Murata Shigeo 村田茂穂

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MURATA Shigeo 村田茂穂

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Researcher Number	20344070
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院薬学系研究科(薬学部), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 東京大学, 大学院薬学系研究科(薬学部), 教授 2019: 東京大学, 薬学研究科(研究院), 教授 2014 – 2016: 東京大学, 大学院薬学研究科, 教授 2011 – 2015: 東京大学, 薬学研究科(研究院), 教授 2013: 東京大学, 大学院薬学系研究科, 教授 … More 2007 – 2013: 東京大学, 大学院・薬学系研究科, 教授 2008: 東京都医学研究機構, 研究員 2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 主任研究員 2007: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 研究員 2002 – 2006: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 2004: The Tokyo Metropolitan, Institute of Medical Science, Researcher, 東京都臨床医学綜合研究所, 研究員 2003: 科学技術振興機構, さきがけプログラム, 研究員 2002: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Functional biochemistry / Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 43030:Functional biochemistry-related / Medium-sized Section 48:Biomedical structure and function and related fields / Complex systems / Biological pharmacy / Biological Sciences / Neurochemistry/Neuropharmacology … More Except Principal Investigator … More Biological Sciences / Biological Sciences / Complex systems / Metabolomics / Biological pharmacy Less
Keywords	Principal Investigator プロテアソーム / ユビキチン / タンパク質分解 / 神経変性疾患 / シャペロン / 分子集合 / タンパク質品質管理 / 質量分析 / タウ / 神経変性 … More / ペプチド / ユビキチンリガーゼ / タンパク質寿命 / アグリソーム / ケミカルバイオロジー / オートファジー / 変性タンパク質 / SOD1 / タンパク質恒常性 / siRNAスクリーニング / T細胞 / 胸腺 / ストレス / 品質管理 / 酵母遺伝学 / 限定分解 / 液滴 / プロテオーム / 個体老化 / 細胞老化 / 若手育成 / 標的タンパク質分解 / 栄養 / mTOR / 細胞内局在 / リソソーム / ゲノムワイドスクリーニング / ESCRT-I / ミクログリア / ミクロオートファジー / ESCRT複合体 / 凝集性タンパク質 / アミロイド / ESCRT / 異常タンパク質 / 凝集 / プロテオスターシス / ダイニン / 核外移行 / 構造異常タンパク質 / 化合物スクリーニング / ステープルペプチド / キメラ化合物 / 細胞内分解 / ケモテクノロジー / オルガネラ分解 / 標的タンパク質分解誘導 / ミトファジー / PROTAC / 化合物 / 創薬 / スクリーニング / 低分子化合物 / ミスフォールドタンパク質 / 筋萎縮性側索硬化症 / アルツハイマー病 / 病態 / 細胞内動態 / 転写制御 / 病態生理 / Nrf1 / 転写 / がん / 酵素 / 細胞内タンパク質分解 / 正の選択 / 免疫 / ノックアウトマウス / 小脳失調 / 分子シャペロン / 骨分化 / TGFβ / CDKインヒビター / 細胞周期 … More Except Principal Investigator ユビキチン / プロテアソーム / タンパク質分解 / オートファジー / proteasome / 脳神経疾患 / 蛋白質 / 免疫学 / ユビキチンリガーゼ / シグナル伝達 / ubiquitin / プロテオーム / 酵素 / バイオテクノロジー / 品質管理 / 神経変性疾患 / 分子集合 / 蛋白質分解 / ノックアウトマウス / シャペロン / ステープルペプチド / タンパク質化学合成 / 標的タンパク質分解誘導剤 / 翻訳後修飾 / ケミカルバイオロジー / neurodegenerative diseases / protein / stress / signal transduction / enzyme / ユビキチン様蛋白質 / NEDD8 / SCF / PA28 / 抗原プロセシング / ストレス / 液-液相分離 / メンブレンレスオルガネラ / 液滴 / RAD23B / プロテアソーム顆粒 / バノオテクノロジー / マイトファジー / type 2 diabetes / obesity / ER stress / liver / insulin resistance / 脂質代謝 / 糖代謝 / 蛋白代謝 / 糖質代謝異常 / エネルギー / 小胞体ストレス / 肥満 / 肝臓 / インスリン抵抗性 / autophagy / T細胞 / 胸腺 / ATP / 胸腺特異的プロテアソーム / ATP依存性プロテアーゼ / ガン / 分子多様性 / 小脳失調 / 分子シャペロン / タンパク質品質管理 / Ufm1 / ユビキチン様分子 / CHIP Less

Shin-biology regulated by protein lifetimeArea Organizer
- Area Organizer
  
  村田茂穂
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
Shin-biology regulated by protein lifetimePrincipal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
細胞・臓器老化におけるタンパク質寿命動態Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
プロテアソーム分解により機能を獲得するタンパク質およびペプチドの網羅的探索Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
凝集性タンパク質の新しい動態制御機構解明と病態連関の解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
構造異常タンパク質の細胞内動態制御機構とその病態生理的意義の解明Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  The University of Tokyo
New frontier for ubiquitin biology driven by chemo-technologies
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Regulation of protein degradation by chemo-technologyPrincipal Investigator
- Principal Investigator
  
  Murata Shigeo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Regulatory mechanism of intracellular dynamics of conformationally aberrant proteins and its pathophysiological significancePrincipal Investigator
- Principal Investigator
  
  Murata Shigeo
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  The University of Tokyo
ミスフォールドタンパク質の核外排出分子機構の解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Screening for proteasome-activating compounds that could cure neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  Murata Shigeo
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
The Proteasome: Mechanistic Actions and In-depth Physiopathological Analyses
- Principal Investigator
  
  TANAKA Keiji
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Dynamics and function of the proteasomePrincipal Investigator
- Principal Investigator
  
  Murata Shigeo
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Significance of proteasome dysfunction in the development of obesity-mediated hepatic insulin resistance
- Principal Investigator
  
  TAKAMURA Toshinari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Roles of degradation products generated by the proteasomePrincipal Investigator
- Principal Investigator
  
  MURATA Shigeo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Studies on the assembly of the proteasome
- Principal Investigator
  
  KANEKO Takeumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
In-depth Analysis of Proteasome-Mediated Regulatory Proteolysis
- Principal Investigator
  
  TANAKA Keiji
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
正の選択を制御するペプチドの解析
- Principal Investigator
  
  YASHIRODA Hideki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
プロテアソームの形成と発現制御機構の解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Regulation of acquired immunity by thymus-specific proteasomesPrincipal Investigator
- Principal Investigator
  
  MURATA Shigeo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
  Tokyo Metropolitan Organization for Medical Research
Analyses of Molecular Assembly and Diversity of Proteasomes
- Principal Investigator
  
  TANAKA Keiji
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
ニューロンにおける品質管理の遺伝学的解析
- Principal Investigator
  
  小松雅明
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
プロテアソームの分子集合に関与する因子の同定と解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
タンパク質品質管理を担うシャペロン依存型ユビキチンリガーゼCHIPの遺伝学的解析
- Principal Investigator
  
  KOMATSU Masaaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
  Tokyo Metropolitan Organization for Medical Research
p57^<kip2>のユビキチンリガーゼ(E3)の同定Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
タンパク質品質管理を担うシャペロン依存型ユビキチンリガーゼCHIPの遺伝学的解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
タンパク質品質管理を担うシャペロン依存型ユビキチンリガーゼの遺伝学的解析Principal Investigator
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Studies on proteolysis mediated by the proteasomes and ubiquitin
- Principal Investigator
  
  TANAKA Keiji
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Organization for Medical Research

[Book] Curr.Opini.Immunol2012
- Author(s)
  Takahama, Y., Takada, K., Murata, S., Tanaka, K.
- Total Pages
  7
- Publisher
  Elsevier Ltd.
- Data Source
  KAKENHI-PROJECT-21000012
[Book] タンパク質分解系による生体制御2011
- Author(s)
  村田茂穂、反町洋之　編集
- Total Pages
  242
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23657083
[Book] Ubiquity and diversity of the proteasome system. In " Protein Degradation"(Eds. By Mayer, R. J., Ciechanover, A., and Rechsteiner, M.)2006
- Author(s)
  Tanaka, K., Yashiroda, H., Murata, S.
- Publisher
  Wiley-VCH Verlag GmbH, Weinheim, Germany
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Book] Ubiquity and diversity of the proteasome system. In " Protein Degradation" (Eds. By Mayer, R. J., Ciechanover, A., and Rechsteiner, M.)2006
- Author(s)
  Tanaka, K., Yashiroda, H., Murata, S.
- Publisher
  Wiley-VCH Verlag GmbH, Weinheim, Germany
- Data Source
  KAKENHI-PROJECT-17002019
[Book] Methods in Enzymology : Large- and small-scale purification of mammalian 26S proteasomes.2005
- Author(s)
  Hirano, Y., Murata, S., Tanaka, K.
- Publisher
  Academic Press, New York(in press)
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Changes in brain proteasome dynamics associated with aging2024
- Author(s)
  Nago Nodoka、Murata Shigeo、Tanaka Keiji、Tanahashi Nobuyuki
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 5 Pages: 1-8
- DOI
  10.1111/gtc.13113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17650, KAKENHI-PLANNED-23H04918, KAKENHI-PROJECT-22H00419
[Journal Article] Relationships between protein degradation, cellular senescence, and organismal aging2024
- Author(s)
  Hamazaki Jun、Murata Shigeo
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 0 Issue: 5 Pages: 0-0
- DOI
  10.1093/jb/mvae016
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23H04918
[Journal Article] Senescent cells form nuclear foci that contain the 26S proteasome2023
- Author(s)
  Iriki Tomohiro、Iio Hiroaki、Yasuda Shu、Masuta Shun、Kato Masakazu、Kosako Hidetaka、Hirayama Shoshiro、Endo Akinori、Ohtake Fumiaki、Kamiya Mako、Urano Yasuteru、Saeki Yasushi、Hamazaki Jun、Murata Shigeo
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112880-112880
- DOI
  10.1016/j.celrep.2023.112880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18107, KAKENHI-PROJECT-22K06611, KAKENHI-WRAPUP-23H05424, KAKENHI-ORGANIZER-23H04917, KAKENHI-PLANNED-23H04918, KAKENHI-PLANNED-23H04921, KAKENHI-PROJECT-23H05479, KAKENHI-PROJECT-22H00402
[Journal Article] Caspase cleaves<i>Drosophila</i><scp>BubR1</scp>to modulate spindle assembly checkpoint function and lifespan of the organism2023
- Author(s)
  Shinoda Natsuki、Horikoshi Misuzu、Taira Yusuke、Muramoto Masaya、Hirayama Shoshiro、Murata Shigeo、Miura Masayuki
- Journal Title
  
  The FEBS Journal
  
  Volume: 290 Issue: 17 Pages: 4200-4223
- DOI
  10.1111/febs.16811
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18107, KAKENHI-PROJECT-23K05747, KAKENHI-PUBLICLY-22H05586, KAKENHI-PLANNED-23H04918, KAKENHI-PROJECT-21H04774, KAKENHI-PROJECT-22H00402
[Journal Article] Acute irradiation causes a long-term disturbance in the heterogeneity and gene expression profile of medullary thymic epithelial cells2023
- Author(s)
  Horie Kenta、Namiki Kano、Kinoshita Kyouhei、Miyauchi Maki、Ishikawa Tatsuya、Hayama Mio、Maruyama Yuya、Hagiwara Naho、Miyao Takahisa、Murata Shigeo、Kobayashi Tetsuya J.、Akiyama Nobuko、Akiyama Taishin
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 1186154-1186154
- DOI
  10.3389/fimmu.2023.1186154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19391, KAKENHI-PROJECT-23K06385, KAKENHI-PROJECT-20K07332, KAKENHI-PLANNED-23H04918
[Journal Article] The effect of nutrient deprivation on proteasome activity in 4-week-old mice and 24-week-old mice2022
- Author(s)
  Nobuyuki Tanahashi, Moeko Komiyama, Mina Tanaka, Yuta Yokobori Shigeo Murata, and Keiji Tanaka
- Journal Title
  
  Journal of Nutritional Biochemistry
  
  Volume: 0 Pages: 0-0
- DOI
  10.1016/j.jnutbio.2022.108993
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11658, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-22H00402, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500
[Journal Article] The Molecular Mechanisms Governing the Assembly of the Immuno- and Thymoproteasomes in the Presence of Constitutive Proteasomes2022
- Author(s)
  Watanabe Ayaka、Yashiroda Hideki、Ishihara Satoshi、Lo Megan、Murata Shigeo
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 9 Pages: 1580-1580
- DOI
  10.3390/cells11091580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00402, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500
[Journal Article] The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation2021
- Author(s)
  Takehara Yuka、Yashiroda Hideki、Matsuo Yoshitaka、Zhao Xian、Kamigaki Akane、Matsuzaki Tetsuo、Kosako Hidetaka、Inada Toshifumi、Murata Shigeo
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 3 Pages: 102145-102145
- DOI
  10.1016/j.isci.2021.102145
- NAID
  120007182109
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06481, KAKENHI-PROJECT-20K06628, KAKENHI-PUBLICLY-19H04966, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022
[Journal Article] Heterozygous missense variant of the proteasome subunit β-type 9 causes neonatal-onset autoinflammation and immunodeficiency2021
- Author(s)
  Kanazawa N, Hemmi H, Kinjo N, Ohnishi H, Hamazaki J, M.H, K.A, M.T, H.S, K.N, K.S, H.Y, I.K, N.R, T.M, Y.Y, T.S, O.T, O.T, K.T, S.I, F.Y, W.N, I.Y, K.K, O.S, T.T, N.K, M.S, Y.K, Kaisho T
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 0-0
- DOI
  10.1038/s41467-021-27085-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K07628, KAKENHI-PROJECT-19K08299, KAKENHI-PROJECT-20K16289, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-19H03620, KAKENHI-PROJECT-20H03505, KAKENHI-PROJECT-20H03591, KAKENHI-PROJECT-21J22615, KAKENHI-PROJECT-19K08754, KAKENHI-PROJECT-19K08798, KAKENHI-PROJECT-19K09993, KAKENHI-PROJECT-20K08158, KAKENHI-PROJECT-20K08718, KAKENHI-PROJECT-21K06956, KAKENHI-PROJECT-21K07770, KAKENHI-PROJECT-21K07800, KAKENHI-PROJECT-21K19384, KAKENHI-PROJECT-20K17405
[Journal Article] Gluing Proteins for Targeted Degradation2021
- Author(s)
  Naito Mikihiko、Murata Shigeo
- Journal Title
  
