Kanai Takanori 金井隆典

… Alternative Names

KANAI Takanori 金井隆典

金井隆典カナイタカノリ

Less

Researcher Number	40245478
Other IDs
External Links
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 慶應義塾大学, 医学部(信濃町), 教授 2013 – 2015: 慶應義塾大学, 医学部, 教授 2013: 慶応義塾大学, 医学部, 教授 2008 – 2012: Keio University, 医学部, 准教授 2008: 慶應義塾大学, 内科, 准教授 … More 2003 – 2007: Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Assistant Professor, 医学部附属病院, 講師 2004: Tokyo Medical and Dental Univ., Dept.of Gastroenteorology and Hepatology, Assistant professor, 医学部・附属病院, 講師 2002: Tokyo Medical and Dental University, Department of Gastroenterology and Hepatology, Instructor, 医学部附属病院, 助手 2001: 東京医科歯科大学, 医学部・附属病院, 助手 1999: 慶應大, 医学部, 助手 1997 – 1998: 慶應義塾大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Medium-sized Section 53:Organ-based internal medicine and related fields / Biological Sciences / Gastroenterology Except Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences
Keywords	Principal Investigator 炎症性腸疾患 / 腸内細菌 / 潰瘍性大腸炎 / 原発性硬化性胆管炎 / 免疫学 / 自然免疫 / 制御性T細胞 / 下部消化管 / プロバイオティクス / 慢性大腸炎モデル … More / マウスモデル / 免疫記憶細胞 / IL-7 / 下部消化管学 / クローン病 / IgA / Th17細胞 / 腸管免疫 / メモリーT細胞 / 免疫学的加齢 / 新規治療法 / 慢性大腸炎 / 大腸炎 / メモリー細胞 / 粘膜免疫 / ノトバイオートマウス / 慢性免疫難病 / バクテリオファージ / Klebsiella pneumoniae / メタゲノム解析 / 腸管微小循環 / 腸内細菌叢 / AhRコンディショナルノックアウトマウス / 潰瘍性大腸炎（UC） / インジゴ類 / 青黛 / 腸管外合併症 / immunology / translational research / biological molecule / intestinal bacteria / マウス大腸炎モデル / トランスレーショナルリサーチ / 生体分子 / 細菌 / Transgenic mice / Cell transfer / Probiotics / Ulcerative colitis / Crohn's disease / Antigen-specific / murine model / inflammatory bowel diseases / 自己免疫疾患 / 単クローン / 腸管粘膜免疫 / 調節製T細胞 / 調節性T細胞 / トランスジェニックマウス / 細胞移入 / プロバイオテクス / 抗原特異性 / costimulation / chronic colitis / commensal bacteria / oral tolerance / mucosal immunity / therapy / inflammatory bowel disease / OX40 / マウス実験腸炎モデル / 乳酸菌 / costimulatory molecule / 腫瘍壊死因子 / 細胞療法 / 遺伝子導入 / Th1細胞 / 発酵学 / 先制医療 / IL-10 / マクロファージ / ディスバイオーシス / 末梢性トレランス / 抹消性トレランス / 免疫学的年齢 / プロバイオテ / 免疫統御 / Germ free / 無菌マウス / 免疫抑制 / 免疫学的記憶 / 永続性 / 難治性 / Interleukin-7 / 骨髄 / 免疫記憶T細胞 / 腸炎責任CD4 T細胞 / 免疫記憶T 細胞 / 腸炎責任CD4 T 細胞 / ミラクルビーズ / 内視鏡治療 / 大腸癌 / プラズマ / エフェクター細胞 / 抗原 / 老化 / CTL / 経口ワクチン / SIV / HIV / AIDS … More Except Principal Investigator 炎症性腸疾患 / IL-7 / 潰瘍性大腸炎 / 腸内細菌 / 慢性大腸炎 / 腸管上皮細胞 / 腸管免疫 / IL-7レセプター / 大腸癌 / 幹細胞 / マクロファージ / 再生医療 / 骨髄細胞 / 粘膜リンパ球 / IRF-2 / IRF-1 / intestinal epithelial cell / IL-7 receptor / 急性肝障害 / マウスモデル / 新規治療法 / 白血球除去療法 / Aryl Hydrocarbon受容体 / 青黛 / 腸内細菌叢 / 生薬青黛 / AhR リガンド / 肝線維化 / ケモカイン / Toll様受容体 / 免疫寛容 / 肝硬変 / 質量分析 / 遺伝性小腸潰瘍症 / CEAS / SLCO2A1 / プロスタグランジン / 小腸潰瘍 / 内視鏡 / leukocytapheresis / Crohn's disease / ulcerative colitis / inflammatory bowel disease / CD16 / TNFα / 単球・マクロファージ / 腸 / 末梢血 / 炎症性 / chronic colitis / transcriptional regulation / mucosal immunity / TSLP / IL-7受容体 / 粘膜内リンパ球 / Interferon Regulatory Factor / 遺伝子発現制御 / 腸管粘膜免疫制御 / Interferon Regulatory Factor-2 / Interferon Regulatory Factor-1 / 転写制御 / food allergy / chronic cohtis / bone marrow cell / regenerative medicine / mucosal jmmunity / 骨髄幹細胞 / 植物アレルギー / 食物アレルギー / 大腸がん / 下部消化管 / 下部消化管学 / alternative Th1 / 腸内細菌フローラ / probiotics / 拡大内視鏡 / リアルタイム / 迅速病理診断 / 超拡大内視鏡 / トランスレーショナルリサーチ / 免疫学 / ケモカイン受容体 / 肝臓学 / サイトカイン / NK細胞 / 抑制性T細胞 / 加齢化免疫記憶T細胞 / マウス大腸炎モデル / 腸炎惹起生免疫記憶T細胞 / 制御性T細胞 / 老化CD4+T細胞 / 加齢化免疫記憶CD4^+T細胞 / クローン病 / Wntシグナル / Notchシグナル / transdifferentiation / 分化誘導療法 / 画像情報 / 疾患診断システム / バイオマグネティックプローブ / リポソーム / ヘム / 生体内組織染色 / 磁性体 Less

Elucidation of the gut-liver-brain axis in response to host-invading bacteria and the development of treatments for gastrointestinal immune diseasesPrincipal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Pathogenesis of gastrointestinal immune intractable diseases via the intestinal immune response to host invading bacteria.Principal Investigator
- Principal Investigator
  
  Kanai Takanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
The elucidation of the World of AhR in the intestinal environment ,followed by the diverse clinical applications.Principal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 53:Organ-based internal medicine and related fields
- Research Institution
  Keio University
Investigation of the mechanisms for inhibitory effects on colonic inflammation and cancer of indigo naturalis including indole compounds
- Principal Investigator
  
  Naganuma Makoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of therapeutic strategy for identification of new markers for ulcerative colitis associated colorectal cancers.
- Principal Investigator
  
  Iwao Yasushi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of new vaccine therapy to promote the symbiotic bacteria in gut.Principal Investigator
- Principal Investigator
  
  Kanai Takanori
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
To identify the mechanism of inflammatory bowel disease by using human microbe mono-associated mousePrincipal Investigator
- Principal Investigator
  
  KANAI TAKANORI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Elucidation of the pathology and treatment of refractory small intestinal ulcer disease using genetically engineered mouse and PG mass spectrometry
- Principal Investigator
  
  HISAMATSU TADAKAZU
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyorin University
The interaction between the intestinal microbiota and hepatic macrophages in the pathogenesis of liver fibrosis
- Principal Investigator
  
  Nakamoto Nobuhiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Molecular characterization of Colitis Associated Cancer
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Identification of Symbiosis pattern decision factors and its reeducation programPrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Challenge to the cell therapy by reprogramming colitogenic memory T cellsPrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The microbiota in inflammatory bowel disease with resistance to anti-TNF therapy.
- Principal Investigator
  
  OKAZAWA Akira
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Research of Inflammatory Bowel Disease Based on Clinical Immunology and Endoscopy
- Principal Investigator
  
  IWAO Yasushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
自己類似腸内細菌フローラに対する免疫寛容とその破綻による炎症性腸疾患発症解明Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Pathogenesis of autoimmune hepatic injury through the migration of immunocompetent cells into the liver
- Principal Investigator
  
  NAKAMOTO Nobuhiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Challenging to the real-time in vivo diagnosis for inflammatory bowel disease by using super-magnifying endoscope.
- Principal Investigator
  
  OGATA Haruhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Investigation of intestinal macrophage in contribution to gut immune homeostasis and its disruption in Crohn's disease
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Permanent cure strategy of inflammatory bowel diseases by inducing immunological resetPrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
自己類似腸内細菌に対する末梢性免疫寛容の生体ライフスパンとその破綻Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Circulating colitogenic CD4+ memory T cells between bone marrow and intestine may be targets for the treatment of inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
  Tokyo Medical and Dental University
The development of regulatory T cell therapy using leukocyte apheresis for inflammatory bowel disease
- Principal Investigator
  
  NAGAHORI Masakazu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Immunosenescent colitogenic CD4^+ T cells convert to regulatory cells and suppress colitis
- Principal Investigator
  
  TOTUKA Teruji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
ミラクルビーズによる炎症性腸疾患責任抗原の同定と特異的免疫療法の開発Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
自己免疫疾患緩解増悪における免疫記憶細胞の役割とその免疫統御療法の開発Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
生体内で利用可能な超高周波低温プラズマを薬物担体として用いた内視鏡デバイスの開発Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
The establishment of bacteria antigen-specific T cell transgenic mice develop spontaneous chronic colitis, and the development of inhibitory probiotics for the treatment of inflammatory bowel diseasesPrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
The development of 2nd generated leukocytapheresis to remove phathological immune cells in inflammatory bowel diseases
- Principal Investigator
  
  ARAKI Akihiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
骨髄-腸上皮相互作用による腸管上皮幹細胞システム制御機構の解析
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Establishment of transgenic mice that recognize bacteria specific antigen and develop spontaneous colitis under specific pathogen free condition.Principal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
消化管粘膜免疫の特殊性を応用した腸管免疫機構の統御療法
- Principal Investigator
  
  渡辺守
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the regulatory mechanisms for mucosal immune response by mucosal IL-7/IL-7 receptor system
- Principal Investigator
  
  NAKAMURA Tetsuya
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
単クローン抗体を封入した病変部指向性磁性体による大腸疾患診断システムの開発
- Principal Investigator
  
  WATANABE Manabu
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the mechanism for regurating mucosal immune response and application for the treatment of chronic colitis and food allergy.
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Establishment of a novel therapy of Inflammatory bowel disease by inducible oral tolerancePrincipal Investigator
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
経口ワクチン開発のための腸管内HIV特異的細胞傷害性T細胞に関する基礎的研究Principal Investigator
- Principal Investigator
  
  金井隆典
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University

[Book] INTESTINE　大腸内視鏡（4）超拡大内視鏡2014
- Author(s)
  小林拓、長沼誠、緒方晴彦、日比紀文、金井隆典
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24249046
[Book] クローン病新しい診断と治療2011
- Author(s)
  日比紀文監修, 金井隆典編集
- Total Pages
  2018
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PUBLICLY-22021038
[Book] クローン病新しい診断と治療2011
- Author(s)
  日比紀文監修, 金井隆典編集
- Total Pages
  2018
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-21390233
[Book] 消化器BOOK炎症性腸疾患を日常診療で診る2011
- Author(s)
  金井隆典(分筆)
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21390233
[Book] クローン病新しい診断と治療2011
- Author(s)
  金井隆典, 他
- Total Pages
  2018
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-21390233
[Book] 消化器BOOK炎症性腸疾患を日常診療で診る2011
- Author(s)
  金井隆典(分筆)
- Publisher
  羊土社
- Data Source
  KAKENHI-PUBLICLY-22021038
[Book] Annual Review 消化器 2007.(中外医学社)2007
- Author(s)
  金井隆典, 渡辺守
- Publisher
  炎症性腸疾患からみた粘膜免疫のトピックス.
- Data Source
  KAKENHI-PROJECT-17047014
[Book] Annual Review 消化器 20072007
- Author(s)
  金井隆典, 渡辺守
- Total Pages
  264
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Book] Annual Review 消化器 20062006
- Author(s)
  金井隆典, 渡辺守
- Total Pages
  353
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Book] 外科2004
- Author(s)
  岡田英理子, 金井隆典, 渡辺守
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Bacteriophage therapy against pathological Klebsiella pneumoniae ameliorates the course of primary sclerosing cholangitis2023
- Author(s)
  Ichikawa Masataka、Nakamoto Nobuhiro、...、Kanai Takanori
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 3261-3261
- DOI
  10.1038/s41467-023-39029-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-23K27665
[Journal Article] Downregulation of chemokine receptor 9 facilitates CD4+CD8αα+ intraepithelial lymphocyte development2023
- Author(s)
  Ono Keiko、Sujino Tomohisa、Miyamoto Kentaro、Harada Yosuke、Kojo Satoshi、Yoshimatsu Yusuke、Tanemoto Shun、Koda Yuzo、Zheng Jiawen、Sayama Kazutoshi、Koide Tsuyoshi、...、Mucida Daniel、Taniuchi Ichiro、Kanai Takanori
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41467-023-40950-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K18213, KAKENHI-PROJECT-19KK0177, KAKENHI-PROJECT-21K07084, KAKENHI-PLANNED-19H05747, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K27590
[Journal Article] D-amino Acids Ameliorate Experimental Colitis and Cholangitis by Inhibiting Growth of Proteobacteria: Potential Therapeutic Role in Inflammatory Bowel Disease2023
- Author(s)
  Umeda Satoko、　Sujino Tomohisa、、、Shiomi Daisuke、Ashida Hiroshi、Kanai Takanori
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 16 Issue: 6 Pages: 1011-1031
- DOI
  10.1016/j.jcmgh.2023.08.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23K17415, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-21H02905, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27404, KAKENHI-PROJECT-23K27590
[Journal Article] The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis2023
- Author(s)
  Miyamoto Kentaro、Sujino Tomohisa、...、Kanai Takanori
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 113005-113005
- DOI
  10.1016/j.celrep.2023.113005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22H04995, KAKENHI-PROJECT-22H00465, KAKENHI-PROJECT-23H00425, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127, KAKENHI-PROJECT-23K27590
[Journal Article] Effectiveness and Durability of Ustekinumab Therapy With or Without Immunomodulators for Ulcerative Colitis Patients in Japan2022
- Author(s)
  Aoki Yasuhiro、Sujino Tomohisa、Kawaguchi Takaaki、Sugimoto Shinya、Shimada Fumie、Yoshimatsu Yusuke、Kiyohara Hiroki、Nanki Kosaku、Mikami Yohei、Takabayashi Kaoru、Hosoe Naoki、Ogata Haruhiko、Iwao Yasushi、Kanai Takanori
- Journal Title
  
  Crohn's & Colitis 360
  
  Volume: 4 Issue: 2 Pages: 1-10
- DOI
  10.1093/crocol/otac010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-21K19540
[Journal Article] Organ and brain crosstalk: The liver-brain axis in gastrointestinal, liver, and pancreatic diseases2022
- Author(s)
  Matsubara Yuta、Kiyohara Hiroki、Teratani Toshiaki、Mikami Yohei、Kanai Takanori
- Journal Title
  
  Neuropharmacology
  
  Volume: 205 Pages: 108915-108915
- DOI
  10.1016/j.neuropharm.2021.108915
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05123, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-21H02906
[Journal Article] Significance of 5-Aminosalicylic Acid Intolerance in the Clinical Management of Ulcerative Colitis2022
- Author(s)
  Mikami Yohei、Tsunoda Junya、Suzuki Shohei、Mizushima Ichiro、Kiyohara Hiroki、Kanai Takanori
- Journal Title
  
  Digestion
  
  Volume: 104 Issue: 1 Pages: 58-65
- DOI
  10.1159/000527452
- Data Source
  KAKENHI-PROJECT-20H00536
[Journal Article] Enrichment of type I interferon signaling in colonic group 2 innate lymphoid cells in experimental colitis2022
- Author(s)
  Irie Emi、Ishihara Rino、Mizushima Ichiro、Hatai Shunya、Hagihara Yuya、Takada Yoshiaki、Tsunoda Junya、Iwata Kentaro、Matsubara Yuta、Yoshimatsu Yusuke、Kiyohara Hiroki、Taniki Nobuhito、Sujino Tomohisa、Takabayashi Kaoru、Hosoe Naoki、Ogata Haruhiko、Teratani Toshiaki、Nakamoto Nobuhiro、Mikami Yohei、Kanai Takanori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 01-10
- DOI
  10.3389/fimmu.2022.982827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07994, KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05123, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03666, KAKENHI-PROJECT-21H02906, KAKENHI-PROJECT-21J12194
[Journal Article] Heterogeneity of ILC2s in the Intestine; Homeostasis and Pathology2022
- Author(s)
  Sunaga Shogo、Tsunoda Junya、Teratani Toshiaki、Mikami Yohei、Kanai Takanori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.867351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05120, KAKENHI-PLANNED-21H05123, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03666
[Journal Article] Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut2022
- Author(s)
  Yoshimatsu Yusuke、Sujino Tomohisa、Hosoe Naoki、et al.
- Journal Title
  
  Cell Reports
  
  Volume: 39 Issue: 6 Pages: 110773-110773
- DOI
  10.1016/j.celrep.2022.110773
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07994, KAKENHI-PROJECT-21K18272, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-21H02905
[Journal Article] An organoid-based organ-repurposing approach to treat short bowel syndrome2021
- Author(s)
  Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, Ishikawa K, Miyamoto K, Toshimitsu K, Takahashi S, Nanki K, Hakamata Y, Kanai T, Sato T.
- Journal Title
  
  Nature
  
  Volume: 592 Pages: 99-104
- DOI
  10.1038/s41586-021-03247-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-23K20316
[Journal Article] Circadian rhythms in the tissue-specificity from metabolism to immunity: insights from omics studies2021
- Author(s)
  Kinouchi Kenichiro、Mikami Yohei、Kanai Takanori、Itoh Hiroshi
- Journal Title
  
  Molecular Aspects of Medicine
  
  Volume: 80 Pages: 100984-100984
- DOI
  10.1016/j.mam.2021.100984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09012, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03666, KAKENHI-PROJECT-21K18270
[Journal Article] Phase 1 study on the safety and efficacy of E6011, antifractalkine antibody, in patients with Crohn's disease.2021
- Author(s)
  Matsuoka K., Naganuma M., Hibi T., Tsubouchi H., Oketani K., Katsurabara T., Hojo S., Takenaka O., Kawano T., Imai T., Kanai T.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Issue: 8 Pages: 2180-2186
- DOI
  10.1111/jgh.15463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Characteristics of the Mucosal Surface on Scanning Electron Microscopy in Patients with Remitting Ulcerative Colitis2021
- Author(s)
  Nomura E, Sujino T, Hosoe N, Yoshimatsu Y, Tanemoto S, Takabayashi K, Mutaguchi M, Shimoda M, Naganuma M, Ogata H, Kanai T.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: - Issue: 9 Pages: 1-6
- DOI
  10.1007/s10620-020-06609-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19K16592, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-20H03665
[Journal Article] Pulmonary Arterial Hypertension Caused by AhR Signal Activation Protecting against Colitis.2021
- Author(s)
  Hiraide T., Teratani T., Uemura S., Yoshimatsu Y., Naganuma M., Shinya Y., Momoi M., Kobayashi E., Hakamata Y., Fukuda K., Kanai T., Kataoka M.
- Journal Title
  
  Am J Respir Crit Care Med
  
  Volume: 203 Issue: 3 Pages: 385-388
- DOI
  10.1164/rccm.202009-3385le
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18K08154
[Journal Article] Underwater endoscopic mucosal resection for a sporadic adenoma located at severe longitudinal ulcer scars in ulcerative colitis.2021
- Author(s)
  Takabayashi K, Kato M, Sasaki M, Iwao Y, Ogata H, Kanai T, Yahagi N.
- Journal Title
  
  Endoscopy
  
  Volume: - Issue: 01 Pages: E30-E31
- DOI
  10.1055/a-1368-3796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16592, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-21H02905
[Journal Article] Bacteriotherapy for inflammatory bowel disease2021
- Author(s)
  Yusuke Yoshimatsu, Yohei Mikami, Takanori Kanai
- Journal Title
  
  Inflammation Regeneration
  
  Volume: 41 Issue: 1 Pages: 3-3
- DOI
  10.1186/s41232-020-00153-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-20H03666
[Journal Article] Adrenomedullin for steroid-resistant ulcerative colitis: a randomized, double-blind, placebo-controlled phase-2a clinical trial.2021
- Author(s)
  Kita T, Ashizuka S, Ohmiya N, Yamamoto T, Kanai T, Motoya S, Hirai F, Nakase H, Moriyama T, Nakamura M, Suzuki Y, Kanmura S, Kobayashi T, Ohi H, Nozaki R, Mitsuyama K, Yamamoto S, Inatsu H, Watanabe K, Hibi T, Kitamura K.
- Journal Title
  
