Hibi Toshifumi 日比紀文

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HIBI Toshifumi 日比紀文

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Researcher Number	50129623
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Affiliation (Current)	2025: 北里大学, 北里研究所病院, 特任教授
Affiliation (based on the past Project Information) *help	2013 – 2014: 慶應義塾大学, 医学部, 名誉教授 1996 – 2012: 慶應義塾大学, 医学部, 教授 2004 – 2005: 慶応義塾大学, 医学部, 教授 2000: 慶応義塾大学, 医学部, 教授 1999: 慶應義塾大学, 医学部, 内科教授 … More 1998: 慶應義塾大学, 医学部内科, 教授 1997: Keio University, School of Medicine, Professor, 医学部, 教授 1995: 慶応がんセンター, 助教授 1994: KEIO CANCER CENTER,ASSOCIATE PROFESSOR, 助教授 1994: 慶應義塾大学, 慶応がんセンター, 助教授 1993: 慶應義塾大学, がんセンター, 助教授 1992: Keio Cancer Center, 診療部長 1991: 慶応ガンセンター, 部長 1986 – 1987: 北里研究所, 病院内科, 医長 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology / Biological Sciences Except Principal Investigator Gastroenterology / Gastroenterology / Neurology / Applied pharmacology / 広領域 / Immunology
Keywords	Principal Investigator 炎症性腸疾患 / IL-7 / musashi-1 / 腸管免疫 / inflammatory bowel disease / 幹細胞 / 大腸癌 / サイトカイン / トランスジェニックマウス / mucosal immunology … More / 粘膜再生療法 / SP細胞 / 腸管上皮 / 潰瘍性大腸炎 / ノックアウトマウス / IL-7レセプター / regeneration of mucosa / stem cell / intestinal epithelial cell / T lymphocytes / knock-out mice / cytokine / transgenic mice / interleukin-7 receptor / interleukin-7 / HIV / WNT / β-catenin / Wntシグナル / side population cell / in vivo tissue staining / LHK antibody / plasma / biomagnetic probe / liposome / heme / colon cancer / バイオマグネティックプローブ / 生体内組織染色 / プラズマ / ヘム / 磁性体 / リポソーム / Cholera toxin / cytotoxic Tlymphcyte / transgenic mouse / oral Immunization / AIDS / SIV / コレラトキシン / 細胞障害性T細胞 / 経口免疫 / エイズ / fibrocyte / 腸管線維化 / クローン病 / 大腸がん / 下部消化管 / 下部消化管学 / 生物学的製剤 / 分指標的 / フェライト粒子 / 免疫記憶 / NK細胞 / 腸内細菌 / マクロファージ / dysplasia / ELISA / p53 / サーベイランス / GFP / ジフテリア毒素 / drug delivery system / ヒト第6番染色体 / 欠失地図 … More Except Principal Investigator 炎症性腸疾患 / inflammatory bowel disease / 潰瘍性大腸炎 / Th1 / Crohn's disease / IgG Fc binding protein / Crohn病 / 腸管免疫 / 大腸癌 / 自然免疫 / クローン病 / 腸内細菌 / HIV / Cbl-b / B7h / bone marrow transplantation / transdifferentiation / cell fusion / 制御性T細胞 / drug delivery system / SAP / Th2 / intestinal microflora / モデルマウス / フローラ / DNA / mucin / mucosal defense / ムチン / 粘膜防御 / immunology / 樹状細胞 / トランスレーショナルリサーチ / 生体分子 / 腸内フローラ / 免疫学 / mucosal immunology / トランスジェニックマウス / antigen / 抗原 / 抗体 / ハイパーサーミア / 抗ガン剤 / CD4 / ulcerative colitis / AIDS / cDNA / retrovirus / thymus / myasthenia graves / 逆転写酵素 / HTLV / ウイルス遺伝子のクローニング / cNDA / レトロウイルス / 胸腺 / 重症筋無力症 / DSS coliti / interleulcin-10 gene deficient mice / Germ-free / 慢性腸炎 / DSS腸炎 / IL-10ノックアウトマウス / immunoregulatory therapy / CD8 T cell / homeostasis / regulatory T cell / epithelial cell / Cb1-b / 抑制性CD8^+T細胞 / ホメオスタシス / 免疫統御療法 / 抑制性CD8T細胞 / ホメオシタシス / 大腸上皮 / bonemarrow transplantation / translational research / biological molecule / intestinal bacteria / プロバイオティクス / マウス大腸炎モデル / メモリー細胞 / 細菌 / 粘膜制御 / T cell / IBD / T細胞 / natural killer T cell / dendritic cell / NKT細胞 / stem cell / disease model mice / NOG mice / 幹細胞 / NOGマウス / Transgenic mice / Cell transfer / Probiotics / Ulcerative colitis / Antigen-specific / murine model / inflammatory bowel diseases / 自己免疫疾患 / 慢性大腸炎モデル / 単クローン / 腸管粘膜免疫 / 調節製T細胞 / 慢性大腸炎 / 調節性T細胞 / 細胞移入 / プロバイオテクス / 抗原特異性 / マウスモデル / Ferrite nanobeads / Anticancer drug / Hyperthermia / MRI contrast agent / Bio-sensing / Bio-screening / Magnetic beads / CEA抗体 / IgG抗体 / フェライトナノビーズ / MMI造影 / GMA / フェライト粒子 / MRI造影剤 / DNA検出 / 磁性ビーズ / フェライト・ナノビーズ / MRI造影 / バイオセンシング / バイオスクリーニング / 磁気ビーズ / intestinal mucosal immunology / isolated lymphoid follicles / cryptopatch / secretory IgA antibody / intestinal T cells / γδ T cells / intestinal flora / dietary substances / 一酸化炭素 / Heme oxygenase / インターロイキン15 / 腸管上皮細胞 / 腸内常在フローラ / 分泌型lgA抗体 / 腸管孤立リンパ小節 / 腸管上皮細胞間T細胞 / 経口免疫寛容 / 孤立リンパ小節 / クリプトパッチ / 分泌型IgA抗体 / 腸管上皮細胞T細胞 / γδT細胞 / 食品 / GTP-bindinK protein / Rho-fatnily GTPases / Racl / metastasis / colon cancer / GTP結合タンパク質 / Rhoファミリー / Rac1 / 転移 / diphteria toxin / T lymphocytes / knock-out mice / interleukin-7 receptor / interleukin-7 / ノックアウトマウス / ジフテリア毒素 / IL-7レセプター / IL-7 / antibody / magnetic bioprobe / hyperthermia / anticancer drug / IGG antibody / ferrite beads / medical magnetic beads / 磁気分離 / 生体高分子 / CMC / BSA / スピネル型 / バイオ高分子 / バイオ・リガンド / マグネタイト / 蛍光磁性プローブ / 磁性バイオプローブ / IGG抗体 / フェライト超微粒子 / 医用磁性ビーズ / LASER / early colon cancer / autofluolescence / 異型上皮 / 自然蛍光 / レーザー / SOLUBLE CD4 / MONOCLONAL ANTIBODY / CYTOTOXIC T LYMPHOCYTE / INTESTINAL MUCOSAL LYMPHOCYTE / 腸管上皮間リンパ球 / 可溶性CD4 / モノクローナル抗体 / 細胞障害性T細胞 / 腸管粘膜内リンパ球 / エイズ / animal model of colitis / hapten / Crhon's disease / 大腸特異抗原 / 実験腸炎 / 実験大腸炎 / ハプテン / 内視鏡 / 清瘍性大腸炎 / 早期発見 / 内神鏡 / dysplasia / p53 / ELISA / サーベイランス / 細胞内寄生菌 / オートファジー / マクロファージ / 粘膜免疫 / 癌関連遺伝子 / 腸管上皮再生 / 細胞接着 / 大腸癌転移 / 腸管上皮分化 / 消化器学(食道、胃、小腸、大腸) / 免疫抑制剤 / TPMT遺伝子多型 / 腸管粘膜防御機構 / IgGFcレセプター / CTL / 経口ワクチン / SIV Less

Molecular characterization of Colitis Associated CancerPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The role of fibrocyte in intestinal fibrosis and screening of anti-fibrotic therapy targeting fibrocyte.Principal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
特異抗体結合フェライトスーパービーズによる免疫標的療法の創成Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Investigation of intestinal macrophage in contribution to gut immune homeostasis and its disruption in Crohn's diseasePrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Elucidation of intestinal mucosal immune system through the intracellular processing mechanisms of bacteria and its application for novel therapy of inflammatory bowel disease
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
- Research Field
  
  Immunology
- Research Institution
  Keio University
Establishment of cancer surveillance using serum anti-p53 antibody in patients with ulcerative colitis
- Principal Investigator
  
  IWAO Yasushi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Analysis of intestinal epithelial differentiation and mechanisms of colon cancer metastasis in Cdx-induced human Colo 205 cells
- Principal Investigator
  
  EZAKI Toshihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
潰瘍性大腸炎合併大腸癌に対する新しいサーベイランス法の確立-抗p53抗体の有用性Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
The establishment of bacteria antigen-specific T cell transgenic mice develop spontaneous chronic colitis, and the development of inhibitory probiotics for the treatment of inflammatory bowel diseases
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
The role of bone marrow-derived cells in generation of gut epithelium
- Principal Investigator
  
  YAJIMA Tomoharu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY
The maintenance of mucosal homeostasis by regulating functional B7h on the colonic epithelial cells and development a cure for inflammatory bowel disease.
- Principal Investigator
  
  NAKAZAWA Stsushi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY
Involvement of intestinal flora in the pathogenesis of chronic'colitis
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Identification of gastrointestinal epithelial stem cell and development of regeneration therapy for LBDPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY
Exploitation of a novel therapy for inflammatory bowel diseases by modulating SAP, a T cell specific adaptor molecule
- Principal Investigator
  
  OKAMOTO Susumu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Novel therapeutic strategy for ulcerative colitis by hard capsule contained with IgG Fc binding protein
- Principal Investigator
  
  OGATA Haruhiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
腸管上皮幹細胞の純化と炎症性腸疾患に対する新しい再生治療の開発Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Keio University
Applying ferrite nanobeads to medical diagnosis, therapy and analysis
- Principal Investigator
  
  ABE Masanori
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tokyo Institute of Technology
Establishment of transgenic mice that recognize bacteria specific antigen and develop spontaneous colitis under specific pathogen free condition.
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Medical and Dental University
Development of novel mouse model of human Crohn's disease
- Principal Investigator
  
  INOUE Nagamu
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of novel therapy targeting dendritic cells for Crohn's disease
- Principal Investigator
  
  IWAO Yasushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
遺伝子組換えフローラ大腸菌含有ハードカプセルを用いた漫性大腸炎に対する治療戦略Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Identification of gastrointestinal epithelial stem cell and development of regeneration therapy for IBDPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Distribution and characterization of IgG Fc binding protein in various mucin producing cells
- Principal Investigator
  
  OGATA Haruhiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY
遺伝子多型性の解析に基づいた炎症性腸疾患に対する新しい免疫抑制剤投与法の開発
- Principal Investigator
  
  NAGANUMA Makoto
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
炎症を発生母地とした大腸癌に関与する新規癌抑制遺伝子の単離Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Regulation of the cancer cell motility by Racl GTPase: implications for metastasis of colon cancer
- Principal Investigator
  
  NAKANO Masaru
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  TOKYO DENTAL COLLEGE
Investigation of immuno-regulatory competency of dietary substances and its application for our own beneficial ends
- Principal Investigator
  
  ISHIKAWA Hiromichi
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  Keio University
Magnetic probe with ferrite couples to bioligands for diagnostic and clinical uses
- Principal Investigator
  
  ABE Masanori
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Tokyo Institute of Technology
New therapy targeting IL-7 receptor positive lymphocytes for chronic intestinal inflammation
- Principal Investigator
  
  NAGANUMA Makoto
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Development of novel diagnostic device using lesion-orieinted biomagnetic probePrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
腸管粘膜内IL-7レセプター腸性細胞を標的とした新しい慢性大腸炎治療法の開発Principal Investigator
- Principal Investigator
  
  日比紀文
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
New therapy for chronic intestinal inflammation by regulating mucosal immune responsesPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
New therapy for intestinal inflammation by regulating mucosal immune responsesPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
腸管粘膜防御機構における腸管上皮細胞IgGFcレセプター(結合蛋白)の解析
- Principal Investigator
  