  Cancer Cell
  
  Volume: 39 Issue: 1 Pages: 19-21
- DOI
  10.1016/j.ccell.2020.12.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05502, KAKENHI-ORGANIZER-18H05497
[Journal Article] Enhanced O-GlcNAcylation Mediates Cytoprotection under Proteasome Impairment by Promoting Proteasome Turnover in Cancer Cells2020
- Author(s)
  Hashimoto E, Okuno S, Hirayama S, Arata Y, Goto T, Kosako H, Hamazaki J, Murata S.
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 7 Pages: 101299-101299
- DOI
  10.1016/j.isci.2020.101299
- NAID
  120007127449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-ORGANIZER-18H05497
[Journal Article] NRF3-POMP-20S proteasome assembly axis promotes cancer development via ubiquitin-independent proteolysis of p53 and Rb.2020
- Author(s)
  Waku T, Nakamura N, Koji M, Watanabe H, Katoh H, Tatsumi C, Tamura N, Hatanaka A, Hirose S, Katayama H, Tani M, Kubo Y, Hamazaki J, Hamakubo T, Watanabe A, Murata S, Kobayashi A
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: - Issue: 10 Pages: 1-1
- DOI
  10.1128/mcb.00597-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-20H04135, KAKENHI-ORGANIZER-18H05497
[Journal Article] Stress- and ubiquitylation-dependent phase separation of the proteasome2020
- Author(s)
  Yasuda Sayaka、Tsuchiya Hikaru、Kaiho Ai、Guo Qiang、Ikeuchi Ken、Endo Akinori、Arai Naoko、Ohtake Fumiaki、Murata Shigeo、Inada Toshifumi、Baumeister Wolfgang、Fernandez-Busnadiego Ruben、Tanaka Keiji、Saeki Yasushi
- Journal Title
  
  Nature
  
  Volume: 578 Issue: 7794 Pages: 296-300
- DOI
  10.1038/s41586-020-1982-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05500, KAKENHI-PUBLICLY-19H05281, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-18K14913, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-19H00997
[Journal Article] ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond2020
- Author(s)
  Hamazaki J, Murata S.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 10 Pages: 3683-3683
- DOI
  10.3390/ijms21103683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-18H05500
[Journal Article] Recognition and degradation of ubiquitinated proteins by the 26S proteasome2020
- Author(s)
  濱崎　純、村田　茂穂
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 48-56
- DOI
  10.14952/SEIKAGAKU.2020.920048
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-ORGANIZER-18H05497
[Journal Article] タンパク質分解装置プロテアソームと創薬2020
- Author(s)
  村田茂穂、池浦隆真
- Journal Title
  
  Farumashia
  
  Volume: 56 Issue: 1 Pages: 11-15
- DOI
  10.14894/faruawpsj.56.1_11
- NAID
  130007779039
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Journal Article] Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence2019
- Author(s)
  Arata Y, Watanabe A, Motosugi R, Murakami R, Goto T, Hori S, Hirayama S, Hamazaki J, Murata S.
- Journal Title
  
  Genes Cells
  
  Volume: 24 Issue: 12 Pages: 801-813
- DOI
  10.1111/gtc.12728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K22526, KAKENHI-PLANNED-18H05500, KAKENHI-PUBLICLY-19H04801, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-18H04025, KAKENHI-PROJECT-19K16601
[Journal Article] Shigella effector IpaH4.5 targets 19S regulatory subunit RPN13 in the 26S proteasome to dampen cytotoxic T lymphocyte activation.2019
- Author(s)
  Otsubo R, Mimura H, Ashida H, Hamazaki J, Murata S, Sasakawa C.
- Journal Title
  
  Cell Microbiol.
  
  Volume: 21 Issue: 3 Pages: e12974-e12974
- DOI
  10.1111/cmi.12974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-16H05186, KAKENHI-PROJECT-26000014
[Journal Article] Thymoproteasome and peptidic self2019
- Author(s)
  Takahama Y, Ohigashi I, Murata S, Tanaka K.
- Journal Title
  
  Immunogenetics
  
  Volume: 71 Issue: 3 Pages: 217-221
- DOI
  10.1007/s00251-018-1081-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014
[Journal Article] FAM48A mediates compensatory autophagy induced by proteasome impairment.2019
- Author(s)
  Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S.
- Journal Title
  
  Genes Cells
  
  Volume: 24 Issue: 8 Pages: 559-568
- DOI
  10.1111/gtc.12708
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-17H06418, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-17K15445, KAKENHI-PROJECT-17H06164, KAKENHI-PLANNED-15H05903
[Journal Article] Trans-omics impact of thymoproteasome in cortical thymic epithelial cells.2019
- Author(s)
  Ohigashi I, Tanaka Y, Kondo K, Fujimori S, Kondo H, Palin A, Hoffmann V, Kozai M, Matsushita Y, Uda S, Motosugi R, Hamazaki J, Kubota H, Murata S, Tanaka K, Katagiri T, Kosako H, Takahama Y
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 9 Pages: 2901-2916
- DOI
  10.1016/j.celrep.2019.10.079
- NAID
  120006894616
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PLANNED-17H06419, KAKENHI-PUBLICLY-18H04801, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18H02431, KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-16H06577
[Journal Article] Dynamic Regulation of Proteasome Expression2019
- Author(s)
  Motosugi Ryo、Murata Shigeo
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 6
- DOI
  10.3389/fmolb.2019.00030
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022
[Journal Article] Restricted Expression of the Thymoproteasome Is Required for Thymic Selection and Peripheral Homeostasis of CD8+ T Cells2019
- Author(s)
  Tomaru Utano、Konno Saori、Miyajima Syota、Kimoto Rikuto、Onodera Mari、Kiuchi Shizuka、Murata Shigeo、Ishizu Akihiro、Kasahara Masanori
- Journal Title
  
  Cell Reports
  
  Volume: 26 Issue: 3 Pages: 639-651
- DOI
  10.1016/j.celrep.2018.12.078
- NAID
  120006595593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02629, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] In-depth Analysis of the Lid Subunits Assembly Mechanism in Mammals2019
- Author(s)
  Bai Minghui、Zhao Xian、Sahara Kazutaka、Ohte Yuki、Hirano Yuko、Kaneko Takeumi、Yashiroda Hideki、Murata Shigeo
- Journal Title
  
  Biomolecules
  
  Volume: 9 Issue: 6 Pages: 213-213
- DOI
  10.3390/biom9060213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022
[Journal Article] Specific modification of aged proteasomes revealed by tag-exchangeable knock-in mice.2018
- Author(s)
  Tomita, T., Hirayama, S., Sakurai, Y., Ohte, Y., Yoshihara, H., Saeki, Y., Hamazaki, J., and Murata, S.
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 39 Issue: 1
- DOI
  10.1128/mcb.00426-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Transcriptional regulation of the 26S proteasome by Nrf12018
- Author(s)
  Koizumi S, Hamazaki J, Murata S.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 94 Issue: 8 Pages: 325-336
- DOI
  10.2183/pjab.94.021
- NAID
  130007497652
- ISSN
  0386-2208, 1349-2896
- Year and Date
  2018-10-11
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] PAC1-PAC2 proteasome assembly chaperone retains the core α4-α7 assembly intermediates in the cytoplasm.2018
- Author(s)
  Wu W, Sahara K, Hirayama S, Zhao X, Watanabe A, Hamazaki J, Yashiroda H, Murata S.
- Journal Title
  
  Gene to Cells
  
  Volume: 10 Issue: 10 Pages: 839-848
- DOI
  10.1111/gtc.12631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K07342, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] The immunoproteasome and thymoproteasome: functions, evolution and human disease2018
- Author(s)
  Murata S, Takahama Y, Kasahara M, Tanaka K
- Journal Title
  
  Nature Immunol.
  
  Volume: 19 Issue: 9 Pages: 923-931
- DOI
  10.1038/s41590-018-0186-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Nuclear export of ubiquitinated proteins via the UBIN-POST system2018
- Author(s)
  S. Hirayama, M. Sugihara, D. Morito, S. Iemura, T. Natsume, K. Nagata
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: in press Issue: 18
- DOI
  10.1073/pnas.1711017115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-16K20998, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-18H04002, KAKENHI-PROJECT-26000014
[Journal Article] Human thymoproteasome variations influence CD8 T cell selection.2017
- Author(s)
  Takeshi Nitta, Yuta Kochi, Ryunosuke Muro, Yoshihiko Tomofuji, Tadashi Okamura, Shigeo Murata, Harumi Suzuki, Takayuki Sumida, Kazuhiko Yamamoto, Hiroshi Takayanagi
- Journal Title
  
  Science Immunology
  
  Volume: 2 Issue: 12 Pages: 5-165
- DOI
  10.1126/sciimmunol.aan5165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19102, KAKENHI-PUBLICLY-17H05788, KAKENHI-PROJECT-16K14648, KAKENHI-PROJECT-15H05703, KAKENHI-PROJECT-26000014
[Journal Article] Early and consistent overexpression of ADRM1 in ovarian high-grade serous cartinoma.2017
- Author(s)
  Jiang RT, Yemelyanova A, Xing D, Anchoori RK, Hamazaki J, Murata S, Seidman JD, Wang TL, Roden RBS.
- Journal Title
  
  Jounal of Ovarian Research
  
  Volume: 10 Issue: 1 Pages: 53-53
- DOI
  10.1186/s13048-017-0347-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] A human PSMB11 variant affects thymoproteasome processing and CD8+ T cell production2017
- Author(s)
  Ohigashi I, Ohte Y, Setoh K, Nakase H, Maekawa A, Kiyonari H, Hamazaki Y, Sekai M, Sudo T, Tabara Y, Sawai H, Omae Y, Yuliwulandari R, Tanaka Y, Mizokami M, Inoue H, Kasahara M, Minato N, Tokunaga K, Tanaka K, Matsuda F, Murata S, Takahama Y.
- Journal Title
  
  JCI Insight
  
  Volume: 2 Issue: 10 Pages: 1-14
- DOI
  10.1172/jci.insight.93664
- NAID
  120006733720
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08884, KAKENHI-PROJECT-15K19125, KAKENHI-PUBLICLY-15H01154, KAKENHI-PLANNED-24111008, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-17H04123, KAKENHI-PROJECT-15K15151, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-15H04716
[Journal Article] Foxn1-β5t transcriptional axis controls CD8+ T cell production in the thymus.2017
- Author(s)
  Uddin MM, Ohigashi I, Motosugi R, Nakayama T, Sakata M, Hamazaki J, Nishito Y, Rode I, Tanaka K, Takemoto T, Murata S, Takahama Y.
- Journal Title
  
  Nat Commun
  
  Volume: 8 Issue: 1 Pages: 14419-14419
- DOI
  10.1038/ncomms14419
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-16H02630, KAKENHI-PROJECT-15K19130, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.2017
- Author(s)
  Lu X, Nowicka U, Sridharan V, Liu F, Ramdles L, Hymel D, Dyba M, Tarasov SG, Tarasova NI, Zhao XZ, Hamazaki J, Murata S, Burke TR Jr, Walters KJ.
- Journal Title
  
  nature communications
  
  Volume: 8 Issue: 1 Pages: 15540-15540
- DOI
  10.1038/ncomms15540
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin-Binding Protein CG5445 Suppresses Aggregation and Cytotoxicity of Amyotrophic Lateral Sclerosis-linked TDP-43 in Drosophila.2017
- Author(s)
  Uechi H, Kuranaga E, Iriki T, Takano K, Hirayama S, Miura M, Hamazaki J, Murata S.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 3 Issue: 3
- DOI
  10.1128/mcb.00195-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-17K19884, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-16K20998, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells2017
- Author(s)
  Matsudaira, T., K. Mukai, T. Noguchi, J. Hasegawa, T. Hatta, S. Iemura, T. Natsume, N. Miyamura, H. Nishina, J. Nakayama, K. Semba, T. Tomita, S. Murata, H. Arai, and T. Taguchi
- Journal Title
  
  Nature Communications
  
  Volume: 8(1) Issue: 1 Pages: 651-651
- DOI
  10.1038/s41467-017-01255-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15445, KAKENHI-PLANNED-15H05903, KAKENHI-PUBLICLY-17H05996, KAKENHI-PLANNED-17H06418, KAKENHI-PLANNED-26114005, KAKENHI-PROJECT-16H04782, KAKENHI-PROJECT-17H03982, KAKENHI-PROJECT-26000014, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H06164
[Journal Article] Essential role of specialized proteasome subunits in thymic selection of CD8 T cells2016
- Author(s)
  Kincaid, E. Z. Murata, S., Tanaka, K., and Rock, K. L.
- Journal Title
  
  Nat Immunol
- Description
  【掲載確定】 in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Journal Article] Essential role of specialized proteasome subunits in thymic selection of CD8 T cells.2016
- Author(s)
  Kincaid, E. Z., Murata, S., Tanaka, K., and Rock, K. L.
- Journal Title
  
  Nature Immunology
  
  Volume: 17 Issue: 8 Pages: 938-945
- DOI
  10.1038/ni.3480
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction.2016
- Author(s)
  Koizumi S, Irie T, Hirayama S, Sakurai Y, Yashiroda H, Naguro I, Ichijo H, Hamazaki J, Murata S.
- Journal Title
  
  Elife
  
  Volume: 18357 Pages: 18357-18357
- DOI
  10.7554/elife.18357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15J01930, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-16K15115, KAKENHI-PROJECT-16K20998, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-26114009
[Journal Article] TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells2015
- Author(s)
  Takada K, Van Laethem F, Xing Y, Akane K, Suzuki H, Murata S, Tanaka K, Jameson SC, Singer A, Takahama Y.
- Journal Title
  
