Nakase Hiroshi 仲瀬裕志

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NAKASE Hiroshi 仲瀬裕志

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Researcher Number	60362498
Other IDs
Affiliation (Current)	2024: 札幌医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2024: 札幌医科大学, 医学部, 教授 2015 – 2016: 京都大学, 医学研究科, 講師 2012 – 2015: 京都大学, 医学(系)研究科(研究院), 講師 2009 – 2011: Kyoto University, 医学研究科, 講師 2005 – 2007: Kyoto University, Department of Gastroenterology & Hepatology, Assistant Professor, 医学研究科, 講師 2004: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 47:Pharmaceutical sciences and related fields / Tumor biology / Laboratory medicine
Keywords	Principal Investigator 炎症性腸疾患 / エピゲノム / 腸管上皮細胞 / iPS細胞 / CXCL16 / basic FGF / 自然免疫 / サイトカイン / Organoid / IPS細胞 … More / メチル化 / オルガノイド / Dendritic cells / Chemokine / Inflammatory bowel disease / 樹状細胞 / ケモカイン / bone marrow cell / small intestine regenerating tube / bFGF / Basic FGF / 骨髄細胞 / 小腸再生チューブ / IL-1beta / IL-17 / 炎症性大腸発癌 / 炎症性大腸がん / Ral / 炎症性大腸発がん / マクロファージ / サイトメガロウイルス … More Except Principal Investigator 炎症性腸疾患 / エピゲノム / クローン病 / インターフェロン応答 / ヒストン修飾 / DOT1L / 時計遺伝子 / 間葉系幹細胞 / 骨髄間葉系幹細胞 / 潰瘍性大腸炎 / がん免疫 / M細胞 / 原発性硬化性胆管炎 / 肛門病変 / 細胞ファイバ / ゲノムアノテーション / メタゲノム / ゲノム多型 / ゲノムアッセンブル / スーパーコンピューター / メタゲノム解析 / 1細胞解析 / RNA-Seq / リシーケンシング / 新規ゲノム配列決定 / 次世代DNAシーケンサー / organoid / Paneth cell / NLRP3 / Crohn’s disease / RalGAPa2 / 肝細胞癌 / エピジェネティック治療 / 乳がん / 多発性骨髄腫 / iPS細胞 / 創薬 / 分化 / ヒト小腸吸収上皮細胞 / ヒト小腸オルガノイド / サイトメガロウィルス / 炎症性発癌 / サイトメガロウイルス / 肝発癌 / 概日時計 / 非アルコール性脂肪性肝炎 / 肝癌 / 肝がん / 概日リズム / 脂肪肝 / パーソナルゲノミクス解析 / 低頻度多型 / 希少変異 / パーソナルゲノミクス解析 / 日本人 / 疾患感受性遺伝子 / GTP結合蛋白質 / 炎症 / GTP結合蛋白室 / がん / がん抑制遺伝子 / Ral / 低分子量GTP結合蛋白質 / 腫瘍 / 幹細治療の最適化 / 骨髄移植 / 腸炎 / ニッチ / 骨髄－腸管連関 / 幹細胞ニッチ / サイトカイン / オートクライン / 免疫細胞 / inhibition / cytokines / nuclear / neutrophil / IBD / S100 proteins / Endocytosis / Macrophage / S100タンパク質 / LPS / 急性炎症 / トランスジェニックラット / マクロファージ Less

M細胞を介した腸管免疫応答に着目した原発性硬化性胆管炎の病態解明
- Principal Investigator
  
  石上敬介
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Elucidation of Inflammatory Bowel Disease Pathophysiology by Application of Organoid-iPS Cell SystemPrincipal Investigator
- Principal Investigator
  
  仲瀬裕志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
クローン病肛門病変に対する間葉系幹細胞と細胞ファイバ技術を融合した細胞療法の開発
- Principal Investigator
  
  永石歓和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
DOT1L阻害によるインターフェロン応答の機序解明とがん免疫療法への応用
- Principal Investigator
  
  鈴木拓
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
Functional analysis of small intestinal paneth cells in RalGAPa2 KO mice
- Principal Investigator
  
  林優希
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
肝細胞癌の分子標的治療と概日時計の関連
- Principal Investigator
  
  阿久津典之
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Analysis of anti-tumor mechanism underlying inhibition of a histone methyltransferase DOT1L
- Principal Investigator
  
  Suzuki Hiromu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Sapporo Medical University
Effect of circadian clock on liver carcinogenesis based on non-alcoholic steatohepatitis
- Principal Investigator
  
  SASAKI SHIGERU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
The effect of local reactivation of cytomegalovirus in ulcerative colitis-related colorectal cancer
- Principal Investigator
  
  Kawakami Kentaro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Development of human biopsy-derived intestinal organoids monolayers and application for pharmaceutical research
- Principal Investigator
  
  Mizuguchi Hiroyuki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka University
Development of personalized medcicine for inflammatory bowel disease based on control of epigenomePrincipal Investigator
- Principal Investigator
  
  NAKASE HIROSHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Sapporo Medical University
Personal genomics analysis in the inflammatory bowel disease family
- Principal Investigator
  
  Naishiro Yasuyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Platform for Advanced Genome Science
- Principal Investigator
  
  KOHARA Yuji
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  National Institute of Genetics
Reconstruction of Intestinal Epithelial Stem Cell Niche and Therapeutic Application
- Principal Investigator
  
  Arimura Yoshiaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Analysis of the mechanism responsible for the onset of ulcerative colitis using S100 transgenic rats
- Principal Investigator
  
  Ikemoto Masaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tenri Health Care University
Elucidation and therapeutic application of bone marrow-intestine coupling
- Principal Investigator
  
  Yamashita Kentaro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sapporo Medical University
Elucidation of roles of small GTPase Ral and its negative regulator RalGAP in tumorigenesis, and cancer invasion and metastasis
- Principal Investigator
  
  Horiuchi Hisanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Tohoku University
Functional analysis of small GTP binding protein Ral in colitis-associated cancerPrincipal Investigator
- Principal Investigator
  
  NAKASE Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Elucidation of mechanism of cytomegalovirus reactivation and infection in inflammatory bowel disease.Principal Investigator
- Principal Investigator
  
  NAKASE Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
New Therapy with CXCL16 Blocking for Inflammatory Bowel DiseasePrincipal Investigator
- Principal Investigator
  
  NAKASE Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Development of New device for Regeneration of small intestinal tissuePrincipal Investigator
- Principal Investigator
  
  NAKASE Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

[Book] 内科学書改訂第９版 Vol.4．腸結核.2019
- Author(s)
  仲瀬裕志
- Total Pages
  3672
- Publisher
  中山書店
- ISBN
  9784521747491
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 内科学書改訂第９版 Vol.4．膠原病の消化管病変．2019
- Author(s)
  仲瀬裕志
- Total Pages
  3672
- Publisher
  中山書店
- ISBN
  9784521747491
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 内科学書改訂第９版 Vol.4．腸管（型）Bechet病と単純性潰瘍2019
- Author(s)
  仲瀬裕志
- Total Pages
  3672
- Publisher
  中山書店
- ISBN
  9784521747491
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 最適治療を極める！クローン病2019
- Author(s)
  仲瀬裕志
- Total Pages
  78
- Publisher
  医学と看護社
- ISBN
  9784909888044
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 最適治療を極める！クローン病2019
- Author(s)
  仲瀬裕志
- Total Pages
  80
- Publisher
  医学と看護社
- ISBN
  9784909888044
- Data Source
  KAKENHI-PROJECT-18K07947
[Book] 最適治療を極める！潰瘍性大腸炎2018
- Author(s)
  仲瀬裕志
- Total Pages
  82
- Publisher
  医学と看護社
- ISBN
  9784906829873
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 最新多因子遺伝性疾患研究と遺伝カウンセリング2018
- Author(s)
  仲瀬裕志
- Total Pages
  300
- Publisher
  メディカルドゥ
- ISBN
  9784944157266
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 日本臨牀炎症性腸疾患（第２版）2018
- Author(s)
  仲瀬裕志
- Total Pages
  645
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-18H02799
[Book] 最適治療を極める！潰瘍性大腸炎2018
- Author(s)
  仲瀬裕志
- Total Pages
  82
- Publisher
  医学と看護社
- ISBN
  9784906829873
- Data Source
  KAKENHI-PROJECT-18K07947
[Book] 特集炎症性腸疾患攻略の手引き2014
- Author(s)
  仲瀬　裕志（監修・編集）
- Total Pages
  199
- Publisher
  東京：医学書院
- Data Source
  KAKENHI-PROJECT-24590941
[Book] シクロスポリン・タクロリムス炎症性腸疾患の内科的治療IBDを極める2011
- Author(s)
  仲瀬裕志
- Total Pages
  303
- Publisher
  Medical view社
- Data Source
  KAKENHI-PROJECT-21590810
[Book] 炎症性腸疾患を日常診療で診る2010
- Author(s)
  仲瀬裕志
- Total Pages
  211
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21590810
[Book] 最新医学特集炎症性腸疾患-最近の知見と今後解決されるべき問題点-2004
- Author(s)
  仲瀬裕志, 千葉勉
- Total Pages
  142
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Genomic analysis of an aggressive hepatic leiomyosarcoma case following treatment for hepatocellular carcinoma2024
- Author(s)
  Numata Yuto、Akutsu Noriyuki、Idogawa Masashi、Wagatsuma Kohei、Numata Yasunao、Ishigami Keisuike、Nakamura Tomoya、Hirano Takehiro、Kawakami Yujiro、Masaki Yoshiharu、Murota Ayako、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Hepatology Research
  
  Volume: Online ahead of print. Issue: 9 Pages: 859-865
- DOI
  10.1111/hepr.14034
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Downregulation of SMOC1 is associated with progression of colorectal traditional serrated adenomas2024
- Author(s)
  Aoki Hironori、Takasawa Akira、Yamamoto Eiichiro、Niinuma Takeshi、Yamano Hiro-o、Harada Taku、Kubo Toshiyuki、Yorozu Akira、Kitajima Hiroshi、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Shinohara Toshiya、Nakase Hiroshi、Sugai Tamotsu、Osanai Makoto、Suzuki Hiromu
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 24 Issue: 1 Pages: 24-24
- DOI
  10.1186/s12876-024-03175-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420, KAKENHI-PROJECT-23K24186
[Journal Article] Serum amyloid A1 recruits neutrophils to the invasive front of T1 colorectal cancers.2023
- Author(s)
  Yoshido A, Sudo G, Takasawa A, Aoki H, Kitajima H, Yamamoto E, Niinuma T, Harada T, Kubo T, Sasaki H, Ishiguro K, Yorozu A, Kai M, Katanuma A, Yamano HO, Osanai M, Nakase H, Suzuki H.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 38 Issue: 2 Pages: 301-310
- DOI
  10.1111/jgh.16055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07964, KAKENHI-PROJECT-21K15556, KAKENHI-PROJECT-21K16846, KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-23K24186, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-23K07420
[Journal Article] Generalized crystal-storing histiocytosis with noncirrhotic portal hypertension: an autopsy case report2023
- Author(s)
  Numata Yasunao、Sasaki Shigeru、Magara Kazufumi、Takasawa Akira、Sugawara Taro、Ohara Naruki、Akutsu Noriyuki、Hasegawa Tadashi、Osanai Makoto、Nakase Hiroshi
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 16 Issue: 3 Pages: 450-456
- DOI
  10.1007/s12328-023-01782-1
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Mesenchymal stem cellを知る2023
- Author(s)
  永石歓和、仲瀬裕志
- Journal Title
  
  消化器病サイエンス
  
  Volume: 7 Pages: 33-38
- Data Source
  KAKENHI-PROJECT-22K08058
[Journal Article] TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells2023
- Author(s)
  Kitajima Hiroshi、Maruyama Reo、Niinuma Takeshi、Yamamoto Eiichiro、Takasawa Akira、Takasawa Kumi、Ishiguro Kazuya、Tsuyada Akihiro、Suzuki Ryo、Sudo Gota、Kubo Toshiyuki、Idogawa Masashi、Toyota Mutsumi、Yoshido Ayano、Kumegawa Kohei、Kai Masahiro、Tokino Takashi、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 14 Issue: 7 Pages: 424-424
- DOI
  10.1038/s41419-023-05953-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16001, KAKENHI-PROJECT-21K07130, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-22K07173, KAKENHI-PROJECT-23K06426, KAKENHI-PROJECT-23K06445, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-23K24186
[Journal Article] Remitting Seronegative Symmetrical Synovitis with Pitting Edema (RS3PE) Syndrome Precedes the Development of Hepatocellular Carcinoma2022
- Author(s)
  Sae Ohwada 1 , Noriyuki Akutsu 1 , Yoshiharu Masaki 1 , Shigeru Sasaki 1 , Minoru Nagayama 2 , Yasutoshi Kimura 2 , Ichiro Takemasa 2 , Hiroki Takahashi 3 , Hiroshi Nakase 1
- Journal Title
  
  JMA Journal
  
  Volume: 5 Issue: 3 Pages: 393-397
- DOI
  10.31662/jmaj.2022-0066
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2022-07-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] 間葉系幹細胞を用いた炎症性疾患の細胞治療2022
- Author(s)
  永石歓和、仲瀬裕志
- Journal Title
  
  BIO Clinica
  
  Volume: 37 Pages: 87-90
- Data Source
  KAKENHI-PROJECT-22K08058
[Journal Article] A case of hepatocellular carcinoma with long-term survival by multidisciplinary treatment for cranial and skeletal muscle metastases2022
- Author(s)
  Akutsu Noriyuki、Kawakami Yujiro、Numata Yasunao、Hirano Takehiro、Wagatsuma Kohei、Ishigami Keisuke、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 15 Issue: 5 Pages: 960-967
- DOI
  10.1007/s12328-022-01669-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Genomic analysis of an aggressive case with metastatic intrahepatic mucinous cholangiocarcinoma.2022
- Author(s)
  Yoshiharu Masaki
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: 15 Issue: 4 Pages: 809-817
- DOI
  10.1007/s12328-022-01649-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09179, KAKENHI-PROJECT-20K08312, KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-22H04925
[Journal Article] Serum Soluble Fas Levels and Incidence of Liver Cancer in Nested Case?Control Study2022
- Author(s)
  Adachi Yasushi、Nojima Masanori、Mori Mitsuru、Kubo Toshiyuki、Akutsu Noriyuki、Sasaki Yasushi、Nakase Hiroshi、Lin Yingsong、Kurozawa Youichi、Wakai Kenji、Tamakoshi Akiko、for the Japan Collaborative Cohort Study
- Journal Title
  
  Cancer Epidemiology, Biomarkers & Prevention
  
  Volume: 32 Issue: 2 Pages: 260-265
- DOI
  10.1158/1055-9965.epi-22-0902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08390, KAKENHI-PROJECT-21K08801, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-20K08312, KAKENHI-PROJECT-22H04923
[Journal Article] Synergistic effect of IFN-γ and IL-1β on PD-L1 expression in hepatocellular carcinoma2022
- Author(s)
  Numata Yasunao、Akutsu Noriyuki、Ishigami Keisuke、Koide Hideyuki、Wagatsuma Kohei、Motoya Masayo、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 30 Pages: 101270-101270
- DOI
  10.1016/j.bbrep.2022.101270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Pharmacological Treatments Available for Immune-Checkpoint-Inhibitor-Induced Colitis2022
- Author(s)
  Ohwada Sae、Ishigami Keisuke、Akutsu Noriyuki、Nakase Hiroshi
- Journal Title
  
  Biomedicines
  
  Volume: 10 Issue: 6 Pages: 1334-1334
- DOI
  10.3390/biomedicines10061334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Should we continue or discontinue inflammatory bowel disease medication in patients with COVID-19?2022
- Author(s)
  Hayashi Yuki、Nakase Hiroshi、Hisamatsu Tadakazu
- Journal Title
  
  Gastroenterology
  
  Volume: In press Issue: 1 Pages: 338-339
- DOI
  10.1053/j.gastro.2022.03.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07919
[Journal Article] Positive Pattern Recognition System Using Alanine Aminotransferase, Type IV Collagen 7s, and E Value (Liver Stiffness) for the Diagnosis of Nonalcoholic Steatohepatitis Based on Natural History2022
- Author(s)
  Masayuki Tsujisaki 1 , Shigeru Sasaki 2 , Noriyuki Akutsu 2 , Takenori Takamura 1 , Tetsuyuki Igarashi 3 , Mitsuru Yoshimoto 1 , Hideto Itoh 1 , Yoshio Kurihara 4 , Hiroshi Nakase 2
- Journal Title
  
  JMA Journal
  
  Volume: 5 Issue: 2 Pages: 230-239
- DOI
  10.31662/jmaj.2021-0199
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2022-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] The Molecular Mechanisms of Intestinal Inflammation and Fibrosis in Crohn’s Disease2022
- Author(s)
  Hayashi Yuki、Nakase Hiroshi
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 13
- DOI
  10.3389/fphys.2022.845078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07919
[Journal Article] Monolayer platform using human biopsy-derived duodenal organoids for pharmaceutical research.2021
- Author(s)
  Yamashita T., Inui T., Yokota J., Kawakami K., Morinaga G., Takatani M., Hirayama D., Nomoto R., Ito K., Cui Y., Ruez S., Harada K., Kishimoto W., Nakase H., Mizuguchi H.
- Journal Title
  
  Mol. Ther. Methods. Clin. Dev.
  
