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WATAYA Yusuke  綿矢 有佑

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… Alternative Names

綿矢 祐佑  ワタヤ ユウスケ

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Researcher Number 90127598
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013: 岡山大学, 医歯(薬)学総合研究科, 教授
2012: 岡山大学, 医歯(薬)学総合研究科, 名誉教授
2012: 岡山大学, 大学院・医歯薬学総合研究科, 名誉教授
2011: 岡山大学, 医歯(薬)学総合研究科, 教授
2010 – 2011: 岡山大学, 大学院・医歯薬学総合研究科, 教授 … More
2007 – 2008: Okayama University, 大学院・医歯薬学総合研究科, 教授
2007: Okayama University, 大学院・医歯薬総合研究科, 教授
2005 – 2006: 岡山大学, 大学院医歯薬学総合研究科, 教授
2005: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Professor, 大学院・医歯薬学総合研究科, 教授
1999 – 2004: 岡山大学, 大学院・自然科学研究科, 教授
2002: 岡山大学, 大学院自然科学研究科, 教授
2000 – 2002: 岡山大学, 薬学部, 教授
1997 – 2000: 岡山大学, 大学院・薬学研究科, 教授
1999: 岡山大学, 大学院・自然科学研究所, 教授
1999: 岡山大学, 大学院・自然科学系研究科, 教授
1994 – 1998: Okayama University Faculty of Pharmacetical Sciences, Professor, 薬学部, 教授
1996: 岡山大学, 大学院薬学研究科, 教授
1986 – 1994: 岡山大学, 薬学部, 助教授
1990 – 1992: 岡山大学, 藥学部, 助教授
1986: 岡山大, 薬学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological Sciences / Chemical pharmacy / 寄生虫学(含医用動物学) / 寄生虫学(含医用動物学) / Medical pharmacy / Parasitology (including Sanitary zoology) / Environmental pharmacy / Drug development chemistry
Except Principal Investigator
Biological pharmacy … More / Chemical pharmacy / 寄生虫学(含医用動物学) / Drug development chemistry / 寄生虫学(含医用動物学) Less
Keywords
Principal Investigator
マラリア / 細胞死 / エンドヌクレアーゼ / DNA二本鎖切断 / Malaria / 熱帯熱マラリア / PCR / アポトーシス / 化学療法剤 / 制がん剤 … More / 標的分子 / 新規抗マラリア薬 / 薬剤耐性マラリア / dNTPプール / 分子機構 / 不均衡 / ヌクレオシド / アルテミシニン耐性 / 環状下酸化物 / pfmdr 1 / 遺伝子 / 熱帯熱マラリア原虫 / Plasmodium falciparum / malaria / 熱帯熱 / 原虫 / Microtiter plate-hybridization / Cell Death / Apoptosis / endonuclease / DNA Double Strand Breaks / Imbalance / 四日熱マラリア / 卵形マラリア / 三日熱マラリア / DNA診断 / リーシュマニア / マラリア原虫 / 抗寄生虫薬 / 環状過酸化物 / がん / 5-フルオロデオキシウリジン / dNTPプ-ル / デオキシヌクレオシドミリン酸 / Double Strand Breaks / DNA Strand Breaks / Nucleotide Metabolism / dNTP Imbalance / 代謝拮抗剤 / 5-フルオロウラシル / 細胞死の機構 / dNTP Imbalamce Deathi / プールの不均衡 / FM3A細胞DNA二本鎖切断 / デオキシヌクレオシドミリン酸プールの不均衡 / dNTP不均衡死 / パルスフィールドゲル電気泳動 / DNA二本鐙切断 / FM3A細胞 / デオキシヌクレオシド三リン酸プールの不均衡 / ヌクレオチド代謝 / Leishmania tropica, / 3'-Deoxyinosine / Carbocyclic inosin 3'-deoxy-3'-fluoroinosine / Nucleoside analogues / Anti-Leishmania / Anti-parasitic agents / 3'-デオキシイノシン / イノシンアナログ / 熱帯病 / 核酸代謝拮抗剤 / カーボサイクリックイノシン / 3´-デオキシイノシン / ヌクレオシドアナログ / 抗寄生原虫剤 / 病原寄生原虫 / mechanism analysis / johzan alkaloid / antimalarials / drug-resistant / endoperoxides / heat shock protein / ゲルダナマイシン / 環状過酸化化合物 / Heat Shock Protein / 薬剤耐性 / テトラキオキサシクロアルカン類 / 分子基盤 / 寄生虫感染症 / ゲノム創薬 / Mefloquine-resistant / pfmdr1 / New antimalarials / Endoperoxides / Drug-resistant / 遺伝子発現 / pfmdr 1遺伝子 / 薬剤耐性機構 / 薬剤耐性熱帯熱マラリア / RNAi / メフロキン耐性 / 遺伝子変異 / Loop-mediated Isothermal Amplification / LAMP method / Diagnosis of DNA / 多型 / 18S rRNA / 等温遺伝子増幅法 / LAMP法 / antitumor agent / necrosis / protease / intracellular acidification / DNA strand break / cell death / apoptosis / 制ガン剤 / 5-fluoro-2′-deoxyuridine / DUA鎖切断 / ネクローシス / プロテアーゼ / 細胞内酸性化 / DNA鎖切断 / target molecule / protozoa / tropical fever / antisense / Screening / Anti-malaria drug / インターネット / スクリーニンヅ / マラリア治療薬 / ATPase / ミトコンドリア / P.falciparum / アンチセンス / スクリーニング / 抗マラリア薬 / imported malaria / Plasmodium ovale / 18S rRNA gene / DNA diagnosis / malaria parasite / 卵型 / 三日熱 / リボソーム / 診断 / DNA / 18S rRNA遺伝子 / 輸入マラリア / 卵形マラリア原虫 / 18SrRNA遺伝子 / DNA診断法 / 5-Fluorodeoxyuridine / dNTP Pool / DNA Fragmention / Endonuclease / DNA二本切断 / DNA損傷 / Chemotherapy / Cancer / Cell death / dNTP / ス-パ-コイル / M13ファ-ジ / ヌクレア-ゼ / アポトーミス / エンドヌイレアーゼ / ガン / ゲル電気泳動 / αNTPプール / Gadalcanal / Solomon Islands / falciparum / Vivax / Plasmodium / DNA Diagnosis / ガダルカナル島 / ソロモン諸島国 / 核酸誘導体 / 難治性疾患 / 創薬 / 感染症 / 天然生薬資源 / Leishmania donovani / Leishmania major / Hsp90 / Geldanamycin / 抗リーシュマニア活性評価 / アンチモン製剤 / リーシュマニア原虫 / N-89 / シストソミューラ / 広範囲抗寄生虫薬 / マンソン住血吸虫 / プロテオミクス / ゲノミクス / 分子生物学 / 住血吸虫 / 新規治療剤 / 臨床診断法 / 診断マーカー / RNase L / 慢性疲労症候群 / 熱体熱マラリア / IFN / cytidine kinase 2 / uridine / SNP / 抗腫瘍薬 / RNA合成阻害 / 固形がん / エチルニルシチジン / カポトーシス / エンドヌクレア-ゼ / ヌクレオシド代謝 … More