  Nature Immunology
  
  Volume: 16 Issue: 10 Pages: 1069-1076
- DOI
  10.1038/ni.3237
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460576, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Identification of minimum Rpn4-responsive elements in genes related to proteasome functions2015
- Author(s)
  Shirozu R, Yashiroda H, Murata S
- Journal Title
  
  FEBS Lett
  
  Volume: 589 Pages: 933-940
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25221102
[Journal Article] Muscle Segment Homeobox Genes Direct Embryonic Diapause by Limiting Inflammation in the Uterus.2015
- Author(s)
  Cha, J., Burnum-Johnson, K.E., Bartos, A., Li, Y., Baker, ES., Tilton, S.C., Webb-Robertson, B.J., Piehowski, P.D., Monroe, M.E., Jegga, A.G., Murata, S., Hirota, Y., Dey, S.K.
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 24 Pages: 15337-15349
- DOI
  10.1074/jbc.m115.655001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10660, KAKENHI-ORGANIZER-25112001, KAKENHI-PUBLICLY-26112506, KAKENHI-PUBLICLY-26112703, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-15K15596, KAKENHI-PROJECT-15K15597, KAKENHI-PROJECT-24689062, KAKENHI-PROJECT-26000014
[Journal Article] Thymoproteasomes produce unique peptide motifs for positive selection of CD8(+) T cells.2015
- Author(s)
  Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, Takahama Y, Murata S.
- Journal Title
  
  Nature Communications
  
  Volume: 6 Issue: 1 Pages: 7484-7484
- DOI
  10.1038/ncomms8484
- NAID
  120006999409
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460576, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-14J12345, KAKENHI-PROJECT-26000014
[Journal Article] Mutations in the deubiquitinase gene USP8 cause Cushing’s disease2015
- Author(s)
  Reincke M, Sbiera S, Hayakawa A, Theodoropoulou M, Osswald A, Beuschlein F, Meitinger T, Mizuno-Yamasaki E, Kawaguchi K, Saeki Y, Tanaka K, Wieland T, Graf E, Saeger W, Ronchi CL, Allolio B, Buchfelder M, Strom TM, Fassnacht M & Komada M
- Journal Title
  
  Nat. Genet.
  
  Volume: 47 Issue: 1 Pages: 31-38
- DOI
  10.1038/ng.3166
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112003, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26000014
[Journal Article] Sirt1-deficiency causes defective protein quality control2015
- Author(s)
  Tomita T, Hamazaki J, Hirayama S, McBurney MW, Yashiroda H, Murata S
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 12613-12613
- DOI
  10.1038/srep12613
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111704, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-13J10370, KAKENHI-PROJECT-26000014
[Journal Article] Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells2015
- Author(s)
  Katsuhiro Sasakil, Kensuke Takada, Yuki Ohte, Hiroyuki Kondo, Hiroyuki Sorimachi, Keiji Tanaka, Yousuke Takahama, Shigeo Murata
- Journal Title
  
  Nat Commun. in press
- NAID
  120006999409
- Description
  印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26000014
[Journal Article] N-terminal α7 deletion of the proteasome 20S core particle substitutes for yeast PI31 function.2015
- Author(s)
  Yashiroda H, Toda Y, Otsu S, Takagi K, Mizushima T, Murata S.
- Journal Title
  
  Mol Cell Biol
  
  Volume: 35(1) Issue: 1 Pages: 141-52
- DOI
  10.1128/mcb.00582-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570208, KAKENHI-PROJECT-25870631, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Proteasome Impairment Induces Recovery of Mitochondrial Membrane Potential and an Alternative Pathway of Mitochondrial Fusion2015
- Author(s)
  Shirozu R, Yashiroda H, Murata S
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 36 Issue: 2 Pages: 347-362
- DOI
  10.1128/mcb.00920-15
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26111704, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Identification of minimum Rpn4-responsive elements in genes related to proteasome functions. Shirozu R, Yashiroda H, *Murata S2015
- Author(s)
  Shirozu R, Yashiroda H, Murata S
- Journal Title
  
  FEBS Letter
  
  Volume: 589 Issue: 8 Pages: 933-940
- DOI
  10.1016/j.febslet.2015.02.025
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Redundant roles of Rpn10 and Rpn13 in recognition of ubiquitinated proteins and cellular homeostasis.2015
- Author(s)
  Hamazaki J, Hirayama S, Murata S. Redundant roles of Rpn10 and Rpn13 in recognition of ubiquitinated proteins and cellular homeostasis.
- Journal Title
  
  PLoS Genet.
  
  Volume: 11 Issue: 7 Pages: e1005401-e1005401
- DOI
  10.1371/journal.pgen.1005401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111010, KAKENHI-PUBLICLY-26111704, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] The thymic cortical epithelium determines the TCR repertoire of IL-17-producing gdT cells.2015
- Author(s)
  Nitta T, Muro R, Shimizu Y, Nitta S, Oda H, Ohte Y, Goto M, Yanobu R, Narita T, Takayanagi H, Yasuda H, Okamura T, Murata T, Suzuki H.
- Journal Title
  
  EMBO Rep.
  
  Volume: なし Issue: 5 Pages: 638-653
- DOI
  10.15252/embr.201540096
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25111516, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-14J40182, KAKENHI-PROJECT-25871164, KAKENHI-PROJECT-26000014
[Journal Article] Phosphorylated ubiquitin chain is the genuine Parkin receptor.2015
- Author(s)
  K. Okatsu, F. Koyano, M. Kimura, H. Kosako, Y. Saeki, K. Tanaka and N. Matsuda
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 209 Issue: 1 Pages: 111-128
- DOI
  10.1083/jcb.201410050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] Characterization of Testis-Specific Proteasome Subunit α4s in Mammals2014
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, and Shigeo Murata
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 18 Pages: 12365-12374
- DOI
  10.1074/jbc.m114.558866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10397, KAKENHI-PROJECT-24590075, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-26111010
[Journal Article] The mechanism for molecular assembly of the proteasome.2014
- Author(s)
  Sahara K, Kogleck L, Yashiroda H, Murata S.
- Journal Title
  
  Adv Biol Regul.
  
  Volume: 54 Pages: 51-8
- DOI
  10.1016/j.jbior.2013.09.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570208, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Quantitative live-cell imaging reveals spatiotemporal dynamics and cytoplasmic assembly of the 26S proteasome2014
- Author(s)
  Pack, Chan-Gi., Yukii, H., Toh-e, A., Kudo, T., Tsuchiya, H., Kaiho, A., Sakata, E., Murata, S., Yokosawa, H., Sako, Y., Baumeister, W., Tanaka, K., and Saeki, Y
- Journal Title
  
  Nat Commun.
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome α-ring formation2014
- Author(s)
  Takagi, K., Saeki, Y., Yashiroda, H., Yagi, H., Kaiho, A., Murata, S., Yamane, T., Tanaka, K., Mizushima, T. and Kato, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 450 Issue: 2 Pages: 1110-1114
- DOI
  10.1016/j.bbrc.2014.06.119
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24570208, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-25870631, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26293018
[Journal Article] Assembly mechanisms of specialized core particles of the proteasome.2014
- Author(s)
  Bai M, Zhao X, Sahara K, Ohte Y, Hirano Y, Kaneko T, Yashiroda H, Murata S.
- Journal Title
  
  Biomolecules.
  
  Volume: 4(3) Issue: 3 Pages: 662-77
- DOI
  10.3390/biom4030662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24570208, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome2014
- Author(s)
  Pack, CG., Yukii, H.,　Toh-e, A., Kudo, T., Tsuchiya, H., Kaiho, A., Sakata, E., Murata, S., Sako, Y., Baumeister, W., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Nature Commun
  
  Volume: 5 Issue: 1 Pages: 3396-3396
- DOI
  10.1038/ncomms4396
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657097, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Quantitative live-cell imagingreveals moleculardynamics andcytoplasmic assembly ofthe 26Sproteasome2014
- Author(s)
  Pack, Chan-Gi., Yukii, H., Toh-e, A., Kudo,T., Tsuchiya, H., Kaiho, A., Sakata, E., Murata, S., Yokosawa, H., Sako, Y., Baumeister, W., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Nat Commun.
  
  Volume: 2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells2013
- Author(s)
  Sasaki, Y., Sano, S., Nakahara, M., Murata, S., Kometani, K., Aiba, Y., Sakamoto, S., Watanabe, Y., Tanaka, K., Kurosaki, T., and lwai, K.
- Journal Title
  
  EMBO J.
  
  Volume: 32 Issue: 18 Pages: 2463-2476
- DOI
  10.1038/emboj.2013.184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21229007, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-24659136, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-25253019
[Journal Article] Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells.2013
- Author(s)
  Ohigashi, I., Zuklys, S., Sakata, M., Mayer, GE., Zhanybekova. S., Murata, S., Tanaka, K., Hollander, G., and Takahama, Y.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 110 Issue: 24 Pages: 9885-9890
- DOI
  10.1073/pnas.1301799110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23249025, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-25860361
[Journal Article] Keratin 8 Is Required for the Maintenance of Architectural Structure in Thymus Epithelium.2013
- Author(s)
  Odaka, C.
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 9 Pages: 75101-75101
- DOI
  10.1371/journal.pone.0075101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23247035, KAKENHI-PLANNED-24113005, KAKENHI-PROJECT-25221102
[Journal Article] Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells.2013
- Author(s)
  Ohigashi, I., Zuklys, S., Sakata, M., Mayer, GE., Zhanybekova. S., Murata, S., Tanaka, K., Hollander, G., and Takahama, Y.
- Journal Title
  
  Proc Natl Acad Sci USA in press.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Proteasome dysfunction mediates obesity-induced endoplasmic reticulum stress and insulin resistance in the liver2013
- Author(s)
  T Otoda, T Takamura, H Misu, T Ota, S Murata, H Hayashi, H Takayama, A Kikuchi, T Kanamori, KR Shima, F Lan, T Takeda, S Kurita, K Ishikura, Y Kita, K Iwayama, KI Kato, M Uno, Y Takeshita, M Yamamoto, K Tokuyama, S Iseki, K Tanaka, S Kaneko
- Journal Title
  
  Diabetes
  
  Volume: 62(3) Issue: 3 Pages: 811-24
- DOI
  10.2337/db11-1652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249042, KAKENHI-PROJECT-23591301, KAKENHI-PROJECT-23791022, KAKENHI-PROJECT-25282017
[Journal Article] Involvement of Bag6 and theTRC pathwayin proteasome assembly2013
- Author(s)
  Akahane, T., Sahara, K., Yashiroda, H., Tanaka, K., andMurata, S.
- Journal Title
  
  Nat Commun.
  
  Volume: 4 Issue: 1 Pages: 2234-2234
- DOI
  10.1038/ncomms3234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-24570208, KAKENHI-PROJECT-25221102
[Journal Article] Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver2013
- Author(s)
  Otoda T, Takamura T, Misu H, Ota T, Murata S, Hayashi H, Takayama H, Kikuchi A, Kanamori T, Shima KR, Lan F, Takeda T, Kurita S, Ishikura K, Kita Y, Iwayama K, Kato KI, Uno M, Takeshita Y, Yamamoto M, Tokuyama K, Iseki S, Tanaka K, Kaneko S
- Journal Title
  
  Diabetes
  
  Volume: 62 Pages: 811-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591301
[Journal Article] Thymic nurse cells do not nurse most T cells but support TCR revision in cortical thymocytes.2012
- Author(s)
  Nakagawa, Y., Ohigashi, I., Nitta, T., Tanaka, K., Murata, S., Sakata, M., and Takahama, Y.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Pages: 20572-20577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] β5t-containing thymoproteasome : thymic cortical epithelial cell-specific expression and role in positive selection of CD8^+ T cells2012
- Author(s)
  Takahama, Y., Takada, K., Murata, S., Tanaka, K.
- Journal Title
  
  Curr.Opini.Immunol.
  
  Volume: 24 Pages: 92-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities.2012
- Author(s)
  Tomaru U, Takahashi S, Ishizu A, Miyatake Y, Gohda A, Suzuki S, Ono A, Ohara J, Baba T, Murata S, Tanaka K, and Kasahara M.
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 180 Pages: 963-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Using siRNA techniques to dissectproteasome assembly pathways in mammaliancells2012
- Author(s)
  Kaneko T, Murata S
- Journal Title
  
  Methods Mol Biol
  
  Volume: 832 Pages: 433-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790060
[Journal Article] Decreased proteasomal activity causes age-related phenotypes and promotes the development of metabolic abnormalities2012
- Author(s)
  Tomaru U, Takahashi S, Ishizu A, Miyatake Y, Gohda A, Suzuki S, Ono A, Ohara J, Baba T, Murata S, Tanaka K, Kasahara M
- Journal Title
  
  Am.J.Pathol.
  
  Volume: 180 Issue: 3 Pages: 963-972
- DOI
  10.1016/j.ajpath.2011.11.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21390112, KAKENHI-PROJECT-22590353, KAKENHI-PROJECT-23657083, KAKENHI-PROJECT-23659195, KAKENHI-PROJECT-23790430, KAKENHI-PROJECT-23790532, KAKENHI-PROJECT-24390091, KAKENHI-PROJECT-24659171
[Journal Article] β5t-containing thymoproteasome: thymic cortical epithelial cell-specific expression and role in positive selection of CD8+ T cells.2012
- Author(s)
  Takahama, Y., Takada, K., Murata, S., and Tanaka, K.
- Journal Title
  
  Curr. Opini. Immunol.
  
  Volume: 24 Pages: 92-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit beta5t2011
- Author(s)
  Mat Ripen A
- Journal Title
  
  European Journal of Immunology
  
  Volume: 41 Issue: 5 Pages: 1278-1287
- DOI
  10.1002/eji.201041375
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19059010, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23249025
[Journal Article] Ontogeny of thymic cortical epithelial cells expressing thymoproteasome subunit β5t.2011
- Author(s)
  Ripen, AM., Nitta, T., Murata, S., Tanaka, K., Takahama, Y.
- Journal Title
  
  Eur.J.Immunol.
  
