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MORISHITA Ryuichi  森下 竜一

ORCIDConnect your ORCID iD *help
… Alternative Names

森下 龍一  モリシタ リュウイチ

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Researcher Number 40291439
Other IDs
External Links
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 寄附講座教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 大阪大学, 大学院医学系研究科, 寄附講座教授
2016 – 2021: 大阪大学, 医学系研究科, 寄附講座教授
2013 – 2015: 大阪大学, 医学(系)研究科(研究院), 寄附講座教授
2014: 大阪大学, 医学(系)研究科(研究院), 教授
2014: 大阪大学, 大学院医学系研究科, 寄附講座教授 … More
2012: 大阪大学, 医学(系)研究科(研究院), その他
2012: 大阪大学, 医学系研究科, 教授
2011 – 2012: 大阪大学, 医学(系)研究科(研究院), 教授
2011: 大阪大学, 医学系・研究科, 寄附講座教授
2009 – 2011: Osaka University, 医学系研究科, 寄附講座教授
2010: 大阪大学, 医学系研究科, 寄付講座教授
2005: 大阪大学, 医学系研究科, 寄附講座助手
2005: Osaka Medical College, Faculty of Medicine, Professor, 医学部, 寄付講座教授
2004 – 2005: Osaka University, Graduate School of Medicine, professor, 医学系研究科, 寄附講座教授
2004: 大阪大学, 大学院・医学研究科, 教授
2003 – 2004: Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 寄附講座教員(客員教授)
2003 – 2004: 大阪大学, 医学部, 教授
2003: 大阪大学, 医学系研究科, 寄付講座教員(客員教授)
2002: Osaka University, Graduate School of Medicine, Professor, 医学系研究科, 教授
1999 – 2002: Division of Gene Therapy Science, Osaka University, 医学系研究科, 助教授
2001: 大阪大学, 大学院・医学研究科, 助教授
2000 – 2001: 大阪大学, 医学部, 助教授
1999: 大阪大学, 大学院・医学系研究科・遺伝子治療学, 助教授
1998: Osaka University Faculty of Medicine, Associate Professor, 医学部, 助教授
1997: Osaka University Medical School, Assistant Professor, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine / Biological Sciences / General internal medicine (including Psychosomatic medicine) / Basic Section 52010:General internal medicine-related / Metabolomics / Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine / Cardiovascular medicine / Basic Section 52010:General internal medicine-related / Cardiovascular surgery … More / Otorhinolaryngology / Circulatory organs internal medicine / Urology / Biomedical engineering/Biological material science / Thoracic surgery / Kidney internal medicine / Neurology / General surgery / General internal medicine (including Psychosomatic medicine) / Human genetics / Cerebral neurosurgery / Radiation science Less
Keywords
Principal Investigator
HGF / 遺伝子治療 / 糖尿病 / 血管新生 / アポトーシス / 閉塞性動脈硬化症 / アルツハイマー病 / 血管 / NFkB / デコイ … More / VEGF / ASO / angiogenesis / gene therapy / ビュルガー病 / 心筋梗塞 / ワクチン / ベータ・アミロイド / インターロイキン-6 / 炎症 / 周辺症状 / 血液脳関門 / βアミロイド / 血管内皮細胞 / HVJ / 内皮 / E2F / 動脈硬化 / p53 / 免疫療法 / タウ / 認知症 / Apoptosis / Angiogenesis / Peripheral arterial disease / Gene Therapy / Celebralinfection / Endothelial cell / Ischemic heart disease / 遺伝子治療学 / プロスタグランディン / 内皮機能 / アフリカツメガエル / 血球形成 / NOGA / 細胞死 / 脳梗塞 / 虚血性心疾患 / endotlelial cells / CAP / 核酸医薬 / 再狭 / 再狭窄 / NFKB / emdothetial calls / hynes tersion / 血管新迷 / 再狭管 / 虚血 / 高血圧 / 閉塞性幼脈硬化症 / 脂質異常症 / 認知機能 / 脳血管 / サイトカイン / インスリン・シグナリング / 神経細胞保護効果 / 肝細胞増殖因子 / パーキンソン病 / 血管新生因子 / 細胞外基質 / 細胞移植 / 虚血性心血管病 / 血管内皮 / 胚性幹細胞 / がん / リポソーム / DNAチッブ / マイクロアレイ / マクロアレイ / 転写因子 / アンチセンス / 細胞周期 / 心筋 / がん抑制遺伝子 / Rb … More
Except Principal Investigator
遺伝子治療 / NFkB / デコイ / 転写因子 / gene therapy / decoy / 動脈硬化 / E2F / 大動脈瘤 / HVJ-liposome / NFκB / HVJ-リポソーム法 / Gene therapy / アンチセンス / 再狭窄 / HGF / 遺伝子導入 / 老化 / 癌 / 腹部大動脈瘤 / ets / Hepatocyte Growth Factor / Optison / 分子治療 / Immunoliposome / HVJ-liposome method / 血管新生 / atherosclerosis / restenosis / ベクター / 閉塞性動脈硬化症 / angiotensinogen / gene analysis / gene / hypertension / 中枢神経系 / 遺伝子導入法 / アポトーシス / 核酸医薬 / 平滑筋 / 血管 / 転移 / 免疫 老化 / 糖鎖 / 免疫 / 複合糖質ワクチン / stentgraft / decoy型核酸医薬 / stent graft / 分子治療製剤 / 血管内治療 / ステントグラフト / transgenic mice / oral HPV infection / human papillomavirus / ウイルス / CRISPR/Cas9 / liquid biopsy / 咽頭感染率 / トランスジェニックマウス / リキッドバイオプシー / 咽頭感染 / 中咽頭癌 / ヒトパピローマウイルス / 免疫学 / 循環器・高血圧 / 肺高血圧ラットモデル / ET-1ペプチドワクチン / エンドセリン-1 / IL-17A / エンドセリン-1 / ワクチン / 肺動脈性肺高血圧症 / RANKL / Osteoprotegerin / 血管石灰化 / 炎症 / 石灰化 / Atherosclerosis / Restenosis / Graft failure / Aneurysm / Decoy oligonucleotides / Molecular therapy / J-PRAN / MMP / キメラデコイ / グラフト不全 / 動脈瘤 / kidney transplantation / 腎移植 / おとり型核酸医薬(デコイ) / molecular therapy / polymer / drug delivery / decoy oligodeoxynucleotides / 徐放化製剤 / 慢性関節リウマチ / デコイオリゴヌクレオチド / ポリマー / ドラッグデリバリー / デコイ核酸 / Angiogenesis / Apoptosis / Myocardial fibrosis / Dilated cardiomyopathy (DCM) / in vivo genetrausfection / Hepatocyte growth factor (HGF) / 虚血再灌流障害 / 線維化 / 拡張型心筋症 / in vivo gene transfection / 肝細胞増殖因子(HGF) / Gene targeting / Glomerulonephritis / NF_kB / Transcription factor decoy / immunoliposome / ターゲェティング / 糸球体腎炎 / transcriptional cis-element / gene transfer / angiotensin converting enzyme / central nervous system / renin-angiotensin system / 神経細胞 / 血圧調節機構 / アンジオテンシンII / 転写調節因子 / おとり型核酸 / アンジオテンシノージェン / アンジオテンシン変換酵素 / レニン-アンジオテンシン系 / decoy oligonucleotides / vector / 心筋梗塞 / HVJ-liposome法 / cardiovascular remodeling / aging / phenotypic modulation / gene expression / smooth muscle / blood vessels / アテレクトミ- / 組織因子 / Znフィンガー / INOS / プロモーター / BTEB2 / 血管平滑筋 / Klotho / Smooth muscle / カルポニン / HB-EGF / クロマチン転写 / klotho / 心血管リモデリング / 形質変換 / 遺伝子発現調節 / peripheral arterial disease / vascular remodeling / アンジオテンシノジェン / レニン・アンジオテンシン系 / 遺伝子解析 / 遺伝子 / 高血圧 / hepertension / 悪性黒色腫 / 癌幹細胞 / 乳癌 / ペリオスチン / 肺転移 / Wnt シグナル / 中和抗体 / 癌転移 / トリプルネガティブ乳癌 / 脂質異常 / 肥満 / インスリン抵抗性 / 安全性 / 血液・脳関門 / 超音波増強剤 / アストロサイト・グリア系 / 副作用 / 肝細胞増殖因 / アルツハイマー病 / 中枢性変性疾患 / 超音波 / Neural stem cells / Hepatocyte geowth factor / Embryonic stem cell / Neuronal progenitor / Neuronal differentiation / Neural stem cell / Hepatocyte growth factor / NF-kappaB / 放射線治療 / HVJ / 放射線 / NF-κB / 遺伝子発現転写調節 / 内皮 / 悪えき質 / がん Less
  • Research Projects