Except Principal Investigator
マラリア / Trp-P-2 / Malaria / DNA鎖切断 / 活性酸素 / 突然変異 / 熱帯熱マラリア / アポトーシス / 代謝拮抗剤 / ヌクレオシド / 染色体異常 / ELISA / 薬剤耐性 / 環状過酸化化合物 / 新規抗マラリア薬 / isoquinoline alkaloids / MS / NMR-LC / LC / 新型変異株 / malaria / PCR / ショウジョウバエ / 細胞内DNA / ワクチン / Plasmodium / HITECマウス / クロロフィリン / サイクリックADPリボース / ネオカルチノスタチン / レチノイド / 生体高分子 / 修復酵素 / 遺伝子損傷 / 温度感受性変異株 / クロロフィル / DNA組換え / genotoxicity / 細胞周期 / チミジル酸ストレス / Drug resistance / Pyrimethamine / 抗マラリア剤 / OFAGE / 電気泳動 / 培養 / 倍養 / ピリメサミン / V79 cell / M13mp2,FM3A cell / replication error / transition mutation / N^4-Aminocytidine / 金属イオン / ONAシークエンス / 複製エラー / 変異原性 / 【N^4】ーアミノデオキシシチジン / 【N^4】ーアミノシチジン / 複製 / トランジション変異 / 塩基置換 / M13ファージ / N^4-アミノdCTP / N^4-アミノシチジン / 試験管内突然変異 / mechanism analysis / johzan alkaloid / antimalarials / drug-resistant / endoperoxides / 薬剤耐性メカニズム / 天然生薬抗マラリア資源 / 作用機序解析 / 耐性機構 / protease inhibitor / hemoglobin degradation / New antimalarials / Endoperoxides / Drug-resistant / アシクロアルカン系 / シクロアルカン系 / 薬剤耐性熱帯熱マラリア / 環状過酸化物 / 薬剤耐性マラリア / structural analysis / biotransformation / metabolites / plant tissue cultures / structure-activity relationship / biological activity / structure-activity relationships / antimicrobial activity / antiHIV activity / antitumor activity / antimalarial activity / 代謝物の構造解析 / 植物組織培養細胞 / 構造-活性相関 / 発がんプロモーション抑制活性 / 抗酸化活性 / イソキノリン アルカロイド / 構造解析 / 生物学的変換 / 代謝物 / 植物組織培養 / 構造活性相関 / 生物活性 / イソキノリンアルカロイド / Antimalarial activity / Febrifugine / Alkaloid / Dichroa febrifuga / テルペノイド / 甘松香 / 抗マラリア作用 / フェブリフジン / アルカロイド / 常山 / vector / animal model / immunoresponse / drug developmen / vaccine / Parasitic adaptation / Tropical infectious diseases / ベクター / 実験動物モデル / 免疫応答 / 新薬開発 / 寄生適応 / 熱帯感染症 / 宿主・寄生体相互作用 / 新興・再興感染症 / 化学療法剤 / China / Myanmar / Indonesia / Thailand / New variant / Acridine orange staining / Molecular diagnosis / リボゾームRNA遺伝子 / 四日熱マラリア / 分子疫学 / ミャンマー / 中国 / インドネシア / タイ / アクリジンオレンジ染色 / 遺伝子診断 / Enterovirus / Rotavirus / Viral diarrhea / New variant form / PCR diagnosis / Rapid diagnosis / Vietnam / 下痢症ウイルス / 卵形マラリア / 新型マラリア原虫 / 小児感染症 / エンテロウイルス / ロタウイルス / ウイルス性下痢症 / 遺伝子診断法 / 迅速診断法 / ベトナム / mosquito fish / ultrasonic diagnosis / DNA diagnosis / Anopheles acridine orange / Solomon Islands / 酵素欠損 / G6PD / 血清診断 / ソロモン / G6PD欠損 / 超音波診断 / DNA診断 / 血液検査 / ハマダラカ / ソロモン諸島 / light / 8-methoxypsoralen / N-nitrosamines / DNA damage / fluorometry / 螢光分析法 / フォスゲン / 遺伝子損傷阻害物質 / 光 / DNAー本鎖切断 / 蛍光光度分析 / 近紫外光 / 8ーメトキシソラレン / ニトロソアミン / 蛍光分析 / DNAクロスリンク / catalase-enriched FM3A細胞 / λファージ / FM3A細胞 / プロファージ誘発 / Trp-P-2(NHOH)、クロロフィル / 遺伝子発現制御 / DNA高次構造 / カンプトテシン / DNAトポイソメラーゼ / O^6-メチルグアニンと突然変異 / ヌクレオチドプール不均衡とDNA切断 / 姉妹染色分体交換 / DNA切断 / ヘテロサイクリックアミン / ヒト排泄物中変異原 / 青綿 / MeIQx / N-OH-Glu-P-1 / N-OH-Trp-P-2 / 免疫 / 生態系 / マラリア伝播 / 抗マラリア薬 / 遺伝子 / エンジイン / 血管新生 / ドラッグデザイン / RNA合成阻害剤 / p53 / カスパーゼ / 抗がん剤 / 植物成分 / 食品 / キトサン / 太陽光 / rpsL遺伝子 / タキソ-ル / ハリコンドリンB / 変異スペクトラム / DNAアダクト / 大腸菌 / rpsL / タキリ-ル / ハリコンンドリンB / 核酸代謝 / 逆転写酵素 / ヌクレアーゼ / 光酸化反応 / オリゴヌクレオチド / 寄生原虫 / DNAポリメラ-ゼ / HIV / AIDS / シアノ基 / ヌクレオチド / マクロファ-ジ / リポソ-ム / ヌクレオシドアナログ / リ-シュマニア / SDDS / 駆虫薬 / マクロファージ / イノシンアナログ / リポリーム / ヌクレオシド・アナログ / リーシュマニア / 原虫 / リン酸化 / ヒストンH1キナ-ゼ / トポイソメラ-ゼ / ユビキチン活性化酵素 / クロロフィリン誘導体 / キイロショウジョウバエ / λファ-ジ / Trp-P-2(NHOH) / 染色体凝縮 / 蛋白質の脱リン酸化 / 蛋白質のリン酸化 / H1ヒストン / 温度感受性変異 Less
  • Research Projects