  Volume: 32 Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Assembly defect due to a PSMB8 mutation reduces proteasome activity and causes the autoinflammatory disorder, Nakajo-Nishimura syndrome2011
- Author(s)
  Arima, K., Kinoshita, A., Mishima, H., Kanazawa, N., Kaneko, T., Mizushima, T., Ichinose, K., Nakamura, H., Tsujino, A., Kawakami, A., Matsunaka, M., Kasagi, S., Kawano, S., Kumagai, S., Ohmura, K., Mimori, T., Hirano, M., Ueno, S., Tanaka, K., Tanaka, M., Toyoshima, I., Sugino, H., Yamakawa, A., Tanaka, K., Niikawa, N., Furukawa, F., Murata, S., Eguchi, K., Ida, H., Yoshiura, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA
  
  Volume: 108 Issue: 36 Pages: 14914-14919
- DOI
  10.1073/pnas.1106015108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21591097, KAKENHI-PROJECT-22591094, KAKENHI-PROJECT-22659071, KAKENHI-PROJECT-23500455, KAKENHI-PROJECT-23591651, KAKENHI-PROJECT-23657083, KAKENHI-PROJECT-23791115, KAKENHI-PROJECT-23791230
[Journal Article] Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme.2011
- Author(s)
  Oh, K.H., Yang, S.W., Park, J.M., Seol, J.H., Iemura, S., Natsume, T., Murata, S., Tanaka, K., Jeon, Y.J., Chung, C.H.
- Journal Title
  
  Cell Death and Differ.
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme2011
- Author(s)
  Oh, K.H., Yang, S.W., Park, J.M., Seol, J.H., Iemura, S., Natsume, T., Murata, S., Tanaka, K., Jeon, Y.J., Chung, C.H.
- Journal Title
  
  Cell Death Differ.
  
  Volume: 18 Issue: 8 Pages: 1326-1336
- DOI
  10.1038/cdd.2011.3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans2011
- Author(s)
  Kitamura A, Maekawa Y, Uehara H, Izumi K, Kawachi I, Nishizawa M, Toyoshima Y, Takahashi H, Standley DM, Tanaka K, Hamazaki J, Murata S, Obara K, Toyoshima I, Yasutomo K.
- Journal Title
  
  J Clin Invest
  
  Volume: 121 Issue: 10 Pages: 4150-4160
- DOI
  10.1172/jci58414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679005, KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21570169, KAKENHI-PROJECT-21590536, KAKENHI-PROJECT-23591236, KAKENHI-PROJECT-23657083, KAKENHI-PROJECT-23791179
[Journal Article] Thymoproteasome shapes immunocompetent repertoire of CD8 T cells.2010
- Author(s)
  Nitta, T., Murata, S., Sasaki, K., Fujii, H., Ripen, A.M., Ishimaru, N., Koyasu, S., Tanaka, K., Takahama, Y.
- Journal Title
  
  Immunity
  
  Volume: 32 Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t.2010
- Author(s)
  Florea, B.I., Verdoes, M., Li, N., van den Linden, W.A., Geurink, P.P., van den Elst, H., Hofmann, T., de Ru, A., van Veelen, P.A., Tanaka, K., Sasaki, K., Murata, S., den Dulk, H., Brouwer, J., Ossendorp, F.A., Kisselev, A.F., Overkleeft, H.S.
- Journal Title
  
  Chem Biol.
  
  Volume: 17 Pages: 795-801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Genetic immunization based on the ubiquitin-fusion degradation pathway against Trypanosoma cruzi2010
- Author(s)
  Chou B, Hiromatsu K, Hisaeda H, Duan X, Imai T, Murata S, Tanaka K, Himeno K
- Journal Title
  
  Biochem Biophys Res Commun 392
  
  Pages: 277-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells2010
- Author(s)
  Nitta T, Murata S, Sasaki K, Fujii H, Ripen AM, Ishimaru N, Koyasu S, Tanaka K, Takahama Y
- Journal Title
  
  Immunity 32
  
  Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and importance of latent 20S proteasomes in maintaining cellular homeostasis.2010
- Author(s)
  Sasaki, K., Hamazaki, J., Koike, M., Hirano, Y., Komatsu, M., Uchiyama, Y., Tanaka, K., Murata, M.
- Journal Title
  
  Mol Cell.Biol.
  
  Volume: 30 Pages: 3864-3874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] CHIP-dependent termination of MEKK2 regulates temporal ERK activation required for proper hyperosmotic response.2010
- Author(s)
  Maruyama, T., Kadowaki, H., Okamoto, N., Nagai, A., Naguro, I., Matsuzawa, A., Shibuya, H., Tanaka, K., Murata, S., Takeda, K., Nishito, h H., Ichijo, H.
- Journal Title
  
  EMBO J.
  
  Volume: 9 Pages: 2501-2514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Role of thymic cortex-specific self-peptides in positive selection of T cells.2010
- Author(s)
  Takahama, Y., Nitta, T., Ripen, A.M., Nitta, S., Murata, M., Tanaka, K.
- Journal Title
  
  Semin.Immunol.
  
  Volume: 22 Pages: 287-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Thymoproteasome shapes immunocompetent repertoire of CD8 T cells2010
- Author(s)
  Nitta, T., Murata, S., Sasaki, K., Fujii, H., Ripen, A. M., Ishimaru, N., Koyasu, S., Tanaka, K., and Takahama, Y.
- Journal Title
  
  Immunity
  
  Volume: 32 Pages: 29-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Assembly pathway of the mammalian proteasome base subcomplex is mediated by multiple specific chaperones2009
- Author(s)
  Kaneko, T., Hamazaki, J., Iemura, S., Sasaki, K., Furuyama, K., Natsume, T., Tanaka, K., and Murata, S.
- Journal Title
  
  Cell
  
  Volume: 137 Pages: 914-925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process2009
- Author(s)
  Tonoki A, Kuranaga E, Tomioka T, Hamazaki J, Murata S, Tanaka K, Miura M
- Journal Title
  
  Mol Cell Biol 29
  
  Pages: 1095-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymic environments of T-cell repertoire formation.2009
- Author(s)
  Nitta, T., Murata, S., Ueno, T., Tanaka, K., and Takahama, Y.
- Journal Title
  
  Adv Immunol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Molecular mechanisms of proteasome assembly.2009
- Author(s)
  Murata, S., Yashiroda, H., and Tanaka, K.
- Journal Title
  
  Nat Rev Mol Cell Biol 10
  
  Pages: 104-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Genetic evidence linking age-dependent attenuation of the 26S proteasome with aging process.2009
- Author(s)
  Tonoki, A., Kuranaga, E., Tomioka, T., Hamazaki, J., Murata, S., Tanaka, K., and Miura. M.
- Journal Title
  
  Mol Cell Biol. 29
  
  Pages: 1095-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] An inhibitor of deubiquitinating enzyme regulates ubiquitin homeostasis2009
- Author(s)
  Kimura, Y., Yashiroda, H., Kudo, T., Koitabashi, S., Murata, S., Kakizuka, A., and Tanaka, K.
- Journal Title
  
  Cell
  
  Volume: 137 Pages: 549-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012
[Journal Article] Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation2009
- Author(s)
  Tokunaga F, Sakata S, Saeki Y, Satomi Y, Kirisako T, Kamei K, Nakagawa T, Kato M, Murata S, Yamaoka S, et al.
- Journal Title
  
  Nat Cell Biol 11
  
  Pages: 123-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] 17-DMAG ameliorates polyglutamine-mediated motor neuron degeneration through well-preserved proteasome function in an SBMA model mouse2009
- Author(s)
  Tokui K, Adachi H, Waza M, Katsuno M, Minamiyama M, Doi H, Tanaka K, Hamazaki J, Murata S, Tanaka F, et al.
- Journal Title
  
  Hum Mol Genet 18
  
  Pages: 898-910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Linear ubiquitination of NEMO triggers NF-κB activation.2009
- Author(s)
  Tokunaga, T., Sakata, S., Satomi, Y., Kirisako, T., Kamei, K., Nakagawa, T., Murata, S., Yamaoka, S., Takao, T., Tanaka, K., and Iwai K.
- Journal Title
  
  Nature Cell Biol. 11
  
  Pages: 123-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Exclusive expression of proteasome subunit {beta}5t in the human thymic cortex2009
- Author(s)
  Tomaru U, Ishizu A, Murata S, Miyatake Y, Suzuki S, Takahashi S, Kazamaki T, Ohara J, Baba T, Iwasaki S, et al.
- Journal Title
  
  Blood 113
  
  Pages: 5186-5191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Molecular mechanisms of proteasome assembly2009
- Author(s)
  Murata, S.
- Journal Title
  
  Nature Reviews Molecular and Cellular Biology 10
  
  Pages: 104-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones2009
- Author(s)
  Kaneko T, Hamazaki J, Iemura S, Sasaki K, Furuyama K, Natsume T, Tanaka K, Murata S
- Journal Title
  
  Cell 137
  
  Pages: 914-925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] An inhibitor of deubiquitinating enzyme regulates ubiquitin homeostasis.2009
- Author(s)
  Kimura, Y., Yashiroda, H., Kudo, T., Koitabashi, S., Murata, S., Kakizuka, A., and Tanaka, K.
- Journal Title
  
  Cell in press (May 1^<st>).
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Molecular mechanisms of proteasome assembly2009
- Author(s)
  Murata S, Yashiroda H, Tanaka K
- Journal Title
  
  Nat Rev Mol Cell Biol 10
  
  Pages: 104-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Molecular mechanisms of proteasome assembly.2009
- Author(s)
  Murata, S., Yashiroda, H., Tanaka, K.
- Journal Title
  
  Nat Rev Mol Cell Biol 10
  
  Pages: 104-115
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection.2009
- Author(s)
  Tu L, Moriya C, Imai T, Ishida H, Tetsutani K, Duan X, Murata S, Tanaka K, Shimokawa C, Hisaeda H, et al.
- Journal Title
  
  Eur J Immunol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] An inhibitor of deubiquitinating enzyme regulates ubiquitin homeostasis.2009
- Author(s)
  Kimura, Y., Yashiroda, H., Kudo, T., Koitabashi, S., Murata, S., Kakizuka, A., Tanaka, K.
- Journal Title
  
  Cell 137
  
  Pages: 549-559
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] The 20S proteasome as an assembly platform for the 19S regulatory complex2009
- Author(s)
  Hendil KB, Kriegenburg F, Tanaka K, Murata S, Lauridsen AM, Johnsen AH, Hartmann-Petersen R
- Journal Title
  
  J Mol Biol 394
  
  Pages: 320-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Assembly pathway of the mammalian proteasome base subcomplex is mediated by multiple specific chaperones.2009
- Author(s)
  Kaneko, T., Hamazaki, J., Iemura, S., Sasaki, K., Furuyama, K., Natsume, T., Tanaka, K., Murata, S.
- Journal Title
  
  Cell 137
  
  Pages: 914-925
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Exclusive expression of proteasome subunit β5t in the human thymic cortex.2009
- Author(s)
  Tomaru, U., Ishizu, A., Murata, S., Miyakate, Y., Suzuki, S., Takahashi, S., Kazamaki, T., Ohara, J., Baba, T., Iwasaki, S., Fugo, K., Otsuka, N., Tanaka, K., and Kasahara, M.
- Journal Title
  
  Blood in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] An inhibitor of a deubiquitinating enzyme regulates ubiquitin homeostasis2009
- Author(s)
  Kimura Y, Yashiroda H, Kudo T, Koitabashi S, Murata S, Kakizuka A, Tanaka K
- Journal Title
  
  Cell 137
  
  Pages: 549-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Crystal structure of the de-ubiquitinating enzyme UCH37 (human UCH-L5) catalytic domain2009
- Author(s)
  Nishio K, Kim SW, Kawai K, Mizushima T, Yamane T, Hamazaki J, Murata S, Tanaka K, Morimoto Y
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 855-860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymoproteasome:probable role in generating positively selecting peptides2008
- Author(s)
  Murata, S
- Journal Title
  
  Curr Opin Immunol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymic microenvironments for T-cell repertoire formation2008
- Author(s)
  Nitta T, Murata S, Ueno T, Tanaka K, Takahama Y
- Journal Title
  
  Adv Immunol 99
  
  Pages: 59-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymoproteasome: probable role in generating positively selecting peptides.2008
- Author(s)
  Murata, S., Takahama, Y., Tanaka, K.
- Journal Title
  
  Curr Opini Immunol 20
  
  Pages: 192-196
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Critical contribution of immunoproteasomes in the induction of protective immunity against Trypanosoma cruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein2008
- Author(s)
  Chou B, Hisaeda H, Shen J, Duan X, Imai T, Tu L, Murata S, Tanaka K, Himeno K
- Journal Title
  
  Microbes Infect 10
  
  Pages: 241-250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Allele-selective effect of PA28 in MHC class I antigen processing2008
- Author(s)
  Yamano T, Sugahara H, Mizukami S, Murata S, Chiba T, Tanaka K, Yui K, Udono H
- Journal Title
  
  J Immunol 181
  
  Pages: 1655-1664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes.2008
- Author(s)
  Yashiroda, H., Mizushima, T., Okamoto, K., Kameyama, T., Hayashi, H., Kishimoto, T., Kasahara, M., Kurimoto, E., Sakata, E., Suzuki, A., Hirano, Y., Murata, S., Kato, K., Yamane, T., Tanaka, K.
- Journal Title
  
  Nat Struct Mol Biol 15
  
  Pages: 228-236
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Thymoproteasome : probable role in generating positively selecting peptides2008
- Author(s)
  Murata, S.
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 192-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Modest cortex and promiscuous medulla for thymic repertoire formation.2008
- Author(s)
  Takahama, Y., Tanaka, K., and Murata, S.,
- Journal Title
  
  Trends Immunol 29
  
  Pages: 251-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Hsp90-mediated assembly of the 26 S proteasome is involved in major histocompatibility complex class I antigen processing2008
- Author(s)
  Yamano T, Mizukami S, Murata S, Chiba T, Tanaka K, Udono H
- Journal Title
  
  J Biol Chem 283
  
  Pages: 28060-28065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Modest cortex and promiscuous medulla for thymic repertoire formation2008
- Author(s)
  Takahama Y, Tanaka K, Murata S
- Journal Title
  