  Volume: 22 Pages: 263-278
- DOI
  10.1016/j.omtm.2021.05.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20381, KAKENHI-PROJECT-19J21382, KAKENHI-PROJECT-21K18247
[Journal Article] Intestinal cancer in patients with Crohn's disease: A systematic review and meta-analysis2021
- Author(s)
  Motoi Uchino, Hiroki Ikeuchi, Keisuke Hata, Tomohiro Minagawa, Yuki Horio, Ryuichi Kuwahara, Shiro Nakamura, Kenji Watanabe, Masayuki Saruta, Toshimitsu Fujii, Taku Kobayashi, Ken Sugimoto, Fumihito Hirai, Motohiro Esaki, Sakiko Hiraoka, Katsuyoshi Matsuoka, Shinichiro Shinzaki, Minoru Matsuura, Nagamu Inoue, et al
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 36 Issue: 2 Pages: 329-336
- DOI
  10.1111/jgh.15229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08304, KAKENHI-PROJECT-19H01050, KAKENHI-PROJECT-18H02799
[Journal Article] Does anti-tumor necrosis factor alpha prevent the recurrence of Crohn's disease? Systematic review and meta-analysis2021
- Author(s)
  Uchino M, Ikeuchi H, Hata K, Minagawa T, Horio Y, Kuwahara R, Nakamura S, Watanabe K, Saruta M, Fujii T, Kobayashi T, Sugimoto K, Hirai F, Esaki M, Hiraoka S, Matsuoka K, Shinzaki S, Matsuura M, Inoue N, Nakase H, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: - Issue: 4 Pages: 864-872
- DOI
  10.1111/jgh.15288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-20K08304
[Journal Article] A case of hepatitis B virus and hepatitis C virus co-infection that achieved sustained virological response 12 following treatment with glecaprevir hydrate/pibrentasvir for 3 days2021
- Author(s)
  Numata Yasunao、Sasaki Shigeru、Akutsu Noriyuki、Hirano Takehiro、Wagatsuma Kohei、Kawakami Yujiro、Ishigami Keisuke、Nakase Hiroshi
- Journal Title
  
  Kanzo
  
  Volume: 62 Issue: 9 Pages: 578-584
- DOI
  10.2957/kanzo.62.578
- NAID
  130008086356
- ISSN
  0451-4203, 1881-3593
- Year and Date
  2021-09-01
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Activated macrophages promote invasion by early colorectal cancer via an interleukin 1β‐serum amyloid A1 axis2021
- Author(s)
  Sudo Gota、Aoki Hironori、Yamamoto Eiichiro、Takasawa Akira、Niinuma Takeshi、Yoshido Ayano、Kitajima Hiroshi、Yorozu Akira、Kubo Toshiyuki、Harada Taku、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Yamano Hiro‐o、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 10 Pages: 4151-4165
- DOI
  10.1111/cas.15080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08398, KAKENHI-PROJECT-20K17057, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846
[Journal Article] Immunoglobulin G4-related autoimmune hepatitis simultaneously concomitant with autoimmune pancreatitis: a case report2021
- Author(s)
  Yokoyama Yoshihiro、Akutsu Noriyuki、Numata Yasunao、Okuda Keiko、Morita Rena、Masaki Yoshiharu、Sasaki Hajime、Suzuki Ryo、Yabana Takashi、Arimura Yoshiaki、Kondo Yoshihiro、Nakase Hiroshi
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 14 Issue: 6 Pages: 1740-1745
- DOI
  10.1007/s12328-021-01509-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312, KAKENHI-PROJECT-21K15556
[Journal Article] Association of the Low-density Lipoprotein Cholesterol/High-density Lipoprotein Cholesterol Ratio with Glecaprevir-pibrentasvir Treatment2021
- Author(s)
  Akutsu Noriyuki、Sasaki Shigeru、Matsui Takeshi、Akashi Hirofumi、Yonezawa Kazuhiko、Ishigami Keisuke、Tsujisaki Masayuki、Isshiki Hiroyuki、Yawata Atsushi、Yamaoka Satoshi、Ban Toshihiro、Adachi Takeya、Nakahara Seiya、Takagi Hideyasu、Nakachi Kohei、Tanaka Katsunori、Hirano Takehiro、Nakase Hiroshi
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 21 Pages: 3369-3376
- DOI
  10.2169/internalmedicine.7098-21
- NAID
  130008110304
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-11-01
- Language
  English
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Comparison of culture media for human intestinal organoids from the viewpoint of pharmacokinetic studies.2021
- Author(s)
  Yokota J., Yamashita T., Inui T., Nomoto R., Kishimoto W., Nakase H., Mizuguchi H.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 566 Pages: 115-122
- DOI
  10.1016/j.bbrc.2021.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20381, KAKENHI-PROJECT-19J21382
[Journal Article] In vivo gene expression profile of human intestinal epithelial cells: from the viewpoint of drug metabolism and pharmacokinetics.2021
- Author(s)
  Takayama K., Ito K., Matsui A., Yamashita T., Kawakami K., Hirayama D., Kishimoto W., Nakase H., Mizuguchi H.
- Journal Title
  
  Drug. Metab. Dispos.
  
  Volume: 49 Issue: 3 Pages: 221-232
- DOI
  10.1124/dmd.120.000283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20381, KAKENHI-PROJECT-18H02799
[Journal Article] Mixed neuroendocrine non-neuroendocrine neoplasm of the gallbladder complicated by a pancreaticobiliary maljunction of a non-dilated biliary duct2021
- Author(s)
  Wagatsuma Kohei、Akita Kotaro、Motoya Masayo、Kimura Yasutoshi、Sugita Shintaro、Hirano Takehiro、Kawakami Yujiro、Numata Yasunao、Ishigami Keisuke、Masaki Yoshiharu、Murota Ayako、Shitani Masahiro、Akutsu Noriyuki、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 39 Pages: e27336-e27336
- DOI
  10.1097/md.0000000000027336
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease2021
- Author(s)
  Suzuki K, Kakuta Y, Naito T, Takagawa T, Hanai H, Araki H, Sasaki Y, Sakuraba H, Sasaki M, Hisamatsu T, Motoya S, Matsumoto T, Onodera M, Ishiguro Y, Nakase H, et al.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: - Issue: 1 Pages: 21-31
- DOI
  10.1093/ibd/izab004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K15740, KAKENHI-PROJECT-21K07961, KAKENHI-PROJECT-20K08304
[Journal Article] Dual EZH2 and G9a inhibition suppresses multiple myeloma cell proliferation by regulating the interferon signal and IRF4-MYC axis.2021
- Author(s)
  Ishiguro K, Kitajima H, Niinuma T, Maruyama R, Nishiyama N, Ohtani H, Sudo G, Toyota M, Sasaki H, Yamamoto E, Kai M, Nakase H, Suzuki H.
- Journal Title
  
  Cell Death Discovery
  
  Volume: 7 Issue: 1 Pages: 7-7
- DOI
  10.1038/s41420-020-00400-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17836, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-20K17057, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-21K15556
[Journal Article] Sustained hyperbilirubinemia following clarithromycin administration2021
- Author(s)
  Yamamoto Tomoka、Ishigami Keisuke、Ueno Akari、Akutsu Noriyuki、Numata Yasunao、Wagatsuma Kohei、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Medicine: Case Reports and Study Protocols
  
  Volume: 2 Issue: 2 Pages: e0057-e0057
- DOI
  10.1097/md9.0000000000000057
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Adrenomedullin for steroid-resistant ulcerative colitis: a randomized, double-blind, placebo-controlled phase-2a clinical trial.2021
- Author(s)
  Kita T, Ashizuka S, Ohmiya N, Yamamoto T, Kanai T, Motoya S, Hirai F, Nakase H, Moriyama T, Nakamura M, Suzuki Y, Kanmura S, Kobayashi T, Ohi H, Nozaki R, Mitsuyama K, Yamamoto S, Inatsu H, Watanabe K, Hibi T, Kitamura K.
- Journal Title
  
  J Gastroenterol
  
  Volume: 56 Issue: 2 Pages: 147-157
- DOI
  10.1007/s00535-020-01741-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18H02810, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-19K08481
[Journal Article] The characteristics of gastrointestinal symptoms for in patients with severe COVID-19: A systematic review and meta-analysis2021
- Author(s)
  Hayashi Y, Wagatsuma K, Nojima M, Yamakawa T, Ichimiya T, Yokoyama Y, Kazama T, Hirayama D, Nakase H
- Journal Title
  
  J Gastroenterol
  
  Volume: - Issue: 5 Pages: 409-420
- DOI
  10.1007/s00535-021-01778-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] The shining DIAMOND for evidence-based treatment strategies for Crohn’s disease.2020
- Author(s)
  Nakase H, Matsumoto T, Watanabe K, Hisamatsu T.
- Journal Title
  
  J Gastroenterol
  
  Volume: 55 Issue: 9 Pages: 824-832
- DOI
  10.1007/s00535-020-01702-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K07947
[Journal Article] Expert opinions on the current therapeutic management of inflammatory bowel disease during the COVID-19 pandemic: Japan IBD COVID-19 taskforce, intractable diseases, the health and labor sciences research.2020
- Author(s)
  akase H, Matsumoto T, Matsuura M, Iijima H, Matsuoka K, Ohmiya N, Ishihara S, Hirai F, Wagatsuma K, Yokoyama Y, Hisamatsu T.
- Journal Title
  
  Digestion
  
  Volume: - Issue: 5 Pages: 1-9
- DOI
  10.1159/000510502
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18K07971
[Journal Article] Exploratory study of the effectiveness of granulocyte and monocyte adsorptive apheresis before initiation of steroids in patients with active ulcerative colitis (EXPECT study): A multicenter prospective clinical trial.2020
- Author(s)
  Kakimoto K, Matsuura M, Takumi Fukuchi, Hongo H, Kimura T, Aoyama N, Okuda Y, Aomatsu K, Kamata N, Yokoyama Y, Mizuno C, Inoue T, Miyazaki T, Nakamura S, Higuchi K, Nakase H.
- Journal Title
  
  Crohn’s & Colitis 360.
  
  Volume: 2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Autophagy and autophagy-related diseases: a review.2020
- Author(s)
  Ichimiya T, Yamakawa T, Hirano T, Yokoyama Y, Hayashi Y, Hirayama D, Wagatsuma K, Itoi T, Nakase H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 23 Pages: 8974-8974
- DOI
  10.3390/ijms21238974
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Current diagnostic and therapeutic approaches to cytomegalovirus infections in ulcerative colitis patients based on clinical and basic research data.2020
- Author(s)
  Yokoyama Y, Yamakawa T, Hirano T, Kazama T, Hirayama D, Wagatsuma K, Nakase H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 7 Pages: 2438-2438
- DOI
  10.3390/ijms21072438
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Long-term follow-up of targeted biopsy yield (LOFTY Study) in ulcerative colitis surveillance colonoscopy.2020
- Author(s)
  Hata K, Ishihara S, Ajioka Y, Mitsuyama K, Watanabe K, Hanai H, Kunisaki R, Nakase H, Matsuda K, Iwakiri R, Hida N, Tanaka S, Takeuchi Y, Shinozaki M, Ogata N, Moriichi K, Hirai F, Sugihara K, Hisamatsu T, Suzuki Y, Watanabe M, Hibi T.
- Journal Title
  
  J Clin Med
  
  Volume: 18 Issue: 7 Pages: 2286-2286
- DOI
  10.3390/jcm9072286
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] CγP3A5 genotype as a potential pharmacodynamic biomarker for tacrolimus therapy in ulcerative colitis in Japanese patients.2020
- Author(s)
  Yamamoto Y, Nakase H, Matsuura M, Maruyama S, Masuda S.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 12 Pages: 4347-4347
- DOI
  10.3390/ijms21124347
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18H02588
[Journal Article] Contradictory effects of NLRP3 inflammasome regulatory mechanisms in colitis.2020
- Author(s)
  Wagatsuma K, Nakase H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 21 Pages: 8145-8145
- DOI
  10.3390/ijms21218145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K07947
[Journal Article] New paradigm of B-cell biology regarding the elucidation of a new mechanism of tissue fibrosis in IgG4-related disease.2020
- Author(s)
  Nakase H, Ishigami K.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 145 Issue: 3 Pages: 785-787
- DOI
  10.1016/j.jaci.2020.01.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] Treatment of inflammatory bowel disease from the immunological perspective.2020
- Author(s)
  Nakase H.
- Journal Title
  
  Immunol Med
  
  Volume: 43 Issue: 2 Pages: 79-86
- DOI
  10.1080/25785826.2020.1751934
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Upregulation of AEBP1 in endothelial cells promotes tumor angiogenesis in colorectal cancer2020
- Author(s)
  Yorozu Akira、Yamamoto Eiichiro、Niinuma Takeshi、Tsuyada Akihiro、Maruyama Reo、Kitajima Hiroshi、Numata Yuto、Kai Masahiro、Sudo Gota、Kubo Toshiyuki、Nishidate Toshihiko、Okita Kenji、Takemasa Ichiro、Nakase Hiroshi、Sugai Tamotsu、Takano Kenichi、Suzuki Hiromu
- Journal Title
  
  Cancer Science
  
  Volume: － Issue: 5 Pages: 1631-1644
- DOI
  10.1111/cas.14360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K15325, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K18736
[Journal Article] Author’s reply: acute serologic autoimmune hepatitis in the post-partum period2020
- Author(s)
  Akutsu Noriyuki、Ishigami Keisuke、Nakase Hiroshi
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 13 Issue: 4 Pages: 634-634
- DOI
  10.1007/s12328-020-01120-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Automatic, computer-aided determination of endoscopic and histological inflammation in patients with mild to moderate ulcerative colitis based on red density.2020
- Author(s)
  Bossuyt P, Nakase H, Vermeire S, de Hertogh G, Eelbode T, Ferrante M, Hasegawa T, Willekens H, Ikemoto Y, Makino T, Bisschops R.
- Journal Title
  
  GUT
  
  Volume: 69 Issue: 10 Pages: 1778-1786
- DOI
  10.1136/gutjnl-2019-320056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Long-Term Clinical Effectiveness of Ustekinumab in Patients With Crohn’s Disease: A Retrospective Cohort Study.2020
- Author(s)
  Itoh T, Maemoto A, Katsurada T, Tanaka H, Motoya S, Ueno N, Fujiya M, Ashida T, Hirayama D, Nakase H.
- Journal Title
  
  Crohn’s & Colitis 360.
  
