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SUZUKI Norio  鈴木 紀夫

ORCIDConnect your ORCID iD *help
Researcher Number 10010050
Affiliation (based on the past Project Information) *help 2005: 国際医療福祉大学, 保健学部, 非常勤講師
2003 – 2004: International University of Health and Welfare, Radiological Sciences, Professor, 保健学部, 教授
1996 – 2002: Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
1993 – 1996: 東京大学, 医学部, 教授
1989 – 1995: 東京大学, 医学部(医), 教授 … More
1992: 東大, 医・放射線基礎, 教授
1990: University of Tokyo, Faculty of Medicine, Professor, 医学部・医学科, 教授
1989: University of Tokyo, Faculty of Medicine, Professor, 医学部(医), 室長
1987 – 1989: 東京大学, 医学部, 教授
1988: 東京大学, 医学部・放射線基礎医学教室, 教授
1986 – 1987: 東京大学, 医学部(医), 教授
1986: 東大, 医学部, 助教授
1985: 東京大学, 医, 助教授 Less
Review Section/Research Field
Principal Investigator
Radiation science / 環境影響評価(含放射線生物学) / Radiation science / Biological Sciences
Except Principal Investigator
Radiation science / 放射線5生物学 / 環境影響評価(含放射線生物学)
Keywords
Principal Investigator
先行指標 / 放射線感受性 / 分割照射 / p53 / MOLT-4 / JNK / 細胞死 / SAPK / p41 / DNA-PK … More / 転移の予防と治療 / シグナル伝達 / 放射線誘導タンパク / 低酸素性細胞 / Cell death / X線 / 放射線 / MOLT-4細胞 / c-myc / 放射線抵抗性の誘導 / がん転移 / マウス移植腫瘍 / ^<31>P-MRS / wortmannin / Heat sensitization / セラミド / Radiation fibrosis / cell death / Hyperthermia / X-rays / p41抗体 / X線誘導蛋白p41 / CTCR(腫瘍細胞游出率) / マウス腫瘍 / Mouse Tumors / PO_2 / Flow Cytometry / Micronuclei / ニュートロン / がんの転移 / U937細胞 / XRCC4 / Wortmannin / 温熱 / 放射線誘発アポトーシス / p41タンパク / 放射線誘発細胞死 / リン酸化・脱リン酸化 / 細胞死(アポトーシス) / アポトーシス / Micronucleus Assay / リンパ球浸潤 / Micronucleus assay / 色素排除試験 / Reoxygenation(再酸素化) / 血流 / dose fractionation / murine tumors / neutrons / CTCR assay / Prevention and control of metastasis / CTCR(腫瘍細胞遊出率) / OK432 / 線量配分 / U937 cells / apoptosis / hyperthermia / 温熱療法 / リン酸化特異抗体 / Akt / 温熱高感受性 / 細胞死、アポトーシス / p53 null / Apoptosis / U937 Cells / p41 specific antibody / Ceramide / Ionizing radiation-induced apoptosis / 放射線細胞死 / p41特異抗体 / macrophage / Radiation pneumonitis / マクロファージ / 照射後の肺障害 / MUC1 mucin / anti-p41 antibody / X ray induced protein p41 / Indicator of sensitivity / MUC1 / 感受性指標 / Radiosensitization / Ku proteins / Anti-DNA-PK antibody / DNA-dependent protein kinase (DNA-PK) / Radiosensitivity / 二重鎖切断 / 温熱増感 / DNA-PKサブユニット / DNA-PK抗体 / Ku抗原 / ハイパーサーミア / 放射線増感効果 / ハイバーサーミア / Kuタンパク質 / 抗DNA-PK抗体 / DNA依存性プロテインキナーゼ(DNA-PK) / Predictive assay / Anti-p41 antibody / Radiation-induced proteins / SET / 抗ペプチド抗体 / 放射線誘導蛋白 / MOLT4白血病細胞 / Set遺伝子 / 抗p41抗体 / 放射線誘導タンパク質 / Local tumor irradiation / Lymphnode metastasis / Lung metastasis / Clonogenic tumor cell release / Mouse tumors / prevention and control of metastasis / 局所放射線照射の影響 / リンパ節転移 / 肺転移 / Predictive Assay / Blood Flow / Reoxygenation / Tumor Radioresponse / p0_2 / ^<31>PーMRS / 腫瘍照射効果 / NMR(MRS、MRI) / 正常組織 / 腫瘍 / NMR(MRS,MRI) / 腫瘍・正常組織 / ニュートロン照射 / X線照射 / 腫瘍細胞の游出(率) / 腫瘍細胞の遊出率 / 遠心分流 / エルトリエイター / 腫瘍細胞の遊出 / 細胞応答シグナル / 放射線療法 / 応答特異抗体 / DNA array / 感受性 / c-Myc / DNA・PK / 感受性修飾 / NBS1 / 先行指導 / 温熱による放射線の増感 / 奇形 / p53欠失マウス / ナイミ-ヘン症候群 / Ataxia telangiectasia遺伝子 / DNA依存性プロテインキナーゼ / 重イオン / プロトン / 細胞組織応答 / 感受性増強 / 放射線応答指標 / 放射線治療 / 癌関連遺伝子単クローン抗体 / 単クローン抗体 Ki67・PCNA / Low dose Survival Curve / Ki,BUdR Indeces / Micronucleus test / pO_2 … More
Except Principal Investigator
温熱感受性 / 放射線感受性 / 放射線 / 温熱療法 / 細胞死 / DNA-PK / 遺伝子導入 / HSP72 / DNA修復 / X線 / Radiation / MUC1 / LDR / HDR / 熱耐性 / 血管新生 / 放射線照射 / 生理因子 / 色素排除試験 / プロテインキナーゼ / 培養細胞 / p53 / 放射線治療 / P53 / X-irradiation / Neutron / Predictive assay / Fractionated irradiation / Radiation therapy / Energy metabolism / Tumor Metabolism / P-31 MRS / エネルギー代謝 / NMR分光法 / ニュートロン / NMR分光方 / エネルギ-代謝 / MMR分光法 / 先行指標 / 腫瘍組織 / ニュ-トロン / 分割照射 / Ataxia telangiectasia / Gene transfer / Cell death / Radiosensitivity / DNA Repair / DNA damage / 融合細胞 / X線感受性 / AT細胞 / アタキシア細胞 / サザン解析 / DNA損傷 / Cancer / DNA repair / Ionizing radiation / 癌 / Tumor anitigen / ムチン / 放射線応答 / 腫瘍抗原 / MUCl / Tumor antigen / DNA ladder / Dye exclusion test / Gene cloning / Gene transfection / Cell fusion / Heat resistance / Heat sensitivity / DNAラダー / 遺伝子クローニング / 細胞融合 / 温熱抵抗性 / BRACHYTHERAPY / LOW DOSE RATE CONTINUOUS RADIATION / HIGH DOSE RATE FRACTIONATED RADIATION / 低線量率分割照射 / 密封小線源治療 / 低線量率連続照射 / 高線量率分割照射 / PHYSIOLOGICAL FACTORS / NMR / ANGIOGENESIS / BLOOD FLOW / METABOLISM / TUMOR BED / RADIATION THERAPY / CANCER / MRS / aerobic glycolysis / metabolic status / cancer / 核磁気共鳴 / 血流 / 代謝 / 腫瘍床 / 腫瘍 / MRスペクトロスコピー / Heat ShocR Protein / 熱感受性 / ハイパーサーミヤ / グルコース / 膜作用物質 / Heat Shock Protein / DNA断片化 / DNA切断再結合 / DNA切断 / WAF1 / アポトーシス / シグナルトランスダクション / TNF / NMRスペクトロスコピー / VEGF / 放射線抵抗性腫瘍 / 再発腫瘍 / 血管内皮細胞増殖因子 / 腫瘍血管新生 / Ku抗原 / 温熱増感 / H7 / 阻害剤 / 温熱耐性 / 分子標的治療 / 遺伝子治療 / 免疫療法 / がん診断 / がん治療 / がんの放射線療法 / がん化学療法 / がんの分子標的治療 / がんの遺伝子治療 / がん免疫 / がんの質的診断法 / がんの早期診断法 / ヒートショックタンパク質 / 癌抑制遺伝子 / 癌遺伝子 / 癌細胞 Less
  • Research Projects