  Trends Immunol 29
  
  Pages: 251-255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymoproteasome : probable role in generating positively selecting peptides2008
- Author(s)
  Murata, S.
- Journal Title
  
  Current Opinion in Immunology 20
  
  Pages: 192-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060036
[Journal Article] Thymoproteasome: probable role in generating positively selecting peptides2008
- Author(s)
  Murata S, Takahama Y, Tanaka K
- Journal Title
  
  Curr Opin Immunol 20
  
  Pages: 192-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Dissecting β-ring assembly pathway of the mammalian 20S proteasome.2008
- Author(s)
  Hirano, Y., Kaneko, T., Okamoto, K., Bai, M., Yashiroda, H., Furuyama, K., Kato, K., Tanaka, K., and Murata, S.
- Journal Title
  
  EMBO J. 27
  
  Pages: 2204-2213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Molecular mechanisms of proteasome assembly2008
- Author(s)
  Murata, S.
- Journal Title
  
  Nature Reviews Molecular Cell Biology 10
  
  Pages: 104-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060036
[Journal Article] -ring assembly pathway of the mammalian 20S proteasome.2008
- Author(s)
  Hirano, Y., Kaneko, T., Okamoto, K., Bai, M., Yashiroda, H., Furuyama, K., Kato, K., Tanaka, K., Murata, S.
- Journal Title
  
  EMBO J 27
  
  Pages: 2204-2213
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes.2008
- Author(s)
  Yashiroda, H., Mizushima, T., Okamoto, K., Kameyama, T., Hayashi, H., Kishimoto, T., Kasahara, M., Kurimoto, E., Sakata, E., Suzuki, A., Hirano. Y., Murata, S., Kato, K., Yamane, T., and Tanaka, K.
- Journal Title
  
  Nature Struct. Mol. Biol. 15
  
  Pages: 228-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Dissecting beta-ring assembly pathway of the mammalian 20S proteasome2008
- Author(s)
  Hirano Y, Kaneko T, Okamoto K, Bai M, Yashiroda H, Furuyama K, Kato K, Tanaka K, Murata S
- Journal Title
  
  EMBO J 27
  
  Pages: 2204-2213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Thymoproteasome : probable role in generating positively selecting peptides.2008
- Author(s)
  Murata, S., Takahama, Y., and Tanaka, K.
- Journal Title
  
  Curr Opini Immunol 20
  
  Pages: 192-196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Regulation of CD8^+ T cell development by thymus-specific proteasomes2007
- Author(s)
  Murata, S., et. al.
- Journal Title
  
  Science 316
  
  Pages: 1349-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Regulation of CD8+T cell development by thymus-specific proteasomes2007
- Author(s)
  Murata, S
- Journal Title
  
  Science 316
  
  Pages: 1349-1349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19044050
[Journal Article] Regulation of CD8+ T cell development by thymus-specific proteasomes.2007
- Author(s)
  Murata, S., Sasaki, K., Kishimoto, T., Niwa, S., Hayashi, H., Takahama, Y., Tanaka, K.
- Journal Title
  
  Science 316
  
  Pages: 1349-1353
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Regulation of CD8+ T cell development by thymusspecific proteasomes2007
- Author(s)
  Murata, S
- Journal Title
  
  Science 316
  
  Pages: 1349-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Regulation of CD8+ T cell development by thymus-specific proteasomes2007
- Author(s)
  Murata S, Sasaki K, Kishimoto T, Niwa S, Hayashi H, Takahama Y, Tanaka K
- Journal Title
  
  Science 316
  
  Pages: 1349-1353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.2007
- Author(s)
  Komatsu, M., Waguri, S., Koike, M., Sou, Y., Ueno, T., Hara, T., Mizushima, N., Iwata, J., Ezaki, J., Murata, S., Hamazaki, J., Nishito, Y., Iemura, S., Natsume, N., Yanagawa, T., Uwayama, J., Warabi, E., Yoshida, H., Ishii, T., Kobayashi, A., Yamamoto, M., Yue, Z., Uchiyama, Y., Kominami, E., Tanaka, K.
- Journal Title
  
  Cell 131
  
  Pages: 1149-1163
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice2007
- Author(s)
  Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, et al.
- Journal Title
  
  Cell 131
  
  Pages: 1149-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] Rpn10-mediated degradation of ubiquitinated proteins is essential for mouse development2007
- Author(s)
  Hamazaki J, Sasaki K, Kawahara H, Hisanaga S, Tanaka K, Murata S
- Journal Title
  
  Mol Cell Biol 27
  
  Pages: 6629-6638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19687009
[Journal Article] A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes.2006
- Author(s)
  Hamazaki, J., Iemura, S., Natsume, T., Yashiroda, H., Tanaka, K., Murata, S.
- Journal Title
  
  EMBO J. 25
  
  Pages: 4524-4536
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes.2006
- Author(s)
  Hirano, Y., Hayashi, H., Iemura, S., Hendil, K.B., Niwa, S., Kishimoto, T., Natsume, T., Kasahara, M., Tanaka, K., Murata, S.
- Journal Title
  
  Mol Cell 24
  
  Pages: 977-984
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration2006
- Author(s)
  Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., Tanaka, K.
- Journal Title
  
  Nature 441
  
  Pages: 880-884
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration.2006
- Author(s)
  Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., Tanaka, K.
- Journal Title
  
  Nature 441
  
  Pages: 880-884
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes2006
- Author(s)
  Hamazaki, J., Iemura, S., Natsume, T., Yashiroda, H., Tanaka, K., Murata, S.
- Journal Title
  
  EMBO Journal 25・19
  
  Pages: 4524-4536
- Data Source
  KAKENHI-PROJECT-17028057
[Journal Article] Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes2006
- Author(s)
  Hirano, Y., Hayashi, H., lemura, S., Hendil, K.B., Niwa, S., Kishimoto, T., Kasahara, M., Natsume, T., Tanaka, K., Murata, S.
- Journal Title
  
  Molecular Cell 24・6
  
  Pages: 977-984
- Data Source
  KAKENHI-PROJECT-17028057
[Journal Article] A novel proteasome interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes2006
- Author(s)
  Hamazaki, J., Iemura, S., Natsume, T., Yashiroda, H., Tanaka, K., Murata, S.
- Journal Title
  
  EMBO J. 25
  
  Pages: 4524-4536
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes2006
- Author(s)
  Hirano, Hayashi, H., Iemura, S., Hendil, K.B., Niwa, S., Kishimoto, T., Natsume, T., Kasahara, M., Tanaka, K., Murata, S.
- Journal Title
  
  Mol Cell 24
  
  Pages: 977-984
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes.2005
- Author(s)
  Hirano Y, HendilKB, Yashiroda H, Iemura S, Nagane R, Hioki Y, Natsume T, Tanaka K, Murata S.
- Journal Title
  
  Nature 437・7063
  
  Pages: 1381-1385
- Data Source
  KAKENHI-PROJECT-17028057
[Journal Article] A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes2005
- Author(s)
  Hirano, Y., Hendil, K.B., Yashiroda, H., Iemura, S., Nagane, R., Hioki, Y., Natsume, T., Tanaka, K., Murata, S.
- Journal Title
  
  Nature 437
  
  Pages: 1381-1385
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.2005
- Author(s)
  Komatsu, M., Waguri, S., Ueno, T., Murata, S., Tanida, I., Ezaki, E., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K., Chiba, T.
- Journal Title
  
  J. Cell Biol 169
  
  Pages: 425-434
- Data Source
  KAKENHI-PROJECT-17002019
[Journal Article] Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice2005
- Author(s)
  Komatsu, M., Waguri, S., Ueno, T., Murata, S., Tanida, I., Ezaki, E., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K., Chiba, T.
- Journal Title
  
  J. Cell Biol. 169
  
  Pages: 425-434
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] A heterodimeric complex that promotes the assembly of mammalian 20S proteasomes2005
- Author(s)
  Hirano, Y., Hendil, K.B., Yashiroda, H., Iemura, S., Nagane, R., Hioki, Y., Natsume, T., Tanaka, K., Murata, S.
- Journal Title
  
  Nature 437
  
  Pages: 1381-1385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Impairment o starvation-induced and constitutive autophagy in Atg7-deficient mice2005
- Author(s)
  Komatsu, M., Waguri, S., Ueno, T., Murata, S., Tanida, I., Ezaki, E., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K., Chiba, T.
- Journal Title
  
  J. Cell Biol. 169
  
  Pages: 425-434
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Two distinct pathways mediated by PA28 and hsp90 in MHC class I antigen processing2002
- Author(s)
  Yamano, T., Murata, S., Shimbara, N., Tanaka, N., Chiba, T., Tanaka, K., Yui, K., Udono, H.
- Journal Title
  
  J. Exp. Med. 196
  
  Pages: 185-196
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Two distinct pathways mediated by PA28 and hsp90 in MHC class I antigen processing2002
- Author(s)
  Yamano, T., Murata, S., Shimbara, N., Tanaka, N., Chiba, T., Tanaka, K.Yui, K., Udono, H.
- Journal Title
  
  J. Exp. Med. 196
  
  Pages: 185-196
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] CHIP is a chaperone-dependent E3 ligase that ubiquitylates unfolded protein2001
- Author(s)
  Murata, S., Minami, Y., Minami, M., Chiba, T., Tanaka, K
- Journal Title
  
  EMBO Rep. 2
  
  Pages: 1133-1138
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Immunoproteasome assembly and antigen processing in mice lacking both PA28a and PA28b.2001
- Author(s)
  Murata, S., Udono, H., Tanahashi, N., Hamada, N., Adachi, K., Yamano, T., Yui, K., Kobayashi, N., Kawahara, M., Tanaka, K., Chiba, T.
- Journal Title
  
  EMBO J. 20
  
  Pages: 5898-5907
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Immunoproteasome assembly and antigen processing in mice lacking both PA28a and PA28b2001
- Author(s)
  Murata, S., Udono, H., Tanahashi, N., Hamada, N., Adachi, K., Yamano, T., Yui, K., Kobayashi, N., Kasahara, M., Tanaka, K., Chiba, T.
- Journal Title
  
  EMBO J 20
  
  Pages: 5898-5907
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] CHIP is a chaperone- dependent E3 ligase that ubiquitylates unfolded protein2001
- Author(s)
  Murata, S., Minami, Y., Minami, M., Chiba, T., Tanaka, K.
- Journal Title
  
  EMBO Rep. 2
  
  Pages: 1133-1138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Impariment of starvation-induced and constitutive autophagy in Atg7-deficient mice.
- Author(s)
  Komatsu, M., Waguri, S., Ueno, T., Murata, S., Tanida, I., Ezaki, E., Mizushima, N., Ohsumi, Y., Uchiyama, Y., Kominami, E., Tanaka, K.K., Chiba, T.
- Journal Title
  
  J.Cell Biol. (In press)
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration
- Author(s)
  Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., Tanaka, K.
- Journal Title
  
  Nature (in press)(Published online 19 April 2006, doi:10.1038/ nature 04723).
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Journal Article] Loss of autophagy in the central nervous system causes neurodegeneration
- Author(s)
  Komatsu, M., Waguri, S., Chiba, T., Murata, S., Iwata, J., Ueno, T., Koike, M., Uchiyama, Y., Kominami, E., Tanaka, K
- Journal Title
  