  Volume: 2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Artificial intelligence-assisted endoscopy changes the definition of mucosal healing in ulcerative colitis.2020
- Author(s)
  Nakase H, Hirano T, Wagatsuma K, Ichimiya T, Yamakawa T, Yokoyama Y, Hayashi Y, Hirayama D, Kazama T, Yoshii S, Yamano HO.
- Journal Title
  
  Dig Endosc
  
  Volume: -
- DOI
  10.1111/den.13825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Development of anti-centromere antibody-positive autoimmune hepatitis after childbirth2020
- Author(s)
  Saito Mitsunobu、Akutsu Noriyuki、Numata Yasunao、Ishigami Keisuke、Sasaki Shigeru、Nakase Hiroshi
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 13 Issue: 5 Pages: 855-859
- DOI
  10.1007/s12328-020-01092-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08312
[Journal Article] Immunological mechanisms in inflammation-associated colon carcinogenesis.2020
- Author(s)
  Hirano T, Hirayama D, Wagatsuma K, Yamakawa T, Yokoyama Y, Nakase H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Issue: 9 Pages: 3062-3062
- DOI
  10.3390/ijms21093062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799, KAKENHI-PROJECT-18K07947
[Journal Article] Down-regulation of RalGTPase-Activating Protein Promotes Colitis-Associated Cancer via NLRP3 Inflammasome Activation2020
- Author(s)
  Iida Tomoya、Hirayama Daisuke、Minami Naoki、Matsuura Minoru、Wagatsuma Kohei、Kawakami Kentaro、Nagaishi Kanna、Nojima Masanori、Ikeuchi Hiroki、Hirota Seiichi、Shirakawa Ryutaro、Horiuchi Hisanori、Nakase Hiroshi
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 9 Issue: 2 Pages: 277-293
- DOI
  10.1016/j.jcmgh.2019.10.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07342, KAKENHI-PROJECT-18H02799
[Journal Article] A Rare Cause of Ileus in a Middle-Aged Japanese Woman.2019
- Author(s)
  Iida T, Arimura Y, Nakase H.
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 印刷中 Issue: 4 Pages: e43-e43
- DOI
  10.1016/j.cgh.2019.02.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09317
[Journal Article] Integrated Analysis of the Endoscopic, Pathological and Molecular Characteristics of Colorectal Tumorigenesis.2019
- Author(s)
  Suzuki H, Yamamoto E, Yamano HO, Nakase H, Sugai T.
- Journal Title
  
  Digestion.
  
  Volume: 99 Issue: 1 Pages: 33-38
- DOI
  10.1159/000494410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19H03518
[Journal Article] OPeNing the Epithelial Barrier: Osteopontin Preserves Gut Barrier Function During Intestinal Inflammation.2019
- Author(s)
  Nakase H.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 64 Issue: 2 Pages: 294-296
- DOI
  10.1007/s10620-018-5350-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-18H02799
[Journal Article] Withdrawal of thiopurines in Crohn’s disease treated with scheduled adalimumab maintenance: a prospective randomised clinical trial (DIAMOND2)2019
- Author(s)
  Hisamatsu Tadakazu、DIAMOND2 Study Group、Kato Shingo、Kunisaki Reiko、Matsuura Minoru、Nagahori Masakazu、Motoya Satoshi、Esaki Motohiro、Fukata Norimasa、Inoue Satoko、Sugaya Takeshi、Sakuraba Hirotake、Hirai Fumihito、Watanabe Kenji、Kanai Takanori、Naganuma Makoto、Nakase Hiroshi、et al.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Issue: 10 Pages: 860-870
- DOI
  10.1007/s00535-019-01582-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18KK0246
[Journal Article] Chronic Intestinal Pseudo-Obstruction Due to Al Amyloidosis: A Case Report and Literature Review2019
- Author(s)
  Iida Tomoya, Hirayama Daisuke, Sudo Gota, Mitsuhashi Kei, Igarashi Hisayoshi, Yamashita Kentaro, Yamano Hiroo, Nakase Hiroshi.
- Journal Title
  
  Clinical journal of gastroenterology
  
  Volume: 12 Issue: 2 Pages: 176-181
- DOI
  10.1007/s12328-018-0909-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] Current clinical issue of skin lesions in patients with inflammatory bowel disease.2019
- Author(s)
  Iida T, Hida T, Matsuura M, Uhara H, Nakase H.
- Journal Title
  
  Clin J Gastroenterol.
  
  Volume: 印刷中 Issue: 6 Pages: 501-510
- DOI
  10.1007/s12328-019-00958-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-18H02799
[Journal Article] Diversity of Gut Microbiota Affecting Serum Level of Undercarboxylated Osteocalcin in Patients with Crohn’s Disease2019
- Author(s)
  Wagatsuma Kohei、Yamada Satoshi、Ao Misora、Matsuura Minoru、Tsuji Hidemi、Iida Tomoya、Miyamoto Kentaro、Oka Kentaro、Takahashi Motomichi、Tanaka Kiyoshi、Nakase Hiroshi
- Journal Title
  
  Nutrients
  
  Volume: 11 Issue: 7 Pages: 1541-1541
- DOI
  10.3390/nu11071541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-19K11755, KAKENHI-PROJECT-19K17430, KAKENHI-PROJECT-18H02799
[Journal Article] UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells2019
- Author(s)
  Niinuma Takeshi、Kitajima Hiroshi、Kai Masahiro、Yamamoto Eiichiro、Yorozu Akira、Ishiguro Kazuya、Sasaki Hajime、Sudo Gota、Toyota Mutsumi、Hatahira Tomo、Maruyama Reo、Tokino Takashi、Nakase Hiroshi、Sugai Tamotsu、Suzuki Hiromu
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 11 Issue: 1 Pages: 70-70
- DOI
  10.1186/s13148-019-0668-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-19K18736, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700
[Journal Article] Therapeutic Efficacy and Adverse Events of Tacrolimus in Patients with Crohn’s Disease: Systematic Review and Meta-Analysis2019
- Author(s)
  Iida Tomoya、Nojima Masanori、Nakase Hiroshi
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 64 Issue: 10 Pages: 2945-2954
- DOI
  10.1007/s10620-019-05619-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799
[Journal Article] Optimizing the Use of Current Treatments and Emerging Therapeutic Approaches to Achieve Therapeutic Success in Patients with Inflammatory Bowel Disease.2019
- Author(s)
  Nakase H.
- Journal Title
  
  Gut Liver.
  
  Volume: 印刷中 Issue: 1 Pages: 7-19
- DOI
  10.5009/gnl18203
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317
[Journal Article] Influence of Pharmaceutical Formulation on the Mucosal Concentration of 5-Aminosalicylic Acid and <i>N</i>-Acetylmesalamine in Japanese Patients with Ulcerative Colitis2019
- Author(s)
  Yamamoto Y, Masuda S, Nakase H, Matsuura M, Maruyama S, Hisamatsu T, Suzuki Y, Matsubara K.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 1 Pages: 81-86
- DOI
  10.1248/bpb.b18-00561
- NAID
  130007542208
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-01-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08446, KAKENHI-PROJECT-18H02588, KAKENHI-PROJECT-18K07947
[Journal Article] Tumor recognition of peanut agglutinin-immobilized fluorescent nanospheres in biopsied human tissues.2019
- Author(s)
  Kumagai H, Yamada K, Nakai K, Kitamura T, Mohri K, Ukawa M, Tomono T, Eguchi T, Yoshizaki T, Fukuchi T, Yoshino T, Matsuura M, Tobita E, Pham W ;Nakase H, Sakuma S.
- Journal Title
  
  Eur J Pharm Biopharm.
  
  Volume: 136 Pages: 29-37
- DOI
  10.1016/j.ejpb.2019.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317
[Journal Article] The Etiology of Pancreatic Manifestations in Patients with Inflammatory Bowel Disease2019
- Author(s)
  Iida Tomoya、Wagatsuma Kohei、Hirayama Daisuke、Yokoyama Yoshihiro、Nakase Hiroshi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 8 Issue: 7 Pages: 916-916
- DOI
  10.3390/jcm8070916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] Concerns and side effects of azathioprine during adalimumab induction and maintenance therapy for Japanese patients with Crohn's disease: a sub-analysis of a prospective randomized clinical trial (DIAMOND study).2019
- Author(s)
  Hisamatsu T, Matsumoto T, Watanabe K,;Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 印刷中 Issue: 9 Pages: 1097-1104
- DOI
  10.1093/ecco-jcc/jjz030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18KK0246, KAKENHI-PROJECT-18H02799
[Journal Article] MEFV Gene-Related Enterocolitis Account for Some Cases Diagnosed as Inflammatory Bowel Disease Unclassified2019
- Author(s)
  Saito Daisuke、Hibi Noritaka、Ozaki Ryo、Kikuchi Oki、Sato Taro、Tokunaga Sotaro、Minowa Shintaro、Ikezaki Osamu、Mitsui Tatsuya、Miura Miki、Sakuraba Akihito、Hayashida Mari、Miyoshi Jun、Matsuura Minoru、Nakase Hiroshi、Hisamatsu Tadakazu
- Journal Title
  
  Digestion
  
  Volume: 1 Issue: 6 Pages: 1-9
- DOI
  10.1159/000502640
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799
[Journal Article] Evidence-based clinical practice guidelines for inflammatory bowel disease.2018
- Author(s)
  Matsuoka K, Kobayashi T, Ueno F, Matsui T, Hirai F, Inoue N, Kato J, Kobayashi K, Kobayashi K, Koganei K, Kunisaki R, Motoya S, Nagahori M, Nakase H, Omata F, Saruta M, Watanabe T, Tanaka T, Kanai T, Noguchi Y, Takahashi K, Watanabe K, Hibi T, Suzuki Y, Watanabe M, Sugano K, Shimosegawa T.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 53 Issue: 3 Pages: 305-353
- DOI
  10.1007/s00535-018-1439-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799
[Journal Article] DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling2018
- Author(s)
  Ishiguro Kazuya、Kitajima Hiroshi、Niinuma Takeshi、Ishida Tadao、Maruyama Reo、Ikeda Hiroshi、Hayashi Toshiaki、Sasaki Hajime、Wakasugi Hideki、Nishiyama Koyo、Shindo Tetsuya、Yamamoto Eiichiro、Kai Masahiro、Sasaki Yasushi、Tokino Takashi、Nakase Hiroshi、Suzuki Hiromu
- Journal Title
  
  Haematologica
  
  Volume: 104 Issue: 1 Pages: 155-165
- DOI
  10.3324/haematol.2018.191262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15959, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-19K17438, KAKENHI-PROJECT-19K17468, KAKENHI-PROJECT-19H03518
[Journal Article] Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors2018
- Author(s)
  Harada T、Yamamoto E、Yamano HO、Aoki H、Matsushita HO、Yoshikawa K、Takagi R、Harada E、Tanaka Y、Yoshida Y、Eizuka M、Yorozu A、Sudo G、Kitajima H、Niinuma T、Kai M、Sasaki Y、Tokino Takashi、Sugai T、Nakase H、Suzuki H
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 53 Issue: 12 Pages: 1241-1252
- DOI
  10.1007/s00535-018-1481-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-16H06279
[Journal Article] Usefulness of fecal calprotectin by monoclonal antibody testing in adult Japanese with inflammatory bowel diseases: a prospective multicenter study.2018
- Author(s)
  Nakamura S, Imaeda H, Nishikawa H, Iimuro M, Matsuura M, Oka H, Oku J, Miyazaki T, Honda H, Watanabe K, Nakase H, Andoh A.
- Journal Title
  
  Intest Res.
  
  Volume: 16 Issue: 4 Pages: 554-562
- DOI
  10.5217/ir.2018.00027
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] Impact of Autophagy of Innate Immune Cells on Inflammatory Bowel Disease.2018
- Author(s)
  Iida T, Yokoyama Y, Wagatsuma K, Hirayama D, Nakase H.
- Journal Title
  
  Cells.
  
  Volume: 8 Issue: 1 Pages: 7-7
- DOI
  10.3390/cells8010007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317
[Journal Article] Effect of elemental diet combined with infliximab dose escalation in patients with Crohn’s disease with loss of response to infliximab: CERISIER trial.2018
- Author(s)
  Hisamatsu T, Kunisaki R, Nakamura S, Tsujikawa T, Hirai F, Nakase H, Watanabe K, Yokoyama K, Nagahori M, Kanai T, Naganuma M, Michimae H, Andoh A, Yamada A, Yokoyama T, Kamata N, Tanaka S, Suzuki Y, Hibi T, Watanabe M.
- Journal Title
  
  Intest Res.
  
  Volume: 16 Issue: 3 Pages: 494-498
- DOI
  10.5217/ir.2018.16.3.494
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799
[Journal Article] Clinical and pharmacokinetic factors associated with adalimumab-induced mucosal healing in patients with Crohn’s disease.2018
- Author(s)
  Watanabe K, Matsumoto T, Hisamatsu T, Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T.
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 16 Pages: 542-549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria.2018
- Author(s)
  Nakajima A, Vogelzang A, Maruya M, Miyajima M, Murata M, Son A, Kuwahara T, Tsuruyama T, Yamada S, Matsuura M, Nakase H, Peterson DA, Fagarasan S, Suzuki K.
- Journal Title
  
  J Exp Med.
  
  Volume: 215 Issue: 8 Pages: 2019-2034
- DOI
  10.1084/jem.20180427
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08833, KAKENHI-PROJECT-16H02632, KAKENHI-PROJECT-18H02799
[Journal Article] The Incidence and Risk Factors of Venous Thromboembolism in Patients with Inflammatory Bowel Disease: A Prospective Multicenter Cohort Study2018
- Author(s)
  Ando Katsuyoshi、Fujiya Mikihiro、Nomura Yoshiki、Inaba Yuhei、Sugiyama Yuya、Kobayashi Yu、Iwama Takuya、Ijiri Masami、Takahashi Keitaro、Ueno Nobuhiro、Kashima Shin、Moriichi Kentaro、Tanabe Hiroki、Mizukami Yusuke、Akasaka Kazumi、Fujii Satoshi、Yamada Satoshi、Nakase Hiroshi、Okumura Toshikatsu
- Journal Title
  
  Digestion
  
  Volume: NA Issue: 4 Pages: 1-9
- DOI
  10.1159/000495289
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-17K15911, KAKENHI-PROJECT-18K15770, KAKENHI-PROJECT-19K17430
[Journal Article] Predicting outcomes to optimize disease management in inflammatory bowel disease in Japan: their differences and similarities to Western countries.2018
- Author(s)
  Kobayashi T, Hisamatsu T, Suzuki Y, Ogata H, Andoh A, Araki T, Hokari R, Iijima H, Ikeuchi H, Ishiguro Y, Kato S, Kunisai R, Matsumoto T, Motoya S, Nagahori M, Nakamura S, Nakase H, Tsujikawa T, Sasaki M, Yokoyama K, Yoshimura N, Watanabe K, Katafuchi M, Watanabe M, Hibi T.
- Journal Title
  
  Intest Res.
  
  Volume: 16 Issue: 2 Pages: 168-177
- DOI
  10.5217/ir.2018.16.2.168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07947
[Journal Article] Subtypes of the Type II Pit Pattern Reflect Distinct Molecular Subclasses in the Serrated Neoplastic Pathway.2018
- Author(s)
  Aoki H, Yamamoto E, Yamano HO, Sugai T, Kimura T, Tanaka Y, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Nakaoka M, Yoshida Y, Harada T, Sudo G, Eizuka M, Yorozu A, Kitajima H, Niinuma T, Kai M, Nojima M, Suzuki H, Nakase H.
- Journal Title
  
  Dig Dis Sci.
  