  田原利行
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
経口ワクチン開発のための腸管内HIV特異的細胞傷害性T細胞に関する基礎的研究
- Principal Investigator
  
  KANAI Takanori
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Detection of neoplastic lesion and dysplasia using laser beam under the endoscope
- Principal Investigator
  
  IWAO .yasushi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
Induction of cytotoxic Tlymphocyters in the intestinal mucosa by oral immunization of SIV gag or env peptide conjugated with chorela toxinPrincipal Investigator
- Principal Investigator
  
  HIBI Toshifumi, 渡辺守
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Keio University
ACTIVE IMMUNE THERAPY FOR THE TREATMENT OF AIDS
- Principal Investigator
  
  WATANABE Mamoru
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KEIO UNIVERSITY
Investigations of immunological disturbance in ulcerative colitis and animal models of inflammatory bowel disease.
- Principal Investigator
  
  TSUCHIMOTO Kanji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  KITASATO INSTITUTE
Research for retroviruses in thymus cells of myasthenia gravis and their involvement in the pathogeneses of myasthenia gravis
- Principal Investigator
  
  ONO Kairo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  The Kitassto Institute

[Book] ドクターサロン　実地診療における炎症性腸疾患2014
- Author(s)
  日比紀文
- Publisher
  杏文堂
- Data Source
  KAKENHI-PROJECT-24249046
[Book] 内科　潰瘍性大腸炎2014
- Author(s)
  日比紀文、小林拓、中野雅
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24249046
[Book] INTESTINE　大腸内視鏡（4）超拡大内視鏡2014
- Author(s)
  小林拓、長沼誠、緒方晴彦、日比紀文、金井隆典
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24249046
[Book] G.I.Research　わたしの研究歴2014
- Author(s)
  日比紀文
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24249046
[Book] 日本成人病（生活習慣病）学会準機関誌　潰瘍性大腸炎の内科治療-近年の変化2014
- Author(s)
  日比紀文、小林拓、中野雅
- Publisher
  日本成人病（生活習慣病）学会
- Data Source
  KAKENHI-PROJECT-24249046
[Book] INTESTINE　特集「日常遭遇する大腸炎の鑑別－内視鏡を中心に」「序説」2014
- Author(s)
  日比紀文
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24249046
[Book] 薬局　潰瘍性大腸炎（エキスパートに学ぶ！薬物治療における直腸投与製剤の位置づけと活用のポイント①）2014
- Author(s)
  日比紀文、小林拓、中野雅、渡辺憲明
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24249046
[Book] INTESTINE　特集　腸管ベーチェット病と単純性潰瘍　腸管ベーチェット病の治療-改訂コンセンサスを中心に2014
- Author(s)
  久松　理一、上野　文昭、日比　紀文
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-24249046
[Book] IBD Research　IBD診療に使用されるインデックスの今後の展望2014
- Author(s)
  小林拓、筋野智久、加藤裕佳子、中野雅、日比紀文
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24249046
[Book] Rheumatology Clinical Research　特集　生物学的製剤の適応があるリウマチ類縁疾患　炎症性腸疾患2014
- Author(s)
  日比紀文　小林拓　中野雅
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-24249046
[Book] 炎症性腸疾患2012
- Author(s)
  久松理一、日比紀文
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-21249048
[Book] G.I.Research IBDと炎症性サイトカイン-Th17-2011
- Author(s)
  久松理一、日比紀文
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21249048
[Book] 潰瘍性大腸炎消化器疾患ガイドライン2011
- Author(s)
  久松理一、日比紀文
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-21249048
[Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療2010
- Author(s)
  日比紀文、久松理一
- Total Pages
  213
- Publisher
  羊土社出版
- Data Source
  KAKENHI-PROJECT-21249048
[Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療2010
- Author(s)
  日比紀文、久松理一
- Total Pages
  340
- Publisher
  医学書院出版
- Data Source
  KAKENHI-PROJECT-21249048
[Book] 炎症性腸疾患の鑑別診断(日比紀文編)(炎症性腸疾患)2010
- Author(s)
  日比紀文
- Total Pages
  340
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21249048
[Book] 消化器BookシリーズNo.2特集:炎症性腸疾患の診断・治療(久松理一、日比紀文編)2010
- Author(s)
  日比紀文
- Total Pages
  213
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] TGF-β1 in tumor microenvironments induces immunosuppression in the tumors and sentinel lymph nodes and promotes tumor progression2014
- Author(s)
  Nakamura S, Yaguchi T, Kawamura N, Kobayashi A, Sakurai T, Higuchi H, Takaishi H, Hibi T, Kawakami Y
- Journal Title
  
  J Immunother
  
  Volume: 37(2) Issue: 2 Pages: 63-72
- DOI
  10.1097/cji.0000000000000011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23240128, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24591635, KAKENHI-PROJECT-25830122
[Journal Article] A large-scale,prospective,observational study of leukocytapheresis for ulcerative colitis:treatment outcomes of 847 patients in clinical practice2014
- Author(s)
  Yokoyama Y, Matsuoka K, Kobayashi T, Sawada K, Fujiyoshi T, Ando T, Ohnishi Y, Ishida T, Oka M, Yamada M, Nakamura T, Ino T, Numata T, Aoki H, Sakou J, Kusada M, Maekawa T, Hibi T.
- Journal Title
  
  Journal of Crohn's and Colitis
  
  Volume: 8 Issue: 9 Pages: 981-91
- DOI
  10.1016/j.crohns.2014.01.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Free cholesterol accumulation in hepatic stellate cells: Mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice2014
- Author(s)
  Tomita, K. Teratani, T. Suzuki, T. Shimizu, M. Sato, H. Narimatsu, K. Okada, Y. Kurihara, C. Irie, R. Yokoyama, H. Shimamura, K. Usui, S. Ebinuma, H. Saito, H. Watanabe, C. Komoto, S. Kawaguchi, A. Nagao, S. Sugiyama, K. Hokari, R. Kanai, T. Miura, S. Hibi, T.
- Journal Title
  
  Hepatology
  
  Volume: 59 Issue: 1 Pages: 154-169
- DOI
  10.1002/hep.26604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24590993, KAKENHI-PROJECT-24790719
[Journal Article] The 2nd edition of consensus statements for the diagnosis and management of intestinal Behcet's disease: indication of anti-TNFα monoclonal antibodies.2014
- Author(s)
  Hisamatsu T, Ueno F, Matsumoto T, Kobayashi K, Koganei K, Kunisaki R, Hirai F,Nagahori M, Matsushita M, Kobayashi K, Kishimoto M, Takeno M, Tanaka M, Inoue N, Hibi T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 49(1) Issue: 1 Pages: 156-62
- DOI
  10.1007/s00535-013-0872-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591443, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590937, KAKENHI-PROJECT-26461469
[Journal Article] Macrophages and dendritic cells emerge in the liver during intestinal inflammation and predjspose the liver to inflammation.2014
- Author(s)
  Mikami Y, Mizuno S, Nakamoto N, Hayashi A, Sujino T, Sato T, Kamada N, Matsuoka K, Hisamatsu T, Ebinuma H, Hibi T, Yoshimura A, Kanai T.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: 1-1
- DOI
  10.1371/journal.pone.0084619
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24390190, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] Use of capsule endoscopy in patients with Crohn's disease in Japan: a multicenter survey.2014
- Author(s)
  Esaki M, Matsumoto T, Watanabe K, Arakawa T, Naito Y, Matsuura M, Nakase H, Hibi T, Matsumoto T, Nouda S, Higuchi K, Ohmiya N, Goto H, Kurokawa S, Motoya S, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29(1) Issue: 1 Pages: 96-101
- DOI
  10.1111/jgh.12411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590941
[Journal Article] Surveillance using trimodal imaging endoscopy after endoscopic submucosal dissection for superficial gastric neoplasia.2014
- Author(s)
  Imaeda H, Hosoe N, Kashiwagi K, Ida Y, Nakamura R, Suzuki H, Saito Y, Yahagi N, Iwao Y, Kitagawa Y, Hibi T, Ogata H, Kanai T.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20(43) Issue: 43 Pages: 16311-7
- DOI
  10.3748/wjg.v20.i43.16311
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25293178, KAKENHI-PROJECT-26670065
[Journal Article] Efficacy and safety of adalimumab in Japanese patients with moderately to severely active ulcerative colitis.2014
- Author(s)
  Suzuki Y,Motoya S,Hanai H,Matsumoto T,Hibi T,Robinson AM,Mostafa NM,Chao J,Arora V,Camez A,Thakkar RB,Watanabe M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 49 Issue: 2 Pages: 283-94
- DOI
  10.1007/s00535-013-0922-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Modified bowel preparation regimen for use in second-generation colon capsule endoscopy in patients with ulcerative colitis2014
- Author(s)
  Usui S, Hosoe N, Matsuoka K, Kobayashi T, Nakano M, Naganuma M, Ishibashi Y, Kimura K, Yoneno K, Kashiwagi K, Hisamatsu T, Inoue N, Serizawa H, Hibi T, Ogata H, Kanai T.
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 26(5) Issue: 5 Pages: 665-72
- DOI
  10.1111/den.12269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-25460960
[Journal Article] Endoscopic imaging of parasites in the human digestive tract.2014
- Author(s)
  Hosoe N, Ogata H, Hibi T.
- Journal Title
  
  Parasitol Int
  
  Volume: 63(1) Issue: 1 Pages: 216-20
- DOI
  10.1016/j.parint.2013.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis.2013
- Author(s)
  Sandborn WJ, Feagan BG, Marano C, Zhang H, Strauss R, Johanns J, Adedokun OJ, Guzzo C, Colombel JF, Reinisch W, Gibson PR, Collins J, Järnerot G, Hibi T, Rutgeerts P; PURSUIT-SC Study Group.
- Journal Title
  
  Gastroenterology
  
  Volume: 146(1) Issue: 1 Pages: 85-95
- DOI
  10.1053/j.gastro.2013.05.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Musashi-1 post-transcriptionally enhances phosphotyrosine-binding domain- containing m-Numb protein expression in regenerating gastric mucosa.2013
- Author(s)
  Tetsufumi Takahashi
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: 1-13
- DOI
  10.1371/journal.pone.0053540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300169, KAKENHI-PROJECT-22600011, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24500447, KAKENHI-PROJECT-24601016, KAKENHI-PROJECT-24659103, KAKENHI-PROJECT-25293178
[Journal Article] TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.2013
- Author(s)
  Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  Immunology
  
  Volume: 139(1) Issue: 1 Pages: 19-29
- DOI
  10.1111/imm.12045
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] A Single Strain of Clostridium butyricum Induces Intestinal I L-10-Producing Macrophages to Suppress Acute Exlperimental Colitis in Mice.2013
- Author(s)
  Hayashi A, Sato T, Kamada N, Mikami Y, Matsuoka K, Hisamatsu T, Hlbi T, Roers A, Yagita H, Ohteki T, Yoshimura A, Kanai T.
- Journal Title
  
  Cell Host Microbe
  
  Volume: 13 Issue: 6 Pages: 711-22
- DOI
  10.1016/j.chom.2013.05.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion2013
- Author(s)
  Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] C-reactive protein is an indicator of serum infliximab level in predicting loss of response in patients with Crohn's disease.2013
- Author(s)
  Hibi T, Sakuraba A, Watanabe M, Motoya S, Ito H, Sato N, Yoshinari T, Motegi K, Kinouchi Y, Takazoe M, Suzuki Y, Matsumoto T, Kawakami K, Matsumoto T, Hirata I, Tanaka S, Ashida T, Matsui T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49(2) Issue: 2 Pages: 254-62
- DOI
  10.1007/s00535-013-0807-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice2013
- Author(s)
  Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T.
- Journal Title
  
  Immunol Lett.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Continuous low-dose irradiation by I-125 seeds induces apoptosis of gastric cancer cells regardless of histological origin.2013
- Author(s)
  Takabayashi K, Kashiwagi K, Kawata T, Sato T, Matsuoka K, Hisamatsu T, Takaishi H, Hibi T, Ogata H, Yahagi N, Kitagawa Y, Shigematsu N, Kanai T.
- Journal Title
  
  Cancer Biol Ther.
  
