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KAWAHARA Yasuhiro  川原 康洋

ORCIDConnect your ORCID iD *help
… Alternative Names

川原 康弘

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Researcher Number 80169755
External Links
Affiliation (based on the past Project Information) *help 1995 – 1997: Kobe University School of Medicine The 1st Department of Internal Medicine Assos, 医学部, 講師
1994: 神戸大学, 医学部・付属病院, 講師
1994: 神戸大学, 医学部附属病院, 講師
1993 – 1994: Kobe University, Faculty of Medicine, Assistant Professor, 医学部・附属病院, 講師
1991 – 1992: Kobe University School of Medicine Hospital Assistant Professor, 医学部附属病院, 講師 … More
1991: 神戸大学, 医学部・附属病院, 講師
1991: 神戸大学, 医学部附属病院, 助手
1986 – 1990: Kobe University, Faculty of Medicine, Research Associate, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Circulatory organs internal medicine
Except Principal Investigator
Circulatory organs internal medicine / 物質生物化学 / Pathological medical chemistry / 代謝生物化学
Keywords
Principal Investigator
血管平滑筋細胞 / 一酸化窒素 / MAPキナーゼ / 血管平滑筋 / GTP結合蛋白質 / 血管作動物質 / アポトーシス / 形質変換 / 増殖 / アンジオテンシンII … More / 腫瘍壊死因子α / インターロイキン1 / アルギニントランスポーター / パキシリン / 接着斑 / 低分子量G蛋白 / シグナル伝達 / アンジオテンシンll / アルギニン / サイトカイン / 一酸化窒素合成酵素 / rho / ras / MAPキナ-ゼ / エンドセリン / アンギオテンシンII / プロテインキナ-ゼ / チロシンリン酸化反応 / ras癌遺伝子 / 発癌遺伝子 / 細胞増殖因子 / Cキナ-ゼ / イノシト-ルリン脂質 … More
Except Principal Investigator
Cキナーゼ / GTP結合蛋白質 / 細胞増殖因子 / 動脈硬化 / Rho / リゾホスファチジルコリン / 内皮由来血管弛緩因子 / 血管内皮細胞 / セロトニン / NO合成酵素 / Ras / Rabphilin-3A / Rab3A / 低分子量GTP結合蛋白質 / ホスホリパーゼC / ras p21 / Serotonin / イノシトールリン脂質代謝 / PDGF / サイクリックAMP / 細胞膜受容体 / CD44 / The ERM family / B-Raf / Protein kinase C / Atherosclerosis / Lysophosphatidylcholine / プロテインキナーゼC / 低比重リポ蛋白質 / small GTP-binding protein / プロテインキナーゼ / Smg GDS / REKS / lysophosphatidylcholine / endothelium-derived relaxing factor / 血管平滑筋 / 酸化低比重リポ蛋白 / 内皮細胞 / GDP / プレニル化 / ras遺伝子 / fos遺伝子 / 分子生物学 / 血管平滑筋細胞 / Atrial natriuretic peptide / Endothelium-derived relaxing factor / Low density lipoprotein / Vascular endothelium / Vascular smooth muscle cell / Histamine / 冠動脈スパスム / ノルエピネフリン / サイクリックGMP / コレステロ-ル / リゾホスホリパ-ゼ / 心房性利尿ペプチド / ヒスタミン / Cardiac hypertrophy / Phosphatidyl inositides / Spontaneous beating / Pertussis toxin / Cultured myocyte / Purinergic receptor / 5HT_2受容体 / P_2受容体 / adenosine trisphosphate(ATP) / プロテインキナ-ゼC / 自動拍動 / 百日咳毒素 / 培養心筋細胞 / プリン受容体 / 心肥大 / ATP / フェニレフリン / プロティンキナ-ゼC / イノシト-ルリン脂質代謝 / 心筋細胞 / Protein Kinase C / GTP-binding Protein / Phospholipase C / Cell Surface Receptor / Phosphoinositide / イノシトール三リン酸 / ジグリセリド / 受容体 / イノシトールリン脂質 / sugar chain / cholesterol metabolism apolipoprotein / カルシウム / 動脈硬化症 / アスパラギン結合糖鎖 / アポ蛋白 / コレステロール代謝 / 冠萎縮 / Protein Kinases / Calcium Ion / Cyclic AMP / Intracellular Messengers / Nuclear Genes / Cell Surface Receptors / カルシウムイオン / 細胞内伝達系 / 核遺伝子 / genetic engineering / transgenic mice / endthelial cell / nitric oxyde synthase / 遺伝子工学 / トランスジェニックマウス / polymorphism / acute myocardial infarction / intracellular calcium / molecular biology / vascular smooth muscle / atherosclerosis / coronary spasm / serotonin / 遺伝子多型性 / 冠動脈攣縮 / 急性心筋梗塞 / 細胞内カルシウム濃度 / 冠動脈萎縮 / ERM-CD44系 / 14-3-3蛋白質 / SMAP / SmgGDS / Rap1 / 低分子量G蛋白質 / Vascular endothelial cells / Oxidized low density lipoprotein / Nitric oxide synthase / 細胞内Ca^2濃度 / リゾホスファチジツコリン / 高比重リボ蛋白質 / 低比重リボ蛋白質 / 一酸化窒素合成酵素 / intracellular calcium concentration / protein kinase C / nitric synthase / high density lipoprotein / low density lipoprotein / vascular endothelial cells / 細胞内Ca^<2+>濃度 / 高比重リポ蛋白質 / rabphilin-3A / Rab / Rho GDI / ゲラニルゲラニル基転移酵素 / ファルネシル基転移酵素 / C末端側ペプチド / smg GDS / rac p21 / rho GDI / rho p21 / 翻訳後修飾 / シナプス小胞 / 標的蛋白質 / 活性制御蛋白質 / signal transduction system / HDL / oxidized LDL / cytosolic calcium / phosphatidyl inositol tunover / endothelial cell / 酸化低比重リポ蛋白質 / 高比重リポ蛋白 / 情報伝達機構 / 細胞内カルシウム / イノシト-ル燐脂質代謝回転 / Tumor markers / GTPase activating protein / GTP exchange protein / prenylation / small GTP-binding proteins / GDI / smgp21 / smgp25 / <ras>___ー p21 / 腫瘍マ-カ- / GTPase活性化蛋白質 / GTP交換反応調節蛋白質 / rasp21 / 癌遺伝子 / cyclic AMP / Ca^<2+> / 心血管疾患 / 培養内皮細胞 / エンドセリン変換酵素 / エンドセリン / 細胞増殖 / リポ蛋白(a) / Cキナ-ゼ / イノシト-ル3リン酸(IP_3) / 細胞内情報伝達機構 / マクロファ-ジ / ホスファチジルイノシト-ル(PI)回転 / コレステロ-ル代謝 / GAP / Aキナーゼ / cーrafー1蛋白質 / cーfos Less
  • Research Projects