    (36 results)
  • Research Products

    (209 results)
  • Co-Researchers

    (66 People)
  •  認知症関連病的蛋白の翻訳後修飾を標的としたワクチン療法の開発Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Investigation of vaccines using glycolipid antigens for anti-aging

    • Principal Investigator
      Iwabu Yuka
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Osaka University
  •  Development of vaccine therapy for pulmonary arterial hypertension

    • Principal Investigator
      Ogihara Yoshito
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Mie University
  •  Comprehensive study for control of human papillomavirus-related oropharyngeal squamous cell carcinoma

    • Principal Investigator
      Inohara Hidenori
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Osaka University
  •  Endovascular treatment with oligonucleotide therapeutics for aortic aneurysm

    • Principal Investigator
      SHIRAYA Suguru
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Tottori University
  •  Elucidation of OPG-RANKL-TRAIL system in the process of abdominal aortic aneurysm progression

    • Principal Investigator
      Miyake Takshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular medicine
    • Research Institution
      Osaka University
  •  DNA vaccine for diabetes and dyslipidemiaPrincipal Investigator

    • Principal Investigator
      MORISHITA Ryuichi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      Osaka University
  •  New target of the extra cellular matrix protein aganist cancer

    • Principal Investigator
      TANIYAMA Yoshiaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Osaka University
  •  Development of a novel therapy for Alzheimer's disease based on vascular modificationPrincipal Investigator

    • Principal Investigator
      MORISHITA Ryuichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Analysis of regulatory molecule on vascular aging

    • Principal Investigator
      KATSUYA Tomohiro
    • Project Period (FY)
      2009 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Analysis of molecular link between Alzheimer' s disease and diabetes mellitusPrincipal Investigator

    • Principal Investigator
      MORISHITA Ryuichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Osaka University
  •  肝細胞増殖因子(HGF)遺伝子を用いたパーキンソン病に対する遺伝子治療の検討Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  脳への超音波遺伝子導入法の開発と脳変性疾患治療への応用

    • Principal Investigator
      SATO Naoyuki
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Osaka University
  •  胚性幹細砲を用いた、心血管発生機構の解明、ならびに難治性心血管病における組織再生Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  肝細胞増殖因子(HGF)による神経幹細胞の増殖・分化誘導の制御

    • Principal Investigator
      岩間 亨, 郭 泰彦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Gifu University
  •  The effect of simultaneous transfection of HGF gene-plasmid and NFκB-decoy using ultrasound exposure with contrast agent in a rat kidney allograft model

    • Principal Investigator
      AZUMA Haruhito
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Osaka Medical College
  •  The development of molecular therapy using decoy oligonucleotides : for clinical applications.

    • Principal Investigator
      AOKI Motokuni
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  脳への新規遺伝子導入法開発と脳神経疾患治療への応用Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  おとり型核酸医薬と非ウイルスベクターの遺伝子導入法開発による新規がん治療戦略Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  核酸医薬(NF-κB decoy)を用いた遺伝子放射線治療

    • Principal Investigator
      田中 英一
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      Osaka University
  •  Clinical Application of Hepatocyte Growth Factor (HGF) to cardiovascular disease: Its molecular mechanisms and possibility of molecular therapy.Principal Investigator

    • Principal Investigator
      MORISHITA Yuichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Development of slow release reagent of NFkB decoy oligodeoxynucleotides for the treatment of rheumatic arthritis

    • Principal Investigator
      KANEDA Yasufumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      OSAKA UNIVERSITY
  •  マイクロアレイを利用した血管内皮細胞の分化・再生因子同定と診断・治療への応用Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  血管の発生分化と病態形成

    • Principal Investigator
      NAGAI Ryozo
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      The University of Tokyo
  •  Application of In vivo Gene Transfer for the Analysis of Pathophysiology and Treatment in the Cardiovascular DiseasePrincipal Investigator

    • Principal Investigator
      MORISHITA Ryuichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Researches on novel techniques of organ-selective gene therapy in thoracic surgery

    • Principal Investigator
      MATSUDA Hikaru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Thoracic surgery
    • Research Institution
      Osaka University
  •  転写因子NFkBをターゲットとしたおとり型核酸医療薬を用いたがん遺伝子治療の開発

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  おとり型核酸化合物(デコイ)を用いた転写因子の生物作用の個体での解析Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  Development of strategies of gene therapy for renal diseases

    • Principal Investigator
      HIGAKI Jitsuo
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  心筋細胞における癌抑制遺伝子の機能解明に関する研究-細胞周期と分化のネットワーク機構の解析-Principal Investigator

    • Principal Investigator
      森下 竜一
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Gene Therapy in the Cardiovascular Disease

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Molecular mechanisms of phenotypic modulation and growth of smooth muscle cells

    • Principal Investigator
      NAGAI Ryozo
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      University of Tokyo
      Gunma University
  •  Gene therapy for cardiovascular diseases : Development of newvector and evaluation of clinical strategy

    • Principal Investigator
      TOSHIO Ogihara
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      OSAKA University
  •  Role of Hepatocyte Growth Factor in the Pathogeresis of Cardioucscalon DiseasePrincipal Investigator

    • Principal Investigator
      MOCISHITE Rynichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University
  •  Role of brain renin-angiotensin system in the regulation of blood presure

    • Principal Investigator
      MORIGUCHI Atsushi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Osaka University
  •  Gene analysis of hypertension and development of new therapy

    • Principal Investigator
      OGIHARA Toshio
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Osaka University

All 2023 2022 2021 2018 2014 2013 2012 2011 2010 2009 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Cuff Opin Pharmacol Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides.2004

    • Author(s)
      Morishita R
    • Publisher
      Curr Opin Pharmacol
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Book] Gene Therapy vs Pharmacotherapy.2004

    • Author(s)
      Morishita R
    • Publisher
      Cardiovascular Genomics
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Book] Therapeutic potential of oligonucleotide-based therapy in cardiovascular disease.2003

    • Author(s)
      Morishita R
    • Publisher
      Biodrugs
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Book] Dyslipidemia - From Prevention to Treatment, Chapter 7, Functions of OSBP/ORP Family Proteins and Their Relation to Dyslipidemia

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] High-fat diet-induced diabetic conditions exacerbate cognitive impairment in a mouse model of Alzheimer’s disease via a specific tau phosphorylation pattern2023

    • Author(s)
      Yuki Ito,Shuko Takeda,Tsuneo Nakajima,Akane Oyama,Hikari Takeshita,Kunihiro Miki,Yoichi Takami,Yasushi Takeya,Munehisa Shimamura,Hiromi Rakugi,Ryuichi Morishita
    • Journal Title

      The Journal of Prevention of Alzheimer's Disease

      Volume: - Issue: 1 Pages: 138-148

    • DOI

      10.14283/jpad.2023.85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K21405, KAKENHI-PROJECT-23K24229
  • [Journal Article] Antiepileptic drugs modulate Alzheimer-related tau aggregation in a neuronal activity-independent manner.2023

    • Author(s)
      Yuki Ito, Shuko Takeda, Sayaka Moroi, Tsuneo Nakajima, Akane Oyama, Kunihiro Miki, Nanami Sugihara, Yoichi Takami, Yasushi Takeya, Munehisa Shimamura, Hiromi Rakugi, Ryuichi Morishita.
    • Journal Title

      Dementia and Geriatric Cognitive Disorders.