  Volume: 15(1) Issue: 1 Pages: 81-8
- DOI
  10.4161/cbt.26610
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] Mucosal healing with oral tacrolimus is associated with favorable medium- and long-term prognosis in steroid-refractory/dependent ulcerative colitis patients.2013
- Author(s)
  Miyoshi J, Matsuoka K, Inoue N, Hisamatsu T, Ichikawa R, Yajima T, Okamoto S, Naganuma M, Sato T, Kanai T, Ogata H, Iwao Y, Hibi
- Journal Title
  
  J Crohns Colitis
  
  Volume: 7 Issue: 12 Pages: e609-e614
- DOI
  10.1016/j.crohns.2013.04.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] Dendritic cells administered intrarectally penetrate the intestinal barrier to break intestinal tolerance via Th2-medeiated colitis in mice.2013
- Author(s)
  Handa T, Kanai T, Sato T, Mikami Y, Sujino T, Hayashi. A, Mizuno S, Matsumoto A, Hisamatsu T, Hibi T.
- Journal Title
  
  Immunology Letters
  
  Volume: 150 Issue: 1-2 Pages: 123-9
- DOI
  10.1016/j.imlet.2013.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25670372
[Journal Article] IL-22-Producing RORyt-Dependent Innate Lymphoid Cells Play a Novel Protective Role in Murine Acute Hepatitis.2013
- Author(s)
  Matsumoto A, Kanai T, Mikami Y, Chu PS, Nakamoto N, Ebinuma H, Saito H, Sato T, Yagita H, Hibi T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 4 Pages: e62853-e62853
- DOI
  10.1371/journal.pone.0062853
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PUBLICLY-24112523, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24689036, KAKENHI-PROJECT-25253080, KAKENHI-PROJECT-25670372
[Journal Article] C-C motif chemokine receptor 9 positive macrophages activate hepatic stellate cells and promote liver fibrosis in mice.2013
- Author(s)
  Chu PS, Nakamoto N, Ebinuma H, Usui S, Saeki K, Matsumoto A, Mikami Y, Sugiyama K, Tomita K, Kanai T, Saito H, Hibi T.
- Journal Title
  
  Hepatology
  
  Volume: 58 Issue: 1 Pages: 337-350
- DOI
  10.1002/hep.26351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590551, KAKENHI-PROJECT-23591001, KAKENHI-PROJECT-24249046
[Journal Article] CCR2 knockout exacerbates cerulein-induced chronic pancreatitis with hyperglycemia via decreased GLP-1 receptor expression and insulin secretion.2013
- Author(s)
  Nakamura Y, Kanai T, Saeki K, Takabe M, Irie J, Miyoshi J, Mikami Y, Teratani T, Suzuki T, Miyata N, Hisamatsu T, Nakamoto N, Yamagishi Y, Higuchi H, Ebinuma H, Hozawa S, Saito H, Itoh H, Hibi T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 304 Issue: 8 Pages: G700-G707
- DOI
  10.1152/ajpgi.00318.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-24659374
[Journal Article] Efficacy and tolerability of oral budesonide in Japanese patients with active Crohn's disease: a multicentre, double-blind, randomized, parallel-group Phase II study2013
- Author(s)
  Suzuki Y, Motoya S, Takazoe M, Kosaka T, Date M, Nii M, Hibi T.
- Journal Title
  
  J Crohns Colitis
  
  Volume: 7(3) Issue: 3 Pages: 239-47
- DOI
  10.1016/j.crohns.2012.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046
[Journal Article] Bile acids induce monocyte differentiation toward interleukin-12 hypo-producing dendritic cells via a TGR5-dependent pathway2012
- Author(s)
  Ichikawa R, Hisamatsu T, Hibi T, et al.
- Journal Title
  
  Immunology
  
  Volume: 136(2) Pages: 153-162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14+ macrophage activation2012
- Author(s)
  Uo M, Hisamatsu T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K,Matsuoka K, Kanai T, Hibi T
- Journal Title
  
  Gut.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells.2012
- Author(s)
  Nishida A, Nagahama K, Imaeda H, Ogawa A, Lau CW, Kobayashi T, Hisamatsu T, Preffer FI, Mizoguchi E, Ikeuchi H, Hibi T, Fukuda M, Andoh A, Blumberg RS, Mizoguchi A.
- Journal Title
  
  J Exp Med.
  
  Volume: 209(13) Issue: 13 Pages: 2383-94
- DOI
  10.1084/jem.20112631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24790852
[Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice.2012
- Author(s)
  Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 143 Issue: 5 Pages: 1288-1297
- DOI
  10.1053/j.gastro.2012.07.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-22590763, KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590933, KAKENHI-PROJECT-24659374, KAKENHI-PROJECT-24659375
[Journal Article] Activated Hepatic Stellate Cells Mediate the Differentiation of Macrophages.2012
- Author(s)
  Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, and Hibi T.
- Journal Title
  
  Hepatology Research.
  
  Volume: Epub ahead of print Issue: 6 Pages: 658-669
- DOI
  10.1111/j.1872-034x.2012.01111.x
- NAID
  10031194568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Anticoagulation therapy dramatically improved severe sigmoiditis with findings resembling inflammatory bowel disease, which was caused by mesenteric venous thrombosis.2012
- Author(s)
  Mikami Y, Kanai T, Iwasaki E, Naganuma M, Yamagishi Y, Shimoda M, Matsuoka K, Hisamatsu T, Iwao Y, Ogata H, Nakatsuka S, Mukai M, Hibi T.
- Journal Title
  
  Clinical Journal of Gastroenterology.
  
  Volume: 5 Pages: 377-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Immune aspects of the pathogenesis of inflammatory bowel disease.2012
- Author(s)
  Hisamatsu T, Kanai T, Mikami Y, Yoneno K, Matsuoka K, Hibi T.
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 137 Issue: 3 Pages: 283-297
- DOI
  10.1016/j.pharmthera.2012.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-24659374
[Journal Article] Dysregulated balance of retinoid-related orphan receptor _Yt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis.2012
- Author(s)
  Kimura K, Kanai T, Hayashi A, Mikami Y, Sujino T, Mizuno S, Handa T, Matsuoka K, Hisamatsu T, Sato T, Hibi T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 427 Issue: 4 Pages: 694-700
- DOI
  10.1016/j.bbrc.2012.09.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05920, KAKENHI-PROJECT-23590949, KAKENHI-PROJECT-24659374
[Journal Article] Is the dendritic cell a missing piece in the pathogenesis model of post-infectious irritable bowel syndrome?-Editorial for "Characteristics of intestinal lamina propria dendritic cells in a mouse model of postinfectious irritable bowel syndrome.2012
- Author(s)
  Hisamatsu T, Hibi T
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 27 Pages: 847-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Mucosal CXCR4+ IgG plasma cells contribute to the pathogenesis of human ulcerative colitis through FcγR-mediated CD14+ macrophage activation.2012
- Author(s)
  Uo M, Hisamatsu T, Miyoshi J, Kaito D, Yoneno K, Kitazume MT, Mori M, Sugita A, Koganei K,Matsuoka K, Kanai T, Hibi T.
- Journal Title
  
  Gut.
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Immune aspects of the pathogenesis of inflammatory bowel disease2012
- Author(s)
  Hisamatsu T, Kanai T, Yohei Mikami, Yoneno K, Matsuoka K, Hibi T
- Journal Title
  
  Pharmacol Ther.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] A Case of Intestinal Behçet's Disease Treated with Infliximab Monotherapy Who Successfully Maintained Clinical Remission and Complete Mucosal Healing for Six Years.2012
- Author(s)
  Maruyama Y, Hisamatsu T, Matsuoka K, Naganuma M, Inoue N, Ogata H, Iwao Y, Kanai T, Hibi T.
- Journal Title
  
  Intern Med.
  
  Volume: 51(16) Pages: 2125-9
- NAID
  130002062319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] T-helper 17 and Interleukin-17-Producing Lymphoid Tissue Inducer-Like T Cells Make Different Contributions to Colitis in Mice2012
- Author(s)
  Ono Y, Kanai T, Sujino T, Nemoto Y, Kanai Y, Mikami Y, Hayashi A, Matsumoto A, Takaishi H, Ogata H, Matsuoka K, Hisamatsu T, Watanabe M, Hibi T .
- Journal Title
  
  Gastroenterology.
  
  Volume: 143 Pages: 1288-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Dysregulated balance of retinoid-related orphan receptor γt-dependent innate lymphoid cells is involved in the pathogenesis of chronic DSS-induced colitis2012
- Author(s)
  Kimura K, Kanai T, Hayashi A, Mikami Y, Sujino T, Mizuno S, Handa T, Matsuoka K, Hisamatsu T, Sato T Hibi T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 427 Pages: 694-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] A Case of Intestinal Behcet's Disease Treated with Infliximab Monotherapy Who Successfully Maintained Clinical Remission and Complete Mucosal Healing for Six Years2012
- Author(s)
  Maruyama Y, Hisamatsu T, Matsuoka K, Naganuma M, Inoue N, Ogata H, Iwao Y, Kanai T, Hibi T
- Journal Title
  
  Intern Med
  
  Volume: 51 Pages: 2125-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Regulatory T Cells Suppress Development of Colitis, Blocking Differentiation of T-Helper 17 Into Alternative T-Helper 1 Cells2011
- Author(s)
  Sujino T, Kanai T, Hisamatsu T, Hibi T, et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 141(3) Pages: 1014-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 総説『クローン病の長期予後について考える』2011
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 108巻3号 Pages: 373-380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 炎症性腸疾患におけるアミノ酸補給の意義2011
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  日本消化吸収学会雑誌
  
  Volume: 33(3) Pages: 352-361
- NAID
  10029066191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Oncogenic Smad3 signaling induced by chronic inflammation is an early event in ulcerative colitis-associated carcinogenesis.2011
- Author(s)
  Kawamata S, Matsuzaki K, Murata M, Seki T, Matsuoka K, Iwao Y, Hibi T, Okazaki K
- Journal Title
  
  Inflamm Bowel Dis 17(3)
  
  Pages: 683-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] 特集:小腸疾患:診断と治療の進歩II.診療の進歩6.Crohn病2011
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 第100巻第1号 Pages: 85-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Ectopic expression of blood type antigens in inflamed mucosa with higher incidence of FUT2 secretor status in colonic Crohn's disease2011
- Author(s)
  Miyoshi J, Hisamatsu T, Kanai T, Hibi T, et al.
- Journal Title
  
  J Gastroenterol
  
  Volume: 46(9) Pages: 1056-1063
- NAID
  10029706720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 特集:小腸疾患:診断と治療の進歩II.診療の進歩62011
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  Crohn病日本内科学会雑誌
  
  Volume: 第100巻第1号 Pages: 85-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages.2011
- Author(s)
  Naruse H, Hisamatsu T, Yamauchi Y, Chang JE, Matsuoka K, Kitazume MT, Arai K, Ando S, Kanai T, Kamada N, Hibi T.
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: Feb24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Successful treatment of a large hyperplastic polyp in the jejunum by using single-balloon enteroscopy.2011
- Author(s)
  Nakamura S, Imaeda H, Sujino T, Hosoe N, Naganuma M, Ebinuma H, Okamoto S, Nishizawa T, Takahashi M, Iwao Y, Kameyama K, Mukai M, Ogata H, Hibi T.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity2011
- Author(s)
  Kobayashi T, Hisamatsu T, Hibi T, Rothman PB, Kashiwada M
- Journal Title
  
  J Immunol
  
  Volume: 186(8) Pages: 4649-4655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages Clin Exp Immunol2011
- Author(s)
  Naruse H, Hisamatsu T, Kanai T, Hibi T, et al.
- Volume
  164(1)
- Pages
  137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Rothman PB, Kashiwada M, Plevy SE.NFIL3 Is a Regulator of IL-12 p40 in Macrophages and Mucosal Immunity2011
- Author(s)
  Kobayashi T, Hisamatsu T, Hibi T, et al, 他8名、11番目
- Journal Title
  
  J Immunol
  
  Volume: 186(8) Pages: 4649-4655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] ヒト腸管自然免疫担当細胞による恒常性維持と炎症性腸疾患におけるその破綻2011
- Author(s)
  久松理一、鎌田信彦、日比紀文
- Journal Title
  
  細胞工学(監修清野宏)(秀潤社)
  
  Volume: Vol.30 No.4 Pages: 366-370
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 炎症性腸疾患におけるアミノ酸補給の意義2011
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  日本消化吸収学会雑誌総説
  
  Volume: (in press)
- NAID
  10029066191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] ヒト腸管自然免疫担当細胞による恒常性維持と炎症性腸疾患におけるその破綻2011
- Author(s)
  久松理一、鎌田信彦、日比紀文
- Journal Title
  
