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Hibi Toshifumi  日比 紀文

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HIBI Toshifumi  日比 紀文

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Researcher Number 50129623
Other IDs
External Links
Affiliation (Current) 2025: 北里大学, 北里研究所病院, 特任教授
Affiliation (based on the past Project Information) *help 2013 – 2014: 慶應義塾大学, 医学部, 名誉教授
1996 – 2012: 慶應義塾大学, 医学部, 教授
2004 – 2005: 慶応義塾大学, 医学部, 教授
2000: 慶応義塾大学, 医学部, 教授
1999: 慶應義塾大学, 医学部, 内科教授 … More
1998: 慶應義塾大学, 医学部内科, 教授
1997: Keio University, School of Medicine, Professor, 医学部, 教授
1995: 慶応がんセンター, 助教授
1994: KEIO CANCER CENTER,ASSOCIATE PROFESSOR, 助教授
1994: 慶應義塾大学, 慶応がんセンター, 助教授
1993: 慶應義塾大学, がんセンター, 助教授
1992: Keio Cancer Center, 診療部長
1991: 慶応ガンセンター, 部長
1986 – 1987: 北里研究所, 病院内科, 医長 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology / Biological Sciences
Except Principal Investigator
Gastroenterology / Gastroenterology / Neurology / Applied pharmacology / 広領域 / Immunology
Keywords
Principal Investigator
炎症性腸疾患 / IL-7 / musashi-1 / 腸管免疫 / inflammatory bowel disease / 幹細胞 / 大腸癌 / サイトカイン / トランスジェニックマウス / mucosal immunology … More / 粘膜再生療法 / SP細胞 / 腸管上皮 / 潰瘍性大腸炎 / ノックアウトマウス / IL-7レセプター / regeneration of mucosa / stem cell / intestinal epithelial cell / T lymphocytes / knock-out mice / cytokine / transgenic mice / interleukin-7 receptor / interleukin-7 / HIV / WNT / β-catenin / Wntシグナル / side population cell / in vivo tissue staining / LHK antibody / plasma / biomagnetic probe / liposome / heme / colon cancer / バイオマグネティックプローブ / 生体内組織染色 / プラズマ / ヘム / 磁性体 / リポソーム / Cholera toxin / cytotoxic Tlymphcyte / transgenic mouse / oral Immunization / AIDS / SIV / コレラトキシン / 細胞障害性T細胞 / 経口免疫 / エイズ / fibrocyte / 腸管線維化 / クローン病 / 大腸がん / 下部消化管 / 下部消化管学 / 生物学的製剤 / 分指標的 / フェライト粒子 / 免疫記憶 / NK細胞 / 腸内細菌 / マクロファージ / dysplasia / ELISA / p53 / サーベイランス / GFP / ジフテリア毒素 / drug delivery system / ヒト第6番染色体 / 欠失地図 … More
Except Principal Investigator
炎症性腸疾患 / inflammatory bowel disease / 潰瘍性大腸炎 / Th1 / Crohn's disease / IgG Fc binding protein / Crohn病 / 腸管免疫 / 大腸癌 / 自然免疫 / クローン病 / 腸内細菌 / HIV / Cbl-b / B7h / bone marrow transplantation / transdifferentiation / cell fusion / 制御性T細胞 / drug delivery system / SAP / Th2 / intestinal microflora / モデルマウス / フローラ / DNA / mucin / mucosal defense / ムチン / 粘膜防御 / immunology / 樹状細胞 / トランスレーショナルリサーチ / 生体分子 / 腸内フローラ / 免疫学 / mucosal immunology / トランスジェニックマウス / antigen / 抗原 / 抗体 / ハイパーサーミア / 抗ガン剤 / CD4 / ulcerative colitis / AIDS / cDNA / retrovirus / thymus / myasthenia graves / 逆転写酵素 / HTLV / ウイルス遺伝子のクローニング / cNDA / レトロウイルス / 胸腺 / 重症筋無力症 / DSS coliti / interleulcin-10 gene deficient mice / Germ-free / 慢性腸炎 / DSS腸炎 / IL-10ノックアウトマウス / immunoregulatory therapy / CD8 T cell / homeostasis / regulatory T cell / epithelial cell / Cb1-b / 抑制性CD8^+T細胞 / ホメオスタシス / 免疫統御療法 / 抑制性CD8T細胞 / ホメオシタシス / 大腸上皮 / bonemarrow transplantation / translational research / biological molecule / intestinal bacteria / プロバイオティクス / マウス大腸炎モデル / メモリー細胞 / 細菌 / 粘膜制御 / T cell / IBD / T細胞 / natural killer T cell / dendritic cell / NKT細胞 / stem cell / disease model mice / NOG mice / 幹細胞 / NOGマウス / Transgenic mice / Cell transfer / Probiotics / Ulcerative colitis / Antigen-specific / murine model / inflammatory bowel diseases / 自己免疫疾患 / 慢性大腸炎モデル / 単クローン / 腸管粘膜免疫 / 調節製T細胞 / 慢性大腸炎 / 調節性T細胞 / 細胞移入 / プロバイオテクス / 抗原特異性 / マウスモデル / Ferrite nanobeads / Anticancer drug / Hyperthermia / MRI contrast agent / Bio-sensing / Bio-screening / Magnetic beads / CEA抗体 / IgG抗体 / フェライトナノビーズ / MMI造影 / GMA / フェライト粒子 / MRI造影剤 / DNA検出 / 磁性ビーズ / フェライト・ナノビーズ / MRI造影 / バイオセンシング / バイオスクリーニング / 磁気ビーズ / intestinal mucosal immunology / isolated lymphoid follicles / cryptopatch / secretory IgA antibody / intestinal T cells / γδ T cells / intestinal flora / dietary substances / 一酸化炭素 / Heme oxygenase / インターロイキン15 / 腸管上皮細胞 / 腸内常在フローラ / 分泌型lgA抗体 / 腸管孤立リンパ小節 / 腸管上皮細胞間T細胞 / 経口免疫寛容 / 孤立リンパ小節 / クリプトパッチ / 分泌型IgA抗体 / 腸管上皮細胞T細胞 / γδT細胞 / 食品 / GTP-bindinK protein / Rho-fatnily GTPases / Racl / metastasis / colon cancer / GTP結合タンパク質 / Rhoファミリー / Rac1 / 転移 / diphteria toxin / T lymphocytes / knock-out mice / interleukin-7 receptor / interleukin-7 / ノックアウトマウス / ジフテリア毒素 / IL-7レセプター / IL-7 / antibody / magnetic bioprobe / hyperthermia / anticancer drug / IGG antibody / ferrite beads / medical magnetic beads / 磁気分離 / 生体高分子 / CMC / BSA / スピネル型 / バイオ高分子 / バイオ・リガンド / マグネタイト / 蛍光磁性プローブ / 磁性バイオプローブ / IGG抗体 / フェライト超微粒子 / 医用磁性ビーズ / LASER / early colon cancer / autofluolescence / 異型上皮 / 自然蛍光 / レーザー / SOLUBLE CD4 / MONOCLONAL ANTIBODY / CYTOTOXIC T LYMPHOCYTE / INTESTINAL MUCOSAL LYMPHOCYTE / 腸管上皮間リンパ球 / 可溶性CD4 / モノクローナル抗体 / 細胞障害性T細胞 / 腸管粘膜内リンパ球 / エイズ / animal model of colitis / hapten / Crhon's disease / 大腸特異抗原 / 実験腸炎 / 実験大腸炎 / ハプテン / 内視鏡 / 清瘍性大腸炎 / 早期発見 / 内神鏡 / dysplasia / p53 / ELISA / サーベイランス / 細胞内寄生菌 / オートファジー / マクロファージ / 粘膜免疫 / 癌関連遺伝子 / 腸管上皮再生 / 細胞接着 / 大腸癌転移 / 腸管上皮分化 / 消化器学(食道、胃、小腸、大腸) / 免疫抑制剤 / TPMT遺伝子多型 / 腸管粘膜防御機構 / IgGFcレセプター / CTL / 経口ワクチン / SIV Less
  • Research Projects

    (40 results)
  • Research Products

    (314 results)
  • Co-Researchers

    (53 People)
  •  Molecular characterization of Colitis Associated CancerPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  The role of fibrocyte in intestinal fibrosis and screening of anti-fibrotic therapy targeting fibrocyte.Principal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  特異抗体結合フェライトスーパービーズによる免疫標的療法の創成Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Investigation of intestinal macrophage in contribution to gut immune homeostasis and its disruption in Crohn's diseasePrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel disease

    • Principal Investigator
      INOUE Nagamu
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
    • Research Field
      Immunology
    • Research Institution
      Keio University
  •  Establishment of cancer surveillance using serum anti-p53 antibody in patients with ulcerative colitis

    • Principal Investigator
      IWAO Yasushi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Analysis of intestinal epithelial differentiation and mechanisms of colon cancer metastasis in Cdx-induced human Colo 205 cells

    • Principal Investigator
      EZAKI Toshihiko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  潰瘍性大腸炎合併大腸癌に対する新しいサーベイランス法の確立-抗p53抗体の有用性Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  The establishment of bacteria antigen-specific T cell transgenic mice develop spontaneous chronic colitis, and the development of inhibitory probiotics for the treatment of inflammatory bowel diseases

    • Principal Investigator
      KANAI Takanori
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  The role of bone marrow-derived cells in generation of gut epithelium

    • Principal Investigator
      YAJIMA Tomoharu
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  The maintenance of mucosal homeostasis by regulating functional B7h on the colonic epithelial cells and development a cure for inflammatory bowel disease.

    • Principal Investigator
      NAKAZAWA Stsushi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  Involvement of intestinal flora in the pathogenesis of chronic'colitis

    • Principal Investigator
      INOUE Nagamu
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Identification of gastrointestinal epithelial stem cell and development of regeneration therapy for LBDPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  Exploitation of a novel therapy for inflammatory bowel diseases by modulating SAP, a T cell specific adaptor molecule

    • Principal Investigator
      OKAMOTO Susumu
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Novel therapeutic strategy for ulcerative colitis by hard capsule contained with IgG Fc binding protein

    • Principal Investigator
      OGATA Haruhiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  腸管上皮幹細胞の純化と炎症性腸疾患に対する新しい再生治療の開発Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Keio University
  •  Applying ferrite nanobeads to medical diagnosis, therapy and analysis

    • Principal Investigator
      ABE Masanori
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied pharmacology
    • Research Institution
      Tokyo Institute of Technology
  •  Establishment of transgenic mice that recognize bacteria specific antigen and develop spontaneous colitis under specific pathogen free condition.