    (50 results)
  • Research Products

    (131 results)
  • Co-Researchers

    (98 People)
  •  経皮吸収型抗マラリア薬開発のための基礎研究Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Okayama University
  •  Study of novel anti-leishmanial drugPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Okayama University
  •  Study of new broad spectrum of anti-parasitic agent and basis of molecular base of itPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Environmental pharmacy
    • Research Institution
      Okayama University
  •  広範囲抗寄生虫薬の開発のための標的治療の分子基盤の確立Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  慢性疲労症候群診断法の開発と発症因子の探索Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      Okayama University
  •  New antiamlarial drug development research against drug-resistant Plasmodium falciparum

    • Principal Investigator
      KIM Hyesook
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      OKAYAMA UNIVERSITY
  •  New antiamlarial drug development research including mechanism analysis of drug-resistant Plasmodium falciparumPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      OKAYAMA UNIVERSITY
  •  RNA合成阻害を作用機序とする新規抗腫瘍薬3'-エチニルシチジンの分子標的の探索Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  新しい抗マラリア薬の開発と抗マラリア薬耐性機構の解析に関する研究Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  Development of new antimalarial endoperoxides and it's antimalarial mechanism

    • Principal Investigator
      KIM Hye-sook
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  New Antimalarial Drug Research for Multidrug-resistant MalariaPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Okayama University
  •  Development of Novel Antimalarial Drugs Based on Plant Alkaloids

    • Principal Investigator
      OSHIMA Yoshiteru
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Tohoku University
  •  Study on Biological Activity of Isoquinoline-Type Alkaloids

    • Principal Investigator
      IWASA Kuniko
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Chemical pharmacy
    • Research Institution
      Kobe Pharmaceutical University
  •  ドラッグデザインによる新しい抗がん剤の合成

    • Principal Investigator
      松田 彰
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Hokkaido University
  •  マラリア制圧の総合戦略

    • Principal Investigator
      TANABE Kazuyuki
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Osaka Institute of Technology
  •  Development of simple and specific DNA diagnostic method of Malaria in Malaria endemic areasPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  トランスジェニックマウスを用いた,発がん物質による遺伝子損傷とその抑制の解析

    • Principal Investigator
      根岸 和雄
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  トランスジェニックマウスを用いた、発がん物質による遺伝子損傷とその抑制の解析

    • Principal Investigator
      根岸 和雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  生体高分子機能を修飾する抗がん化合物の合成と作用解析

    • Principal Investigator
      松田 彰
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  Molecular approach for malaria control

    • Principal Investigator
      KITA Kiyoshi, 小島 荘明 (小島 莊明)
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Development of Anti-malarial Drug and it's Molecular TargetPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Okayama University
  •  Study of the molecular mechanisms of cell death induced by the dNTP pool imbalance.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  生体高分子機能を修飾する抗がん化合物の合成と作用解析

    • Principal Investigator
      松田 彰
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  細胞死を引き起こすDNA二本鎖切断酵素遺伝子を標的とする化学療法剤の開発Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  Surveys on new human malaria in South East Asia

    • Principal Investigator
      KAWAMOTO Fumihiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University School of medicine
  •  Development of a new DNA diagnostic system for the species-specific detection of human malaria parasites using specific nucleotide sequences of the 18S ribosomal RNA gene.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  細胞死を引き起こすDNA二本鎖切断酵素遺伝子を標的とする化学療法剤の開発Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  Surveys on malaria and enteroviruses in Vietnamese children

    • Principal Investigator
      ISOMURA Shin
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  機能の創生を目指すヌクレオシドの化学合成

    • Principal Investigator
      松田 彰
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  遺伝子損傷と突然変異の分子基盤

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  dNTP Imbalance and DNA Double Strand Breaks in Mouse FM3A Cells and the Mechanism of Cell DeathPrincipal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  遺伝子損傷と突然変異の分子基盤

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  機能の創生を目指すヌクレオシドの化学合成

    • Principal Investigator
      松田 彰
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  Studies on epidemiology and control of malaria in the Solomon Islands

    • Principal Investigator
      SASA Manabu
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Toyama Univ. of International Studies
  •  DNA Diagnosis of Malaria Using PCR Techniques.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Okayama University
  •  dNTP Pool Imbalance Induced Endonuclease : Mechanism of All Death.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  がん細胞における染色体の不安定化と再配列に関与する分子遺伝学的研究

    • Principal Investigator
      瀬野 捍二
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  リポリームなどDDSの工夫を加えたヌクレオシド系抗寄生原虫剤の開発研究

    • Principal Investigator
      ISHII Akira
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      国立予防衛生研究所
  •  デオキシヌクレオシドミリン酸プ-ルの不均衡が誘導するDNA二本鎖切断酵素の解析Principal Investigator

    • Principal Investigator
      綿矢 有佑
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  Studies on DNA damages in vivo and in vitro by highly sensitive fluorometric analysis

    • Principal Investigator
      HAYATSU Hikoya
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okayama University
  •  がん細胞における染色体の不安定化と再配列に関与する因子の分子遺伝学的研究

    • Principal Investigator
      瀬野 悍二
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  がん細胞における染色体の不安定化と再配列に関与する因子の分子遺伝学的研究

    • Principal Investigator
      瀬野 悍二
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  発がん性ヘテロサイクリックアミンによる遺伝子損傷とその修飾

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Okayama University
  •  抗アラリア剤ピリメサミンの標的酵素遺伝子のクローニングとその薬剤耐性機構の解明

    • Principal Investigator
      ISHII Akira
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Okayama University Medical School
  •  Deoxyribonucleoside Triphosphate Imbalance: The Mechanism of Cell Death and DNA-Double Strand Breaks.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University, Faculty of Pharmaceutical Sciences
  •  食品の加熱で生ずる発癌物質の遺伝子損傷作用とその促進・抑制に関する研究

    • Principal Investigator
      早津 彦哉
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Okayama University
  •  Base changes in the replication of DNA induced by nucleotide analogs and the use for in vitro mutagenesis

    • Principal Investigator
      HAYATSU Hikoya
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Anti-Parasitic Activity of Nucleoside Analogues against Leishmania tropica and Leishmania donovani.Principal Investigator

    • Principal Investigator
      WATAYA Yusuke
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Chemical pharmacy
    • Research Institution
      Okayama University, Faculty of Pharmaceutical Sciences

All 2013 2012 2011 2010 2009 2008 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 最新医学「感染症医薬品開発の現状」薬剤耐性マラリアに対する新規治療薬開発の現状2012

    • Author(s)
      金 惠淑、佐藤 聡、森田将之、綿矢有佑
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Book] 薬剤耐性マラリアに対する新規治療薬開発の現況。最新医学、67 (11)2012

    • Author(s)
      金 惠淑、佐藤 聡、森田将之、綿矢有佑
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Book] 最新医学「感染症医薬品開発の現状」薬剤耐性マラリアに対する新規治療薬開発の現状2012

    • Author(s)
      金 惠淑、佐藤 聡、森田将之、綿矢有佑
    • Publisher
      最新医学社
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Book] 核膜の裏打ちタンパク質Lamin-B1。生体の科学, Vol.62 (5)2011

    • Author(s)
      佐藤聡、金 惠淑、綿矢有佑
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Book] 実験医学2005

    • Author(s)
      綿矢 有佑, 金 惠淑
    • Total Pages
      5
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Book] 実験医学2005