    (28 results)
  • Co-Researchers

    (25 People)
  •  血管平滑筋細胞の形質変換、増殖とアポトーシスのシグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  ヒト細胞膜アルギニントランスポーターのクローン化とNO合成における役割Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  The role of endothelial nitric oxide synthase in cardiovascular regulation. -approach using genetic engineering.

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  エンドセリン変換酵素の調節機構ならびに病態モデルでのその発現の変化

    • Principal Investigator
      川嶋 成乃亮
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  血管収縮物質のシグナル伝達と血管平滑筋細胞の遊走、増殖の制御機構Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  Serotonin receptors and ischemic heart disease

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  血管平滑筋細胞における誘導型NO合成酵素の発現制御機構とその病態Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  動脈硬化発症進展におけるリポ蛋白(a)の役割

    • Principal Investigator
      石川 雄一
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  An approach to understand the pathophysiological role of endothelial constitutive nitric oxide synthase

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University School of Medicine
  •  cDNAs and antibodies for small GTP-binding proteins

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  血管平滑筋細胞における血管作動物質のシグナル伝達と低分子量GTP結合蛋白質Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  An approach to understand the interaction of lipoproteins and vascular endothelial cells

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  血管作動物質と細胞増殖因子による血管平滑筋細胞の肥大,増殖機構とその病態Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  cDNAs and antibodies for small GTP-binding proteins

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      代謝生物化学
    • Research Institution
      Kobe University
  •  血管平滑筋におけるrasP21類似低分子量GTP結合蛋白質の役割とその病態Principal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  An approach to understand the mechanism and pathogenesis of production and release of endothelium-derived relaxing factor by molecular and cellular biology technique.

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  細胞増殖シグナル伝達の機構と癌遺伝子産物の作用

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  ヒト単球由来マクロファ-ジの脂質とりこみにおける分子生物学的機構の解析

    • Principal Investigator
      ISHIKAWA Yuichi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  血管平滑筋細胞の増殖機構における血管作動物質と細胞増殖因子の相乗作用とCキナ-ゼPrincipal Investigator

    • Principal Investigator
      川原 康洋
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  cDNAs and Antibodies for Small GTP-binding Proteins

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kobe University
  •  細胞の癌化におけるCキナーゼと癌遺伝子の相互作用

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  細胞増殖因子による細胞周期の制御機構におけるCキナーゼの役割

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kobe University
  •  Regulatory mechanisms of receptor-coupled signal transduction and its pathophysiologic state

    • Principal Investigator
      FUKUZAKI Hisashi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University School of Medicine
  •  An approach to understand the pathogenesis of coronary artery spasm by molecular and cellular biology techniques

    • Principal Investigator
      YOKOYAMA Mitsuhiro
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University School of Medicine
  •  細胞の癌化におけるCキナーゼと癌遺伝子の相互作用

    • Principal Investigator
      高井 義美
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kobe University
  •  Phosphoinositide metabolism in transmembrane signalling

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kobe University
  •  The mechanisms of the initiation and development of atherosclerosis

    • Principal Investigator
      FUKUZAKI Hisashi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kobe University
  •  Mechanisms of signaling from cell surface receptors to nuclear genes.

    • Principal Investigator
      TAKAI Yoshimi
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Kobe University
  • 1.  ISHIKAWA Yuichi (90159707)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 2.  KAIBUCHI Kozo (00169377)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  YOKOYAMA Mitsuhiro (40135794)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 4.  KIKUCHI Akira (10204827)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  TAKAI Yoshimi (60093514)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 6.  KAWASHIMA Yasuhiro (10177678)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 7.  TANIGUCHI Takahiro (20263379)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  AKITA Hozuka (60175792)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  KAWATA Masahito (20224785)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  SASAKI Takuya (40241278)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  YAMASHITA Takayuki (10166671)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SANO Kimihiko (40205993)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SUEMATU Masakuni (90240853)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  FUKUZAKI Hisashi (90030824)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  溝口 明 (90181916)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  山田 充彦
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  INOUE Nobutaka (10304099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  KAWATA Sumio (90183285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  TANAKA Kazuma (60188290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KANO Yoshio (70116200)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  WATANABE Yoshio (00031401)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  白河 卓 (30171044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  高野 新二 (30116222)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  FUJIOKA Yoshio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  矢谷 暁人
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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