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Iwakura Yoichiro  岩倉 洋一郎

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… Alternative Names

IWAKURA Yoichiro  岩倉 洋一郎

岩倉 洋一朗  イワクラ ヨウイチロウ

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Researcher Number 10089120
Other IDs
External Links
Affiliation (Current) 2025: 東京大学, 大学院農学生命科学研究科(農学部), 名誉教授
Affiliation (based on the past Project Information) *help 2023: 東京大学, 大学院農学生命科学研究科(農学部), 名誉教授
2015 – 2022: 東京理科大学, 研究推進機構生命医科学研究所, 教授
2011 – 2016: 東京理科大学, 付置研究所, 教授
2012 – 2014: 東京理科大学, 生命医科学研究所, 教授
2012: 東京理科大学 生命医科学研究所, 生命医科学研究所, 教授 … More
1992 – 2011: 東京大学, 医科学研究所, 教授
2007: The Institute of Medical Science, Professor
2000: 東京大学, 医学科研究所, 教授
2000: University of Tokyo, Institute of Medical Science, Professor, 医科学研究所・ヒト疾患モデル動物センター, 教授
1998: 東京大学, 医科学研究科, 教授
1994: 東京大学, 医科研, 教授
1988 – 1992: 東京大学, 医科学研究所, 助教授
1989: 東京大学, 医学研究所・ウイルス部, 助教授
1989: 東京大学, 医科学研究所ウイルス感染研究部, 助教授
1988: 東京大学, 医科学研究所・ウイルス感染部, 助教授
1987: 東京大学, 医科学研究所, 教授
1987: 東京大学, 医科学研究所・ウィルス感染部, 助教授
1986: 東京大学, 医学部研究所・ウィルス感染部, 助教授 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Laboratory animal science / Laboratory animal science / Virology / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Basic Section 42040:Laboratory animal science-related / Complex systems / Basic Section 49070:Immunology-related / Immunology / Immunology … More
Except Principal Investigator
… More Biological Sciences / Basic Section 42040:Laboratory animal science-related / Neuroscience in general / Ophthalmology / Laboratory animal science / Applied veterinary science / Laboratory animal science / Basic veterinary science/Basic zootechnical science / Immunology / Parasitology (including Sanitary zoology) / Functional biochemistry / Virology / 寄生虫学(含医用動物学) / Immunology / Hematology / Applied animal science / 畜産学(含草地学) / Laboratory animal science / Bacteriology (including mycology) / Bacteriology (including Mycology) Less
Keywords
Principal Investigator