      Volume: - Issue: 2 Pages: 108-116

    • DOI

      10.1159/000529915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15701, KAKENHI-PROJECT-23K21405, KAKENHI-PROJECT-23K24229
  • [Journal Article] A novel chronic dural port platform for continuous collection of cerebrospinal fluid and intrathecal drug delivery in free-moving mice.2022

    • Author(s)
      Tsuneo Nakajima,Shuko Takeda,Yuki Ito,Akane Oyama,Yoichi Takami,Yasushi Takeya,Koichi Yamamoto,Ken Sugimoto,Hideo Shimizu,Munehisa Shimamura,Hiromi Rakugi, Ryuichi Morishita.
    • Journal Title

      Fluids and Barriers of the CNS.

      Volume: 19 Issue: 1 Pages: 1-15

    • DOI

      10.1186/s12987-022-00331-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K15701, KAKENHI-PROJECT-23K21405, KAKENHI-PROJECT-23K24229
  • [Journal Article] Periostin Short Fragment with Exon 17 via Aberrant Alternative Splicing Is Required for Breast Cancer Growth and Metastasis2021

    • Author(s)
      Yuka Ikeda-Iwabu, Yoshiaki Taniyama, Naruto Katsuragi, Fumihiro Sanada, Nobutaka Koibuchi, Kana Shibata, Kenzo Shimazu, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Cells

      Volume: 10 Issue: 4 Pages: 892-892

    • DOI

      10.3390/cells10040892

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07466, KAKENHI-PROJECT-20K07659, KAKENHI-PROJECT-18H02806
  • [Journal Article] Therapeutic vaccine against DPP4 improves glucose metabolism in mice.2014

    • Author(s)
      Pang Z, Nakagami H, Osako MK, Koriyama H, Nakagami F, Tomioka H, Shimamura M, Kurinami H, Takami Y, Morishita R, Rakugi H.
    • Journal Title

      Proc Natl Acad Sci U S A. 2014 ;111(13):E1256-63.

      Volume: 111(13)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25670433
  • [Journal Article] Development of novel DNA vaccine for VEGF in murine cancer model.2013

    • Author(s)
      Kyutoku M
    • Journal Title

      Sci Rep.

      Volume: 3 Issue: 1 Pages: 3380-3380

    • DOI

      10.1038/srep03380

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112005, KAKENHI-PROJECT-24300330, KAKENHI-PROJECT-25670433
  • [Journal Article] Increased Blood-Brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model.2013

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
    • Journal Title

      Neurobiology of Aging

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012

    • Author(s)
      Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
    • Journal Title

      FASEB J

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Dual effects of statins on Abeta metabolism : Up-regulation of degradation of APP-CTF and Abeta clearance2012

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Neurodegenerative diseases

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Neuroscience

      Volume: 186 Pages: 110-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012

    • Author(s)
      Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, Morishita R
    • Journal Title

      Stroke

      Volume: 43 Pages: 1108-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients : Potential Diagnostic Method for Alzheimer Disease2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Dementia and Geriatric Cognitive Disorders

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Oral Glucose Loading Modulates PlasmaAβLevel in Alzheimer DiseasePatients Potential Diagnostic Method for Alzheimer Disease2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
    • Journal Title

      Dementia and GeriatricCognitive Disorders

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients : Potential Diagnostic Method for Alzheimer Disease2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Dementia and Geriatric Cognitive Disorders

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] HIG1, a novelregul ator of mitochondrialγ-secretase, ma intains normal mitochondrial function2012

    • Author(s)
      Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
    • Journal Title

      FASEB J

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Dual effects of statins on Abeta metabolism : Up-regulation of degradation of APP-CTF and Abeta clearance2012

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Neurodegenerative diseases

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] HIG1, a novel regulator of mitochondrial γ-secretase, maintains normal mitochondrial function2012

    • Author(s)
      Hayashi H, Nakagami H, Takeichi M, Shimamura M, Koibuchi N, Oiki E, Sato N, Koriyama H, Mori M, Gerardo Araujo R, Maeda A, Morishita R, Tamai K, Kaneda Y
    • Journal Title

      FASEB J

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012

    • Author(s)
      Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, and Morishita R
    • Journal Title

      Stroke

      Volume: 43 Pages: 1108-1114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Oral Glucose Loading Modulates Plasma Aβ Level in Alzheimer Disease Patients: Potential Diagnostic Method for Alzheimer Disease.2012

    • Author(s)
      ShukoTakeda, Naoyuki Sato*, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
    • Journal Title

      Dementia and Geriatric Cognitive Disorders

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
    • Journal Title

      Neuroscience

      Volume: 186 Pages: 110-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse2012

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Neuroscience

      Volume: 186 Pages: 110-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Role of Central Nervous System Periostin in Cerebral Ischemia2012

    • Author(s)
      Shimamura M, Taniyama Y, Katsuragi N, Koibuchi N, Kyutoku M, Sato N, Allahtavakoli M, Wakayama K, Nakagami H, Morishita R
    • Journal Title

      Stroke

      Volume: 43 Pages: 1108-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R
    • Journal Title

      Mol Biosyst

      Volume: 7(6) Pages: 1822-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011

    • Author(s)
      Shimamura M, Sato N, Morishita R
    • Journal Title

      Curr Gene Ther

      Volume: 11(6) Pages: 491-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R
    • Journal Title

      Mol Biosyst.

      Volume: 7(6) Pages: 1822-1827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011

    • Author(s)
      Shimamura M, Sato N, Morishita R
    • Journal Title

      Curr Gene Ther.

      Volume: 11(6) Pages: 491-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Molecular mechanisms linking diabetes mellitus and Alzheimer disease : beta-amyloid peptide, insulin signaling, and neuronal function2011

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R
    • Journal Title

      Mol Biosyst

      Volume: 7(6) Pages: 1822-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Experimental and clinical application of plasmid DNA in the field of central nervous diseases2011

    • Author(s)
      Shimamura M, Sato N, Morishita R
    • Journal Title

      Curr Gene Ther

      Volume: 11(6) Pages: 491-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus: a missing link to therapeutic potential.2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Tomomi Fujisawa, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Current Aging Science

      Volume: 4 Pages: 118-127

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Novel microdialysis method to assess neuropeptides and large molecules in free-moving mouse.2011

    • Author(s)
      Shuko Takeda, Naoyuki Sato*, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi and Ryuichi Morishita
    • Journal Title

      Neuroscience

      Volume: 186 Pages: 110-9

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Diabetes accelerated memory dysfunction via cerebrovascular inflammation and A. deposition in an Alzheimer mouse model with diabetes.2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, and Ryuichi Morishita
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 13, 107 Pages: 7036-41

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
    • Journal Title

      Proceeding of National Academy of Sciences of United States of America

      Volume: 107 Pages: 7036-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance2010

    • Author(s)
      Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 285 Pages: 22091-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2010

    • Author(s)
      Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
    • Journal Title

      Current Aging Science

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease2010

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Journal Title

      Molecular BioSystems

      Volume: 6 Pages: 1760-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Reduction of Brain β-amyloid (Aβ) by fluvastatin, a hydroxymethylglutaryl-CoA reductase inhibitor, thrpugh increase in degradation of amyloid precursor protein C-terminal fragnents (APP-CTFs) and Aβ clearance2010

    • Author(s)
      Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R.
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 285 Pages: 22091-102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse model with diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
    • Journal Title

      Proceedings of National Academy of Sciences of United States of America. (In press.)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Diabetes-accelerated memory dysfunction via cerebrovascular inflammation and Aβ deposition in an Alzheimer mouse with diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
    • Journal Title

      Proceeding of National Academy of Sciences of United States of America

      Volume: 107 Pages: 7036-7041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Identification of Evidence Suggestive of an Association with Peripheral Arterial Disease at the OSBPL10 Locus by Genome-Wide Investigation in the Japanese Population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Sugimoto K, Yamashita H, Takami Y, Maeda S, Kubo M, Takahashi A, Nakamura Y, Ogihara T, Rakugi H, Kaneda Y, Morishita R.
    • Journal Title

      J Atheroscler Thromb

      Volume: 17(10) Pages: 1054-62

    • NAID

      130004845291

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      Hypertension Res.