    • Author(s)
      綿矢 有佑, 金 惠淑
    • Total Pages
      5
    • Publisher
      抗マラリヤ薬の開発 : 過去-現在-未来
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Book] 実験医学2005

    • Author(s)
      綿矢有佑, 金恵淑
    • Total Pages
      5
    • Publisher
      抗マラリア薬の開発 : 過去-現在-未来
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Book] 実験医学 5.抗マラリア薬の開発:過去-現在-未来2005

    • Author(s)
      綿矢 有佑, 金 惠淑
    • Total Pages
      5
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Book] 抗原虫薬2004

    • Author(s)
      金 恵淑, 綿矢 有佑, 木村幹男, 益山新樹, 野島正朋
    • Total Pages
      5
    • Publisher
      臨床と微生物
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Book] 抗原虫薬2004

    • Author(s)
      金 惠淑, 綿矢 有佑, 木村幹男, 益山新樹, 野島正朋
    • Total Pages
      5
    • Publisher
      臨床と微生物
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Applications of triphenylpyrylium salt-sensitized electron transfer photo-oxygenation reactions to the synthesis of benzo-fused 1,4-diaryl-2,3- dioxabicyclo[2.2.2]octanes as new antimalarial cyclic peroxides.2013

    • Author(s)
      Kamata, M., Hagiwara, J., Hokari,T., Suzuki,C., Fujino,R., Kobayashi,S., Kim,H.-S.and Wataya, Y
    • Journal Title

      Research on Chemical Intermediate

      Volume: 39 Pages: 127-137

    • URL

      http://link.springer.com/article/10.1007/s11164-012-0637-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Andirolides HeP from the flower of andiroba (Carapa guianensis, Meliaceae)2012

    • Author(s)
      Tanaka Y, Sakamoto A, Inoue T, Yamada T, Kikuchi T, Kajimoto T, Muraoka O, Sato A, Wataya Y, Kim H.-S, and Tanaka R.
    • Journal Title

      Tetrahedron

      Volume: 68 Pages: 3669-77

    • URL

      http://www.sciencedirect.com/science/article/pii/S0040402011019727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Andirolides HeP from the flower of andiroba (Carapa guianensis, Meliaceae).2012

    • Author(s)
      Tanaka, Y., Sakamoto, A., Inoue, T., Yamada, T., Kikuchi, T., Kajimoto, T., Muraoka, O., Sato, A., Wataya, Y., Kim, H.-S, and Tanaka, R.
    • Journal Title

      Tetrahedron

      Volume: 68 Pages: 3669-3677

    • URL

      http://www.sciencedirect.com/science/article/pii/S0040402011019727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Andirolides H-P from the flower of andiroba (Carapa guianensis, Meliaceae)2012

    • Author(s)
      Tanaka Y., Sakamoto A., Inoue T., Yamada T., Kikuchi T., Kajimoto T., Muraoka O., Sato A., Wataya Y., Kim H.-S., Tanaka R.
    • Journal Title

      Tetrahedron

      Volume: 68 Issue: 18 Pages: 3669-3677

    • DOI

      10.1016/j.tet.2011.12.076

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-23659212
  • [Journal Article] Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-2512012

    • Author(s)
      Morita M., Sanai H., Hiramoto A., Sato A., Hiraoka O., Sakura T., Kaneko O., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
    • Journal Title

      Journal of Proteome Research

      Volume: 11 Issue: 12 Pages: 5704-5711

    • DOI

      10.1021/pr3005315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-23659212
  • [Journal Article] Plasmodium falciparumendoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251.2012

    • Author(s)
      Morita, M., Sanai, H., Hiramoto, A., Sato, A., Hiraoka, O., Sakura, T., Kaneko, O., Masuyama, A., Nojima, M., Wataya, Y. and Kim, H.-S.
    • Journal Title

      J Proteome Res.

      Volume: 11 Pages: 5704-5711

    • URL

      http://pubs.acs.org/doi/pdf/10.1021/pr3005315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Plasmodium falciparumendoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-2512012

    • Author(s)
      Morita, M., Sanai, H., Hiramoto, A., Sato, A., Hiraoka, O., Sakura, T., Kaneko, O., Masuyama, A., Nojima, M., Wataya, Y. and Kim, H.-S.
    • Journal Title

      J Proteome Res.

      Volume: 11 Pages: 5704-11

    • URL

      http://pubs.acs.org/doi/pdf/10.1021/pr3005315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011

    • Author(s)
      Taniguchi, T., Kumagai, T., Shimogawara, R., Ichinose, S., Hiramoto, A., Sato, A., Morita, M., Nojima, M., Kim, H.-S., Wataya, Y., Ohta, N.
    • Journal Title

      arasitology International

      Volume: 60 Pages: 231-236

    • URL

      http://www.sciencedirect.com/science/article/pii/S1383576911000225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011

    • Author(s)
      Taniguchi T., Kumagai T., Shimogawara R., Ichinose S., Hiramoto A., Sato A., Morita M., Nojima M., Kim H.-S., Wataya Y., Ohta N.
    • Journal Title

      Parasitology International

      Volume: 60 Pages: 231-236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89.2011

    • Author(s)
      Taniguchi T, Kumagai T, Shimogawara R, Ichinose S, Hiramoto A, Sato A, Morita M, Nojima M, Kim HS, Wataya Y, Ohta N.
    • Journal Title

      Parasitol Int.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Antimalarial Activity of 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) and Its Carboxylic Acid Derivatives2011

    • Author(s)
      Sato A., Kawai S., Hiramoto A., Morita M., Tanigawa N., Nakase Y., Komichi Y., Matsumoto M., Hiraoka O., Hiramoto K., Tokuhara H., Masuyama A., Nojima M., Higaki K., Hayatsu H., Wataya Y., Kim H.-S.
    • Journal Title

      Parasitology International

      Volume: 60 Issue: 4 Pages: 488-492

    • DOI

      10.1016/j.parint.2011.08.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22590099
  • [Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7- Tetraoxaspiro[7.11] nonadec-4-yl)hexan-1-ol.2011

    • Author(s)
      Sato A., Hiramoto A., Morita M., Matsumoto M., Komich Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
    • Journal Title

      Parasitology International

      Volume: 60 Pages: 270-3

    • URL

      http://dx.doi.org/10.1016/j.parint.2011.04.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.2011

    • Author(s)
      Sato A., Hiramoto A., Morita M., Matsumoto M., Komichi Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
    • Journal Title

      Parasitology International

      Volume: 60 Pages: 270-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Antimalarial activity of 6-(1,2,6,7-tetraoxaspiro [7.11]nonadec-4-yl)hexan- 1-ol (N-251) and its carboxylic acid derivatives.2011

    • Author(s)
      Sato A, Kawai S, Hiramoto A, Morita M, Tanigawa N, Nakase Y, Komichi Y, Matsumoto M, Hiraoka O, Hiramoto K, Tokuhara H, Masuyama A, Nojima M, Higaki K, Hayatsu H, Wataya Y, Kim HS.
    • Journal Title

      Parasitol. Int.