    • Principal Investigator
      KANAI Takanori
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of novel mouse model of human Crohn's disease

    • Principal Investigator
      INOUE Nagamu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Development of novel therapy targeting dendritic cells for Crohn's disease

    • Principal Investigator
      IWAO Yasushi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  遺伝子組換えフローラ大腸菌含有ハードカプセルを用いた漫性大腸炎に対する治療戦略Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Identification of gastrointestinal epithelial stem cell and development of regeneration therapy for IBDPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Distribution and characterization of IgG Fc binding protein in various mucin producing cells

    • Principal Investigator
      OGATA Haruhiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  遺伝子多型性の解析に基づいた炎症性腸疾患に対する新しい免疫抑制剤投与法の開発

    • Principal Investigator
      NAGANUMA Makoto
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  炎症を発生母地とした大腸癌に関与する新規癌抑制遺伝子の単離Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Regulation of the cancer cell motility by Racl GTPase: implications for metastasis of colon cancer

    • Principal Investigator
      NAKANO Masaru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      TOKYO DENTAL COLLEGE
  •  Investigation of immuno-regulatory competency of dietary substances and its application for our own beneficial ends

    • Principal Investigator
      ISHIKAWA Hiromichi
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Keio University
  •  Magnetic probe with ferrite couples to bioligands for diagnostic and clinical uses

    • Principal Investigator
      ABE Masanori
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      Tokyo Institute of Technology
  •  New therapy targeting IL-7 receptor positive lymphocytes for chronic intestinal inflammation

    • Principal Investigator
      NAGANUMA Makoto
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Development of novel diagnostic device using lesion-orieinted biomagnetic probePrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  腸管粘膜内IL-7レセプター腸性細胞を標的とした新しい慢性大腸炎治療法の開発Principal Investigator

    • Principal Investigator
      日比 紀文
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  New therapy for chronic intestinal inflammation by regulating mucosal immune responsesPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  New therapy for intestinal inflammation by regulating mucosal immune responsesPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  腸管粘膜防御機構における腸管上皮細胞IgGFcレセプター(結合蛋白)の解析

    • Principal Investigator
      田原 利行
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  経口ワクチン開発のための腸管内HIV特異的細胞傷害性T細胞に関する基礎的研究

    • Principal Investigator
      KANAI Takanori
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Detection of neoplastic lesion and dysplasia using laser beam under the endoscope

    • Principal Investigator
      IWAO .yasushi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Induction of cytotoxic Tlymphocyters in the intestinal mucosa by oral immunization of SIV gag or env peptide conjugated with chorela toxinPrincipal Investigator

    • Principal Investigator
      HIBI Toshifumi, 渡辺 守
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  ACTIVE IMMUNE THERAPY FOR THE TREATMENT OF AIDS

    • Principal Investigator
      WATANABE Mamoru
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      KEIO UNIVERSITY
  •  Investigations of immunological disturbance in ulcerative colitis and animal models of inflammatory bowel disease.

    • Principal Investigator
      TSUCHIMOTO Kanji
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      KITASATO INSTITUTE
  •  Research for retroviruses in thymus cells of myasthenia gravis and their involvement in the pathogeneses of myasthenia gravis

    • Principal Investigator
      ONO Kairo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      The Kitassto Institute

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] ドクターサロン 実地診療における炎症性腸疾患2014

    • Author(s)
      日比紀文
    • Publisher
      杏文堂
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] 内科 潰瘍性大腸炎2014

    • Author(s)
      日比紀文、小林拓、中野雅
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] INTESTINE 大腸内視鏡(4)超拡大内視鏡2014

    • Author(s)
      小林拓、長沼誠、緒方晴彦、日比紀文、金井隆典
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] G.I.Research わたしの研究歴2014

    • Author(s)
      日比紀文
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] 日本成人病(生活習慣病)学会準機関誌 潰瘍性大腸炎の内科治療-近年の変化2014

    • Author(s)
      日比紀文、小林拓、中野雅
    • Publisher
      日本成人病(生活習慣病)学会
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] INTESTINE 特集「日常遭遇する大腸炎の鑑別-内視鏡を中心に」「序説」2014

    • Author(s)
      日比紀文
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] 薬局 潰瘍性大腸炎(エキスパートに学ぶ!薬物治療における直腸投与製剤の位置づけと活用のポイント①)2014

    • Author(s)
      日比紀文、小林拓、中野雅、渡辺憲明
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] INTESTINE 特集 腸管ベーチェット病と単純性潰瘍 腸管ベーチェット病の治療-改訂コンセンサスを中心に2014

    • Author(s)
      久松 理一、上野 文昭、日比 紀文
    • Publisher
      日本メディカルセンター
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] IBD Research IBD診療に使用されるインデックスの今後の展望2014

    • Author(s)
      小林拓、筋野智久、加藤裕佳子、中野雅、日比紀文
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] Rheumatology Clinical Research 特集 生物学的製剤の適応があるリウマチ類縁疾患 炎症性腸疾患2014

    • Author(s)
      日比紀文 小林拓 中野雅
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Book] 炎症性腸疾患2012

    • Author(s)
      久松理一、日比紀文
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] G.I.Research IBDと炎症性サイトカイン-Th17-2011

    • Author(s)
      久松理一、日比紀文
    • Publisher
      先端医学社
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] 潰瘍性大腸炎消化器疾患ガイドライン2011

    • Author(s)
      久松理一、日比紀文
    • Publisher
      総合医学社
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療2010

    • Author(s)
      日比紀文、久松理一
    • Total Pages
      213
    • Publisher
      羊土社出版
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療2010

    • Author(s)
      日比紀文、久松理一
    • Total Pages
      340
    • Publisher
      医学書院出版
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] 炎症性腸疾患の鑑別診断(日比紀文編)(炎症性腸疾患)2010

    • Author(s)
      日比紀文
    • Total Pages
      340
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療(久松理一、日比紀文編)2010

    • Author(s)
      日比紀文
    • Total Pages
      213
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression2014

    • Author(s)
      Nakamura S, Yaguchi T, Kawamura N, Kobayashi A, Sakurai T, Higuchi H, Takaishi H, Hibi T, Kawakami Y
    • Journal Title

      J Immunother

      Volume: 37(2) Issue: 2 Pages: 63-72

    • DOI

      10.1097/cji.0000000000000011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24591635, KAKENHI-PROJECT-25830122
  • [Journal Article] A large-scale,prospective,observational study of leukocytapheresis for ulcerative colitis:treatment outcomes of 847 patients in clinical practice2014

    • Author(s)
      Yokoyama Y, Matsuoka K, Kobayashi T, Sawada K, Fujiyoshi T, Ando T, Ohnishi Y, Ishida T, Oka M, Yamada M, Nakamura T, Ino T, Numata T, Aoki H, Sakou J, Kusada M, Maekawa T, Hibi T.
    • Journal Title

      Journal of Crohn's and Colitis

      Volume: 8 Issue: 9 Pages: 981-91

    • DOI

      10.1016/j.crohns.2014.01.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice2014

    • Author(s)
      Tomita, K. Teratani, T. Suzuki, T. Shimizu, M. Sato, H. Narimatsu, K. Okada, Y. Kurihara, C. Irie, R. Yokoyama, H. Shimamura, K. Usui, S. Ebinuma, H. Saito, H. Watanabe, C. Komoto, S. Kawaguchi, A. Nagao, S. Sugiyama, K. Hokari, R. Kanai, T. Miura, S. Hibi, T.
    • Journal Title

      Hepatology

      Volume: 59 Issue: 1 Pages: 154-169

    • DOI

      10.1002/hep.26604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-24790719
  • [Journal Article] The 2nd edition of consensus statements for the diagnosis and management of intestinal Behcet's disease: indication of anti-TNFα monoclonal antibodies.2014

    • Author(s)
      Hisamatsu T, Ueno F, Matsumoto T, Kobayashi K, Koganei K, Kunisaki R, Hirai F,Nagahori M, Matsushita M, Kobayashi K, Kishimoto M, Takeno M, Tanaka M, Inoue N, Hibi T.
    • Journal Title

      J Gastroenterol

      Volume: 49(1) Issue: 1 Pages: 156-62

    • DOI

      10.1007/s00535-013-0872-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591443, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-26461469
  • [Journal Article] Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predjspose the liver to inflammation.2014

    • Author(s)
      Mikami Y, Mizuno S, Nakamoto N, Hayashi A, Sujino T, Sato T, Kamada N, Matsuoka K, Hisamatsu T, Ebinuma H, Hibi T, Yoshimura A, Kanai T.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 1 Pages: 1-1

    • DOI

      10.1371/journal.pone.0084619

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
  • [Journal Article] Use of capsule endoscopy in patients with Crohn's disease in Japan: a multicenter survey.2014

    • Author(s)
      Esaki M, Matsumoto T, Watanabe K, Arakawa T, Naito Y, Matsuura M, Nakase H, Hibi T, Matsumoto T, Nouda S, Higuchi K, Ohmiya N, Goto H, Kurokawa S, Motoya S, Watanabe M.
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 29(1) Issue: 1 Pages: 96-101

    • DOI

      10.1111/jgh.12411

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590941
  • [Journal Article] Surveillance using trimodal imaging endoscopy after endoscopic submucosal dissection for superficial gastric neoplasia.2014

    • Author(s)
      Imaeda H, Hosoe N, Kashiwagi K, Ida Y, Nakamura R, Suzuki H, Saito Y, Yahagi N, Iwao Y, Kitagawa Y, Hibi T, Ogata H, Kanai T.
    • Journal Title

      World Journal of Gastroenterology

      Volume: 20(43) Issue: 43 Pages: 16311-7

    • DOI

      10.3748/wjg.v20.i43.16311

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-26670065
  • [Journal Article] Efficacy and safety of adalimumab in Japanese patients with moderately to severely active ulcerative colitis.2014

    • Author(s)
      Suzuki Y,Motoya S,Hanai H,Matsumoto T,Hibi T,Robinson AM,Mostafa NM,Chao J,Arora V,Camez A,Thakkar RB,Watanabe M.
    • Journal Title

      J Gastroenterol

      Volume: 49 Issue: 2 Pages: 283-94

    • DOI

      10.1007/s00535-013-0922-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis2014

    • Author(s)
      Usui S, Hosoe N, Matsuoka K, Kobayashi T, Nakano M, Naganuma M, Ishibashi Y, Kimura K, Yoneno K, Kashiwagi K, Hisamatsu T, Inoue N, Serizawa H, Hibi T, Ogata H, Kanai T.
    • Journal Title

      Digestive Endoscopy

      Volume: 26(5) Issue: 5 Pages: 665-72

    • DOI

      10.1111/den.12269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25460960
  • [Journal Article] Endoscopic imaging of parasites in the human digestive tract.2014

    • Author(s)
      Hosoe N, Ogata H, Hibi T.
    • Journal Title

      Parasitol Int

      Volume: 63(1) Issue: 1 Pages: 216-20

    • DOI

      10.1016/j.parint.2013.08.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis.2013

    • Author(s)
      Sandborn WJ, Feagan BG, Marano C, Zhang H, Strauss R, Johanns J, Adedokun OJ, Guzzo C, Colombel JF, Reinisch W, Gibson PR, Collins J, Järnerot G, Hibi T, Rutgeerts P; PURSUIT-SC Study Group.
    • Journal Title

      Gastroenterology

      Volume: 146(1) Issue: 1 Pages: 85-95

    • DOI

      10.1053/j.gastro.2013.05.048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain- containing m-Numb protein expression in regenerating gastric mucosa.2013

    • Author(s)
      Tetsufumi Takahashi
    • Journal Title

      PLoS One

      Volume: 8 Issue: 1 Pages: 1-13

    • DOI

      10.1371/journal.pone.0053540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-22600011, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178
  • [Journal Article] TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.2013

    • Author(s)
      Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T.
    • Journal Title

      Immunology

      Volume: 139(1) Issue: 1 Pages: 19-29

    • DOI

      10.1111/imm.12045

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
  • [Journal Article] A Single Strain of Clostridium butyricum Induces Intestinal I L-10-Producing Macrophages to Suppress Acute Exlperimental Colitis in Mice.2013

    • Author(s)
      Hayashi A, Sato T, Kamada N, Mikami Y, Matsuoka K, Hisamatsu T, Hlbi T, Roers A, Yagita H, Ohteki T, Yoshimura A, Kanai T.
    • Journal Title

      Cell Host Microbe

      Volume: 13 Issue: 6 Pages: 711-22

    • DOI

      10.1016/j.chom.2013.05.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
  • [Journal Article] CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion2013

    • Author(s)
      Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] C-reactive protein is an indicator of serum infliximab level in predicting loss of response in patients with Crohn's disease.2013

    • Author(s)
      Hibi T, Sakuraba A, Watanabe M, Motoya S, Ito H, Sato N, Yoshinari T, Motegi K, Kinouchi Y, Takazoe M, Suzuki Y, Matsumoto T, Kawakami K, Matsumoto T, Hirata I, Tanaka S, Ashida T, Matsui T.
    • Journal Title

      J Gastroenterol.