  Nature (Published online 19 April 2006, doi : 10.1038/nature 04723). (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13002008
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  学術変革領域「マルチファセット・プロテインズ」第5回領域会議
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] 加齢依存的に蓄積するタンパク質凝集体の同定とその生理的意義の解明2023
- Author(s)
  渡邊綾香、小湊樹、平山尚志郎、高鳥翔、Juan A. Varela、富田泰輔、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  「マルチファセット・プロテインズー拡大し変容するタンパク質の世界」班会議
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity under proteasome impairment2023
- Author(s)
  Jun Kishiki, Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ESCRT-I複合体が小胞体上のコレステロール合成酵素のプロテアソーム分解に関与することの生理的意義の解明2023
- Author(s)
  平山尚志郎、松井誠杜、門禹森、小迫英尊、村田茂穂
- Organizer
  _部科学省科学研究費補助_「新学術領域研究」第5 回「マルチモードオートファジー」班会議第15 回オートファジー研究会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] 核UFD経路 E3 ligaseとMDM2の連携によるp53の分解メカニズムの解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 哺乳類プロテアソームの新規転写因子の同定2023
- Author(s)
  橋本創太、王妍、董瑶加、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第96回生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity under proteasome impairment2023
- Author(s)
  Jun Kishiki, Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 加齢依存的に蓄積するタンパク質凝集体の同定とその生理的意義の解明2023
- Author(s)
  渡邊綾香、小湊樹、平山尚志郎、高鳥翔、Juan A. Varela、富田泰輔、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 核UFD経路 E3 ligaseとMDM2の連携によるp53の分解メカニズムの解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 核UFD経路 E3 ligaseとMDM2の連携によるp53の分解メカニズムの解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  「マルチファセット・プロテインズー拡大し変容するタンパク質の世界」班会議
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソームの機能制御因子の網羅的探索2023
- Author(s)
  稲見真紀, 川邉明広, 平山尚志郎, 榎本豊, 北村俊雄, 濱崎純, 村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] ユビキチン様タンパク質FUBIによるタンパク質修飾機構とその生理的意義の解明2023
- Author(s)
  石田ちひろ、平山尚志郎、高橋宏隆、澤崎達也、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] 核UFD経路のE3リガーゼによるp53代謝制御機構の解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Identifying the neurological pool of proteins which aggregate upon aging in mice and elucidating their physiological significance.2023
- Author(s)
  Ayaka Watanabe, Shoshiro Hirayama, Itsuki Kominato, Sho Takatori, Juan A Varela, Taisuke Tomita, and Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ESCRT-I複合体が小胞体上のコレステロール合成酵素のプロテアソーム分解に関与することの生理的意義の解明2023
- Author(s)
  平山尚志郎、松井誠杜、門禹森、小迫英尊、村田茂穂
- Organizer
  _部科学省科学研究費補助_「新学術領域研究」第5 回「マルチモードオートファジー」班会議第15 回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  学術変革領域「マルチファセット・プロテインズ」第5回領域会議
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] ユビキチン様タンパク質FUBIによるタンパク質修飾機構とその生理的意義の解明2023
- Author(s)
  石田ちひろ、平山尚志郎、高橋宏隆、澤崎達也、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 加齢依存的に蓄積するタンパク質凝集体の同定とその生理的意義の解明2023
- Author(s)
  渡邊綾香、小湊樹、平山尚志郎、高鳥翔、Juan A. Varela、富田泰輔、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 哺乳類プロテアソームの新規転写因子の同定2023
- Author(s)
  橋本創太、王妍、董瑶加、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第96回生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ESCRT-I複合体は、小胞体上のコレステロール合成酵素のプロテアソーム分解に関与する2023
- Author(s)
  松井誠杜、門禹森、平山尚志郎、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ユビキチン様タンパク質FUBIによるタンパク質修飾機構とその生理的意義の解明2023
- Author(s)
  石田ちひろ、平山尚志郎、高橋宏隆、澤崎達也、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  学術変革領域「マルチファセット・プロテインズ」第5回領域会議
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 非典型的翻訳産物を含めた新規タンパク質品質管理機構のユビキトームによる可視化2023
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  「マルチファセット・プロテインズー拡大し変容するタンパク質の世界」班会議
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] ESCRT-I複合体が小胞体上のコレステロール合成酵素のプロテアソーム分解に関与することの生理的意義の解明2023
- Author(s)
  平山尚志郎、松井誠杜、門禹森、小迫英尊、村田茂穂
- Organizer
  _部科学省科学研究費補助_「新学術領域研究」第5 回「マルチモードオートファジー」班会議第15 回オートファジー研究会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Identifying the neurological pool of proteins which aggregate upon aging in mice and elucidating their physiological significance.2023
- Author(s)
  Ayaka Watanabe, Shoshiro Hirayama, Itsuki Kominato, Sho Takatori, Juan A Varela, Taisuke Tomita, and Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 核UFD経路のE3リガーゼによるp53代謝制御機構の解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity under proteasome impairment2023
- Author(s)
  Jun Kishiki, Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] Identifying the neurological pool of proteins which aggregate upon aging in mice and elucidating their physiological significance.2023
- Author(s)
  Ayaka Watanabe, Shoshiro Hirayama, Itsuki Kominato, Sho Takatori, Juan A Varela, Taisuke Tomita, and Shigeo Murata
- Organizer
  12th General Meeting of the International Proteolysis Society
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソームの機能制御因子の網羅的探索2023
- Author(s)
  稲見真紀, 川邉明広, 平山尚志郎, 榎本豊, 北村俊雄, 濱崎純, 村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] 核UFD経路のE3リガーゼによるp53代謝制御機構の解明2023
- Author(s)
  柳川貴宏、平山尚志郎、西澤晏理、小迫英尊、村田茂穂
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ESCRT-I複合体は、小胞体上のコレステロール合成酵素のプロテアソーム分解に関与する2023
- Author(s)
  松井誠杜、門禹森、平山尚志郎、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] 哺乳類プロテアソームの新規転写因子の同定2023
- Author(s)
  橋本創太、王妍、董瑶加、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第96回生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] ESCRT-I複合体は、小胞体上のコレステロール合成酵素のプロテアソーム分解に関与する2023
- Author(s)
  松井誠杜、門禹森、平山尚志郎、小迫英尊、村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソームの機能制御因子の網羅的探索2023
- Author(s)
  稲見真紀, 川邉明広, 平山尚志郎, 榎本豊, 北村俊雄, 濱崎純, 村田茂穂
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K18107
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2023
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  第22回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PLANNED-23H04918
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソーム機能制御因子の網羅的探索2022
- Author(s)
  川邉明広, 濱崎純, 村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Role of senescence-associated nuclear proteasome foci2022
- Author(s)
  Shigeo Murata
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] DDI2過剰発現によるプロテアソーム活性亢進マウスにおけるタンパク質恒常性への影響の解析2022
- Author(s)
  加藤雅和、濱崎純、村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] The ESCRT-I complex mediates proteasomal degradation via PTPN232022
- Author(s)
  Shoshiro Hirayama, Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, and Shigeo Murata
- Organizer
  マルチモードオートファジー班会議
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ユビキチン様タンパク質FUBIがUFD基質の分解や細胞増殖に関与するメカニズムの解明2022
- Author(s)
  宗俊吾、藤原歩夢、平山尚志郎、村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 効率的なタンパク質合成にはリボソームタンパク質eS7がユビキチン化と脱ユビキチン化されることが重要である。2022
- Author(s)
  八代田英樹、竹原由香、松尾芳隆、Xian Zhao, 神垣あかね、松崎哲郎、小迫英尊、稲田利文、村田茂穂
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Analysis of the mechanism by which the ubiquitin-like protein FUBI regulates the degradation of ubiquitinated proteins and cell proliferation2022
- Author(s)
  Shungo Mune, Ayumu Fujiwara, Shoshiro Hirayama, Shigeo Murata
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] 効率的なタンパク質合成にはリボソームタンパク質eS7がユビキチン化と脱ユビキチン化されることが重要である。2022
- Author(s)
  八代田英樹、竹原由香、松尾芳隆、Xian Zhao, 神垣あかね、松崎哲郎、小迫英尊、稲田利文、村田茂穂
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Sorting of amyloidogenic tau repeat domain to the proteasome and microautophagy by ESCRT-I and PTPN-232022
- Author(s)
  Shoshiro Hirayama, Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, and Shigeo Murata
- Organizer
  The 10th International Symposium on Autophagy
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2022
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  Ubiquitin New Frontier International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] DDI2過剰発現によるプロテアソーム活性亢進マウスにおけるタンパク質恒常性への影響の解析2022
- Author(s)
  加藤雅和、濱崎純、村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Sorting of amyloidogenic tau repeat domain to the proteasome and microautophagy by ESCRT-I and PTPN-232022
- Author(s)
  Shoshiro Hirayama, Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, and Shigeo Murata
- Organizer
  The 10th International Symposium on Autophagy
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2022
- Author(s)
  Yusen Men, Shoshiro Hirayama, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, Shigeo Murata
- Organizer
  Ubiquitin New Frontier International Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] プロテアソーム活性を指標にしたCRISPRスクリーニングによる哺乳類プロテアソーム機能制御因子の網羅的探索2022
- Author(s)
  川邉明広, 濱崎純, 村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] The ESCRT-I complex mediates proteasomal degradation via PTPN232022
- Author(s)
  Shoshiro Hirayama, Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Megan Lo, and Shigeo Murata
- Organizer
  マルチモードオートファジー班会議
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] ユビキチン様タンパク質FUBIがUFD基質の分解や細胞増殖に関与するメカニズムの解明2022
- Author(s)
  宗俊吾、藤原歩夢、平山尚志郎、村田茂穂
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22H00402
[Presentation] ユビキチン・プロテアソーム系の不調による炎症性疾患発症の分子機構2022
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第5回日本免疫不全・自己炎症学会　総会・学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] ユビキチン・プロテアソーム系の不調による炎症性疾患発症の分子機構2022
- Author(s)
  濱崎純、村田茂穂
- Organizer
  第5回日本免疫不全・自己炎症学会　総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Analysis of the mechanism by which the ubiquitin-like protein FUBI regulates the degradation of ubiquitinated proteins and cell proliferation2022
- Author(s)
  Shungo Mune, Ayumu Fujiwara, Shoshiro Hirayama, Shigeo Murata
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] MHCクラスIの細胞膜表面における発現と抗原提示に関与する新規因子の探索2021
- Author(s)
  渡邊綾香、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 加齢依存的に凝集するタンパク質の同定とその生理的意義の解明2021
- Author(s)
  小湊樹、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 翻訳におけるリボソームタンパク質eS7のユビキチン化/脱ユビキチン化の重要性2021
- Author(s)
  八代田英樹、竹原由香、松尾芳隆、Xian Zhao、神垣あかね、松崎哲郎、小迫英尊、稲田利文、村田茂穂
- Organizer
  酵母遺伝学フォーラム　第５４回研究報告会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Screening of regulator of basal proteasome expression2021
- Author(s)
  Madoka Yamamura, Ryo Motosugi, Jun Hamazaki, Shigeo Murata
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] プロテアソーム転写因子Nrf1活性化に働く新規プロテアーゼDDI2によるプロセシング条件の検討2021
- Author(s)
  下岡雅和、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] プロテアソーム転写因子Nrf1活性化に働く新規プロテアーゼDDI2によるプロセシング条件の検討2021
- Author(s)
  下岡雅和、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] MHCクラスIの細胞膜表面における発現と抗原提示に関与する新規因子の探索2021
- Author(s)
  渡邊綾香、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 26Sプロテアソームの細胞内局在制御機構とその生理学的意義の解明2021
- Author(s)
  上羅彩加、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 加齢依存的に凝集するタンパク質の同定とその生理的意義の解明2021
- Author(s)
  小湊樹、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 哺乳類プロテアソームの基礎的発現制御因子の探索2021
- Author(s)
  山村まどか、本杉良、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Senescence-associated nuclear proteasome foci degrade p21 and suppress mitochondrial activation2021
- Author(s)
  増田竣, 入木朋洋, 安田柊, 小迫英尊, 平山尚志郎, 大竹史明, 佐伯泰, 濱崎純, 村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Screening of regulator of basal proteasome expression2021
- Author(s)
  Madoka Yamamura, Ryo Motosugi, Jun Hamazaki, Shigeo Murata
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 核のUFD経路の生理的意義の解明2021
- Author(s)
  西澤晏理、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] ユビキチンリガーゼRNF181はプロテアソーム機能低下時のプロテアソーム活性維持に重要な役割を果たす2021
- Author(s)
  吉敷純、平山尚志郎、小迫英尊、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 26Sプロテアソームの細胞内局在制御機構とその生理学的意義の解明2021
- Author(s)
  上羅彩加、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Elucidation of the mechanism of cleavage of transcription factor Nrf1 by DDI22021
- Author(s)
  Masakazu Shimooka, Jun Hamazaki, Shigeo Murata
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] ユビキチンリガーゼRNF181はプロテアソーム機能低下時のプロテアソーム活性維持に重要な役割を果たす2021
- Author(s)
  吉敷純、平山尚志郎、小迫英尊、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 哺乳類プロテアソームの基礎的発現制御因子の探索2021
- Author(s)
  山村まどか、本杉良、濱崎純、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Elucidation of the mechanism of cleavage of transcription factor Nrf1 by DDI22021
- Author(s)
  Masakazu Shimooka, Jun Hamazaki, Shigeo Murata
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 核のUFD経路の生理的意義の解明2021
- Author(s)
  西澤晏理、平山尚志郎、村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 翻訳におけるリボソームタンパク質eS7のユビキチン化/脱ユビキチン化の重要性2021
- Author(s)
  八代田英樹、竹原由香、松尾芳隆、Xian Zhao、神垣あかね、松崎哲郎、小迫英尊、稲田利文、村田茂穂
- Organizer
  酵母遺伝学フォーラム　第５４回研究報告会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Senescence-associated nuclear proteasome foci degrade p21 and suppress mitochondrial activation2021
- Author(s)
  増田竣, 入木朋洋, 安田柊, 小迫英尊, 平山尚志郎, 大竹史明, 佐伯泰, 濱崎純, 村田茂穂
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 細胞老化依存的に生じるプロテアソームfociの機能解析2020
- Author(s)
  安田柊、入木朋洋、増田竣、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity unde proteasome impairment.2020
- Author(s)
  Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] The ubiquitin ligase RNF181 plays a pivotal role in sustaining the mammalian proteasome activity unde proteasome impairment.2020
- Author(s)
  Shota Okuno, Eiichi Hashimoto, Shoshiro Hirayama, Hidetaka Kosako, Jun Hamazaki, and Shigeo Murata
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 細胞老化依存的に生じるプロテアソームfociの機能解析2020
- Author(s)
  安田柊、入木朋洋、増田竣、平山尚志郎、濱崎純、村田茂穂
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2020
- Author(s)
  Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Shoshiro Hirayama, Shigeo Murata
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Identification of factors modulating the clearance of aggregate-prone tau by genome-wide CRISPR screening2020
- Author(s)
  Yusen Men, Shinpei Ao, Yasuyuki Sakurai, Shoshiro Hirayama, Shigeo Murata
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] プロテアソームの機能制御と病態2019
- Author(s)
  村田茂穂
- Organizer
  第1回大阪骨関節コロキウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Identification of factors modulating the clearance of aggregated tau by genome-wide screening2019
- Author(s)
  青新平、櫻井靖之、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] How cells respond to proteasome impairment2019
- Author(s)
  Murata S
- Organizer
  Z-ZOMES Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 胸腺プロテアソームによるT細胞選択機構の発見とその病態生理機能解明2019
- Author(s)
  村田茂穂
- Organizer
  第92回日本生化学学会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] プロテアソームの機能制御と病態2019
- Author(s)
  村田茂穂
- Organizer
  第1回大阪骨関節コロキウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] ダイニン依存的新規アグリソーム形成機構の解明2019
- Author(s)
  安河内巧、伊藤隆裕、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 易凝集性タンパク質のユビキチン依存的細胞内局在制御機構2019
- Author(s)
  村田茂穂
- Organizer
  第14回臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] プロテアソームの機能制御と病態2019
- Author(s)
  村田茂穂
- Organizer
  Science Pioneers Consortium 2019
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] How cells respond to proteasome impairment2019
- Author(s)
  Murata S
- Organizer
  Z-ZOMES Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] ケモテクノロジーを利用したタンパク質分解制御2019
- Author(s)
  村田茂穂
- Organizer
  第1回新学術「ケモユビキチン」班会議・第2回ユビキチン研究会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] Identification of factors modulating the clearance of aggregated tau by genome-wide screening2019
- Author(s)
  青新平、櫻井靖之、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] How cells respond to proteasome impairment2019
- Author(s)
  Shigeo Murata
- Organizer
  X-ZOMES Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] How cells respond to proteasome impairment2019
- Author(s)
  Shigeo Murata
- Organizer
  X-ZOMES Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] ダイニン依存的新規アグリソーム形成機構の解明2019
- Author(s)
  安河内巧、伊藤隆裕、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 核および細胞質特異的なユビキチン依存性タンパク質分解機構の解明2019
- Author(s)
  藤原歩夢、横森一泉、青新平、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] How cells respond to proteasome impairment2019
- Author(s)
  Shigeo Murata
- Organizer
  X-ZOMES Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] プロテアソームの機能制御と病態2019
- Author(s)
  村田茂穂
- Organizer
  Science Pioneers Consortium 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] 易凝集性タンパク質のユビキチン依存的細胞内局在制御機構2019
- Author(s)
  村田茂穂
- Organizer
  第14回臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] 核および細胞質特異的なユビキチン依存性タンパク質分解機構の解明2019
- Author(s)
  藤原歩夢、横森一泉、青新平、平山尚志郎、村田茂穂
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] プロテアソーム機能低下時の細胞応答機構2018
- Author(s)
  村田茂穂
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Role of ubiquitination in nuclear export of proteins2018
- Author(s)
  村田茂穂
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Role of ubiquitination in nuclear export of proteins2018
- Author(s)
  村田茂穂
- Organizer
  第41回日本分子生物学会シンポジウム「ユビキチン研究の新潮流：ユビキチンコードを識る・操る」
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] A genome-wide siRNA screen reveals a new ubiquitin binding protein, which exports ubiquitinated proteins from the nucleus2018
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  International Symposium on "Proteins; from the Cradle to the Grave"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] Cell cycle -dependent or -independent regulation of subcellular localization of mammalian proteasomes2018
- Author(s)
  平山尚志郎、松浦昌太郎、村田茂穂
- Organizer
  X-ZOMES Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  8th workshop on proteasome and autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  8th workshop on proteasome and autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] タンパク質分解装置プロテアソームの機能制御機構と病態2018
- Author(s)
  村田茂穂
- Organizer
  愛媛大学TRCセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソーム機能調節介入による健康寿命の延長2018
- Author(s)
  村田茂穂
- Organizer
  AMED-CREST/PRIME機能低下・老化プロジェクト合同リトリート
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  The proteasome hub : fine tuning of proteolysis according to cellular needs
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  8th workshop on proteasome and autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] プロテアソーム機能低下時の細胞応答機構2018
- Author(s)
  村田茂穂
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Role of ubiquitination in nuclear export of proteins2018
- Author(s)
  村田茂穂
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  8th workshop on proteasome and autophagy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソームの分子多様性と生理機能の解明2018
- Author(s)
  村田茂穂
- Organizer
  2018年度持田記念学術賞講演
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソーム機能低下時の細胞応答機構2018
- Author(s)
  村田茂穂
- Organizer
  第91回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ケモテクノロジーを利用したタンパク質分解制御2018
- Author(s)
  村田茂穂
- Organizer
  新学術「ケモユビキチン」キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05500
[Presentation] A genome-wide siRNA screen reveals a new ubiquitin binding protein, which exports ubiquitinated proteins from the nucleus2018
- Author(s)
  平山尚志郎、伊藤隆裕、村田茂穂
- Organizer
  International Symposium on "Proteins; from the Cradle to the Grave"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] How cells respond to proteasome impairment2018
- Author(s)
  Shigeo Murata
- Organizer
  X-ZOMES Conference 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04022
[Presentation] A genome-wide siRNA screen reveals a new ubiquitin binding protein, which exports ubiquitinated proteins from the nucleus2018
- Author(s)
  Shigeo Murata
- Organizer
  International Symposium on “Proteins : from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソーム : 多彩な生命活動を支えるタンパク質分解装置のバイオロジー2017
- Author(s)
  村田茂穂
- Organizer
  高等研プロジェクト「生命活動を生体高分子への修飾から俯瞰する」
- Place of Presentation
  国際高等研究所(京都府木津川市)
- Year and Date
  2017-01-23
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Activation of Nrfl compensates for proteasome dysfunction2017
- Author(s)
  Shigeo Murata
- Organizer
  EMBO Conference “Protein quality control : success and failure in health and disease”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソーム：多彩な生命活動を支えるタンパク質分解装置のバイオロジー2017
- Author(s)
  村田　茂穂
- Organizer
  高等研プロジェクト「生命活動を生体高分子への修飾から俯瞰する」
- Place of Presentation
  国際高等研究所（京都府木津川市）
- Year and Date
  2017-01-23
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Regulation mechanisms of the proteasome2016
- Author(s)
  Shigeo Murata
- Organizer
  Ubiquitin international symposium "Diverse functions of Ubiquitin : Degradation, Signaling, and Beyond"
- Place of Presentation
  京都大学(京都府京都市)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソームの多様性と生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第32回高峰カンファレンス
- Place of Presentation
  如水会館（東京都千代田区）
- Year and Date
  2016-03-11
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111704
[Presentation] Regulation mechanism of proteasome activity2016
- Author(s)
  Shigeo Murata
- Organizer
  Ubiquitin Family, Autophagy and Disease. Cold Spring Harbor Asia Conference (CSH Asia)
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-04-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Regulation mechanisms of the proteasome2016
- Author(s)
  Shigeo Murata
- Organizer