  細胞工学監修清野宏秀潤社
  
  Volume: Vol.30 No.4 Pages: 366-370
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Intracellular bacteria recognition contributes to maximal interleukin (IL)-12 production by IL-10-deficient macrophages2011
- Author(s)
  Naruse H, Hisamatsu T, Kanai T, Hibi T, et al, 他7名、11番目
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 164(1) Pages: 137-144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Target biopsy or step biopsy? Optimal surveillance for ulcerative colitis : a Japanese nationwide randomized controlled trial.2011
- Author(s)
  Watanabe T, Ajioka Y, Matsumoto T, Tomotsugu N, Takebayashi T, Inoue E, Iizuka B, Igarashi M, Iwao Y, Ohtsuka K, Kudo SE, Kobayashi K, Sada M, Matsumoto T, Hirata I, Murakami K, Nagahori M, Watanabe K, Hida N, Ueno F, Tanaka S, Watanabe M, Hibi T
- Journal Title
  
  J Gastroenterol 46Suppl 1
  
  Pages: 11-6
- NAID
  10029029994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] 特集:生体防御と自然免疫-最近の知見Workshop実臨床のトピックスIBD発症進展における自然免疫の役割2010
- Author(s)
  久松理一, 日比紀文
- Journal Title
  
  侵襲と免疫メジカルビュー社
  
  Volume: Vol.19 No.2 Pages: 39-42
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Clinical results of observation of the upper gastrointestinal tract by transgastrostomic endoscopy using an ultrathin endoscope.2010
- Author(s)
  Imaeda H, Hosoe N, Nakamizo H, Kashiwagi K, Suzuki H, Saito Y, Suganuma K, Ida Y, Matsuzaki J, Iwasaki E, Iwao Y, Ogata H, Hibi T.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 25 Pages: 1850-1854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
- Journal Title
  
  J Immunol
  
  Volume: 184(5) Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T
- Journal Title
  
  Eur J Immunol 40(9)
  
  Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. 16(4)
  
  Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Imbalance of NKp44(+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T
- Journal Title
  
  J Immunol 184(5)
  
  Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Rapid endoscopic improvement is important for 1-year avoidance of colectomy but not for the long-term prognosis in cyclosporine A treatment for ulcerative colitis.2010
- Author(s)
  Kobayashi T, Naganuma M, Okamoto S, Hisamatsu T, Inoue N, Ichikawa H, Takayama T, Saito R, Sujino T, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 45(11)
  
  Pages: 1129-37
- NAID
  10027699761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] アミノ酸と免疫2010
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  Functinal Food
  
  Volume: 第11号Vol.4 No.1 Pages: 16-22
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] MyD88-dependent pathway accelerates the liver damage of Concanavalin A-induced hepatitis.2010
- Author(s)
  Ojiro K, Ebinuma H, Nakamoto N, Wakabayashi K, Mikami Y, Ono Y, Po-Sung C, Usui S, Umeda R, Takaishi H, Yamagishi Y, Saito H, Kanai T, Hibi T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 399 Pages: 744-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] Imbalance of NKp44(+) NKp46(-) and NKp44(-) NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease2010
- Author(s)
  Takayama T, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 139(3) Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset.2010
- Author(s)
  Takada Y, Hisamatsu T, Kamada N, Kitazume MT, Honda H, Oshima Y, Saito R, Takayama T, Kobayashi T, Chinen H, Mikami Y, Kanai T, Okamoto S, Hibi T.
- Journal Title
  
  J Immunol.
  
  Volume: 184 Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] Competitio between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis2010
- Author(s)
  Mikami Y, Kanai T, Hisamatsu T, Hibi T., et al.
- Journal Title
  
  Eur J Immunol
  
  Volume: 40(9) Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 血漿アミノ酸プロファイルを用いたIBDの診断IBD Research先端医学社2010
- Author(s)
  久松理一、日比紀文
- Volume
  12月号vol.4 no.4
- Pages
  38-42
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Novel endoscopic activity index is useful for choosing treatment in severe active ulcerative colitis patients.2010
- Author(s)
  Naganuma M, Ichikawa H, Inoue N, Kobayashi T, Okamoto S, Hisamatsu T, Kanai T, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 45(9)
  
  Pages: 936-43
- NAID
  10027698991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.2010
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Takayama T, Kitazume MT, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis.
  
  Volume: 16(4) Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article]2010
- Author(s)
  久松理一, 日比紀文
- Journal Title
  
  炎症性腸疾患と腸管局所免疫 Annual Review 消化器 8-15(中外医学社)
  
  Pages: 8-15
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease2010
- Author(s)
  Kamada N, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 16(4) Pages: 568-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inone N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: Sep;40(9) Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] 血漿アミノ酸プロファイルを用いたIBDの診断2010
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  IBD Research先端医学社
  
  Volume: 12月号vol.4 no.4 Pages: 38-42
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Competition between colitogenic Th1 and Th17 cells contributes to the amelioration of colitis.2010
- Author(s)
  Mikami Y, Kanai T, Sujino T, Ono Y, Hayashi A, Okazawa A, Kamada N, Matsuoka K, Hisamatsu T, Okamoto S, Takaishi H, Inoue N, Ogata H, Hibi T.
- Journal Title
  
  Eur J Immunol.
  
  Volume: 40 Pages: 2409-2422
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] 特集:生体防御と自然免疫-最近の知見Workshop実臨床のトピックスIBD発症進展における自然免疫の役割2010
- Author(s)
  久松理一、日比紀文
- Journal Title
  
  侵襲と免疫
  
  Volume: Vol.19 No.2 Pages: 39-42
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Imbalance of NKp44 (+)NKp46(-) and NKp44(-)NKp46(+) natural killer cells in the intestinal mucosa of patients with Crohn's disease.2010
- Author(s)
  Takayama T, Kamada N, Chinen H, Okamoto S, Kitazume MT, Chang J, Matuzaki Y, Suzuki S, Sugita A, Koganei K, Hisamatsu T, Kanai T, Hibi T.
- Journal Title
  
  Gastroenterology
  
  Volume: Sep;139(3) Pages: 882-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Partial regression of duodenal lesions of intestinal follicular lymphoma after antibiotic treatment.2010
- Author(s)
  Yaguchi T, Imaeda H, Kizaki M, Hosoe N, Suzuki H, Ogata H, Iwao Y, Kameyama K, Ikeda Y, Hibi T.
- Journal Title
  
  Dig Endosc.
  
  Volume: 22 Pages: 316-318
- NAID
  10028187355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659151
[Journal Article] Monocyte chemoattractant protein-1 contributes to gut homeostasis and intestinal inflammation by composition of IL-10-producing regulatory macrophage subset2010
- Author(s)
  Takada Y, Hisamatsu T, Kanai T, Hibi T., et al.
- Journal Title
  
  J Immunol
  
  Volume: 184(5) Pages: 2671-2676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages2009
- Author(s)
  Andou A, Hisamatsu T, Okamoto S, Chinen H, Kamada N, Kobayashi T, Hashimoto M, Okutsu T, Shimbo K, Takeda T, Matsumoto H, Sato A, Ohtsu H, Suzuki M, Hibi T.
- Journal Title
  
  Gastroenterology 136(2)
  
  Pages: 564-574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Retinoic acid contributes to the induction of IL-12-hypoproducing dendritic cells2009
- Author(s)
  Wada Y, Hisamatsu T, Kamada N, Okamoto S, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. 15(10)
  
  Pages: 1548-1556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article]2009
- Author(s)
  齊藤理子, 久松理一, 日比紀文
- Journal Title
  
  マクロファージからのIL-23産生と大腸炎、共生菌の関与臨床免疫・アレルギー科52巻4号(科学評論社)
  
  Pages: 384-388
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article]2009
- Author(s)
  久松理一, 日比紀文
- Journal Title
  
  腸管マクロファージとIBD IBD Research vol.3 no.3(先端医学者)
  
  Pages: 183-187
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article]2009
- Author(s)
  久松理一, 日比紀文
- Journal Title
  
  ATG16L1とTNFSF15G.I Research vol.17 no.6(先端医学社)
  
  Pages: 548-550
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Human CD14+ macrophages in intestinal lamina propria exhibit potent antigen-presenting ability2009
- Author(s)
  Kamada N, Hisamatsu T, Honda H, Kobayashi T, Chinen H, Kitazume MT, Takayama T, Okamoto S, Koganei K, Sugita A, Kanai T, Hibi T
- Journal Title
  
  J Immunol. 183(3)
  
  Pages: 1724-1731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article]2009
- Author(s)
  久松理一, 日比紀文
- Journal Title
  
  Th-17細胞の機能はどこまで明らかになれたか?IBD Research vol.2 no.4(先端医学社)
  
  Pages: 308-313
- Data Source
  KAKENHI-PROJECT-21249048
[Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells.2008
- Author(s)
  Kamada N, Maeda K, Inoue N, Hisamatsu T, Okamoto S, Hong KS, Yamada T, Watanabe N, Tsuchimoto K, Ogata H, Hibi T
- Journal Title
  
  Infect Immun 76(1)
  
  Pages: 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease2008
- Author(s)
  Takaishi H, Inoue N, Hibi T, et. al.
- Journal Title
  
  Int J Med Microbiol (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Endoscopic and chromoendoscopic atlas featuring dysplastic lesions in surveillance colonoscopy for patients with long-standing ulcerative colitis.2008
- Author(s)
  Matsumoto T, Iwao Y, Igarashi M, Watanabe K, Otsuka K, Watanabe T, Iizuka B, Hida N, Sada M, Chiba T, Kudo SE, Oshitani N, Nagawa H, Ajioka Y, Hibi T
- Journal Title
  
  Inflamm Bowel Dis 14(2)
  
  Pages: 259-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008
- Author(s)
  Kamada, N, Inoue, N, Hibi, T, et. al.
- Journal Title
  
  Infect Immun 76(1)
  
  Pages: 214-220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Lower doses of 6-mercaptopurine/azathioprine bring enough clinical efficacy and therapeutic concentration of erythrocyte 6-mercaptopurine metabolite in Japanese IBD patients.2008
- Author(s)
  Komiyama T, Yajima T, Kubota R, Iwao Y, Sakuraba A, Funakoshi S, Negishi K, Minami I, Tanaka Y, Mae H, Hibi T
- Journal Title
  
  J Crohns Colitis 2(4)
  
  Pages: 315-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590748
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 inhibits signal transd uction in intestinal epithelial cells2008
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Infect Immun 76
  
  Pages: 214-220
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease.2008
- Author(s)
  Takaishi H, Matsuki T, Nakazawa A, Takada T, Kado S, Asahara T, Kamada N, Sakuraba A, Yajima T, Higuchi H, Inoue N, Ogata H, Iwao Y, Nomoto K, Tanaka R, Hibi T
- Journal Title
  
  Int J Med Microbiol 298(5-6)
  
  Pages: 463-472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Imbalance in intesthlal microf[ora constitution could be ivolved in thepathogenesis of inflammatory bowel disease2008
- Author(s)
  Takaishi H, Inoue N, Hibi, T, et. al.
- Journal Title
  
  Int J Med Microbiol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coh strain Nissle 1917 inhibits signal transduction in intestinal epithelial cells2008
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Infect Immun 76
  
  Pages: 214-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice2008
- Author(s)
  Nanno M, Inoue N, Hibi T, et. al.
- Journal Title
  
  Gastroenterology 134
  
  Pages: 481-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Exacerbating role of gammadelta T cells in chronic colitis of T-cell receptor alpha mutant mice.2008
- Author(s)
  Nanno M, Kanari Y, Naito T, Inoue N, Hisamatsu T, Chinen H, Sugimoto K, Shimomura Y, Yamagishi H, Shiohara T, Ueha S, Matsushima K, Suematsu M, Mizoguchi A, Hibi T, Bhan AK, Ishikawa
- Journal Title
  
  Gastroenterology 134(2)
  
  Pages: 481-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20200080
[Journal Article] Exclusive increase of CX3CR1+CD28-CD4+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.2007
- Author(s)
  Kobayashi T, Nakazawa A, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Disease (In press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007
- Author(s)
  Matsuoka K, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol (in press)
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine2007
- Author(s)
  Matsumoto T, Hibi T, Watanabe M et al.
- Journal Title
  
  Gastroenterology 128・7
  
  Pages: 1851-1867
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis2007
- Author(s)
  Yoshizawa S, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Curriculum vitae of intestinal intraepithelial T cells-their developmental and behavioral characteristics.2007
- Author(s)
  Ishikawa H, Hibi T et al.
- Journal Title
  