      Volume: 49(2) Issue: 2 Pages: 254-62

    • DOI

      10.1007/s00535-013-0807-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice2013

    • Author(s)
      Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T.
    • Journal Title

      Immunol Lett.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin.2013

    • Author(s)
      Takabayashi K, Kashiwagi K, Kawata T, Sato T, Matsuoka K, Hisamatsu T, Takaishi H, Hibi T, Ogata H, Yahagi N, Kitagawa Y, Shigematsu N, Kanai T.
    • Journal Title

      Cancer Biol Ther.

      Volume: 15(1) Issue: 1 Pages: 81-8

    • DOI

      10.4161/cbt.26610

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
  • [Journal Article] Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients.2013

    • Author(s)
      Miyoshi J, Matsuoka K, Inoue N, Hisamatsu T, Ichikawa R, Yajima T, Okamoto S, Naganuma M, Sato T, Kanai T, Ogata H, Iwao Y, Hibi
    • Journal Title

      J Crohns Colitis

      Volume: 7 Issue: 12 Pages: e609-e614

    • DOI

      10.1016/j.crohns.2013.04.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
  • [Journal Article] Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice.2013

    • Author(s)
      Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi. A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T.
    • Journal Title

      Immunology Letters

      Volume: 150 Issue: 1-2 Pages: 123-9

    • DOI

      10.1016/j.imlet.2013.01.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
  • [Journal Article] IL-22-Producing RORyt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis.2013

    • Author(s)
      Matsumoto A, Kanai T, Mikami Y, Chu PS, Nakamoto N, Ebinuma H, Saito H, Sato T, Yagita H, Hibi T.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 4 Pages: e62853-e62853

    • DOI

      10.1371/journal.pone.0062853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
  • [Journal Article] C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.2013

    • Author(s)
      Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito H, Hibi T.
    • Journal Title

      Hepatology

      Volume: 58 Issue: 1 Pages: 337-350

    • DOI

      10.1002/hep.26351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046
  • [Journal Article] CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.2013

    • Author(s)
      Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 304 Issue: 8 Pages: G700-G707

    • DOI

      10.1152/ajpgi.00318.2012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-24659374
  • [Journal Article] Efficacy and tolerability of oral budesonide in Japanese patients with active Crohn's disease: a multicentre, double-blind, randomized, parallel-group Phase II study2013

    • Author(s)
      Suzuki Y, Motoya S, Takazoe M, Kosaka T, Date M, Nii M, Hibi T.
    • Journal Title

      J Crohns Colitis

      Volume: 7(3) Issue: 3 Pages: 239-47

    • DOI

      10.1016/j.crohns.2012.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Journal Article] Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway2012

    • Author(s)
      Ichikawa R, Hisamatsu T, Hibi T, et al.
    • Journal Title

      Immunology

      Volume: 136(2) Pages: 153-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14+ macrophage activation2012

    • Author(s)
      Uo M, Hisamatsu T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K,Matsuoka K, Kanai T, Hibi T
    • Journal Title

      Gut.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells.2012

    • Author(s)
      Nishida A, Nagahama K, Imaeda H, Ogawa A, Lau CW, Kobayashi T, Hisamatsu T, Preffer FI, Mizoguchi E, Ikeuchi H, Hibi T, Fukuda M, Andoh A, Blumberg RS, Mizoguchi A.
    • Journal Title

      J Exp Med.

      Volume: 209(13) Issue: 13 Pages: 2383-94

    • DOI

      10.1084/jem.20112631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24790852
  • [Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice.2012

    • Author(s)
      Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T.
    • Journal Title

      Gastroenterology

      Volume: 143 Issue: 5 Pages: 1288-1297

    • DOI

      10.1053/j.gastro.2012.07.108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-22590763, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375
  • [Journal Article] Activated Hepatic Stellate Cells Mediate the Differentiation of Macrophages.2012

    • Author(s)
      Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, and Hibi T.
    • Journal Title

      Hepatology Research.

      Volume: Epub ahead of print Issue: 6 Pages: 658-669

    • DOI

      10.1111/j.1872-034x.2012.01111.x

    • NAID

      10031194568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Anticoagulation therapy dramatically improved severe sigmoiditis with findings resembling inflammatory bowel disease, which was caused by mesenteric venous thrombosis.2012

    • Author(s)
      Mikami Y, Kanai T, Iwasaki E, Naganuma M, Yamagishi Y, Shimoda M, Matsuoka K, Hisamatsu T, Iwao Y, Ogata H, Nakatsuka S, Mukai M, Hibi T.
    • Journal Title

      Clinical Journal of Gastroenterology.

      Volume: 5 Pages: 377-382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Immune aspects of the pathogenesis of inflammatory bowel disease.2012

    • Author(s)
      Hisamatsu T, Kanai T, Mikami Y, Yoneno K, Matsuoka K, Hibi T.
    • Journal Title

      Pharmacology & Therapeutics

      Volume: 137 Issue: 3 Pages: 283-297

    • DOI

      10.1016/j.pharmthera.2012.10.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-24659374
  • [Journal Article] Dysregulated balance of retinoid-related orphan receptor _Yt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis.2012

    • Author(s)
      Kimura K, Kanai T, Hayashi A, Mikami Y, Sujino T, Mizuno S, Handa T, Matsuoka K, Hisamatsu T, Sato T, Hibi T.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 427 Issue: 4 Pages: 694-700

    • DOI

      10.1016/j.bbrc.2012.09.091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PROJECT-24659374
  • [Journal Article] Is the dendritic cell a missing piece in the pathogenesis model of post-infectious irritable bowel syndrome?-Editorial for "Characteristics of intestinal lamina propria dendritic cells in a mouse model of postinfectious irritable bowel syndrome.2012

    • Author(s)
      Hisamatsu T, Hibi T
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: 27 Pages: 847-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14+ macrophage activation.2012

    • Author(s)
      Uo M, Hisamatsu T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K,Matsuoka K, Kanai T, Hibi T.
    • Journal Title

      Gut.

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Immune aspects of the pathogenesis of inflammatory bowel disease2012

    • Author(s)
      Hisamatsu T, Kanai T, Yohei Mikami, Yoneno K, Matsuoka K, Hibi T
    • Journal Title

      Pharmacol Ther.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] A Case of Intestinal Behçet's Disease Treated with Infliximab Monotherapy Who Successfully Maintained Clinical Remission and Complete Mucosal Healing for Six Years.2012

    • Author(s)
      Maruyama Y, Hisamatsu T, Matsuoka K, Naganuma M, Inoue N, Ogata H, Iwao Y, Kanai T, Hibi T.
    • Journal Title

      Intern Med.

      Volume: 51(16) Pages: 2125-9

    • NAID

      130002062319

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice2012

    • Author(s)
      Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T .
    • Journal Title

      Gastroenterology.

      Volume: 143 Pages: 1288-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Dysregulated balance of retinoid-related orphan receptor γt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis2012

    • Author(s)
      Kimura K, Kanai T, Hayashi A, Mikami Y, Sujino T, Mizuno S, Handa T, Matsuoka K, Hisamatsu T, Sato T Hibi T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 427 Pages: 694-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] A Case of Intestinal Behcet's Disease Treated with Infliximab Monotherapy Who Successfully Maintained Clinical Remission and Complete Mucosal Healing for Six Years2012

    • Author(s)
      Maruyama Y, Hisamatsu T, Matsuoka K, Naganuma M, Inoue N, Ogata H, Iwao Y, Kanai T, Hibi T
    • Journal Title

      Intern Med

      Volume: 51 Pages: 2125-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells2011

    • Author(s)
      Sujino T, Kanai T, Hisamatsu T, Hibi T, et al.
    • Journal Title

      Gastroenterology

      Volume: 141(3) Pages: 1014-1023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 総説『クローン病の長期予後について考える』2011

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      日本消化器病学会雑誌

      Volume: 108巻3号 Pages: 373-380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 炎症性腸疾患におけるアミノ酸補給の意義2011

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      日本消化吸収学会雑誌

      Volume: 33(3) Pages: 352-361

    • NAID

      10029066191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis.2011

    • Author(s)
      Kawamata S, Matsuzaki K, Murata M, Seki T, Matsuoka K, Iwao Y, Hibi T, Okazaki K
    • Journal Title

      Inflamm Bowel Dis 17(3)

      Pages: 683-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] 特集:小腸疾患:診断と治療の進歩II.診療の進歩6.Crohn病2011

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      日本内科学会雑誌

      Volume: 第100巻第1号 Pages: 85-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011

    • Author(s)
      Miyoshi J, Hisamatsu T, Kanai T, Hibi T, et al.
    • Journal Title

      J Gastroenterol

      Volume: 46(9) Pages: 1056-1063

    • NAID

      10029706720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 特集:小腸疾患:診断と治療の進歩II.診療の進歩62011

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      Crohn病日本内科学会雑誌

      Volume: 第100巻第1号 Pages: 85-95

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages.2011

    • Author(s)
      Naruse H, Hisamatsu T, Yamauchi Y, Chang JE, Matsuoka K, Kitazume MT, Arai K, Ando S, Kanai T, Kamada N, Hibi T.
    • Journal Title

      Clin Exp Immunol.

      Volume: Feb24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Successful treatment of a large hyperplastic polyp in the jejunum by using single-balloon enteroscopy.2011

    • Author(s)
      Nakamura S, Imaeda H, Sujino T, Hosoe N, Naganuma M, Ebinuma H, Okamoto S, Nishizawa T, Takahashi M, Iwao Y, Kameyama K, Mukai M, Ogata H, Hibi T.
    • Journal Title

      Gastrointest Endosc.

      Volume: (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity2011

    • Author(s)
      Kobayashi T, Hisamatsu T, Hibi T, Rothman PB, Kashiwada M
    • Journal Title

      J Immunol

      Volume: 186(8) Pages: 4649-4655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages Clin Exp Immunol2011

    • Author(s)
      Naruse H, Hisamatsu T, Kanai T, Hibi T, et al.
    • Volume
      164(1)
    • Pages
      137-144
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Rothman PB, Kashiwada M, Plevy SE.NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity2011

    • Author(s)
      Kobayashi T, Hisamatsu T, Hibi T, et al, 他8名、11番目
    • Journal Title

      J Immunol

      Volume: 186(8) Pages: 4649-4655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] ヒト腸管自然免疫担当細胞による恒常性維持と炎症性腸疾患におけるその破綻2011

    • Author(s)
      久松理一、鎌田信彦、日比紀文
    • Journal Title

      細胞工学(監修清野宏)(秀潤社)

      Volume: Vol.30 No.4 Pages: 366-370

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 炎症性腸疾患におけるアミノ酸補給の意義2011

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      日本消化吸収学会雑誌総説

      Volume: (in press)

    • NAID

      10029066191

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] ヒト腸管自然免疫担当細胞による恒常性維持と炎症性腸疾患におけるその破綻2011

    • Author(s)
      久松理一、鎌田信彦、日比紀文
    • Journal Title

      細胞工学監修清野宏秀潤社

      Volume: Vol.30 No.4 Pages: 366-370

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages2011

    • Author(s)
      Naruse H, Hisamatsu T, Kanai T, Hibi T, et al, 他7名、11番目
    • Journal Title

      Clin Exp Immunol

      Volume: 164(1) Pages: 137-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial.2011

    • Author(s)
      Watanabe T, Ajioka Y, Matsumoto T, Tomotsugu N, Takebayashi T, Inoue E, Iizuka B, Igarashi M, Iwao Y, Ohtsuka K, Kudo SE, Kobayashi K, Sada M, Matsumoto T, Hirata I, Murakami K, Nagahori M, Watanabe K, Hida N, Ueno F, Tanaka S, Watanabe M, Hibi T
    • Journal Title

      J Gastroenterol 46Suppl 1

      Pages: 11-6

    • NAID

      10029029994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] 特集:生体防御と自然免疫-最近の知見Workshop実臨床のトピックスIBD発症進展における自然免疫の役割2010

    • Author(s)
      久松理一, 日比紀文
    • Journal Title

      侵襲と免疫 メジカルビュー社

      Volume: Vol.19 No.2 Pages: 39-42

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Clinical results of observation of the upper gastrointestinal tract by transgastrostomic endoscopy using an ultrathin endoscope.2010

    • Author(s)
      Imaeda H, Hosoe N, Nakamizo H, Kashiwagi K, Suzuki H, Saito Y, Suganuma K, Ida Y, Matsuzaki J, Iwasaki E, Iwao Y, Ogata H, Hibi T.
    • Journal Title

      J Gastroenterol Hepatol.

