系を制御する新たな脂質メディエーターリゾホスファチシジルセリン

    • Author(s)
      青木淳賢
    • Organizer
      第35回再生・炎症学会、
    • Place of Presentation
      沖縄
    • Year and Date
      2014-07-02 – 2014-07-04
    • Data Source
      KAKENHI-PROJECT-25293010
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  • 1.  ARAI Hiroyuki (40167987)
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