  Immunol Rev 215・1
  
  Pages: 154-165
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007
- Author(s)
  Ishikawa H, Hibi T et al.
- Journal Title
  
  Immunol Rev 215・1
  
  Pages: 154-165
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007
- Author(s)
  Isliikawa H, Naito T, Iwanaga T, Takahashrlwanaga H, Suematsu M, Hibi T, Nanno M
- Journal Title
  
  Immunol Rev 215 (1)
  
  Pages: 154-165
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007
- Author(s)
  Ishikawa H, Hibi T et al.
- Journal Title
  
  Immunol Rev 215・1
  
  Pages: 154-165
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Clinical significance of serum. p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Matsuoka K, Inoue N, Takaishi H, Ogata H, Iwao Y, Mukai M, Fujita T, Kawakami Y, Hibi H.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Inoue N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Exclusive increase of CX3CR1^+CD28^-CD4^+ T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.2007
- Author(s)
  Kobayashi T, Okamoto S, Iwakami Y, Nakazawa A, Hisamatsu T, Chinen H, Kamada N, Imai T, Goto H, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Curriculum vitae of intestinal intraepithelial T cells : their developmental and behavioral characteristics.2007
- Author(s)
  Ishikawa H, Hibi T et al.
- Journal Title
  
  Immunol. Rev 215・1
  
  Pages: 154-165
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Cytomegalovirus is frequently reactivated and disappears without antiviral agents in ulcerative colitis patients.2007
- Author(s)
  Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajitna T, Hisamatsu T, Okamoto S, Morohoshi Y, Izumiya M, Ichikawa H, Sato T, Inoue N, Ogata H, Hibi T.
- Journal Title
  
  Am J Gastroenterol 102 (2)
  
  Pages: 331-337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007
- Author(s)
  Matsuoka K, Iwao Y, Inoue N, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol (in press)
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2007
- Author(s)
  Matsuoka K, Inoue N, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol (in press)
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Clinical significance of serum p53 antibodies in patients with ulcerative colitis and its carcinogenesis.2007
- Author(s)
  Yoshizawa S, Inoue N, Iwao Y, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Inoue N, Hibi T et al.
- Journal Title
  
  J Gastroenterol 41・4
  
  Pages: 318-324
- NAID
  10018141558
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.2006
- Author(s)
  Ogata H, Hibi T et al.
- Journal Title
  
  Gut 55(9)
  
  Pages: 1255-1262
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Cytomegalovirus Is Frequently Reactivated and Disappears Without Antiviral Agents in Ulcerative Colitis Patients.2006
- Author(s)
  Matsuoka K, Hibi T et al.
- Journal Title
  
  Am J Gastroenterol 102(2)
  
  Pages: 331-337
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Hibi T et al.
- Journal Title
  
  J Gastroenterol 41(4)
  
  Pages: 318-324
- NAID
  10018141558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Matsuoka K, Chinen H, Kamada N, Sato T, Hisamatsu T, Okamoto S, Inoue N, Takaishi H, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 41 (4)
  
  Pages: 318-324
- NAID
  10018141558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Inoue N, Iwao Y, Hibi T et al.
- Journal Title
  
  J Gastroenterol Apr.41(4)
  
  Pages: 318-324
- NAID
  10018141558
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Hibi T et al.
- Journal Title
  
  J Gastroenterol 41・4
  
  Pages: 318-324
- NAID
  10018141558
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis.2006
- Author(s)
  Morohoshi Y, Matsuoka K, Chinen H, Kamada N, Sato T, Hisamatsu T, Okamoto S, Inoue N, Takaishi H, Ogata H, Iwao Y, Hibi T
- Journal Title
  
  J Gastroenterol 41(4)
  
  Pages: 318-24
- NAID
  10018141558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Nonpathogenic Escherichia coil strain Nissle1917 prevents murine acute and chronic colitis2006
- Author(s)
  Kamada N, Inoue N, Hibi T, et. al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Cytomegalovirus is frequently reactivated and disappears without anti-viral agents in ulcerative colitis patients.2006
- Author(s)
  Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajima T, Hisamatsu T, Okamoto S, Morohoshi Y, Izumiya M, Ichikawa H, Sato T, Inoue N, Ogata H, Hibi T
- Journal Title
  
  Am J Gastroenterol 102(2)
  
  Pages: 331-337
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Inhibition of neutrophil elastase prevents the development of murine dextran sulfate sodium-induced colitis2006
- Author(s)
  Morohoshi Y, Hibi T et al.
- Journal Title
  
  J Gastroenterol 41・4
  
  Pages: 318-324
- NAID
  10018141558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] A randomised dose finding study of oral tacrolimus (FK506) therapy in refractory ulcerative colitis.2006
- Author(s)
  Ogata H, Matsui T, Nakamura M, Iida M, Takazoe M, Suzuki Y, Hibi T
- Journal Title
  
  Gut 55(9)
  
  Pages: 1255-1262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Nonpathogenic Escherichia coli strain Nisslel917 prevents murine acute and chronic colitis.2006
- Author(s)
  Kamada N, Inoue N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] The logics of leucocytapheresis as a natural biological therapy for inflammatory bowel disease.2006
- Author(s)
  Kanai T, Hibi T, Watanabe M
- Journal Title
  
  Expert Opin Biol Ther. 6
  
  Pages: 453-466
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390215
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis2006
- Author(s)
  Kamada, N, Inoue, N, Hibi, T, et. al.
- Journal Title
  
  Inflamm Bowel Dis 11(5)
  
  Pages: 455-463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Styrene-Coated Iron Nanobeads for Medical Use2005
- Author(s)
  Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M.
- Journal Title
  
  IEEE Trans.Magn.Soc. 41,10
  
  Pages: 4143-4145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005
- Author(s)
  Sato I, Hibi T, et al.
- Journal Title
  
  GUT (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Thi immune response.2005
- Author(s)
  Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T
- Journal Title
  
  GUT (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Hibi T et al.
- Journal Title
  
  J Gastroenterol Hepatol 20・5
  
  Pages: 710-715
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Inoue N, Hisamatsu T, Kashiwagi K, Takaishi H, Kanai T, Watanabe M, Ishii H, Hibi T.
- Journal Title
  
  J Gastrornt Hepatol 20
  
  Pages: 710-715
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Non-pathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis.2005
- Author(s)
  Kamada N, Jnoue N, Hisamatsu T, Okamoto S, Matsuoka K, Sato T, Chinen H, Hong KS, Yamada T, Suzuki Y, Suzuki T, Watanabe N, Tsuchimoto K, Hibi T
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Abnormally Differentiated Subsets of Intestinal Macrophage Play a Key Role in Th1-Dominant Chronic Colitis through Excess Production of IL-12 and IL-23 in Response to Bacteria.2005
- Author(s)
  Kamada, N., Hisamatsu, T., Okamoto, S., Sato, T., Matsuoka, K., Arai, K., Nakai, T., Hasegawa, A., Inoue, N., Watanabe, N., Akagawa, K., Hibi, T.
- Journal Title
  
  J of Immunol 175・10
  
  Pages: 6900-6908
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005
- Author(s)
  Hibi T, Sakuraba A
- Journal Title
  
  Nat Clin Pract Gastroenterol & Hepatol 2・5
  
  Pages: 200-202
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Nonpathogenic Escherichia coli strain Nissle1917 prevents murine acute and chronic colitis.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11(5)
  
  Pages: 455-463
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Thl-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N., Hisamatsu T., Okamoto S., Sato T., Matsuoka K., Arai K., Nakai T., Hasegawa A., Inoue N., Watanabe N., Akagawa KS., Hibi T.
- Journal Title
  
  J Immunol 175
  
  Pages: 6900-6908
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005
- Author(s)
  Sato T, Nakai T, Tamura N, Okamoto S, Matsuoka K, Sakuraba A, Fukushima T, Uede T, Hibi T
- Journal Title
  
  Gut 54
  
  Pages: 1254-1262
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Hisamatsu T, Okamoto S, Sato T, Matsuoka K, Arai K, Nakai T, Hasegawa A, Inoue N, Watanabe N, Akagawa KS, Hibi T
- Journal Title
  
  J.Immunol 175
  
  Pages: 6900-6908
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005
- Author(s)
  Hitotsumatsu O, Hibi T et al.
- Journal Title
  
  J Gastroenterol 40・10
  
  Pages: 956-963
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  J Immunol 175・10
  
  Pages: 6900-6908
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara, T., Inoue, N., Hisamatsu, T., Kashiwagi, K., Takaishi, H., Kanai, T., Watanabe, M., Ishii, H., Hibi, T.
- Journal Title
  
  J Gastroenterol Hepatol 20・5
  
  Pages: 710-715
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Styrene-Coated Iron Nanobeads for Medical Use.2005
- Author(s)
  Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M
- Journal Title
  
  IEEE Trans.Magn.Soc. 41
  
  Pages: 4143-4145
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Data Source
  KAKENHI-PROJECT-17659221
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005
- Author(s)
  Sato T, Nakai T, Tamura N, Okamoto S., Matsuoka K, Sakuraba A., Fukushima T, Uede T., Hibi T
- Journal Title
  
  Gut 54
  
  Pages: 1254-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005
- Author(s)
  Matsumoto T, Hibi T, Watanabe M et al.
- Journal Title
  
  Gastroenterology 128・7
  
  Pages: 1851-1867
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Nonpathogenic Escherichia coli Strain Nissle 1917 Prevents Murine Acute and Chronic Colitis.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Preparlation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening2005
- Author(s)
  Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
- Journal Title
  
  JOURNAL OF APPLIED PHYSICS 97
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and hronic colitis.2005
- Author(s)
  da, N., Inoue, N., Hisamatsu, T., oto, S., Matsuoka, K., Sato, T., en, H., Su Hong K., Yamada, T., ki, Y., Suzuki, T., Watanabe, N., himoto, K., Hibi, T.
- Journal Title
  
  Inflamm Bowel Dis 11・5
  
  Pages: 455-463
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Preparation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening.2005
- Author(s)
  Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
- Journal Title
  
  JOURNAL OF APPLIED PHYSICS 97
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005
- Author(s)
  Hitotsumatsu O, Inoue N, Hibi T, Ishikawa H et al.
- Journal Title
  
  J Gastroenterol 40・10
  
  Pages: 956-963
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Preparlation of medical magnetic nanobeads with ferrite particles encapsulated in a polyglycidyl methacrylate (GMA) for bioscreening2005
- Author(s)
  Nishibiraki, H., Kuroda, C.S., Maeda, M., Matsushita, N., Abe, M., Handa, H.
- Journal Title
  
  JOURNAL OF APPLIED PHYSICS 97,10Q919
  
  Pages: 1-3
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] IL-7 exacerbates chronic colitis with expansion of memory IL-7R^<high>CD4^+ mucosal T cells in mice.2005
- Author(s)
  Okada E, Yamazaki M, Tanabe M, Takeuchi T, Nanno M, Oshima S, Okamoto R, Tsuchiya K, Nakamura T, Kanai T, Hibi T, Watanabe M.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 288
  
  Pages: 745-754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Leudocytapheresis in ulcerative colitis : results of a multicenter double-blind prospective case-control study pith sham apheresis as placebo treatment.2005
- Author(s)
  Sawada, k., Kusugami, K., Suzuki, Y., Bamba, T., Munakata, A., Hibi, T., Shimoyama, T.
- Journal Title
  
  Am J Gastroenterol 100・6
  
  Pages: 1362-1369
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005
- Author(s)
  Matsumoto T, Okamoto R, Yajima T, Mon T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
- Journal Title
  
  Gastroenterology 128(7)
  
  Pages: 1851-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590674
[Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005
- Author(s)
  Hitotsumatsu O, Hibi T et al.
- Journal Title
  
  J Gastroenterol 40・10
  
  Pages: 956-963
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005
- Author(s)
  Hibi, T., Sakuraba, A
- Journal Title
  
  Nat Clin Pract Gastroenterol & Hepatol 2・5
  
  Pages: 200-202
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Identification and characterization of novel gut-associated lymphoid tissues in rat small intestine.2005
- Author(s)
  Hitotsumatsu, O., Hamada, H., Naganuma, M., Inoue, N., Ishii, H., Hibi, T., Ishikawa, H.
- Journal Title
  