  J Gastroenterol
  
  Volume: 56 Issue: 2 Pages: 147-157
- DOI
  10.1007/s00535-020-01741-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18H02810, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-19K08481
[Journal Article] Pathogenesis and management of gastrointestinal inflammation and fibrosis: from inflammatory bowel diseases to endoscopic surgery2021
- Author(s)
  Iwata Kentaro、Mikami Yohei、Kato Motohiko、Yahagi Naohisa、Kanai Takanori
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 41 Issue: 1
- DOI
  10.1186/s41232-021-00174-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-20H03666
[Journal Article] Effects of vedolizumab in Japanese patients with Crohn's disease: a prospective, multicenter, randomized, placebo-controlled Phase 3 trial with exploratory analyses.2020
- Author(s)
  Watanabe K, Motoya S, Ogata H, Kanai T, Matsui T, Suzuki Y, Shikamura M, Sugiura K, Oda K, Hori T, Araki T, Watanabe M, Hibi T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 3 Issue: 3 Pages: 291-306
- DOI
  10.1007/s00535-019-01647-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma.2020
- Author(s)
  Kawasaki K, Fujii M, Sugimoto S, Ishikawa K, Matano M, Ohta Y, Toshimitsu K, Takahashi S, Hosoe N, Sekine S, Kanai T, Sato T.
- Journal Title
  
  Gastroenterology
  
  Volume: 3 Issue: 3 Pages: 638-651
- DOI
  10.1053/j.gastro.2019.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-17J04827, KAKENHI-PROJECT-18J21346
[Journal Article] Significance of endoscopic deep small bowel evaluation using balloon-assisted enteroscopy for Crohn’s disease in clinical remission2020
- Author(s)
  Takabayashi Kaoru、Hosoe Naoki、Kato Motohiko、Hayashi Yukie、Nanki Kosaku、Fukuhara Kayoko、Mikami Yohei、Mizuno Shinta、Sujino Tomohisa、Mutaguchi Makoto、Naganuma Makoto、Yahagi Naohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 1 Pages: 25-33
- DOI
  10.1007/s00535-020-01737-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246
[Journal Article] Angiopoietin-like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells.2020
- Author(s)
  Teratani T., Tomita K., Wada A., Sugihara N., Higashiyama M., Inaba K., Horiuchi K., Hanawa Y., Nishii S., Mizoguchi A., Tanemoto R., Ito S., Okada Y., Kurihara C., Akita Y., Narimatsu K., Watanabe C., Komoto S., Oike Y., Miura S., Hokari R., Kanai T.
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 5 Pages: 580-592
- DOI
  10.1111/hepr.13603
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-21H02906, KAKENHI-PROJECT-18K07924
[Journal Article] Development of a scalable co-culture system for gut anaerobes and human colon epithelium2020
- Author(s)
  Sasaki Nobuo、Miyamoto Kentaro、Maslowski Kendle M.、Ohno Hiroshi、Kanai Takanori、Sato Toshiro
- Journal Title
  
  Gastroenterology
  
  Volume: in Press Issue: 1 Pages: 388-390
- DOI
  10.1053/j.gastro.2020.03.021
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-19K22544, KAKENHI-PROJECT-18KK0246
[Journal Article] Mucosal concentrations of N-acetyl-5-aminosalicylic acid is related to endoscopic activity in ulcerative colitis patients with mesalamine.2020
- Author(s)
  Fukuda T, Naganuma M, Takabayashi K, Hagihara Y, Tanemoto S, Nomura E, Yoshimatsu Y, Sugimoto S, Nanki K, Mizuno S, Mikami Y, Fukuhara K, Sujino T, Mutaguchi M, Inoue N, Ogata H, Iwao Y, Abe T, Kanai T.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 35 Issue: 11 Pages: 1878-1885
- DOI
  10.1111/jgh.15059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08381, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03746, KAKENHI-PROJECT-18KK0246
[Journal Article] Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study.2020
- Author(s)
  Naganuma M, Sugimoto S, Fukuda T, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka K, Hisamatsu T, Watanabe K, Mizuno S, Abe T, Suzuki Y, Kanai T; INDIGO Study Group.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 55 Issue: 2 Pages: 169-180
- DOI
  10.1007/s00535-019-01625-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18H03172
[Journal Article] Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter randomised controlled trial.2020
- Author(s)
  Naganuma M, Yokoyama Y, Motoya S, Watanabe K, Sawada K, Hirai F, Yamamoto T, Hanai H, Omori T, Kanai T, Hibi T
- Journal Title
  
  J Gastroenterol
  
  Volume: 4 Issue: 4 Pages: 390-400
- DOI
  10.1007/s00535-019-01651-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Somatic inflammatory gene mutations in human ulcerative colitis epithelium.2020
- Author(s)
  Nanki K, Fujii M, Shimokawa M, Matano M, Nishikori S, Date S, Takano A, Toshimitsu K, Ohta Y, Takahashi S, Sugimoto S, Ishimaru K, Kawasaki K, Nagai Y, Ishii R, Yoshida K, Sasaki N, Hibi T, Ishihara S, Kanai T, Sato T.
- Journal Title
  
  Nature
  
  Volume: 7789 Issue: 7789 Pages: 254-259
- DOI
  10.1038/s41586-019-1844-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-17J04827, KAKENHI-PROJECT-18J21346, KAKENHI-PROJECT-17K09395, KAKENHI-PROJECT-19H03455, KAKENHI-PROJECT-19K22544
[Journal Article] The liver-brain-gut neural arc maintains the Treg cell niche in the gut2020
- Author(s)
  Teratani T, Mikami Y, Nakamoto N, Suzuki T, Harada Y, Okabayashi K, Hagihara Y, Taniki N, Kohno K, Sibata S, Miyamoto K, Ishigame H, Chu Po-Sung, Sujino T, Suda W, Hattori M, Matsui M, Okada T, Okano H, Inoue M, Yada T, Kitagawa Y, Yoshimura A, Tanida M, Tsuda M, Iwasaki Y, Kanai T.
- Journal Title
  
  Nature
  
  Volume: 585 Issue: 7826 Pages: 591-596
- DOI
  10.1038/s41586-020-2425-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22611, KAKENHI-PROJECT-20K17062, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-17H06175, KAKENHI-PROJECT-19H05658, KAKENHI-PROJECT-20H00536, KAKENHI-PROJECT-19H04045, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-20H03666, KAKENHI-PROJECT-20H04133, KAKENHI-PROJECT-20K20384, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18K14840, KAKENHI-PROJECT-18KK0246
[Journal Article] Factors contributing to the systemic clearance of infliximab with long-term administration in Japanese patients with Crohn’s disease: Analysis using population pharmacokinetics2020
- Author(s)
  Matsuoka Katsuyoshi、Hamada Shunsuke、Shimizu Mikiko、Nanki Kosaku、Mizuno Shinta、Kiyohara Hiroki、Arai Mari、Sugimoto Shinya、Iwao Yasushi、Ogata Haruhiko、Hisamatsu Tadakazu、Nagauma Makoto、Kanai Takanori、Mochizuki Mayumi、Hashiguchi Masayuki
- Journal Title
  
  Int. Journal of Clinical Pharmacology and Therapeutics
  
  Volume: 58 Issue: 02 Pages: 89-102
- DOI
  10.5414/cp203569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05914, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-15K08045
[Journal Article] Relationship between osteoporosis, sarcopenia, vertebral fracture, and osteosarcopenia in patients with primary biliary cholangitis2020
- Author(s)
  Saeki Chisato、Oikawa Tsunekazu、Kanai Tomoya、Nakano Masanori、Torisu Yuichi、Sasaki Nobuyuki、Abo Masahiro、Saruta Masayuki、Tsubota Akihito
- Journal Title
  
  European Journal of Gastroenterology & Hepatology
  
  Volume: 33 Issue: 5 Pages: 731-737
- DOI
  10.1097/meg.0000000000001791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08937, KAKENHI-PROJECT-18KK0246
[Journal Article] Redox-dependent PPARγ/Tnpo1 complex formation enhances PPARγ nuclear localization and signaling2020
- Author(s)
  Teratani Toshiaki、Tomita Kengo、Toma-Fukai Sachiko、Nakamura Yutaro、Itoh Toshimasa、Shimizu Hikaru、Shiraishi Yasunaga、Sugihara Nao、Higashiyama Masaaki、Shimizu Takahiko、Inoue Ikuo、Takenaka Yasuhiro、Hokari Ryota、Adachi Takeshi、Shimizu Toshiyuki、Miura Soichiro、Kanai Takanori
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 156 Pages: 45-56
- DOI
  10.1016/j.freeradbiomed.2020.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17204, KAKENHI-PROJECT-18H02815, KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18K07924
[Journal Article] Long‐term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine2019
- Author(s)
  Akiyama Shintaro、Takenaka Kento、et al
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 10 Pages: 1751-1757
- DOI
  10.1111/jgh.14693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07902, KAKENHI-PROJECT-19K05914, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-15K08045, KAKENHI-PROJECT-17K09370
[Journal Article] How Can We Assess "Complete Healing" Beyond Endoscopic Remission?2019
- Author(s)
  Fukuda T, Naganuma M, Kanai T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 25 Issue: 6 Pages: e68-e68
- DOI
  10.1093/ibd/izy356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Idiopathic Thrombocytopenic Purpura Responsive to Surgery for Crohn's Disease2019
- Author(s)
  Mizuno S, Naganuma M, Kanai T
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 25 Issue: 3 Pages: e26-e26
- DOI
  10.1093/ibd/izy233
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Withdrawal of thiopurines in Crohn’s disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2)2019
- Author(s)
  Hisamatsu Tadakazu、DIAMOND2 Study Group、Kato Shingo、Kunisaki Reiko、Matsuura Minoru、Nagahori Masakazu、Motoya Satoshi、Esaki Motohiro、Fukata Norimasa、Inoue Satoko、Sugaya Takeshi、Sakuraba Hirotake、Hirai Fumihito、Watanabe Kenji、Kanai Takanori、Naganuma Makoto、Nakase Hiroshi、et al.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Issue: 10 Pages: 860-870
- DOI
  10.1007/s00535-019-01582-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18KK0246
[Journal Article] Epigenetic regulation of T helper cells and intestinal pathogenicity2019
- Author(s)
  Hagihara Yuya、Yoshimatsu Yusuke、Mikami Yohei、Takada Yoshiaki、Mizuno Shinta、Kanai Takanori
- Journal Title
  
  Seminars in Immunopathology
  
  Volume: - Issue: 3 Pages: 379-399
- DOI
  10.1007/s00281-019-00732-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15966, KAKENHI-PROJECT-18KK0246
[Journal Article] Development of an Indigo Naturalis Suppository for Topical Induction Therapy in Patients with Ulcerative Colitis2019
- Author(s)
  Yoshimatsu Yusuke、Naganuma Makoto、Sugimoto Shinya、Tanemoto Shun、Umeda Satoko、Fukuda Tomohiro、Nomura Ena、Yoshida Kosuke、Ono Keiko、Mutaguchi Makoto、Nanki Kosaku、Mizuno Shinta、Mikami Yohei、Fukuhara Kayoko、Sujino Tomohisa、Takabayashi Kaoru、Ogata Haruhiko、Iwao Yasushi、Kanai Takanori
- Journal Title
  
  Digestion
  
  Volume: 1 Issue: 4 Pages: 1-7
- DOI
  10.1159/000501152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-17H05082
[Journal Article] Adverse events in patients with ulcerative colitis treated with indigo naturalis: a Japanese nationwide survey2019
- Author(s)
  Naganuma M, Sugioto S, Suzuki H, Matsuno Y, Araki T, Shimizu H, Hayashi R, Fukuda T, Nakamoto N, Iijima H, Nakamura S, Kataoka M, Tamura Y, Tatsumi K, Hibi T, Suzuki Y, Kani T, INDIGO survey Group
- Journal Title
  
  J Gastroenterol
  
  Volume: 54(10) Issue: 10 Pages: 891-896
- DOI
  10.1007/s00535-019-01591-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08183, KAKENHI-PROJECT-18KK0246
[Journal Article] Current new challenges in the management of ulcerative colitis.2019
- Author(s)
  Fukuda T, Naganuma M, Kanai T.
- Journal Title
  
  Intest Res
  
  Volume: 17 Issue: 1 Pages: 36-44
- DOI
  10.5217/ir.2018.00126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Intramucosal poorly differentiated and signet-ring cell components in patients with ulcerative colitis-associated high-grade dysplasia.2019
- Author(s)
  Sugimoto S, Shimoda M, Iwao Y, Mutaguchi M, Nanki K, Mizuno S, Kameyama K, Ogata H, Naganuma M, Kanai T.
- Journal Title
  
  Dig Endosc
  
  Volume: 6 Issue: 6 Pages: 706-711
- DOI
  10.1111/den.13482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] he Relationship between Gut Microbiome, Immune System, and Cancer2019
- Author(s)
  Ichikawa M, Sujino T, Kanai T
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 46 Pages: 1807-1813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Concerns and side effects of azathioprine during adalimumab induction and maintenance therapy for Japanese patients with Crohn's disease: a sub-analysis of a prospective randomized clinical trial (DIAMOND study).2019
- Author(s)
  Hisamatsu T, Matsumoto T, Watanabe K,;Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 印刷中 Issue: 9 Pages: 1097-1104
- DOI
  10.1093/ecco-jcc/jjz030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18H02799
[Journal Article] Middle-term prognosis in patients with ulcerative colitis who achieved clinical and endoscopic remission by budesonide rectal foam.2019
- Author(s)
  Naganuma M, Hirai F, Kobayashi K, Watanabe K, Takeuchi K, Aoyama N, Nozawa H, Motoya S, Ohmori T, Harada A, Nagai Y, Abe T, Yamada Y, Inagaki K, Shimizu N, Kanai T, Watanabe M.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 8 Pages: e0220413-e0220413
- DOI
  10.1371/journal.pone.0220413
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Efficacy of Therapeutic Intervention for Patients With an Ulcerati Colitis Mayo Endoscopic Score of 12019
- Author(s)
  Fukuda T, Naganuma M, Sugimoto S, Ono K, Nanki K, Mizuno S, Kimura K, Mutaguchi M, Nakazato Y, Takabayashi K, Inoue N, Ogata H, Iwao Y, Kanai T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 25 Issue: 4 Pages: 782-788
- DOI
  10.1093/ibd/izy300
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246
[Journal Article] Difference in the clinical characteristic and prognosis of colitis-associated cancer and sporadic neoplasia in ulcerative colitis patients2019
- Author(s)
  Mutaguchi Makoto、Naganuma Makoto、Sugimoto Shinya、Fukuda Tomohiro、Nanki Kosaku、Mizuno Shinta、Hosoe Naoki、Shimoda Masayuki、Ogata Haruhiko、Iwao Yasushi、Kanai Takanori
- Journal Title
  
  Digestive and Liver Disease
  
  Volume: 51 Issue: 9 Pages: 1257-1264
- DOI
  10.1016/j.dld.2019.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-18KK0246
[Journal Article] Significance of Conducting 2 Types of Fecal Tests in Patients with Ulcerative Colitis.2019
- Author(s)
  Naganuma M, Kobayashi T, Nasuno M, Motoya S, Kato S, Matsuoka K, Hokari R, Watanabe C, Sakamoto H, Yamamoto H, Sasaki M, Watanabe K, Iijima H, Endo Y, Ichikawa H, Ozeki K, Tanida S, Ueno N, Fujiya M, Sako M, Takeuchi K, Sugimoto S, Abe T, Hibi T, Suzuki Y, Kanai T.
- Journal Title
  
  Clin Gastroenterol Hepatol
  
  Volume: 19 Issue: 5 Pages: 30843-2
- DOI
  10.1016/j.cgh.2019.07.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-19K08381
[Journal Article] Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn's Disease: A Propensity Score-Matched Study2019
- Author(s)
  Takabayashi Kaoru、Hosoe Naoki、Kato Motohiko、Hayashi Yukie、Miyanaga Ryoichi、Nanki Kosaku、Fukuhara Kayoko、Mikami Yohei、Mizuno Shinta、Sujino Tomohisa、Mutaguchi Makoto、Naganuma Makoto、Yahagi Naohisa、Ogata Haruhiko、Kanai Takanori
- Journal Title
  
  Gut and Liver
  
  Volume: - Issue: 5 Pages: 1-6
- DOI
  10.5009/gnl19228
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08402, KAKENHI-PROJECT-19K22624, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-20H03665, KAKENHI-PROJECT-18KK0246
[Journal Article] Reconstruction of the Human Colon Epithelium In Vivo.2018
- Author(s)
  Sugimoto S, Ohta Y, Fujii M, Matano M, Shimokawa M, Nanki K, Date S, Nishikori S, Nakazato Y, Nakamura T, Kanai T, Sato T.
- Journal Title
  
  Cell Stem Cell.
  
  Volume: 22 Issue: 2 Pages: 171-176
- DOI
  10.1016/j.stem.2017.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K19674, KAKENHI-PROJECT-17K15967, KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827
[Journal Article] Toll-Like Receptor 7 Agonist-Induced Dermatitis Causes Severe Dextran Sulfate Sodium Colitis by Altering the Gut Microbiome and Immune Cells.2018
- Author(s)
  Kiyohara H, Sujino T, Teratani T, Miyamoto K, Arai MM, Nomura E, Harada Y, Aoki R, Koda Y, Mikami Y, Mizuno S, Naganuma M, Hisamatsu T, Kanai T.
- Journal Title
  
  Cell Mol Gastroenterol Hepatol.
  
  Volume: 7 Issue: 1 Pages: 135-156
- DOI
  10.1016/j.jcmgh.2018.09.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08014, KAKENHI-PROJECT-17H05082, KAKENHI-PROJECT-17K19668, KAKENHI-PROJECT-17K15966, KAKENHI-PROJECT-18KK0246
[Journal Article] Single fecal microbiota transplantation failed to change intestinal microbiota and had limited effectiveness against ulcerative colitis in Japanese patients2017
- Author(s)
  Mizuno S, Nanki K, Matsuoka K, Saigusa K, Ono K, Arai M, Sugimoto S, Kiyohara H, Nakashima M, Takeshita K, Naganuma M, Suda W, Hattori M, Kanai T.
- Journal Title
  
  Intest Res
  
  Volume: 15(1) Issue: 1 Pages: 68-74
- DOI
  10.5217/ir.2017.15.1.68
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K15298
[Journal Article] Visualization and Targeting of LGR5+ Human Colon Cancer Stem Cells2017
- Author(s)
  Shimokawa M, Ohta Y, Nishikori S, Matano M, Takano A, Fujii M, Date S, Sugimoto S, Kanai T, Sato T
- Journal Title
  
  Nature
  
  Volume: 印刷中 Issue: 7653 Pages: 13-14
- DOI
  10.1038/nature22081
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J06065, KAKENHI-PROJECT-15K15297, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15K19349, KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-16K09325, KAKENHI-PROJECT-17K09395, KAKENHI-ORGANIZER-26115001, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-17J04827
[Journal Article] Endocytoscopy can be used to assess histological healing in ulcerative colitis patients with clinical and endoscopic remission2017
- Author(s)
  Yoshihiro Nakazato, Makoto Naganuma, Shinya Sugimoto, Rieko Bessho, Mari Arai, Hiroki Kiyohara, Keiko Ono, Kosaku Nanki, Makoto Mutaguchi, Shinta Mizuno, Taku Kobayashi, Naoki Hosoe, Masayuki Shimoda, Takayuki Abe, Nagamu Inoue, Haruhiko Ogata, Yasushi Iwao, Takanori Kanai
- Journal Title
  
  Endoscopy
  
  Volume: 49 Issue: 06 Pages: 560-563
- DOI
  10.1055/s-0043-106556
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K08564, KAKENHI-PROJECT-15K08974
[Journal Article] Free cholesterol accumulation in liver sinusoidal endothelial cells exacerbates acetaminophen hepatotoxicity via TLR9 signaling2017
- Author(s)
  Teratani Toshiaki、Tomita Kengo、Suzuki Takahiro、Furuhashi Hirotaka、Irie Rie、Hida Shigeaki、Okada Yoshikiyo、Kurihara Chie、Ebinuma Hirotoshi、Nakamoto Nobuhiro、Saito Hidetsugu、Hibi Toshifumi、Miura Soichiro、Hokari Ryota、Kanai Takanori
- Journal Title
  
  Journal of Hepatology
  
  Volume: 67 Issue: 4 Pages: 780-790
- DOI
  10.1016/j.jhep.2017.05.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08756, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15K09021, KAKENHI-PROJECT-15K19348, KAKENHI-PROJECT-15K09031
[Journal Article] Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice2017
- Author(s)
  Hayashi Atsushi、Mikami Yohei、Miyamoto Kentaro、Kamada Nobuhiko、Sato Toshiro、Mizuno Shinta、Naganuma Makoto、Teratani Toshiaki、Aoki Ryo、Fukuda Shinji、Suda Wataru、Hattori Masahira、Amagai Masayuki、Ohyama Manabu、Kanai Takanori
- Journal Title
  