  Volume: 15 Issue: 7 Pages: 1920-1928
- DOI
  10.1007/s10620-018-5016-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-15K08973
[Journal Article] Efficacy of endoscopic balloon dilation for small bowel strictures in patients with Crohn’s disease: a nationwide, multi-centre, open-label, prospective cohort study.2018
- Author(s)
  Hirai F, Andoh A, Ueno F, Watanabe K, Ohmiya N, Nakase H, Kato S, Esaki M, Endo Y, Yamamoto H, Matsui T, Iida M, Hibi T, Watanabe M, Suzuki Y, Matsumoto T.
- Journal Title
  
  J Crohns Colitis.
  
  Volume: 12 Issue: 4 Pages: 394-401
- DOI
  10.1093/ecco-jcc/jjx159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-18H02799
[Journal Article] Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease.2018
- Author(s)
  Watanabe K, Matsumoto T, Hisamatsu T, Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
- Journal Title
  
  Clin Gastroenterol Hepatol.
  
  Volume: 16 Issue: 4 Pages: 542-549
- DOI
  10.1016/j.cgh.2017.10.036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02799
[Journal Article] Evaluation of a novel fluorescent nanobeacon for targeted imaging of Thomsen-Friedenreich associated colorectal cancer.2017
- Author(s)
  Nakase H, Sakuma S, Fukuchi T, Yoshino T, Mohri K, Miyata K, Kumagai H, Hiwatari KI, Tsubaki K, Ikejima T, Tobita E, Zhu M, Wilson KJ, Washington K, Gore JC, Pham W.
- Journal Title
  
  Int J Nanomedicine.
  
  Volume: 12 Pages: 1747-1755
- DOI
  10.2147/ijn.s124174
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-16H06279
[Journal Article] 骨髄―腸管連関の解明と治療応用2017
- Author(s)
  永石歓和，山下健太郎，有村佳昭，仲瀬裕志
- Journal Title
  
  Medical Science Digest
  
  Volume: 43 Pages: 72-75
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460975
[Journal Article] Epigenetic silencing of SMOC1 in traditional serrated adenoma and colorectal cancer.2017
- Author(s)
  Aoki H, Yamamoto E, Takasawa A, Niinuma T, Yamano HO, Harada T, Matsushita HO, Yoshikawa K, Takagi R, Harada E, Tanaka Y, Yoshida Y, Aoyama T, Eizuka M, Yorozu A, Kitajima H, Kai M, Sawada N, Sugai T, Nakase H, Suzuki H.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 4 Pages: 4707-4721
- DOI
  10.18632/oncotarget.23523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-17K09387, KAKENHI-PROJECT-17K15956, KAKENHI-PROJECT-15H04299, KAKENHI-PROJECT-16K19352, KAKENHI-PROJECT-16K21250, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-15K08973
[Journal Article] The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis.2017
- Author(s)
  Hirayama D, Iida T, Nakase H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 1 Pages: 92-92
- DOI
  10.3390/ijms19010092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-15K08972, KAKENHI-PROJECT-16H06279
[Journal Article] Significance of measurement of serum trough level and anti-drug antibody of adalimumab as personalised pharmacokinetics in patients with Crohn's disease: a subanalysis of the DIAMOND trial.2017
- Author(s)
  Nakase H, Motoya S, Matsumoto T, Watanabe K, Hisamatsu T, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group.
- Journal Title
  
  Aliment Pharmacol Ther.
  
  Volume: 46 Issue: 9 Pages: 873-882
- DOI
  10.1111/apt.14318
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-16H06279
[Journal Article] A Unique Cause of Persistent Diarrhea.2017
- Author(s)
  Iida T, Yamashita K, Nakase H.
- Journal Title
  
  Gastroenterology.
  
  Volume: 152 Issue: 6 Pages: 1291-1292
- DOI
  10.1053/j.gastro.2016.11.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09317
[Journal Article] Efficacy of Indigo naturalis in a Multicenter Randomized Controlled Trial of Patients with Ulcerative Colitis2017
- Author(s)
  .Naganuma M, Sugimoto S, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka K, Hisamatsu T, Watanabe K, Mizuno S, Suda W, Hattori M, Fukuda S, Hirayama A, Abe T, Watanabe M, Hibi T, Suzuki Y, Kanai T
- Journal Title
  
  Gastroenterology
  
  Volume: 4 Issue: 4 Pages: 935-947
- DOI
  10.1053/j.gastro.2017.11.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02534, KAKENHI-PROJECT-15J00981, KAKENHI-PROJECT-15K08564, KAKENHI-PROJECT-15K21364, KAKENHI-PROJECT-18K07947, KAKENHI-PROJECT-16K09326
[Journal Article] 骨髄―腸管連関の解明と治療応用2017
- Author(s)
  永石歓和，山下健太郎，有村佳昭，仲瀬裕志
- Journal Title
  
  Medical Science Digest
  
  Volume: 43 Pages: 72-75
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08972
[Journal Article] Osteopontin attenuates acute gastrointestinal graft-versus-host disease by preventing apoptosis of intestinal epithelial cells.2017
- Author(s)
  Kawakami K, Minami N, Matsuura M, Iida T, Toyonaga T, Nagaishi K, Arimura Y, Fujimiya M, Uede T, Nakase H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 485 Issue: 2 Pages: 468-475
- DOI
  10.1016/j.bbrc.2017.02.047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09317, KAKENHI-PROJECT-15K08972
[Journal Article] Is Osteopontin a Friend or Foe of Cell Apoptosis in Inflammatory Gastrointestinal and Liver Diseases?2017
- Author(s)
  Iida T, Wagatsuma K, Hirayama D, Nakase H.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 19 Issue: 1 Pages: 7-7
- DOI
  10.3390/ijms19010007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08972
[Journal Article] CD68 on rat macrophages binds tightly to S100A8 and S100A9 and helps to regulate the cells’ immune functions2016
- Author(s)
  Kohki Okada, Satoshi Arai, Hiroshi Itoh, Souichi Adachi, Hiroshi Nakase, Masaki Ikemoto
- Journal Title
  
  J Leukoc Biol
  
  Volume: 100 Pages: 1093-1104
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460663
[Journal Article] Autocrine pathways involving S100A8 and/or S100A9 that are postulated to to regulate the immunological functions of macrophages in rats2016
- Author(s)
  Kohki Okada, Satoshi Arai, Hiroshi Nakase, Hisashi Kohno, Fumihiko Nakamura, Mayu Takeda, Yoshinobu Toda, Hiroshi Itoh, Souichi Adachi, Masaki Ikemoto
- Journal Title
  
  BBRC
  
  Volume: 456 Pages: 415-420
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460663
[Journal Article] Autocrine pathways involving S100A8 and/or S100A9 that are postulated to regulate the immunological functions of macrophages in rats2015
- Author(s)
  Kohki Okada, Satoshi Arai, Hiroshi Nakase, Hisashi Kohno, Fumihiko Nakamura, Mayu Takeda, Yoshinobu Toda, Hiroshi Itoh, Souichi Adachi, Masaki Ikemoto1
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume: 456 Pages: 415-420
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460663
[Journal Article] Autocrine pathways involving S100A8 and/or S100A9 that are postulated to to regulate the immunological functions of macrophages in rats2015
- Author(s)
  Okada K, Arai S, Nakase H, Kohno H, Nakamura F, Takeda M, Toda Y, Itoh H, Adachi S, Ikemoto M
- Journal Title
  
  Biochem Biophys Res Commun (BBRC)
  
  Volume: 456 Pages: 415-420
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460663
[Journal Article] Efficacy and safety of granulocyte and monocyte adsorption apheresis for ulcerative colitis : a meta-analysis2014
- Author(s)
  Yoshino T, Nakase H, Minami N, Yamada S, Matsuura M, Yazumi S, Chiba T
- Journal Title
  
  Dig Liver Dis
  
  Volume: 46 Issue: 3 Pages: 219-26
- DOI
  10.1016/j.dld.2013.10.011
- NAID
  120005385891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590940, KAKENHI-PROJECT-24590941, KAKENHI-PROJECT-25860532
[Journal Article] Pulmonary Mycobacterium avium infection in a patient with2014
- Author(s)
  Hirano T, Matsuura M, Nakase H
- Journal Title
  
  Case Rep Gastroenterol
  
  Volume: 8 Issue: 2 Pages: 182-185
- DOI
  10.1159/000363376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Unique endoscopic findings of colitis-associated colorectal cancer in a patient with ulcerative colitis and Lynch syndrome2014
- Author(s)
  Minami N, Yoshio T, Nakase H
- Journal Title
  
  J Crohns Colitis
  
  Volume: ８ Issue: 4 Pages: 336-337
- DOI
  10.1016/j.crohns.2013.11.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Mesenteric lymphoma with chylous ascites2014
- Author(s)
  Arasawa S, Nakase H, Minami N
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 8 Pages: 1570-1570
- DOI
  10.1111/jgh.12635
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease2014
- Author(s)
  Honzawa Y, Nakase H, Shiokawa M, Yoshino T, Imaeda H, Matsuura M, Kodama Y, Ikeuchi H, Andoh A, Sakai Y, Nagata K, Chiba T
- Journal Title
  
  Gut
  
  Volume: 63 Issue: 12 Pages: 1902-12
- DOI
  10.1136/gutjnl-2013-305632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590940, KAKENHI-PROJECT-24590940, KAKENHI-PROJECT-24590941, KAKENHI-PROJECT-26893122
[Journal Article] Use of capsule endoscopy in patients with Crohn's disease in Japan: a multicenter survey.2014
- Author(s)
  Esaki M, Matsumoto T, Watanabe K, Arakawa T, Naito Y, Matsuura M, Nakase H, Hibi T, Matsumoto T, Nouda S, Higuchi K, Ohmiya N, Goto H, Kurokawa S, Motoya S, Watanabe M.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29(1) Issue: 1 Pages: 96-101
- DOI
  10.1111/jgh.12411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249046, KAKENHI-PROJECT-24590941
[Journal Article] Therapeutic effect of intensve granulocyte and monocyte adsorption apheresis combined with thiopurines for steroids and biologics naive Japanese patients with early-diagnosed Crohn's Disease2014
- Author(s)
  Fukuchi T, Nakase H, Ubukata S, Matsuura M, Yoshino T, Toyonaga T, Koga H, Eguchi T, Yamashita H, Ito D, Ashida K.
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 13 Issue: 1 Pages: 124-124
- DOI
  10.1186/1471-230x-14-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] A randomized clinical trial of mesalazine suppository: The usefulness and problems of central review of evaluations of colonic mucosal findings.2014
- Author(s)
  Kobayashi K, Hirai F, Naganuma M, Watanabe K, Ando T, Nakase H, Matsuoka K, Watanabe M.
- Journal Title
  
  J Crohns Colitis
  
  Volume: 8 Issue: 11 Pages: 1444-1453
- DOI
  10.1016/j.crohns.2014.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Long-term efficacy of infliximab for refractory ulcerative colitis: results from a single center experience.2014
- Author(s)
  Yamada S, Yoshino T, Minami N, Toyonaga T, Honzawa Y, Matsuura M, Nakase H.
- Journal Title
  
  BMC Gastroenterol
  
  Volume: 14 Issue: 1 Pages: 80-80
- DOI
  10.1186/1471-230x-14-80
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590941, KAKENHI-PROJECT-26893122
[Journal Article] Efficacy and safety of granulocye and monocyte adsorption apheresis for ulcerative colitis: a meta-analysis2014
- Author(s)
  Yoshino T, Nakase H, MInami N, Yamada S, Matsuura M, Yazaumi S, Chiba T
- Journal Title
  
  Dig Liver Dis
  
  Volume: 46 Pages: 219-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Unique endoscopic findings of colitis-associated cololectal cancer in a patient with ulcerative colitis and Lynch syndrome2014
- Author(s)
  Minami N, Yoshino T, Nakase H
- Journal Title
  
  J Crohns Colitis
  
  Volume: 8 Pages: 336-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590941
[Journal Article] Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling2013
- Author(s)
  Yamamoto S, Nakase H, Matsuura M, Honzawa Y, Matsumura K, Uza N, Yamaguchi Y, Mizoguchi E, Chiba T
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 305 Issue: 3 Pages: G241-G249
- DOI
  10.1152/ajpgi.00480.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590940, KAKENHI-PROJECT-24590941, KAKENHI-PROJECT-24659363
[Journal Article] Refractoriness of intestinal Behçet's disease with myelodysplastic syndrome involving trisomy 8 to medical therapies - our case experience and review of the literature2013
- Author(s)
  Toyonaga T, Nakase H, Matsuura M, Minami N, Yamada S, Honzawa Y, Hukata N, Yoshino T, Chiba T, Okazaki K
- Journal Title
  
  Digestion
  
  Volume: 88 Issue: 4 Pages: 217-21
- DOI
  10.1159/000355341
- NAID
  120005385869
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590940, KAKENHI-PROJECT-24590941
[Journal Article] Tacrolimus is a promising as a rescue therapy for severe ulcerative colitis, but never experimental trial2011
- Author(s)
  Nakase H, Yamamoto S, Matsuura M, Chiba T.
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 413-414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Tacrolimus suppresses IL-12/IL-23p40 in Crohn's disease and heals fistulae refractory to anti-TNF-αtherapy2011
- Author(s)
  Nakase H, Uza N, Matsuura M, Chiba T
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 979-80
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Tacrolimus : rescue therapy or experimental drug for severe ulcerative colitis2011
- Author(s)
  Nakase H, Yamamoto S, Matsuura M, Chiba T
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 413-4
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Ectopic pancreas at the jejunum.2011
- Author(s)
  Takeda Y, Nakase H, Chiba T.
- Journal Title
  
  Digest liver Dis
  
  Volume: 43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Role of Heat Shock Protein 47 in Intestinal Fibrosis of Experimental Colitis.2011
- Author(s)
  Kitamura H, Yamamoto S, Nakase H, Matsuura M, Honzawa Y, Matsumura K, Takeda Y, Uza N, Nagata K, Chiba T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 404 Pages: 599-604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Effect and Safety of Granulocyte-Monocyte Adsorption Apheresis for UC Patients Positive for Cytomegalovirus in Comparison with Immunosuppressants2011
- Author(s)
  Yoshino T, Nakase H, Matsuura M, Matsumura K, Honzawa Y, Fukuchi T, Watanabe K, Murano M, Tsujikawa T, Fukunaga K, Matsumoto T, Chiba T
- Journal Title
  
  Digestion
  
  Volume: 84 Issue: 1 Pages: 3-9
- DOI
  10.1159/000321911
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Importance of CXCL16 as a biomarker for granulocytapheresis in patients with Crohn's disease2011
- Author(s)
  Nakase H, Uza N, Matsuura M, Chiba T
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17 Issue: 10 Pages: 2211-2
- DOI
  10.1002/ibd.21657
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] tential role of granulocyte/monocyte adsorptive apheresis for UC concomitant CMV infecti2011
- Author(s)
  Nakase H, et al
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 497-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Clinical significance of serum diamine oxidase activity in inflammatory bowel disease.-importance of evaluation of small intestinal permeability-.2011
- Author(s)
  Honzawa Y, Nakase H, Matsuura M, Chiba T.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Tacrolimus therapy as an alternative to thiopurines for maintaining remission inpatients with refractory ulcerative colitis2011
- Author(s)
  Yamamoto S, Nakase H, et al.
- Journal Title
  