  J Gastroenterol 40・10
  
  Pages: 956-963
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Nonpathogenic Escherichia coli strain Nissle 1917 prevents murine acute and chronic colitis.2005
- Author(s)
  Kamada N, Inoue N, Hisamatsu T, Okamoto S, Matsuoka K, Sato T, Chinen H, Su Hong K, Yamada T, Suzuki Y, Suzuki T, Watanabe N, Tsuchimoto K, Hibi T.
- Journal Title
  
  Inflamm Bowel Dis 11 (5)
  
  Pages: 455-463
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  J Immunol 175(10)
  
  Pages: 6900-6908
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005
- Author(s)
  Sato T, Hibi T et al.
- Journal Title
  
  Gut 54(9)
  
  Pages: 1254-1262
- Data Source
  KAKENHI-PROJECT-17590676
[Journal Article] Styrene-Coated Iron Nanobeads for Medical Use2005
- Author(s)
  Kuroda, C.S., Maeda, M., Nishibiraki, H., Matsushita, N., Handa, H., Abe, M.
- Journal Title
  
  IEEE Trans. Magn. Soc. 41, 10
  
  Pages: 4143-4145
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Hibi T et al.
- Journal Title
  
  J Immunol 175・10
  
  Pages: 6900-6908
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Therapeutic efficacy of infliximab on active Crohn's disease under nutritional therapy.2005
- Author(s)
  Matsumoto, T., Iida, M., Kohgo, Y., Imamura, A, Kusugami, K., Nakano, H., Fujiyama, Y., Matsui, T., Hibi, T.
- Journal Title
  
  Scand J Gastroenterol 40・12
  
  Pages: 1423-1430
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Is there a role for apheresis in gastrointestinal disorders?2005
- Author(s)
  Hibi T, Sakuraba A
- Journal Title
  
  Nat Clin Pract Gastroenterol & Hepatol 2・5
  
  Pages: 200-202
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria.2005
- Author(s)
  Kamada N, Inoue N, Hibi T et al.
- Journal Title
  
  J Immunol 175・10
  
  Pages: 6900-6908
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.2005
- Author(s)
  Matsumoto T, Okamoto R, Yajima T, Mori T, Okamoto S, Ikeda Y, Mukai M, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
- Journal Title
  
  Gastroenterology 127 (7)
  
  Pages: 1851-1867
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209024
[Journal Article] Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response.2005
- Author(s)
  Sato T, Hibi T, et al.
- Journal Title
  
  GUT (in press)
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Clinical significance of microsatellite instability in the inflamed mucosa for the prediction of colonic neoplasms in patients with ulcerative colitis.2005
- Author(s)
  Tahara T, Inoue N, Hibi T et al.
- Journal Title
  
  J Gastroenterol Hepatol 20・5
  
  Pages: 710-715
- Data Source
  KAKENHI-PROJECT-17590677
[Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004
- Author(s)
  Okazawa A, Kanai T, Nakamaru K, Sato T, Inoue N, Ogata H, Jwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto R, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T
- Journal Title
  
  Clin Exp Immunol 136(2)
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Human intestinal epithelia-derived IL-18 is a potent prolifrerative factor for intraepithelial lymphocytes synergistically with IL-2, IL-7 and IL-15.2004
- Author(s)
  Okazawa A, Kanai T, Nakamaru T, Sato T, Inoue N, Ogata H, Iwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto R, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T.
- Journal Title
  
  Clin Exp Immunol 136
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammtory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004
- Author(s)
  Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T
- Journal Title
  
  Cancer Res. 64(22)
  
  Pages: 8239-8248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Croha's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Gut 53(9)
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Atsushi Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T.
- Journal Title
  
  Gut 53
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hepatitis C virus infection in human liver tissue engrafted in mice with an infectious molecular clone.2004
- Author(s)
  Maeda N, Watanabe M, Okamoto S, Kanai T, Yamada T, Hata J, Hozumi N, Katsume A, Nuriya H, Sandhu J, Ishii H, Kohara M, Hibi T.
- Journal Title
  
  Liver Int 24
  
  Pages: 259-267
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Gut 53(9)
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Hibi T, et al.
- Journal Title
  
  GUT 53・9
  
  Pages: 1303-1308
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Gut 53
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Hyperexpression of inducible costimulator its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Hibi T, et al.
- Journal Title
  
  Gastroenterology 126・3
  
  Pages: 829-839
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto 5, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kxoczek RA, Fukushima T, Ishii H, Hibi T
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004
- Author(s)
  Okazawa A, Hibi T, et al.
- Journal Title
  
  Cin Exp Immunol 136・2
  
  Pages: 269-276
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Kanai T, Watanabe M, Sakuraba A, Okamoto S, Nakai T, Okazawa A, Inoue N, Totsuka T, Yamazaki M, Kroczek RA, Fukushima T, Ishii H, Hibi T
- Journal Title
  
  Gastroenterology 126(3)
  
  Pages: 829-839
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease.2004
- Author(s)
  Matsuoka K, Hibi T, et al.
- Journal Title
  
  GUT 53
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Limited capability of regional lymph nodes to eradicate metastatic cancer cells.2004
- Author(s)
  Nagata H, Arai T, Soejima Y, Suzuki H, Ishii H, Hibi T
- Journal Title
  
  Cancer Res 64(22)
  
  Pages: 8239-8248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Hyperexpression of inducible costimulator and its contribution on lamina propria T cells in inflammatory bowel disease.2004
- Author(s)
  Sato T, Hibi T, et al.
- Journal Title
  
  Gastroenterology 126
  
  Pages: 829-839
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Human intestinal epithelial cell-derived interleukin (IL)-18, along with IL-2, IL-7 and IL-15, a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004
- Author(s)
  Okazawa A, Hibi T, et al.
- Journal Title
  
  Clin Exp Immunol 136
  
  Pages: 269-276
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2004
- Author(s)
  Ezaki T, Watanabe M, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
- Journal Title
  
  Cancer Res. 63
  
  Pages: 3747-3749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal canders.2004
- Author(s)
  Ezaki T, Watanabe M, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
- Journal Title
  
  Cancer Res 63
  
  Pages: 3747-3749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] T-bet up-regulation and subsequent interleukin 12 stimulation are essential for the induction of Th1 mediated immunopathology in Crohn's disease2004
- Author(s)
  Matsuoka K, Inoue N, Sato T, Okamoto S, Hisamatsu T, Kishi Y, Sakuraba A, Hitotsumatsu O, Fukushima T, Kanai T, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Gut 53
  
  Pages: 1303-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209019
[Journal Article] Human intestinal epithelial cell-derived interleukin(IL)-18, along with IL-2, IL-7 and IL-15, is a potent synergistic factor for the proliferation of intraepithelial lymphocytes.2004
- Author(s)
  Okazawa A, Kanai T, Nakamaru K, Sato T, Jnoue N, Ogata H, Iwao Y, Ikeda M, Kawamura T, Makita S, Uraushihara K, Okamoto H, Yamazaki M, Kurimoto M, Ishii H, Watanabe M, Hibi T
- Journal Title
  
  Clin Exp Immunol 136(2)
  
  Pages: 269-276
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Granulocytapheresis is useful as an alterative therapy in patients with steroid-refractory or -dependent ulcerative colitis.2004
- Author(s)
  Naganuma M, Funakoshi S, Sakuraba A, Takagi H, Inoue N, Ogata H, Iwao Y, Ishii H, Hibi T
- Journal Title
  
  Inflamm Bowel Dis 10(3)
  
  Pages: 251-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Mucosal T cells expressing high levels of IL-7 receptor are potential targets for treatment of chronic colitis.2003
- Author(s)
  Yamazaki M, Yajima T, Tanabe M, Fukui K, Okada E, Okamoto R, Oshima S, Nakamura T, Kanai T, Takeuchi T, Uehira M, Ishikawa H, Hibi T, Watanabe M.
- Journal Title
  
  J Immunol 171
  
  Pages: 1556-1563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate (DSS) colitis in mice.2003
- Author(s)
  Takagi H, Kanai T, Okazawa A, Kishi Y, Sato T, Takaishi H, Inoue N, Ogata H, Iwao Y, Hoshino K, Takeda K, Akira S, Ishii H, Watanabe M, Hibi T.
- Journal Title
  
  Scan J Gastroenterol 33
  
  Pages: 837-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulphate colitis in mice.2003
- Author(s)
  Takagi H, Hibi T, et al.
- Journal Title
  
  Scand J Gastroenterol 38
  
  Pages: 837-844
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003
- Author(s)
  Ezaki, Watanabe M, Inoue N, Kanai T^#, Ogata H, Iwao Y, Ishii H, Hibi T.
- Journal Title
  
  Cancer Res 63
  
  Pages: 3747-3749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Contrasting action of IL-12 and IL-15 in the development of dextran sodium sulfate colitis in mice.2003
- Author(s)
  Takagi T, Kanai T, Okazawa A, Sato T, Takaishi H, Inoue N, Ogata H, Hoshino K, Takeda K, Akira S, Watanabe M, Jshii H, Hibi T
- Journal Title
  
  Scand J Gastroenterol 38(8)
  
  Pages: 837-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590685
[Journal Article] Ameliorating effect of anti-ICOS monoclonal antibody in a murine model of chronic colitis.2003
- Author(s)
  Totsuka T, Kanai T^#, Iiyama R, Uraushihara K, Yamazaki M, Okamoto R, Hibi T, Tezuka K, Azuma M, Akiba H, Yagita H, Okumura K, Watanabe M.
- Journal Title
  
  Gastroenterology 124
  
  Pages: 410-421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] IL-18 overexpression exacerbates the development of colitis with marked infiltrates macrophages in IL-18 transgenic mice.2003
- Author(s)
  Ishikura T, Kanai T^#, Uraushihara K, Iiyama R, Makita S, Totsuka T, Yamazaki M, Sawada T, Nakamura T, Kitahora T, Hibi T, Hoshino T, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol 18
  
  Pages: 960-969
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Hyperexpression of inducible costimulator (ICOS) on lamina propria mononuclear cells in rat dextran sulfate sodium (DSS).2003
- Author(s)
  Ishii K, Kanai T, Ishikura T, Totsuka T, Uraushihara K, Yamazaki M, Okamoto R, Araki A, Ohka S, Miyata T, Nakamura T, Kitahora T, Hibi T, Tezuka K, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol 19
  
  Pages: 174-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] A specific genetic alteration on chromosome 6 in ulcerative colitis-associated colorectal cancers.2003
- Author(s)
  Ezaki T, Watanabe M, Inoue N, Kanai T, Ogata H, Iwao Y, Ishii H, Hibi T
- Journal Title
  
  Cancer Res 63(13)
  
  Pages: 3747-3749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Contrasting action of IL-12 and IL-18 in the development of dextran sodium sulfate colitis in mice.2003
- Author(s)
  Takagi T, Kanai T, Okazawa A, Sato T, Takaishi H, Inoue N, Ogata H, Hoshino K, Takeda K, Akira S, Watanabe M, Ishii H, Hibi T
- Journal Title
  
  Scand J Gastroenterol 38(8)
  
  Pages: 837-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590684
[Journal Article] Damaged epithella regenerated by bone marrow-derived cells in the human gastrointestinal tract.2002
- Author(s)
  Okamoto, R., Yajima, T., Yamazalci, M., Kanai, T., Mukai, M., Okamoto, S., Ikeda, Y., Hibi, T., Inazawa, J., Watanabe, M.
- Journal Title
  
  Nature Medicine 8
  
  Pages: 1011-1017
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13GS0015
[Journal Article] TGR5 signaling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease
- Author(s)
  Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, KoganeiK, Sugita A, Kanai T, Hibi T
- Journal Title
  
  Immunology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Activated Hepatic Stellate Cells Mediate the Differentiation of Macrophages.
- Author(s)
  Chang J, Hisamatsu T, Shimamura K, Yoneno K, Adachi M, Naruse H, Igarashi T, Higuchi H, Matsuoka K, Kitazume MT, Ando S, Kamada N, Kanai T, and Hibi T
- Journal Title
  
  Hepatology Research
  
  Volume: (in press)
- NAID
  10031194568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Inducible colitis-associated glycome capable of stimulating the proliferation of memory CD4+ T cells
- Author(s)
  Nishida A, Nagahama K, Imaeda H, Ogawa A, Lau CW, Kobayashi T, Hisamatsu T, Preffer FI, Mizoguchi E, Ikeuchi H, Hibi T, Fukuda M, Andoh A, Blumberg RS, Mizoguchi A
- Journal Title
  
