HAYAKAWA Hiroshi 早川浩

Researcher Number	70150422
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 福岡歯科大学, 口腔歯学部, 教授 2006 – 2015: Fukuoka Dental College, Department of Biochemistry, Professor, 歯学部, 教授 2013: 福岡歯科大学, 口腔歯学部, 教授 2004 – 2005: 九州大学, 大学院・医学研究院, 助手 2001 – 2002: 九州大学, 医学研究院, 助手 … More 2000: KYUSHU UNIVERSITY, Faculty of Medical Sciences, Research Associate, 大学院・医学研究院, 助手 1998 – 2000: Graduate school of Medical Sciences, Kyushu University, Assistant Professor, 大学院・医学系研究科, 助手 1988 – 1999: 九州大学, 医学部, 助手 1992: 九州大学, 医学部, 助教 Less
Review Section/Research Field	Principal Investigator 環境影響評価(含放射線生物学) / 放射線5生物学 / Genetics/Chromosome dynamics / Molecular biology / Molecular biology / Biological Sciences Except Principal Investigator Molecular biology / Molecular biology / Genetics/Genome dynamics / Risk sciences of radiation/Chemicals … More / 環境影響評価(含放射線生物学) / Risk sciences of radiation and chemicals / Surgical dentistry / Functional biochemistry / 放射線5生物学 Less
Keywords	Principal Investigator 酸化ストレス / 突然変異 / DNA修復 / RNA結合蛋白 / 転写エラー / 異常蛋白 / 品質管理 / 老化 / ヌクレオチド代謝 / 酸化ヌクレオチド … More / 活性酸素 / RNA binding protein / Oxidative stress / 異常タンパク / Quality Control / RNA結合因子 / 転写 / 複製 / DNA複製 / クローニング / アルキル化剤 / cDNA / 癌 / 遺伝子 / 網羅的 / Aging / Abnormal protein / Transcriptonal error / Erroneous protein / Transcriptional error / 酸化損傷 / 品質管理機構 / RNA品質管理 / 質量分析 / DNA修復・損傷 / 核酸損傷 / RNA / アルツハイマー病 / fidelity / エラー / ヌクレオチド / 浄化 / ミューテーター / DNA損傷 / ヌクレオチドプール / mutagenesis / ヒト / DNA障害 / 発現ベクター / 化学発癌 / 遺伝子クロ-ニング / DNA修復酵素 / Mer形質 / cDNAクロ-ニング / メチルトランスフェラ-ゼ / 遺伝病 / 発現ベクタ- / クロ-ニング … More Except Principal Investigator 突然変異 / DNA修復 / DNA修復酵素 / 酸化ストレス / 活性酸素 / DNA repair / 標的遺伝子組換え / 発がん / 8-オキソグアニン / 変異マウス / ジーン・ターゲティング / 胚性幹細胞(ES細胞) / 遺伝情報 / RNA / Mutation / アルキル化剤 / 酸化RNA / アポトーシス / 相同的組換え / DNA損傷 / oxidative stress / mouse / gene cloning / mutation / マウス / 活性酵素 / 2-OH-dATP / 8-oxo-guanine / Carcinogenesis / Oxidative stress / Reactive oxygen / ミューテーター / 8-oxo-dGTPase / gene targeting / alkylating agent / 遺伝子ターゲティング / 遺伝子 / メチルトランスフェラ-ゼ / 転写調節 / Auf1 / 癌抑制遺伝子 / 大腸菌 / アルキル塩基高感度検出法 / 選択的化学療法 / 抗ヒトMGMT抗体 / Mer^-細胞 / O^6-アルキルグアニン / モノクローナル抗体 / 疾患 / AUF1 / mRNA分解 / mRNA / 8-oxoG / 酸化損傷 / 老化 / 神経変性疾患 / PCBP1 / ８－オキソグアニン / methyltransferase / induced mutation / spontaneous mutation / DNA polymerase / replication fidelity / DNAポリメラーゼ / 発がんの抑制 / 遺伝子のクローニング / アルキル科剤 / メチルトランスフェラーゼ / DNA複製 / 誘導突然変異 / 自然突然変異 / 遺伝子クロ-ニング / DNAポリメラ-ゼ / 複製精度 / expression / genetic information / quality control / ribonucleotide / oxidized guanine / 発現 / 品質管理 / リボヌクレオチド / 酸化グアニン / reactive oxygen species / mutagenesis / radiation / genome / environment / nucleic acids / gene / 細胞死 / 酸化的RNA損傷 / 変異スペクトラム / 酸化的DNA損傷 / 放射線 / ゲノム / 環境 / 核酸 / E.coli / oxidized RNA / cancer / active oxygen / 細胞株 / 遺伝子クローニング / Tumor suppressor gene / 神経細胞死 / β-オキソグアニン / 2ーOH-dATP / DNA修飾 / 8ーオキソグアニン / Mutator / 8-oxo-dGTP / O^6-methylguanine / repair methyltransferase / gene-defective mouse / monoclonal antibody / modified base / O^6-メチルグアニン / 修復メチルトランスフェラーゼ / 遺伝子欠損マウス / 修復塩基 / Targeting Vector / Plasmid / lambda Phage / Homologous Recombination / Gene Targeting / Targeted Mutagenesis / ネガティブ選択 / ターゲティングベクター / プラスミド / λファージ / 相同組換え / ジーンターゲティング / DNA binding protein / DNA damages / protein structure / 結晶化 / 分子生物学 / 修復酵素 / DNA結合蛋白質 / 蛋白質の構造 / Adaptive Response / Alkylating Agent / Ada Regulon / Gene Expression / Transcriptional Control / DNA Damage / DNA Repair Enzyme / DNA修復酸素 / 抗がん剤 / 突然変異の誘起 / 適応応答 / adaレギュロン / 遺伝子発現 / Mth1 / mutT / RNAの分解 / ノックアウト細胞株 / ヌクレオチド代謝 / 酸化ヌクレオチド / ８ーオキソグアニン / RNA 酸化 / TRP / EMT / 老化マーカー / エピジェネティック修飾 / 細胞老化 / ケラチノサイト / 口腔癌 / EBウィルス / DNAトポイソメラーゼ / DNAトポロジー / DNAの超らせん構造 / ストレス / クロロキン / プラスミドDNA / ES細胞 / 遺伝子ノックアウトマウス / 分子シャペロン / DNAジャイレース / DnaK / 熱ショックタンパク / ストレス刺激 / DNAの超らせん / 相同定組換え / H-ras遺伝子 / MGMT遺伝子の発現制御機構 / メチル転移酵素(MGMT) / ヒトMGMT遺伝子 / アルキル転移酵素(MGMT) / 染色体地図 / ファンコニ-貧血症 / 遺伝病 / 色素性乾皮症 / トランスフォーミング遺伝子 / cDNA発現 / ras遺伝子カスケード / cーRAF蛋白 Less