サイトカイン / 関節リウマチ / トランスジェニックマウス / ノックアウトマウス / IL-1 / HTLV-I / 自己免疫 / IL-6 / 自己免疫疾患 / インターフェロン … More / C型レクチン / マイクロアレイ / IL-1レセプターアンタゴニスト / 疾患モデル動物 / 遺伝子欠損マウス / 遺伝子改変マウス / 自然免疫 / 免疫学 / マウス / 標的遺伝子組換え / Autoimmune / IL-17 / 炎症性疾患 / 疾患モデルマウス / 樹状細胞 / 関節炎 / 発癌 / コラーゲン誘導関節炎 / インターロイキン-1 / HTLV-1 / 炎症 / 腫瘍 / TNF-α / 疾患モデル / HTLV-I-Tgマウス / Disease model / Tax / Cytokine / Inflammation / Transgenic mouse / Arthritis / C型レクチン受容体 / CTRP / Th17 / 獲得免疫 / 連鎖解析 / ゲノム / モデルマウス / IL-1Rアンタゴニスト / 発生工学 / 遺伝子 / 免疫応答 / HIV / エイズ / IFN-γ / エンドトキシンショック / IL-1 receptor antagonist / IL-1 signal / negative selection / 実験動物学関連 / 多発性硬化症 / 腎炎 / PAQR 受容体 / CTRP ファミリー分子 / 免疫 / PAQR / 腫瘍形成制御機構 / 線維化 / アレルギー / DSS誘発性大腸炎 / アレルギー性気道炎症(AAI) / Gene knockout mice / 感染防御 / 腸管免疫 / シングルセル / 免疫疾患 / 腸内細菌叢 / 大腸がん / Innate immunity / C-type lectin / Dendritic Cells / Inflmmation / Rheumatiod arthritis / cvtokine / Animal disease models / IL-1R antagonist / Animal Models1 / Rheumatoid Arthritis / IL-IRアンタゴニスト / model mice / antoimmune disease / knockout mice / transgenic mice / Rheumatoid arthritis / コンジェニック / 病態モデルマウス / HIV-I-Tgマウス / IL-12 / HTLV-I Tgマウス / HIV-Tgマウス / HTLV-L Tgマウス / IL-1β / IL-1α / 成人T細胞白血病ウイルス(HTLV-I) / 自己抗体 / Cytekine / 精子形成 / メタロチオネイン / 実験動物 / C1qTNF / Th17鈿胞 / 間接リウマチ / Th17細胞 / 自己応答性 / IL-17F / IL-17A / 慢性関節リウマチ / 生体防御 / 細菌感染 / 応用植物 / 発生・分化 / シグナル伝達 / 細胞・組織 / 応用動物 / 病態モデル動物 / ウイルス / OX40 / CD40L / トランジェニックマウス / T細胞 / アレルギー・ぜんそく / 遺伝要因 / 抗体産生 / CXCR4 / loxpシステム / Cre / ケモカイン / 慢性関節炎 / IFN-γレセプター / B16メラノーマ / ConA誘導肝炎 / 炎症性発熱 / インターフェロンγ / インターロイキン1 / 標的遺伝子組み換え / 検索 / システム / コンピューター / ソフト / 維持 / 管理 / ConA肝炎 / ES細胞 / 遺伝子相同組換え / 遺伝子標的法 / 癌抑制遺伝子 / 癌 … More
Except Principal Investigator
トランスジェニックマウス / ノックアウトマウス / サイトカイン / C型レクチン / 自然免疫 / 癌遺伝子 / 遺伝子改変マウス / 体外受精 / 自己免疫疾患 / 受精 / C型レクチン受容体 / 真菌感染 / 樹状細胞 / 標的遺伝子組換え / 胚培養 / 相同遺伝子組換え / ES細胞 / マウス / 形質転換動物 / ヒト疾患モデル / 生物機能モデル / 自然免疫受容体 / NO / MyD88 / interferon gamma / インターフェロン ガンマ / トキソプラズマ / LTR / HIV / B-1細胞 / SDF-1 / TAG-1 / Inflammation / 関節リウマチ / IL-1 / コンタクチン / IL-3 / アポトーシス / STAT5 / 発生工学 / Toxoplasma / トキソプラズマ原虫 / バベシア原虫 / chimeras / parthenogenesis / endothelin / acrosin / fertilization / oocyte maturation / 減数分裂 / 卵丘 / 遺伝子発現 / キメラ胚 / 単為発生 / アクロシン / 卵成熟 / 遺伝子改変動物 / C-type lectin / 炎症反応 / 獲得免疫 / 感染防御 / 感染免疫 / 腫瘍免疫 / 炎症 / 初期胚 / セレクチン / ガラクトース転移酵素 / 疾患モデル / シグナル伝達 / マウスエイズ / ネコ免疫不全ウイルス / サル免疫不全ウイルス / 遺伝子解析 / キメラマウス / 遺伝子トラップ / 多段階発癌 / 再構成卵巣 / 哺乳動物初期胚 / T細胞受容体遺伝子再配列 / 成人性T細胞白血病 / 発癌遺伝子 / animal model / AdipoR / Paqr / CTRP / CRISPR-Cas / Dectin-1 / 腸管免疫 / 腸内細菌叢 / 炎症性腸疾患 / 粘膜免疫 / 遺伝子欠損マウス作製 / 真菌 / 抑制型C型レクチン受容体 / 炎症・がん / DAMP / 免疫原性核酸 / がん / HMGB1 / 