      Volume: 60(4) Pages: 488-92

    • URL

      http://www.sciencedirect.com/science/article/pii/S138357691100136X

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Schistosomicidal and antifecundity effects of oral treatment of synthetic endo-peroxide N-892011

    • Author(s)
      Taniguchi T., Kumagai T., Shimogawara R., Ichinose S., Hiramoto A., Sato A., Morita M., Nojima M., Kim H.-S., Wataya Y., Ohta N.
    • Journal Title

      Parasitology International

      Volume: 60 Pages: 231-6

    • URL

      http://dx.doi.org/10.1016/j.parint.2011.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7- Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol.2011

    • Author(s)
      Sato, A., Hiramoto, A., Morita, M., Matsumoto, M., Komich, Y., Nakase, Y., Tanigawa, N., Hiraoka, O., Hiramoto, K., Hayatsu, H., Higaki, K., Kawai, S., Masuyama, A., Nojima, M., Wataya,Y., Kim, H.-S.
    • Journal Title

      Parasitol. Int.

      Volume: 60 Pages: 270-273

    • URL

      http://www.sciencedirect.com/science/article/pii/S1383576911000444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Antimalarial activity of endoperoxide compound 6-(1,2,6,7-tetraoxaspiro [7.11]nonadec-4-yl)hexan-1-ol.2011

    • Author(s)
      Sato, A., Hiramoto, A., Morita, M., Matsumoto M., Komichi Y., Nakase, Y., Tanigawa N., Hiraoka, O., Hiramoto, K., Hayatsu, H., Higaki, K., Kawai, A., Masuyama, A., Nojima, M., Wataya, Y., Kim, H.-S.
    • Journal Title

      Parasitol Int.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] tetraoxaspiro [7.11]nonadec-4-yl)hexan- 1-ol (N-251) and its carboxylic acid derivatives2011

    • Author(s)
      Sato, A, Kawai, S., Hiramoto, A., Morita, M., Tanigawa, N., Nakase, Y., Komichi, Y., Matsumoto, M., Hiraoka, O., Hiramoto, K., Tokuhara, H., Masuyama, A., Nojima, M., Higaki, K., Hayatsu, H., Wataya,Y., Kim, H.-S.
    • Journal Title

      Parasitol. Int

      Volume: 60 (4) Pages: 488-492

    • URL

      http://www.sciencedirect.com/science/article/pii/S138357691100136X

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol2011

    • Author(s)
      Sato A., Hiramoto A., Morita M., Matsumoto M., Komichi Y., Nakase Y., Tanigawa N., Hiraoka O., Hiramoto K., Hayatsu H., Higaki K., Kawai S., Masuyama A., Nojima M., Wataya Y., Kim H.-S.
    • Journal Title

      Parasitology International

      Volume: 60 Issue: 3 Pages: 270-273

    • DOI

      10.1016/j.parint.2011.04.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22590099
  • [Journal Article] Schistosomicidal and anti-fecundity effects of oral treatment of synthetic endoperoxide compound N-892011

    • Author(s)
      Taniguchi T, Kumagai T, Shimogawara R, Ichinose S, Hiramoto A, Sato A, Morita M, Nojima M, Kim HS, Wataya Y, Ohta N
    • Journal Title

      Parasitology International

      Volume: 60 Issue: 3 Pages: 231-236

    • DOI

      10.1016/j.parint.2011.02.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21406008, KAKENHI-PROJECT-22390024, KAKENHI-PROJECT-22790393
  • [Journal Article] Geranyl derivatices of isoquinoline alkaloids show increased biological activities.2010

    • Author(s)
      Nishiyama, Y., Iwasa, K., Okada, S., Takeuchi, S., Moriyasu, M., Kamigauchi, M., Koyama, J., Takeuchi, A., Tokuda, H., Kim, H.-S., Wataya, Y., Takeda, K., Liu, Y., Wu, P., Bastow, K., Akiyama, T. and Lee, K
    • Journal Title

      Heterocycles

      Volume: 81 Pages: 1193-1229

    • URL

      http://www.heterocycles.jp/newlibrary/downloads/PDF/21203/81/5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Selective accumulation of rhodacyanine in plasmodial mitochondria is related to the growth inhibition of malaria parasites2010

    • Author(s)
      Morisaki, D., Kim, H.-S., Inoue, H., Terauchi, H., Kuge, S., Naganuma, A., Wataya, Y., Tokuyama, H., Ihara, M. and Takasu, K
    • Journal Title

      Chemical Science

      Volume: 1 Pages: 206-209

    • URL

      http://pubs.rsc.org/en/content/articlepdf/2010/sc/c0sc00125b

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Protein expression profiles of necrosis and apoptosis induced by 5-Fluoro-2´-deoxyuridine in mouse cancer cells.2010

    • Author(s)
      Sato, A., Hiramoto, A., Wataya, Y. and Kim, H.-S.
    • Journal Title

      Journal of Proteome Research

      Volume: 9 Pages: 1329-2338

    • URL

      http://pubs.acs.org/doi/abs/10.1021/pr9010537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Journal Article] Toxoplasma gondii : A simple high throughput assay for drug screening in vitro2009

    • Author(s)
      Jin C., Kaewintajuk K., Jiang J., Jeong W., Kamata M., Kim H.-S., Wataya Y. and Park H.
    • Journal Title

      Exp. Parasitol. 121

      Pages: 132-136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041049
  • [Journal Article] 抗マラリア薬2008

    • Author(s)
      綿矢 有佑
    • Journal Title

      ファルマシア 44

      Pages: 32-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041049
  • [Journal Article] Detection of malaria parasites in mosquitoes from a malaria endemic area Chakaria, Bangladesh2008

    • Author(s)
      Tangin A., komichi Y., Wagatsuma Y., Rashidul H., Wataya Y. and Kim H.-S.
    • Journal Title

      Biol. Pharm. Bull. 31

      Pages: 703-708

    • NAID

      110006680510

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041049
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Hexamethylenebis(4-carbamoyl-1- alkvlpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshlda, M., Namba, T, Kim, T.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki,K
    • Journal Title

      Bioorg. Med. Chem. Lett. 16

      Pages: 2758-2760

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis (4-carbamoy1-1- alkylpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
    • Journal Title

      Bioorg. Med. Chem. Lett. 16

      Pages: 2758-2760

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Nexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
    • Journal Title

      Bioorg. Med. Chem. Lett. (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] An apoptotic pathway of 3'-Ethynylcytidine(ECyd) involving the inhibition of RNA synthesis mediated by RNase L.2006

    • Author(s)
      Naito T, Yokogawa T, Kim HS, Matsuda A, Sasaki T, Fukushima M, Kitade Y, Wataya Y
    • Journal Title