  Ubiquitin international symposium "Diverse functions of Ubiquitin : Degradation, Signaling, and Beyond"
- Place of Presentation
  京都大学（京都府京都市）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Regulatory mechanism of the proteasome2016
- Author(s)
  Shigeo Murata
- Organizer
  Ubiquitin Family, Autophagy and Diseases Cold Spring Harbor Asia Conference (CSH Asia)
- Place of Presentation
  Suzhou, China
- Year and Date
  2016-04-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Identification of molecules involved in Nrf1 activation in response to proteasome inhibition2016
- Author(s)
  村田　茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Regulation mechanism of proteasome activity (Keynote lecture)2016
- Author(s)
  Shigeo Murata
- Organizer
  3rd proteostasis action meeting "Proteostasis and its Biological Implications"
- Place of Presentation
  Lisbon (Portugal)
- Year and Date
  2016-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] ブロテアソームの多様性と生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第32回高峰カンファレンス
- Place of Presentation
  如水会館(東京都千代田区)
- Year and Date
  2016-03-11
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Regulation mechanism of proteasome activity (Keynote lecture)2016
- Author(s)
  Shigeo Murata
- Organizer
  3rd proteostasis action meeting "Proteostasis and its Biological Implications"
- Place of Presentation
  Lisbon. Portugal
- Year and Date
  2016-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Identification of molecules involved in Nrf1 activation in response to proteasome inhibition2016
- Author(s)
  Shigeo Murata, Shun Koizumi, Jun Hamazaki
- Organizer
  FASEB SRC "Ubiquitin & Cellular Regulation"
- Place of Presentation
  Big Sky, Montana (USA)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] プロテアソームの多様性による生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第4回CAKIカンファレンス
- Place of Presentation
  リーガロイヤルホテル広島（広島県広島市）
- Year and Date
  2016-01-09
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] ブロテアソームの多様性による生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第4回CAKIカンファレンス
- Place of Presentation
  リーガロイヤルホテル広島(広島県広島市)
- Year and Date
  2016-01-09
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソームの多様性による生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第4回CAKIカンファレンス
- Place of Presentation
  リーガロイヤルホテル広島（広島県広島市）
- Year and Date
  2016-01-09
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111704
[Presentation] Regulation mechanism of proteasome activity2016
- Author(s)
  Shigeo Murata
- Organizer
  Cold Spring Harbor Asia Symposium "Ubiquitin Family. Autophagy, and Diseases"
- Place of Presentation
  Suzhou (China)
- Year and Date
  2016-04-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Identification of molecules involved in Nrf1 activation in response to proteasome inhibition2016
- Author(s)
  村田茂穂
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  バシフィコ横浜(神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソームの多様性と生体制御2016
- Author(s)
  村田茂穂
- Organizer
  第32回高峰カンファレンス
- Place of Presentation
  如水会館（東京都千代田区）
- Year and Date
  2016-03-11
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Identification of molecules involved in Nrfl activation in response to proteasome inhibition2016
- Author(s)
  Shigeo Murata, Shun Koizumi, Jun Hamazaki
- Organizer
  FASEB SRC "Ubiquitin & Cellular Regulation"
- Place of Presentation
  Big Sky, Montana, USA
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] 胸腺ブロテアソームによるT細胞正の選択の新しい機構2015
- Author(s)
  村田茂穂
- Organizer
  平成27年度日本生化学会関東支部例会
- Place of Presentation
  新潟日報メディアシップ(新潟県新潟市)
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] ブロテアソームの多様性と生体制御2015
- Author(s)
  村田茂穂
- Organizer
  第7回免疫適塾
- Place of Presentation
  スターツ総合研修センター(茨城県つくばみらい市)
- Year and Date
  2015-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] プロテアソームの多様性と生体制御2015
- Author(s)
  村田茂穂
- Organizer
  第7回免疫適塾
- Place of Presentation
  スターツ総合研修センター（茨城県つくばみらい市）
- Year and Date
  2015-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] 胸腺プロテアソームによるT細胞正の選択の新しい機構2015
- Author(s)
  村田茂穂
- Organizer
  平成27年度日本生化学会関東支部例会/第56回新潟生化学懇話会
- Place of Presentation
  新潟日報メディアシップ（新潟県新潟市）
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] プロテアソームの制御による生体調節2014
- Author(s)
  村田茂穂
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター、大阪府豊中市
- Year and Date
  2014-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] ミスフォールドタンパク質の細胞内動態制御機構2014
- Author(s)
  村田茂穂
- Organizer
  第9回臨床ストレス応答学会
- Place of Presentation
  岡山大学、岡山県岡山市
- Year and Date
  2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Thymoproteasome generates unique peptides that elicit positive selection of developing T cells2014
- Author(s)
  Shigeo Murata
- Organizer
  Cold Spring Harbor Asia Symposium "Protein Modification & Homeostasis"
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-06-17
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Rpn13 and Rpn10 coordinately play a role in degradation of ubiquitinated protein in mice2014
- Author(s)
  Shigeo Murata
- Organizer
  EMBO-CONICET ubiquitin conference 2014 "Ubiquitin & ubiquitin-like proteins : At the crossroads from chromatin to protein"
- Place of Presentation
  Buenos Aires, Argentina
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26000014
[Presentation] Presentation of unique peptide repertoire on MHC class I by the thymoproteasome2013
- Author(s)
  S. Murata
- Organizer
  The 5th IGAKUKEN international symposium on “Autophagy”
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] The mechanism for molecular assembly of the proteasome2013
- Author(s)
  S. Murata
- Organizer
  第86回日本生化学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Diversity of the proteasome2013
- Author(s)
  S. Murata
- Organizer
  The 35th Naito conference on “The ubiquitin-proteasome system: From basic mechanisms to pathophysiological roles
- Place of Presentation
  Sapporo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] The mechanism for molecular assembly of the proteasome2013
- Author(s)
  S. Murata
- Organizer
  54th international symposium on “ Biological Regulation and Enzyme Activity in Normal and Neoplastic Tissues
- Place of Presentation
  Bologna, Italy
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] The mechanism for molecular assembly of the proteasome2013
- Author(s)
  S. Murata
- Organizer
  54th international symposium on " Biological Regulation and Enzyme Activity in Normal and Neoplastic Tissues"
- Place of Presentation
  Bologna (Italy)
- Data Source
  KAKENHI-PROJECT-21000012
[Presentation] プロテアソームの制御メカニズム2013
- Author(s)
  村田茂穂
- Organizer
  第65回日本細胞生物学会年会
- Place of Presentation
  ウインク愛知（名古屋）
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Investigation of the biological meaning of ss subunit diversity2012
- Author(s)
  Akihiko Fukuda, Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23657083
[Presentation] Involvement of TRC/Get pathway in proteasome assembly2012
- Author(s)
  S. Murata
- Organizer
  FASEB summer research conference "Ubiquitin and cellular regulation"
- Place of Presentation
  Vermont (USA)
- Data Source
  KAKENHI-PROJECT-21000012
[Presentation] Enzymatic purification and mass spectrometric identification of polyubiquitinated proteins2012
- Author(s)
  Naoyuki Mita, Jun Hamazaki, Shigeo Murata
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23657083
[Presentation] プロテアソームとミトコンドリアの遺伝学的相互作用2011
- Author(s)
  白水亮平、八代田英樹、村田茂穂
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23657083
[Presentation] プロテアソームとミトコンドリアの遺伝学的相互作用2011
- Author(s)
  白水亮平、八代田英樹、村田茂穂
- Organizer
  第84回日本生化学会大会。
- Place of Presentation
  京都
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-23657083
[Presentation] The assemblypathway of the mammalian proteasome lid subcomplex PPDUP2010
- Author(s)
  金子岳海、村田茂穂
- Place of Presentation
  バンクーバー、カナダ
- Data Source
  KAKENHI-PROJECT-22790060
[Presentation] Proteasome diversity2010
- Author(s)
  S. Murata
- Organizer
  The Banbury symposium "Signaling through ubiquitin"
- Place of Presentation
  Cold Spring Harbor (USA)
- Data Source
  KAKENHI-PROJECT-21000012
[Presentation] シャペロン依存的プロテアソーム形成機構と病態2009
- Author(s)
  村田茂穂
- Organizer
  日本生化学会年会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] Production of positively selecting peptides by thymus- specific proteasomes.2009
- Author(s)
  Shigeo Murata
- Organizer
  The 2nd international symposium of WPI-IFReC
- Place of Presentation
  大阪
- Year and Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Production of positively selecting peptides by thymus-specific vroteasomes2009
- Author(s)
  Murata, S.
- Organizer
  The 2nd International Symposium of WPI-IFReC
- Place of Presentation
  吹田
- Year and Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] Proteasome assembly in mammals2009
- Author(s)
  Shigeo Murata
- Organizer
  EMBO Ubiquitin Meeting
- Place of Presentation
  イタリア
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Mechanism of proteasome assembly in mammalian cells2009
- Author(s)
  Shigeo Murata
- Organizer
  The 66th KSBMB Annual Meeting
- Place of Presentation
  ソウル、韓国
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Proteasome assembly in mammals2009
- Author(s)
  S. Murata
- Organizer
  EMBO conference on "Ubiquitin and ubiquitin-like modifiers in health and disease"
- Place of Presentation
  Riva del Garda (Italy)
- Data Source
  KAKENHI-PROJECT-21000012
[Presentation] シャペロン依存的プロテアソーム形成機構と病態。2009
- Author(s)
  村田茂穂
- Organizer
  日本生化学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] 胸腺特異的プロテアソームによるT細胞の選別。2009
- Author(s)
  村田茂穂
- Organizer
  第28回日本胸腺研究会
- Place of Presentation
  福岡
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] シャペロン依存的プロテアソーム形成機構と病態2009
- Author(s)
  村田茂穂
- Organizer
  日本生化学会年会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Proteasome assembly in mammals2009
- Author(s)
  村田茂穂
- Organizer
  Ubiquitin and ubiquitin-like modifiers in health and disease
- Place of Presentation
  IT-Riva del Garda Italia
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] 胸腺特異的プロテアソームによるT細胞の選別2009
- Author(s)
  村田茂穂
- Organizer
  第28回日本胸腺研究会
- Place of Presentation
  福岡
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] Proteasome assembly in mammals2009
- Author(s)
  村田茂穂
- Organizer
  Ubiquitin and ubiquitin-like modifiers in health and disease
- Place of Presentation
  IT-Riva del Garda Italia
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] プロテアソームの多様性による生命活動の制御とその分子基盤。2009
- Author(s)
  村田茂穂
- Organizer
  高遠シンポジウム
- Place of Presentation
  長野
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Dissecting the assembly pathway of the proteasome2009
- Author(s)
  村田茂穂
- Organizer
  The 32nd Annual Meeting of MBSJ
- Place of Presentation
  Yokohama
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] Production of positively selectingg peptides by thymus-specific proteasomes2009
- Author(s)
  Murata, S.
- Organizer
  The 2nd International Symposium of WPI-IFReC
- Place of Presentation
  吹田
- Year and Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Dissecting the assembly pathway of the proteasome2009
- Author(s)
  Shigeo Murata
- Organizer
  The 32nd Annual Meeting of MBSJ
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Mechanism of proteasome assembly in mammalian cells2009
- Author(s)
  村田茂穂
- Organizer
  The 66th KSBMB Annual Meeting
- Place of Presentation
  韓国ソウル
- Year and Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Mechanism of proteasome assembly in mammalian cells2009
- Author(s)
  村田茂穂
- Organizer
  The 66th KSBMB Annual Meeting
- Place of Presentation
  韓国ソウル
- Year and Date
  2009-05-12
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] 胸腺特異的プロテアソームによるT細胞の選別2009
- Author(s)
  村田茂穂
- Organizer
  第28回日本胸腺研究会
- Place of Presentation
  福岡
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームの多様性による生命活動の制御とその分子基盤2008
- Author(s)
  村田茂穂
- Organizer
  高遠シンポジウム
- Place of Presentation
  伊那
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームの形成機構と病態2008
- Author(s)
  村田茂穂
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Thymoproteasome regulate CD8+ T cell selection.2008
- Author(s)
  Shigeo Murata
- Organizer
  FASEB summer research conferences
- Place of Presentation
  アメリカ
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] 胸腺プロテアソームによる正の選択制御2008
- Author(s)
  村田茂穂
- Organizer
  第17回東京免疫フォーラム
- Place of Presentation
  東京
- Year and Date
  2008-03-11
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームの形成機構と病態2008
- Author(s)
  村田茂穂
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] プロテアソームの形成機構と病態。2008
- Author(s)
  村田茂穂
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Thymoproteasomes regulate CD8+ T cell selection2008
- Author(s)
  Murata, S.
- Organizer
  FASEB Summer Research conferences
- Place of Presentation
  Vermont, USA
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Thymoproteasomes regulate CD8+ T cell selection2008
- Author(s)
  Murata, S.
- Organizer
  FASEB Summer Research conferences
- Place of Presentation
  Vermont, USA
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] プロテアソームの多様性による生命活動の制御とその分子基盤2008
- Author(s)
  村田茂穂
- Organizer
  高遠シンポジウム
- Place of Presentation
  伊那
- Year and Date
  2008-08-22
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] Production of positively selecting peptides by thymus- specific proteasomes.2008
- Author(s)
  Shigeo Murata
- Organizer
  Takeda Symposium
- Place of Presentation
  東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Production of positively selectingg peptides by thymus-specific proteasomes2008
- Author(s)
  Murata, S.
- Organizer
  武田シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Production of positively selecting peptides by thymus-specific proteasomes2008
- Author(s)
  Murata, S.
- Organizer
  武田シンポジウム
- Place of Presentation
  シェラトン都ホテル東京
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20060036
[Presentation] プロテアソームによる生体制御2007
- Author(s)
  村田茂穂
- Organizer
  第2回臨床ストレス応答学会特別講演
- Place of Presentation
  福岡
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Regulation of positive selection of CD8 T cells by thymus-specific proteasomes2007
- Author(s)
  Shigeo Murata
- Organizer
  理化学研究所免疫アレルギー科学総合研究センター講演
- Place of Presentation
  横浜
- Year and Date
  2007-06-13
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Cooperation of multiple chaperones required for the assembly of mammalian 20S proteasomes2007
- Author(s)
  Shigeo Murata
- Organizer
  Koloquium in Universitatsmedizin Berlin
- Place of Presentation
  Berlin
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Thymoproteasomes regulate development of CD8+T cells in the thymus2007
- Author(s)
  Murata, S
- Organizer
  3rd Zeuthener see workshop 2007
- Place of Presentation
  Berlin(Germany)
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームによる適応免疫システム制御に関する研究2007
- Author(s)
  村田茂穂
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームの分子集合2007
- Author(s)
  村田茂穂
- Organizer
  第5回日本ヒトプロテオーム機構大会
- Place of Presentation
  東京
- Year and Date
  2007-07-30
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Regulation of positive selection of CD8 T cells by thymus-specific proteasomes2007
- Author(s)
  Shigeo Murata, et. al.
- Organizer
  第37回日本免疫学会総会Late Breaking symposium
- Place of Presentation
  東京
- Year and Date
  2007-11-02
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Regulation of positive selection of CD8 T cell by thymus-2007
- Author(s)
  Murata, S.
- Organizer
  第7回あわじしま感染症・免疫フォーラム
- Place of Presentation
  淡路島
- Year and Date
  2007-09-03
- Data Source
  KAKENHI-PROJECT-19044050
[Presentation] Molecular basis for the diversity of mammalian proteasomes2007
- Author(s)
  村田茂穂
- Organizer
  第59回日本細胞生物学会、第40回日本発生生物学会合同年会
- Place of Presentation
  福岡
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Regulation of positive selection of CD8 T cell by thymus-specific proteasowes2007
- Author(s)
  Murata, S.
- Organizer
  第7回あわじしま感染症・免疫フォーラム
- Place of Presentation
  淡路島
- Year and Date
  2007-09-03
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームによる生体制御2007
- Author(s)
  村田茂穂
- Organizer
  第2回臨床ストレス応答学会
- Place of Presentation
  福岡
- Year and Date
  2007-12-01
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Regulation of positive selection of CD8 T cell bythymus-specific proteanomes2007
- Author(s)
  村田茂穂
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] Regulation of positive selection of CD8 T cells by thymus-specific proteasomes2007
- Author(s)
  村田茂穂, 他
- Organizer
  BMB2007(第30回日本分子生物学会, 第80回日本生化学会合同年会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Molecular basis for the diversity of mammalian proteasomes2007
- Author(s)
  Murata, S
- Organizer
  第59回日本細胞生物学会
- Place of Presentation
  福岡
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] プロテアソームの多様性による生命活動の制御とその分子基盤2007
- Author(s)
  村田茂穂
- Organizer
  三菱生命研セミナー
- Place of Presentation
  東京
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] 胸腺特異的プロテアソームによるCD8+T細胞分化制御2007
- Author(s)
  村田茂穂, 他
- Organizer
  第17回KTCC
- Place of Presentation
  京都
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Regulation of positive selection of CDS T cell by thymusspecific proteanowes2007
- Author(s)
  Murata, S.
- Organizer
  日本免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19687009
[Presentation] 平成19年度日本生化学会奨励賞受賞講演「プロテアソームによる適応免疫システム制御に関する研究」2007
- Author(s)
  村田茂穂
- Organizer
  BMB2007(第30回日本分子生物学会, 第80回日本生化学会合同年会)
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Thymoproteasomes regulate development of CD8+T cells in the thymus2007
- Author(s)
  Murata, S
- Organizer
  3rd Zeuthener see workshop 2007
- Place of Presentation
  Berlin (Germany)
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-19044050
[Presentation] Regulation of positive selection of CD8 T cell by thymus-specific proteasomes2007
- Author(s)
  Shigeo Murata
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  Hyogo
- Year and Date
  2007-09-03
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] プロテアソームの多様性による生命活動の制御とその分子基盤2007
- Author(s)
  村田茂穂
- Organizer
  東京大学大学院薬学系研究科・生物系薬学セミナー
- Place of Presentation
  東京
- Year and Date
  2007-06-19
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] Thymoproteasomes regulate development of CD8+ T cells in the thymus2007
- Author(s)
  Shigeo Murata
- Organizer
  3rd Zeuthener See Workshop 2007
- Place of Presentation
  Berlin
- Year and Date
  2007-04-23
- Data Source
  KAKENHI-PROJECT-17002019
[Presentation] プロテアソームの制御による生体調節
- Author(s)
  村田茂穂
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（豊中市）
- Year and Date
  2014-08-08 – 2014-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] Rpn13 and Rpn10 coordinately play a role in degradation of ubiquitinated protein in mice
- Author(s)
  Shigeo Murata
- Organizer
  EMBO-CONICET ubiquitin conference 2014 "Ubiquitin & ubiquitin-like proteins: At the crossroads from chromatin to protein."
- Place of Presentation
  Buenos Aires. Argentina
- Year and Date
  2014-10-19 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] A heat shock proteins- and ubiquitin-interacting protein counteracts aggregate formation of ubiquitinated proteins for proteasome degradation
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, Erina Kuranaga, Masayuki Miura, and Shigeo Murata
- Organizer
  Symposium for young ubiquitin researchers in Japan "New Era in the Ubiquitin Research"
- Place of Presentation
  国際高等研究所 (木津川市)
- Year and Date
  2014-11-11 – 2014-11-12
- Data Source
  KAKENHI-PUBLICLY-26111704
[Presentation] プロテアソームの制御による生体調節
- Author(s)
  村田茂穂
- Organizer
  第19回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（豊中市）
- Year and Date
  2014-08-08 – 2014-08-09
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111704
[Presentation] ミスフォールドタンパク質の細胞内動態制御機構
- Author(s)
  村田茂穂
- Organizer
  第9回臨床ストレス応答学会
- Place of Presentation
  岡山大学（岡山市）
- Year and Date
  2014-11-01 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] A novel ubiquitin-interacting protein that counteracts aggregate formation of ubiquitinated proteins
- Author(s)
  Hiroyuki Uechi, Jun Hamazaki, Erina Kuranaga, Masayuki Miura, and Shigeo Murata
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都 (京都市)
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PUBLICLY-26111704
[Presentation] Thymoproteasome generates unique peptides that elicit positive selection of developing T cells
- Author(s)
  Shigeo Murata
- Organizer
  Cold Spring Harbor Asia Symposium "Protein Modification & Homeostasis"
- Place of Presentation
  Suzhou, China
- Year and Date
  2014-06-16 – 2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-25221102
[Presentation] ミスフォールドタンパク質の細胞内動態制御機構
- Author(s)
  村田茂穂
- Organizer
  第9回臨床ストレス応答学会
- Place of Presentation
  岡山大学（岡山市）
- Year and Date
  2014-11-01 – 2014-11-02
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111704
[]