      Volume: 33 Pages: 511-514

    • NAID

      10026396580

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Reduction of brain A. by fluvastatin, an HMG-CoA reductase inhibitor, through increase in degradation of APP-CTFs and A. clearance.2010

    • Author(s)
      Mitsuru Shinohara, Naoyuki Sato, Hitomi Kurinami, Daisuke Takeuchi, Shuko Takeda, Munehisa Shimamura, Toshihide Yamashita, Yasuo Uchiyama, Hiromi Rakugi, and Ryuichi Morishita
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 285 Pages: 22091-22102

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Plasma Beta-Amyloid as Potential Biomarker of Alzheimer Disease: Possibility of Diagnostic Tool of Alzheimer Disease.2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
    • Journal Title

      Molecular BioSystems

      Volume: 6 Pages: 1760-1766

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Plasma β-amyloid as potential biomarker of Alzheimer disease : possibility of diagnostic tool for Alzheimer disease2010

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Journal Title

      Molecular BioSystems

      Volume: 6 Pages: 1760-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Animal Models of Alzheimer Disease for Translational Research: Current and Future Concepts. Horizons in Neuroscience Research. Volume 4 (Hardcover)2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      Nova Science Publishers

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Variation in OSBPL10 is associated with dyslipidemia.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Akasaka H, Saitoh S, Shimamoto K, Ogihara T, Kaneda Y, Morishita R, Rakugi H.
    • Journal Title

      Hypertens Res

      Volume: 33(5) Pages: 511-4

    • NAID

      10026396580

    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.2010

    • Author(s)
      Koriyama H, Nakagami H, Katsuya T, Morishita R, Rakugi H, 他5名
    • Journal Title

      J Atheroscler Thromb.

      Volume: 17 Pages: 1054-1062

    • NAID

      130004845291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Journal Article] Role of insulin signaling in the interaction between Alzheimer disease and diabetes mellitus : a missing link to therapeutic potential.2010

    • Author(s)
      Sato N, Takeda S, Uchio-Yamada K, Ueda H, Fujisawa T, Rakugi H, Morishita R.
    • Journal Title

      Current Aging Science

      Volume: (In Press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cogniti impairment associated with recovery of neurovascular coupling.2009

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Morishita R.
    • Journal Title

      Biochem Biophys Res Commun. 385

      Pages: 193-197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Angiotensin Receptor Blocker Prevented b-Amyloid-Induced Cognitive Impairment Associated With Recovery of Neurovascular Coupling2009

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru S hinohara, Kazue, Niisato, Masanobu Kano, Toshio Ogihara, Hiromi Rakugi and Ryuichi Morishita
    • Journal Title

      Hypertension

      Volume: 54 Pages: 1345-1352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Angiotensin receptor blocker prevented beta-amyloid-induced cogniti impairment associated with recovery of neurovascular coupling.2009

    • Author(s)
      Takeda S, Sato N, Takeuchi D, Kurinami H, Shinohara M, Niisato Kano M, Ogihara T, Rakugi H, Morishita R.
    • Journal Title

      Hypertension. 54

      Pages: 1345-1352

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Validation of Abetal-40 administration into mouse cerebroventricles as an animal model for Alzheimer disease.2009

    • Author(s)
      Takeda S, Sato N, Niisato K, Takeuchi D, Kurinami H, Shinohara M, Rakugi H, Kano M, Morishita R.
    • Journal Title

      Brain Res. 1280

      Pages: 137-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] Alzheimer disease-associated peptide, amyloid beta4O, inhibits vascular regeneration with induction of endothelial autophagy.2009

    • Author(s)
      Hayashi S, Sato N, Yamamoto A, lkegame Y, Nakashima S, Ogihara T, Morishita R.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 29

      Pages: 1909-1915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Journal Article] An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney.2005

    • Author(s)
      Koike H, Tomita N, Azuma H, Taniyama Y, Yamasaki K, Kunugiza K, Ogihara T, Morishita R
    • Journal Title

      J Gene Med. 7・1

      Pages: 108-116

    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Recent Progress in Cerebrovascular Gene Therapy2005

    • Author(s)
      Sato N, Shimamura M, Morishita R.
    • Journal Title

      Current Neurovascular Research. 2・3

      Pages: 235-247

    • Data Source
      KAKENHI-PROJECT-16659089
  • [Journal Article] An efficient gene transfer method mediated by ultrasound and microbubbles into the kidney2005

    • Author(s)
      Koike H, Tomita N, Azuma H, Taniyama Y, Yamasaki K, Kunugiza Y, Tachibana K, Ogihara T, Morishita R
    • Journal Title

      J Gene Med 7-1

      Pages: 108-116

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease by therapeutic angiogenesis.2004

    • Author(s)
      Morishita R.
    • Journal Title

      Hypertension 44

      Pages: 203-209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Journal Article] Application of decoy oligodeoxynucleotides-based approach to renal diseases.2004

    • Author(s)
      Tomita N, Azuma H, Kanada Y, Ogihara T, Morishita R
    • Journal Title

      Curr Drug Targets 5・8

      Pages: 717-733

    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Application of decoy oligodeoxynucleotides-based approach to renal diseases.2004

    • Author(s)
      Tomita N, Azuma H, Kaneda Y, Ogihara T, Morishita R.
    • Journal Title

      Curr Drug Targets 5(8)

      Pages: 717-33

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease by therapeutic angiogenesis.2004

    • Author(s)
      Morishita R
    • Journal Title

      Hypertension 44

      Pages: 203-209

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Journal Article] Gene Therapy vs Pharmacotherapy.2004

    • Author(s)
      Morishita R.
    • Journal Title

      Cardiovascular Genomics

      Pages: 137-156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Journal Article] Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides.2004

    • Author(s)
      Morishita R.
    • Journal Title

      Curr Opin Pharmacol 4(2)

      Pages: 139-146

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Journal Article] Application of decoy oligodeoxynucleotides-based approach to renal diseases2004

    • Author(s)
      Tomita N, Azuma H, Kaneda Z, Ogihara T, Morishita R
    • Journal Title

      Curr Drug Targets 5-8

      Pages: 717-733

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Therapeutic potential of oligonucleotide-Based therapy in cardiovascular disease.2003

    • Author(s)
      Morishita R.
    • Journal Title

      Biodrugs 17(6)

      Pages: 383-389

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590744
  • [Journal Article] Transfection of NFkappaB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts.2003

    • Author(s)
      Azuma H, Tomita N, Kaneda Y, Koike H, Ogihara T, Katsuoka Y, Morishita R.
    • Journal Title

      Gene Ther. 10・5

      Pages: 415-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Transfection of NFkappaB-decoy oligodeoxynucleotides using efficient ultrasound-mediated gene transfer into donor kidneys prolonged survival of rat renal allografts.2003

    • Author(s)
      Azuma H, Tomita N, Kaneda Y Koike H, Ogihara T, Katsuoka Y, Morishita R.
    • Journal Title

      Gene Ther. 10-5

      Pages: 415-425

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases.2003

    • Author(s)
      Tomita N, Azuma H, Kaneda Y, Ogihara T, Morishita R.
    • Journal Title

      Curr Drug Targets 4-4

      Pages: 339-346

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Gene therapy with transcription factor decoy oligonucleotides as a potential treatment for cardiovascular diseases.2003

    • Author(s)
      Tomita N, Azuma H, Kaneda Y, Ogihara T, Morishita R.
    • Journal Title

      Curr Drug Targets 4・4

      Pages: 339-46

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390499
  • [Journal Article] Development of new screening system for Alzheimer Disease, in vitro Aβ sink assay, to identity the dissociation of soluble Aβ from fibrils.