      Nucleic Acids Symp Ser. 50

      Pages: 103-104

    • Data Source
      KAKENHI-PROJECT-18659029
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N, N'-Hexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
    • Journal Title

      Bioorg.Med.Chem.Lett., (In press)

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis (4-carbamoyl-1-alkylpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y., Kourai, H., Kakuta, H., Sasaki, K.
    • Journal Title

      Bioorg.Med.Chem.Lett. 16

      Pages: 2758-2760

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Antimalarial Effect of Bis-pyridinium Salts, N,N'-Hexamethylenebis(4-carbamoyl-1-alkylpyridinium bromide).2006

    • Author(s)
      Fujimoto, K., Morisaki, D., Yoshida, M., Namba, T., Kim, H.-S., Wataya, Y, Kourai, H., Kakuta, H., Sasaki, K.
    • Journal Title

      Bioorg.Med.Chem.Lett., (In press)

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Proteome and transcriptome analysis of 5-fluoro-2'-deoxyuridine-induced cell death mechanisms.2006

    • Author(s)
      Sato A, Miyazaki E, SatakeA, Hiramoto A, Hiraoka O, Miyake T, Kim HS, Wataya Y
    • Journal Title

      Nucleic Acids Symp Ser. 50

      Pages: 101-102

    • Data Source
      KAKENHI-PROJECT-18659029
  • [Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
    • Journal Title

      Chem.Pharm.Bull., 53(6)

      Pages: 653-661

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim., H.-S., Wataya, Y., Kitade, Y.
    • Journal Title

      Biol.Biophy.Res.Comm., 20,330(4)

      Pages: 1168-1175

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b- D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis..2005

    • Author(s)
      Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.I
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(3)

      Pages: 227-232

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Mini-Reviews Med. chem. 5

      Pages: 1035-1043

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
    • Journal Title

      Org.Biomol.Chem. 3

      Pages: 1245-1251

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H-S., Fukushima, M.,, Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(4)

      Pages: 233-242

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl) uracil ( EUrd ) on RNA Synthesis.2005

    • Author(s)
      Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H-S., Wataya,Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(3)

      Pages: 227-232

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim.H.-S., Wataya, Y., Kitada, Y., Matsuda, A., Shuto, S.
    • Journal Title

      Org.Bjomol. Chem., 3

      Pages: 1245-1251

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Sequence analysis of the 5'flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24.4

      Pages: 233-242

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005

    • Author(s)
      Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Tetrahedron 61

      Pages: 9961-9968

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b- D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis..2005

    • Author(s)
      Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.I
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(3)

      Pages: 227-232

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Kumura, N., Izumi, M.Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
    • Journal Title

      Biosci.Biotech.Biochem. 69(11)

      Pages: 2250-2253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and in vitro antimalarial activity of some simple peroxyplakoric acid analogues.2005

    • Author(s)
      Liu, H., Jin, H., Zhang, Q., Wu, Y., Kim, H.-S., Wataya, Y.
    • Journal Title

      Chinese J.Chem. 23

      Pages: 1469-1473

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y, Kitade, Y.
    • Journal Title

      Biol.Biophy.Res.Comm., 20,330(4)

      Pages: 1168-1175

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
    • Journal Title

      Biosci.Biotech.Biochem., 69(11)

      Pages: 2250-2253

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and evaluation of □-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
    • Journal Title

      Chem. Pharm. Bull. 53.6

      Pages: 653-661

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y, Kitade, Y., Matsuda, A., Shuto.S.
    • Journal Title

      Org. Biomol. Chem. 3

      Pages: 1245-1251

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and evaluation of □-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
    • Journal Title

      Chem. Pharm. Bull. 53 (6)

      Pages: 653-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, T.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24(4)

      Pages: 233-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto.S.
    • Journal Title

      Org. Biomol. Chem. 3

      Pages: 1245-1251

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005

    • Author(s)
      Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Tetrahedron 61

      Pages: 9961-9968

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
    • Journal Title

      Biosci. Biotech. Biochem. 69(11)

      Pages: 2250-2253

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Mini-Reviews Med. Chem. 5

      Pages: 1035-1043

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Mini-Reviews Med.Chem. 5

      Pages: 1035-1043

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y, Matsuda, A., Shuto.S.
    • Journal Title

      Org.Biomol.Chem., 3

      Pages: 1245-1251

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Fumura, N., lzumi, M., Nakajima, S., Shimizu, S., Kim, H, -S., Wataya, Y., Baba,N.
    • Journal Title

      Biosci. Biotech. Biochem. 69(11)

      Pages: 2250-2253

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim.H.-S., Wataya, Y., Brun, R, Ihara,M
    • Journal Title

      Chem. Pharm. Bull., 53(6)

      Pages: 653-661

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Sequence analysis of the 5--flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya,Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24 (4)

      Pages: 233-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y., Baba, N.
    • Journal Title

      Biosci.Biotech.Biochem., 69(11)

      Pages: 2250-2253

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y., Kitade, Y.
    • Journal Title

      Biol. Biophy. Res. Comm. 20, 330(4)

      Pages: 1168-1175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim, H.-S., Wataya, Y, Kitade, Y.
    • Journal Title

      Biol. Biophy. Res. Comm. 20, 330.4

      Pages: 1168-1175

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-^-D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis.2005

    • Author(s)
      Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24 (3)

      Pages: 227-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.2005

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
    • Journal Title

      Org.Biomol.Chem., 3

      Pages: 1245-1251

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Inhibitory Mechanisms of 1-(3-Cethynyl-□-D-ribo-pentofuranosyl)uracil(EUrd)on RNAsynthesis.2005

    • Author(s)
      Yokogawa, T, Kanda, H., Takatori, S, Takenaka, K, Naito, T., Sasaki, T, Matsuda, A., Fukushima, M., Kim, H.-S, Wataya, Y.I
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24.3

      Pages: 227-232

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(4)

      Pages: 233-242

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
    • Journal Title

      Chem.Pharm.Bull., 53(6)

      Pages: 653-661

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 1, 2, 4, 5 - Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H-S., Wataya,Y.
    • Journal Title

      Mlnl-Reviews Med. chem. 5

      Pages: 1035-1043

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Inhibitory Mechanisms of 1-(3-C-ethynyl-b-D-ribo-pentofuranosyl)uracil (EUrd) on RNA Synthesis.2005

    • Author(s)
      Yokogawa, T., Kanda, H., Takatori, S., Takenaka, K., Naito, T., Sasaki, T., Matsuda, A., Fukushima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids 24(3)

      Pages: 227-232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.2005

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids, 24(4)

      Pages: 233-242

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3 ' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim.H.-S., Wataya, Y., Kitada,Y.
    • Journal Title

      Biol.Biophy.Res.Comm. 20,330(4)

      Pages: 1168-1175

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3' overhang regions and their ability to suppress human RNase L protein expression.2005

    • Author(s)
      Ueno, Y., Naito, T., Kawada, K., Sibata, A., Kim, H.-S., Wataya, Y., Kitabe, Y.
    • Journal Title