  Cell Reports
  
  Volume: 20 Issue: 7 Pages: 1513-1524
- DOI
  10.1016/j.celrep.2017.07.057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-17H06176, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15K19348
[Journal Article] 今月の主題非特異性多発性小腸潰瘍症/CEAS─遺伝子異常と類縁疾患主題非特異性多発性小腸潰瘍症/CEASの内視鏡所見2017
- Author(s)
  細江直樹、緒方晴彦、宮永亮一、木村佳代子、高林馨、長沼誠、久松理一、今枝博之、岩男泰、金井隆典、松本主之
- Journal Title
  
  胃と腸
  
  Volume: 52 Issue: 11 Pages: 1423-1429
- DOI
  10.11477/mf.1403201192
- ISSN
  0536-2180, 1882-1219
- Year and Date
  2017-10-25
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974
[Journal Article] The risk factor of clinical relapse in ulcerative colitis patients with low dose 5-aminosalicylic acid as maintenance therapy: A report from the IBD registry2017
- Author(s)
  Tomohiro Fukuda, Makoto Naganuma, Shinya Sugimoto, Kosaku Nanki, Shinta Mizuno, Makoto Mutaguchi, Yoshihiro Nakazato, Nagamu Inoue, Haruhiko Ogata, Yasushi Iwao, Takanori Kanai
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 11 Pages: 935-47
- DOI
  10.1371/journal.pone.0187737
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K08974
[Journal Article] Efficacy of Indigo naturalis in a Multicenter Randomized Controlled Trial of Patients with Ulcerative Colitis2017
- Author(s)
  .Naganuma M, Sugimoto S, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka K, Hisamatsu T, Watanabe K, Mizuno S, Suda W, Hattori M, Fukuda S, Hirayama A, Abe T, Watanabe M, Hibi T, Suzuki Y, Kanai T
- Journal Title
  
  Gastroenterology
  
  Volume: 4 Issue: 4 Pages: 935-947
- DOI
  10.1053/j.gastro.2017.11.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K08564, KAKENHI-PROJECT-15K21364, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-16K09326
[Journal Article] Commensal Lactobacillus controls immune tolerance during acute liver injury in mice2017
- Author(s)
  Nakamoto N, Amiya T, Aoki R, Taniki N, Koda Y, Miyamoto K, Teratani T, Suzuki T, Chiba S, Chu PS, Hayashi A, Yamaguchi A, Shiba S, Miyake R, Katayama T, Suda W, Mikami Y, Kamada N, Ebinuma H, Saito H, Hattori M, Kanai T
- Journal Title
  
  Cell Reports
  
  Volume: 5 Issue: 5 Pages: 1215-1226
- DOI
  10.1016/j.celrep.2017.10.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15K09021
[Journal Article] Ulcerative colitis endoscopic index of severity is associated with long-term prognosis in ulcerative colitis patients treated with infliximab.2016
- Author(s)
  Saigusa K. Matsuoka K. Sugimoto S, Arai M, Kiyohara H, Takeshita K, Mizuno S, Mori K, Nanki K, Takeshita T, Nakazato Y, Yajima T, Naganuma M, Hisamatsu T, Ogata H, Iwao Y, Kanai T.
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 28 Pages: 665-70
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08974
[Journal Article] Findings of ulceration and severe stricture on MRE can predict prognosis of Crohn's disease in patients treated with anti-TNF treatment.2016
- Author(s)
  Naganuma M, Okuda S, Hisamatsu T, Matsuoka K, Mori K, Hosoe N, Nakazato Y, Ogata H, Kanai T.
- Journal Title
  
  Abdom Radiol (NY).
  
  Volume: 42(1) Issue: 1 Pages: 141-151
- DOI
  10.1007/s00261-016-0878-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15K15298
[Journal Article] Up-to-date medical treatment for ulcerative colitis2016
- Author(s)
  Kiyohara H, Mizuno S, Naganuma M, Kanai T
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 113 Issue: 3 Pages: 413-423
- DOI
  10.11405/nisshoshi.113.413
- NAID
  130005131305
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] Endoscopic Severity Predicts Long-Term Prognosis in Crohn's Disease Patients with Clinical Remission.2016
- Author(s)
  Naganuma M, Hisamatsu T, Matsuoka K, Kiyohara H, Arai M, Sugimoto S, Mori K, Nanki K, Ohno K, Mutaguchi M, Mizuno S, Bessho R, Nakazato Y, Hosoe N, Inoue N, Iwao Y, Ogata H, Kanai T
- Journal Title
  
  Digestion
  
  Volume: 93 Issue: 1 Pages: 66-71
- DOI
  10.1159/000441767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974
[Journal Article] Indole compounds may be promising medicines for ulcerative colitis.2016
- Author(s)
  Sugimoto S, Naganuma M, Kanai T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51(9) Issue: 9 Pages: 853-61
- DOI
  10.1007/s00535-016-1220-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-16K09326
[Journal Article] Findings of ulceration and severe stricture on MRE can predict prognosis of Crohn's disease in patients treated with anti-TNF treatment.2016
- Author(s)
  Naganuma M, Okuda S, Hisamatsu T, Matsuoka K, Mori K, Hosoe N, Nakazato Y, Ogata H, Kanai T.
- Journal Title
  
  Abdom Radiol (NY)
  
  Volume: 42(1) Pages: 141-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298
[Journal Article] Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial.2016
- Author(s)
  Matsumoto T, Motoya S, Watanabe K, Hisamatsu T, Nakase H, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 10(11) Pages: 1259-1266
- Data Source
  KAKENHI-PROJECT-15H02534
[Journal Article] A Single Species of Clostridium Subcluster XIVa Decreased in Ulcerative Colitis Patients2016
- Author(s)
  Takeshita K, Mizuno S, Mikami Y, Sujino T, Saigusa K, Matsuoka K, Naganuma M, Sato T, Takada T, Tsuji H, Kushiro A, Nomoto K, Kanai T
- Journal Title
  
  Inflamm Bowel Diｓ
  
  Volume: 22 Issue: 12 Pages: 2802-2810
- DOI
  10.1097/mib.0000000000000972
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-26293177, KAKENHI-PROJECT-15K15297, KAKENHI-PROJECT-15K08974
[Journal Article] Endoscopic morphologic features of ulcerative colitis-associated dysplasia classified according to the SCENIC consensus statement2016
- Author(s)
  Sugimoto S, Naganuma M, Iwao Y, Matsuoka K, Shimoda M, Mikami S, Mizuno S, Nakazato Y, Nanki K, Inoue N, Ogata H, Kanai T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 85(3) Issue: 3 Pages: 639-646
- DOI
  10.1016/j.gie.2016.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-16K08657
[Journal Article] The Ulcerative Colitis Endoscopic Index of Severity (UCEIS) is useful to predict medium to long-term prognosis in ulcerative colitis patients with clinical remission.2016
- Author(s)
  Arai M, Naganuma M, Sugimoto S, Kiyohara H, Ono K, Mori K, Saigusa K, Nanki K, Mutaguchi M, Mizuno S, Bessho R, Nakazato Y, Hosoe N, Matsuoka K, Inoue N, Ogata H, Iwao Y, Kanai T.
- Journal Title
  
  J Crohns Colitis
  
  Volume: 10(11) Issue: 11 Pages: 1303-1309
- DOI
  10.1093/ecco-jcc/jjw104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15K08974
[Journal Article] Adalimumab Monotherapy and a Combination with Azathioprine for Crohn's Disease: A Prospective, Randomized Trial.2016
- Author(s)
  Matsumoto T, Motoya S, Watanabe K, Hisamatsu T, Nakase H, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 10(11) Pages: 1259-1266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298
[Journal Article] A colorectal tumor organoid library demonstrates progressive loss of niche factor requirements.2016
- Author(s)
  Fujii M, Shimokawa M, Date S, Takano A, Matano M, Ohta Y, Nanki K, Kawasaki K, Nakazato Y, Uraoka T, Watanabe T, Kanai T, Sato T.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 18 Issue: 6 Pages: 827-838
- DOI
  10.1016/j.stem.2016.04.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-26115001, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-16H02672, KAKENHI-PROJECT-15J06065, KAKENHI-PROJECT-16J04984, KAKENHI-PROJECT-16J06433, KAKENHI-PROJECT-26293177, KAKENHI-PROJECT-15K15297, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15K19349, KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-16K09325
[Journal Article] Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study.2016
- Author(s)
  Sugimoto S, Naganuma M, Kiyohara H, Arai M, Ono K, Mori K, Saigusa K, Nanki K, Takeshita K, Takeshita T, Mutaguchi M, Mizuno S, Ogata H, Iwao Y, Kanai T
- Journal Title
  
  Digestion
  
  Volume: 93 Issue: 3 Pages: 193-201
- DOI
  10.1159/000444217
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15K15298
[Journal Article] Association of Visceral Fat Area, Smoking, and Alcohol Consumption with Reflux Esophagitis and Barrett's Esophagus in Japan.2015
- Author(s)
  Matsuzaki J, Suzuki H, Kobayakawa M, Inadomi JM, Takayama M, Makino K, Iwao Y, Sugino Y, Kanai T
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 7 Pages: 1-15
- DOI
  10.1371/journal.pone.0133865
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-26670065, KAKENHI-PROJECT-26860527, KAKENHI-PROJECT-25293178
[Journal Article] Modelling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids.2015
- Author(s)
  Matano M,Date S, Shimokawa M, Takano A, Fujii M, Ohta Y, Watanabe T, Kanai T, Sato T.
- Journal Title
  
  Nature Medicine
  
  Volume: 21(3) Issue: 3 Pages: 256-262
- DOI
  10.1038/nm.3802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-25670372, KAKENHI-PROJECT-25670570, KAKENHI-PROJECT-25860560, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-26293177, KAKENHI-PROJECT-26860528, KAKENHI-PROJECT-15K19349, KAKENHI-PROJECT-25253080
[Journal Article] Inflammatory bowel disease and bone decreased bone mineral density2015
- Author(s)
  Hisamatsu T, Wada Y, Kanai T
- Journal Title
  
  Clin Calcium
  
  Volume: 25(11) Pages: 1639-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H02534
[Journal Article] Decreased Plasma Histidine Level Predicts Risk of Relapse in Patients with Ulcerative Colitis in Remission.2015
- Author(s)
  Hisamatsu T, Ono N, Imaizumi A, Mori M, Suzuki H, Uo M, Hashimoto M, Naganuma M, Matsuoka K, Mizuno S, Kitazume MT, Yajima T, Ogata H, Iwao Y, Hibi T, Kanai T
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 10 Pages: 1-10
- DOI
  10.1371/journal.pone.0140716
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] Risk factors for decreased bone mineral density in inflammatory bowel disease: A cross-sectional study.2015
- Author(s)
  Wada Y, Hisamatsu T, Naganuma M, Matsuoka K, Okamoto S, Inoue N, Yajima T, Kouyama K, Iwao Y, Ogata H, Hibi T, Abe T, Kanai T
- Journal Title
  
  Clin Nutr
  
  Volume: 34 Issue: 6 Pages: 1202-9
- DOI
  10.1016/j.clnu.2015.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-26460977
[Journal Article] Computer-Aided Prediction of Long-Term Prognosis of Patients with Ulcerative Colitis after Cytoapheresis Therapy2015
- Author(s)
  7.Takayama T, Okamoto S, Hisamatsu T, Naganuma M, Matsuoka K, Mizuno S, Bessho R, Hibi T, Kanai T
- Journal Title
  
  PLoS One
  
  Volume: 10(6) Issue: 6 Pages: e0131197-e0131197
- DOI
  10.1371/journal.pone.0131197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] Crohn's Disease in which the Patient Developed Aortitis during Treatment with Adalimumab2015
- Author(s)
  6.Kiyohara H, Hisamatsu T, Matsuoka K, Naganuma M, Kameda H, Seta N, Takeuchi T, Kanai T
- Journal Title
  
  Intern. Med.
  
  Volume: 54 Issue: 14 Pages: 1725-1732
- DOI
  10.2169/internalmedicine.54.3853
- NAID
  130005088259
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] A breakthrough in probiotics: Clostridium butyricum regulates gut homeostasis and anti-inflammatory response in inflammatory bowel disease2015
- Author(s)
  Kanai T, Mikami Y, Hayashi A
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 50(9) Issue: 9 Pages: 928-39
- DOI
  10.1007/s00535-015-1084-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] Combination Therapy with Infliximab and Thiopurine Compared to Infliximab Monotherapy in Maintaining Remission of Postoperative Crohn's Disease2015
- Author(s)
  Sakuraba A, Okamoto S, Matsuoka K, Sato T, Naganuma M, Hisamatsu T, Iwao Y, Ogata H, Kanai T, Hibi T
- Journal Title
  
  Digestion.
  
  Volume: 91 Issue: 3 Pages: 233-8
- DOI
  10.1159/000375302
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08974, KAKENHI-PROJECT-15K15297, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-26293177
[Journal Article] Recent trends in diagnostic techniques for inflammatory bowel disease2015
- Author(s)
  Naganuma M, Hosoe N, Kanai T, Ogata H
- Journal Title
  
  Korean J Intern Med
  
  Volume: 30(3) Issue: 3 Pages: 271-8
- DOI
  10.3904/kjim.2015.30.3.271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] A Hereditary Enteropathy Caused by Mutations in the SLCO2A1 Gene, Encoding a Prostaglandin Transporter.2015
- Author(s)
  Umeno J, Hisamatsu T, Esaki M, Atsushi Hirano A, Kubokura N, Asano K, Kochi S, Yanai S, Fuyuno Y, Shimamura K, Hosoe N, Ogata H, Watanabe T, Aoyagi K, Ooi H, Watanabe K, Yasukawa S, Hirai F, Matsui T, Iida M, Yao T, Hibi T, Kosaki K, Kanai T, Kitazono T, Matsumoto T.
- Journal Title
  
  PLoS Genetics
  
  Volume: Nov 5;11(11): Issue: 11 Pages: 1-15
- DOI
  10.1371/journal.pgen.1005581
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04811, KAKENHI-PROJECT-25460953, KAKENHI-PROJECT-26860524
[Journal Article] Inflammatory bowel disease and bone decreased bone mineral density2015
- Author(s)
  Hisamatsu T, Wada Y, Kanai T
- Journal Title
  
  Clin Calcium.
  
  Volume: 25(11) Pages: 1639-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298
[Journal Article] Inflammatory bowel disease and the intestinal microbiota2015
- Author(s)
  3.Nanki K, Mizuno S, Naganuma M, Kanai T
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 112 Issue: 11 Pages: 1947-1955
- DOI
  10.11405/nisshoshi.112.1947
- NAID
  130005107575
- ISSN
  0446-6586, 1349-7693
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K15298, KAKENHI-PROJECT-15H02534
[Journal Article] Fecal Microbiota Transplantation for Gastrointestinal Diseases2014
- Author(s)
  Matsuoka K, Kanai T.
- Journal Title
  
  The Keio Journal of Medicine
  
  Volume: 63 Issue: 4 Pages: 69-74
- DOI
  10.2302/kjm.2014-0006-RE
- NAID
  130004713429
- ISSN
  0022-9717, 1880-1293
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24590951
[Journal Article] Endoscopic and pathologic changes of the upper gastrointestinal tract in Crohn's disease.2014
- Author(s)
  Sakuraba A, Iwao Y, Matsuoka K, Naganuma M, Ogata H, Kanai T, Hibi T. Endoscopic and pathologic changes of the upper gastroi ntestinal tract in Crohn's diseas
- Journal Title
  
  Biomed Res Int
  
  Volume: 2014 Pages: 610767-610767
- DOI
  10.1155/2014/610767
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice2014
- Author(s)
  Tomita, K. Teratani, T. Suzuki, T. Shimizu, M. Sato, H. Narimatsu, K. Okada, Y. Kurihara, C. Irie, R. Yokoyama, H. Shimamura, K. Usui, S. Ebinuma, H. Saito, H. Watanabe, C. Komoto, S. Kawaguchi, A. Nagao, S. Sugiyama, K. Hokari, R. Kanai, T. Miura, S. Hibi, T.
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 1 Pages: 154-169
- DOI
  10.1002/hep.26604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-24790719
[Journal Article] Cross-talk between RORgammat+ innate lymphoid cells and intestinal macrophages induces mucosal IL-22 production in Crohn's disease.2014
- Author(s)
  1.Mizuno S, Mikami Y, Kamada N, Handa T, Hayashi A, Sato T, Matsuoka K, Matano M, Ohta Y, Sugita A, Koganei K, Sahara R, Takazoe M, Hisamatsu T, Kanai T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 20(8) Issue: 8 Pages: 1426-1434
- DOI
  10.1097/mib.0000000000000105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-25670372, KAKENHI-PLANNED-26115007, KAKENHI-PROJECT-26293177, KAKENHI-PROJECT-26860528
[Journal Article] Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predjspose the liver to inflammation.2014
- Author(s)
  Mikami Y, Mizuno S, Nakamoto N, Hayashi A, Sujino T, Sato T, Kamada N, Matsuoka K, Hisamatsu T, Ebinuma H, Hibi T, Yoshimura A, Kanai T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 1-1
- DOI
  10.1371/journal.pone.0084619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] Diet, microbiota, and inflammatory bowel disease: lessons from Japanese foods2014
- Author(s)
  Kanai T, Matsuoka K, Naganuma M, Hayashi A, Hisamatsu T.
- Journal Title
  
  Korean J Intern Med.
  
  Volume: 29(4) Issue: 4 Pages: 409-415
- DOI
  10.3904/kjim.2014.29.4.409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190
[Journal Article] Surveillance using trimodal imaging endoscopy after endoscopic submucosal dissection for superficial gastric neoplasia.2014
- Author(s)
  Imaeda H, Hosoe N, Kashiwagi K, Ida Y, Nakamura R, Suzuki H, Saito Y, Yahagi N, Iwao Y, Kitagawa Y, Hibi T, Ogata H, Kanai T.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20(43) Issue: 43 Pages: 16311-7
- DOI
  10.3748/wjg.v20.i43.16311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-26670065
[Journal Article] Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis2014
- Author(s)
  Usui S, Hosoe N, Matsuoka K, Kobayashi T, Nakano M, Naganuma M, Ishibashi Y, Kimura K, Yoneno K, Kashiwagi K, Hisamatsu T, Inoue N, Serizawa H, Hibi T, Ogata H, Kanai T.
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 26(5) Issue: 5 Pages: 665-72
- DOI
  10.1111/den.12269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25460960
[Journal Article] Bone marrow-mesenchymal stem cells are a major source of interleukin-7 and sustain colitis by forming the niche for colitogenic CD4+ memory T cells.2013
- Author(s)
  Nemoto Y, Nakamura T, Watanabe M et al
- Journal Title
  
  Gut.
  
  Volume: 62 Issue: 8 Pages: 1142-1152
- DOI
  10.1136/gutjnl-2012-302029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-23659394, KAKENHI-PROJECT-23790777, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367, KAKENHI-PLANNED-23102003, KAKENHI-PUBLICLY-23130506
[Journal Article] A Single Strain of Clostridium butyricum Induces Intestinal I L-10-Producing Macrophages to Suppress Acute Exlperimental Colitis in Mice.2013
- Author(s)
  Hayashi A, Sato T, Kamada N, Mikami Y, Matsuoka K, Hisamatsu T, Hlbi T, Roers A, Yagita H, Ohteki T, Yoshimura A, Kanai T.
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 6 Pages: 711-22
- DOI
  10.1016/j.chom.2013.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] Th1/Th17-Mediated Interstitial Pneumonia in Chronic Colitis Mice Independent of Intestinal Microbiota.2013
- Author(s)
  Nemoto Y, Watanabe M et al
- Journal Title
  
  J Immunol.
  
  Volume: 190 Issue: 12 Pages: 6616-6625
- DOI
  10.4049/jimmunol.1202930
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22229005, KAKENHI-PROJECT-23590934, KAKENHI-PROJECT-24590935, KAKENHI-PROJECT-24590936, KAKENHI-PROJECT-24659375, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704, KAKENHI-PROJECT-25293170, KAKENHI-PROJECT-25670367
[Journal Article] Mucosal CXCR4_+ IgG plasma cells contribute to the pathogenesis of humanulcerative colitis through FcyR-mediated CD14_+ macrophage activation.2013
- Author(s)
  Uo M, Hisamatsu, T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K, Matsuoka K. Kanai T. Hibi T.
- Journal Title
  
  Gut
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190
[Journal Article] Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin.2013
- Author(s)
  Takabayashi K, Kashiwagi K, Kawata T, Sato T, Matsuoka K, Hisamatsu T, Takaishi H, Hibi T, Ogata H, Yahagi N, Kitagawa Y, Shigematsu N, Kanai T.
- Journal Title
  
  Cancer Biol Ther.
  