    • Author(s)
      Sato N, Okochi M, Taniyama Y, Kurinami H, Shimamura M, Takeuchi D, Hamada H, Fukumori A, Kiyosue K, Taguchi T, Tanaka T, Miyasaka M, Takeda M, Ogihara t, Morishita R.
    • Journal Title

      Neuobiology of Disease (in press)

    • Data Source
      KAKENHI-PROJECT-16659089
  • [Journal Article] Gene transfer into adult rat spinal cord using naked plasmid DNA and ultrasound microbubbles.

    • Author(s)
      Shimamura, M., Sato, N., Taniyama, Y., Kurinami, H., Tanaka, H., Takami, T., Ogihara, T., Tohyama, M., Kaneda, Y., Morishita, R.
    • Journal Title

      J.Gene Med (in press)

    • Data Source
      KAKENHI-PROJECT-16659089
  • [Journal Article] Differential Regulation of Amyloid Precursor Protein /Presenilin 1 Interaction during Aβ40/42 Production Detected Using Fusion Constructs.

    • Author(s)
      Naoyuki Sato, Masayasu Okochi, Mitsuru Shinohara, Gopal Thinakaran, Shuko Takeda, Akio Fukumori, Motoko Shinohara-Noma, Mari Mori-Ueda, Hizuki Hamada, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Journal Title

      PLoS ONE

      Volume: 7(11)

    • Data Source
      KAKENHI-PROJECT-22390145
  • [Patent] 透析プローブ2010

    • Inventor(s)
      武田朱公、里直行、森下竜一、西野博仁、生村和子
    • Industrial Property Rights Holder
      大阪大学、株式会社エイコム
    • Acquisition Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Patent] 透析プローブ2010

    • Inventor(s)
      武田朱公、里直行、森下竜一、西野博仁、生村和子
    • Industrial Property Rights Holder
      大阪大学、株式会社エイコム
    • Acquisition Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Patent] 新規マイクロダイアライシス回路を用いた脳内物質の精密測定法2010

    • Inventor(s)
      西野博仁、生村和子、武田 朱公,里 直行,森下 竜一
    • Filing Date
      2010-04-26
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Patent] 透析プローブ2010

    • Inventor(s)
      武田朱公、里直行、森下竜一、西野博仁、生村和子
    • Industrial Property Rights Holder
      大阪大学、株式会社エイコム
    • Acquisition Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 光刺激による明暗リズムの変化を用いたせん妄マウスモデルの開発2022

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、大山 茜、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第33回日本老年医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] Diabetes mellitus aggravates behavioral deficit and increases site-specific phosphorylation of tau protein in Alzheimer's disease mouse model.2022

    • Author(s)
      Yuki Ito, Shuko Takeda, Tsuneo Nakajima, Akane Oyama, Hikari Takeshita, Kunihiro Miki, Yoichi Takami, Yasushi Takeya, Hiromi Rakugi, Ryuichi Morishita.
    • Organizer
      The 29th Scientific Meeting of the International Society of Hypertension
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 髄液中リン酸化Neurofilament heavy chainと脳白質病変体積との関連2022

    • Author(s)
      中嶋 恒男、武田 朱公、伊藤 祐規、鷹見 洋一、山本 浩一、竹屋 泰、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 髄液中リン酸化Neurofilament heavy chainは脳血管障害の重症度を反映する2022

    • Author(s)
      中嶋 恒男、武田 朱公、伊藤 祐規、鷹見 洋一、山本 浩一、竹屋 泰、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第64回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 抗てんかん薬はアルツハイマー病におけるタウ凝集体形成に対して影響を及ぼす2022

    • Author(s)
      伊藤 祐規、武田 朱公、諸井 彩加、中嶋 恒男、三木 国煕、杉原 七海、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第33回日本老年医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] マウス髄液を用いた神経疾患病態解明のための新規プラットフォームとしてのChronic Dural Port 法の開発2022

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、伊藤 祐規、鷹見 洋一、山本 浩一、竹屋 泰、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第12回日本脳血管・認知症学会総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] せん妄の分子病態研究に資する認知症マウスを用いたプレクリニカルモデルの開発2022

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、大山 茜、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第12回日本脳血管・認知症学会総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] アルツハイマー病のBiological subtypeと脳白質病変の特徴2022

    • Author(s)
      中嶋 恒男、武田 朱公、伊藤 祐規、鷹見 洋一、山本 浩一、竹屋 泰、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第64回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] マウス髄液を用いた病態研究プラットフォームとしてのChronic Dural Port法の開発2022

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、伊藤 祐規、鷹見 洋一、竹屋 泰、杉本 研、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      第41回日本認知症学会学術集会/第37回日本老年精神医学会 [合同開催]
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 糖尿病合併認知症においてみられるアルツハイマー病関連タウ蛋白の特異的リン酸化パターン2022

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、大山 茜、竹下 ひかり、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 抗てんかん薬がタウ凝集体形成へ及ぼす影響の多様性2022

    • Author(s)
      三木 国煕、伊藤 祐規、武田 朱公、諸井 彩加、中嶋 恒男、大山 茜、杉原 七海、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第41回日本認知症学会学術集会/第37回日本老年精神医学会 [合同開催]
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] アルツハイマー病サブタイプにおける脳白質病変容積の解析2022

    • Author(s)
      中嶋 恒男、武田 朱公、伊藤 祐規、鷹見 洋一、山本 浩一、竹屋 泰、杉本 研、樂木 宏実、森下 竜一
    • Organizer
      第22回日本抗加齢医学会総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] マウス髄液を用いたバイオマーカー研究のための新規プラットフォームとしてのChronic Dural Port法の開発2022

    • Author(s)
      中嶋 恒男、武田 朱公、大山 茜、伊藤 祐規、鷹見 洋一、竹屋 泰、杉本 研、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      第11回日本認知症予防学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] アルツハイマー病biological subtypeにおける脳白質病変の定量解析2022

    • Author(s)
      中嶋 恒男、武田 朱公、伊藤 祐規、三木 国煕、杉原 七海、鷹見 洋一、竹屋 泰、山本 浩一、樂木 宏実、森下 竜一
    • Organizer
      第41回日本認知症学会学術集会/第37回日本老年精神医学会 [合同開催]
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] A site-specific phosphorylation of tau protein induced by diabetes mellitus exacerbates behavioral defect in Alzheimer's disease mouse model.2022

    • Author(s)
      Yuki Ito、Shuko Takeda、Tsuneo Nakajima、Akane Oyama、Hikari Takeshita、Kunihiro Miki、Yoichi Takami、Yasushi Takeya、Hiromi Rakugi、Ryuichi Morishita
    • Organizer
      第26回日本心血管内分泌代謝学会学術総会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 糖尿病は脳内タウ蛋白のリン酸化パターンの変化を介してアルツハイマー病マウスの認知機能障害を増悪させる2022