恒常性維持 / 免疫シグナル伝達 / Innate immunity / Autoimmune / Dendritic cells / Rheumatoid arthritis / cytokine / Animal disease models / 網羅的解析 / 炎症性疾患 / 疾患モデル動物 / 自己免疫 / B-1 effector cells / acquired immunity / innate immunity / systemic erthetodes / Toll like receptor(TLR) / T.gondii-derived HSP70(TgHSP70) / 抑制性B-2細胞 / IRAK4 / TLR4 / TLR2 / ループス腎炎 / B-2抑制性細胞 / 全身性エリトマトーデス / B-1エフェクター細胞 / 自然免疫と獲得免疫 / TgHSP70 / トキソプラズマ毒性分子 / 全身性エリテマトーデス / NO産生 / Toll-like receptor / トキソプラズマ由来ストレス蛋白TgHSP70 / retinal vasculitis / uveitis / micro array / toxoplasmic retinochoroiditis / トキソプラズマ性網脈絡膜炎 / 網膜血管炎 / ブドウ膜炎 / マイクロアレイ / トキソプラズマ件網脈絡膜炎 / Genetic altered animals / Knockout / Embryonic Srem cell / ノックアウト / TRANSGENIC MICE / OSTEOCLASTOGENESIS INHIBITORY FACTOR / OSTEOCLAST DIFFERENTIATION FACTOR / OSTEOCLASTS / BONE DESTRUCTION / 破骨細胞形成抑制因子 / 破骨細胞分化因子 / 破骨細胞 / 骨破壊 / interferon gamma knock out mouse / organ specificity / heat shock protein / chorioretinitis / インターフェロンガンマノックアウトマウス / 臓器特異性 / 熱ショック蛋白 / 網脈絡膜炎 / Latent Infection / CpG Methylation / Transcription / 細胞内シグナル伝達 / 潜伏HIV再活性化シグナルによるLTRの脱メチル化制御 / ヌクレオソーム / クロマチン免疫沈降法 / Histone Code / 潜伏感染 / 転写抑制 / 潜状感染 / CpGメチル化 / 転写 / VTR / IFN-γ knockout (KO) mice / SAG1 / T.g.HSP30 / T.g.HSP70 / T.gondii stress protein HSP70 / cDNA microarray / Toxoplasma gondi / danger signal / IFN-γ / マイクロアレー / TgHSP30遺伝子 / TgHSP70遺伝子 / testesterone / RAG遺伝子 / HSP70自己抗体 / IFN-γKOマウス / SAG1遺伝子 / T.g.HSP30遺伝子 / T.g.HSP70遺伝子 / トキソプラズマ原虫ストレス蛋白HSP70 / cDNAマイクロアレイ / scid mice / stem cell / transgenic mice / 血液幹細胞 / ケモカイン / expression / Lac Z gene / motor coordination / behavior / NB-3 deficient mice / cell adhesion molecule / contakutin subgroup / 遺伝子変異マウス / NB-3 / 発現 / LacZ遺伝子 / 運動機能障害 / 行動実験 / NB-3欠損マウス / 神経接着分子 / コンタクチンサブグループ / Adenosine / axon guidance / Knockout mouse / Gene targeting / アデノシン / 免疫グロブリンスーパーファミリー / 脳神経細胞 / 細胞接着分子 / Apoptosis / Stress Response / RheumatoidArthritis / Contact Hypersensitivity / Antibody Production / Knockout mice / エンドトキシンショック / ディファレンシャル・ディスプレイ / 細菌誘導性肝炎 / T細胞フライミング / ストレス応答 / 接触過敏症反応 / 抗体産生 / Reverse transcriptase inhibitor / Neutralizing antibody / Vpr transgenic mouse / Membrane fusion inhibitor / CXCR4 inhibitor / Drug resistance / CCR5 inhibitor / Protease inhibitor / u-CRM1 / rev / フィットネス / 転写制御 / tat / CTL / 抗ウイルス剤 / 発症予防ワクチン / ケモカインレセプター阻害剤 / hu-PBL-SCIDマウス / 遺伝子発現制御 / CXCR4拮抗剤 / T140 / HIV-1 / 逆転写酵素阻害剤 / 中和抗体 / Vprトランスジェニックマウス / 膜融合阻害剤 / CXCR4阻害剤 / 薬剤耐性 / CCR5阻害剤 / プロテアーゼ阻害剤 / 神経細胞 / 接着分子 / Proliferation / Differentiation / Apotosis / Transcription factor / Cytokine receptor / Cytokine / サイトカインレセプター / 増殖 / 分化 / 転写因子 / サイトカインセプター / developmental engineering / Monoclonal antibody / diagnostic antigens / gene engineering / recombinant antigen / cytokine knock-out mice / protective immunity / Babesia parasites / 防御抗原 / ELISA / イヌバベシア / ウマバベシア / マウスバベシア / モノクローナル抗体 / 診断用抗原 / リコンビナント抗原 / 防御免疫 / サイトカインノックアウトマウス / mouse / Trypanosoma / Babesia / Interferon / Scavenger receptor / macrophage / Transgenic / ネオスポーラ原虫 / インターフエロン / 遺伝子導入 / トリパノソーマ原虫 / インターフェロン / スカベンジャー受容体 / マクロファージ / Gonad / Implantation / Fertilization / Embryo differentiation / Embryo manipulation / Reproduction / Gene targetting / Transgenic animal / トランスジェニック動物 / 性腺 / 着床 / 胚分化 / 初期胚操作 / 生殖 / ジーンターゲティング / embryo freezing / c-mos / PCR / 性比 / 初期発生 / c-mos遺伝子 / 遺伝子ターゲット法 / 胚の凍結保存 / c-mos 遺伝子 / 遺伝子ターゲット / adenovirus / cyclin / ベータガラクトシダーゼ / メタロチオネイン / 顕微注入 / レポーター遺伝子 / 性判別 / 性分化 / アデノウイルスベクター / エンドセリン / サイクリン / チミヂンキナーゼ遺伝子 / グロビン / F9細胞 / 胚の分化と増殖 / 胚割球の分離 / 体外培養 / カニクイザル / 染色体外環状DNA / TNF / HIV-1 tatIII / HTLV-1 tax-1 / 生殖系列 / 人小細胞肺癌 / ヒト成人性T細胞白血病 / DNAートランスフェクション / pXーII遺伝子 / HTLVーII / pXーI遺伝子 / HTLVー / 腫瘍遺伝子 / 細胞工学方法 / 核移植細胞 / テラトカルシノーマ / リガンド / DCIR / C型レクチン受容体 / レクチン / 骨代謝 / 細菌感染 / 真菌感染防御 / サイトカイン / 疾患モデルマウス / Th17 / T細胞 / 肥満 / インスリン / 脂肪細胞 / siRNA / データベース / 再プログラム化 / Nanog / 4 / Oct-3 / 多能性 / 神経幹細部 / 遺伝子 / 発生・分化 / 再生医学 / 遅延型接触過敏症反応 / 胎生致死 / 成長遅延 / 分子進化 / cDNA突然変異誘発法 / 白血病抑制因子 / 胎盤性ラクトジェン / 絨毛性性腺刺激ホルモン / 糖鎖 / 血球分化 / 造血幹細胞 / MDS / 白血病 / 変異G-CSFR / Kostmann症候群 / G-CSF受容体(G-CSFR) / チロシンキナーゼ / ネコ免疫不全ウィルス / サル免疫不全ウィルス / ヒト免疫不全ウィルス / 後天性免疫不全症 / ヒト免疫不全ウイルス / スキッドマウス / キメラウイルス / 癌抑制遺伝子 / 動物モデル / エイズ / 組換えウイルス / HTLVI / トランスサイレチン / 遺伝子欠損モデル / 胚幹細胞 / ジーンターゲッティング / 遺伝子治療 / 遺伝子診断 / 病因変異 / 遺伝子単離 / 分子生物学 / 単一遺伝子病 / 癌抑制院伝子 / 相同的組替え / 核移植 / 遺伝子導入動物 / 胚奇形腫 / 始原生植細胞 / 高脂血症 / 高血圧 / 標的遺伝子置換法 / ジ-ンタ-ゲッティング / モデル動物 / 分化遺伝子 / ウシ / サル / テラト-マ / キメラ / ジ-ンタ-ゲッティング法 / 高血圧症モデル / 家族性アミロイドニュ-ロパシ- / インターフェロン遺伝子 / 成長ホルモン遺伝子 / 共培養 / 遺伝子標的導入法 / アンチセンス / 家族性アミロイドポリニューロパチー / vーmos / cーfos / HIVーtatIII遺伝子 / HTLVーI taxー1遺伝子 Less
  • Research Projects