  Volume: 15(1) Issue: 1 Pages: 81-8
- DOI
  10.4161/cbt.26610
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14 macrophage activation2013
- Author(s)
  Uo M
- Journal Title
  
  Gut
  
  Volume: in press Issue: 12 Pages: 1734-44
- DOI
  10.1136/gutjnl-2012-303063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590951, KAKENHI-PROJECT-24659375
[Journal Article] Applicability of second generation colon capsule endoscope to ulcerative colitis: A clinical feasibility study.2013
- Author(s)
  Hosoe N, Matsuoka K, Naganuma M, Ida Y, Ishibashi Y, Kimura K, Yoneno K, Usui S, Kashiwagi K, Hisamatsu T, Inoue N, Kanai T, Imaeda H, Ogata H, Hibi T.
- Journal Title
  
  Gastroenterol Hepatol.
  
  Volume: 28 Issue: 7 Pages: 1174-1179
- DOI
  10.1111/jgh.12203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients.2013
- Author(s)
  Miyoshi J, Matsuoka K, Inoue N, Hisamatsu T, Ichikawa R, Yajima T, Okamoto S, Naganuma M, Sato T, Kanai T, Ogata H, Iwao Y, Hibi
- Journal Title
  
  J Crohns Colitis
  
  Volume: 7 Issue: 12 Pages: e609-e614
- DOI
  10.1016/j.crohns.2013.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice.2013
- Author(s)
  Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi. A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T.
- Journal Title
  
  Immunology Letters
  
  Volume: 150 Issue: 1-2 Pages: 123-9
- DOI
  10.1016/j.imlet.2013.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] IL-22-Producing RORyt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis.2013
- Author(s)
  Matsumoto A, Kanai T, Mikami Y, Chu PS, Nakamoto N, Ebinuma H, Saito H, Sato T, Yagita H, Hibi T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e62853-e62853
- DOI
  10.1371/journal.pone.0062853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.2013
- Author(s)
  Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito H, Hibi T.
- Journal Title
  
  Hepatology
  
  Volume: 58 Issue: 1 Pages: 337-350
- DOI
  10.1002/hep.26351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046
[Journal Article] Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy.2013
- Author(s)
  Takayama T, Kanai T, Matsuoka K, Okamoto S, Sujino T, Mikami Y, Hisamatsu T, Yajima T, Iwao Y, Ogata H, Hibi T
- Journal Title
  
  J Crohns Colitis
  
  Volume: 7(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Bone marrow mesenchymal stem cells are major source of IL-7 and sustain colitis by forming the niche for colitogenic CD4_+ memory T cells.2013
- Author(s)
  Nemoto Y, Kanai T, Takahara M, Oshima S, Nakamura T, Okamoto R, Tsuchiya S, Watanabe M.
- Journal Title
  
  Gut
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190
[Journal Article] Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy.2012
- Author(s)
  Takayama T, Kanai T, Matsuoka K, Okamoto S, Sujino T, Mikami Y, Hisamatsu T, Yajima T, Iwao Y, Ogata H, Hibi T.
- Journal Title
  
  Journal of Crohns and Colitis
  
  Volume: 7 Issue: 2 Pages: e49-e54
- DOI
  10.1016/j.crohns.2012.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-22590763, KAKENHI-PROJECT-23590949
[Journal Article] Novel technique of endoscopic submucosal dissection by using external forceps for early rectal cancer (with videos).2012
- Author(s)
  Imaeda H, Hosoe N, Ida Y, Nakamizo H, Kashiwagi K, Kanai T, Iwao Y, Hibi T,Ogata H.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 75 (6) Pages: 1253-1257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice.2012
- Author(s)
  Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 143 Issue: 5 Pages: 1288-1297
- DOI
  10.1053/j.gastro.2012.07.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-22590763, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375
[Journal Article] Long-term prognosis of patients with ulcerative colitis treated with cytapheresis therapy.2012
- Author(s)
  Takayama T, Kanai T, Matsuoka K, Okamoto S, Sujino T, Mikami Y, Hisamatsu T, Yajima T, Iwao Y, Ogata H, Hibi T.
- Journal Title
  
  Journal of Crohn’s and Colitis.
  
  Volume: 7(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] CCR9+macrophages are required for acute liver inflammation in mouse models of hepatitis2012
- Author(s)
  Nakamoto N, Kanai T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 366-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis.2012
- Author(s)
  Nakamoto N, Ebinuma H, Kanai T, Chu PS, Ono Y, Mikami Y, Ojiro K, Lipp M, Love PE, Saito H, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 366-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590744
[Journal Article] CCR9+ macrophages are required for acute liver inflammation in mouse models of hepatitis2012
- Author(s)
  Nakamoto N, Kanai T, et al., 他8名、3番目
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 366-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Anti-high mobility group box 1 and box 2 non-histone chromosomal proteins (HMGB1/HMGB2) antibodies and anti-Saccharomyces cerevisiae antibodies(ASCA): accuracy in differentially diagnosing UC and CD and correlation with inflammatory bowel disease phenotype.2012
- Author(s)
  Takaishi H, Kanai T, Nakazawa A, Sugata F, Nikai A, Yoshizawa S, Hamamoto Y, Funakoshi S, Yajima T, Iwao Y, Takemura M, Ozaki S, Hibi T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 47(9) Issue: 9 Pages: 969-977
- DOI
  10.1007/s00535-012-0566-3
- NAID
  10031122083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] RORγt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation2012
- Author(s)
  Kanai T, et al.
- Journal Title
  
  Mucosal Immunology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Bile acids induce monocyte differentiation toward IL-12 hypo-producing dendritic cells via a TGR5-depenclent pathway2012
- Author(s)
  Ichikawa R, Kanai T, et al.(他10名、10番目)
- Journal Title
  
  Immunology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Dysregulated balance of retinoid-related orphan receptor _Yt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis.2012
- Author(s)
  Kimura K, Kanai T, Hayashi A, Mikami Y, Sujino T, Mizuno S, Handa T, Matsuoka K, Hisamatsu T, Sato T, Hibi T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 427 Issue: 4 Pages: 694-700
- DOI
  10.1016/j.bbrc.2012.09.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PROJECT-24659374
[Journal Article] ROR_Yt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation2012
- Author(s)
  Kanai T, et al., 他5名、1番目
- Journal Title
  
  Mucosal Immunology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease.2012
- Author(s)
  Hisamatsu T, Okamoto S, Hashimoto M, Muramatsu T, Andou A, Uo M, Kitazume MT, Matsuoka K, Yajima T, Inoue N, Kanai T, Ogata H, Iwao Y, Yamakado M, Sakai R, Ono N, Ando T, Suzuki M ,Hibi T
- Journal Title
  
  PLoS ONE.
  
  Volume: 7(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] ROR_Yt-dependent IL-17A-producing cells in the pathogenesis of intestinal inflammation.2012
- Author(s)
  Kanai T, Mikami Y, Sujino T, Hisamatsu T, Hibi T.
- Journal Title
  
  Mucosal Immunology
  
  Volume: 5 Issue: 3 Pages: 240-247
- DOI
  10.1038/mi.2012.6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24659375
[Journal Article] The development of colitogenic CD4(+) T cells is regulated by IL-7 in collaboration with NK cell function in a murine model of colitis2012
- Author(s)
  Yamaji O, Kanai T, et al.(他11名、12番目)
- Journal Title
  
  J Immunol
  
  Volume: 188 Pages: 2524-2536
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease2012
- Author(s)
  Hisamatsu T, Kanai T, et al.(他17名、11番目)
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] CCL2-Induced Migration and SOCS3-Mediated Activation of Macrophages Are Involved in Cerulein-Induced Pancreatitis in Mice2012
- Author(s)
  Saeki K, Kanai T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 1010-1020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] CCR9(+) plasmacytoid dendritic cells in the small intestine suppress development of intestinal inflammation in mice.2012
- Author(s)
  Mizuno S, Kanai T, Mikami Y, Sujino T, Ono Y, Hayashi A, Handa T,Matsumoto A, Nakamoto N, Matsuoka K, Hisamatsu T, Takaishi H, Hibi T.
- Journal Title
  
  Immunol Lett
  
  Volume: 146 Pages: 64-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590744
[Journal Article] The development of colitogenic CD4(+) T cells is regulated by IL-7 in collaboration with NK cell function in a murine model of colitis2012
- Author(s)
  Yamaji O, Nagaishi T, Totsuka T, Onizawa M, Suzuki M, Tsuge N, Hasegawa A, Okamoto R, Tsuchiya K, Nakamura T, Arase H, Kanai T, Watanabe M.
- Journal Title
  
  J Immunol
  
  Volume: 188 Issue: 4 Pages: 2524-36
- DOI
  10.1152/ajpgi.00071.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659375
[Journal Article] T-helper 17 and interleukin-17-producing lymphoid tissue inducer-like T cells make different contributions to colitis in mice.2012
- Author(s)
  Ono Y, Kanai T, Sujino T, Nemoto y Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, 09ata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 148(Epub 2012 Jul 28.) Pages: 1288-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390190
[Journal Article] A high-cholesterol diet exacerbates liver fibrosis in mice via accumulation of free cholesterol in hepatic stellate cells2012
- Author(s)
  Teratani T, Kanai T, et al.(他16名、16番目)
- Journal Title
  
  Gastroenterology
  
  Volume: 142 Pages: 152-164
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells2011
- Author(s)
  Sujino T, Kanai T, Hisamatsu T, Hibi T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 141(3) Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] A case of beef tapeworm (Taenia saginata) infection observed by using video capsule endoscopy and radiography.2011
- Author(s)
  Hosoe N, Imaeda H, Okamoto S, Bessho R, Ida Y, Kobayashi S, Kanai T, Hibi T, Ogata H.
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 74(3) Pages: 690-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells2011
- Author(s)
  Sujino T, Kanai T, Ono Y, Mikami Y, et al
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Issue: 3 Pages: 1014-1023
- DOI
  10.1053/j.gastro.2011.05.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790667, KAKENHI-PROJECT-23590949
[Journal Article] A case of beef tapeworm (Taenia saginata) infection observed by using video capsule endoscopy and radiography (with videos)2011
- Author(s)
  Hosoe N, Imaeda H, Okamoto S, Bessho R, Saito R, Ida Y, Kobayashi S, Kanai T, Hibi T, Ogata H
- Journal Title
  
  Gastrointest Endosc
  
  Volume: 74 Pages: 690-691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells.2011
- Author(s)
  Sujino T, Kanai T, Ono Y, Mikami Y, Hayashi A, Doi T, Matsuoka K, Hisamatsu T, Takaishi H, Ogata H, Yoshimura A, Littman DR, Hibi T
- Journal Title
  
  Gastroenterology.
  
  Volume: 141(3) Pages: 1014-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease.2011
- Author(s)
  Miyoshi J, Yajima T, Okamoto S, Matsuoka K, Inoue N, Hisamatsu T, Shimamura K, Nakazawa A, Kanai T, Ogata H, Iwao Y, Mukai M, Hibi T
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(9) Pages: 1056-63
- NAID
  10029706720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells2011
- Author(s)
  Sujino T, Kanai T, Ono Y, Mikami Y, Hayashi A, Doi T, Matsuoka K, Hisamatsu T, Takaishi H, Ogata H, Yoshimura A, Littman DR, Hibi T
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Upregulated IL-7 receptor (alpha) expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y, Kanai T, Kameyama K, Okamoto R, Tsuchiya K, Nakamura T, Totsuka T, Ikuta K, Watanabe M
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Upregulated IL-7 receptor (alpha) expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y, Kanai T, Kameyama K, Okamoto R, Tsuchiya K, Nakamura T, Totsuka T, Ikuta K, Watanabe M
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis2011
- Author(s)
  Bessho R, Kanai T, Hosoe N, Kobayashi T, Takayama T, Inoue N, Mukai M, Qgata H, Hibi T
- Journal Title
  
  J Gastroenterol
  
  Volume: 46 Pages: 1197-1202
- NAID
  10030294462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2011
- Author(s)
  Takada Y, Kanai T, et al.
- Journal Title
  
  J Immunol
  
  Volume: 184 Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011
- Author(s)
  Miyoshi J, Hisamatsu T, Kanai T, Hibi T, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(9) Pages: 1056-1063
- NAID
  10029706720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Correlation between endocytoscopy and conventional histopathology in microstructural features of ulcerative colitis.2011
- Author(s)
  Bessho R, Kanai T, Hosoe N, Kobayashi T, Takayama T, Inoue N, Mukai M, Ogata H, Hibi T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 46 Pages: 1197-202
- NAID
  10030294462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Upregulated IL-7 receptor(alpha) expression on colitogenic memory CD4+T cells may participate in the development and persistence of chronic colitis2011
- Author(s)
  Shinohara T, Kanai T, et al.
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages.2011
- Author(s)
  Naruse H, Hisamatsu T, Yamauchi Y, Chang JE, Matsuoka K, Kitazume MT, Arai K, Ando S, Kanai T, Kamada N, Hibi T.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: Feb24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages Clin Exp Immunol2011
- Author(s)
  Naruse H, Hisamatsu T, Kanai T, Hibi T, et al.
- Volume
  164(1)
- Pages
  137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011
- Author(s)
  Miyoshi J, Yajima T, Okamoto S, Matsuoka K, Inoue N, Hisamatsu T, Shimamura K, Nakazawa A, Kanai T, Ogata H, Iwao Y, Mukai M, Hibi
- Journal Title
  
  J Gastroenterol
  
  Volume: 46( 9) Pages: 1056-1063
- NAID
  10029706720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949
[Journal Article] Upregulated IL-7 receptor (alpha) expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis.2011
- Author(s)
  Shinohara T, Nemoto Y, Kanai T, Kameyama K, Okamoto R, Tsuchiya K, Nakamura T, Totsuka T, Ikuta K, Watanabe M
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Luminal CD4^+ T cells penetrate gut epithelial monolayers and egress from lamina propria to blood circulation2011
- Author(s)
  Nemoto Y, Kanai T, et al.(他8名、2番目)
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Pages: 2130-2139
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Evaluation of small-intestinal abnormalities in adult patients with Henoch-Schonlein purpura using video capsule.2011
- Author(s)
  Ichikawa R, Hosoe N, Imaeda H, Takabayashi K, Bessho R, Ida Y, Naganuma M, Hisamatsu T, Inoue N, Kanai T, Iwao Y, Mukai M, Hibi T, Ogata H.
- Journal Title
  
  Endoscopy
  
  Volume: 43(2) Pages: 162-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Upregulated IL-7 receptor α expression on colitogenic memory CD4+ T cells may participate in the development and persistence of chronic colitis2011
- Author(s)
  Shinohara T, Kanai T, et al.(他8名、3番目)
- Journal Title
  
  J Immunol
  
  Volume: 186 Pages: 2623-2632
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages2011
- Author(s)
  Naruse H, Hisamatsu T, Kanai T, Hibi T, et al, 他7名、11番目
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 164(1) Pages: 137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Regulatory T cells suppress development of colitis, blocking differentiation of T-helper 17 into alternative T-helper 1 cells2011
- Author(s)
  Sujino T, Kanai T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] CD4+CD25+ regulatory T cells suppress the development of colitis by blocking the differentiation from Th17 to alternative Th1 cells2011
- Author(s)
  Sujino T, Kanai T, Mikami Y, Ono Y, Hayashi A, Doi T, Matsuoka K, Hisamatsu T, Takaishi H, Ogata H, Yoshimura A, Dan R Littman, Hibi T
- Journal Title
  
  Gastroenterology
  
  Volume: 141 Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Evaluation of small-intestinal abnormalities in adult patients with Henoch-Schonlein purpura using video capsule2011
- Author(s)
  Ichikawa R, Hosoe N, Imaeda H, Takabayashi K, Bessho R, Ida Y, Naganuma M, Hisamatsu T, Inoue N, Kanai T, Iwao Y, Mukai M, Hibi T, Ogata H
- Journal Title
  
  Endoscopy
  
  Volume: 43 Pages: 162-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
- Journal Title
  
  J Immunol
  
  Volume: 184(5) Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T.
- Journal Title
  
  J Immunol.
  
  Volume: 184 Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] In vivo visualization of trophozoites in patients with amoebic colitis by using a newly developed endocytoscope.2010
- Author(s)
  Hosoe N, Kobayashi T, Kanai T, Bessho R, Takayama T, Inoue N, Imaeda H, Iwao Y, Kobayashi S, Mukai M, Ogata H, Hibi T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 72(3) Pages: 643-646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 40 Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.2010
- Author(s)
  Ojiro K, Ebinuma H, Nakamoto N, Wakabayashi K, Mikami Y, Ono Y, Po-Sung C, Usui S, Umeda R, Takaishi H, Yamagishi Y, Saito H, Kanai T, Hibi T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 399 Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.2010
- Author(s)
  Ojiro K, Ebinuma H, Nakamoto N, Wakabayashi K, Mikami Y, Ono Y, Po-Sung C, Usui S, Umeda R, Takaishi H, Yamagishi Y, Saito H, Kanai T, Hibi T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 399 Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T.
- Journal Title
  
  J Immunol.
  
  Volume: 184 Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. 16(4)
  
  Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis2010
- Author(s)
  Ojiro K, Kanai T, et al.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 399 Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
- Journal Title
  
  J Immunol 184(5)
  
  Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 40 Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 40 Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Imbalance of NKp44(+) NKp46(-) and NKp44(-) NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease2010
- Author(s)
  Takayama T, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 139(3) Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competitio between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis2010
- Author(s)
  Mikami Y, Kanai T, Hisamatsu T, Hibi T., et al.
- Journal Title
  
  Eur J Immunol
  
  Volume: 40(9) Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.2010
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 16(4) Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T.
- Journal Title
  
  J Immunol.
  
  Volume: 184 Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010
- Author(s)
  Kamada N, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 16(4) Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.2010
- Author(s)
  Ojiro K, Ebinuma H, Nakamoto N, Wakabayashi K, Mikami Y, Ono Y, Po-Sung C, Usui S, Umeda R, Takaishi H, Yamagishi Y, Saito H, Kanai T, Hibi T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 399 Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inone N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: Sep;40(9) Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis2010
- Author(s)
  Mikami Y, Kanai T, et al.
- Journal Title
  
  Eur J Immunol
  
  Volume: 40 Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22021038
[Journal Article] Imbalance of NKp44(+) NKp46(-) and NKp44(-) NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease2010
- Author(s)
  Takayama T, Kanai T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Imbalance of NKp44 (+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: Sep;139(3) Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010
- Author(s)
  Takada Y, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  J Immunol
  
  Volume: 184(5) Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590763
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis2009
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Akiba H, Okumura K, Yagita H, Watanabe M.
- Journal Title
  
  J Immunol. 182
  
  Pages: 6079-6087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4+memory T cells in chronic colitis2009
- Author(s)
  Tomita T, Kanai T, et al.
- Journal Title
  
  Eur J Immunol
  
  Volume: 39 Pages: 2737-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Long-lived colitogenic CD4+memory T cells residing outside the intestine participate in the perpetuation of chronic colitis2009
- Author(s)
  Nemoto Y, Kanai T, et al.
- Journal Title
  
  J Immunol
  
  Volume: 183 Pages: 5059-5068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Signaling pathway via TNF-{alpha}/NF-{kappa} B in intestinalepithelial cells may be directly involved in colitis-associatedcarcinogenesis.2009
- Author(s)
  Kanai T, Nemoto Y, Kamata M, Hisamatsu T, Watanabe M, Hibi T
- Journal Title
  
  Curr Opin Gastroenterol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function 0f CD4+CD25+regulatory T cells in chronic colitis2009
- Author(s)
  Totsuka T, Kanai T, et al.
- Journal Title
  
  J Immunol
  
  Volume: 182 Pages: 6079-6087
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable.2009
- Author(s)
  Kanai_T^*, Nemoto Y, Tomita T, Totsuka T, Watanabe M, Hibi T.
- Journal Title
  
  Inflamm Bowet Dis. 15
  
  Pages: 926-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis2009
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Akiba H, Okumura K, Yagita H, Watanabe M.
- Journal Title
  
  J Immunol 182
  
  Pages: 6079-6087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Long-lived colitogenic CD^<4+> memory T cells residing outside the intestine participate in the perpetuation of chronic colitis.2009
- Author(s)
  Nemoto Y, Kanai T^*, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sudo T, Matsumoto S, Watanabe M.
- Journal Title
  
  J Immunol. 183
  
  Pages: 5059-5068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Signaling pathway via TNFα/NFκB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Yagita H, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable2009
- Author(s)
  Kanai T, Nemoto Y, Tomita T, Totsuka T, Watanabe M, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. 15
  
  Pages: 926-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epit helia2009
- Author(s)
  Okamoto R, Kanai T, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296 Pages: 23-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Musashi-l suppresses expression of Paneth cell-specific genes inhuman intestinal epithelial cells.2009
- Author(s)
  Murayama M, Okamoto R, Tsuchi ya K, Akiyama J, Nakamura T, Sakamoto N, Kanai T, Watanabe M.
- Journal Title
  
  J Gastroenterol. 44
  
  Pages: 173-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4+ memory T cells in chronic colitis2009
- Author(s)
  Tomita T, Kanai T, Totsuka T, Nemoto Y, Okamoto R, Tsuchiya K, Sakamoto N, Ohteki T, Hibi T, Watanabe M.
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 2737-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia.2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakainura T, Kanai T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] IL-7 is essential for lymphopenia-driven turnover of colitogenic CD4+ memory T cells in chronic colitis.2009
- Author(s)
  Tomita T, Kanai T^*, Totsuka T, Nemoto Y, Okamoto R, Tsuchiya K, Sakamoto N, Ohteki T, Hibi T, Watanabe M.
- Journal Title
  