Research for mechanisms of control in gene expression under oxidative stress
- Principal Investigator
  
  Ishii Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
活性酸素により生じた変異誘発物質の排除機構Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Fukuoka Dental College
Cell death mechanism by RNA oxidative signal transduction
- Principal Investigator
  
  Sekiguchi Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University
A study on the response of oral mucosa to reactive oxygen species and its application to the prevention against oral cancer.
- Principal Investigator
  
  IKEBE Tetsuro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Fukuoka Dental College
RNA damages and RNA quality controlPrincipal Investigator
- Principal Investigator
  
  HAYAKAWA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Mechanisms for quality control of RNA in mammalian cells
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Fukuoka Dental College
Establishment of a sensitive assay system for detecting mutations induced by oxidative DNA damage
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  KYUSHU UNIVERCITY
AD患者の脳神経細胞に蓄積する酸化RNAに結合する蛋白のcDNAクローニングPrincipal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Quality Control of mRNAPrincipal Investigator
- Principal Investigator
  
  HAYAKAWA Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Elimination of Oxidized Guanine Ribonucleotides in Mammalian CellsPrincipal Investigator
- Principal Investigator
  
  HAYAKAWA Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYUSHU UNIVERSITY
Regulatory mechanisms for mutagenesis and carcinogenesis
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Oxygen-induced DNA damage and its repair mechamism
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Molecular biology
- Research Institution
  KYUSHU UNIVERSITY
哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Repair of alkylation DNA damage
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Molecular mechanism for suppressing oxidative DNA damage
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  KYUSHU UNIVERSITY
酸化およびアルキル化DNA損傷を防ぐヒト酵素の精製と解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyushu University
ストレス誘導性のDNAトポロジー変化のヒト細胞での解析
- Principal Investigator
  
  関水和久
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyushu University
Development of an Effecient System for Gene Targeting
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
標的遺伝子組換えによるミューテーター(高突然変異)マウスの作製とその発癌への影響
- Principal Investigator
  
  續輝久
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
活性酸素によるDNA障害を防ぐヒト蛋白の分離と解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyushu University
標的遺伝子組換えによるミューテーター(高突然変異)マウスの作製とその発癌への影響
- Principal Investigator
  
  續輝久
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
標的遺伝子組換えによるDNA修復酵素遺伝子の機能の解析
- Principal Investigator
  