      Biol.Biophy.Res.Comm. 20,330(4)

      Pages: 1168-1175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Mini-Reviews Med.chem. 5

      Pages: 1035-1043

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.2005

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Mini-Reviews Med.chem. 5

      Pages: 1035-1043

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and in vitro antimalarial activity of some simple peroxyplakoric acid analogues.2005

    • Author(s)
      Liu, H., Jin, H.Zhang, Q., Wu, Y., Kim, H, -S, Wataya,Y.
    • Journal Title

      Chinese J.Chem. 23

      Pages: 1469-1473

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005

    • Author(s)
      Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      Tetrahedron, 61

      Pages: 9961-9968

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution.2005

    • Author(s)
      Wu, J.-M., Kunikawa, S., Tokuyasu, T., Masuyama, A., Nojima, M., Kim, H.-S., Wataya, Y
    • Journal Title

      Tetrahedron, 61

      Pages: 9961-9968

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Synthesis and biological activity of fatty acid conjugate of quinine.2005

    • Author(s)
      Kumura, N., Izumi, M., Nakajima, S., Shimizu, S., Kim, H.-S., Wataya, Y, Baba, N.
    • Journal Title

      Biosci. Biotech. Biochem. 69.11

      Pages: 2250-2253

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis and evaluation of b-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis.2005

    • Author(s)
      Takasu, K, Shimogama, T, Saiin, C, Kim, H.-S, Wataya, Y, Brun, R, Ihara, M.
    • Journal Title

      Chem.Pharm.Bull. 53(6)

      Pages: 653-661

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL,2004

    • Author(s)
      Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
    • Journal Title

      Parasitolgy Res. 93

      Pages: 499-530

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] p Delocalized b-carbolinium cations as potential antiamlarials.2004

    • Author(s)
      Takasu, K., Shimogama, T., Saiin, C., Kim, H.-S., Wataya, Y., Ihara, M.
    • Journal Title

      Bioorg.Med.Chem.Lett. 14

      Pages: 1689-1692

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004

    • Author(s)
      Kim, Y.-C, Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T, -H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park,H.
    • Journal Title

      Biol.Pharm.Bull. 25

      Pages: 748-750

    • NAID

      110003608846

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Duffy antigen is important for lethality of the lethal strain P. yoelii 17XL2004

    • Author(s)
      Akimitsu, N., Kim, H-S., Ono, K., Wataya, Y., Torii, M.Sekimizu,K.
    • Journal Title

      Parasltolgy Res. 93

      Pages: 499-503

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 抗原虫薬2004

    • Author(s)
      金 惠淑, 綿矢 有佑, 木村幹男, 益山新樹, 野島正朋
    • Journal Title

      臨床と微生物

      Pages: 5-5

    • NAID

      10015599985

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL2004

    • Author(s)
      Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
    • Journal Title

      Parasitolgy Res. 93

      Pages: 499-530

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004

    • Author(s)
      Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park, H.
    • Journal Title

      Biol.Pharm.Bull. 25

      Pages: 748-750

    • NAID

      110003608846

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Duffy antigen is important for lethality of the lethal strain P.yoelii 17XL2004

    • Author(s)
      Akimitsu, N., Kim, H.-S., Ono, K., Wataya, Y., Torii, M., Sekimizu, K.
    • Journal Title

      Parasitolgy Res. 93

      Pages: 499-530

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004

    • Author(s)
      Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Rark, H.
    • Journal Title

      Biol.Pharm.Bull. 27(5)

      Pages: 748-750

    • NAID

      110003608846

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] Antimalarial Activity of Lavandulyl Flavanones Isolated from the Roots of Sophora flavescens.2004

    • Author(s)
      Kim, Y.-C., Kim, H.-S., Wataya, Y., Sohn, D.-H., Kang, T.-H., Kim, M.-S., Kim, Y.-M., Lee, K.-M., Chang, J.-D., Park, H.
    • Journal Title

      Biol.Pharm.Bull. 25

      Pages: 748-750

    • NAID

      110003608846

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
    • Journal Title

      SBO (In press)

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Synthesis of 5'-methylenearisteromycin and its 2-fluoro congener with potent antimalarial activity due to the parasite S-adenosyl homocysteine hydrolase Inhibition.

    • Author(s)
      Takagi, T., Sukeda, M., Kim, H.-S., Wataya, Y., Kitade, Y., Matsuda, A., Shuto, S.
    • Journal Title

      SBO (In press)

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      MRMC (In press)

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids (In press)

    • Data Source
      KAKENHI-PROJECT-14021072
  • [Journal Article] Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene : Identification of a new polymorphism related with effects of 5-fluorouracil.

    • Author(s)
      Hasegawa, T., Kim, H.-S., Fukushima, M., Wataya, Y.
    • Journal Title

      Nucleosides Nucleotides Nucleic Acids (In press)

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Journal Article] 1,2,4,5-Tetraoxan cycloalkanes : Synthesis and Antimalarial Activity.

    • Author(s)
      Masuyama, A., Wu, J-M., Nojima, M., Kim, H.-S., Wataya, Y.
    • Journal Title

      MRMC (In press)

    • Data Source
      KAKENHI-PROJECT-16390031
  • [Patent] 特許新規抗住血吸虫剤2008

    • Inventor(s)
      綿矢有佑, 金恵淑, 平本晃子, 佐藤聡, 太田伸生, 熊谷貴, 下河原理江子, 谷口斎恵
    • Industrial Property Rights Holder
      岡山大学
    • Filing Date
      2008-07-01
    • Data Source
      KAKENHI-PROJECT-19041049
  • [Patent] ヘムへの配位能を有する抗マラリア活性化合物2006

    • Inventor(s)
      樋口 恒彦, 大宮 弘久, 梅澤 直樹, 金 惠淑, 綿矢 有佑
    • Industrial Property Rights Holder
      樋口 恒彦
    • Industrial Property Number
      2006-049678
    • Filing Date
      2006-02-28
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Patent] ヘムへの配置能を有する抗マラリア活性化合物2006

    • Inventor(s)
      樋口恒彦, 大宮弘久, 梅澤直樹, 金惠子淑, 綿矢 有佑
    • Industrial Property Rights Holder
      樋口恒彦
    • Industrial Property Number
      2006-049678
    • Filing Date
      2006-02-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Patent] ヘムへの配位能を有する抗マラリア活性化合物2006

    • Inventor(s)
      樋口恒彦, 大宮弘久, 梅澤直樹, 金恵淑, 綿矢有佑
    • Industrial Property Rights Holder
      樋口恒彦
    • Industrial Property Number
      2006-049678
    • Filing Date
      2006-02-28
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14021072
  • [Patent] ヘムへの配位能を有する抗マラリア活性化合物2006