  Journal of Clinical Gastroenterology
  
  Volume: (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Fat restriction is associated with impaired quality of life (QOL) in patients with ulcerative colitis and Crohn' s disease.2011
- Author(s)
  Kuwabara A, Nakase H, Tsuji H, Shide K Chiba T, Inagaki N, Tanaka K.
- Journal Title
  
  Ulcers Volume
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Involvement of Mycobacterium avium subspecies para tuberculosis with TNF-αproduction from Macrophage-possible link between MAP and immune response in Crohn's disease-Inflammatory Bowel Disease2011
- Author(s)
  Nakase H, Tamaki H, Matsuura M, Chiba T, Okazaki K
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 17 Issue: 11 Pages: 140-2
- DOI
  10.1002/ibd.21750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810, KAKENHI-PROJECT-23590940
[Journal Article] Positive finding of Colonic PCR for CMV-DNA is not false positive but warning for treating patients with UC refractory to immunosuppressive therapies.2011
- Author(s)
  Nakase H, Yoshino T, Matsumura K, Honzawa Y, Yamamoto S, Matsuura M, Chiba T.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Potential role of granulocyte/monocyte adsorptive apheresis for ulcerative colitis with concomitant CMV infection.2011
- Author(s)
  Nakase H, Matsuura M, Chiba T.
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 497-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Effect and Safety of Granulocyte-Monocyte Adsorption Apheresis for UC Patients Positive for Cytomegalovirus in Comparison with Immunosuppressants.2011
- Author(s)
  Yoshino T, Nakase H, Matsuura M, Matsumura K, Honzawa Y, Fukuchi T, Watanabe K, Murano M, Tsujikawa T, Fukunaga K, Matsumoto T, Chiba T.
- Journal Title
  
  Digestion
  
  Volume: 84 Pages: 3-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Positive finding of Colonic PCR for CMV-DNA is not false positive but warning for treating patients with UC refractory to immunosuppressive therapies Inflammatory Bowel Disease2011
- Author(s)
  Nakase H Yoshino T, Matsumura K, Honzawa Y, Yamamoto S, Matsuura M, Chiba T
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 17 Issue: 2 Pages: 13-4
- DOI
  10.1002/ibd.21401
- ISSN
  1078-0998
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation2011
- Author(s)
  Uza N, Nakase H, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Inoue S, Mikami S, Matsuura M, Shimaoka T, Kume N, Minami M, Yonehara S, Ikeuchi H, Chiba T
- Journal Title
  
  Gut
  
  Volume: 60 Issue: 11 Pages: 1494-1505
- DOI
  10.1136/gut.2010.221879
- NAID
  120003497105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-21590810, KAKENHI-PROJECT-23590361, KAKENHI-PROJECT-23590940
[Journal Article] Potential role of granulocyte/monocyte adsorptive apheresis for ulcerative colitis with concomitant CMV infection2011
- Author(s)
  Nakase H, Matsuura M, Chiba T
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 33 Pages: 497-8
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] 特集炎症性消化器疾患の治療と発癌予防潰瘍性大腸炎における新たな薬剤をどう使うか-免疫抑制剤-2010
- Author(s)
  仲瀬裕志, 松浦稔, 千葉勉
- Journal Title
  
  消化器の臨床
  
  Volume: 13 Pages: 659-663
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Bifidobacterium longum BB536の潰瘍性大腸炎に対する治療機序の解明2010
- Author(s)
  難波和美、伊藤彩子、仲瀬裕志、千葉勉
- Journal Title
  
  食品工業
  
  Volume: 53 Pages: 44-51
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] TNFαis an important pathogenic factor contributing to reactivation of cytomegalovirus in inflamed mucosa of colon in patients with ulcerative colitis-lesson from clinical experiences-.2010
- Author(s)
  Nakase H, Chiba T
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Issue: 4 Pages: 550-551
- DOI
  10.1002/ibd.21047
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] メサラジン製剤(pH依存型放出調節製剤)が有効であった直腸炎型潰瘍性大腸炎の1例2010
- Author(s)
  仲瀬裕志
- Journal Title
  
  消化器内科
  
  Volume: 51 Pages: 577-580
- NAID
  40018275446
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Efficacy and safety of infliximab as rescue therapy for ulcerative colitis refractory to tacrolimus.2010
- Author(s)
  Yamamoto S, Nakase H, Matsuura M, Honzawa Y, Masuda S, Inui Ken-ichi, Chiba T.
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 25 Pages: 886-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Immunosuppressive effects of tacrolimus on macrophages ameliorate experimental colitis.2010
- Author(s)
  Yoshino T, Nakase H, et al.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Pages: 2022-2033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] TNF α is an important pathogenic factor contributing to reactivation of cytomegalovirus in inflamed mucosa of colon in patients with ulcerative colitis.-lesson from clinical experiences-.2010
- Author(s)
  Nakase H, Chiba T.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Pages: 550-551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Sustained abdominal discomfort in a 57-year-old-woman.2010
- Author(s)
  Nishiura H, Nakase H, Chiba T.
- Journal Title
  
  Gut
  
  Volume: 59 Pages: 578-594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Pedunculated Cavernous Hemangioma mimicking inflammatory fibroid polyp in a Patient with Ulcerative Colitis.2010
- Author(s)
  Ueda K, Nakase H, Yaku H, Honzawa, Y, Chiba T.
- Journal Title
  
  Endoscopy
  
  Volume: 42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Cytomegalovirus affects clinical outcome of infliximab therapy on patients with ulcerative colitis refractory to tacrolimus.2010
- Author(s)
  Nakase H, Yamamoto S, Matsuura M, Honzawa Y, Chiba T.
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 32 Pages: 510-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Heat shock protein 47 can be a new target molecule for intestinal fibrosis related to inflammatory bowel disease.2010
- Author(s)
  Honzawa Y, Nakase H, Takeda Y, Nagata K, Chiba T.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Pages: 2004-2006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Efficacy of Oral Tacrolimus on Intestinal Behcet's Disease.2010
- Author(s)
  Matsumura K, Nakase H, Chiba T.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Pages: 188-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Successful Endoscopic Dilation Treatment of Small Intestinal Stricture that occurred during Chemotherapy for Malignant Lymphoma.2010
- Author(s)
  Honzawa Y, Kondo M, Hayakumo T, Matsuura M, Nakase H.
- Journal Title
  
  Case report in Gastroenterol
  
  Volume: 4 Pages: 323-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Immunosuppressive effects of tacrolimus on macrophages ameliorate experimental colitis2010
- Author(s)
  Yoshino T, Nakase H, Honzawa Y, Matsumura K, Yamamoto S, Takeda Y, Ueno S, Uza N, Masuda S, Inui K, Chiba T
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Issue: 12 Pages: 2022-33
- DOI
  10.1002/ibd.21318
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates : A randomized phase 2, placebo-controlled trial.2010
- Author(s)
  Nakase H, Fujiyama Y, Oshitani N, Oga T, Nonomura K, Matsuoka T, Murayama T, Teramukai S, Chiba T, Narumiya S.
- Journal Title
  
  Inflammatory Bowel Disease
  
  Volume: 16 Pages: 731-733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Gastrointestinal follicular lymphoma : review of the literature.2010
- Author(s)
  Yamamoto S, Nakase H, Yamashita K, Matsuura M, Takada M, Kawanami C, Chiba T.
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 45 Pages: 370-388
- NAID
  10027215379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Oral tacrolimus (FK 506) in refractory pediatric ulcerative colitis. Authors' reply2010
- Author(s)
  Yamamoto S, Nakase H, Chiba T.
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 31 Pages: 677-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] IBDドラッグ&マニュピュレーションIBD治療におけるシクロスポリン、タクロリムスの使用法2010
- Author(s)
  仲瀬裕志, 本澤有介, 千葉勉
- Journal Title
  
  IBD research 4
  
  Volume: 4 Pages: 44-47
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Heat shock protein 47 is a new candidate molecule as anti-fibrotic treatment of Crohn's disease.2010
- Author(s)
  Nakase H, Honzawa Y, Chiba T.
- Journal Title
  
  Aliment Pharmacol Ther
  
  Volume: 31 Pages: 926-927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Q&A-専門医に聞くIBDとIBSはどのように違うのですか?2010
- Author(s)
  仲瀬裕志, 本澤有介, 松浦稔, 千葉勉
- Journal Title
  
  IBD research
  
  Volume: 4 Pages: 74-76
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Modulation of Th1/Th2 balance by infliximab improves hyperthyroidism associated with flare-up of ulcerative colitis.2009
- Author(s)
  Matsumura K, Nakase H, et al
- Journal Title
  
  Inflamm Bowel Dis 15
  
  Pages: 967-968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] The Effect of Proteasome Inhibitor MG132 on Experimental Inflammatory Bowel Disease.2009
- Author(s)
  Inoue S, Nakase, H, et al
- Journal Title
  
  Clin Exp Immunol 156
  
  Pages: 172-182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] 小さな小腸炎症性病変Crohn病の小病変の診断:術後再発病変診断の意義2009
- Author(s)
  仲瀬裕志
- Journal Title
  
  胃と腸 44
  
  Pages: 967-974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Alteration of CXCR4 expression and Th1/Th2 balance of peripheral CD4 positive Tcells can be a biomarker for Leukocytapheresis therapy for patients with refractory ulcerative colitis.2009
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Inflamm Bowel Dis 15
  
  Pages: 963-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590810
[Journal Article] Clinical features of Japanese patients with colonic angiodysplasia.2008
- Author(s)
  Ueno S, Nakase H, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Administration of PEG-interferon to a patient with ulcerative colitis and chronic hepatitis C correlated with reduced colonic inflammation and reversal of peripheral Th1/Th2 ratios2007
- Author(s)
  Kasahara, K, Nakase, H, Uza, N, Ueno, S, Matsuura, M, Mikami, S, Inoue, S, Chiba, T
- Journal Title
  
  Case Reports in Gastroenterology 1
  
  Pages: 157-161
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies.2007
- Author(s)
  Yoshino T, Nakase H, et. al.
- Journal Title
  
  Inflamm Bowel Dis. 13
  
  Pages: 1516-1521
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Hemosuccus pancreaticus2007
- Author(s)
  Maruyama, J, Nakase, H, Chiba, T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 446-446
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Image of Month : Follicular Lymphoma with Small Intestinal Involvement Detected by Double-Balloon Enteroscopy2007
- Author(s)
  Yamamoto, S, Nakase, H, Kawanami, C
- Journal Title
  
  Clin Gastroenterol Hepatol 5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Localized cytomegalovirus reactivation after radiotherapy for high grade gastric lymphoma2007
- Author(s)
  Saga, K, Fukui, T, Kato, Y, Komeda, T, Nakase, H, Watanabe, N, Nishio, A, Chiba, T
- Journal Title
  
  Gastrointest Endosc 65
  
  Pages: 545-547
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Open label trial of Clarithromycin therapy in Japanese patients with Crohn's disease.2007
- Author(s)
  Inoue S, Nakase H, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. 22
  
  Pages: 984-988
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Clincal Challenge and Image in GI : Unique gastrointestinal involvement in a patient with Henoch-Schonlein purpura2007
- Author(s)
  Ueo, T, Nakase, H, Chiba, T
- Journal Title
  
  Gastroenterology 133
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Magnifying endoscopic view of primary follicular lymphoma at duodenal papilla2007
- Author(s)
  Nakase, H, Matsuura, M, Mikami, S, Chiba, T
- Journal Title
  
  Intern Med 46
  
  Pages: 141-142
- NAID
  130000078579
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] A case of ileal heterotopic pancreas with repeated melena2007
- Author(s)
  Endo, Y, Yazumi, S, Kimura, Y, Uza, N, Matsuura, M, Kodama, Y, Nakase, H, Chiba, T
- Journal Title
  
  Gastrointest Endosc 65
  
  Pages: 156-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Cross-Primed CD8(+) Cytotoxic T cells Induce Severe Helicobacter-associated Gastritis in the Absence of CD4(+) T cells2007
- Author(s)
  Fukui, T, Nishio, A, Okazaki, K, Kasahara, K, Saga, K, Tanaka, J, Uza, N, Ueno, S, Kido, M, Ohashi, S, Asada, M, Nakase, H, Watanabe, N, Chiba, T
- Journal Title
  
  Helicobacter 12
  
  Pages: 486-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Open label trial of Clarithromycin therapy in Japanese patients with Crohn's disease2007
- Author(s)
  Inoue, S, Nakase, H, Matsuura, M, Ueno, S, Uza, N, Kitamura, H, Mikami, S, Tamaki, H, Kasahara, K, Chiba, T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 984-988
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Involvement of cytomegalovirus infection in the ileal lesions of the patient with Behhet's disease2007
- Author(s)
  Mikami, S, Nakase, H, Ueno, S, Matsuura, M, Sakurai, T, Chiba, T
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 802-803
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Education and Imaging. Gastrointestinal : ileal ulcers induced by non-steroidal anti-inflammatory drugs2007
- Author(s)
  H.,Matsuura, M, Nakase, H, Nakamura, F, Yoshihide, Ueda, Y, Mikami S, Yoshino, T, Ueno, S, Uza, N, Chiba, T
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 1346-1346
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Importance of early detection of cytomegalovirus infection in refractory inflammatory bowel disease2007
- Author(s)
  Nakase, H, Yoshino, T, Ueno, S, Uza, N, Mikami, S, Matsuura, M, Chiba, T
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 364-364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Image of Month : Ileal polyposis caused by follicular lymphoma2007
- Author(s)
  Matsuura, M, Nakase, H, Mochizuki, N
- Journal Title
  
  Clin Gastroenterol Hepatol 5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Magnified endoscopic view of primary follicular lymphoma at the duodenal papilla2007
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Intern Med 46
  
  Pages: 141-142
- NAID
  130000078579
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Importance of early detection of cytomegalovirus infection in refractory inflammatory bowel disease.2007
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 364-364
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Rescue therapy with tacrolimus for a patient with severe ulcerative colitis refractory to combination leukocytapheresis and high dose of corticosteroid therapy2007
- Author(s)
  Nakase, H, Mikami, S, Matsuura, M, Ueno, S, Inoue, S, Kitamura, H, Kasahara, K, Yoshino, T, Takeda, Y, Chiba, T
- Journal Title
  
  Intern Med 46
  
  Pages: 717-720
- NAID
  130000076720
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Diagnosis and treatment of obscure GI bleeding with double balloon endoscopy2007
- Author(s)
  Nakase, H, Matsuura, M, Mikami, S, Chiba, T
- Journal Title
  
  Gastrointest Endosc 66(3 Suppl)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Pneumatosis cystoides intestinalis at ascending colon2007
- Author(s)
  Mikami, S, Nakase, H, Sakurai, T, Chiba, T, Shimizu, S
- Journal Title
  
  J Gastroenterol Hepatol 22
  
  Pages: 760-760
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies2007
- Author(s)
  Yoshino, T, Nakase, H, Ueno, S, Uza, N, Inoue, S, Mikami, S, Matsuura, M, Oomori, K, Sakurai, T, Nagayama, S, Hasegawa, S, Sakai, Y, Chiba, T
- Journal Title
  
  Inflamm Bowel Dis 13
  
  Pages: 1516-1521
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui T, Nakase H, et al.
- Journal Title
  
  GUT 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Solitary rectal ulcer syndrome with ulcerative colitis.2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastrointest Endosc 63
  
  Pages: 355-356
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Human Thioredoxin-1 Ameliorates Experimental Murine Colitis in Association with Suppressed Macrophage Inhibitory Factor2006
- Author(s)
  Tamaki H, Nakase H, et al.
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1110-1121
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Image of the Month : Meckel's diverticulum with an enterolith.2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastroenterology (印刷中)
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Clinical challenges and images in GI. Meckel's diverticulum with an enterolith2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastroenterology 131
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Human Thioredoxin-I Ameliorates Experimental Murine Colitis in Association with Suppressed Macrophage Inhibitory Factor Production2006
- Author(s)
  Tamaki, H, Nakamura, H, Nishio, A, Nakase, H, Ueno, S, Uza, N, Kido, M, Inoue, S, Mikami, S, Asada, M, Kiriya, K, Kitamura, H, Ohashi, S, Fukui, T, Kawasaki, K, Matsuura, M, Ishii, Y, Okazaki, K, Yodoi, J, Chiba, T
- Journal Title
  