  續輝久
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
ヒトにおけるDNA修復機構の解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  環境影響評価(含放射線生物学)
- Research Institution
  Kyushu University
標的遺伝子組換えによるDNA修復酵素遺伝子の機能の解析
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kyushu University
Structure and function of DNA repair enzymes
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
真核生物の遺伝情報維持の分子機構とその制御
- Principal Investigator
  
  武部啓
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  放射線5生物学
- Research Institution
  Kyoto University
ヒトDNA修復酵素cDNAのクローニングPrincipal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  放射線5生物学
- Research Institution
  Kyushu University
cDNA発現ベクタ-を用いた高発癌性遺伝病の遺伝子クロ-ニングと解析Principal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
O^6-アルキルグアニン-アルキル転移酵素の制がんと発がんにおける役割
- Principal Investigator
  
  池永満生
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
O^6-アルキルグアニン-アルキル転移酵素の制がんと発がんにおける役割
- Principal Investigator
  
  池永満生
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
新しいcDNA発現ベクタ-を用いた遺伝病における欠損遺伝子のクロ-ニングPrincipal Investigator
- Principal Investigator
  
  早川浩
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  放射線5生物学
- Research Institution
  Kyushu University
Molecular mechanisms of the adaptive response to alkylating agents
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYUSHU UNIVERSITY
がん遺伝子産物の機能とそのカスケードの解析
- Principal Investigator
  
  SHIMIZU Kenji
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
高発がん性遺伝病の遺伝子解析
- Principal Investigator
  
  武部啓
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto University
Maintenance of Genetic Information and Mutagenesis Mechanisms
- Principal Investigator
  
  SEKIGUCHI Mutsuo
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyushu University

All 2018 2017 2016 2015 2010 2009 2007 2006 Other

All Journal Article Presentation

[Journal Article] Specific binding of PCBP1 to heavily oxidized RNA to induce cell death2018
- Author(s)
  Ishii Takashi、Hayakawa Hiroshi、Igawa Tatsuhiro、Sekiguchi Takeshi、Sekiguchi Mutsuo
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 26 Pages: 6715-6720
- DOI
  10.1073/pnas.1806912115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07260
[Journal Article] Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.2015
- Author(s)
  Ishii T, Hayakawa H, Sekiguchi T, Adachi N, Sekiguchi M.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 79 Pages: 109-116
- DOI
  10.1016/j.freeradbiomed.2014.11.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24570160, KAKENHI-PROJECT-26340040, KAKENHI-PROJECT-26670031
[Journal Article] Human Proteins that Specifically Bind to 8-Oxoguanine-containing RNA and their Responses to Oxidative Stress.2010
- Author(s)
  Hiroshi Hayakawa, Aya Fujikane, Riyoko Ito, Masaki Matsumoto, Keiichi I.Nakayama, Mutsuo Sekiguchi
- Journal Title
  
  Biochemical and Biophysical Research Communications 403
  
  Pages: 220-224
- Data Source
  KAKENHI-PROJECT-20570168
[Journal Article] Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress2010
- Author(s)
  Hiroshi Hayakawa, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 403 Pages: 220-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570168
[Journal Article] Human polynucleotide phosphorylase protein in response to oxidative stress.2006
- Author(s)
  Hayakawa, H, Sekiguchi, M
- Journal Title
  
  Biochemistry 45・21
  
  Pages: 6749-6755
- Data Source
  KAKENHI-PROJECT-16310043
[Journal Article] Human polynucleotide phosphorylase protein in response to oxidative stress.2006
- Author(s)
  Hayakawa, H., Sekiguchi, M.
- Journal Title
  
  Biochemistry 45
  
  Pages: 6749-6755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310043
[Journal Article] Human polynucleotide phosphorylase protein in response to oxidative stress.2006
- Author(s)
  Hayakawa, H., Sekiguchi, M.
- Journal Title
  
  Biochemistry 45・21
  
  Pages: 6749-6755
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310043
[Journal Article] Human polynucleotide phosphorylase protein in response to oxidative stress2006
- Author(s)
  Hiroshi Hayakawa
- Journal Title
  