    (104 results)
  • Research Products

    (795 results)
  • Co-Researchers

    (192 People)
  •  腎尿細管間質病変の進行における CTRP6-PAQR シグナル伝達経路の役割

    • Principal Investigator
      紀 熙華
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tokyo University of Science
  •  Mechanisms of autoimmunity induced by excess IL-1 signalingPrincipal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      The University of Tokyo
  •  Functional analysis of CTRP3, CTRP6 and their receptors using gene targeted micePrincipal Investigator

    • Principal Investigator
      Iwakura Yoichiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      The University of Tokyo
      Tokyo University of Science
  •  Analysis of inflammation, allergy, fibrosis, and tumorigenesis through the innate immune systemPrincipal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tokyo University of Science
  •  Generation of gene-modified mice by targeting on innate immune receptor family and analysis of the function of these receptors by using human disease-models.

    • Principal Investigator
      TANG CE
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Tokyo University of Science
  •  真菌感染現象における抑制型C型レクチン受容体の生理機能の解明

    • Principal Investigator
      矢部 力朗
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Chiba University
  •  自然免疫受容体を介した腸管免疫の制御と全身免疫への影響の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Tokyo University of Science
  •  Analysis of physiological function of C-type lectin receptor and application to disease controlPrincipal Investigator

    • Principal Investigator
      Iwakura Yoichiro
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Tokyo University of Science
  •  Elucidation of the host's homeostatic responses by the regulation of immune system and its application to the prevention and treatment of immunological disorders

    • Principal Investigator
      Taniguchi Tadatsugu
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Anti-fungal Immunity

    • Principal Investigator
      Saijo Shinobu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including mycology)
    • Research Institution
      Chiba University
  •  The physiological functions of a C-type lectin receptor and the relation with diseases

    • Principal Investigator
      KAIFU Tomonori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tohoku Medical and Pharmaceutical University
      Tokyo University of Science
  •  Establishment of an IL-1-related gene-manipulated mouse library and dissection of the gene-targeted mice, aiming at identifying new therapeutic targets for diseasesPrincipal Investigator

    • Principal Investigator
      Iwakura Yoichiro
    • Project Period (FY)
      2012 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo University of Science
  •  創薬標的の探索を目指したIL-1関連遺伝子改変マウスライブラリーの作製研究Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo University of Science
  •  The role of C-type lectins in the host defense against fungal infections

    • Principal Investigator
      SAIJO Shinobu
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Chiba University
  •  Establishing a new animal model for ankylosing spondylolysis using DCIR deficient mice

    • Principal Investigator
      KAIFU Tomonori
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo University of Science
      The University of Tokyo
  •  真菌感染防御におけるC型レクチンの役割

    • Principal Investigator
      西城 忍
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Chiba University
      The University of Tokyo
  •  炎症性サイトカインとC型レクチンによる発がん制御機構の解析

    • Principal Investigator
      角田 茂
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Establishment of an IL-1-related gene-manipulated mice library, aiming at uncovering pathophysiology of disease from a view point of systems biologyPrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  疾患のシステム的理解を目指したIL-1関連遺伝子欠損マウスライブラリーの作製Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  インターロイキン17/17Fによる細菌感染防御機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  The roles of cytokines in the development of autoimmune deseasesPrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  骨・軟骨の恒常性維持におけるケモカイン及びC型レクチンの役割の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  脂肪細胞から分泌されるlL-1Raの役割

    • Principal Investigator
      千田 大
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  自己免疫性関節炎発症における樹状細胞の役割Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Roles of dendritic cells in the development of autoimmune arthropathyPrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Analysis of genes involved in the pathogenesis of the arthritis using animal disease models..

    • Principal Investigator
      SAIJO Shinobu
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  関節リウマチの遺伝的要因の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  自己免疫性関節炎発症における樹状細胞の役割Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  慢性関節リウマチの遺伝的要因の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  体細胞初期化誘導および未分化維持に関するシグナル因子の解析

    • Principal Investigator
      角田 茂, 須藤 カツ子
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Interplay between TLR-mediated innate immunity, acquired immunity and in Toxoplasma gondii-derived heat shock protein, TgHSP70, in toxoplasmosis

    • Principal Investigator
      YANO Akihiko
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Chiba University
  •  疾患モデルマウスを用いた関節リウマチの遺伝的要因の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  cDNA microarray analysis of toxoplasmic retinochoroiditis

    • Principal Investigator
      NOROSE Kazumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Chiba University
  •  IL-1による免疫応答制御機構の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  関節リウマチの遺伝要因の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  インターフェロン・サイトカインの抗癌作用の研究Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HTLV-Iによる自己免疫性慢性関節炎発症機構の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  A STUDY ON THE CONTROL OF BONE DESTRUCTION USING OSTEOCLAST DIFFERENTIATION FACTOR AS A TARGET

    • Principal Investigator
      YASUDA Hisataka
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Establishment of ES cell lines derived from several inbred strains