  Eur J Immunol. 39
  
  Pages: 2737-2747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability.2009
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  J Immunol. 183
  
  Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Signaling pathway via TNFα/NFκB in iatestinal epithelial cells may be directly invotved in colitis-associated carcinogenesis.2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T^*, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Yagita H., Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory boweldisease.2009
- Author(s)
  Kanai T^*, Nemoto Y, Kamada N, Totsuka T, Hisamatsu T, Watanabe M. Hibi T.
- Journal Title
  
  Curr Opin Gastroenterol. 22
  
  Pages: 306-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Signaling pathway via TNF-{alpha}/NF-{kappa} B in intestinal epithelial cells may be directly involved in Colitis-associated carcinogenesis.2009
- Author(s)
  Oni zawa M, Nagaishi T, Kanai T, Nagano K, 0shima S, Kemoto Y, Yoshi oka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Human CD14+macrophages in intestinal lamina propria exhibit potent a ntigen-presenting ability2009
- Author(s)
  Kamada N, Kanai T, et al.
- Journal Title
  
  J Immunol
  
  Volume: 183 Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4^<+> CD25^<+> regulatory T cells in chronic colitis2009
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Akiba H, Okumura K, Yagita H, Watanabe M
- Journal Title
  
  J Immunol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability2009
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  J Immunol. 183
  
  Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Homeostatic (IL-7) and effector (IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease2009
- Author(s)
  Kanai T, Nemoto Y, Kamada N, Totsuka T, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Curr Opin GastroenterolEpub ahead of print(Curr Opin Gastroenterol)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Persistent retention of colitogenic CD4+memory T cells causes inflammatory bowel diseases to become intaractable2009
- Author(s)
  Kanai T, et al.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 15 Pages: 926-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow2009
- Author(s)
  Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, Nakamura T, Tsuchiya K, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Requirement of Notch activation during regeneration of the intestinal epithelia2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T, Kanai T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
  
  Pages: 23-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Single-operator double-balloon endoscopy (DBE) is as effective as dual-operator DBE2009
- Author(s)
  Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Yoshioka S, Yoshioka A, Kanai T, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol(Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Single-operator double-balloon endoscopy (DBE)is as effectiveas dual-operator DBE.2009
- Author(s)
  Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Yoshioka S, Yoshioka A, Kanai T, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability2009
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
- Journal Title
  
  J Immunol. 183(3)
  
  Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Signaling pathway via TNF-{alpha}/NF-{kappa}B in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, Nagano K, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Requirement of Notch activation duringregeneration of the intestinal epithelia2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, AkiyamaJ, Nakamura T, Kanai T, Watanabe M
- Journal Title
  
  Am Jphysiol GI & Liver 296
  
  Pages: 23-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Signaling pathway via TNFα/NFκB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Kanai T, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 296 Pages: 850-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Persistent retention of colitogenic CD4(+)memory T cells causes inflammatory bowel diseases to become intractable2009
- Author(s)
  Kanai T, Nemoto Y, Kamata M, Hisamatsu T, Watanabe M, Hibi T
- Journal Title
  
  Curr Opin Gastroenterol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Requirement of Notch activation during regeneration of the intestin al epithelia2009
- Author(s)
  Okamoto R, Tsuchiya K, Nemoto Y, Akiyama J, Nakamura T. Kanai T. Watanabe M
- Journal Title
  
  Am J Physiol. Gastrointest Liver Physiol 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Long-lived colitogenic CD4+ memory T cells residing outside the intestine participate in the perpetuation of chronic colitis2009
- Author(s)
  Nemoto Y, Kanai T, Kameyama K, Shinohara T, Sakamoto N, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sudo T, Matsumoto S, Watanabe M.
- Journal Title
  
  J Immunol. 183
  
  Pages: 5059-5068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Persistent retention of colitogenic CD4+ memory T cells causes inflammatory bowel diseases to become intractable2009
- Author(s)
  Kanai T, Nemoto Y, Tomita T, Totsuka T, Watanabe M, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. 15
  
  Pages: 926-934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] RANKL2009
- Author(s)
  Totsuka T, Kanai T, Watanabe M.
- Journal Title
  
  J Immunol in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Homeostatic(IL-7) and effector(IL-17) cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease2009
- Author(s)
  Kanai T, et al.
- Journal Title
  
  Curr Opin Gastroenterol
  
  Volume: 22 Pages: 306-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells2009
- Author(s)
  Murayama M, Okamoto R, Tsuchiya K, Akiyama J, Nakamura T, Sakamoto N, Kanai T, Watanabe M.
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 173-182
- NAID
  10025173646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Persistent retention of Colitogenic CD4(+)memory T cells causes inflammatory bowel diseases to become intractable.2009
- Author(s)
  kanai T, Nemoto Y, Tomita T, Totsuka T, Watanabe M, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.2009
- Author(s)
  Totsuka T, Kanai T^*, Nemoto Y, Tomita T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Akiba H, Okumura K, Yagita H, Watanabe M
- Journal Title
  
  J Immunol. 182
  
  Pages: 6079-6087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Homeostatic(IL-7)and effector(IL-17)cytokines as distinct but complementary target for an optimal therapeutic strategy in inflammatory bowel disease2009
- Author(s)
  Kanai T, Nemoto Y, Kamada N, Totsuka T, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Curr Opin Gastroenterol. 22
  
  Pages: 306-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390233
[Journal Article] Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis2009
- Author(s)
  Onizawa M, Nagaishi T, Kanai T, Nagano K, Oshima S, Nemoto Y, Yoshioka A, Totsuka T, Okamoto R, Nakamura T, Sakamoto N, Tsuchiya K, Aoki K, Ohya K, Yagita H, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 296
  
  Pages: 850-859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Immunosenescent colitogenic CD4^+ T cells convert to regulatory cells and suppress colitis.2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M.
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Flagellin stimulation suppresses IL-7 secretion of intestinal epithelial cells2008
- Author(s)
  Yoshioka A, Okamoto R, Oshima S, Akiyama J, Tsuchiya K, Nakamura T, Kanai T, Watanabe M.
- Journal Title
  
  Cytokine 44
  
  Pages: 57-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Current pharmacologic therapies and emerging alternatives in the treatment of ulcerative colitis.2008
- Author(s)
  Nakamura T, Nagahori M, Kanai T, Watanabe M.
- Journal Title
  
  Digestion. 77
  
  Pages: 36-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Colitogenic CD4+effector-memory T cells actively recirculate in chroniccolitic mice.2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14(12)
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Negative feedback regulation of colitogenic CD4(+) T cells by increased granulopoiesis2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14(11)
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Continuous generation of colitogenic CD4^+ T cells in persistent colitis.2008
- Author(s)
  Toraita T, Kanai T, Fujii T, Nemoto Y, Okaraoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M.
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Continuous generation of colitogenic CD4(+) T cells in persistent colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M.
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Immunosenescent colitogenic CD4^<+> T cells convert to regulatory cells and suppress colitis2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Negative feedback regulation of colitogenic CD4(+)T cells by increased granulopoiesis.2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14(11)
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
- Journal Title
  
  J Immunol 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4^+ T cells in chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+ T cells in chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M
- Journal Title
  
  J Immunol 180(8)
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Inducible expression of microRNA-194 is regulated by HNF-1alpha during intestinal epithelial cell differentiation2008
- Author(s)
  Hino K, Tsuchiya K, Fukao T, Kiga K, Okamoto R, Kanai T, Watanabe M.
- Journal Title
  
  RNA 14
  
  Pages: 1433-1442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Immunosenescent colitogenic CD4(+) T cells convert to regulatory cells and suppress colitis2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M.
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Colitogenic CD4+ effector-memory T cells actively recirculate in chronic colitic mice2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M.
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Proteasomal degradalion of Atohl by aberrant Wnt signaling maintains the undifferentiated state of colon cancer.2008
- Author(s)
  Aragnki M, Tsuchiya K, Okamoto R, Yoshioka S. Nakamura T, Sakamoto N, Kanai T, Watanabe M.
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 923-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] FTY720 suppresses the development of colitis in lymphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow2008
- Author(s)
  Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, Nakamura T, Tsuchiya K, Okamoto R, Watanabe M.
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4^<+> T cells in chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, N emoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M
- Journal Title
  
  J Iinmunol 180
  
  Pages: 5291-5298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion and survival of colitogenic CD4+ T cells in chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M
- Journal Title
  
  J Immunol 180
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopath ogenicity and replication capacity.2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Mishima K, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Kanai T, Tsuchiya K, Wakita T, Enomoto N, Watanabe M.
- Journal Title
  
  Virology. 37
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Blockade of NKG2D signaling prevents the development of marine CD4^+ T cell-mediated colitis.2008
- Author(s)
  Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, Okumura K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Immunosenescent colitogenic CD4(+)T cells convert to regulatory cell sand suppress colitis.2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R, Watanabe M
- Journal Title
  
  Eur J Immunol. 38(5)
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4^+ T cell-mediated colitis.2008
- Author(s)
  Ito Y, Kanai T, et. al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 294
  
  Pages: 199-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Flagellin stimulation suppresses IL-7 secretion of intestinal epithelial cells.2008
- Author(s)
  Yoshioka A, Okamoto R, Oshima S, Akiyama J, Tsuchiya K, Nakamura T, Kanai T, Watanabe M.
- Journal Title
  
  Cytokine 44
  
  Pages: 57-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+ T cells in chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M.
- Journal Title
  
  J Immunol 180
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Continuous generation of colitogenic CD4(+)T cells in persistent colitis.2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M
- Journal Title
  
  Eur J Immunol. 38(5)
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4^+ T cells in chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M.
- Journal Title
  
  J Immunol. 180
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M.
- Journal Title
  
  J Immunol 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4+Tcell-mediated colitis.2008
- Author(s)
  Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, Okumura K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol. 294(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
- Journal Title
  
  J Immunol 180(1)
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Current pharmacologic therapies and emerging alternatives in the treatment of ulcerative colitis2008
- Author(s)
  Nakamura T, Nagahori M, Kanai T, Watanabe M.
- Journal Title
  
  Digestion 77
  
  Pages: 36-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] MyD88-dependent pathway in T cells directly modulates the expansion of colitogenic CD4+T cells in chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Akira S, Watanabe M
- Journal Title
  
  J Immunol. 180(8)
  
  Pages: 5291-5299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Systemic, but not intestinal. IL-7 is essential for the persistence of chroniccolitis.2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M
- Journal Title
  
  J Immunol. 180(1)
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Immunosenescent colitogenic CD4+ T cells convert to regulatory cells and suppress colitis.2008
- Author(s)
  Totsuka T, Kanai T, et. al.
- Journal Title
  
  European Journal of Immunology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Continuous generation of colitogenic CD4(+) Tcells in persistent colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, Nemoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M
- Journal Title
  
  Eur J Immunol 38(5)
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Proteasomal degradation of Atoh1 by aberrant Wnt signaling maintains the undifferentiated state of colon cancer2008
- Author(s)
  Aragaki M, Tsuchiya K, Okamoto R, Yoshioka S, Nakamura T, Sakamoto N, Kanai T, Watanabe M.
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 923-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Immunosenescent colitogenic CD4(+) T cells convert to regulatory cells and suppress colitis2008
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Tsuchiya K, Sakamoto N, Okamoto R,Watanabe M
- Journal Title
  
  Eur J Immunol 38(5)
  
  Pages: 1275-1286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4^+ T cell-mediated colitis.2008
- Author(s)
  Ito Y, Kanai T, et. al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 294(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Single-operator method for double-balloon endoscopy : a pilot study2008
- Author(s)
  Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Okamoto R, Kanai T, Watanabe M.
- Journal Title
  
  Endoscopy 40
  
  Pages: 936-938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Continuous generation of colitogenic CD4^<+> T cells in persistent colitis2008
- Author(s)
  Tomita T, Kanai T, Fujii T, N emoto Y, Okamoto R, Tsuchiya K, Totsuka T, Sakamoto N, Watanabe M
- Journal Title
  
  Eur J Immunol 38
  
  Pages: 1264-1274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060010
[Journal Article] Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis2008
- Author(s)
  Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, Okumura K, Yagita H, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 294
  
  Pages: 199-207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Development of plaque assays for hepatitis C virus-JFH1 strain and isolation of mutants with enhanced cytopathogenicity and replication capacity2008
- Author(s)
  Sekine-Osajima Y, Sakamoto N, Mishima K, Nakagawa M, Itsui Y, Tasaka M, Nishimura-Sakurai Y, Chen CH, Kanai T, Tsuchiya K, Wakita T, Enomoto N, Watanabe M.
- Journal Title
  
  Virology 371
  
  Pages: 71-85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] MyD88-dependent pathway in T Cells directly modulates the expansion of colitogenic CD4+ T Cells in chronic colitisl.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Colitogenic CD4^+ effector-memory T cells actively recirculate in chronic colitic mice.2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M.
- Journal Title
  
  Inflamm Bowel Dis. 14
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Colitogenic CD4^+ effector-memory T cellsactively recirculate in chronic coliticmice2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Immunosenescent colitogenic CD4^+T cells convert to regulatory cells and suppress colitis.2008
- Author(s)
  Totsuka T, Kanai T, et. al.
- Journal Title
  
  European Journal of Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Negative feedback regulationof colitogenic CD4+ T cells by increasedgranulopoiesis2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Inducible expression of micro RNA-194 is regulated by INF 1 during intestinal epithelial cell differntiation.2008
- Author(s)
  Hino K, Tsuchiya K, Fukao T, Kiga K. Okamoto R, Kanai T, Watanabe M.
- Journal Title
  
  RNA. 14
  
  Pages: 1433-1442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Continuous generation of colitogenic CD4^+T cells in persistent colitis.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  European Journal of Immunology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis2008
- Author(s)
  Ito Y, Kanai T, Totsuka T, Okamoto R, Tsuchiya K, Nemoto Y, Yoshioka A, Tomita T, Nagaishi T, Sakamoto N, Sakanishi T, Okumura K, Yagita H, Watanabe M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 294(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Sakamoto N, Watanabe M.
- Journal Title
  
  J Immunol 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Colitogenic CD4+ effector-memory T cells actively recirculate in chronic coliti0c mice2008
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T, Nozaki K, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 14(12)
  
  Pages: 1630-1640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Single-operator method for double-balloon endoscopy : a pilot study.2008
- Author(s)
  Araki A, Tsuchiya K, Okada E, Suzuki S, Oshima S, Okamoto R, Kanai T, Watanabe M.
- Journal Title
  
  Endoscopy. 40
  
  Pages: 963-938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] FTY720 suppresses the development of colitis in lyinphoid-null mice by modulating the trafficking of colitogenic CD4+ T cells in bone marrow.2008
- Author(s)
  Fujii T, Tomita T, Kanai T, Nemoto Y, Totsuka T, Sakamoto N, Nakamura T, Tsuchiya K, Okamoto R, Watanabe M.
- Journal Title
  
  Eur J Immunol. 38
  
  Pages: 3290-3303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Proteasomal degradation ofAtoh1 by aberrant Wnt signaling maintainsthe undifferentiated state of colon cancer2008
- Author(s)
  Aragaki M, Tsuchiya K, Okamoto R, Yoshioka S, Nakamura T, Sakamoto N, KanaiT, Watanabe M
- Journal Title
  
  Biochem Biophys Res Commun 368
  
  Pages: 923-929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis.2008
- Author(s)
  Tomita T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology 180
  
  Pages: 383-390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Intestinal lamina propriaretaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation2007
- Author(s)
  Makita S, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Yamamoto M, Kiyono H, Watanabe M
- Journal Title
  
  J Immunol 178
  
  Pages: 4937-4946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Makita S,Okamoto R, Tsuchiya K, Watanabe M
- Journal Title
  
  J Immunol 178
  
  Pages: 4737-4748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis2007
- Author(s)
  Nemoto Y, Kanai T, Makita S, Okamoto R, Totsuka T, Takeda K, Watanabe M
- Journal Title
  
  Gastroenterology 132(1)
  
  Pages: 176-189
- NAID
  40015644486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis.2007
- Author(s)
  Nemoto Y, Kanai T, et. al.
- Journal Title
  
  Gastroenterology 132
  
  Pages: 176-189
- NAID
  40015644486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14^<dull>CD16^+monocytes in leukocytapheresis therapy for ulcerative colitis.2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T, Watanabe M
- Journal Title
  
  Inflam Bowel Dis. 13・3
  
  Pages: 284-290
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis.2007
- Author(s)
  Totsuka T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 4737-4748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Extracorporeal Elimination of TNFα-Producing CD14 dullCD16 Monocytes in Leukocytapheresis Therapy for Ulcerative Colitis2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T,Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 284-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Bonemarrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis2007
- Author(s)
  Nemoto Y, Kanai T, Makita S, Okamoto R, Totsuka T, Takeda K, Watanabe M
- Journal Title
  
  Gastroenterology 132
  
  Pages: 176-189
- NAID
  40015644486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Intestinal lamina propria retaining CD4+CD25+ regulatory T cells is a suppressive site of intestinal inflammation2007
- Author(s)
  Makita S, Kanai T, Nemoto Y, Totsuka T, Okamoto R, Tsuchiya K, Yamamoto M, Kiyono H, Watanabe M
- Journal Title
  
  J Immunol 178(8)
  
  Pages: 4937-4946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14dull CDl6+monocytes in leukocytapheresis therapy for ulcerative colitis2007
- Author(s)
  Kanai T, Makita S, et. al.
- Journal Title
  
  Inflam Bowel Dis 13
  
  Pages: 284-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Reciprocal targetingof Hath1 and β-catenin by Wnt-glycogensynthase kinase 3βin human colon cancer2007
- Author(s)
  Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M
- Journal Title
  
  Gastroenterology 132
  
  Pages: 208-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590716
[Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer.2007
- Author(s)
  Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 208-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis running title : IL-7-dependent colitis.2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Makita S, Watanabe M
- Journal Title
  
  J Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis running title : IL-7-dependent colitis.2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Makita S, Watanabe M
- Journal Title
  
  J Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] IL-7 Is essential for the development and the persistence of chronic colitis2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Makita S, Okamoto R, Tsuchiya K, Watanabe M
- Journal Title
  
  J Immunol 178(8)
  
  Pages: 4737-4748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis.2007
- Author(s)
  Totsuka T, Kanai T, et. al.
- Journal Title
  
  Journal of Immunology 178
  
  Pages: 4737-4748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14^<dull>CD16^+ monocytes in leukocytapheresis therapy for ulcerative colitis.2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T, Watanabe M.
- Journal Title
  
  Inflam Bowel Dis. 13(3)
  
  Pages: 284-290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Reciprocal targeting of Hath1 and β-catenin by Wnt-glycogen synthase kinase 3β in human colon cancer.2007
- Author(s)
  Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 208-220
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] IL-7 is essential for the development and the persistence of chronic colitis running title : IL-7-dependent colitis.2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Makita S, Watanabe M
- Journal Title
  
  J Immunol. 178
  
  Pages: 4737-4748
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Reciprocal targeting of Hathl and β-catenin by Wnt-glycogen synthase kinase 3 β in human colon cancer.2007
- Author(s)
  Tsuchiya K, Nakamura T, Okamoto R, Kanai T, Watanabe M
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 208-220
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Intestinal Lamina Propria Retaining CD4+CD25+ Regulatory T Cells Is A Suppressive Site of Intestinal Inflammation.2007
- Author(s)
  Makita S, Kanai T, Nemoto Y, Totsuka T, Yamamoto M, Kiyono H, Watanabe M
- Journal Title
  
  J Immunol. 178
  
  Pages: 4937-4946
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14(dull)CD16(+) monocytes in leukocytapheresis therapy for ulcerative colitis2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis 13(3)
  
  Pages: 284-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590718
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14dullCD16+monocytes in leukocytapheresis therapy for ulcerative colitis.2007
- Author(s)
  Kanai T, Makita S, et. al.
- Journal Title
  
  Inflam Bowel Dis 13
  
  Pages: 284-290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD 14^<dull> CD16^+monocytes in leukocytapheresis therapy for ulcerative colitis.2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T, Watanabe M
- Journal Title
  
  Inflam Bowel Dis. 13・3
  
  Pages: 284-290
- Data Source
  KAKENHI-PROJECT-18659204
[Journal Article] Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis.2007
- Author(s)
  Nemoto Y, Kanai T, Makita S, Okamoto R, Totsuka T, Takeda K, Watanabe M
- Journal Title
  
  Gastroenterology. 132
  
  Pages: 176-189
- NAID
  40015644486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14^<dull> CD16^+monocytes in leukocytapheresis therapy for ulcerative colitis.2007
- Author(s)
  Kanai T, Makita S, Kawamura T, Kawamura T, Nemoto Y, Kubota D, Nagayama K, Totsuka T, Watanabe M
- Journal Title
  