  Biochemistry 45
  
  Pages: 6749-6755
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370005
[Presentation] 酸化損傷を受けたRNA鎖に結合する新規因子の同定2017
- Author(s)
  石井健士、井川達弘、関口猛、早川浩、関口睦夫
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] Human proteins that recognize oxidative RNA damage2017
- Author(s)
  Hayakawa H., Ishii, T., Sekiguchi, M.
- Organizer
  Oxidative Stress & Disease, Gordon Research Conferences (Lucca, Italy)
- Place of Presentation
  Lucca, Italy
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] Human proteins that recognize oxidative RNA damage.2017
- Author(s)
  Hayakawa, H., Ishii, T., Sekiguchi, M.
- Organizer
  Gordon Research Conf. Oxidative Stress and Disease
- Place of Presentation
  Lucca, Italy
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] Human proteins that recognize oxidative RNA damage2017
- Author(s)
  Hiroshi Hayakawa
- Organizer
  "Oxidative Stress & Disease" Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] 酸化損傷mRNAの代謝に関わる新規因子の探索2016
- Author(s)
  石井健士、早川浩、関口猛、関口睦夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-29
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] 酸化ストレスとRNAの品質管理機構2016
- Author(s)
  早川浩
- Organizer
  第88回日本遺伝学会
- Place of Presentation
  三島
- Year and Date
  2016-09-07
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] 酸化損傷mRNAの代謝に関わる新規因子の探索2016
- Author(s)
  石井健士、早川浩、関口猛、関口睦夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 毒性物質の排出における出芽酵母Gtr1タンパク質の働き2016
- Author(s)
  関口猛、石井健士、早川浩、古野伸明、小林英紀、関口睦夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-29
- Data Source
  KAKENHI-PROJECT-16K07453
[Presentation] 毒性物質の排出における出芽酵母Gtr1タンパク質の働き2016
- Author(s)
  関口猛、石井健士、早川浩、古野伸明、小林英紀、関口睦夫
- Organizer
  第39回日本分子生物学会年
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 遺伝子破壊細胞株を用いたヒトNudix ファミリータンパク質の機能解析.2015
- Author(s)
  橋口一成、石井健士、早川浩、関口睦夫.
- Organizer
  第38回日本分子生物学会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 変異原性ヌクレオチドはどこへ行くのか？2015
- Author(s)
  関口睦夫、伊東理世子、関口猛、早川浩、井口八郎
- Organizer
  日本遺伝学会第87回大会
- Place of Presentation
  仙台
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] Human proteins that specifically bind to 8-oxoguanine-containing RNA and their responses to oxidative stress2010
- Author(s)
  Hiroshi Hayakawa, et al.
- Organizer
  第33回日本分子生物学会・第83回日本生化学学会合同大会
- Place of Presentation
  神戸ポートピア
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20570168
[Presentation] Mammalian proteins for eliminating oxidized forms of RNA and its precursors for accurate protein synthesis2009
- Author(s)
  Hiroshi Hayakawa, Riyoko Ito, Mutsuo Sekiguchi
- Organizer
  アメリカ微生物学会(ASM) : The 3^<rd> ASM Conference on DNA Repair and Mutagenesis.(Poster Session)
- Place of Presentation
  カナダ(ウィスラー)
- Data Source
  KAKENHI-PROJECT-20570168
[Presentation] 酸化されたRNAやRNA前駆体を生体から排除し、正確な遺伝情報伝達を保証するヒトのタンパク質群2009
- Author(s)
  早川浩、伊東理世子、関口睦夫
- Organizer
  日本遺伝学会81回大会(ワークショップ)
- Place of Presentation
  長野県松本市信州大学理学部
- Data Source
  KAKENHI-PROJECT-20570168
[Presentation] Mammalian proteins that act on oxidized forms of ribonucleotides and RNA2007
- Author(s)
  Hiroshi Hayakawa
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai, Japan.
- Year and Date
  2007-05-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370005
[Presentation] Mammalian proteins that act on oxidized forms of ribonucleotides and RNA2007
- Author(s)
  Hiroshi Hayakawa
- Organizer
  3rd Japan-US DNA Repair Meeting
- Place of Presentation
  Sendai,Japan
- Year and Date
  2007-05-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18370005
[Presentation] Human Proteins that Specifically Bind to 8-Oxoguanine-containing RNA and their Responses to Oxidative Stress.
- Author(s)
  Hiroshi Hayakawa, Aya Fujikane, Riyoko Ito, Masaki Matsumoto, Keiichi I.Nakayama, Mutsuo Sekiguchi
- Organizer
  第33回日本分子生物学会・第83回日本生化学学会合同大会
- Data Source
  KAKENHI-PROJECT-20570168

1. TSUZUKI Teruhisa (40155429)

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2. SEKIGUCHI Mutsuo (00037342)

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20. ROBERTSON Ge

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HAYAKAWA Hiroshi 早川 浩

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活性酸素により生じた変異誘発物質の排除機構Principal Investigator

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RNA damages and RNA quality controlPrincipal Investigator

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AD患者の脳神経細胞に蓄積する酸化RNAに結合する蛋白のcDNAクローニングPrincipal Investigator

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Quality Control of mRNAPrincipal Investigator

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哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator

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Elimination of Oxidized Guanine Ribonucleotides in Mammalian CellsPrincipal Investigator

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哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator

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哺乳動物生体内における突然変異原物質の生成とその除去に関わる酵素の解析Principal Investigator

HAYAKAWA Hiroshi 早川浩