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、大山 茜、竹下 ひかり、三木 国煕、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      脳心血管抗加齢研究会第18回学術大会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] 糖尿病は特異的なパターンでタウのリン酸化を増加させることでアルツハイマー病マウスの認知機能障害を増悪させる2022

    • Author(s)
      伊藤 祐規、武田 朱公、中嶋 恒男、大山 茜、竹下 ひかり、三木 国煕、鷹見 洋一、竹屋 泰、樂木 宏実、森下 竜一
    • Organizer
      第33回日本老年医学会近畿地方会
    • Data Source
      KAKENHI-PROJECT-23K24229
  • [Presentation] Periostin short fragment with exon 17 is required for breast cancer growth and metastasis.2021

    • Author(s)
      Yoshiaki Taniyama, Yuka Ikeda-Iwabu, Kana Shibata, Tatsuya Fujikawa, Yuko Kanemoto, Kenzo Shimazu, Ryuichi Morishita
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] ループス腎炎モデルにおける抗 IL17A ワクチンの有効性2018

    • Author(s)
      池田裕香、中神啓徳、森下竜一
    • Organizer
      脳心血管抗加 齢研究会2018 (第16回学術集会)
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Effect of anti-cytokine vaccine in lupus-like nephritis mode2018

    • Author(s)
      池田裕香、郡山弘、中神啓徳、森下竜一
    • Organizer
      第 47 回 日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Efficacy of anti-IL17A vaccine in lupus-like nephritis model2018

    • Author(s)
      池田裕香、中神啓徳、森下竜一
    • Organizer
      第 16 回 日韓血管生物合同シンポジウム
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07466
  • [Presentation] Role of adult common desease in the development of Alzheimer disease: Application to diagnostic and therapeutic indication2013

    • Author(s)
      Naoyuki Sato, Ryuichi Morishita
    • Organizer
      24th Biennial Joint Meeting
    • Place of Presentation
      Cancun, Mexico
    • Year and Date
      2013-04-22
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Amyloid precursor protein/presenilin 1 interaction is differentially regulated during Abeta40/42 production: detection using fusion constructs2013

    • Author(s)
      N Sato, M Okochi, M Shinohara, G Thinakaran, S Takeda, A Fukumori, M Shinohara-Noma, M Mori-Ueda, H Hamada, M Takeda, H Rakugi, R Morishita
    • Organizer
      The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
    • Place of Presentation
      Italy
    • Year and Date
      2013-03-09
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes increases tau phosphorylation in APP mice: evidence that Abeta is prerequisite, but insufficient to cause tau phosphorylation2013

    • Author(s)
      N Sato, M Mori-Ueda, T Tanaka, S Takeda, K Uchio-Yamada, H Ueda, M Shinohara, S Murayama, M Takeda, H Rakugi, R Morishita
    • Organizer
      The 11th International Conference on Alzheimer's & Parkinson's Diseases AD/PD 2013
    • Place of Presentation
      Italy
    • Year and Date
      2013-03-10
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      KEYSTONE SYMPOSIA
    • Place of Presentation
      Colorado, USA
    • Year and Date
      2012-02-28
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      KEYSTONE SYMPOSIA- ApoE, Alzheimer's and Lipoprotein Biology
    • Place of Presentation
      Keystone, Colorado
    • Year and Date
      2012-02-28
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] The mechanisms by which diabetes mellitus increases the risk of Alzheimer's disease2012

    • Author(s)
      Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Keystone Symposia, Aging and Diseases of Aging
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-10-25
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Roles of beta-amyloid and insulin resistance in the interaction between diabetes mellitus and Alzheimer's disease2012

    • Author(s)
      Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Gordon Research Conferences, Neurobiology of Brain Disorders
    • Place of Presentation
      Stonehill College
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Old APPxob/ob mice showed highly increased level of tau phosphorylation in brain2012

    • Author(s)
      Naoyuki Sato, Mari Mori-Ueda, Toshihisa Tanaka, Shuko Takeda, Kozue Uchio-Yamada, Hironori Ueda, Mitsuru Shinohara, Shigeo Murayama, Masatoshi Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Neuroscience 2012
    • Place of Presentation
      New Orleans
    • Year and Date
      2012-10-15
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] コレステロール代謝・輸送系制御機構における細胞機能・老化の解析2012

    • Author(s)
      勝谷友宏、郡山弘、中神啓徳、森下竜一
    • Organizer
      第54回日本老年医学会学術集会
    • Place of Presentation
      神戸
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-21390223
  • [Presentation] Statins up-regulate APP-CTF degradation and Abeta clearance2012

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      KEYSTONE SYMPOSIA
    • Place of Presentation
      Colorado, USA
    • Year and Date
      2012-02-28
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      AAIC (Alzheimer Association International Conference) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-10
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Grobal Alzheimer's Research Summit
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      AAIC(Alzheimer Association International Conference) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 新規マイクロダイアリシス法開発とアルツハイマー病研究への応用2011

    • Author(s)
      里直行、武田朱公、樂木宏実、森下竜一
    • Organizer
      第15回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病がアルツハイマー病の後天的危険因子である機序2011

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 認知症を防ぐための降圧療法2011

    • Author(s)
      森下竜一
    • Organizer
      第2回日本血管性認知障害研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-08-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      第34回日本神経科学大会(Neuroscience 2011)
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Increased Blood-Brain Barrier Vulnerability To Systemic Inflammation In Alzheimer Disease Mouse Model2011

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-10
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Dual Effects of a Statin on Abeta Metabolism: Up-regulation of Degradation of APP-CTF and Abeta Clearance2011

    • Author(s)
      Naoyuki Sato, Mitsuru Shinohara, Shuko Takeda, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance2011

    • Author(s)
      Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾2011

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZH EIMER DISEASE ANDDIABETES MELLITUS2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Grobal Alzheimer' s Research Summit
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Alteration in Plasma Beta-amyloid Levels after Glucose Loading Could Be a Novel Diagnostic Marker for Alzheimer Disease2011

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hisahiro Yu, Atsushi Moriguchi, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-09
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      第34回日本神経科学大会(Neuroscience2011)
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Alternation In Plasma Beta-Amyloid Levels After Glucose Loading Could Be A Novel Diagnostic Marker For Alzheimer Disease S.2011

    • Author(s)
      Takeda S, Sato N, Yu H, Moriguchi A, Uchio-Yamada K,Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 新規マイクロダイアリシス法開発とアルツハイマー病研究への応用2011

    • Author(s)
      里直行、武田朱公、樂木宏実、森下竜一
    • Organizer
      第15回日本心血管内分泌代謝学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Mechanistic Interaction Between Alzheimer Disease And Diabetes Mellitus : Analysis Of Novel Mouse Models Of Alzheimer Disease With Diabetes2011

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Grobal Alzheimer's Research Summit
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] PATHOLOGICAL INTERACTION BETWEEN ALZHEIMER DISEASE AND DIABETES MELLITUS2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Present and Future Alzheimer's Research / Grobal Alzheimer's Research Summit
    • Place of Presentation
      Madrid
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Mechanistic Interaction Between Alzheimer Disease And Diabetes Mellitus : Analysis Of Novel Mouse Models Of Alzheimer Disease With Diabetes2011

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病がアルツハイマー病の後天的危険因子である機序2011

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Alternation In Plasma Beta-Amyloid Levels After Glucose Loading Could Be A Novel Diagnostic Marker For Alzheimer Disease S.2011

    • Author(s)
      Takeda S, Sato N, Yu H, Moriguchi A, Uchio-Yamada K, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 認知症を防ぐための降圧療法2011

    • Author(s)
      森下竜一
    • Organizer
      第2回日本血管性認知障害研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-08-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Development of a novel microdialysis method to analyze molecules in brain interstitial fluid2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Kazuko Ikimura, Hirohito Nishino, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      第34回日本神経科学大会Neuroscience
    • Place of Presentation
      横浜
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病における血液脳関門の破綻による炎症の脳内への波及増幅2011