  Gastroenterology 131
  
  Pages: 1110-1121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Protective role ofredox-active thioredoxin-1 for severe acute pancreatitis2006
- Author(s)
  Ohashi S, Nakase H, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 290
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Cytomegalovirus infection in patients with ulcerative colitis diagnosed by quantitative real-time PCR analysis.2006
- Author(s)
  Kou T, Nakase H, et al.
- Journal Title
  
  Dig Dis Sci 51
  
  Pages: 1052-1055
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Solitary rectal ulcer syndrome with ulcerative colitis.2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 63
  
  Pages: 355-356
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Solitary rectal ulcer syndrome with ulcerative colitis2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastrointestinal Endoscopy. 63
  
  Pages: 355-356
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Specific Antibodies Against Recombinant Protein of Insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's Disease.2006
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Inflammatory Bowel Disease 12
  
  Pages: 62-69
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Caecal cancer associated with longstanding Crohn's disease2006
- Author(s)
  Uza, N, Nakase, H, Kuwabara, Y, Fujii, S, Chiba, T
- Journal Title
  
  Lancet 368(9549)
  
  Pages: 1842-1842
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Caecal cancer associated with longstanding Crohn's disease2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Lancet 368
  
  Pages: 1842-1842
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Protective role of redox-active thioredoxin-1 for severe acute pancreatitis2006
- Author(s)
  Ohashi S, Nakase H, et al.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol 290
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Specific Antibodies Against Recombinant Protein of Insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's Disease.2006
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Inflamm Bowel Disease 12
  
  Pages: 62-69
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Gastric mucosal hyperplasia via up-regulation of gastrin induced by persistent activation of gastric innate immunity in MHC class II-deficient mice.2006
- Author(s)
  Fukui H, Nakase H, et al.
- Journal Title
  
  Gut 55
  
  Pages: 607-615
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Specific antibodies against recombinant proteins of insertion element 900 of mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's Disease2006
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Inflammatory bowel disease 12
  
  Pages: 62-69
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Cytomegalovirus infection in patients with ulcerative colitis diagnosed by quantitative real-time PCR analysis2006
- Author(s)
  Kou, T, Nakase, H, Tamaki, H, Kudo, T, Nishio, A, Chiba, T
- Journal Title
  
  Dig Dis Sci 51
  
  Pages: 1052-1055
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Rectal carcinoid tumor mimicking colonic adenomatous lesion2006
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 62
  
  Pages: 976-977
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Meckel's diverticulum with an enterolith.2006
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastroenterology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Rectal Carcinoid Tumor Mimicking Colonic Adenomatous Lesion.2005
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Gastrointestinal Endoscopy 62
  
  Pages: 976-977
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Possible role of REG I{alpha} protein in ulcerative colitis and colitic cancer.2005
- Author(s)
  Sekikawa A, Nakase H, et al.
- Journal Title
  
  Gut 54
  
  Pages: 1437-1444
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Refractory enterovesical and duodenocolic fistulas in Crohn's disease successfully managed with tacrolimus.2005
- Author(s)
  Fukuda A, Nakase H, et al.
- Journal Title
  
  J Gastroenterol (印刷中)
- NAID
  10015710243
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Rectal Carcinoid Tumor Mimicking Colonic Adenomatous Lesion.2005
- Author(s)
  Nakase H, et al.
- Journal Title
  
  Gastrointest Endosc 62
  
  Pages: 976-977
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.2005
- Author(s)
  Matsuura M, Nakase H, et al.
- Journal Title
  
  Gastroenterology (印刷中)
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Colonic ameboma2005
- Author(s)
  Matsuura M, Nakase H, et al.
- Journal Title
  
  Gastrointest Endosc (発表予定)
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Environmental pollutant tributyltin promotes Th2 polarization and exacerbates airway inflammation.2004
- Author(s)
  Kato T, Nakase H, et al.
- Journal Title
  
  Eur J Immunol. 34
  
  Pages: 1312-1321
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Characteristics of gastric B-cell lymphoma of mucosa-associated lymphoid tissue type involving multiple organs.2004
- Author(s)
  Iwano M, Nakase H, et al.
- Journal Title
  
  J Gastroenterol. 39
  
  Pages: 739-746
- NAID
  80016835116
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Metastatic thyroid lymphoma to gastroduodenum2004
- Author(s)
  Katayama M, Nakase H, et al.
- Journal Title
  
  Gastrointest Endosc 60
  
  Pages: 605-606
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Clinical features of Japanese patients with colonic angiodysplasia
- Author(s)
  Ueno, S, Nakase, H, Kasahara, K, Uza, N, Kitamura, H, Inoue, S, Mikami, S, Matsuura, M, Chiba, T
- Journal Title
  
  J Gastroenterol Hepatol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Clinical features of Japanese patients with colonic angiodysplasia.
- Author(s)
  Ueno S, Nakase H, et. al.
- Journal Title
  
  J Gastroenterol Hepatol. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] The effect of medical treatment on patients with fistulizing Crohn's Disease : Our experience with a retrospective study
- Author(s)
  Uza, N, Nakase, H, Ueno, S, Inoue, S, Mikami, S, Tamaki, H, Matsuura, M, Chiba, T
- Journal Title
  
  Intern Med (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] Meckel's diverticulum with an enteolith
- Author(s)
  Uza N, Nakase H, et al.
- Journal Title
  
  Gastroenterology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590590
[Journal Article] Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele-Importanceof inflammation in the appendiceal orifice related to ulcerative colitis
- Author(s)
  Takeda, Y, Nakase, H, Mikami, S, Inoue, T, Satou, S, Sakai, Y, Chiba, T
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Journal Article] The importance of diagnosis of concomitant cytomegalovirus infection in patients with intestinal Bechet's disease
- Author(s)
  Yoshino, T, Nakase, H, Mikami, S, Nio, M, Ueno, S, Uza, N, Ohmori, K, Manabe, T, Chiba, T
- Journal Title
  