    • Principal Investigator
      SUDO Katsuko
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  IL-1による免疫応答制御機構の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  関節リウマチの遺伝要因の解明Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  インターフェロン・サイトカインの抗癌作用の研究Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  The roles of cytokines on the development of rheumatoid arthritisPrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Establishment of in-house cDNA microarray for analysis of pathogenicity of Toxoplasma gondii infection and developing methods of diagnosis and therapy for toxoplasmosis

    • Principal Investigator
      YANO Akihiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      寄生虫学(含医用動物学)
    • Research Institution
      Chiba University
  •  Regulation Mechanisms of HIV LTR Demethylation through Reactivation Signaling

    • Principal Investigator
      ISHIDA Takaomi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  Effect of Heart Shock Protein and Interferon on Toxoplasmic Chorioretinitis

    • Principal Investigator
      NOROSE Kazumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      CHIBA UNIVERSITY
  •  インターフェロン・サイトカインの抗癌作用の研究Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kanazawa University
  •  発生工学的手法によるエイズ制圧の試みPrincipal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  発生工学的手法を用いたケモカインによる造血分化決定機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Production and Analysis of TAG-1 Knockout Mouse

    • Principal Investigator
      FUKAMAUCHI Fumihiko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Tokyo Medical and Dental University
  •  Generation and analysis of NB-3 deficient mice

    • Principal Investigator
      WATANABE Kazutada
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Tokyo Metropolitan Institute of Gerontology
  •  A trial to generate recipient mice which support the development of human hematopoietic stem cells to T-lymphocytes

    • Principal Investigator
      SUDO Katsuko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  ガラクトース転移酵素遺伝子ノックアウトマウスを用いた糖鎖機能の解析

    • Principal Investigator
      浅野 雅秀
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  発生工学的手法によるエイズ制圧の試みPrincipal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Basic Research for AIDS control A03 ; Prevention and control of AIDS

    • Principal Investigator
      MATSUSHITA Shuzo
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Development of rheumatoid arthritis models using transgenic techniquePrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  Functional analysis of IL-1 in immune and stress responses using gene knockout mice

    • Principal Investigator
      ASANO Masahide
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University
      The University of Tokyo
  •  インターフェロンによるアポトーシスの誘導と発がん抑制Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒトG-CSFレセプタートランスジェニックマウスを用いた白血病発症機構の研究

    • Principal Investigator
      中畑 龍俊
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒト細胞白血病ウィルスによる自己免疫症機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  糖鎖による情報積載の分子発達:糖タンパク質の機能と構造

    • Principal Investigator
      小川 智也
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  Analysis on protective antigen of Babesia parasites by developmental engineering

    • Principal Investigator
      IGARASHI Ikuo
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Applied veterinary science
    • Research Institution
      Obihiro University Agriculture and Veterinary Medicine
  •  Activation of cytokine signaling by constitutively active STAT5.

    • Principal Investigator
      KITAMURA Toshio
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  ジーンターゲティングによるコンタクチン遺伝子欠損マウスの作製と解析

    • Principal Investigator
      FUKAMAUCHI Fumihiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Tokyo Medical and Dental University
  •  標的遺伝子組み換え法によるサイトカインの炎症反応における役割の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ヒトT細胞白血病ウイルスによる自己免疫発症機構の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Deveropmental biotechnological analysis of host defense mechanisms against protozoan infection

    • Principal Investigator
      TOYODA Yutaka
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied veterinary science
    • Research Institution
      OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE
  •  サイトカイン研究のための遺伝子改変マウスライブラリーの作製Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  標的遺伝子組み換え法を用いたサイトカインの生理機能の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  エイズの病態と制御に関する基礎研究 エイズの動物モデル

    • Principal Investigator
      速水 正憲
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  遺伝子導入マウスのコンピューターによる維持・管理システムの開発Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      The University of Tokyo
  •  単一遺伝子病の分子・細胞生物学的研究

    • Principal Investigator
      多田 啓也, 勝木 元也
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
      Kyushu University
  •  エイズ制圧に向けての基礎研究・エイズの動物モデル

    • Principal Investigator
      速水 正憲
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  標的遺伝子組換え法を用いたサイトカインの生理機能の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  遺伝子導入動物による発癌の研究

    • Principal Investigator
      樋野 興夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  遺伝子導入動物による発症の研究