    • Inventor(s)
      樋口 恒彦, 大宮 弘久, 梅澤 直樹, 金 惠淑, 綿矢 有佑
    • Industrial Property Rights Holder
      樋口 恒彦
    • Industrial Property Number
      2006-049678
    • Filing Date
      2006-02-28
    • Data Source
      KAKENHI-PROJECT-16390031
  • [Presentation] 経皮吸収型抗マラリア薬の開発研究2013

    • Author(s)
      中村由香、片本 茜、佐藤 聡、檜垣和孝、綿矢有佑、金 惠淑
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 経皮吸収型抗マラリア薬の開発研究2013

    • Author(s)
      中村由香、片本 茜、佐藤 聡、檜垣和孝、綿矢有佑、金 惠淑
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] 難治性感染症治療薬の開発研究2013

    • Author(s)
      金 惠淑、佐藤 聡、森田将之、綿矢有佑、熊谷貴、下河原理江子、太田伸生
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] 難治性感染症治療薬の開発研究2013

    • Author(s)
      金 惠淑、佐藤 聡、森田将之、綿矢有佑、熊谷 貴、下河原理江子、太田伸生
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜、神奈川
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] Drug development research for antimalarial endoperoxide N-2512012

    • Author(s)
      Masayuki Morita, Akiko Hiramoto, Kazuaki Okada, Tatsuya Wakimoto, Akane Katamoto, Hiroki Watanabe, Takuma Takahashi, Chikako Imada, Akira Sato, Kazutaka Higaki, Yusuke Wataya, Hye-Sook Kim
    • Organizer
      Forum Cheju 15; The 15th Japan-Korea Parasitologists’ Seminar
    • Place of Presentation
      Miyazaki, Japan
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 新規抗マラリア薬・環状過酸化化合物の開発研究2012

    • Author(s)
      森田 将之、平本 晃子、佐藤 聡、岡田 和朗、鎌井 一気、脇本 達也、林 孝輔、片本 茜、渡部 裕紀、高橋 拓真、今田 智加子、平岡 修、野島 正朋、檜垣 和孝、綿矢 有佑,金 惠淑
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] 新規抗マラリア薬・環状過酸化化合物の開発研究2012

    • Author(s)
      森田 将之、平本 晃子、佐藤 聡、岡田 和朗、鎌井 一気、脇本 達也、林 孝輔、片本 茜、渡部 裕紀、高橋 拓真、今田 智加子、平岡 修、野島 正朋、檜垣 和孝、綿矢有佑,金 惠淑
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 環状過酸化化合物N-251の生物学的利用能向上を目的とする開発研究2012

    • Author(s)
      片本 茜、脇本達也、渡部裕紀、森田将之、林 孝輔、佐藤 聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金 惠淑
    • Organizer
      第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
    • Place of Presentation
      前橋、群馬
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] Drug development research for antimalarial endoperoxide N-2512012

    • Author(s)
      Masayuki Morita, Akiko Hiramoto, Kazuaki Okada, Tatsuya Wakimoto, Akane Katamoto, Hiroki Watanabe, Takuma Takahashi, Chikako Imada, Akira Sato, Kazutaka Higaki, Yusuke Wataya, Hye-Sook Kim
    • Organizer
      Forum Cheju 15; The 15th Japan-Korea Parasitologists’ Seminar
    • Place of Presentation
      Miyazaki, Japan
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] 環状過酸化化合物N-251 の生物学的利用能向上を目的とする開発研究2012

    • Author(s)
      片本 茜、脇本達也、渡部裕紀、森田将之、林 孝輔、佐藤 聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金 惠淑
    • Organizer
      第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
    • Place of Presentation
      前橋、群馬
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 環状過酸化化合物N-251の生物学的利用能向上を目的とする開発研究2012

    • Author(s)
      片本 茜、脇本達也、渡部裕紀、森田将之、林 孝輔、佐藤 聡、綿矢有佑、高橋拓真、今田智加子、檜垣和孝、金 惠淑
    • Organizer
      第72回日本寄生虫学会東日本支部会, 第10回分子寄生虫・マラリアフォーラム
    • Place of Presentation
      前橋、群馬
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫体内のヘモゾイン蓄積量に与える影響2011

    • Author(s)
      谷口斎恵、熊谷 貴、下河原理江子、平本晃子、佐藤 聡、金 惠淑、綿矢有佑、太田伸生
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-23659212
  • [Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫体内のヘモゾイン蓄積量に与える影響2011

    • Author(s)
      谷口斎恵、熊谷貴、下河原理江子、平本晃子、佐藤聡、金惠淑、綿矢有佑、太田伸生
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 新規抗住血吸虫薬の開発研究2010

    • Author(s)
      金惠淑、平本晃子、佐藤聡、森田将之、熊谷貴、下河原理江子、谷口斎恵、奈良武司、太田伸生、綿矢有佑
    • Organizer
      第33回 日本分子生物学会年会 第83回 日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 合成環状過酸化化合物N-89投与によるマンソン住血吸虫のヘモグロビン代謝への影響2010

    • Author(s)
      谷口斎恵、熊谷貴、下河原理江子、平本晃子、佐藤聡、金惠淑、綿矢有佑、太田伸生
    • Organizer
      第79回 日本寄生虫学会大会
    • Place of Presentation
      旭川
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 新規抗住血吸虫薬の開発研究2010

    • Author(s)
      金 惠淑、平本晃子、佐藤 聡、森田将之、熊谷 貴、下河原理江子、谷口斎恵、奈良 武司、太田伸生、綿矢有佑
    • Organizer
      第33回日本分子生物学会年会、第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] 環状過酸化化合物N-89投与時のマンソン住血吸虫プロテオーム解析2010

    • Author(s)
      平本晃子、佐藤聡、森田将之、綿矢有佑、熊谷貴、下河原理江子、谷口斎恵、太田伸生、金惠淑
    • Organizer
      第79回 日本寄生虫学会大会
    • Place of Presentation
      旭川
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-22390024
  • [Presentation] Proteome, analysis of schistosoma mansoni in the treatment of the infected animals with a new antischistosomal endoperoxide, N-892008

    • Author(s)
      綿矢有佑
    • Organizer
      8 th Awaji International Forum on Infection and Immunity
    • Place of Presentation
      淡路
    • Year and Date
      2008-09-09
    • Data Source
      KAKENHI-PROJECT-19041049
  • 1.  HAYATSU Hikoya (10012593)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  NEGISHI Kazuo (70116490)
    # of Collaborated Projects: 16 results
    # of Collaborated Products: 0 results
  • 3.  KIM Hye-sook (70314664)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 123 results
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  • 35.  CHANSUDA Won
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  • 36.  WONGSRICHANALAI Chansuda
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  • 92.  TRAN Tim Hie
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  • 93.  三宅 恭司
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  • 94.  WONGSRICHANA チャンスタ
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  • 96.  福川 清史
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    # of Collaborated Products: 0 results
  • 97.  FUKUKAWA Kiyoshi
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    # of Collaborated Products: 0 results
  • 98.  KUMAGAI Takashi
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    # of Collaborated Products: 1 results

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