    (45 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (54 People)
  •  細胞応答シグナルを利用する新放射線療法の開発Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      International University of Health and Welfare
  •  応答特異抗体とDNA arrayによる放射線感受性予測システムの構築Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Radiation science
    • Research Institution
      International University of Health and Welfare
      The University of Tokyo
  •  Clarification of response mechanism in U937 cells against heat treatmentPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      International University of Health and Welfare
      The University of Tokyo
  •  放射線細胞応答メカニズムと感受性予測Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      International University of Health and Welfare
      The University of Tokyo
  •  Inhibition of DNA-PK activity by phosphorothioate oligonucleotides

    • Principal Investigator
      HOSOI Yoshio
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  Analysis of signal transduction and nuclear denaturation in radiation-induced cell deathPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  放射線感受性予測の基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  遺伝子発現を利用した照射効果測定

    • Principal Investigator
      HIRANO Kazuya
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCE
      The University of Tokyo
  •  Study to control radiation lung damages.Principal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  New Assay Methods for Monitoring Radiation Effects.Principal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  放射線感受性予測の基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  癌関連遺伝子を標的とする遺伝子操作による温熱感受性の制御

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nara Medical University
  •  放射線感受性決定機構におけるDNA-PKの関与

    • Principal Investigator
      酒井 一夫
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  DNA-dependent protein kinase and cellular response to ionizing radiationPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      University of Tokyo
  •  腫瘍の放射線分割照射に関する基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  癌関連遺伝子を標的とする遺伝操作による温熱感受性の制御

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nara Medical University
  •  放射線感受性決定におけるプロテインキナーゼの関与

    • Principal Investigator
      酒井 一夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  「放射線治療向上のための生物学的基礎・臨床研究の将来検討」Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  放射線抵抗性癌における腫瘍血管新生の形成及びその制御に関する研究

    • Principal Investigator
      伊藤 正光
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      The University of Tokyo
  •  Preparation of monoclonal antibodies for monitoring radiation effectsPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Radiation science
    • Research Institution
      University of Tokyo
  •  Cloning of a gene responsible for the cellular sensitivity to environmental stresses

    • Principal Investigator
      SAKAI Kazuo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      環境影響評価(含放射線生物学)
    • Research Institution
      University of Tokyo
  •  腫瘍の放射線分割照射に関する基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  がん診断治療の基礎研究

    • Principal Investigator
      濱岡 利之
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  癌関連遺伝子からみた温熱療法抵抗性癌の細胞特性

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nara Medical University
  •  細胞の温熱感受性の機構とその修飾因子の解析

    • Principal Investigator
      SAKAI Kazuo
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  High dose rate fractionated interstitial radiation as an alternative to low dose rate continuous interstitial radiation

    • Principal Investigator
      INOUE Toshihiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Radiation science
    • Research Institution
      OSAKA UNIVERSITY
  •  腫瘍の放射線分割照射に関する基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  癌関連遺伝子からみた温熱療法抵抗性癌の細胞特性

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nara Medical University
  •  ASSESSMENT OF THE PHYSIOLOGICAL FACTORS ON THE REGROWING TUMOR AFTER RADIATION THERAPY

    • Principal Investigator
      ITOH Masamitsu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      UNIVERSITY OF TOKYO
  •  がん治療における放射線の時間的線量配分に関する研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  癌関連遺伝子からみた温熱抵抗性癌の細胞持性

    • Principal Investigator
      大西 武雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nara Medical University
  •  がん治療における放射線の時間的線量配分に関する基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Experimental radiological study for prevention and control of metastasisPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      University of Tokyo
  •  がん治療における放射線の時間的線量配分に関する基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Basic Studies on Physiological Factors in RadiocurabilityPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      University of Tokyo
  •  温熱耐性の発現機構の解明とその修飾に関する研究