1. KOMATSU Masaaki (90356254)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. TANAKA Keiji (10108871)

# of Collaborated Projects: 4 results

# of Collaborated Products: 67 results
3. 千葉智樹 (00311423)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. YASHIRODA Hideki (20311425)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. SAEKI Yasushi (80462779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 山野晃史 (30547526)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KANEKO Takeumi (80508135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. TAKAMURA Toshinari (00324111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. ISEKI Shoichi (50167251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. TANAHASHI nobuyuki (30511927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. YOSHIDA Yukiko (90271543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 上野隆 (10053373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 田中良和 (50291159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
14. 内藤幹彦 (00198011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 岩井一宏 (60252459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 深井周也 (10361792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 出水庸介 (90389180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡本晃充 (60314233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 石濱泰 (30439244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. LO MEGAN

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TAKADA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. OHIGASHI Izumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. MATSUDA Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. MORITO Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. ITO Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 濱崎純

# of Collaborated Projects: 0 results

# of Collaborated Products: 13 results
27. 高浜洋介

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
28. 松尾芳隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 廣田泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 駒田雅之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 長太のどか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 室龍之介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 金子周一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 石津明洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 外丸詩野

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 小迫英尊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 伊藤拓水

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 秋山泰身

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 安友康二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 永田和宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murata Shigeo 村田 茂穂

MURATA Shigeo 村田 茂穂

Research Projects

Research Products

Co-Researchers

Shin-biology regulated by protein lifetimeArea Organizer

Area Organizer

Project Period (FY)

Research Category

Shin-biology regulated by protein lifetimePrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

細胞・臓器老化におけるタンパク質寿命動態Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

プロテアソーム分解により機能を獲得するタンパク質およびペプチドの網羅的探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

凝集性タンパク質の新しい動態制御機構解明と病態連関の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

構造異常タンパク質の細胞内動態制御機構とその病態生理的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of protein degradation by chemo-technologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulatory mechanism of intracellular dynamics of conformationally aberrant proteins and its pathophysiological significancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ミスフォールドタンパク質の核外排出分子機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Screening for proteasome-activating compounds that could cure neurodegenerative diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Dynamics and function of the proteasomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Murata Shigeo 村田茂穂

MURATA Shigeo 村田茂穂