      Volume: 25 Pages: 1850-1854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010

    • Author(s)
      Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
    • Journal Title

      J Immunol

      Volume: 184(5) Pages: 2671-2676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010

    • Author(s)
      Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T
    • Journal Title

      Eur J Immunol 40(9)

      Pages: 2409-2422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010

    • Author(s)
      Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
    • Journal Title

      Inflamm Bowel Dis. 16(4)

      Pages: 568-575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010

    • Author(s)
      Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
    • Journal Title

      Gastroenterology

      Volume: 139 Pages: 882-892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010

    • Author(s)
      Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
    • Journal Title

      J Immunol 184(5)

      Pages: 2671-2676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis.2010

    • Author(s)
      Kobayashi T, Naganuma M, Okamoto S, Hisamatsu T, Inoue N, Ichikawa H, Takayama T, Saito R, Sujino T, Ogata H, Iwao Y, Hibi T
    • Journal Title

      J Gastroenterol 45(11)

      Pages: 1129-37

    • NAID

      10027699761

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] アミノ酸と免疫2010

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      Functinal Food

      Volume: 第11号Vol.4 No.1 Pages: 16-22

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.2010

    • Author(s)
      Ojiro K, Ebinuma H, Nakamoto N, Wakabayashi K, Mikami Y, Ono Y, Po-Sung C, Usui S, Umeda R, Takaishi H, Yamagishi Y, Saito H, Kanai T, Hibi T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 399 Pages: 744-749

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] Imbalance of NKp44(+) NKp46(-) and NKp44(-) NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease2010

    • Author(s)
      Takayama T, Hisamatsu T, Kanai T, Hibi T., et al.
    • Journal Title

      Gastroenterology

      Volume: 139(3) Pages: 882-892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010

    • Author(s)
      Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T.
    • Journal Title

      J Immunol.

      Volume: 184 Pages: 2671-2676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] Competitio between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis2010

    • Author(s)
      Mikami Y, Kanai T, Hisamatsu T, Hibi T., et al.
    • Journal Title

      Eur J Immunol

      Volume: 40(9) Pages: 2409-2422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 血漿アミノ酸プロファイルを用いたIBDの診断IBD Research先端医学社2010

    • Author(s)
      久松理一、日比紀文
    • Volume
      12月号vol.4 no.4
    • Pages
      38-42
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Novel endoscopic activity index is useful for choosing treatment in severe active ulcerative colitis patients.2010

    • Author(s)
      Naganuma M, Ichikawa H, Inoue N, Kobayashi T, Okamoto S, Hisamatsu T, Kanai T, Ogata H, Iwao Y, Hibi T
    • Journal Title

      J Gastroenterol 45(9)

      Pages: 936-43

    • NAID

      10027698991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.2010

    • Author(s)
      Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
    • Journal Title

      Inflamm Bowel Dis.

      Volume: 16(4) Pages: 568-575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article]2010

    • Author(s)
      久松理一, 日比紀文
    • Journal Title

      炎症性腸疾患と腸管局所免疫 Annual Review 消化器 8-15(中外医学社)

      Pages: 8-15

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010

    • Author(s)
      Kamada N, Hisamatsu T, Kanai T, Hibi T., et al.
    • Journal Title

      Inflamm Bowel Dis

      Volume: 16(4) Pages: 568-575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010

    • Author(s)
      Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inone N, Ogata H, Hibi T.
    • Journal Title

      Eur J Immunol.

      Volume: Sep;40(9) Pages: 2409-2422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] 血漿アミノ酸プロファイルを用いたIBDの診断2010

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      IBD Research先端医学社

      Volume: 12月号vol.4 no.4 Pages: 38-42

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010

    • Author(s)
      Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T.
    • Journal Title

      Eur J Immunol.

      Volume: 40 Pages: 2409-2422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] 特集:生体防御と自然免疫-最近の知見Workshop実臨床のトピックスIBD発症進展における自然免疫の役割2010

    • Author(s)
      久松理一、日比紀文
    • Journal Title

      侵襲と免疫

      Volume: Vol.19 No.2 Pages: 39-42

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Imbalance of NKp44 (+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010

    • Author(s)
      Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
    • Journal Title

      Gastroenterology

      Volume: Sep;139(3) Pages: 882-892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment.2010

    • Author(s)
      Yaguchi T, Imaeda H, Kizaki M, Hosoe N, Suzuki H, Ogata H, Iwao Y, Kameyama K, Ikeda Y, Hibi T.
    • Journal Title

      Dig Endosc.

      Volume: 22 Pages: 316-318

    • NAID

      10028187355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010

    • Author(s)
      Takada Y, Hisamatsu T, Kanai T, Hibi T., et al.
    • Journal Title

      J Immunol

      Volume: 184(5) Pages: 2671-2676

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages2009

    • Author(s)
      Andou A, Hisamatsu T, Okamoto S, Chinen H, Kamada N, Kobayashi T, Hashimoto M, Okutsu T, Shimbo K, Takeda T, Matsumoto H, Sato A, Ohtsu H, Suzuki M, Hibi T.
    • Journal Title

      Gastroenterology 136(2)

      Pages: 564-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Retinoic acid contributes to the induction of IL-12-hypoproducing dendritic cells2009

    • Author(s)
      Wada Y, Hisamatsu T, Kamada N, Okamoto S, Hibi T.
    • Journal Title

      Inflamm Bowel Dis. 15(10)

      Pages: 1548-1556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article]2009

    • Author(s)
      齊藤理子, 久松理一, 日比紀文
    • Journal Title

      マクロファージからのIL-23産生と大腸炎、共生菌の関与臨床免疫・アレルギー科52巻4号(科学評論社)

      Pages: 384-388

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article]2009

    • Author(s)
      久松理一, 日比紀文
    • Journal Title

      腸管マクロファージとIBD IBD Research vol.3 no.3(先端医学者)

      Pages: 183-187

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article]2009

    • Author(s)
      久松理一, 日比紀文
    • Journal Title

      ATG16L1とTNFSF15G.I Research vol.17 no.6(先端医学社)

      Pages: 548-550

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability2009

    • Author(s)
      Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
    • Journal Title

      J Immunol. 183(3)

      Pages: 1724-1731

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article]2009

    • Author(s)
      久松理一, 日比紀文
    • Journal Title

      Th-17細胞の機能はどこまで明らかになれたか?IBD Research vol.2 no.4(先端医学社)

      Pages: 308-313

    • Data Source
      KAKENHI-PROJECT-21249048
  • [Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells.2008

    • Author(s)
      Kamada N, Maeda K, Inoue N, Hisamatsu T, Okamoto S, Hong KS, Yamada T, Watanabe N, Tsuchimoto K, Ogata H, Hibi T
    • Journal Title

      Infect Immun 76(1)

      Pages: 214-220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease2008

    • Author(s)
      Takaishi H, Inoue N, Hibi T, et. al.
    • Journal Title

      Int J Med Microbiol (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Endoscopic and chromoendoscopic atlas featuring dysplastic lesions in surveillance colonoscopy for patients with long-standing ulcerative colitis.2008

    • Author(s)
      Matsumoto T, Iwao Y, Igarashi M, Watanabe K, Otsuka K, Watanabe T, Iizuka B, Hida N, Sada M, Chiba T, Kudo SE, Oshitani N, Nagawa H, Ajioka Y, Hibi T
    • Journal Title

      Inflamm Bowel Dis 14(2)

      Pages: 259-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008

    • Author(s)
      Kamada, N, Inoue, N, Hibi, T, et. al.
    • Journal Title

      Infect Immun 76(1)

      Pages: 214-220

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.2008

    • Author(s)
      Komiyama T, Yajima T, Kubota R, Iwao Y, Sakuraba A, Funakoshi S, Negishi K, Minami I, Tanaka Y, Mae H, Hibi T
    • Journal Title

      J Crohns Colitis 2(4)

      Pages: 315-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transd uction in intestinal epithelial cells2008

    • Author(s)
      Kamada N, Inoue N, Hibi T, et. al.
    • Journal Title

      Infect Immun 76

      Pages: 214-220

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.2008

    • Author(s)
      Takaishi H, Matsuki T, Nakazawa A, Takada T, Kado S, Asahara T, Kamada N, Sakuraba A, Yajima T, Higuchi H, Inoue N, Ogata H, Iwao Y, Nomoto K, Tanaka R, Hibi T
    • Journal Title

      Int J Med Microbiol 298(5-6)

      Pages: 463-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Journal Article] Imbalance in intesthlal microf[ora constitution could be ivolved in thepathogenesis of inflammatory bowel disease2008

    • Author(s)
      Takaishi H, Inoue N, Hibi, T, et. al.
    • Journal Title

      Int J Med Microbiol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Nonpathogenic Escherichia coh strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008

    • Author(s)
      Kamada N, Inoue N, Hibi T, et. al.
    • Journal Title

      Infect Immun 76

      Pages: 214-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice2008

    • Author(s)
      Nanno M, Inoue N, Hibi T, et. al.
    • Journal Title

      Gastroenterology 134

      Pages: 481-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.2008

    • Author(s)
      Nanno M, Kanari Y, Naito T, Inoue N, Hisamatsu T, Chinen H, Sugimoto K, Shimomura Y, Yamagishi H, Shiohara T, Ueha S, Matsushima K, Suematsu M, Mizoguchi A, Hibi T, Bhan AK, Ishikawa
    • Journal Title

      Gastroenterology 134(2)

      Pages: 481-490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Journal Article] Exclusive increase of CX3CR1+CD28-CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.2007

    • Author(s)
      Kobayashi T, Nakazawa A, Hibi T et al.
    • Journal Title

      Inflamm Bowel Disease (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007

    • Author(s)
      Matsuoka K, Hibi T et al.
    • Journal Title

      Am J Gastroenterol (in press)

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007

    • Author(s)
      Yoshizawa S, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine2007

    • Author(s)
      Matsumoto T, Hibi T, Watanabe M et al.
    • Journal Title

      Gastroenterology 128・7

      Pages: 1851-1867

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis2007

    • Author(s)
      Yoshizawa S, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells-their developmental and behavioral characteristics.2007