    • Principal Investigator
      田中 敬正
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  Assessment of the Response of murine NR-S1 tumor following irradiation monitored by P-31 NMR Spectroscopy

    • Principal Investigator
      ITOH Masamitsu
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Radiation science
    • Research Institution
      Faculty of Medicine, University of Tokyo
  •  がん治療における放射線の時間的線量配分と制癌剤併用効果に関する研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん治療における放射線の時間的線量配分と制癌剤併用効果に関する研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  温熱耐性の発現機構の解明とその修飾に関する研究

    • Principal Investigator
      田中 敬正
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kansai Medical University
  •  がん治療における放射線の時間的線量配分と制癌剤併用効果に関する研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Experimental radiology for prevention and control of metastasisPrincipal Investigator

    • Principal Investigator
      SUZUKI Norio
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      University of Tokyo
  •  がん転移の予防と治療のための基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  がん転移の予防と治療のための基礎研究Principal Investigator

    • Principal Investigator
      鈴木 紀夫
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Characterization of X-ray-sensitive cells and isolation of the gene responsible for their radiosensitivity.

    • Principal Investigator
      SAKAI Kazuo, 岡田 重文
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      放射線5生物学
    • Research Institution
      Faculty of Medicine, University of Tokyo

All 2004

All Journal Article

  • [Journal Article] Suramin Sensitizes Cells to Ionizing Radiation by Inactivating DNA-Dependent Protein Kinase.2004

    • Author(s)
      Hosoi, Y., Suzuki N.et al.
    • Journal Title

      Radiat.Res. 162

      Pages: 308-314

    • Data Source
      KAKENHI-PROJECT-12217029
  • [Journal Article] Radiosensitization by hyperthermia in chicken B lymphocyte cell line2004

    • Author(s)
      Yin, H.-L., Suzuki, N., et al.
    • Journal Title

      Radiat.Res 162

      Pages: 433-441

    • Data Source
      KAKENHI-PROJECT-16659325
  • [Journal Article] Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53.2004

    • Author(s)
      Komiyama, S., Suzuki N.et al.
    • Journal Title

      Biochem.Biophys.Res.Commun 323

      Pages: 816-822

    • Data Source
      KAKENHI-PROJECT-16659325
  • [Journal Article] Potentiality of DNA-dependent protein kinase to phosphorylate Ser46 of human p53.2004

    • Author(s)
      Komiyama, S., Suzuki N.et al.
    • Journal Title

      Biochem.Biophys.Res.Commun 323

      Pages: 816-822

    • Data Source
      KAKENHI-PROJECT-12217029
  • [Journal Article] Up-regulation of DNA-dependent protein kinase activity and Sp1 in2004

    • Author(s)
      Hosoi, Y., Suzuki N.et al.
    • Journal Title

      Int.J.Oncol. 25

      Pages: 461-468

    • Data Source
      KAKENHI-PROJECT-16659325
  • [Journal Article] Radiosensitization by hyperthermia in chicken B lymphocyte cell line2004

    • Author(s)
      Yin, H.-L., Suzuki, N., et al.
    • Journal Title

      Radiat.Res 162

      Pages: 433-441

    • Data Source
      KAKENHI-PROJECT-12217029
  • [Journal Article] Suramin Sensitizes Cells to Ionizing Radiation by Inactivating DNA-Dependent Protein Kinase.2004

    • Author(s)
      Hosoi, Y., Suzuki N.et al.
    • Journal Title

      Radiat.Res. 162

      Pages: 308-314

    • Data Source
      KAKENHI-PROJECT-16659325
  • [Journal Article] Up-regulation of DNA-dependent protein kinase activity and Sp1 in2004

    • Author(s)
      Hosoi, Y., Suzuki N.et al.
    • Journal Title

      Int.J.Oncol. 25

      Pages: 461-468

    • Data Source
      KAKENHI-PROJECT-12217029
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