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  トランスジェニックマウスを用いたインターフェロンの癌抑制作用の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  成人T細胞白血病ウイルスによる自己免疫状態の誘導機構に関する研究Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  標的遺伝子組換え法を用いたサイトカインの生理機能の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Biotechnological studies on the mechanisms regulating embryogenesis

    • Principal Investigator
      TOYODA Yutaka
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Applied animal science
    • Research Institution
      The University of Tokyo
  •  Analysis of reproductive processes by means of transgenic animals

    • Principal Investigator
      TAKAHASHI Michio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Basic veterinary science/Basic zootechnical science
    • Research Institution
      The University of Tokyo
  •  遺伝子導入動物による発癌の研究

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  遺伝子破壊法によるインターフェロンの癌抑制機能の解析Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Studies on te regulatory mechanisms of gene expression in early embryos

    • Principal Investigator
      TOYODA Yutaka
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      畜産学(含草地学)
    • Research Institution
      The University of Tokyo
  •  Pathogenesis of inflammatory arthropathy developed in HTLV-I transgenic micePrincipal Investigator

    • Principal Investigator
      IWAKURA Yoichiro
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  遺伝子導入動物による発癌の研究

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  初期発生における割球分化の分子機構

    • Principal Investigator
      入谷 明
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  初期発生における割球分化の分子機構

    • Principal Investigator
      入谷 明
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  発癌遺伝子移入による正常造血系細胞のimmortalization

    • Principal Investigator
      関口 豊三
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kohno Clinical Medicine Research Institute
  •  初期発生の分子機構

    • Principal Investigator
      入谷 明
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  発癌遺伝子移入による正常造血系細胞のimmortalzation

    • Principal Investigator
      関口 豊三
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kohno Clinical Medicine Research Institute
  •  個体レベルにおける各種インターフェロンの生物活性の検討Principal Investigator

    • Principal Investigator
      岩倉 洋一郎
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      The University of Tokyo
  •  初期発生の分子機構

    • Principal Investigator
      入谷 明
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyoto University
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  発癌遺伝子の移入による正常造血系細胞のImmortalizationと癌化

    • Principal Investigator
      関口 豊三
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  生殖系列の分子機構に関する基礎研究

    • Principal Investigator
      毛利 秀雄
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      The University of Tokyo
  •  細胞工学方法によるテラトカルシノーマの分化誘導と腫瘍遺伝子発現の制御

    • Principal Investigator
      関口 豊三
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent Other

  • [Book] 消化器外科 2020年1月号 「癌と炎症を学ぶ 解説1 IL-17,Th17」2020

    • Author(s)
      唐策、岩倉洋一郎
    • Total Pages
      128
    • Publisher
      へるす出版
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Book] EXPERT膠原病・リウマチ 改訂第4版2019

    • Author(s)
      20.角田茂、岩倉洋一郎
    • Total Pages
      416
    • Publisher
      診断と治療社
    • ISBN
      9784787823830
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] 医学のあゆみ 食品成分による腸管Tregの制御2019

    • Author(s)
      岩倉洋一郎
    • Total Pages
      264
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Book] 医学のあゆみ IL-17ファミリー分子の生体における役割2019

    • Author(s)
      岩倉洋一郎
    • Total Pages
      120
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Book] トピックス 「自己免疫疾患に対する新たな治療標的の発見」2017

    • Author(s)
      村山正承、岩倉洋一郎
    • Total Pages
      4
    • Publisher
      理大科学フォーラム
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] トピックス 「自己免疫疾患に対する新たな治療標的の発見」2017

    • Author(s)
      村山正承、岩倉洋一郎
    • Total Pages
      4
    • Publisher
      理大科学フォーラム
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] セミナー室「低分子βグルカン摂取により炎症性腸疾患を予防,改善する」2016

    • Author(s)
      唐策、角田茂、岩倉洋一郎
    • Total Pages
      6
    • Publisher
      日本農芸化学会
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] セミナー室「低分子βグルカン摂取により炎症性腸疾患を予防,改善する」2016

    • Author(s)
      唐策、角田茂、岩倉洋一郎
    • Total Pages
      6
    • Publisher
      日本農芸化学会
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] IL-1ファミリー分子による免疫制御2016

    • Author(s)
      秋津葵、岩倉洋一郎
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016

    • Author(s)
      Tomonori Kaifu and Yoichiro Iwakura.
    • Total Pages
      12
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 自己免疫性関節炎と病原性T細胞2016