  Inflam Bowel Dis. 13・3
  
  Pages: 284-290
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis.2007
- Author(s)
  Nemoto Y, Kanai T, et. al.
- Journal Title
  
  Gastroenterology 132
  
  Pages: 176-189
- NAID
  40015644486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390197
[Journal Article] Naturally arising CD4^+CD25^+ regulatory T cells suppress the expansion of colitogenic CD4^+CD44^<high>CD62L^- effector-memory T cells.2006
- Author(s)
  Kanai T, Tanimoto K, Nemoto Y, Fujii R, Makita S, Totsuka T, Watanabe M
- Journal Title
  
  Am J Physiol. 290
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.2006
- Author(s)
  Kanai T, Uraushihara K, Totsuka T, Nemoto Y, Fujii R, Kawamura T, Makita S, Yagita H, Okumura K, Watanabe M
- Journal Title
  
  J Gastroenterol Hepatol. 21
  
  Pages: 1136-1142
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Th1/Th2-mediated colitis induced by adoptive transfer of CD4^+CD45RB^<high> T lymphocytes into nude mice2006
- Author(s)
  Kanai T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 89-99
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Do fatty acids influence functions of intestinal dendritic cells?2006
- Author(s)
  Kanai T, Watanabe M
- Journal Title
  
  J Gastroenterol. 41
  
  Pages: 288-289
- NAID
  10017477519
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Naturally arising CD4^+CD25^+ regulatory T cells suppress the expansion of colitogenic CD4^+CD44^<high>CD62L^-effector-memory T cells.2006
- Author(s)
  Kanai T, Tanimoto K, Nemoto Y, Fujii R, Makita S, Totsuka T, Watanabe M
- Journal Title
  
  Am J Physiol. 290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Th1/Th2-mediated colitis induced by adoptive transfer of CD4+CD45RB^<high> T lymphocytes into nude mice2006
- Author(s)
  Kanai T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 89-99
- Data Source
  KAKENHI-PROJECT-17659211
[Journal Article] The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease2006
- Author(s)
  Kanai T, Hibi T, Watanabe M
- Journal Title
  
  Expert Opin Biol Ther. 6・5
  
  Pages: 453-466
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Th1/Th2-mediated colitis induced by adoptive transfer of CD4+CD45RB^<high> T lymphocytes into nude mice2006
- Author(s)
  Kanai T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Die 12
  
  Pages: 89-99
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] FTY720 suppresses CD4^+CD44^<high>CD62L^- effector memory T cell-mediated colitis.2006
- Author(s)
  Fujii R, Kanai T, Nemoto Y, Makita S, Oshima S, Okamoto R, Tsuchiya K, Totsuka T, Watanabe M
- Journal Title
  
  Am J Physiol. 291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] The logics of leucocytapheresis as a natural biological therapy for inflammatory bowel disease.2006
- Author(s)
  Kanai T, Hibi T, Watanabe M
- Journal Title
  
  Expert Opin Biol Ther. 6
  
  Pages: 453-466
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Extracorporeal elimination of TNF-alpha-producing CD14dullCD16+monocytes in leukocytapheresis therapy for ulcerative colitis.2006
- Author(s)
  Kanai T, Makita S, Kawamura T, Nemoto Y, Kubota D, Nagayama T, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis. 13
  
  Pages: 284-290
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] The logics of leukocytapheresis as a natural biological therapy for inflammatory bowel disease.2006
- Author(s)
  Kanai T, Hibi T, Watanabe M.
- Journal Title
  
  Expert Opin Biol Ther. 6(5)
  
  Pages: 453-466
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Th1/Th2-mediated colitis induced by adoptive transfer of CD4+CD45RBhigh T lymphocytes into nude mice.2006
- Author(s)
  Kanai T, Kawamura T, Dohi T, Makita S, Nemoto Y, Totsuka T, Watanabe M
- Journal Title
  
  Inflamm Bowel Dis. 12
  
  Pages: 89-99
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Inoue N, Hisamatsu T, Kashiwagi K, Takaishi H, Kanai T, Watanabe M, Ishii H, Hibi T.
- Journal Title
  
  J Gastrornt Hepatol 20
  
  Pages: 710-715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome2005
- Author(s)
  Namiki S, Kanai T, Watanabe M, et al.
- Journal Title
  
  FEBES Lett 579
  
  Pages: 2781-2787
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis.2005
- Author(s)
  Araki A, Kanai T, Ishikura T, Makita S, Uraushihara K, Iiyama R, Totsuka T, Takeda K, Akira S, Watanabe M.
- Journal Title
  
  J Gastroenterol 40
  
  Pages: 16-23
- NAID
  10014370953
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Regulation of murine chronic colitis by CD4^+CD25^- Programmed Death-1^+ T cells2005
- Author(s)
  Totsuka T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol 18
  
  Pages: 1773-1785
- Data Source
  KAKENHI-PROJECT-17659211
[Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome2005
- Author(s)
  Namiki S, Kanai T, Watanabe M, et al.
- Journal Title
  
  FEBES Lett 579
  
  Pages: 2781-2787
- Data Source
  KAKENHI-PROJECT-17659211
[Journal Article] Increase of bone maorrow-derived secretory lineage epithelial cells during regeneration in the human intestine2005
- Author(s)
  Matsumoto T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1851-1867
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] Regulation of murine chronic colitis by CD4^+CD25^- Programmed Death-1^+ T cells2005
- Author(s)
  Totsuka T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol 18
  
  Pages: 1773-1785
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine2005
- Author(s)
  Matsumoto T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1851-1867
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice2005
- Author(s)
  Okada E, Kanai T, Watanabe M, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+mucosal T cells in mice2005
- Author(s)
  Okada E, Kanai T, Watanabe M, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice2005
- Author(s)
  Okada E, Kanai T, Watanabe M, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7Rhigh CD4+ mucosal T cells in mice2005
- Author(s)
  Okada E, Kanai T, Watanabe et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Data Source
  KAKENHI-PROJECT-17659211
[Journal Article] Increase of bone maorrow-derived secretory lineage epithelial cells during regeneration in the human intestine2005
- Author(s)
  Matsumoto T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1851-1867
- Data Source
  KAKENHI-PROJECT-17659211
[Journal Article] MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis.2005
- Author(s)
  Araki A, Kanai T, et al.
- Journal Title
  
  J Gastroenterol 40
  
  Pages: 16-23
- NAID
  10014370953
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7R^<high>CD4^+ mucosal T cells in mice.2005
- Author(s)
  Okada E, Yamazaki M, Tanabe M, Takeuchi T, Nanno M, Oshima S, Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Hibi T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome2005
- Author(s)
  Namiki S, Kanai T, Watanabe M, et al.
- Journal Title
  
  FEBES Lett 579
  
  Pages: 2781-2787
- Data Source
  KAKENHI-PROJECT-17047014
[Journal Article] Increase of bone maorrow-derived secretory lineage epithelial cells during regeneration in the human intestine2005
- Author(s)
  Matsumoto T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Gastroenterology 128
  
  Pages: 1851-1867
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Regulation of murine chronic colitis by CD4^+CD25^- Programmed Death-1^+ T cells2005
- Author(s)
  Totsuka T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol 18
  
  Pages: 1773-1785
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] IRF-1 mediates upregulation of LMP7 by IFN-gamma and concerted expression of immunosubunits of the proteasome2005
- Author(s)
  Namiki S, Kanai T, Watanabe M, et al.
- Journal Title
  
  FEBES Lett 579
  
  Pages: 2781-2787
- Data Source
  KAKENHI-PROJECT-17590622
[Journal Article] Regulation of murine chronic colitis by CD4^+CD25^- Programmed Death-1^+ T cells2005
- Author(s)
  Totsuka T, Kanai T, Watanabe M, et al.
- Journal Title
  
  Eur J Immunol 18
  
  Pages: 1773-1785
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Th1/Th2-mediated colitis induced by adoptive transfer of CD4^+CD45RB^<high> T lymphocytes into nude mice2005
- Author(s)
  Kanai T, Watanabe M, et al.
- Journal Title
  
  Inflamm Bowel Dis 12
  
  Pages: 89-99
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Human intestinal epithelia-derived IL-18 is a potent prolifrerative factor for intraepithelial lymphocytes synergistically with IL-2, IL-7 and IL-15.2004
- Author(s)
  Okazawa A, Kanai T, Nakamaru T, Sato T, Inoue N, Ogata H, Iwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto R, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T.
- Journal Title
  
  Clin Exp Immunol 136
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Thl mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Kanai T, et al.
- Journal Title
  
  Gut 53
  
  Pages: 1303-1308
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Atsushi Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.
- Journal Title
  
  Gut 53
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.2004
- Author(s)
  Maeda N, Watanabe M, Okamoto S, Kanai T, Yamada T, Hata J, Hozumi N, Katsume A, Nuriya H, Sandhu J, Ishii H, Kohara M, Hibi T.
- Journal Title
  
  Liver Int 24
  
  Pages: 259-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] CD4^+CD25^<bright>FoxP3^+ regulatory T cells in human intestinal lamina propria.2004
- Author(s)
  Makita S, Kanai T, et al.
- Journal Title
  
  J Immunology 173
  
  Pages: 3119-3130
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator and its contribution on amina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IRF-1 and IRF-2 distinctively up-regulate gene expression and production of IL-7 in human intestinal epithelial cells.2004
- Author(s)
  OshimaS, Kanai T, et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6298-6310
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Ectopic CD40 ligand expression on B cells triggers intestinal inflammation.2004
- Author(s)
  Kawamura T, Kanai T, Dohi T, Uraushihara K, Totsuka T, Iiyama R, Taneda C, Yamazaki M, Nakamura T, Aiba Y, Tsubata T, Watanabe M.
- Journal Title
  
  J Immunol 172
  
  Pages: 6388-6397
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively upregulate gene expression and production of interleukin-7 in human intestinal epithelial cells.2004
- Author(s)
  Oshima S, Nakamura T, Kanai T, Handa H, Watanabe M.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6298-6310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] CD4^+CD25^<bright>FoxP3^+ regulatory T cells in human intestinal lamina propria.2004
- Author(s)
  Makita S, Kanai T, et al.
- Journal Title
  
  J Immunol 173
  
  Pages: 3119-3130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Human intestinal epithelia-derived IL-18 is a potent prolifrerative factor or intraepithelial lymphocytes synergistically with IL-2,IL-7 and IL-15.2004
- Author(s)
  Okazawa A, Kanai T, et al.
- Journal Title
  
  Clin Exp Immunol 1362
  
  Pages: 269-276
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] CD4^+CD25^<bright>FoxP3^+ regulatory T cells in human intestinal lamina propria.2004
- Author(s)
  Makita S, Kanai T, Oshima S, Uraushihara K, Totsuka T, Iiyama R, Sawada T, Nakamura T, Koganei K, Fukushima T, Watanabe M.
- Journal Title
  
  J Immunol 173
  
  Pages: 3119-3130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of IL-7 in human intestinal epithelial cells.2004
- Author(s)
  Oshima S, Kanai T, et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6298-6310
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Blockade of B7-H1 suppresses the development of chronic intestinal inflammation.2004
- Author(s)
  Kanai T, et al.
- Journal Title
  
  J Immunol 171
  
  Pages: 4156-4163
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Ectopic CD40 ligand expression on B cells triggers intestinal inflammation.2004
- Author(s)
  Kawamura T, Kanai T, et al.
- Journal Title
  
  J Immunol 172
  
  Pages: 6388-6397
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] The role of inducible co-stimulator (ICOS)/B7 related protein-1 (B7RP-1) interaction in the functional development of Peyer's patches.2003
- Author(s)
  Iiyama R, Kanai T^#, Uraushihara K, Totsuka T, Nakamura T, Miyata T, Yagita H, Kushi A, Suzuki K, Tezuka K, Watanabe M.
- Journal Title
  
  Immunol Letters 88
  
  Pages: 63-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Blockade of B7-H1 suppresses the development of chronic intestinal inflammation.2003
- Author(s)
  Kanai T, Totsuka T, Uraushihara K, Makita S, Nakamura T, Koganei K, Fukushima T, Akiba H, Yagita H, Okumura K, Machida U, Iwai H, Azuma M, Chen L, Watanabe M.
- Journal Title
  
  J Immunol 171
  
  Pages: 4156-4163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Regulation of murine inflammatory bowel disease by CD25^+ and CD25^-CD4^+ Glucocorticoid-induced TNF receptor family-related gene^+ regulatory T cells.2003
- Author(s)
  Uraushihara K^*, Kanai T^<*, #>, Ko K, Totsuka T, Makita S, Iiyama R, Nakamura T, Watanabe M.
- Journal Title
  
  J Immunol 171
  
  Pages: 708-716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis.2003
- Author(s)
  Yamazaki M, Yajima T, Tanabe M, Fukui K, Okada E, Okamoto R, Oshima S, Nakamura T, Kanai T, Takeuchi T, Uehira M, Ishikawa H, Hibi T, Watanabe M.
- Journal Title
  
  J Immunol 171
  
  Pages: 1556-1563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate (DSS) colitis in mice.2003
- Author(s)
  Takagi H, Kanai T, Okazawa A, Kishi Y, Sato T, Takaishi H, Inoue N, Ogata H, Iwao Y, Hoshino K, Takeda K, Akira S, Ishii H, Watanabe M, Hibi T.
- Journal Title
  
  Scan J Gastroenterol 33
  
  Pages: 837-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Morphological and functional abnormalities of Peyer's patch in MyD88-deficient mice.2003
- Author(s)
  Iiyama R, Kanai T, Uraushihara K, Ishikura T, Makita S, Totsuka T, Yamazaki M, Nakamura T, Miyata T, Yoshida H, Takeuchi O, Hoshino K, Takeda K, Ishikawa H, Akira S, Watanabe M.
- Journal Title
  
  Scan J Immunol 58
  
  Pages: 620-627
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003
- Author(s)
  Ezaki, Watanabe M, Inoue N, Kanai T^#, Ogata H, Iwao Y, Ishii H, Hibi T.
- Journal Title
  
  Cancer Res 63
  
  Pages: 3747-3749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Preventive and therapeutic effects of chronic colitis in CD4^+CD45RB^+ T cell-transferred SCID mice by anti-OX40L mAb administration.2003
- Author(s)
  Totsuka T, Kanai T^#, Uraushihara K, Iiyama R, Akiba H, Yagita H, Okumura K, Watanabe M.
- Journal Title
  
  Am J Physiol GI & Liver 284
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Ameliorating effect of anti-ICOS monoclonal antibody in a murine model of chronic colitis.2003
- Author(s)
  Totsuka T, Kanai T^#, Iiyama R, Uraushihara K, Yamazaki M, Okamoto R, Hibi T, Tezuka K, Azuma M, Akiba H, Yagita H, Okumura K, Watanabe M.
- Journal Title
  
  Gastroenterology 124
  
  Pages: 410-421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IL-18 overexpression exacerbates the development of colitis with marked infiltrates macrophages in IL-18 transgenic mice.2003
- Author(s)
  Ishikura T, Kanai T^#, Uraushihara K, Iiyama R, Makita S, Totsuka T, Yamazaki M, Sawada T, Nakamura T, Kitahora T, Hibi T, Hoshino T, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol 18
  
  Pages: 960-969
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator (ICOS) on lamina propria mononuclear cells in rat dextran sulfate sodium (DSS).2003
- Author(s)
  Ishii K, Kanai T, Ishikura T, Totsuka T, Uraushihara K, Yamazaki M, Okamoto R, Araki A, Ohka S, Miyata T, Nakamura T, Kitahora T, Hibi T, Tezuka K, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol 19
  
  Pages: 174-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] The role of cryptopatch-derived intraepithelial lymphocytes in the development of chronic ileocaetitis.2003
- Author(s)
  Makita S, Kanai T, Matsumoto S, Iiyama R, Uraushihara K, Totsuka T, Yamazaki M, Nakamura T, Ishikawa H, Watanabe M.
- Journal Title
  
  Scan J Immunol 58
  
  Pages: 428-435
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Preventive effects of chronic colitis in CD4^+CD45RB^+ T cell-transferred SCID mice by anti-FasL mAb administration.2003
- Author(s)
  Dan N, Kanai T, Totsuka T, Iiyama R, Yamazaki M, Sawada T, Miyata T, Yagita H, Okumura K, Watanabe M.
- Journal Title
  
  Am J Physiol GI & Liver 285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Ameliorating effect of saporin-conjugated anti-CD11b monoclonal antibody in a murine T-cell-mediated chronic colitis.
- Author(s)
  Kanai T^#, Uraushihara K, Totsuka T, Nemoto Y, Fujii R, kawamura T, Makita S, Yagita H, Okumura K, Watanabe M.
- Journal Title
  
  J Gastrornt Hepatol (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.
- Author(s)
  Matsumoto T, Okamoto R, Yagima T, Mori T, Okamoto S, Ikeda Y, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
- Journal Title
  
  Gastroenterology (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Regulation of murine chronic colitis by CD4^+CD25^-Programed Death-1^+ T cells.
- Author(s)
  Totsuka T, Kanai T, Makita S, Fujii R, Nemoto Y, Oshima S, Okamoto R, Koyanagi A, Akiba H, Okumura K, Yagita H, Watanabe M.
- Journal Title
  
  Eur J Immunol (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IRF-inducing proteosomes in human intestinal epithelial cells.
- Author(s)
  Namiki S, Nakamura T, Oshima S, Tsuchiya K, Kanai T, Watanabe M.
- Journal Title
  