  J Exp Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Journal Article] Increase of bone marrow-derived secretory lineage epithelial cells during regeneration in the human intestine.
- Author(s)
  Matsumoto T, Okamoto R, Yagima T, Mori T, Okamoto S, Ikeda Y, Yamazaki M, Oshima S, Tsuchiya K, Nakamura T, Kanai T, Okano H, Inazawa J, Hibi T, Watanabe M.
- Journal Title
  
  Gastroenterology (in the press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590627
[Journal Article] Anticoagulation therapy dramatically improved severe sigmoiditis with findings resembling inflammatory bowel disease, which was caused by mesenteric venous thrombosis
- Author(s)
  Mikami Y, Kanai T, Iwasaki E, Naganuma M, Yamagishi Y, Shimoda M, Matsuoka K, Hisamatsu T, Iwao Y, Ogata H, Nakatsuka S, Mukai M, Hibi T
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659374
[Presentation] 教育講演「難病克服に向けた新しい消化管再生医療」2015
- Author(s)
  日比紀文
- Organizer
  第11回日本消化管学会総会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 潰瘍性大腸炎患者に対する大腸カプセル内視鏡前処置の工夫（クエン酸モサプリドの効果）2015
- Author(s)
  細江直樹、宮永亮一、三枝慶一郎、小林拓、中野雅、長沼誠、日比紀文、金井隆典、緒方晴彦
- Organizer
  第8回日本カプセル内視鏡学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-15
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 当院における炎症性腸疾患に対するチオプリン製剤使用の実態2015
- Author(s)
  梅田智子、小林拓、中野雅、常松令、芹澤宏、渡辺憲明、日比紀文
- Organizer
  第11回日本消化管学会総会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-14
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 潰瘍性大腸炎粘膜治癒評価における便中S100A12の有用性2015
- Author(s)
  小林拓、中野雅、梅田智子、芹澤宏、渡辺憲明、黒沼智、竹内修、日比紀文
- Organizer
  第11回日本消化管学会総会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 大腸カプセル内視鏡使用経験に関する国内アンケート調査の結果報告-日本カプセル内視鏡学会保健委員会より2015
- Author(s)
  樋口和秀、日比紀文、藤山佳秀、松井敏幸、伊藤文生
- Organizer
  第8回日本カプセル内視鏡学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-02-15
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 広汎な小腸病変を来した潰瘍性大腸炎の一例2014
- Author(s)
  森川淳、小林拓、筋野智久、中野雅、加藤裕佳子、梅田智子、芹澤宏、日比紀文
- Organizer
  日本消化器病学会　関東支部第331回例会
- Place of Presentation
  東京
- Year and Date
  2014-09-20
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 難治性潰瘍性大腸炎治療におけるタクロリムスの位置づけと適正使用法2014
- Author(s)
  日比紀文
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-23
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 潰瘍性大腸炎患者に対するクエン酸モサプリドを用いた大腸カプセル内視鏡前処置法2014
- Author(s)
  細江直樹、中野雅、南木康作、三枝慶一郎、碓井真吾、筋野智久、小林拓、松岡克善、長沼誠、久松理一、井上詠、芹澤宏、日比紀文、金井隆典、緒方晴彦
- Organizer
  第32回　日本大腸検査学会総会
- Place of Presentation
  東京
- Year and Date
  2014-09-06
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 本邦から発信する最適なＵＣ治療戦略2014
- Author(s)
  日比紀文
- Organizer
  第1回　Ｂiologics Workshop on IBD
- Place of Presentation
  東京
- Year and Date
  2014-04-26
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 法制化される新たな難病対策における専門医の役割について2014
- Author(s)
  日比紀文
- Organizer
  第100回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] HUMIRAによる患者参加型治療の実践：生物学的製剤投与法選択のポイント2014
- Author(s)
  日比紀文
- Organizer
  HUMIRA IBD Forum
- Place of Presentation
  東京
- Year and Date
  2014-05-10
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Current and future treatments of IBD in Japan.Are they different from Westerns?2014
- Author(s)
  Toshifumi Hibi
- Organizer
  2014 PUMCH International Digestive Disease Forum
- Place of Presentation
  北京（中国）
- Year and Date
  2014-04-19
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患に対する抗体療法2013
- Author(s)
  日比紀文
- Organizer
  第107回日本内科学会総会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] The future perspective and issues of IBD in Asia2013
- Author(s)
  Toshifumi hibi
- Organizer
  1th AOCC
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患の専門医を目指す若手医師へのメッセージ2013
- Author(s)
  日比紀文
- Organizer
  第11回ＩＢＤセミナー
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Collaboration between the East Asia IBD Society and ECCO2012
- Author(s)
  Toshifumi Hibi
- Organizer
  ECCO Meeting
- Place of Presentation
  Barcelona Spain(招待講演)
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Early normalization of C-reactive protein (CRP)by infliximab is a predictive factor of sustained longterm clinical efficacy in crohn's disease.2012
- Author(s)
  Kimura K, Matsuoka K, Kanai T, Okamoto S,Hisamatsu T, Inoue N, Yajima T, Ogata H, I wa o Y, Hibi T
- Organizer
  The 14th Meeting of International Conference on Ulcer Research
- Place of Presentation
  Tokyo
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-24659374
[Presentation] Collaboration between the East Asia IBD Society and ECCO2012
- Author(s)
  Toshifumi Hibi
- Organizer
  ECCO Meeting
- Place of Presentation
  Spain
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Role of Endoscopy in daily clinical practice : example from Japan2012
- Author(s)
  Toshifumi Hibi
- Organizer
  Leading Change in IBD Meeting
- Place of Presentation
  Prague
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Role of Endoscopy in daily clinical practice : example from Japan2012
- Author(s)
  Toshifumi Hibi
- Organizer
  Leading Change in IBD Meeting
- Place of Presentation
  Prague Ceska Republika(招待講演)
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Early normalization of C-reactive protein (CRP)by infliximab is a predictive factor of sustained long-term clinical efficacy in crohn’s disease.2012
- Author(s)
  26. Kimura K, Matsuoka K, Kanai T, Okamoto S, Hisamatsu T, Inoue N, Yajima T, Ogata H, Iwao Y, Hibi T
- Organizer
  The 14th Meeting of International Conference on Ulcer Research.
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24659374
[Presentation] How to avoid malpractice and deal with difficult IBD cases2011
- Author(s)
  Toshifumi Hibi
- Organizer
  IBD Update II
- Place of Presentation
  台北台湾(招待講演)
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] How to avoid malpractice and deal with difficult IBD cases2011
- Author(s)
  Toshifumi Hibi
- Organizer
  IBD Update
- Place of Presentation
  台湾
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 潰瘍性大腸炎治療の新展開2010
- Author(s)
  日比紀文
- Organizer
  第89回日本消化器内視鏡学会九州支部例会支部例会ランチョンセミナー
- Place of Presentation
  九州
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Japanese Patients With Moderately to Severely Active Crohn's Disease Experience Improved Quality of Life With Adalimumab Treatment2010
- Author(s)
  日比紀文
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] 炎症性腸疾患をアミノ酸代謝から考える2010
- Author(s)
  久松理一、日比紀文
- Organizer
  第8回日本機能性食品医用学会総会シンポジウムI免疫と機能性食品
- Place of Presentation
  大津ピアザ淡海
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] クローン病の病態解明と治療開発2010
- Author(s)
  日比紀文
- Organizer
  第6回日本消化管学会総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2010-02-20
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 血漿アミノ酸プロファイルを用いた炎症性腸疾患の診断・活動性モニタリング2010
- Author(s)
  久松理一、井上詠、松岡克善、斉藤理子、筋野智久、米野和明、三好潤、三上洋平、岩男泰、緒方晴彦、金井隆典、日比紀文、安藤朗、藤山佳秀、内山和彦、高木智久、内藤裕二、吉川敏一
- Organizer
  難治性腸管障害調査研究班
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] 大腸腫瘍性病変に対するESDの工夫2010
- Author(s)
  今枝博之、細江直樹、中溝裕雅、別所理恵子、齋藤理子、小池祐司、井上詠、石井良幸、長谷川博俊、岩男泰、緒方晴彦、北川雄光、日比紀文
- Organizer
  第79回日本消化器内視鏡学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-15
- Data Source
  KAKENHI-PROJECT-20590748
[Presentation] Current Therapy of IBD-Current Concepts2010
- Author(s)
  日比紀文
- Organizer
  IBD Symposium in Taipei
- Place of Presentation
  台湾
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 炎症性腸疾患に対する抗体療法2010
- Author(s)
  日比紀文
- Organizer
  第107回日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-11
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] 腸管マクロファージからみたクローン病のサイトカインネットワーク異常2010
- Author(s)
  久松理一、鎌田信彦、高山哲朗、齋藤理子、米野和明、松岡克善、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
- Organizer
  第47回日本消化器免疫学会総会、シンポジウム
- Place of Presentation
  滋賀
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] 潰瘍性大腸炎治療の新展開2010
- Author(s)
  日比紀文
- Organizer
  第89回日本消化器内視鏡学会九州支部例会支部例会ランチョンセミナー
- Place of Presentation
  福岡
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] Japanese Patients With Moderately to Severely Active Crohn'sDisease Experience Improved Quality of Life With Adalimumab Treatment2010
- Author(s)
  日比紀文
- Organizer
  Digestive Disease Week 2010
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 血漿アミノ酸プロファイルを用いた炎症性腸疾患の診断・活動性モニタリング2010
- Author(s)
  久松理一、井上詠、松岡克善、斉藤理子、筋野智久、米野和明、三好潤、三上洋平、岩男泰、緒方晴彦、金井隆典、日比紀文、安藤朗、藤山佳秀、内山和彦、高木智久、内藤裕二、吉川敏一
- Organizer
  難治性腸管障害調査研究班
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Immunomodulation therapy for IBD2010
- Author(s)
  日比紀文
- Organizer
  2010 Immune-Mediated Digestive Diseases Forum in China
- Place of Presentation
  北京
- Year and Date
  2010-06-13
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] 炎症性腸疾患をアミノ酸代謝から考える2010
- Author(s)
  久松理一、日比紀文
- Organizer
  第8回日本機能性食品医用学会総会シンポジウムI免疫と機能性食品
- Place of Presentation
  大津ピアザ淡海
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Current Therapy of IBD-Current Concepts2010
- Author(s)
  日比紀文
- Organizer
  IBD Symposium in Taipei
- Place of Presentation
  台湾
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-22659151
[Presentation] 日比紀文Current Therapy of IBDCurrent Concepts2010
- Author(s)
  日比紀文
- Organizer
  IBD Symposium
- Place of Presentation
  Taipei台湾
- Year and Date
  2010-08-21
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] Immunomodulation therapy for IBD2010
- Author(s)
  日比紀文
- Organizer
  2010 Immune-Mediated Digestive Diseases Forum in China
- Place of Presentation
  北京
- Year and Date
  2010-06-13
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 炎症性腸疾患に対する抗体療法2010
- Author(s)
  日比紀文
- Organizer
  第107回日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-11
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 胆汁酸はTGR5受容体を介してIL-12低産生型樹状細胞に分化誘導する/Bile acids generate IL-12 hypoproducingDCs via Tgr5 signaling pathway2009
- Author(s)
  Saito R, Hisamatsu T, Takayama T, Kamada N, Ando S, Inoue N, Okamoto S, Kanai T, Hibi T
- Organizer
  第39回日本免疫学会総会・学術集会、ワークショップ
- Place of Presentation
  大阪
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] 炎症性腸疾患診療の新時代2009
- Author(s)
  日比紀文
- Organizer
  第64回日本大腸肛門病学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] 早期大腸癌の内視鏡摘除後における大腸内視鏡サーベイランスの検討2009
- Author(s)
  井田陽介、今枝博之、細江直樹、中溝裕雅、別所理恵子、斉藤理子、小池祐司、井上詠、長谷川博俊、岩男泰、緒方晴彦、杉野吉則、北川雄光、日比紀文
- Organizer
  第27回日本大腸検査学会総会
- Place of Presentation
  東京
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-20590748
[Presentation] 各種 Modality を用いたIBD診療の最前線2009
- Author(s)
  日比紀文
- Organizer
  第27回日本大腸検査学会
- Place of Presentation
  ベルサール九段
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-21249048
[Presentation] IL-10KOマウスにおけるマクロファージからのIL-12過剰産生機序の解明2009
- Author(s)
  成瀬浩史、久松理一、鎌田信彦、岡本晋、井上詠、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会、一般演題
- Place of Presentation
  愛媛
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病におけるCD14+腸管マクロファージの抗原提示能について2009
- Author(s)
  久松理一、鎌田信彦、本田治樹、北爪美奈、井上詠、岡本晋、金井隆典、日比紀文
- Organizer
  第46回日本消化器免疫学会、シンポジウム
- Place of Presentation
  愛媛
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] MCP-1依存性腸管マクロファージサブセットの腸管免疫恒常性における役割2008
- Author(s)
  高田康裕、久松理一、鎌田信彦、斎藤理子、高山哲朗、市川仁志、小林拓、知念寛、井上詠、岡本晋、日比紀文
- Organizer
  第45回日本消化器免疫学会、一般演題
- Place of Presentation
  京都
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] クローン病における腸管マクロファージの腸内細菌認識異常 -IL-23を中心とした慢性炎症サイクル-2008
- Author(s)
  久松理一、鎌田信彦、小林拓、岡本晋、井上詠、緒方晴彦、金井隆典、日比紀文
- Organizer
  第45回日本消化器免疫学会、シンポジウム
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20200080
[Presentation] Mucosal CD4+T cells with high CD26 surface expression are enrichedfor memory Th1 cells and involved in the pathogenesis of inflammatorybowel disease2007
- Author(s)
  Inoue N, Hibi T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-29
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] Mucosal CD4+ T cells with high CD26 surface expression are enriched for memory Thl cells and involved in the pathogenesis of inflammatory bowel disease2007
- Author(s)
  Inoue N, Hibi T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris,France
- Year and Date
  2007-10-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] Mucosal CD^<4+>T cells with high CD26 surface expression are enriched for memory Th1 cells and involved in the pathogenesis of inflammatory bowel disease2007
- Author(s)
  Inoue, N, Hibi, T, et. al.
- Organizer
  15th United Gastroenterology Week
- Place of Presentation
  Paris, France
- Year and Date
  2007-10-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590677
[Presentation] 炎症性腸疾患診療における内視鏡検査の意義
- Author(s)
  日比紀文
- Organizer
  第97回日本消化器内視鏡学会関東地方会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] クローン・潰瘍性大腸炎の先進治療に向けて
- Author(s)
  日比紀文
- Organizer
  第30回わかば会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] ＩＢＤ領域における治療の現況と展望
- Author(s)
  日比紀文
- Organizer
  日本化薬社内勉強会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 土屋先生の想い出と消化器免疫への提言
- Author(s)
  日比紀文
- Organizer
  第50回日本消化器免疫学会イブニングセミナー
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 腹部症状から診たIBDと他疾患の特徴と内視鏡診断
- Author(s)
  日比紀文
- Organizer
  IBD Clinical Conference
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患診療のパラダイムシフト～カプセル内視鏡の臨床応用と生物学的製剤について～
- Author(s)
  日比紀文
- Organizer
  目黒区医師会内科部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患の病態解明と治療の進歩
- Author(s)
  日比紀文
- Organizer
  第110回日本内科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Impact of Inflammatory Bowel Disease on Japanese patients` lives : International comparison of patients` views
- Author(s)
  F.Ueno,Y.Nakayama,E.Hagiwara,O.Mikami,A.Inamine-Sasaki,T.Hibi
- Organizer
  10th Congress of ECCO
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-02-18 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 「総合診療医」とは？-日本での取り組みと消化器分野での診療の実際-炎症性腸疾患診療でのParadigm Shift
- Author(s)
  日比紀文
- Organizer
  中日国際消化疾病論壇
- Place of Presentation
  北京（中国）
- Year and Date
  2014-08-31 – 2014-09-01
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Efficacy, Safety, and Demographics Factor of Adalimumab Therapy in 1693 Japanese Crohn's Disease Patients
- Author(s)
  Haruhiko Ogata, Mamoru Watanabe, Toshiyuki Matsui, Sadanori Abe, Shigenori Haruna, Toshifumi Hibi
- Organizer
  DDW
- Place of Presentation
  神戸
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患診療のパラダイムシフト～カプセル内視鏡の臨床応用と生物学的製剤について～
- Author(s)
  日比紀文
- Organizer
  東京消化管フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 遠位回腸検索における受動湾曲高伝達挿入部搭載細径大腸内視鏡ＰＣＦ-ＰＱ260Ｌの有用性の検討
- Author(s)
  中野雅、小林拓、筋野智久、加藤裕佳子、芹澤宏、渡辺憲明、日比紀文、中里圭宏
- Organizer
  第87回　日本消化器内視鏡学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 下痢・下血を来す疾患の診断から治療まで～その現状と新展開～
- Author(s)
  日比紀文
- Organizer
  港区内科医会学術講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Amino acids and inflammatory bowel disease-as a therapeutic target and a novel biomarker
- Author(s)
  Toshifumi hibi
- Organizer
  8th Asia Pacific Conference
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Percutaneous Endoscopic Gastrostomy Under Steady Pressure Automatically Controlled Endoscopy (SPACE)
- Author(s)
  Hiroyuki Imaeda, Kiyokazu Nakajima, Naoki Hosoe, Masanori Nakahara, Shinichiro Zushi, Motohiko Kato, Kazuhiro Kashiwagi, Yasushi Matsumoto, Rieko Nakamura, Noihiro Wada, Masahiko Tsujii, Naohisa Yahagi, Toshifumi Hibi, Tetsuo Takahara.
- Organizer
  DDW
- Place of Presentation
  神戸
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Diffrences between treatment guidelines in IBD
- Author(s)
  Toshifumi hibi
- Organizer
  Falk Symposium 188
- Place of Presentation
  Stuttgart,Germany
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患診療の黎明期・確立期と今後の展開
- Author(s)
  日比紀文
- Organizer
  第10回千葉ＩＢＤアフェレーシス研究会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 潰瘍性大腸炎の治療－基本から応用まで
- Author(s)
  日比紀文
- Organizer
  日本大腸肛門病学会第22回教育セミナー講演
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] クローン病狭窄病変に対する内視鏡的バルーン拡張術の短期・長期成績
- Author(s)
  小林拓、長沼誠、久松理一、松岡克善、中野雅、緒方晴彦、日比紀文、金井隆典
- Organizer
  第87回　日本消化器内視鏡学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 大きく変化した炎症性腸疾患の診療～その適切な対応は？～
- Author(s)
  日比紀文
- Organizer
  消化器疾患セミナー
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Infliximab therapy for Japanese patients with Ulcerative Colitis : Efficacy,safety,and association between serum infliximab levels and early respnse in a randomized, double-blind,placebo-controlled study
- Author(s)
  Y.Suzuki,S.Motoya,F.Hirai,H.Ogata,H.Ito,N.Sato,K.Ozaki,M.Watanabe,T.Hibi
- Organizer
  10th Congress of ECCO
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-02-18 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患診療のパラダイムシフト
- Author(s)
  日比紀文
- Organizer
  第8回名古屋市大消化器・代謝内科フォーラム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 炎症性腸疾患に対する治療の進歩と“粘膜治癒”の意義
- Author(s)
  日比紀文
- Organizer
  第85回日本消化器内視鏡学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Twice-daily budesonide rectal foam induces complete mucosal healing in Japanese patients with mild to moderate Ulcerative Colitis : Results of multicentre, randomised, double-blind,placebo-controlled trial
- Author(s)
  N.Aoyama,Y.Suzuki,H.Nishino,K.Kobayashi,F.Hirai,K.Watanabe,M,Naganuma,T.Hibi
- Organizer
  10th Congress of ECCO
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-02-18 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 日本における炎症性腸疾患薬物療法の現状と新たな治療薬への期待
- Author(s)
  日比紀文
- Organizer
  ＰＭＤＡワークショップ
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 日本の炎症性腸疾患研究の歴史と将来への提言
- Author(s)
  日比紀文
- Organizer
  第68回大腸肛門病学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] Usefulness of faecal S100A12 in defining mucosal healing in Ulcerative Colitis
- Author(s)
  T.Kobayashi, O.Takeuchi,S.Kuronuma,M.nakano,S.Umeda,H.Serizawa,N.Watanabe,T.Hibi.
- Organizer
  10th Congress of ECCO
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2015-02-18 – 2015-02-21
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 生物学製剤全盛時にＧＭＡの位置付けを問う
- Author(s)
  日比紀文
- Organizer
  第21回ＪＤＤＷ
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] AJM300, an Oral α4 Integrin Antagonist, for Active Ulcerative Colitis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2A Study
- Author(s)
  Mamoru Watanabe, Naoki Yoshimura, Satoshi Motoya, Keiichi Tominaga, Ryuichi Iwakiri, Kenji Watanabe, Toshifumi Hibi
- Organizer
  DDW
- Place of Presentation
  神戸
- Year and Date
  2014-05-03 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-24249046
[Presentation] 内視鏡的に特徴的な所見を観察しえた重症腸チフスの1例
- Author(s)
  梅田智子、小林拓、筋野智久、加藤裕佳子、清水清香、中野雅、常松令、芹澤宏、渡辺憲明、土本寛二、日比紀文
- Organizer
  第87回　日本消化器内視鏡学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24249046