    • Author(s)
      里直行、武田朱公、樂木宏実、森下竜一
    • Organizer
      第34回日本高血圧学会総会
    • Place of Presentation
      宇都宮
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病における血液脳関門の破綻による炎症の脳内への波及増幅2011

    • Author(s)
      里直行、武田朱公、樂木宏実、森下竜一
    • Organizer
      第34回日本高血圧学会総会
    • Place of Presentation
      宇都宮
    • Year and Date
      2011-10-22
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 認知症を防ぐための降圧療法2011

    • Author(s)
      森下竜一
    • Organizer
      第2回日本血管性認知障害研究会
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-08-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      AAIC (Alzheimer Association International Conference)2011
    • Place of Presentation
      Paris
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Increased Blood-brain Barrier Vulnerability to Systemic Inflammation in Alzheimer Disease Mouse Model2011

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-10
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Dual Effects Of A Statin On Abeta Metabolism : Up-Regulation Of Degradation Of APP-CTF And Abeta Clearance2011

    • Author(s)
      Sato N, Shinohara M, Takeda S, Rakugi H, Morishita R.
    • Organizer
      The 10th International Conference on Alzheimer's & Parkinson's Diseases
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-12
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾2011

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、樂木宏実、森下竜一
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] CHANGE IN PLASMA BETA-AMYLOID LEVEL AFTER GLUCOSE LOADING : A POSSIBLE BIOMARKER FOR ALZHEIMER DISEASE2011

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Mari Ueda, Hisahiro Yu, Atsushi Moriguchi, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      AAIC (Alzheimer Association International Conference) 2011
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Mechanistic Interaction between Alzheimer Disease and Diabetes Mellitus: Analysis of Novel Mouse Models of Alzheimer Disease with Diabetes2011

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      The 10th International Conference on Alzheimer's and Parkinson's Diseases (ADPD 2011)
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2011-03-09
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Shinohara M, Rakugi H, Morishita R.
    • Organizer
      Alzheimer's Association International Conference on Alzheimer Disease 2010
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Increased brain vulnerability to systemic inflammation in Alzheimer disease transgenic mouse model2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      The 40th annual meeting of the Society for Neuroscience (Neuroscience 2010)
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 全身糖代謝が血中AB濃度に与える影響の検討:糖負荷後血中ABの変動を利用した新たなアルツハイマー病診断指標の探索2010

    • Author(s)
      武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
    • Organizer
      第52回日本老年医学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 糖尿病は脳血管障害と脳内インスリンシグナルの障害を介してアルツハイマー病脳内病態を修飾する2010

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
    • Organizer
      第10回日本抗加齢医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 糖代謝が血中B・アミロイド蛋白(AB)量に与える影響の検討:アルツハイマー病の新規診断指標への応用2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、湯久浩、守口篤、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病病態は末梢臓器でのインスリン抵抗性を増悪させることで糖尿病病態を増悪させる2010

    • Author(s)
      武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
    • Organizer
      第52回日本老年医学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アンジオテンシンII受容体拮抗薬はAβによる脳血管反応性障害を抑制しアルツハイマー病モデルマウスの認知機能障害を改善する2010

    • Author(s)
      武田朱公、里直行、荻原俊男、狩野方伸、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Model: Generation of Novel Transgenic Mouse Models of Alzheimer Disease with Diabetes2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension(ISH2010)
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 認知症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010

    • Author(s)
      里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Increased brain vulnerability to systemic inflammation in Alzheimer disease transgenic mouse model2010

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Organizer
      The 40th annual meeting of the Society for Neuroscience (Neuroscience 2010)
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Mechanistic interaction between Alzheimer disease and diabetes2010

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Organizer
      XXth World Congress of the International Society for Heart Research
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 全身糖代謝が血中Aβ濃度に与える影響の検討:糖負荷後血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索2010

    • Author(s)
      武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
    • Organizer
      第52回日本老年医学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖・エネルギー代謝が血中Abeta値に与える影響とその診断的応用2010

    • Author(s)
      武田朱公、里直行、湯久浩、守口篤、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Masanobu Kano, Toshio Ogihara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension(ISH2010)
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      Alzheimer's Association International Conference on Alzheimer Disease 2010(ICAD2010)
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アンジオテンシンII受容体拮抗薬はABによる脳血管反応性障害を抑制しアルツハイマー病モデルマウスの認知機能障害を改善する2010

    • Author(s)
      武田朱公、里直行、荻原俊男、狩野方伸、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease : Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010

    • Author(s)
      Sato N, Takeda S, Rakugi H, Morishita R.
    • Organizer
      AHA Scientific Sessions 2010
    • Place of Presentation
      Chicago, U.S.A.
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes accelerates memory dysfunction via cerebrovascular dysfunction in an Alzheimer mouse model with diabetes2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 認知症病棟入院患者の周辺症状に対する抑肝散、非定型抗精神病薬、アンジオテンシン受容体拮抗薬の効果の検討2010

    • Author(s)
      里直行、武田朱公、湯久浩、守口篤、楽木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖負荷による血中ABの変動を利用した新たなアルツハイマー病診断指標の探索:全身糖代謝が血中AB濃度に与える影響の検討2010

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
    • Organizer
      第10回日本抗加齢医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 新規マイクロダイアライシス回収システムによる脳内ペプチドin vivo測定系の開発2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010

    • Author(s)
      武田朱公、里直行、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease : Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010

    • Author(s)
      Sato N, Takeda S, Rakugi H, Morishita R.
    • Organizer
      AHA Scientific Sessions 2010
    • Place of Presentation
      Chicago, U.S.A.
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010

    • Author(s)
      Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R.
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 新規マイクロダイアライシス回収システムによる脳内ペプチドin vivo測定系の開発2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病とアルツハイマー病の相互的病態修飾機序の解明:糖尿病合併アルツハイマー病モデルマウスの作成とその病態解析2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第57回日本実験動物学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 糖代謝が血中β・アミロイド蛋白(Aβ)量に与える影響の検討:アルツハイマー病の新規診断指標への応用2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、湯久浩、守口篤、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Mechanistic interaction between Alzheimer disease and diabetes2010

    • Author(s)
      Takeda S, Sato N, Rakugi H, Morishita R.
    • Organizer
      XXth World Congress of the International Society for Heart Research
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖・エネルギー代謝が血中Abeta値に与える影響とその診断的応用2010

    • Author(s)
      武田朱公、里直行、湯久浩、守口篤、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病病態における血管性危険因子の役割:糖尿病合併アルツハイマー病モデルマウスの解析から:Role of vascular risk factors in the pathogenesis of Alzheimer disease : Analysis of novel mouse models of Alzheimer disease with diabete2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、篠原充、楽木宏実、森下竜一
    • Organizer
      Neuro 2010(第33回日本神経科学大会)
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes accelerates memory dysfunction via cerebrovascular dysfunction in an Alzheimer mouse model with diabetes2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] スタチンによるアルツハイマー病予防効果の機序の解明2010

    • Author(s)
      里直行、篠原充、島村宗尚、武田朱公、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾: Possible pathological interaction between diabetes mellitus and Alzheimer disease2010

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      Neuro 2010 (第33回日本神経科学大会)
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Possible Mutual Interaction Between Diabetes Mellitus and Alzheimer Disease: Generation of Novel Transgenic Mice Models of Alzheimer Disease With Diabetes2010

    • Author(s)
      Naoyuki Sato, Shuko Takeda, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      Microcirculation and Cerebral/Coronary/Peripheral Circulation, AHA Scientific Sessions 2010
    • Place of Presentation
      Chicago, U.S.A.
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖負荷による血中Aβの変動を利用した新たなアルツハイマー病診断指標の探索:全身糖代謝が血中Aβ濃度に与える影響の検討2010