    • Author(s)
      Ishikawa H, Hibi T et al.
    • Journal Title

      Immunol Rev 215・1

      Pages: 154-165

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007

    • Author(s)
      Ishikawa H, Hibi T et al.
    • Journal Title

      Immunol Rev 215・1

      Pages: 154-165

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007

    • Author(s)
      Isliikawa H, Naito T, Iwanaga T, Takahashrlwanaga H, Suematsu M, Hibi T, Nanno M
    • Journal Title

      Immunol Rev 215 (1)

      Pages: 154-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007

    • Author(s)
      Ishikawa H, Hibi T et al.
    • Journal Title

      Immunol Rev 215・1

      Pages: 154-165

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Clinical significance of serum. p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007

    • Author(s)
      Yoshizawa S, Matsuoka K, Inoue N, Takaishi H, Ogata H, Iwao Y, Mukai M, Fujita T, Kawakami Y, Hibi H.
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007

    • Author(s)
      Yoshizawa S, Inoue N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Exclusive increase of CX3CR1^+CD28^-CD4^+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.2007

    • Author(s)
      Kobayashi T, Okamoto S, Iwakami Y, Nakazawa A, Hisamatsu T, Chinen H, Kamada N, Imai T, Goto H, Hibi T.
    • Journal Title

      Inflamm Bowel Dis. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007

    • Author(s)
      Ishikawa H, Hibi T et al.
    • Journal Title

      Immunol. Rev 215・1

      Pages: 154-165

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients.2007

    • Author(s)
      Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajitna T, Hisamatsu T, Okamoto S, Morohoshi Y, Izumiya M, Ichikawa H, Sato T, Inoue N, Ogata H, Hibi T.
    • Journal Title

      Am J Gastroenterol 102 (2)

      Pages: 331-337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007

    • Author(s)
      Matsuoka K, Iwao Y, Inoue N, Hibi T et al.
    • Journal Title

      Am J Gastroenterol (in press)

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007

    • Author(s)
      Matsuoka K, Inoue N, Hibi T et al.
    • Journal Title

      Am J Gastroenterol (in press)

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007

    • Author(s)
      Yoshizawa S, Inoue N, Iwao Y, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Inoue N, Hibi T et al.
    • Journal Title

      J Gastroenterol 41・4

      Pages: 318-324

    • NAID

      10018141558

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.2006

    • Author(s)
      Ogata H, Hibi T et al.
    • Journal Title

      Gut 55(9)

      Pages: 1255-1262

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2006

    • Author(s)
      Matsuoka K, Hibi T et al.
    • Journal Title

      Am J Gastroenterol 102(2)

      Pages: 331-337

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Hibi T et al.
    • Journal Title

      J Gastroenterol 41(4)

      Pages: 318-324

    • NAID

      10018141558

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Matsuoka K, Chinen H, Kamada N, Sato T, Hisamatsu T, Okamoto S, Inoue N, Takaishi H, Ogata H, Iwao Y, Hibi T
    • Journal Title

      J Gastroenterol 41 (4)

      Pages: 318-324

    • NAID

      10018141558

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Inoue N, Iwao Y, Hibi T et al.
    • Journal Title

      J Gastroenterol Apr.41(4)

      Pages: 318-324

    • NAID

      10018141558

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Hibi T et al.
    • Journal Title

      J Gastroenterol 41・4

      Pages: 318-324

    • NAID

      10018141558

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006

    • Author(s)
      Morohoshi Y, Matsuoka K, Chinen H, Kamada N, Sato T, Hisamatsu T, Okamoto S, Inoue N, Takaishi H, Ogata H, Iwao Y, Hibi T
    • Journal Title

      J Gastroenterol 41(4)

      Pages: 318-24

    • NAID

      10018141558

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Nonpathogenic Escherichia coil strain Nissle1917 prevents murine acute and chronic colitis2006

    • Author(s)
      Kamada N, Inoue N, Hibi T, et. al.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Cytomegalovirus is frequently reactivated and disappears without anti-viral agents in ulcerative colitis patients.2006

    • Author(s)
      Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajima T, Hisamatsu T, Okamoto S, Morohoshi Y, Izumiya M, Ichikawa H, Sato T, Inoue N, Ogata H, Hibi T
    • Journal Title

      Am J Gastroenterol 102(2)

      Pages: 331-337

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis2006

    • Author(s)
      Morohoshi Y, Hibi T et al.
    • Journal Title

      J Gastroenterol 41・4

      Pages: 318-324

    • NAID

      10018141558

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.2006

    • Author(s)
      Ogata H, Matsui T, Nakamura M, Iida M, Takazoe M, Suzuki Y, Hibi T
    • Journal Title

      Gut 55(9)

      Pages: 1255-1262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Nonpathogenic Escherichia coli strain Nisslel917 prevents murine acute and chronic colitis.2006

    • Author(s)
      Kamada N, Inoue N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] The logics of leucocytapheresis as a natural biological therapy for inflammatory bowel disease.2006

    • Author(s)
      Kanai T, Hibi T, Watanabe M
    • Journal Title

      Expert Opin Biol Ther. 6

      Pages: 453-466

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390215
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis2006

    • Author(s)
      Kamada, N, Inoue, N, Hibi, T, et. al.
    • Journal Title

      Inflamm Bowel Dis 11(5)

      Pages: 455-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Styrene-Coated Iron Nanobeads for Medical Use2005

    • Author(s)
      Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M.
    • Journal Title

      IEEE Trans.Magn.Soc. 41,10

      Pages: 4143-4145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005

    • Author(s)
      Sato I, Hibi T, et al.
    • Journal Title

      GUT (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Thi immune response.2005

    • Author(s)
      Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T
    • Journal Title

      GUT (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005

    • Author(s)
      Tahara T, Hibi T et al.
    • Journal Title

      J Gastroenterol Hepatol 20・5

      Pages: 710-715

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005

    • Author(s)
      Tahara T, Inoue N, Hisamatsu T, Kashiwagi K, Takaishi H, Kanai T, Watanabe M, Ishii H, Hibi T.
    • Journal Title

      J Gastrornt Hepatol 20

      Pages: 710-715

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis.2005

    • Author(s)
      Kamada N, Jnoue N, Hisamatsu T, Okamoto S, Matsuoka K, Sato T, Chinen H, Hong KS, Yamada T, Suzuki Y, Suzuki T, Watanabe N, Tsuchimoto K, Hibi T
    • Journal Title

      Inflamm Bowel Dis (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] Abnormally Differentiated Subsets of Intestinal Macrophage Play a Key Role in Th1-Dominant Chronic Colitis through Excess Production of IL-12 and IL-23 in Response to Bacteria.2005

    • Author(s)
      Kamada, N., Hisamatsu, T., Okamoto, S., Sato, T., Matsuoka, K., Arai, K., Nakai, T., Hasegawa, A., Inoue, N., Watanabe, N., Akagawa, K., Hibi, T.
    • Journal Title

      J of Immunol 175・10

      Pages: 6900-6908

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005

    • Author(s)
      Hibi T, Sakuraba A
    • Journal Title

      Nat Clin Pract Gastroenterol & Hepatol 2・5

      Pages: 200-202

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis 11(5)

      Pages: 455-463

    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Thl-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N., Hisamatsu T., Okamoto S., Sato T., Matsuoka K., Arai K., Nakai T., Hasegawa A., Inoue N., Watanabe N., Akagawa KS., Hibi T.
    • Journal Title

      J Immunol 175

      Pages: 6900-6908

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005

    • Author(s)
      Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T
    • Journal Title

      Gut 54

      Pages: 1254-1262

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N, Hisamatsu T, Okamoto S, Sato T, Matsuoka K, Arai K, Nakai T, Hasegawa A, Inoue N, Watanabe N, Akagawa KS, Hibi T
    • Journal Title

      J.Immunol 175

      Pages: 6900-6908

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005

    • Author(s)
      Hitotsumatsu O, Hibi T et al.
    • Journal Title

      J Gastroenterol 40・10

      Pages: 956-963

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      J Immunol 175・10

      Pages: 6900-6908

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005

    • Author(s)
      Tahara, T., Inoue, N., Hisamatsu, T., Kashiwagi, K., Takaishi, H., Kanai, T., Watanabe, M., Ishii, H., Hibi, T.
    • Journal Title

      J Gastroenterol Hepatol 20・5

      Pages: 710-715

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Styrene-Coated Iron Nanobeads for Medical Use.2005

    • Author(s)
      Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M
    • Journal Title

      IEEE Trans.Magn.Soc. 41

      Pages: 4143-4145

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Data Source
      KAKENHI-PROJECT-17659221
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005

    • Author(s)
      Sato T, Nakai T, Tamura N, Okamoto S., Matsuoka K, Sakuraba A., Fukushima T, Uede T., Hibi T
    • Journal Title

      Gut 54

      Pages: 1254-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Hibi T, Watanabe M et al.
    • Journal Title

      Gastroenterology 128・7

      Pages: 1851-1867

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Preparlation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening2005

    • Author(s)
      Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
    • Journal Title

      JOURNAL OF APPLIED PHYSICS 97

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and hronic colitis.2005

    • Author(s)
      da, N., Inoue, N., Hisamatsu, T., oto, S., Matsuoka, K., Sato, T., en, H., Su Hong K., Yamada, T., ki, Y., Suzuki, T., Watanabe, N., himoto, K., Hibi, T.
    • Journal Title

      Inflamm Bowel Dis 11・5

      Pages: 455-463

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Preparation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening.2005

    • Author(s)
      Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
    • Journal Title

      JOURNAL OF APPLIED PHYSICS 97

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005

    • Author(s)
      Hitotsumatsu O, Inoue N, Hibi T, Ishikawa H et al.
    • Journal Title

      J Gastroenterol 40・10

      Pages: 956-963

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Preparlation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening2005

    • Author(s)
      Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
    • Journal Title

      JOURNAL OF APPLIED PHYSICS 97,10Q919

      Pages: 1-3

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7R^<high>CD4^+ mucosal T cells in mice.2005

    • Author(s)
      Okada E, Yamazaki M, Tanabe M, Takeuchi T, Nanno M, Oshima S, Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Hibi T, Watanabe M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 288

      Pages: 745-754

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Leudocytapheresis in ulcerative colitis : results of a multicenter double-blind prospective case-control study pith sham apheresis as placebo treatment.2005

    • Author(s)
      Sawada, k., Kusugami, K., Suzuki, Y., Bamba, T., Munakata, A., Hibi, T., Shimoyama, T.
    • Journal Title

      Am J Gastroenterol 100・6

      Pages: 1362-1369

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Okamoto R, Yajima T, Mon T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
    • Journal Title

      Gastroenterology 128(7)

      Pages: 1851-67

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590674
  • [Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005

    • Author(s)
      Hitotsumatsu O, Hibi T et al.
    • Journal Title

      J Gastroenterol 40・10

      Pages: 956-963

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005

    • Author(s)
      Hibi, T., Sakuraba, A
    • Journal Title

      Nat Clin Pract Gastroenterol & Hepatol 2・5

      Pages: 200-202

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005

    • Author(s)
      Hitotsumatsu, O., Hamada, H., Naganuma, M., Inoue, N., Ishii, H., Hibi, T., Ishikawa, H.
    • Journal Title

      J Gastroenterol 40・10

      Pages: 956-963

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis.2005

    • Author(s)
      Kamada N, Inoue N, Hisamatsu T, Okamoto S, Matsuoka K, Sato T, Chinen H, Su Hong K, Yamada T, Suzuki Y, Suzuki T, Watanabe N, Tsuchimoto K, Hibi T.
    • Journal Title

      Inflamm Bowel Dis 11 (5)

      Pages: 455-463

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      J Immunol 175(10)

      Pages: 6900-6908

    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005

    • Author(s)
      Sato T, Hibi T et al.
    • Journal Title

      Gut 54(9)