  Inflamm Bowel Dis (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Patent] 腸上皮様細胞及びその作製方法2020
- Inventor(s)
  水口裕之、高山和雄、山下智起、仲瀬裕志、川上賢太郎、平山大輔
- Industrial Property Rights Holder
  水口裕之、高山和雄、山下智起、仲瀬裕志、川上賢太郎、平山大輔
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-016592
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] ICT を活用した IBD 遠隔連携診療体制の構築と運用2024
- Author(s)
  林優希，横山佳浩，風間友江，平山大輔，仲瀬裕志
- Organizer
  第20回日本消化管学会総会学術集会ワークショップ
- Data Source
  KAKENHI-PROJECT-21K07919
[Presentation] 炎症性腸疾患における遠隔連携診療ネットワークの構築と運用2024
- Author(s)
  林優希，横山佳浩，風間友江，平山大輔，仲瀬裕志
- Organizer
  第109回日本消化器病学会総会ワークショップ
- Data Source
  KAKENHI-PROJECT-21K07919
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化し，免疫調整津薬の効果を増強する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，廣橋良彦，粂川昂平，関口翔平，佐々木基，甲斐正広，鳥越俊彦，仲瀬裕志，鈴木拓．
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，粂川昴平，関口翔平，佐々木基，甲斐正広，仲瀬裕志，鈴木拓．
- Organizer
  第16回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 多発性骨髄腫においてDOT1L阻害は自然免疫シグナルを活性化する．2023
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，塚原智英，廣橋良彦，粂川昴平，関口翔平，吉戸文乃，甲斐正広，鳥越俊彦，仲瀬裕志，鈴木拓．
- Organizer
  第127回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 高齢者肝細胞癌に対する経皮的ラジオ波焼灼療法の検討2023
- Author(s)
  沼田泰尚, 阿久津典之, 我妻康平, 平野雄大, 川上裕次郎, 石上敬介, 柾木喜晴, 室田文子, 佐々木茂, 仲瀬裕志
- Organizer
  日本高齢消化器病学
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 当科の核酸アナログ治療20年の検討2023
- Author(s)
  阿久津典之, 佐々木茂, 沼田泰尚, 平野雄大, 我妻康平, 石上敬介, 川上裕次郎, 柾木喜晴, 室田文子, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 切除不能肝細胞癌に対する分子標的治療症例の複数レジメン治療の有用性2023
- Author(s)
  阿久津典之, 沼田泰尚, 平野雄大, 我妻康平, 川上裕次郎, 柾木喜晴, 石上敬介, 室田文子, 佐々木茂, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] DOT1L inhibition activates innate immune signaling in multiple myeloma.2023
- Author(s)
  Ishiguro K, Kitajima H, Niinuma T, Maruyama R, Tsukahara T, Hirohashi Y, Kumegawa K, Sekiguchi S, Sasaki S, Kai M, Torigoe T, Nakase H, Suzuki H.
- Organizer
  2nd JCA-AACR Precision Cancer Medicine International Conference.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 当科における原発性硬化性胆管炎(PSC)症例の検討2023
- Author(s)
  沼田泰尚, 阿久津典之, 世戸凌太, 中村隼人, 浪岡万由子, 廣部洋輔, 三浦克与志, 平野雄大, 我妻康平, 川上裕次郎, 石上敬介, 柾木喜晴, 室田文子, 佐々木茂, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 肝硬変の成因と病態の推移　2018年以降に当科で加療した肝硬変症例の検討2023
- Author(s)
  阿久津典之, 沼田泰尚, 石上敬介, 我妻康平, 平野雄大, 川上裕次郎, 佐々木茂, 仲瀬裕志
- Organizer
  日本肝臓学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 創薬応用を目的としたMDR1-knockoutヒト腸管オルガノイドの樹立2022
- Author(s)
  乾達也、横田純平、野元隆我、山下智起、岡田健太郎、岸本航、仲瀬裕志、水口裕之
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 転移性肺腫瘍に対するEUS-FNAにて診断した後腹膜原発の絨毛癌の1例2022
- Author(s)
  廣部洋輔, 川上裕次郎, 越前栄次朗, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之, 本谷雅代, 佐々木茂, 辻脇光洋, 舛森直哉, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 5年の経過で消失した多発肝炎症性偽腫瘍の1例2022
- Author(s)
  浪岡万由子, 阿久津典之, 石上敬介, 三浦克予志, 平野雄大, 我妻康平, 沼田泰尚, 佐々木茂, 永山稔, 菅原太郎, 長谷川匡, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 多発性骨髄腫においてDOT1L阻害は免疫シグナルを活性化する2022
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，粂川昴平，関口翔平，甲斐正広，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 小腸原発Gastrointestinal stromal tumor(GIST)に対するイマチニブ投与中に肝転移破裂、腹腔内出血をきたした1例2022
- Author(s)
  山本智香, 室田文子, 沼田泰尚, 川上裕次郎, 石上敬介, 柾木喜晴, 阿久津典之, 本谷雅代, 佐々木茂, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 当院における悪性肝門部胆管狭窄に対するドレナージの成績2022
- Author(s)
  室田文子, 我妻康平, 川上裕次郎, 沼田泰尚, 石上敬介, 柾木喜晴, 阿久津典之, 本谷雅代, 佐々木茂, 仲瀬裕志
- Organizer
  日本胆道学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] INTERIM ANALYSIS OF A MULTICENTER REGISTRY STUDY OF COVID-19 INFECTED PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN JAPAN (J-COSMOS).2022
- Author(s)
  Y.Hayashi , H.Nakase , D.Hirayama, T.Matsumoto, M.Matsuura, H.Iijima, K.Matsuoka, N.Ohmiya, S.Ishihara, F.Hirai, T.Hisamatsu, and J-COSMOS group.
- Organizer
  Digestive Disease Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07919
[Presentation] 胆道鏡下生検検体で遺伝パネル検査を施行しえた切除不能胆嚢管癌の1例2022
- Author(s)
  越前栄次朗, 川上裕次郎, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之, 本谷雅代, 佐々木茂, 杉田真太郎, 櫻井晃洋, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] FDG-PETを契機に診断に至ったIgG4関連消化管病変の1例2022
- Author(s)
  沼田有斗, 川上裕次郎, 越前栄次郎, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之, 本谷雅代, 佐々木茂, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] ヒト生検由来腸管オルガノイド（enteroid）培養法の比較検討2022
- Author(s)
  横田純平、山下智起、乾達也、岸本航、仲瀬裕志、水口裕之
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 陰茎転移をきたした膵尾部癌の1例2022
- Author(s)
  井澤朋, 川上裕次郎, 世戸凌太, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之, 本谷雅代, 舛森直哉, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 高精度な薬物動態評価が可能なMDR1-KOヒト腸管オルガノイドの樹立2022
- Author(s)
  乾達也、横田純平、野元隆我、山下智起, 岡田健太郎, 岸本航, 仲瀬裕志, 水口裕之
- Organizer
  細胞アッセイ研究会シンポジウム：細胞アッセイ技術の現状と将来
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 難治性腹水を呈した全身性結晶蓄積性組織球症の1例2022
- Author(s)
  大原成喜, 沼田泰尚, 沼田有斗, 谷口正浩, 越前栄次朗, 平野雄大, 我妻康平, 川上裕次郎, 柾木喜晴, 石上敬介, 室田文子, 阿久津典之, 本谷雅代, 佐々木茂, 真柄和史, 菅原太郎, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 胆膵癌におけるEUS-FNA検体を用いたMSI検査2022
- Author(s)
  川上裕次郎, 本谷雅代, 仲瀬裕志, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之
- Organizer
  日本消化器内視鏡学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 治療困難肝内結石に対するSpyGlass DSを用いた胆道鏡下治療の検討2022
- Author(s)
  越前栄次朗, 川上裕次郎, 我妻康平, 沼田泰尚, 石上敬介, 柾木喜晴, 室田文子, 阿久津典之, 本谷雅代, 佐々木茂, 仲瀬裕志
- Organizer
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] DOT1L阻害は乳がん細胞のインターフェロンシグナルを活性化する2022
- Author(s)
  鈴木拓，丸山玲緒，北嶋洋志，石黒一也，新沼猛，粂川昴平，吉戸文乃，甲斐正広，仲瀬裕志．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 活性化マクロファージはIL-1β-SAA1 axisを介して早期大腸がんの浸潤を促進する2022
- Author(s)
  須藤豪太，山本英一郎，青木敬則，高澤啓，吉戸文乃，新沼猛，久保俊之，原田拓，萬顕，北嶋洋志，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進してアポトーシスを抑制する2022
- Author(s)
  北嶋洋志，丸山玲緒，新沼猛，高澤啓，山本英一郎，石黒一也，吉戸文乃，甲斐正広，小山内誠，時野隆至，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] Serum amyloid A1は好中球をリクルートして早期大腸癌の浸潤を促進する2022
- Author(s)
  吉戸文乃，須藤豪太，高澤啓，北嶋洋志，山本英一郎，青木敬則，新沼猛，石黒一也，久保俊之，原田拓，甲斐正広，小山内誠，仲瀬裕志，鈴木拓．
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24186
[Presentation] 術前に肝細胞癌との鑑別が困難であった肝血管筋脂肪腫の2切除例2022
- Author(s)
  加藤透, 永山稔, 木村康利, 今村将史, 久木田和晴, 村上武志, 水口徹, 阿久津典之, 佐々木茂, 仲瀬裕志, 竹政伊知朗
- Organizer
  日本臨床外科学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 高齢者切除不能膵癌患者に対するGEM+nabPTX療法の有効性と安全性2022
- Author(s)
  大和田紗恵, 室田文子, 本谷雅代, 我妻康平, 沼田泰尚, 川上裕次郎, 石上敬介, 柾木喜晴, 阿久津典之, 佐々木茂, 仲瀬裕志
- Organizer
  日本高齢消化器病学会
- Data Source
  KAKENHI-PROJECT-20K08312
[Presentation] 慢性胃炎・胃がん関連長鎖non-coding RNAはストレス顆粒形成を促進し、アポトーシスを抑制する2021
- Author(s)
  北嶋洋志, 丸山玲緒, 新沼猛, 山本英一郎, 高澤啓, 石黒一也, 甲斐正広, 吉戸文乃, 小山内誠, 時野隆至, 仲瀬裕志, 鈴木拓
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] 慢性胃炎・胃がん関連長鎖non-coding RNAによるストレス顆粒形成の促進と発がん機構の解析2021
- Author(s)
  北嶋洋志, 丸山玲緒, 新沼猛, 高澤啓, 山本英一郎, 石黒一也, 甲斐正広, 吉戸文乃, 小山内誠, 時野隆至, 仲瀬裕志, 鈴木拓
- Organizer
  第101回北海道医学大会腫瘍系分科会・第123回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] DOT1L阻害は乳がん細胞のトランスクリプトームおよびエピゲノムシグネチャーを変化させる．2021
- Author(s)
  鈴木拓，丸山玲緒，北嶋洋志，新沼猛，石黒一也，粂川昴平，吉戸文乃，佐々木基，山本英一郎，甲斐正広，仲瀬裕志．
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 同一個人由来のヒト生検由来腸管オルガノイドとヒトiPS細胞由来腸管オルガノイドの比較検討2021
- Author(s)
  乾達也、山下智起、野元隆我、横田純平、川上賢太郎、岸本航、仲瀬裕志、水口裕之
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] A long non-coding RNA associated with chronic gastritis and gastric cancer inhibits apoptosis by promoting stress granule formation2021
- Author(s)
  Hiroshi Kitajima, Reo Maruyama, Akira Takasawa, Takeshi Niinuma, Eiichiro Yamamoto, Kazuya Ishiguro, Ayano Yoshido, Masahiro Kai, Makoto Osanai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] Identification of a long non-coding RNA associated with gastritis and gastric cancer2021
- Author(s)
  Hiroshi Kitajima, Reo Maruyama, Takeshi Niinuma, Akira Takasawa, Eiichiro Yamamoto, Kazuya Ishiguro, Masahiro Kai, Ayano Yoshido, Hiroshi Nakase, Takashi Tokino, Hiromu Suzuki
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] A long non-coding RNA associated with chronic gastritis and gastric cancer promotes stress granule formation and inhibits apoptosis2021
- Author(s)
  Hiroshi Kitajima, Reo Maruyama, Akira Takasawa, Takeshi Niinuma, Eiichiro Yamamoto, Kazuya Ishiguro, Ayano Yoshido, Masahiro Kai, Makoto Osanai, Takashi Tokino, Hiroshi Nakase, Hiromu Suzuki
- Organizer
  39回札幌国際がんシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] エピジェネティック阻害剤のGIST細胞におけるエピゲノム修飾，遺伝子発現への影響の統合解析．2021
- Author(s)
  吉戸文乃，須藤豪太，北嶋洋志，新沼猛，甲斐正広，原田拓，佐々木基，久保俊之，仲瀬裕志，菅井有，鈴木拓．
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 胃炎胃がん関連lncRNAはストレス顆粒形成を促進し，アポトーシスを抑制する．2021
- Author(s)
  北嶋洋志，丸山玲緒，髙澤啓，新沼猛，山本英一郎，石黒一也，吉戸文乃，甲斐正広，小山内誠，時野隆至，仲瀬裕志，鈴木拓．
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 生検由来ヒト腸管オルガノイドの薬物動態試験への応用2021
- Author(s)
  山下智起、乾達也、横田純平、川上賢太郎、平山大輔、野元隆我、岸本航、仲瀬裕志、水口裕之
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 慢性胃炎および胃がんに関連する長鎖non-coding RNA結合タンパク質の探索2021
- Author(s)
  北嶋洋志、丸山玲緒、山本英一郎、新沼猛、甲斐正広、仲瀬裕志、時野隆至、鈴木拓
- Organizer
  第14回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] 薬物動態学的応用のためのヒト腸管オルガノイド培養法の比較2021
- Author(s)
  横田純平、山下智起、乾達也、岸本航、仲瀬裕志、水口裕之
- Organizer
  第67回生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 薬物動態学的応用のためのヒト腸管オルガノイド培養法の比較2021
- Author(s)
  横田純平、山下智起、乾達也、野元隆我、川上賢太郎、岸本航、仲瀬裕志、水口裕之
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 多発性骨髄腫における新規エピジェネティック免疫療法の開発．2021
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓．
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] Establishment of MDR1-knockout human intestinal organoids for pharmaceutical application2021
- Author(s)
  Jumpei Yokota, Ryuga Nomoto, Tatsuya Inui, Tomoki Yamashita, Kentaro Okada, Wataru Kishimoto, Hiroshi Nakase, Hiroyuki Mizuguchi
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 炎症性腸疾患の鑑別診断としてのMEFV遺伝子関連腸炎．2020
- Author(s)
  仲瀬裕志
- Organizer
  第3回日本免疫不全自己炎症学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] JAPAN IBD COVID-19 Taskforceの現在、そして今後の課題2020
- Author(s)
  仲瀬裕志．
- Organizer
  第11回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] いつ知るの？今でしょ！IBDとCOVID－19(JSIBD MS教育セミナー)2020
- Author(s)
  仲瀬裕志
- Organizer
  第11回炎症性腸疾患学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 慢性胃炎および胃がんに関連する長鎖non-coding RNAの同定2020
- Author(s)
  北嶋洋志、丸山玲緒、高澤啓、新沼猛、山本英一郎、甲斐正広、時野隆至、小山内誠、仲瀬裕志、鈴木拓
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] Single-cell analyses unravel unique features of plasma cell clones in POEMS syndrome2020
- Author(s)
  Yusuke Isshiki, Naoya Mimura, Motohiko Oshima, Kensuke Kayamori, Masahide Seki, Yurie Nagai, Shokichi Tsukamoto, Yusuke Takeda, Chikako Ohwada, Sonoko Misawa, Junichiro Ikeda, Satoshi Kuwabara, Yutaka Suzuki, Emiko Sakaida, Chiaki Nakaseko, Atsushi Iwama
- Organizer
  米国血液学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] Japan IBD COVID-19 Taskforce の現在、そして今後の課題　Panel discussion 3. COVID-19 パンデミック下でのIBD診療2020
- Author(s)
  仲瀬裕志
- Organizer
  第11回炎症性腸疾患学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] ヒト十二指腸オルガノイドの薬物動態評価系への応用2020
- Author(s)
  乾達也、山下智起、野元隆我、川上賢太郎、高山和雄、岸本航、仲瀬裕志、水口裕之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] Single plasma cell transcriptome analysis in POEMS syndrome2020
- Author(s)
  Yusuke Isshiki, Naoya Mimura, Motohiko Oshima, Kensuke Kayamori, Masahide Seki, Kiyomi Imamura, Terumi Horiuchi, Yurie Nagai, Shokichi Tsukamoto, Yusuke Takeda, Chikako Ohwada, Sonoko Misawa, Satoshi Kuwabara, Yutaka Suzuki, Emiko Sakaida, Chiaki Nakaseko, Atsushi Iwama
- Organizer
  Annual Meeting of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] 今しっておきたいIBDと感染症 (JSIBD教育セミナー)2020
- Author(s)
  仲瀬裕志
- Organizer
  第11回炎症性腸疾患学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] The treatment goal of Crohn’s disease based on the new therapeutic strategy．2020
- Author(s)
  仲瀬裕志．
- Organizer
  第62回日本消化器病学会大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] Single cell RNA analysis of plasma cells in POEMS syndrome2020
- Author(s)
  Naoya Mimura, Yusuke Isshiki, Motohiko Oshima, Kensuke Kayamori, Masahide Seki, Kiyomi Imamura, Terumi Horiuchi4, Emiko Sakaida, Chiaki Nakaseko, Yutaka Suzuki4, Atsushi Iwama
- Organizer
  日本骨髄腫学会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] 多発性骨髄腫における新規エピジェネティック併用療法の開発2020
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 慢性胃炎および胃がんに関連する長鎖non-coding RNAの同定2020
- Author(s)
  北嶋洋志、丸山玲緒、高澤啓、新沼猛、山本英一郎、甲斐正広、時野隆至、小山内誠、仲瀬裕志、鈴木拓
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] ECCO-AOCC Forum 2020 :Optimal strategies for drug therapy: Which one, when, and how?2020
- Author(s)
  Hiroshi Nakase
- Organizer
  Asian Organization for Crohn’s and Colitis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] EZH2とG9aの共阻害はインターフェロンシグナルの活性化とIRF-4-MYCaxisの抑制により多発性骨髄腫細胞の増殖を抑制する2020
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，山本英一郎，甲斐正広，仲瀬裕志，鈴木拓
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 北海道内のIBD患者におけるIFX-BS治療のReal world data～Phoenix cohortより～2020
- Author(s)
  風間友江，横山佳浩，平山大輔，我妻康平，安藤勝祥，上野伸展，藤谷幹浩，伊藤貴博，前本篤男，仲瀬裕志．
- Organizer
  第11回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 炎症性腸疾患治療―過去・現在・そして未来―2019
- Author(s)
  仲瀬裕志
- Organizer
  第15回日本消化管学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 我が国におけるIBDの動向と治療の最前線．2019
- Author(s)
  仲瀬裕志
- Organizer
  JDDW 2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] Role of biosimilars in IBD : What you need to know now2019
- Author(s)
  仲瀬裕志
- Organizer
  第61回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] Novel therapies targeting several immune pathways for ulcerative colitis.2019
- Author(s)
  仲瀬裕志
- Organizer
  第118回日本消化器内視鏡学会北海道支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 炎症性腸疾患鑑別診断としての家族性地中海熱遺伝子関連腸炎2019
- Author(s)
  仲瀬裕志
- Organizer
  第47回日本臨床免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling.2019
- Author(s)
  Ishiguro K, Kitajima H, Niinuma T, Ishida T, Maruyama R, Ikeda H, Yamamoto E, Kai M, Sasaki Y, Tokino T, Nakase H, Suzuki H.
- Organizer
  11th AACR-JCA Joint International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] Can TDM guide us to de-escalate?2019
- Author(s)
  Nakase H.
- Organizer
  The 7th Annual Meeting of Asian Organization for Crohn’s & Colitis.
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 多発性骨髄腫における新規エピジェネティック併用療法の開発2019
- Author(s)
  石黒一也，北嶋洋志，新沼猛，石田禎夫，丸山玲緒，池田博，山本英一郎，甲斐正広，佐々木泰史，時野隆至，仲瀬裕志，鈴木拓
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 炎症性大腸発癌の深部浸潤機序における低分子量GTP蛋白質Ralの機能解析2019
- Author(s)
  飯田智哉，川上賢太郎，仲瀬裕志
- Organizer
  第15回日本消化管学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] Can TDM guide us to de-escalate?2019
- Author(s)
  Nakase H.
- Organizer
  The 7th Annual Meeting of Asian Organization for Crohn’s & Colitis.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] The involvement of cytomegalovirus in the pathophysiology of inflammatory bowel disease．2019
- Author(s)
  仲瀬裕志
- Organizer
  第105回日本消化器病学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 多発性骨髄腫に対するDOT1L阻害の抗腫瘍効果の解析2019
- Author(s)
  石黒一也，北嶋洋志，新沼猛，丸山玲緒，池田博，石田禎夫，山本英一郎，甲斐正広，佐々木泰史，時野隆至，仲瀬裕志，鈴木拓
- Organizer
  第120回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03518
[Presentation] 炎症性腸疾患治療―過去・現在・そして未来―2019
- Author(s)
  仲瀬裕志
- Organizer
  第15回日本消化管学会総会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] ヒト十二指腸オルガノイドの樹立と薬物動態評価系への応用2019
- Author(s)
  乾達也、山下智起、野元隆我、川上賢太郎、高山和雄、岸本航、仲瀬裕志、水口裕之
- Organizer
  第69 回日本薬学会関西支部総会・大会
- Data Source
  KAKENHI-PROJECT-20K20381
[Presentation] 炎症性腸疾患領域における生物学的製剤の位置付け．2018
- Author(s)
  仲瀬裕志．
- Organizer
  第46回日本臨床免疫学会総会．
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 病態ならびに粘膜治癒の新規評価システムに基づいた潰瘍性大腸炎の治療戦略．2018
- Author(s)
  仲瀬裕志
- Organizer
  第95回日本消化器内視鏡学会総会．
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] Understanding current treatment of ulcerative colitis based on mode of action．2018
- Author(s)
  仲瀬裕志
- Organizer
  第55回日本消化器免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] Ral-NLRP3インフラマソーム経路は炎症性大腸発癌を促進する．2018
- Author(s)
  飯田智哉，野島正寛，堀内久徳，仲瀬裕志．
- Organizer
  第77回日本癌学会学術総会．
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] Therapeutic efficacy and adverse events of tacrolimus in patients with Crohn’s disease : a systematic review and meta-analysis.2018
- Author(s)
  Iida T, Nojima M, Nakase H.
- Organizer
  Digestive Disease Week2018．
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 潰瘍性大腸炎新規内視鏡粘膜評価法を目指したReal-time automated calculating systemの開発．2018
- Author(s)
  仲瀬裕志，Peter B，Raf B．
- Organizer
  JDDW 2018
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 炎症性腸疾患に合併する肺病変の発症機序―免疫学的観点からのアプローチ―．2018