  FEBES J (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Presentation] 消化管と他臓器相関2024
- Author(s)
  金井隆典
- Organizer
  日本消化管学会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00425
[Presentation] 腸内細菌を起点とする臓器連関2023
- Author(s)
  金井隆典
- Organizer
  日本医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00425
[Presentation] 自律神経による免疫の制御　腸管-肝臓-脳ネットワークによる腸管恒常性維持機構の解明2022
- Author(s)
  寺谷俊昭, 三上洋平, 金井隆典
- Organizer
  日本自律神経学会総会プログラム
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] 臓器間ネットワークでとらえる内科学　腸内細菌beyond the gut2022
- Author(s)
  金井隆典
- Organizer
  第119回日本内科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] <基礎研究セミナー>　他分野から学ぶメタボエイジング研究の最先端　腸内細菌と腸脳相関2022
- Author(s)
  金井隆典
- Organizer
  日本眼科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] マイクロバイオーム解析による消化器疾患の病態解明と応用　腸内細菌叢解析による寛解期潰瘍性大腸炎の再燃予測の検討2022
- Author(s)
  大野恵子, 三上洋平, 金井隆典
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] 消化管疾患と神経の関わり2022
- Author(s)
  金井隆典
- Organizer
  日本消化管学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] マイクロバイオームの最前線2022
- Author(s)
  金井隆典
- Organizer
  日本女性骨盤底医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] 消化管疾患と神経の関わり2022
- Author(s)
  金井隆典
- Organizer
  日本消化管学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] AIやICTを用いた消化管診療　潰瘍性大腸炎における活動性評価のためのAIを併用した狭帯域光下超拡大内視鏡観察の有用性.2021
- Author(s)
  牟田口真, 細江直樹, 高林馨, 緒方晴彦, 金井隆典.
- Organizer
  第17回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 肝臓－脳－腸管迷走神経反射による腸管制御性T細胞産生機構の解明2021
- Author(s)
  金井隆典
- Organizer
  日本消化器病学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] 腸内細菌情報を受信するLiver-brain-gut神経反射は腸管制御性T細胞を調整する2021
- Author(s)
  金井隆典
- Organizer
  日本自律神経学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] IBDの最新治療新規薬剤登場により何が変わったか　潰瘍性大腸炎におけるTofacitinibとVedolizumabの治療の短期有効性の比較.2020
- Author(s)
  牟田口真, 長沼誠, 金井隆典.
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 腸内細菌情報を統合したLiver-brain-gut神経反射による腸管Treg細胞制御機構の発見.2020
- Author(s)
  金井隆典.
- Organizer
  第48回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性腸疾患に対する内視鏡検査の意義と治療戦略　潰瘍性大腸炎罹患範囲内に発生したSporadic neoplasm診断基準に関する検討.2020
- Author(s)
  高林馨, 岩男泰, 金井隆典.
- Organizer
  第99回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 内視鏡診断が有用であったCampylobacter腸炎併発の難治性潰瘍性大腸炎の一例.2020
- Author(s)
  古島雅子, 清原裕貴, 高林馨, 島田史恵, 春日良介, 三上洋平, 河口貴昭, 南木康作, 筋野智久, 牟田口真, 細江直樹, 緒方晴彦, 金井隆典.
- Organizer
  第361回日本消化器病学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 内視鏡による炎症性腸疾患診療の進歩　走査電子顕微鏡で観察された潰瘍性大腸炎患者の粘膜表面構造.2020
- Author(s)
  種本俊, 筋野智久, 野村絵奈, 細江直樹, 金井隆典.
- Organizer
  第111回日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 腸内細菌による免疫・神経反射の臓器連関破綻によるヒト消化器免疫疾患の病態の解明2020
- Author(s)
  金井隆典
- Organizer
  第49回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H00536
[Presentation] Translational researchを目指した下部消化管研究　潰瘍性大腸炎大腸粘膜における炎症関連遺伝子の体細胞突然変異と、炎症・発がんへの関連.2020
- Author(s)
  南木康作, 佐藤俊朗, 金井隆典.
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 生薬『青黛』による潰瘍性大腸炎患者における寛解維持効果の検討と腸内細菌叢の解析.2020
- Author(s)
  吉松裕介, 筋野智久, 福田知広, 長沼誠, 金井隆典.
- Organizer
  第118回日本内科学会総会・講演会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 臓器間ネットワークと肝疾患　小腸-脂肪組織-肝臓の臓器間ネットワークを介したNAFLD制御の可能性.2020
- Author(s)
  中本伸宏,ちょ柏松, 金井隆典.
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 小腸内視鏡診療の現状と展望　小腸狭窄を有するCrohn病患者におけるバルーン拡張術の必要性に関する検討.2020
- Author(s)
  林由紀恵, 高林馨, 細江直樹, 緒方晴彦, 金井隆典.
- Organizer
  第111回消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 発赤領域として発見されESDにより確定診断されたUC関連平坦型dysplasiaの1例.2020
- Author(s)
  萩原裕也, 岩男泰, 牟田口真, 杉本真也, 南木康作, 三上洋平, 筋野智久, 前畑忠輝, 矢作直久, 下田将之, 長沼誠, 緒方晴彦, 金井隆典.
- Organizer
  第38回日本大腸検査学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 難治性潰瘍性大腸炎に対するシクロスポリン持続静注療法の使用意義.2020
- Author(s)
  青木康浩, 福田知広, 吉松裕介, 南木康作, 三上洋平, 福原佳代子, 牟田口真, 筋野智久, 高林馨, 井上詠, 緒方晴彦, 岩男泰, 長沼誠, 金井隆典.
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 消化器疾患における最先端のトランスレーショナルリサーチ　オルガノイドによる解析で判明した潰瘍性大腸炎患者の腸管上皮における炎症耐性変異の蓄積.2020
- Author(s)
  南木康作, 金井隆典, 佐藤俊朗.
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] バルーン内視鏡による診断・治療の進歩　バルーン内視鏡によるクローン病の深部小腸病変評価の意義.2020
- Author(s)
  高林馨, 細江直樹, 長沼誠, 緒方晴彦, 金井隆典.
- Organizer
  第110回日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 原発性硬化性胆管炎の病態に寄与する腸内細菌.2020
- Author(s)
  中本伸宏,ちょ柏松, 金井隆典.
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性腸疾患におけるLRGとアダリムマブ血中濃度の関係　Planet studyサブ解析.2020
- Author(s)
  梁井俊一, 新崎信一郎, 松岡克善, 水野慎大, 飯島英樹, 仲哲治, 金井隆典.
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性腸疾患に対する血球成分除去療法の新たな展開　難治性潰瘍性大腸炎患者に対するCAPの維持効果と安全性.2020
- Author(s)
  横山陽子, 長沼誠, 渡辺憲治, 金井隆典.
- Organizer
  第41回日本アフェレシス学会学術大会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性疾患における最先端の内視鏡診療-IBD関連腫瘍の診断と治療　潰瘍性大腸炎罹患範囲内の腫瘍性病変に対するESD施行例の検討.2020
- Author(s)
  牟田口真, 岩男泰, 金井隆典.
- Organizer
  第28回日本消化器関連学会週間
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] AIを用いた次世代の内視鏡診療　潰瘍性大腸炎における活動性評価のためのAIを併用した超拡大内視鏡の有用性.2020
- Author(s)
  牟田口真, 緒方晴彦, 金井隆典.
- Organizer
  第99回日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性腸疾患診療における内視鏡の役割　潰瘍性大腸炎に対してVedolizumab治療症例における内視鏡の役割.2020
- Author(s)
  牟田口真, 長沼誠, 福田知広, 緒方晴彦, 金井隆典.
- Organizer
  第110回日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 消化器疾患における共生微生物叢研究の新たな知見　潰瘍性大腸炎患者における5-ASA製剤不耐には腸内細菌叢の変化が関与している.2020
- Author(s)
  三上洋平, 水野慎大, 金井隆典.
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 腸内細菌と肝臓疾患.2020
- Author(s)
  中本伸宏, 金井隆典.
- Organizer
  第48回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 診断的EMRによって診断し得た偽性アカラシアの一例.2020
- Author(s)
  窪澤陽子, 正岡建洋, 猪口和美, 高取裕作, 福原誠一郎, 加藤元彦, 辻川華子, 金井隆典.
- Organizer
  第111回日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 腸内細菌と消化器疾患2019
- Author(s)
  金井隆典
- Organizer
  日本内科学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 症性腸疾患診療のリアルワールド～生物学的製剤に対するクリニカルクエスチョンを解決する　実臨床におけるクローン病に対するウステキヌマブの有効性・安全性に関する検討2019
- Author(s)
  福田知広, 長沼誠, 金井隆典.
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 食と免疫　潰瘍性大腸炎への応用.2019
- Author(s)
  金井隆典
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] .粘膜治癒を目指す潰瘍性大腸炎治療の現状と未来2019
- Author(s)
  金井隆典.
- Organizer
  日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 微生物叢から見た消化管病態の新知見2019
- Author(s)
  金井隆典
- Organizer
  日本消化管学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 潰瘍性大腸炎の粘膜治癒観察から2019
- Author(s)
  金井隆典
- Organizer
  日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] Mayo内視鏡スコア1の潰瘍性大腸炎患者におけるインフリキシマブ使用の有無による再燃リスクの違いに関する検討.2019
- Author(s)
  福田知広, 長沼誠, 金井隆典.
- Organizer
  日本消化器内視鏡学会総会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 腸内細菌叢を応用した臨床研究2019
- Author(s)
  金井隆典
- Organizer
  日本無菌生物ノートバイオロジー学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 炎症性腸疾患における疾患活動性マーカーとしてのLRGの意義2019
- Author(s)
  仲哲治, 新崎信一郎, 松岡克善, 水野慎大, 飯島英樹, 金井隆典, 松本主之
- Organizer
  日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 消化器領域における腸内細菌研究と臨床応用　青黛により誘導される腸内細菌叢の潰瘍性大腸炎への治療応用2019
- Author(s)
  吉松裕介, 筋野智久, 金井隆典
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 広範な潰瘍性病変を呈したアメーバ性大腸炎の一例.2019
- Author(s)
  津軽開, 高林馨, 南木康作, 野田まりん, 下嵜啓太郎, 林由紀恵, 平田賢郎, 福原佳代子, 三上洋平, 水野慎大, 加藤元彦, 正岡建洋, 細江直樹, 長沼誠, 緒方晴彦, 金井隆典
- Organizer
  日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] IBD関連腫瘍の診断および治療の現状と展望　潰瘍性大腸炎関連腫瘍に対する内視鏡治療例の検討2019
- Author(s)
  萩原裕也, 岩男泰, 長沼誠, 矢作直久, 金井隆典
- Organizer
  日本消化器内視鏡学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 潰瘍性大腸炎患者に対する青黛の現状の位置付け2019
- Author(s)
  杉本真也, 長沼誠, 福田知広, 南木康作, 水野慎大, 木村佳代子, 高林馨, 井上詠, 緒方晴彦, 岩男泰, 金井隆典
- Organizer
  日本消化管学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 原発性硬化性胆管炎における病因腸内細菌の関与2019
- Author(s)
  金井隆典, 中本伸宏
- Organizer
  日本臨床免疫学会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 原発性硬化性胆管炎に関連する腸内細菌の探索.2019
- Author(s)
  金井隆典
- Organizer
  日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] ニボルマブ投与中に急性腸炎を発症した一例2019
- Author(s)
  佐藤萌, 脇坂悠介, 津軽開, 平田賢郎, 三上洋平, 水野慎大, 筋野智久, 須河恭敬, 浜本康夫, 高石官均, 長沼誠, 金井隆典, 前原純樹
- Organizer
  日本消化器病学会関東支部例会
- Data Source
  KAKENHI-PROJECT-18KK0246
[Presentation] 原発性硬化性胆管炎の病態における腸内細菌の関与2017
- Author(s)
  中本伸宏，谷木信仁，金井隆典
- Organizer
  第59回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 腸内細菌，腸管粘膜バリアの修飾を介した肝臓内免疫応答・免疫寛容誘導機序2017
- Author(s)
  中本伸宏，谷木信仁，金井隆典
- Organizer
  第103回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] gut-liver-brain axis によるマウス大腸炎抑制制御メカニズム2016
- Author(s)
  寺谷俊昭, 中本伸宏, 千葉明子, 鈴木貴博, 水野慎大, 長沼誠, 金井隆典
- Organizer
  第 53 回日本消化器免疫学会総会
- Place of Presentation
  ホテルニューオータニ大阪　大阪府大阪市
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] gut-liver-brain axis によるマウス大腸炎抑制制御メカニズム2016
- Author(s)
  寺谷俊昭, 中本伸宏, 千葉明子, 鈴木貴博, 水野慎大, 長沼誠, 金井隆典
- Organizer
  第 53 回日本消化器免疫学会総会
- Place of Presentation
  ホテルニューオータニ大阪　大阪府大阪市
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 難治性消化管疾患に対する糞便微生物移植法の経過報告2016
- Author(s)
  水野慎大，正岡建洋，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 治療抵抗性・難治性潰瘍性大腸炎に対する青黛の有用性2016
- Author(s)
  福田知広，長沼　誠，金井隆典
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] エンドサイトを用いた潰瘍性大腸炎内視鏡的寛解例における組織学的活動度評価の意義2016
- Author(s)
  中里圭宏，長沼誠，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 腸内細菌を標的にした疾患治療2016
- Author(s)
  金井隆典
- Organizer
  第44回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 難治性消化管疾患に対する糞便微生物移植法の経過報告2016
- Author(s)
  水野慎大，正岡建洋，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] カプセル化した青黛の潰瘍性大腸炎の寛解導入における有用性2016
- Author(s)
  杉本真也，長沼誠，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] カプセル化した青黛の潰瘍性大腸炎の寛解導入における有用性2016
- Author(s)
  杉本真也，長沼誠，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 炎症性腸疾患に対する外来ステロイド療法の有用性2016
- Author(s)
  牟田口真，長沼誠，金井隆
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 新専門医制度に向けた大腸肛門病専門医研修プログラム作成―内科系から見た現状と課題2016
- Author(s)
  井上詠，岩男泰，長沼誠，緒方晴彦，金井隆典
- Organizer
  第71回日本大腸肛門病学会学術集会
- Place of Presentation
  三重県営サンアリーナ（三重県）
- Year and Date
  2016-11-18
- Data Source
  KAKENHI-PROJECT-15K08974
[Presentation] 治療抵抗性・難治性潰瘍性大腸炎に対する青黛の有用性2016
- Author(s)
  福田知広，長沼　誠，金井隆典
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] エンドサイトを用いた潰瘍性大腸炎内視鏡的寛解例における組織学的活動度評価の意義2016
- Author(s)
  中里圭宏，長沼誠，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 炎症性腸疾患に対する外来ステロイド療法の有用性2016
- Author(s)
  牟田口真，長沼誠，金井隆典
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 腸管上皮オルガノイドを用いた幹細胞移植技術の確立2016
- Author(s)
  杉本真也，金井隆典，佐藤俊朗
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 内視鏡的活動期の潰瘍性大腸炎に対する治療介入が臨床経過と粘膜治癒に与える影響2016
- Author(s)
  大野恵子，長沼　誠，金井隆典
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 腸疾患における糞便微生物移植法の現状と将来2016
- Author(s)
  金井隆典
- Organizer
  日本大腸肛門病学会
- Place of Presentation
  三重県営サンアリーナ　三重県津市
- Invited
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 潰瘍性大腸炎術後吻合部の瘻孔に対しインフリキシマブが著効した1例2016
- Author(s)
  大野恵子, 長沼誠, 新井万里, 清原裕貴, 杉本真也, 南木康作, 水野慎大, 牟田口真, 中里圭宏, 別所理恵子, 井上詠, 岩男泰, 緒方晴彦, 金井隆典
- Organizer
  第102回日本消化器内視鏡学会関東支部例会
- Place of Presentation
  シェーンバッハ・サボー（東京都千代田区）
- Year and Date
  2016-06-11
- Data Source
  KAKENHI-PROJECT-15K08974
[Presentation] 大腸疾患における糞便微生物移植法の現状と将来2016
- Author(s)
  金井隆典
- Organizer
  日本大腸肛門病学会
- Place of Presentation
  三重県営サンアリーナ　三重県津市
- Invited
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 腸管上皮オルガノイドを用いた幹細胞移植技術の確立2016
- Author(s)
  杉本真也，金井隆典，佐藤俊朗
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 内視鏡的活動期の潰瘍性大腸炎に対する治療介入が臨床経過と粘膜治癒に与える影響2016
- Author(s)
  大野恵子，長沼　誠，金井隆典
- Organizer
  第58回日本消化器病学会
- Place of Presentation
  神戸コンベンションセンター　兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 腸内細菌を標的にした疾患治療2016
- Author(s)
  金井隆典
- Organizer
  第44回日本臨床免疫学会総会
- Place of Presentation
  京王プラザホテル　東京都新宿区
- Invited
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] SLCO2A1発現解析を用いた非特異性多発性小腸潰瘍症の診断と病態解明へアプローチ2016
- Author(s)
  久松理一，島村克好，細江直樹，杉浦悠毅，高橋信一，金井隆典
- Organizer
  第12回日本消化管学会総会学術集会
- Place of Presentation
  東京京王プラザホテル
- Year and Date
  2016-02-26
- Data Source
  KAKENHI-PROJECT-15H04811
[Presentation] 潰瘍性大腸炎患者に対する大腸カプセル内視鏡前処置の工夫（クエン酸モサプリドの効果）2015
- Author(s)
  細江直樹、宮永亮一、三枝慶一郎、小林拓、中野雅、長沼誠、日比紀文、金井隆典、緒方晴彦
- Organizer
  第8回日本カプセル内視鏡学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-15
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 非特異性多発性小腸潰瘍症の診断における内視鏡下生検の意味2015
- Author(s)
  久松理一、細江直樹、金井隆典
- Organizer
  第89回日本消化器内視鏡学会
- Place of Presentation
  名古屋国際会議場愛知県名古屋市
- Year and Date
  2015-05-31
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] New drug development for inflammatory bowel disease in Japan: an example of collaboration among academia, industry, and government.2015
- Author(s)
  Katsuyoshi Matsuoka, Makoto Naganuma, Takanori Kanai
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター　宮城県仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] New drug development for inflammatory bowel disease in Japan: an example of collaboration among academia, industry, and government.2015
- Author(s)
  Katsuyoshi Matsuoka, Makoto Naganuma, Takanori Kanai
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター宮城県仙台市
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] クローン病生物学的製剤2次無効例に対する画像評価の有用性2015
- Author(s)
  中里圭宏、長沼誠、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター宮城県仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] クローン病生物学的製剤2次無効例に対する画像評価の有用性2015
- Author(s)
  中里圭宏、長沼誠、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター　宮城県仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 非特異性多発性小腸潰瘍症の診断における内視鏡下生検の意味ワークショップ7　希少難治性消化管疾患における内視鏡の役割2015
- Author(s)
  久松理一，細江直樹，金井隆典
- Organizer
  第89回日本消化器内視鏡病学会総会
- Place of Presentation
  名古屋
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15H04811
[Presentation] 質量分析法を用いたNSAIDs起因性小腸潰瘍の小腸粘膜PG代謝物の網羅的解析による病態解明と今後の展望2015
- Author(s)
  久松理一，島村克好，金井隆典，高橋信一，杉浦悠毅
- Organizer
  第53回小腸研究会
- Place of Presentation
  盛岡
- Year and Date
  2015-11-07
- Data Source
  KAKENHI-PROJECT-15H04811
[Presentation] 小腸pyogenic granuloma4例の臨床的検討．2015
- Author(s)
  宮永亮一、細江直樹、平田賢郎、中里圭宏、長沼誠、岩男泰、緒方晴彦、金井隆典
- Organizer
  第101回日本消化器内視鏡学会関東支部例会
- Place of Presentation
  シェーンバッハ・サボー(東京都千代田区)
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-15K08974
[Presentation] SLOCO2A1変異によるPG輸送障害と非特異性多発性小腸潰瘍症2015
- Author(s)
  久松理一，細江直樹，金井隆典
- Organizer
  第101回日本消化器病学会総会
- Place of Presentation
  仙台
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H04811
[Presentation] 炎症性腸疾患における腸内細菌の関与2015
- Author(s)
  水野慎大、南木康作、長沼誠、金井隆典
- Organizer
  第43回日本臨床免疫学会総会
- Place of Presentation
  神戸国際会議場兵庫県神戸市
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] ワークショップ4「小腸疾患：病態解明への新たな知見」2015
- Author(s)
  久松理一、細江直樹、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター宮城県仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 炎症性腸疾患における腸内細菌の関与2015
- Author(s)
  水野慎大、南木康作、長沼誠、金井隆典
- Organizer
  第43回日本臨床免疫学会総会
- Place of Presentation
  神戸国際会議場兵庫県神戸市
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 潰瘍性大腸炎合併大腸癌初期病変の内視鏡像の検討2015
- Author(s)
  長沼誠，岩男泰，金井隆典
- Organizer
  第89回日本消化器内視鏡学会総会
- Place of Presentation
  名古屋国際会議場(愛知県名古屋市)
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-15K08974
[Presentation] 潰瘍性大腸炎合併大腸癌・dysplasiaの内視鏡的危険因子の検討2015
- Author(s)
  金井隆典、長沼誠、岩男泰
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター宮城県仙台市
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] 潰瘍性大腸炎患者におけるサイトメガロウイルス活性化に対しての抗ウイルス療法の必要性の検討2015
- Author(s)
  南木康作、武内悠里子、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター宮城県仙台市
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15H02534
[Presentation] ワークショップ4「小腸疾患：病態解明への新たな知見」2015
- Author(s)
  久松理一、細江直樹、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター　宮城県仙台市
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 肝臓内免疫寛容誘導に寄与する腸内細菌叢の検討2015
- Author(s)
  山口晃弘、海老沼浩利、網谷、林、褚柏松、谷木、山口、志波俊輔、長沼誠、齋藤、金井隆典
- Organizer
  第52回日本消化器免疫学会総会
- Place of Presentation
  京王プラザホテル東京都新宿区
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 潰瘍性大腸炎患者におけるサイトメガロウイルス活性化に対しての抗ウイルス療法の必要性の検討2015
- Author(s)
  南木康作、武内悠里子、金井隆典
- Organizer
  第101回日本消化器病学会
- Place of Presentation
  仙台国際センター　宮城県仙台市
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15K15298
[Presentation] 潰瘍性大腸炎患者に対するクエン酸モサプリドを用いた大腸カプセル内視鏡前処置法2014
- Author(s)
  細江直樹、中野雅、南木康作、三枝慶一郎、碓井真吾、筋野智久、小林拓、松岡克善、長沼誠、久松理一、井上詠、芹澤宏、日比紀文、金井隆典、緒方晴彦
- Organizer
  第32回　日本大腸検査学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] "シンポジウム3　難治性小腸疾患に対する治療の工夫2014
- Author(s)
  久松理一，島村克好，細江直樹,　緒方晴彦，小崎健次郎，梅野淳嗣，松本主之，金井隆典
- Organizer
  第52回小腸研究会
- Place of Presentation
  東京ガーデンパレス(東京都文京区）
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-24390190
[Presentation] 早期クローン病に対するアダリムマブ治療効果　－アダリムマブ有効性の高い患者背景－2014
- Author(s)
  南木康作，三好　潤，大野恵子，新井万里，清原裕貴，杉本真也，森　清人，三枝慶一郎，武下達矢，竹下　梢，中里圭宏，長沼　誠，矢島知治，久松理一, 金井隆典
- Organizer
  第6回日本炎症性腸疾患研究会学術集会
- Place of Presentation
  TKP品川ガーデンシティ品川（東京都港区）
- Year and Date
  2014-12-14
- Data Source
  KAKENHI-PROJECT-24390190
[Presentation] "シンポジウム1　小腸疾患の見つけ方と診断・治療のストラテジー2014
- Author(s)
  長沼　誠，奥田茂男，久松理一，金井隆典，緒方晴彦
- Organizer
  第52回小腸研究会
- Place of Presentation
  東京ガーデンパレス(東京都文京区）
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-24390190
[Presentation] Clostridium Butyricum Regulates IL-10 Production in Normal and Inflammatory Conditions Through Different Target Cells2013
- Author(s)
  Hayashi A, Kanai T, Sato T, Mikami Y, Matsuoka K, Hisamatsu T, Yoshimura A, Kamada N, Yagita H, Hibi T.
- Organizer
  Digestive Disease Week 2013
- Place of Presentation
  Orlando, USA
- Year and Date
  2013-05-19
- Data Source
  KAKENHI-PROJECT-24659375
[Presentation] Colitogenic Th17 Cells may Help the Generation of Colitogenic RORγt-Independent ClassicalTh1 Cells2013
- Author(s)
  Saigusa K, Kanai T, Sujino T, Handa T, Hayashi A, Mikami Y,Mizuno S, Matsumoto A, Matuoka Y, Sato T, Hisamatsu T, Hibi T.
- Organizer
  16th International Congress of Mucosal Immunology
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2013-07-17
- Data Source
  KAKENHI-PROJECT-24659375
[Presentation] 腸管におけるRorgt依存的lnnate Lymphoid cells(lLCs)の機能解析及び炎症制御能の解明2012
- Author(s)
  木村佳代子、金井隆典、林篤史、筋野智久、三上洋平、半田一己、松岡克善、佐藤俊朗、久松理一、日比紀文
- Organizer
  第49回日本消化器病学会総会
- Place of Presentation
  鹿児島
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PROJECT-24659375
[Presentation] Complete mucosal healing is associated with long-term remission in ulcerative colitis.2012
- Author(s)
  Inoue N, Takabayashi K, Matsuoka K, Hisamatsu T, Kanai T, Ogata H, Iwao Y, Hibi T.
- Organizer
  Digestive Disease Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23590949
[Presentation] Novel technique of endoscopic submucosal dissection using external forceps for early rectal cancer.2012
- Author(s)
  Imaeda H, Hosoe N, Ida Y, Nakamizo H, Kashiwagi H, Kanai T, Iwao Y, Hibi T, Ogata H.
- Organizer
  The 14th Meeting of International Conference on Ulcer Research.
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23590949
[Presentation] Anti-viral therapy is not necessarily indicated in ulcerative colitis patients with cytomegalovirus infection detected by immunohistochemistry.2012
- Author(s)
  Maruyama Y, Matsuoka K, Iwao Y, Yajima T, Inoue N, Hisamatsu T, Sujino T, Takabayashi K, Yoneno K, Mikami Y, Miyoshi J, Mizuno S, Kimura K, Kanai T, Ogata H, Mukai M, Hibi T.
- Organizer
  Digestive Disease Week 2012
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23590949
[Presentation] Early normalization of C-reactive protein (CRP)by infliximab is a predictive factor of sustained long-term clinical efficacy in crohn’s disease.2012
- Author(s)
  Kimura K, Matsuoka K, Kanai T, Okamoto S, Hisamatsu T, Inoue N, Yajima T, Ogata H, Iwao Y, Hibi T.
- Organizer
  The 14th Meeting of International Conference on Ulcer Research
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-23590949
[Presentation] Feasibility of Evaluating the Mucosal Inflammation in Ulcerative Colitis by Using a Second Generation Colon Capsule Endoscope.2012
- Author(s)
  Hosoe N, Matsuoka K, Naganuma M, Ishibashi Y, Kimura K, Yoneno K, Usui S, Kashiwagi K, Hisamatsu T, Inoue N, Kanai T, Imaeda H, Hibi T, Ogata H
- Organizer
  Asian Pacific Digestive Week 2012
- Place of Presentation
  Bangkok
- Data Source
  KAKENHI-PROJECT-22590763
[Presentation] A case report of infliximab use in pregnant UC patient exacerbating with a complication of CMV colitis.2012
- Author(s)
  Tsukagoshi U, Saigusa K, Yajima T, Hisamatsu T , Matuoka K, Naganuma M, Inoue　N, Kanai T, Ogata H, Iwao Y, Hibi T.
- Organizer
  Asian IBD Symposium Seoul 2012
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23590949
[Presentation] 炎症性腸疾患と健常にそれぞれ存在する腸管Th17細胞の決定的な相違の追求2012
- Author(s)
  金井隆典、筋野智久、三上洋平、日比紀文
- Organizer
  第40回日本臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2012-09-27
- Data Source
  KAKENHI-PROJECT-24659375
[Presentation] わが国の炎症性腸疾患の疫学、病因、病態の最新情報2011
- Author(s)
  金井隆典
- Organizer
  第140回日本医学会シンポジウム
- Place of Presentation
  東京(日本医師会館)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] 腸管慢性炎症性疾患におけるTreg、Th17、Th17/Th1、Th1細胞の産生誘導、競合性、可塑性に関する総括的検討2011
- Author(s)
  金井隆典
- Organizer
  第39回日本臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] In vivo visualization and evaluation of colorectal inflammation in ulceretivecolitis by a newly integrated endocytoscopy.2011
- Author(s)
  Kimura K, Kanai T, Bessho R, Hosoe N, Kobayashi T, Takayama T, Inoue N, Mukai M, Ogata H, and Hibi T
- Organizer
  Digestive Disease Week2011
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22590763
[Presentation] 潰瘍性大腸炎の治療戦略～これまでの10年とこれからの10年～2011
- Author(s)
  金井隆典
- Organizer
  JDDW2011福岡サテライトシンポジウム
- Place of Presentation
  福岡(福岡国際会議場)
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PUBLICLY-22021038
[Presentation] 腸管慢性炎症性疾患におけるTreg、Th17、Th17/Th1、Th1細胞の産生誘導、競合性、可塑性に関する総括的検討2011
- Author(s)
  金井隆典
- Organizer
  第39回日本臨床免疫学会総会合同シンポジウム
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2011-09-16
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] わが国の炎症性腸疾患の疫学、病因、病態の最新情報2011
- Author(s)
  金井隆典
- Organizer
  第140回日本医学会
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Oral tacrolimus therapy is useful for patients with intractable ulcerative colitis : A result of post-marketing analysis2011
- Author(s)
  Inoue N, Ichikawa R, Miyoshi J, Matsuoka K, Hisamatsu T, Okamoto S, Ogata H, Iwao Y, Kanai T, Hibi T
- Organizer
  15th International Congress of Mucosal Immunology
- Place of Presentation
  Paris France
- Data Source
  KAKENHI-PROJECT-22590763
[Presentation] 炎症性腸疾患の病態解明-ヒト病変粘膜の解析からのアプローチ-2011
- Author(s)
  久松理一、金井隆典、日比紀文
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京(京王プラザホテル)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PUBLICLY-22021038
[Presentation] 免疫記憶と免疫加齢からみたIBD粘膜免疫の病態-小児IBDへのヒント2011
- Author(s)
  金井隆典
- Organizer
  第38回日本小児栄養消化器内科肝臓学会
- Place of Presentation
  岩手県
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] 免疫記憶と免疫加齢からみた工BD粘膜免疫の病態-小児IBDへのヒント2011
- Author(s)
  金井隆典
- Organizer
  第38回日本小児栄養消化器内科肝臓学会
- Place of Presentation
  岩手県(ホテル紫苑)
- Year and Date
  2011-10-08
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Real-time in vivo diagnosis of trophozoites in patients with amoebic colitis using newly developed endocytoscope.2010
- Author(s)
  Hosoe N, Kobayashi T, Kanai T, Bessho R, Takayama T, Inoue N, Imaeda H, Ogata H, and Hibi T
- Organizer
  18th United European Gastroenterology Week
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-22590763
[Presentation] 血漿アミノ酸プロファイルを用いた炎症性腸疾患の診断・活動性モニタリング2010
- Author(s)
  久松理一、井上詠、松岡克善、斉藤理子、筋野智久、米野和明、三好潤、三上洋平、岩男泰、緒方晴彦、金井隆典、日比紀文、安藤朗、藤山佳秀、内山和彦、高木智久、内藤裕二、吉川敏一
- Organizer
  難治性腸管障害調査研究班
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 炎症性腸疾患における生物学的製剤による治療法の進歩Infliximab計画的維持投与クローン病症例からみた長期治療効果の検討2010
- Author(s)
  金井隆典、松岡克義、岡本晋
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PUBLICLY-22021038
[Presentation] Long-term prognosis of ulcerative colitis patients treated with cytoapheresis therapy2010
- Author(s)
  Takayama T, Okamoto S, Naganuma M, Saito R, Sujino T, Mikami T, Inoue N, Hisamatsu T, Yajima T, Matsuoka K, Ogata H, Kanai T, Iwao Y and Hibi T
- Organizer
  5th Japan-Korea IBD Symposium
- Place of Presentation
  Seoul
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-22590763
[Presentation] 炎症性腸疾患における生物学的製剤による治療法の進歩Infliximab計画的維持投与クローン病症例からみた長期治療効果の検討2010
- Author(s)
  金井隆典、松岡克義、岡本晋
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2010-10-05
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  Intemational Congress of Mucosal Immunology
- Place of Presentation
  ボストン
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] 腸肉細菌から直接的自然免疲と抗原刺激を受ける炎症性腸挟患メモリ-C04+T細胞の維持機構2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells can be Maintained Out side the Intestine in the Absence of Commesal Bacteria2009
- Author(s)
  根本泰宏, 金井隆典, 松本敏, 渡辺守
- Organizer
  Japan & US Collaboration Conference in Gastroenterology
- Place of Presentation
  東京
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells can be Maintained Outside the Intestine in the Absence of Commesal Bacteria2009
- Author(s)
  根本泰宏、金井隆典、松本敏、渡辺守
- Organizer
  Japan & US Collaboration Conference in Gastroenterology
- Place of Presentation
  東京
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] 腸内細菌から直接的自然免疫と抗原刺激を受ける炎症性腸疾患メモリ―CD4+T細胞の維持機構2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守
- Organizer
  日本消化器病学会パネルディスカッション
- Place of Presentation
  東京
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] 炎症性腸疾患治療標的としてのIL-7高産生細胞の同定2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  日本消化器免疫学会総会シンポジウム
- Place of Presentation
  松山市
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] Long-lived Colitogenic CD4+ Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  ボストン
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] 炎症性腸疾患治療標的としてのIL-7高産生細胞の同定2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  日本消化器免疲学会総会
- Place of Presentation
  松山市
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Long-lived Colitogenic C04+Memory T Cells Residing Outside the Intestine Participate in the Perpetuation of Chronic Colitis2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  International Congress of Mucosal Immunology
- Place of Presentation
  ボストン
- Year and Date
  2009-07-07
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Long-lived Colitogenic C04+Memory T Cells can be Maintained Outside the Intestine in the Absence of Commesal Bacteria2009
- Author(s)
  根本泰宏、金井隆典、松本敏、渡辺守
- Organizer
  Japan & US Collaboration Conference
- Place of Presentation
  東京
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] 腸内細菌から直接的自然免疫と抗原刺激を受ける炎症性腸疾患メモリ-CD4+T細胞の維持機構2009
- Author(s)
  根本泰宏、金井隆典、渡辺守
- Organizer
  日本消化器病学会パネルディスカッション
- Place of Presentation
  東京
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] 炎症性腸疾患治療標的としてのIL-7高産生細胞の同定2009
- Author(s)
  根本泰宏, 金井隆典, 渡辺守
- Organizer
  日本消化器免疫学会総会シンポジウム
- Place of Presentation
  松山市
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-21390233
[Presentation] Negatibe feedback regulation of pathogenic CD4IT Cells by increased granulopoiesis2008
- Author(s)
  Nemoto T, Y, Kanai T, Tohda S, Tptsuka T, Okamoto R, Isuchiya K, Fukuda T, Yagita H, and Watanabe M
- Organizer
  109^<th>Annual meeting of the AGA Tnstitute
- Place of Presentation
  San Diego, CA
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] Negatibe feedback regulation of pathogenic CD4+T Cells by increased granulopoiesis.2008
- Author(s)
  Nemoto T, Y, Kanai T, Tohda S, Tptsuka T Okamoto R, Tsuchiya K, Fukuda T, Yagita H, Watanabe M.
- Organizer
  109^<th> Annual meeting of the AGA Institute
- Place of Presentation
  San Doego, CA
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19390197
[Presentation] Negatibe feedback regulation of pathogenic CD4+T Cells by increased granulopoiesis2008
- Author(s)
  Nemoto T, Kanai T, Tohda S, Tptsuka T, Okamoto R, TsuchiyaK, Fukuda T, Yagita H, and Watanabe M.
- Organizer
  109^<th> Annual meeting of the AGA Institute
- Place of Presentation
  San Doego, CA
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19390197
[Presentation] Colitogenic CD4+ T Cells convert to regulatory cells to suppress colitis in the process of the immunosenescence.2008
- Author(s)
  Totsuka T, Kanai T Nemoto Y, Tomita T, Watanabe M
- Organizer
  DDW 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] IL-17を標的とした腸炎惹起性メモリ-T細胞の制御2008
- Author(s)
  根本康宏、金井隆典、渡辺守
- Organizer
  第50回日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20060010
[Presentation] Dysregulated differentiation of intestinal epithelia in UC2008
- Author(s)
  Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Watanabe M
- Organizer
  3rd Japan-Korea IBD Symposium
- Place of Presentation
  Korea(Seoul)
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] IL-17を標的とした腸炎惹起性メモリーT細胞の制御2008
- Author(s)
  根本康宏、金井隆典、渡辺守
- Organizer
  第50回日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-19390197
[Presentation] Colitogenic CD4+ T Cells convert to regulatory cells to suppress colitis in the process of the immunosenescence2008
- Author(s)
  Totsuka T, Kanai T Nemoto Y, Tomita T, Watanabe M
- Organizer
  DDW 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Notch signaling suppresses the transcriptional activity of Hath1 Gene, resulting in the undifferentiated form of human intestinal epithelial cells2008
- Author(s)
  Tsuchiya K, Inoue K, Aragaki M, Okamoto R, Nakamura T, Kanai T, Watanabe M
- Organizer
  DDW 2008
- Place of Presentation
  San Diego
- Year and Date
  2008-05-20
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] Uniqueness of colitogenic lamina propria CD4+ T cells for the perpetuation of colitis.2007
- Author(s)
  Kanai T, Nemoto Y, et. al.
- Organizer
  ICMI2007
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18659204
[Presentation] Uniqueness of colitogenic lamina propria CD4+ T cells for the perpetuation of colitis.2007
- Author(s)
  Kanai T, Nemoto Y, et. al.
- Organizer
  ICMI2007
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19390197
[Presentation] Continuous recirculation of colitogenic CD4+ T cells may be required for perpetuation of chronic colitis2007
- Author(s)
  Tomita T, Kanai T, Fujii Y, Nemoto Y, Makita S, Totsuka T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington.D.C
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Bone marrow retaining colitogenic CD4+ T cells may be a pathogenic reservoir for chronic colitis2007
- Author(s)
  Nemoto Y, Kanai T, Makita S, Okamoto R, Totsuka T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington.D.C
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Uniqueness of colitogenic lamina propria CD4+ T cells for the perpetuation of colitis2007
- Author(s)
  Kanai T, Nemoto Y, Shinohara T, Fujii T, Ito Y, Tomita T, Okamoto R, Tsuchiya K, Totsuka T, Watanabe M
- Organizer
  ICMI2007
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Bone marrow is a reservoir for persistent colitogenic CD + TEM cells in IL-7 dependent manner2007
- Author(s)
  Nemoto Y, Kanai T, Makita S, Totsuka T, Watanabe M
- Organizer
  ICMI2007
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Systemic, but not intestinal, IL-7 is essential for the persistence of chronic colitis2007
- Author(s)
  Tomita T, Kanai T, Nemoto Y, Fujii T,Shinohara T, Kameyama K, Totsuka T, Watanabe M
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Stabilization of Atoh1 protein induces Mucin2 gene expression in human colon cancer cells2007
- Author(s)
  Tsuchiya K, Okamoto R, Kanai T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington, D.C.
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] Blockade of TNF-α inhibits tumor progression in colitis-associated cancer2007
- Author(s)
  Onizawa M, Kanai T, Nemoto Y, OshimaS, Makita S, Okamoto R, Totsuka T, YagitaH, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington, D.C.
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] Blockade of TNF-α inhibits tumor progression in colitis-associated cancer2007
- Author(s)
  Onizawa M, Kanai T, Nemoto Y, Oshima S, Makita S, Okamoto R, Totsuka T, Yagita H, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington.D.C
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] IL-7 is essential for the development and the persistence of chronic colitis2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Makita S, Watanabe M
- Organizer
  ICMI2007
- Place of Presentation
  東京
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] IL-7 is essential for the development and persistence of chronic colitis2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Makita S, Totsuka T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington, D.C.
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] IL-7 is essential for the development and persistence of chronic colitis2007
- Author(s)
  Totsuka T, Kanai T, Nemoto Y, Tomita T, Makita S, Totsuka T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington.D.C
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] Activated notch signaling suppresses generation of goblet cells in the human intestinal mucosa2007
- Author(s)
  Okamoto R, Tsuchiya K, Kanai T, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington, D.C.
- Year and Date
  2007-05-20
- Data Source
  KAKENHI-PROJECT-19590716
[Presentation] Ameliorating effect of anti-NKG2D in CD4+ cell-mediated murine model of chronic colitis2007
- Author(s)
  Ito Y, Kanai T, Fujii Y, Nemoto Y, Makita S, Totsuka T, Tsuchiya K, Yagita H, Watanabe M
- Organizer
  DDW 2007
- Place of Presentation
  Washington.D.C
- Year and Date
  2007-05-21
- Data Source
  KAKENHI-PROJECT-19590718
[Presentation] "シンポジウム3　難治性クローン病：病態から考えた治療アプローチ
- Author(s)
  南木康作　久松理一，金井隆典
- Organizer
  JDDW 2014
- Place of Presentation
  JDDW 2014（兵庫県神戸市）
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-24390190
[Presentation] クローン病狭窄病変に対する内視鏡的バルーン拡張術の短期・長期成績
- Author(s)
  小林拓、長沼誠、久松理一、松岡克善、中野雅、緒方晴彦、日比紀文、金井隆典
- Organizer
  第87回　日本消化器内視鏡学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Inflammatory macrophages response to stimulation by Curdlan (beta-1,3-glucan) and may contributes to the pathogenesis of inflammatory bowel disease.
- Author(s)
  Mori M, Hisamatsu T, Suzuki H, Tokutake M, Shimamura K, Mizuno S, Nakamoto N, Ebinuma H, Matsuoka K, Kanai T.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会場（京都市左京区）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24390190
[Presentation] "ワークショップ9　希少消化管疾患の臨床像と問題点
- Author(s)
  久松理一，細江直樹，金井隆典
- Organizer
  JDDW 2014
- Place of Presentation
  JDDW 2014（兵庫県神戸市）
- Year and Date
  2014-10-23 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-24390190