      Pages: 1254-1262

    • Data Source
      KAKENHI-PROJECT-17590676
  • [Journal Article] Styrene-Coated Iron Nanobeads for Medical Use2005

    • Author(s)
      Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M.
    • Journal Title

      IEEE Trans. Magn. Soc. 41, 10

      Pages: 4143-4145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N, Hibi T et al.
    • Journal Title

      J Immunol 175・10

      Pages: 6900-6908

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Therapeutic efficacy of infliximab on active Crohn's disease under nutritional therapy.2005

    • Author(s)
      Matsumoto, T., Iida, M., Kohgo, Y., Imamura, A, Kusugami, K., Nakano, H., Fujiyama, Y., Matsui, T., Hibi, T.
    • Journal Title

      Scand J Gastroenterol 40・12

      Pages: 1423-1430

    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005

    • Author(s)
      Hibi T, Sakuraba A
    • Journal Title

      Nat Clin Pract Gastroenterol & Hepatol 2・5

      Pages: 200-202

    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005

    • Author(s)
      Kamada N, Inoue N, Hibi T et al.
    • Journal Title

      J Immunol 175・10

      Pages: 6900-6908

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005

    • Author(s)
      Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
    • Journal Title

      Gastroenterology 127 (7)

      Pages: 1851-1867

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209024
  • [Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005

    • Author(s)
      Sato T, Hibi T, et al.
    • Journal Title

      GUT (in press)

    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005

    • Author(s)
      Tahara T, Inoue N, Hibi T et al.
    • Journal Title

      J Gastroenterol Hepatol 20・5

      Pages: 710-715

    • Data Source
      KAKENHI-PROJECT-17590677
  • [Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004

    • Author(s)
      Okazawa A, Kanai T, Nakamaru K, Sato T, Inoue N, Ogata H, Jwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto R, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T
    • Journal Title

      Clin Exp Immunol 136(2)

      Pages: 269-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Human intestinal epithelia-derived IL-18 is a potent prolifrerative factor for intraepithelial lymphocytes synergistically with IL-2, IL-7 and IL-15.2004

    • Author(s)
      Okazawa A, Kanai T, Nakamaru T, Sato T, Inoue N, Ogata H, Iwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto R, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T.
    • Journal Title

      Clin Exp Immunol 136

      Pages: 269-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammtory bowel disease.2004

    • Author(s)
      Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
    • Journal Title

      Gastroenterology 126

      Pages: 829-839

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004

    • Author(s)
      Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T
    • Journal Title

      Cancer Res. 64(22)

      Pages: 8239-8248

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Croha's disease.2004

    • Author(s)
      Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
    • Journal Title

      Gut 53(9)

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004

    • Author(s)
      Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Atsushi Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.
    • Journal Title

      Gut 53

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.2004

    • Author(s)
      Maeda N, Watanabe M, Okamoto S, Kanai T, Yamada T, Hata J, Hozumi N, Katsume A, Nuriya H, Sandhu J, Ishii H, Kohara M, Hibi T.
    • Journal Title

      Liver Int 24

      Pages: 259-267

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004

    • Author(s)
      Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
    • Journal Title

      Gut 53(9)

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004

    • Author(s)
      Matsuoka K, Hibi T, et al.
    • Journal Title

      GUT 53・9

      Pages: 1303-1308

    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004

    • Author(s)
      Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
    • Journal Title

      Gut 53

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Hyperexpression of inducible costimulator its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Hibi T, et al.
    • Journal Title

      Gastroenterology 126・3

      Pages: 829-839

    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T.
    • Journal Title

      Gastroenterology 126

      Pages: 829-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
    • Journal Title

      Gastroenterology 126

      Pages: 829-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto 5, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kxoczek RA, Fukushima T, Ishii H, Hibi T
    • Journal Title

      Gastroenterology 126(3)

      Pages: 829-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004

    • Author(s)
      Okazawa A, Hibi T, et al.
    • Journal Title

      Cin Exp Immunol 136・2

      Pages: 269-276

    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
    • Journal Title

      Gastroenterology 126(3)

      Pages: 829-839

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004

    • Author(s)
      Matsuoka K, Hibi T, et al.
    • Journal Title

      GUT 53

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004

    • Author(s)
      Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T
    • Journal Title

      Cancer Res 64(22)

      Pages: 8239-8248

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004

    • Author(s)
      Sato T, Hibi T, et al.
    • Journal Title

      Gastroenterology 126

      Pages: 829-839

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Human intestinal epithelial cell-derived interleukin (IL)-18, along with IL-2, IL-7 and IL-15, a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004

    • Author(s)
      Okazawa A, Hibi T, et al.
    • Journal Title

      Clin Exp Immunol 136

      Pages: 269-276

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2004

    • Author(s)
      Ezaki T, Watanabe M, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
    • Journal Title

      Cancer Res. 63

      Pages: 3747-3749

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal canders.2004

    • Author(s)
      Ezaki T, Watanabe M, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
    • Journal Title

      Cancer Res 63

      Pages: 3747-3749

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease2004

    • Author(s)
      Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
    • Journal Title

      Gut 53

      Pages: 1303-1308

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15209019
  • [Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004

    • Author(s)
      Okazawa A, Kanai T, Nakamaru K, Sato T, Jnoue N, Ogata H, Iwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto H, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T
    • Journal Title

      Clin Exp Immunol 136(2)

      Pages: 269-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] Granulocytapheresis is useful as an alterative therapy in patients with steroid-refractory or -dependent ulcerative colitis.2004

    • Author(s)
      Naganuma M, Funakoshi S, Sakuraba A, Takagi H, Inoue N, Ogata H, Iwao Y, Ishii H, Hibi T
    • Journal Title

      Inflamm Bowel Dis 10(3)

      Pages: 251-257

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis.2003

    • Author(s)
      Yamazaki M, Yajima T, Tanabe M, Fukui K, Okada E, Okamoto R, Oshima S, Nakamura T, Kanai T, Takeuchi T, Uehira M, Ishikawa H, Hibi T, Watanabe M.
    • Journal Title

      J Immunol 171

      Pages: 1556-1563

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate (DSS) colitis in mice.2003

    • Author(s)
      Takagi H, Kanai T, Okazawa A, Kishi Y, Sato T, Takaishi H, Inoue N, Ogata H, Iwao Y, Hoshino K, Takeda K, Akira S, Ishii H, Watanabe M, Hibi T.
    • Journal Title

      Scan J Gastroenterol 33

      Pages: 837-844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice.2003

    • Author(s)
      Takagi H, Hibi T, et al.
    • Journal Title

      Scand J Gastroenterol 38

      Pages: 837-844

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003

    • Author(s)
      Ezaki, Watanabe M, Inoue N, Kanai T^#, Ogata H, Iwao Y, Ishii H, Hibi T.
    • Journal Title

      Cancer Res 63

      Pages: 3747-3749

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Contrasting action of IL-12 and IL-15 in the development of dextran sodium sulfate colitis in mice.2003

    • Author(s)
      Takagi T, Kanai T, Okazawa A, Sato T, Takaishi H, Inoue N, Ogata H, Hoshino K, Takeda K, Akira S, Watanabe M, Jshii H, Hibi T
    • Journal Title

      Scand J Gastroenterol 38(8)

      Pages: 837-844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590685
  • [Journal Article] Ameliorating effect of anti-ICOS monoclonal antibody in a murine model of chronic colitis.2003

    • Author(s)
      Totsuka T, Kanai T^#, Iiyama R, Uraushihara K, Yamazaki M, Okamoto R, Hibi T, Tezuka K, Azuma M, Akiba H, Yagita H, Okumura K, Watanabe M.
    • Journal Title

      Gastroenterology 124

      Pages: 410-421

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] IL-18 overexpression exacerbates the development of colitis with marked infiltrates macrophages in IL-18 transgenic mice.2003

    • Author(s)
      Ishikura T, Kanai T^#, Uraushihara K, Iiyama R, Makita S, Totsuka T, Yamazaki M, Sawada T, Nakamura T, Kitahora T, Hibi T, Hoshino T, Watanabe M.
    • Journal Title

      J Gastroenterol Hepatol 18

      Pages: 960-969

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Hyperexpression of inducible costimulator (ICOS) on lamina propria mononuclear cells in rat dextran sulfate sodium (DSS).2003

    • Author(s)
      Ishii K, Kanai T, Ishikura T, Totsuka T, Uraushihara K, Yamazaki M, Okamoto R, Araki A, Ohka S, Miyata T, Nakamura T, Kitahora T, Hibi T, Tezuka K, Watanabe M.
    • Journal Title

      J Gastroenterol Hepatol 19

      Pages: 174-181

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003

    • Author(s)
      Ezaki T, Watanabe M, Inoue N, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
    • Journal Title

      Cancer Res 63(13)

      Pages: 3747-3749

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate colitis in mice.2003

    • Author(s)
      Takagi T, Kanai T, Okazawa A, Sato T, Takaishi H, Inoue N, Ogata H, Hoshino K, Takeda K, Akira S, Watanabe M, Ishii H, Hibi T
    • Journal Title

      Scand J Gastroenterol 38(8)

      Pages: 837-844

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590684
  • [Journal Article] Damaged epithella regenerated by bone marrow-derived cells in the human gastrointestinal tract.2002

    • Author(s)
      Okamoto, R., Yajima, T., Yamazalci, M., Kanai, T., Mukai, M., Okamoto, S., Ikeda, Y., Hibi, T., Inazawa, J., Watanabe, M.
    • Journal Title

      Nature Medicine 8

      Pages: 1011-1017

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13GS0015
  • [Journal Article] TGR5 signaling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease

    • Author(s)
      Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, KoganeiK, Sugita A, Kanai T, Hibi T
    • Journal Title

      Immunology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Activated Hepatic Stellate Cells Mediate the Differentiation of Macrophages.

    • Author(s)
      Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, and Hibi T
    • Journal Title

      Hepatology Research

      Volume: (in press)

    • NAID

      10031194568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells

    • Author(s)
      Nishida A, Nagahama K, Imaeda H, Ogawa A, Lau CW, Kobayashi T, Hisamatsu T, Preffer FI, Mizoguchi E, Ikeuchi H, Hibi T, Fukuda M, Andoh A, Blumberg RS, Mizoguchi A
    • Journal Title

      J Exp Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.