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
    • Organizer
      第10回日本抗加齢医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病病態は末梢臓器でのインスリン抵抗性を増悪させることで糖尿病病態を増悪させる2010

    • Author(s)
      武田朱公、里直行、藤澤智巳、楽木宏実、森下竜一
    • Organizer
      第52回日本老年医学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-26
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 短期間の高カロリー食負荷はアルツハイマー病モデルマウスの認知機能障害を改善する2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 短期間の高カロリー食負荷はアルツハイマー病モデルマウスの認知機能障害を改善する2010

    • Author(s)
      武田朱公、里直行、樂木宏実、森下竜一
    • Organizer
      第21回日本老年医学会近畿地方会
    • Place of Presentation
      大阪
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病病態における血管性危険因子の役割:糖尿病合併アルツハイマー病モデルマウスの解析から:Role of vascular risk factors in the pathogenesis of Alzheimer disease : Analysis of novel mouse models of Alzheimer disease with diabete2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、篠原充、楽木宏実、森下竜一
    • Organizer
      Neuro 2010 (第33回日本神経科学大会)
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病における血管性危険因子による病態修飾機序の解明2010

    • Author(s)
      武田朱公、里直行、荻原俊夫、楽木宏実、森下竜一
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] HMG還元酵素阻害薬フルバスタチンのAβ代謝作用の解析2010

    • Author(s)
      篠原充、里直行、武田朱公、野間基子、森下竜一
    • Organizer
      第29回日本認知症学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Modle : Generation of Novel Transgenic Mouse Models of Alzheimer Disease wih Diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病における血管性危険因子による病態修飾機序の解明2010

    • Author(s)
      武田朱公、里直行、荻原俊夫、楽木宏実、森下竜一
    • Organizer
      第33回日本高血圧学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2010-10-17
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病合併アルツハイマー病モデルマウスにおける脳血管病態と脳内インスリンシグナルの変化2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第29回日本認知症学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] スタチンによるアルツハイマー病予防効果の機序の解明2010

    • Author(s)
      里直行、篠原充、島村宗尚、武田朱公、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] HMG還元酵素阻害薬フルバスタチンのAB代謝作用の解析2010

    • Author(s)
      篠原充、里直行、武田朱公、野間基子、森下竜一
    • Organizer
      第29回日本認知症学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾:Possible pathological interaction between diabetes mellitus and Alzheimer disease2010

    • Author(s)
      里直行、武田朱公、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      Neuro 2010(第33回日本神経科学大会)
    • Place of Presentation
      神戸(招待講演)
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病は脳血管障害と脳内インスリンシグナルの障害を介してアルツハイマー病脳内病態を修飾する2010

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、楽木宏実、森下竜一
    • Organizer
      第10回日本抗加齢医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-06-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes Accelerated Memory Dysfunction via Cerebrovascular Inflammation and Beta-Amyloid Deposition in Alzheimer Mouse Model : Generation of Novel Transgenic Mouse Models of Alzheimer Disease with Diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Rakugi H, Morishita R.
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-27
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 糖尿病合併アルツハイマー病モデルマウスにおける脳血管病態と脳内インスリンシグナルの変化2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第29回日本認知症学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Diabetes mellitus exacerbated learning impairment via cerebrovascular inflammation and disturbance of brain insulin signaling in Alzheimer mouse models with diabetes2010

    • Author(s)
      Takeda S, Sato N, Uchio-Yamada K, Sawada K, Kunieda T, Shinohara M, Rakugi H, Morishita R.
    • Organizer
      Alzheimer's Association International Conference on Alzheimer Disease 2010
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2010-07-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Angiotensin Receptor Blocker Prevented β-Amyloid-Induced Memory Impairment Associated with Recovery of Neurovascular Coupling2010

    • Author(s)
      Takeda S, Sato N, Kano M, Ogihara T, Rakugi H, Morishita R.
    • Organizer
      23rd Scientific Meeting of the International Society of Hypertension
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-09-28
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] Increased blood-brain barrier vulnerability to systemic inflammation in Alzheimer disease mouse model2010

    • Author(s)
      武田朱公、里直行、楽木宏実、森下竜一
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] 糖尿病とアルツハイマー病の相互的病態修飾機序の解明:糖尿病合併アルツハイマー病モデルマウスの作成とその病態解析2010

    • Author(s)
      武田朱公、里直行、内尾-山田こずえ、楽木宏実、森下竜一
    • Organizer
      第57回日本実験動物学会総会
    • Place of Presentation
      京都
    • Year and Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-22390145
  • [Presentation] アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明2009

    • Author(s)
      篠原充、里直行、栗波仁美、竹内大亮、武田朱公、野間基子、楽木宏美、森下竜一
    • Organizer
      第51回日本老年医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Fluvastatin (an HMG-CoA reductase inhibitor) reduces Abeta levels in brain by upregulating APP-CTFs degradation and Abeta clearance2009

    • Author(s)
      M.Shinohara, N.Sato, H.Kurinami, D.Takeuchi, S.Takeda, M.Noma, H.Rakugi, R.Morishita
    • Organizer
      Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Possible mutual interaction between diabetes mellitus and Alzheimer's disease : Generation of novel transgenic mice models of Alzheimer's disease with diabetic conditions2009

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, Ryuichi Morishita
    • Organizer
      ICAD (International Conference on Alzheimer's Disease) 2009
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2009-07-15
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 血糖状態及び血中インスリン値は血中Aβ量を修飾する:血中Aβ値のアルツハイマー病バイオマーカーとしての最適化条件の検討2009

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
    • Organizer
      第51回日本老年医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Fluvastatin(an HMG-CoA reductase inhibitor) reduces Aβlevels in brain by upregulating2009

    • Author(s)
      M. Shinohara, N. Sato, H. Kurinami, D. Takeuchi, S. Takeda, M. Noma, H. Rakugi, R. Morishita
    • Organizer
      APP-CTFs degradation and Aβclearance Nuroscience2009
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2009-10-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾機序の解明 : 新規病態合併モデル動物の作成とその解析2009

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、栗波仁美、竹内大亮、篠原充、楽木宏美、森下竜一
    • Organizer
      第51回日本老年医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] 血糖状態及び血中インスリン値は血中Aβ量を修飾する : 血中Aβ値のアルツハイマー病バイオマーカーとしての最適化条件の検討2009

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
    • Organizer
      第51回日本老年医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-19
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明2009

    • Author(s)
      篠原充、里直行、栗波仁美、竹内大亮、武田朱公、野間基子、楽木宏美、森下竜一
    • Organizer
      アルツハイマー病根本治療を目指したフルバスタチンの新規抗Aβ作用の解明
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] アルツハイマー病と糖尿病の相互的病態修飾機序の解明:新規病態合併モデル動物の作成とその解析2009

    • Author(s)
      武田朱公、里直行、内尾こずえ、澤田京子、國枝孝典、篠原充、栗波仁美、竹内大亮、楽木宏美、森下竜一
    • Organizer
      第51回日本老年医学会学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2009-06-18
    • Data Source
      KAKENHI-PROJECT-21659179
  • [Presentation] Possible mutual interaction between diabetes mellitus and Alzheimer' s disease : Generation of novel transgenic mice models of Alzheimer' s disease with diabetic conditions2009

    • Author(s)
      Shuko Takeda, Naoyuki Sato, Kozue Uchio-Yamada, Kyoko Sawada, Takanori Kunieda, Daisuke Takeuchi, Hitomi Kurinami, Mitsuru Shinohara, Hiromi Rakugi, and Ryuichi Morishita
    • Organizer
      ICAD(International Conference on Alzheimer' s Disease) 2009
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2009-07-15
    • Data Source
      KAKENHI-PROJECT-21659179
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