1. WATANABE Manabu (10175127)

# of Collaborated Projects: 14 results

# of Collaborated Products: 130 results
2. HIBI Toshifumi (50129623)

# of Collaborated Projects: 5 results

# of Collaborated Products: 37 results
3. AZUMA Miyuki (90255654)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. 寺谷俊昭 (40624408)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
5. YAGITA Hideo (30182306)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. ISHIKAWA Hiromichi (20051667)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. ARAKI Akihiro (80361690)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. HISAMATSU Tadakazu (60255437)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
9. Naganuma Makoto (00265810)

# of Collaborated Projects: 3 results

# of Collaborated Products: 40 results
10. TOTSUKA Teruji (70447465)

# of Collaborated Projects: 2 results

# of Collaborated Products: 53 results
11. OGATA Haruhiko (30177117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 24 results
12. NAKAMOTO Nobuhiro (40383749)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
13. IWAO Yasushi (40168547)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
14. TOSHIRO Sato (70365245)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
15. 三上洋平 (80528662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
16. NAGAISHI Takashi (60447464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAGAHORI Masakazu (60420254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. FUKAO Taro (20401127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. OKAZAWA Akira (50286457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KIYONO Hiroshi (10271032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAKAMURA Tetsuya (70265809)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. TSUBATA Takeshi (80197756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. OOOKA Shinya (90361691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 真壁利明 (60095651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 稲澤譲治 (30193551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 杉浦悠毅 (30590202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
27. 杉本真也 (20626387)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
28. Mizuno Shinta

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
29. NAKASE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. TAMURA Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. SUGIYAMA Kazuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. IWASAKI Yusaku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. MATANO Mami

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. SHIMIZU Mikiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. HASHIGUCHI Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. SUZUKI Hiromu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 竹中健人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 木内謙一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 筋野智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
40. 柴田理恵

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 細江直樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
42. 永石宇治

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
43. 斎藤英胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
44. 高林馨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
45. 矢田俊彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
46. 坪田昭人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
47. 白石安永

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanai Takanori 金井 隆典

KANAI Takanori 金井 隆典

金井 隆典 カナイ タカノリ

Research Projects

Research Products

Co-Researchers

Elucidation of the gut-liver-brain axis in response to host-invading bacteria and the development of treatments for gastrointestinal immune diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis of gastrointestinal immune intractable diseases via the intestinal immune response to host invading bacteria.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of the World of AhR in the intestinal environment ,followed by the diverse clinical applications.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new vaccine therapy to promote the symbiotic bacteria in gut.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To identify the mechanism of inflammatory bowel disease by using human microbe mono-associated mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Symbiosis pattern decision factors and its reeducation programPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Challenge to the cell therapy by reprogramming colitogenic memory T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Kanai Takanori 金井隆典

KANAI Takanori 金井隆典

金井隆典カナイタカノリ