    • Author(s)
      Matsumoto T, Okamoto R, Yagima T, Mori T, Okamoto S, Ikeda Y, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
    • Journal Title

      Gastroenterology (in the press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590627
  • [Journal Article] Anticoagulation therapy dramatically improved severe sigmoiditis with findings resembling inflammatory bowel disease, which was caused by mesenteric venous thrombosis

    • Author(s)
      Mikami Y, Kanai T, Iwasaki E, Naganuma M, Yamagishi Y, Shimoda M, Matsuoka K, Hisamatsu T, Iwao Y, Ogata H, Nakatsuka S, Mukai M, Hibi T
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Presentation] 教育講演「難病克服に向けた新しい消化管再生医療」2015

    • Author(s)
      日比紀文
    • Organizer
      第11回日本消化管学会総会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 潰瘍性大腸炎患者に対する大腸カプセル内視鏡前処置の工夫(クエン酸モサプリドの効果)2015

    • Author(s)
      細江直樹、宮永亮一、三枝慶一郎、小林拓、中野雅、長沼誠、日比紀文、金井隆典、緒方晴彦
    • Organizer
      第8回日本カプセル内視鏡学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-15
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 当院における炎症性腸疾患に対するチオプリン製剤使用の実態2015

    • Author(s)
      梅田智子、小林拓、中野雅、常松令、芹澤宏、渡辺憲明、日比紀文
    • Organizer
      第11回日本消化管学会総会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-14
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 潰瘍性大腸炎粘膜治癒評価における便中S100A12の有用性2015

    • Author(s)
      小林拓、中野雅、梅田智子、芹澤宏、渡辺憲明、黒沼智、竹内修、日比紀文
    • Organizer
      第11回日本消化管学会総会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 大腸カプセル内視鏡使用経験に関する国内アンケート調査の結果報告-日本カプセル内視鏡学会保健委員会より2015

    • Author(s)
      樋口和秀、日比紀文、藤山佳秀、松井敏幸、伊藤文生
    • Organizer
      第8回日本カプセル内視鏡学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2015-02-15
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 広汎な小腸病変を来した潰瘍性大腸炎の一例2014

    • Author(s)
      森川淳、小林拓、筋野智久、中野雅、加藤裕佳子、梅田智子、芹澤宏、日比紀文
    • Organizer
      日本消化器病学会 関東支部第331回例会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-20
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 難治性潰瘍性大腸炎治療におけるタクロリムスの位置づけと適正使用法2014

    • Author(s)
      日比紀文
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-23
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 潰瘍性大腸炎患者に対するクエン酸モサプリドを用いた大腸カプセル内視鏡前処置法2014

    • Author(s)
      細江直樹、中野雅、南木康作、三枝慶一郎、碓井真吾、筋野智久、小林拓、松岡克善、長沼誠、久松理一、井上詠、芹澤宏、日比紀文、金井隆典、緒方晴彦
    • Organizer
      第32回 日本大腸検査学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-06
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 本邦から発信する最適なUC治療戦略2014

    • Author(s)
      日比紀文
    • Organizer
      第1回 Biologics Workshop on IBD
    • Place of Presentation
      東京
    • Year and Date
      2014-04-26
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 法制化される新たな難病対策における専門医の役割について2014

    • Author(s)
      日比紀文
    • Organizer
      第100回日本消化器病学会総会
    • Place of Presentation
      東京
    • Year and Date
      2014-04-24
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] HUMIRAによる患者参加型治療の実践:生物学的製剤投与法選択のポイント2014

    • Author(s)
      日比紀文
    • Organizer
      HUMIRA IBD Forum
    • Place of Presentation
      東京
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Current and future treatments of IBD in Japan.Are they different from Westerns?2014

    • Author(s)
      Toshifumi Hibi
    • Organizer
      2014 PUMCH International Digestive Disease Forum
    • Place of Presentation
      北京(中国)
    • Year and Date
      2014-04-19
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患に対する抗体療法2013

    • Author(s)
      日比紀文
    • Organizer
      第107回日本内科学会総会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] The future perspective and issues of IBD in Asia2013

    • Author(s)
      Toshifumi hibi
    • Organizer
      1th AOCC
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患の専門医を目指す若手医師へのメッセージ2013

    • Author(s)
      日比紀文
    • Organizer
      第11回IBDセミナー
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Collaboration between the East Asia IBD Society and ECCO2012

    • Author(s)
      Toshifumi Hibi
    • Organizer
      ECCO Meeting
    • Place of Presentation
      Barcelona Spain(招待講演)
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Early normalization of C-reactive protein (CRP)by infliximab is a predictive factor of sustained longterm clinical efficacy in crohn's disease.2012

    • Author(s)
      Kimura K, Matsuoka K, Kanai T, Okamoto S,Hisamatsu T, Inoue N, Yajima T, Ogata H, I wa o Y, Hibi T
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research
    • Place of Presentation
      Tokyo
    • Year and Date
      2012-07-14
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Presentation] Collaboration between the East Asia IBD Society and ECCO2012

    • Author(s)
      Toshifumi Hibi
    • Organizer
      ECCO Meeting
    • Place of Presentation
      Spain
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Role of Endoscopy in daily clinical practice : example from Japan2012

    • Author(s)
      Toshifumi Hibi
    • Organizer
      Leading Change in IBD Meeting
    • Place of Presentation
      Prague
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Role of Endoscopy in daily clinical practice : example from Japan2012

    • Author(s)
      Toshifumi Hibi
    • Organizer
      Leading Change in IBD Meeting
    • Place of Presentation
      Prague Ceska Republika(招待講演)
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Early normalization of C-reactive protein (CRP)by infliximab is a predictive factor of sustained long-term clinical efficacy in crohn’s disease.2012

    • Author(s)
      26. Kimura K, Matsuoka K, Kanai T, Okamoto S, Hisamatsu T, Inoue N, Yajima T, Ogata H, Iwao Y, Hibi T
    • Organizer
      The 14th Meeting of International Conference on Ulcer Research.
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-24659374
  • [Presentation] How to avoid malpractice and deal with difficult IBD cases2011

    • Author(s)
      Toshifumi Hibi
    • Organizer
      IBD Update II
    • Place of Presentation
      台北台湾(招待講演)
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] How to avoid malpractice and deal with difficult IBD cases2011

    • Author(s)
      Toshifumi Hibi
    • Organizer
      IBD Update
    • Place of Presentation
      台湾
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 潰瘍性大腸炎治療の新展開2010

    • Author(s)
      日比紀文
    • Organizer
      第89回日本消化器内視鏡学会九州支部例会支部例会ランチョンセミナー
    • Place of Presentation
      九州
    • Year and Date
      2010-06-19
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Japanese Patients With Moderately to Severely Active Crohn's Disease Experience Improved Quality of Life With Adalimumab Treatment2010

    • Author(s)
      日比紀文
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans
    • Year and Date
      2010-05-03
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] 炎症性腸疾患をアミノ酸代謝から考える2010

    • Author(s)
      久松理一、日比紀文
    • Organizer
      第8回日本機能性食品医用学会総会シンポジウムI免疫と機能性食品
    • Place of Presentation
      大津ピアザ淡海
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] クローン病の病態解明と治療開発2010

    • Author(s)
      日比紀文
    • Organizer
      第6回日本消化管学会総会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2010-02-20
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 血漿アミノ酸プロファイルを用いた炎症性腸疾患の診断・活動性モニタリング2010

    • Author(s)
      久松理一、井上詠、松岡克善、斉藤理子、筋野智久、米野和明、三好潤、三上洋平、岩男泰、緒方晴彦、金井隆典、日比紀文、安藤朗、藤山佳秀、内山和彦、高木智久、内藤裕二、吉川敏一
    • Organizer
      難治性腸管障害調査研究班
    • Place of Presentation
      東京
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] 大腸腫瘍性病変に対するESDの工夫2010

    • Author(s)
      今枝博之、細江直樹、中溝裕雅、別所理恵子、齋藤理子、小池祐司、井上詠、石井良幸、長谷川博俊、岩男泰、緒方晴彦、北川雄光、日比紀文
    • Organizer
      第79回日本消化器内視鏡学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-15
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Presentation] Current Therapy of IBD-Current Concepts2010

    • Author(s)
      日比紀文
    • Organizer
      IBD Symposium in Taipei
    • Place of Presentation
      台湾
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 炎症性腸疾患に対する抗体療法2010

    • Author(s)
      日比紀文
    • Organizer
      第107回日本内科学会講演会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-11
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010

    • Author(s)
      久松理一、鎌田信彦、高山哲朗、齋藤理子、米野和明、松岡克善、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
    • Organizer
      第47回日本消化器免疫学会総会、シンポジウム
    • Place of Presentation
      滋賀
    • Year and Date
      2010-07-09
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] 潰瘍性大腸炎治療の新展開2010

    • Author(s)
      日比紀文
    • Organizer
      第89回日本消化器内視鏡学会九州支部例会支部例会ランチョンセミナー
    • Place of Presentation
      福岡
    • Year and Date
      2010-06-19
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] Japanese Patients With Moderately to Severely Active Crohn'sDisease Experience Improved Quality of Life With Adalimumab Treatment2010

    • Author(s)
      日比紀文
    • Organizer
      Digestive Disease Week 2010
    • Place of Presentation
      New Orleans
    • Year and Date
      2010-05-03
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 血漿アミノ酸プロファイルを用いた炎症性腸疾患の診断・活動性モニタリング2010

    • Author(s)
      久松理一、井上詠、松岡克善、斉藤理子、筋野智久、米野和明、三好潤、三上洋平、岩男泰、緒方晴彦、金井隆典、日比紀文、安藤朗、藤山佳秀、内山和彦、高木智久、内藤裕二、吉川敏一
    • Organizer
      難治性腸管障害調査研究班
    • Place of Presentation
      東京
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Immunomodulation therapy for IBD2010

    • Author(s)
      日比紀文
    • Organizer
      2010 Immune-Mediated Digestive Diseases Forum in China
    • Place of Presentation
      北京
    • Year and Date
      2010-06-13
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] 炎症性腸疾患をアミノ酸代謝から考える2010

    • Author(s)
      久松理一、日比紀文
    • Organizer
      第8回日本機能性食品医用学会総会シンポジウムI免疫と機能性食品
    • Place of Presentation
      大津ピアザ淡海
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Current Therapy of IBD-Current Concepts2010

    • Author(s)
      日比紀文
    • Organizer
      IBD Symposium in Taipei
    • Place of Presentation
      台湾
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-22659151
  • [Presentation] 日比紀文Current Therapy of IBDCurrent Concepts2010

    • Author(s)
      日比紀文
    • Organizer
      IBD Symposium
    • Place of Presentation
      Taipei台湾
    • Year and Date
      2010-08-21
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] Immunomodulation therapy for IBD2010

    • Author(s)
      日比紀文
    • Organizer
      2010 Immune-Mediated Digestive Diseases Forum in China
    • Place of Presentation
      北京
    • Year and Date
      2010-06-13
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 炎症性腸疾患に対する抗体療法2010

    • Author(s)
      日比紀文
    • Organizer
      第107回日本内科学会講演会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-11
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 胆汁酸はTGR5受容体を介してIL-12低産生型樹状細胞に分化誘導する/Bile acids generate IL-12 hypoproducingDCs via Tgr5 signaling pathway2009

    • Author(s)
      Saito R, Hisamatsu T, Takayama T, Kamada N, Ando S, Inoue N, Okamoto S, Kanai T, Hibi T
    • Organizer
      第39回日本免疫学会総会・学術集会、ワークショップ
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-02
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] 炎症性腸疾患診療の新時代2009

    • Author(s)
      日比紀文
    • Organizer
      第64回日本大腸肛門病学会学術集会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] 早期大腸癌の内視鏡摘除後における大腸内視鏡サーベイランスの検討2009

    • Author(s)
      井田陽介、今枝博之、細江直樹、中溝裕雅、別所理恵子、斉藤理子、小池祐司、井上詠、長谷川博俊、岩男泰、緒方晴彦、杉野吉則、北川雄光、日比紀文
    • Organizer
      第27回日本大腸検査学会総会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-20590748
  • [Presentation] 各種 Modality を用いたIBD診療の最前線2009

    • Author(s)
      日比紀文
    • Organizer
      第27回日本大腸検査学会
    • Place of Presentation
      ベルサール九段
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21249048
  • [Presentation] IL-10KOマウスにおけるマクロファージからのIL-12過剰産生機序の解明2009

    • Author(s)
      成瀬浩史、久松理一、鎌田信彦、岡本晋、井上詠、金井隆典、日比紀文
    • Organizer
      第46回日本消化器免疫学会、一般演題
    • Place of Presentation
      愛媛
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009

    • Author(s)
      久松理一、鎌田信彦、本田治樹、北爪美奈、井上詠、岡本晋、金井隆典、日比紀文
    • Organizer
      第46回日本消化器免疫学会、シンポジウム
    • Place of Presentation
      愛媛
    • Year and Date
      2009-07-23
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] MCP-1依存性腸管マクロファージサブセットの腸管免疫恒常性における役割2008