1. WATANABE Mamoru (10175127)

# of Collaborated Projects: 17 results

# of Collaborated Products: 23 results
2. ISHIKAWA Hiromichi (20051667)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
3. KANAI Takanori (40245478)

# of Collaborated Projects: 5 results

# of Collaborated Products: 38 results
4. INOUE Nagamu (00232546)

# of Collaborated Projects: 5 results

# of Collaborated Products: 40 results
5. IWAO Yasushi (40168547)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
6. HARUHIKO Ogata (30177117)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
7. OKANO Hideyuki (60160694)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. NAGANUMA Makoto (00265810)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. OKAMOTO Susumu (70255446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. HISAMATSU Tadakazu (60255437)

# of Collaborated Projects: 2 results

# of Collaborated Products: 54 results
11. AISO Sadakazu (60138013)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. MAKABE Toshiaki (60095651)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. KOYASU Shigeo (90153684)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. ABE Masanori (70016624)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
15. HANDA Hiroshi (80107432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
16. SUEMATSU Makoto (00206385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. NOMURA Tatsuji (10072399)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
18. YAJIMA Tomoharu (70306710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
19. EZAKI Toshihiko (20255425)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. MORIMOTO Chikao (30119028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. TOSHIRO Sato (70365245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
22. TSUCHIMOTO Kanji (70155399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. WATANABE Noriaki (80167155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SUZUKI Tatsuo (40072409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. YAMADA Takaya (50191317)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. HAMADA Yoshiki (00137994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. ISHII Hiromasa (20051500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. KUMAI Koichiro (30101984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. FUNAKOSHI Shinsuke (20297352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KITAJIMA Masaki (90112672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. NAKANO Masaru (50265807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. AZUMA Toshihumi (00222612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. NISHIDA Jirou (50198470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. OHTEKI Toshiaki (50233200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. HACHIMURA Satoshi (40238019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. YAGITA Hideo (30182306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
37. AZUMA Miyuki (90255654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. NAKAZAWA Stsushi (90255456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
39. ONO Kairo (80160901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KOMATSU Haruko (20106678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. 田原利行 (80276245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. 新井潤 (30306683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. 合田宣人 (00245549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. 阿部啓子 (10151094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
45. 田之倉優 (60136786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. 清水誠 (30114507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. MORITA Minoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. YAGUCHI Tomonori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
49. SUGIYAMA Kazuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
50. 河上裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
51. 桜井敏晴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
52. 斎藤英胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
53. 岳野光洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hibi Toshifumi 日比 紀文

HIBI Toshifumi 日比 紀文

Research Projects

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Molecular characterization of Colitis Associated CancerPrincipal Investigator

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The role of fibrocyte in intestinal fibrosis and screening of anti-fibrotic therapy targeting fibrocyte.Principal Investigator

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特異抗体結合フェライトスーパービーズによる免疫標的療法の創成Principal Investigator

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Investigation of intestinal macrophage in contribution to gut immune homeostasis and its disruption in Crohn's diseasePrincipal Investigator

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潰瘍性大腸炎合併大腸癌に対する新しいサーベイランス法の確立-抗p53抗体の有用性Principal Investigator

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Identification of gastrointestinal epithelial stem cell and development of regeneration therapy for LBDPrincipal Investigator

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Hibi Toshifumi 日比紀文

HIBI Toshifumi 日比紀文