- Author(s)
  仲瀬裕志．
- Organizer
  第95回日本消化器内視鏡学会総会．
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] Positioning of Golimumab in UC treatment based on immunogenicity to biologics2018
- Author(s)
  仲瀬裕志
- Organizer
  第204回日本消化器病学会東北支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] Understanding current treatment of ulcerative colitis based on mode of action．2018
- Author(s)
  仲瀬裕志．
- Organizer
  第55回日本消化器免疫学会総会．
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 炎症性腸疾患領域における生物学的製剤の位置付け2018
- Author(s)
  仲瀬裕志
- Organizer
  第46回日本臨床免疫学会総会．
- Invited
- Data Source
  KAKENHI-PROJECT-18H02799
[Presentation] 潰瘍性大腸炎の最適治療を模索する―ブデソニド注腸フォーム剤の可能性を含めて―．2018
- Author(s)
  仲瀬裕志．
- Organizer
  第14回日本消化管学会総会学術集会．
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 潰瘍性大腸炎新規内視鏡粘膜評価法を目指したReal-time automated calculating systemの開発．2018
- Author(s)
  仲瀬裕志，Peter B，Raf B．
- Organizer
  第60回日本消化器病学会大会．
- Invited
- Data Source
  KAKENHI-PROJECT-18K07947
[Presentation] 口腔扁平上皮癌の全エクソン解析2017
- Author(s)
  佐々木泰史, 田村みゆき, 中垣貴文, 小山良太, 井戸川雅史, 荻和弘, 平塚博義, 仲瀬裕志, 時野隆至
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06279
[Presentation] パーソナルゲノム解析を通じた日本人クローン病感受性遺伝子の探索2016
- Author(s)
  小野寺馨, 有村佳昭, 榮浪洋介, 横山佳浩, 山本至, 一色裕之, 川上賢太郎, 久保俊之, 山下健太郎, 仲瀬裕志
- Organizer
  第24回日本消化器関連学会週間（JDDW）
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K09317
[Presentation] パーソナルゲノム解析を通じた日本人クローン病感受性遺伝子の探索2016
- Author(s)
  小野寺馨, 有村佳昭, 榮浪洋介, 横山佳浩, 山本至, 一色裕之, 川上賢太郎, 久保俊之, 山下健太郎, 仲瀬裕志
- Organizer
  JDDW 2016
- Place of Presentation
  神戸国際展示場（兵庫県，神戸市）
- Data Source
  KAKENHI-PROJECT-15K08972
[Presentation] ラットマクロファージ免疫機構におけるS100A8及びS100A9のオートクライン的制御経路の可能性に関する研究2016
- Author(s)
  岡田光貴，荒井智，戸田好信，竹田真由，仲瀬裕志，池本正生
- Organizer
  第54回日本臨床化学会年次学術集会
- Place of Presentation
  東京大学本郷キャンパス
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] ラット大腸3次元培養における間葉系幹細胞のニッチ作用2016
- Author(s)
  川上賢太郎，一色裕之，有村佳昭，小野寺馨，永石歓和，山下健太郎，藤宮峯子，仲瀬裕志
- Organizer
  JDDW 2016
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-26460975
[Presentation] CD68を介したS100A8及びS100A9によるマクロファージ活性化機構に関する研究2016
- Author(s)
  岡田光貴，荒井智，戸田好信，竹田真由，仲瀬裕志，池本正生
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-11-22
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] CD68 on rat macrophages binds tightly to S100A8 and S100A9, and subsequently helps to regulate the cell’s immune functions2016
- Author(s)
  Okada K, Arai S, Itoh H, Adachi S, Nakase H, and Ikemoto M
- Organizer
  21st IFCC-EFLM European Concress of Clinical Chemistry and Laboratory Medicine
- Place of Presentation
  Paris Maillot, France
- Year and Date
  2016-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] ラット大腸3次元培養における間葉系幹細胞のニッチ作用2016
- Author(s)
  川上賢太郎, 一色裕之, 有村佳昭, 小野寺馨, 永石歓和, 山下健太郎, 藤宮峯子, 仲瀬裕志
- Organizer
  JDDW 2016
- Place of Presentation
  神戸国際展示場（兵庫県，神戸市）
- Data Source
  KAKENHI-PROJECT-15K08972
[Presentation] パーソナルゲノム解析を通じた日本人クローン病感受性遺伝子の探索2016
- Author(s)
  小野寺馨，有村佳昭，榮浪洋介，横山佳浩，山本至，一色裕之，川上賢太郎，久保俊之，山下健太郎，仲瀬裕志
- Organizer
  JDDW 2016
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-26460975
[Presentation] S100A8及びS100A9を指標とした潰瘍性大腸炎発症メカニズムの解析に関する研究2016
- Author(s)
  岡田光貴，荒井智，戸田好信，竹田真由，仲瀬裕志，池本正生
- Organizer
  第53回日本臨床化学会年次学術集会
- Place of Presentation
  あわぎんホール
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] CD68 on rat macrophages binds tightly to S100A8 and S100A9, and subsequently helps to regulate the cell’s immune functions2015
- Author(s)
  Okada K, Arai S, Itoh H, Adachi S, Nakase H, and Ikemoto M
- Organizer
  21st IFCC-EFLM European Concress of Clinical Chemistry and Laboratory Medicine
- Place of Presentation
  France, Paris (Palais des Congres)
- Year and Date
  2015-06-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] ここまでわかってきた炎症性腸疾患―現在そしてこれからの課題―急激に増えている腸の病気　潰瘍性大腸炎クローン病2014
- Author(s)
  仲瀬裕志
- Organizer
  埼玉市民公開講座
- Place of Presentation
  埼玉
- Year and Date
  2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] Use of Tacrolimus and Infliximab for refractory ulcerative colitis2012
- Author(s)
  Nakase H
- Organizer
  The 6th Korea-Japan inflammatory bowel disease Symposium
- Place of Presentation
  東京
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] IL-17 promotes HSP47 expression and intestinal fibrosis in Crohn's disease2011
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Uza N, Matsuura M, Chiba T
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2011-05-08
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Characteristics of colonoscopic features in patients with ulcerative colitis concomitant with cytomegalovirus reactivation2011
- Author(s)
  Matsuura M, Nakase H, Honzawa Y, Yamamoto S, Matsumura K, Uza N, Chiba T
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2011-05-09
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Role of osteopontin in acute graft-versus-host disease.2010
- Author(s)
  Takeda Y, Nakase H, Honzawa Y, Matsumura K, Yamamoto S, Yoshino T, Uza N, Ueno S, Chiba T.
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, 米国
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] 重症潰瘍性大腸炎にたいするタクロリムスによる寛解導入療法の短期および長期成績の検討2010
- Author(s)
  山本修司, 仲瀬裕志, 千葉勉
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Novel immunomodulating effect of tacrolimus : induction of apoptosis on macrophage attenuates immune-mediated colitis2010
- Author(s)
  Yoshino T, Nakase H, Chiba T
- Organizer
  DDW
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-03
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Use of tacrolimus in in flammatory bowel disease2010
- Author(s)
  Nakase H
- Organizer
  The 4th Korea-Japan Inflammatory bowel disease Symposium Japan
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] クローン病に対する内視鏡的拡張術と免疫調節剤との併用における長期予後の検討2010
- Author(s)
  本澤有介, 仲瀬裕志, 千葉勉
- Organizer
  第96回日本消化器病学会総会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Role of Heat shock protein 47 in the pathogenesis of patients with Crohn's disease2010
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Uza N, Chiba T
- Organizer
  DDW
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Serum level of heat shock protein 47 could be a useful marker for intestinal fibrosis in patients with Crohn's disease2010
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Uza N, Matsuura M, Chiba T
- Organizer
  Gut
- Place of Presentation
  UEGW, Barcelona
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] CMV再活性化を有する難治性潰瘍性大腸炎の今後の治療戦略2010
- Author(s)
  松村佳代子, 仲瀬裕志, 千葉勉
- Organizer
  第18回日本消化器関運学会週間
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Overview:炎症性腸疾患(IBD)の病態と免疫調節療法2010
- Author(s)
  仲瀬裕志, 千葉勉
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Novel immunomodulating effect of tacrolimus : induction of apoptosis on macrophage attenuates immune-mediated colitis.2010
- Author(s)
  Yoshino T, Nakase H, Chiba T.
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, 米国
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] インフリキマブの難治性潰瘍性大腸炎に対する治療効果の検討2010
- Author(s)
  本澤有介, 仲瀬裕志, 千葉勉
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Role of osteopontin in acute graft-versus-host disease2010
- Author(s)
  Takeda Y, Nakase H, Honzawa Y, Matsumura K, Yamamoto S, Yoshino T, Uza N, Ueno S, Chiba T
- Organizer
  DDW
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-02
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Hes1は腸腫瘍の増殖や未分化性の維持に重要である2010
- Author(s)
  上尾太郎, 妹尾浩, 仲瀬裕志
- Organizer
  第18回日本消化器関連学会週間
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Measurement of serum diamine oxidase(DAO) activity can be a predictive factor of disease onset of human IBD2010
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Uza N, Chiba T
- Organizer
  DDW
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Role of Heat shock protein 47 in the pathogenesis of patients with Crohn's disease.2010
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Uza N, Chiba T.
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, 米国
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Measurement of serum diamine oxidase (DAO) activity can be a predictive factor of disease onset of human IBD.2010
- Author(s)
  Honzawa Y, Nakase H, Matsumura K, Yamamoto S, Yoshino T, Takeda Y, Ueno S, Uza N, Chiba T.
- Organizer
  Digestive Disease Week
- Place of Presentation
  New Orleans, 米国
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] 潰瘍性大腸炎における効果的な治療選択2009
- Author(s)
  仲瀬裕志
- Organizer
  第51回日本消化器病学会大会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Regulation of activate macrophages by FK506 attenuates immune-mediated colitis2009
- Author(s)
  Yoshino T, Nakase H, Matsumura K, Yamamoto S, Takeda Y, Ueno S, Uza N, Chiba T
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] The Critical role of CXC chemokine ligand 16/scavenger receptor in the pathogenesis of inflammatory bowel disease2009
- Author(s)
  Uza N, Nakase H, Chiba T
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2009-05-31
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Suppression of LPS-induced NF-kB and p38MAPK activation by FK506 ameliorates murine colitis2009
- Author(s)
  Yoshino T, Nakase H, Matsumura K, Yamamoto S, Takeda Y, Ueno S, Uza N, Chiba T
- Organizer
  14th international congress of mucosal immunology
- Place of Presentation
  Boston
- Year and Date
  2009-07-05
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] Acitvation of Innate immune response by osteopontine prevent onset of spontaneous colitis2009
- Author(s)
  Ueno S, Nakase H, Chiba T
- Organizer
  DDW
- Place of Presentation
  Chicago
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21590810
[Presentation] The critical involvement of cytomegalovirus infection in inflammatory bowel disease refractory to conventional therapies-How to diagnose at early stage?2007
- Author(s)
  Nakase H
- Organizer
  The 3rd Annual meeting of the Japanese Gastroenterological Association
- Place of Presentation
  東京
- Year and Date
  2007-02-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] The Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus in patients with UC refractory to immunosuppressive therapies2007
- Author(s)
  Nakase, H, et. al.
- Organizer
  UEGW
- Place of Presentation
  France
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Bifidobacterium logum(BB536) therapy shifts cytokine profile toward T-helper 1 by up-regulation of T-bet and enhances mucosal barrier function2007
- Author(s)
  Inoue, S, Nakase, H, et. al.
- Organizer
  13th ICMI
- Place of Presentation
  Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] The Usefulness of quantitative real -time PCR assay for early detection of cytomegalovirus in patients with UC refractory to immunosuppressive therapies2007
- Author(s)
  Yoshino, T, Nakase, H, et. al.
- Organizer
  13th ICMI
- Place of Presentation
  Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] The Critical role of Heat Shock Protein 47 in intestinal Fibrosis associated with inflammatory bowel disease2007
- Author(s)
  Kitamura, H, Nakase, H, et. al.
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Rescue therapy with leukocytapheresis for patients with ulcerative colitis refractory to immunomodulators by alternation of CXCR4 expression on T cells and Thl/Th2 balance2007
- Author(s)
  Nakase, H, et. al.
- Organizer
  UEGW
- Place of Presentation
  France
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] The Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus in patients with UC refractory to immunosuppressive therapies2007
- Author(s)
  Yoshino, T, Nakase, H, et. al.
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Modulation of Heat shock protein 47 in intestinal fibrosis of inflammatory bowel disease regulated by interleukin-102007
- Author(s)
  Kitamura, H, Nakase, H, et. al.
- Organizer
  13th ICMI
- Place of Presentation
  Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Ectopic expression of activation-induced cytidine deaminase in ulcerative colitis-associated colorectal cancers2007
- Author(s)
  Kou, T, Marusawa, H, Endo, Y, Nakase, H, et. al.
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Critical role of CXCL12-CXCR4 interaction in the pathophysiology of inflammatory bowel disease2006
- Author(s)
  Mikami, S, Nakase, H, Nagasawa, T, Chiba, T
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Basic fibroblast growth factor-induced multidrug resistance 1 expression plays an important role in the protective effect on intestinal epithelial injury2006
- Author(s)
  Matsuura, M, Nakase, H, Masuda, S, Tabata, Y, Chiba, T
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Maintenance therapy with tacrolimus in patients with Crohn's disease refractory to Azathiopurine : 2 year trial2006
- Author(s)
  Nakase, H, et. al.
- Organizer
  Digestive Disease Week
- Place of Presentation
  USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] Novel maintenance therapy with tacrolimus in patients with Crohn's disease refractory to Azathioprine2006
- Author(s)
  Nakase, H, et. al.
- Organizer
  UEGW
- Place of Presentation
  Germany
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590677
[Presentation] CD68を介したS100A8及びS100A9によるマクロファージ活性化機構に関する研究
- Author(s)
  岡田光貴, 荒井智, 戸田好信, 竹田真由, 仲瀬裕志, 池本正生
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-11-22 – 2014-11-25
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] Asian Forum 1. The Current Status of IBD Care in Asia. Treatment of IBD in Asia
- Author(s)
  Nakase H
- Organizer
  The 2nd Annual meeting of AOCC
- Place of Presentation
  Korea
- Year and Date
  2014-06-19 – 2014-06-21
- Invited
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] 炎症性腸疾患における栄養管理の重要性
- Author(s)
  仲瀬　裕志
- Organizer
  第17回日本病態栄養学会年次学術集会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] nvolvement of IL-34 in intestinal inflammation of Crohn’s disease
- Author(s)
  Yoshino T, Matsuura M, Nakase H
- Organizer
  The 2nd Annual meeting of AOCC
- Place of Presentation
  Korea
- Year and Date
  2014-06-19 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] IFX治療後の難治性潰瘍性大腸炎の長期経過
- Author(s)
  仲瀬　裕志
- Organizer
  第85回日本消化器内視鏡学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] Efficacy of Probiotic treatment with bifidobacterium longum 536 for induction of remission in active ulcerative colitis : a randomized multicenter trial.
- Author(s)
  Tamaki H, Nakase H, Shibatoge M.
- Organizer
  The 2nd Annual meeting of AOCC.
- Place of Presentation
  Korea
- Year and Date
  2014-06-19 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] 炎症性腸疾患治療と今後の課題
- Author(s)
  仲瀬　裕志
- Organizer
  日本内科学会東海支部　第53回生涯教育講演会
- Place of Presentation
  浜松（アクトシティ浜松コングレスセンター）
- Invited
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] ラットマクロファージ免疫機能におけるS100A8及びS100A9のオートクライン的制御経路の可能性に関する研究
- Author(s)
  岡田光貴, 荒井智, 竹田真由, 戸田好信, 仲瀬裕志, 池本正生
- Organizer
  第54回日本臨床化学会年会
- Place of Presentation
  東京大学本郷キャンパス
- Year and Date
  2014-09-05 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26460663
[Presentation] Short and long-term outcome of severe ulcerative colitis patients treated with tacrolimus and infliximab
- Author(s)
  Minami N, Yoshino T, Matsuura M, Nakase H
- Organizer
  Digestive Disease Week 2014
- Place of Presentation
  USA
- Year and Date
  2014-05-02 – 2014-05-06
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] 粘膜治癒を目指した潰瘍性大腸炎に対する治療法―ステロイドフリーの時代へー
- Author(s)
  仲瀬　裕志
- Organizer
  第114回日本消化器病学会北陸支部例会　第２７回教育講演会
- Place of Presentation
  福井（福井県民ホール）
- Invited
- Data Source
  KAKENHI-PROJECT-24590941
[Presentation] 難治性炎症性腸疾患に対する今後の治療
- Author(s)
  仲瀬　裕志
- Organizer
  第98回日本消化器病学会近畿支部例会　第41回教育講演会
- Place of Presentation
  神戸（神戸ポートピアホテル）
- Invited
- Data Source
  KAKENHI-PROJECT-24590941

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Nakase Hiroshi 仲瀬 裕志

NAKASE Hiroshi 仲瀬 裕志

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Elucidation of Inflammatory Bowel Disease Pathophysiology by Application of Organoid-iPS Cell SystemPrincipal Investigator

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Development of personalized medcicine for inflammatory bowel disease based on control of epigenomePrincipal Investigator

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Nakase Hiroshi 仲瀬裕志

NAKASE Hiroshi 仲瀬裕志

[Book] 内科学書改訂第９版 Vol.4．腸結核.2019

[Book] 内科学書改訂第９版 Vol.4．膠原病の消化管病変．2019

[Book] 内科学書改訂第９版 Vol.4．腸管（型）Bechet病と単純性潰瘍2019

[Book] 最適治療を極める！クローン病2019