    • Author(s)
      高田康裕、久松理一、鎌田信彦、斎藤理子、高山哲朗、市川仁志、小林拓、知念寛、井上詠、岡本晋、日比紀文
    • Organizer
      第45回日本消化器免疫学会、一般演題
    • Place of Presentation
      京都
    • Year and Date
      2008-07-03
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] クローン病における腸管マクロファージの腸内細菌認識異常 -IL-23を中心とした慢性炎症サイクル-2008

    • Author(s)
      久松理一、鎌田信彦、小林拓、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
    • Organizer
      第45回日本消化器免疫学会、シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-07-04
    • Data Source
      KAKENHI-PROJECT-20200080
  • [Presentation] Mucosal CD4+T cells with high CD26 surface expression are enrichedfor memory Th1 cells and involved in the pathogenesis of inflammatorybowel disease2007

    • Author(s)
      Inoue N, Hibi T, et. al.
    • Organizer
      15th United Gastroenterology Week
    • Place of Presentation
      Paris, France
    • Year and Date
      2007-10-29
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Presentation] Mucosal CD4+ T cells with high CD26 surface expression are enriched for memory Thl cells and involved in the pathogenesis of inflammatory bowel disease2007

    • Author(s)
      Inoue N, Hibi T, et. al.
    • Organizer
      15th United Gastroenterology Week
    • Place of Presentation
      Paris,France
    • Year and Date
      2007-10-29
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Presentation] Mucosal CD^<4+>T cells with high CD26 surface expression are enriched for memory Th1 cells and involved in the pathogenesis of inflammatory bowel disease2007

    • Author(s)
      Inoue, N, Hibi, T, et. al.
    • Organizer
      15th United Gastroenterology Week
    • Place of Presentation
      Paris, France
    • Year and Date
      2007-10-29
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590677
  • [Presentation] 炎症性腸疾患診療における内視鏡検査の意義

    • Author(s)
      日比紀文
    • Organizer
      第97回日本消化器内視鏡学会関東地方会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] クローン・潰瘍性大腸炎の先進治療に向けて

    • Author(s)
      日比紀文
    • Organizer
      第30回わかば会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] IBD領域における治療の現況と展望

    • Author(s)
      日比紀文
    • Organizer
      日本化薬社内勉強会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 土屋先生の想い出と消化器免疫への提言

    • Author(s)
      日比紀文
    • Organizer
      第50回日本消化器免疫学会イブニングセミナー
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 腹部症状から診たIBDと他疾患の特徴と内視鏡診断

    • Author(s)
      日比紀文
    • Organizer
      IBD Clinical Conference
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患診療のパラダイムシフト~カプセル内視鏡の臨床応用と生物学的製剤について~

    • Author(s)
      日比紀文
    • Organizer
      目黒区医師会内科部会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患の病態解明と治療の進歩

    • Author(s)
      日比紀文
    • Organizer
      第110回日本内科学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Impact of Inflammatory Bowel Disease on Japanese patients` lives : International comparison of patients` views

    • Author(s)
      F.Ueno,Y.Nakayama,E.Hagiwara,O.Mikami,A.Inamine-Sasaki,T.Hibi
    • Organizer
      10th Congress of ECCO
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-02-18 – 2015-02-21
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 「総合診療医」とは?-日本での取り組みと消化器分野での診療の実際-炎症性腸疾患診療でのParadigm Shift

    • Author(s)
      日比紀文
    • Organizer
      中日国際消化疾病論壇
    • Place of Presentation
      北京(中国)
    • Year and Date
      2014-08-31 – 2014-09-01
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Efficacy, Safety, and Demographics Factor of Adalimumab Therapy in 1693 Japanese Crohn's Disease Patients

    • Author(s)
      Haruhiko Ogata, Mamoru Watanabe, Toshiyuki Matsui, Sadanori Abe, Shigenori Haruna, Toshifumi Hibi
    • Organizer
      DDW
    • Place of Presentation
      神戸
    • Year and Date
      2014-05-03 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患診療のパラダイムシフト~カプセル内視鏡の臨床応用と生物学的製剤について~

    • Author(s)
      日比紀文
    • Organizer
      東京消化管フォーラム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 遠位回腸検索における受動湾曲高伝達挿入部搭載細径大腸内視鏡PCF-PQ260Lの有用性の検討

    • Author(s)
      中野雅、小林拓、筋野智久、加藤裕佳子、芹澤宏、渡辺憲明、日比紀文、中里圭宏
    • Organizer
      第87回 日本消化器内視鏡学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 下痢・下血を来す疾患の診断から治療まで~その現状と新展開~

    • Author(s)
      日比紀文
    • Organizer
      港区内科医会学術講演会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Amino acids and inflammatory bowel disease-as a therapeutic target and a novel biomarker

    • Author(s)
      Toshifumi hibi
    • Organizer
      8th Asia Pacific Conference
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Percutaneous Endoscopic Gastrostomy Under Steady Pressure Automatically Controlled Endoscopy (SPACE)

    • Author(s)
      Hiroyuki Imaeda, Kiyokazu Nakajima, Naoki Hosoe, Masanori Nakahara, Shinichiro Zushi, Motohiko Kato, Kazuhiro Kashiwagi, Yasushi Matsumoto, Rieko Nakamura, Noihiro Wada, Masahiko Tsujii, Naohisa Yahagi, Toshifumi Hibi, Tetsuo Takahara.
    • Organizer
      DDW
    • Place of Presentation
      神戸
    • Year and Date
      2014-05-03 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Diffrences between treatment guidelines in IBD

    • Author(s)
      Toshifumi hibi
    • Organizer
      Falk Symposium 188
    • Place of Presentation
      Stuttgart,Germany
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患診療の黎明期・確立期と今後の展開

    • Author(s)
      日比紀文
    • Organizer
      第10回千葉IBDアフェレーシス研究会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 潰瘍性大腸炎の治療-基本から応用まで

    • Author(s)
      日比紀文
    • Organizer
      日本大腸肛門病学会第22回教育セミナー講演
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] クローン病狭窄病変に対する内視鏡的バルーン拡張術の短期・長期成績

    • Author(s)
      小林拓、長沼誠、久松理一、松岡克善、中野雅、緒方晴彦、日比紀文、金井隆典
    • Organizer
      第87回 日本消化器内視鏡学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 大きく変化した炎症性腸疾患の診療~その適切な対応は?~

    • Author(s)
      日比紀文
    • Organizer
      消化器疾患セミナー
    • Place of Presentation
      大分
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Infliximab therapy for Japanese patients with Ulcerative Colitis : Efficacy,safety,and association between serum infliximab levels and early respnse in a randomized, double-blind,placebo-controlled study

    • Author(s)
      Y.Suzuki,S.Motoya,F.Hirai,H.Ogata,H.Ito,N.Sato,K.Ozaki,M.Watanabe,T.Hibi
    • Organizer
      10th Congress of ECCO
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-02-18 – 2015-02-21
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患診療のパラダイムシフト

    • Author(s)
      日比紀文
    • Organizer
      第8回名古屋市大消化器・代謝内科フォーラム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 炎症性腸疾患に対する治療の進歩と“粘膜治癒”の意義

    • Author(s)
      日比紀文
    • Organizer
      第85回日本消化器内視鏡学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Twice-daily budesonide rectal foam induces complete mucosal healing in Japanese patients with mild to moderate Ulcerative Colitis : Results of multicentre, randomised, double-blind,placebo-controlled trial

    • Author(s)
      N.Aoyama,Y.Suzuki,H.Nishino,K.Kobayashi,F.Hirai,K.Watanabe,M,Naganuma,T.Hibi
    • Organizer
      10th Congress of ECCO
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-02-18 – 2015-02-21
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 日本における炎症性腸疾患薬物療法の現状と新たな治療薬への期待

    • Author(s)
      日比紀文
    • Organizer
      PMDAワークショップ
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 日本の炎症性腸疾患研究の歴史と将来への提言

    • Author(s)
      日比紀文
    • Organizer
      第68回大腸肛門病学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] Usefulness of faecal S100A12 in defining mucosal healing in Ulcerative Colitis

    • Author(s)
      T.Kobayashi, O.Takeuchi,S.Kuronuma,M.nakano,S.Umeda,H.Serizawa,N.Watanabe,T.Hibi.
    • Organizer
      10th Congress of ECCO
    • Place of Presentation
      バルセロナ(スペイン)
    • Year and Date
      2015-02-18 – 2015-02-21
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 生物学製剤全盛時にGMAの位置付けを問う

    • Author(s)
      日比紀文
    • Organizer
      第21回JDDW
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] AJM300, an Oral α4 Integrin Antagonist, for Active Ulcerative Colitis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2A Study

    • Author(s)
      Mamoru Watanabe, Naoki Yoshimura, Satoshi Motoya, Keiichi Tominaga, Ryuichi Iwakiri, Kenji Watanabe, Toshifumi Hibi
    • Organizer
      DDW
    • Place of Presentation
      神戸
    • Year and Date
      2014-05-03 – 2014-05-06
    • Data Source
      KAKENHI-PROJECT-24249046
  • [Presentation] 内視鏡的に特徴的な所見を観察しえた重症腸チフスの1例

    • Author(s)
      梅田智子、小林拓、筋野智久、加藤裕佳子、清水清香、中野雅、常松令、芹澤宏、渡辺憲明、土本寛二、日比紀文
    • Organizer
      第87回 日本消化器内視鏡学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-24249046
  • 1.  WATANABE Mamoru (10175127)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 23 results
  • 2.  ISHIKAWA Hiromichi (20051667)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 2 results
  • 3.  KANAI Takanori (40245478)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 38 results
  • 4.  INOUE Nagamu (00232546)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 40 results
  • 5.  IWAO Yasushi (40168547)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 13 results
  • 6.  HARUHIKO Ogata (30177117)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 7.  OKANO Hideyuki (60160694)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 8.  NAGANUMA Makoto (00265810)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OKAMOTO Susumu (70255446)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 10.  HISAMATSU Tadakazu (60255437)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 54 results
  • 11.  AISO Sadakazu (60138013)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  MAKABE Toshiaki (60095651)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  KOYASU Shigeo (90153684)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  ABE Masanori (70016624)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 17 results
  • 15.  HANDA Hiroshi (80107432)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 16.  SUEMATSU Makoto (00206385)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  NOMURA Tatsuji (10072399)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  YAJIMA Tomoharu (70306710)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 19.  EZAKI Toshihiko (20255425)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MORIMOTO Chikao (30119028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  TOSHIRO Sato (70365245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 22.  TSUCHIMOTO Kanji (70155399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  WATANABE Noriaki (80167155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SUZUKI Tatsuo (40072409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  HAMADA Yoshiki (00137994)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  ISHII Hiromasa (20051500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KUMAI Koichiro (30101984)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  FUNAKOSHI Shinsuke (20297352)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KITAJIMA Masaki (90112672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  NAKANO Masaru (50265807)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  AZUMA Toshihumi (00222612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  YAGITA Hideo (30182306)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 37.  AZUMA Miyuki (90255654)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  NAKAZAWA Stsushi (90255456)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 39.  ONO Kairo (80160901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  KOMATSU Haruko (20106678)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  田原 利行 (80276245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  新井 潤 (30306683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  合田 宣人 (00245549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  阿部 啓子 (10151094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 45.  田之倉 優 (60136786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  清水 誠 (30114507)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  MORITA Minoru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  YAGUCHI Tomonori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  SUGIYAMA Kazuo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 50.  河上 裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 51.  桜井 敏晴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 52.  斎藤 英胤
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 53.  岳野 光洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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