    • Author(s)
      秋津葵、岩倉洋一郎
    • Total Pages
      5
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] 医歯薬出版株式会社2016

    • Author(s)
      秋津葵、岩倉洋一郎
    • Total Pages
      5
    • Publisher
      自己免疫性関節炎と病原性T細胞
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] Dendritic Cell Immunoreceptor (DCIR): An ITIM-Harboring C-Type Lectin Receptor.2016

    • Author(s)
      Tomonori Kaifu and Yoichiro Iwakura.
    • Total Pages
      12
    • Publisher
      Springer Japan
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Book] IL-1ファミリー分子による免疫制御2016

    • Author(s)
      秋津葵、岩倉洋一郎
    • Total Pages
      7
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-18/33/36/37」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      海部知則、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「成長ホルモン」「プロラクチン」サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      米沢朋、丸田大貴、岩倉洋一郎
    • Total Pages
      5
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-12」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      矢部力朗、岩倉洋一郎
    • Total Pages
      2
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-19/20/22/24/26」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      神谷知憲、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-14」「IL-16」「IL-32」サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      村山正承、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-17A/17B/17C/17D/17E/17F」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      秋津葵、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] Current Topics. デクチン1シグナルの阻害は、腸内乳酸桿菌を増殖させ、制御性T細胞を増加させることによって、大腸炎を抑制する」実験医学20162015

    • Author(s)
      唐策、岩倉洋一郎
    • Total Pages
      4
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-23/35」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      唐策、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 【大学発 日本 人と技術】日本を支える研究活動と技術開発 関節リウマチの新たな治療薬開発2015

    • Author(s)
      村山正承、岩倉洋一郎
    • Total Pages
      1
    • Publisher
      フジサンケイビジネスアイ
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第2章 インターフェロン「概論」「IFN-α/β」「IFN-γ」「IFN-λファミリー(IL-28, IL-29)」サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      角田茂、岩倉洋一郎
    • Total Pages
      10
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-10」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      鄭琇絢、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 第1章 インターロイキン「IL-1」 サイトカイン・増殖因子キーワード事典2015

    • Author(s)
      清水謙次、岩倉洋一郎
    • Total Pages
      3
    • Publisher
      洋土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 実験医学増刊、炎症―全体像を知り慢性炎症を制御するー2014

    • Author(s)
      矢部力朗、岩倉洋一郎、西城忍
    • Total Pages
      219
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] サイトカインと自己免疫疾患.EXPERT膠原病・リウマチ 改訂第3版(住田孝之編)2013

    • Author(s)
      角田茂、岩倉洋一郎
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Book] 炎症性サイトカインと骨破壊2012

    • Author(s)
      海部知則, 岩倉洋一郎
    • Publisher
      医学のあゆみ
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Book] 遺伝子改変動物.新しい薬学事典2012

    • Author(s)
      角田茂、岩倉洋一郎
    • Publisher
      朝倉書店(印刷中)
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] IL-1. seriesモデル動物利用マニュアル 免疫疾患-疾患モデルの作製と利用2011

    • Author(s)
      角田茂、岩倉洋一郎
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] 免疫疾患.疾患モデルの作製と利用.シリーズ「モデル動物利用マニュアル」2011

    • Author(s)
      岩倉洋一郎
    • Total Pages
      580
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] 発刊にあたって.免疫疾患-疾患モデルの作製と利用.シリーズモデル動物利用マニュアル2011

    • Author(s)
      岩倉洋一郎
    • Total Pages
      580
    • Publisher
      エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] 遺伝子改変マウス."哺乳動物の分子生物学"を切り拓いた技術バイオテクノロジーの温故知新2011

    • Author(s)
      岩倉洋一郎
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] アグリゲーション法によるキメラマウスの作製.改訂第5版新遺伝子工学ハンドブック2010

    • Author(s)
      角田茂、佐藤希、久保幸子、岩倉洋一郎
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] Dcirと自己免疫疾患最新医学2009

    • Author(s)
      藤門範行、岩倉洋一郎
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] サイトカインシグナルと代謝疾患2008

    • Author(s)
      千田大、岩倉洋一郎
    • Publisher
      ニュー・サイエンス社
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Book] nterleukin-1 deficiency and aggressiveness in male mice.(M.T. Czerbnska ed., Psychoneuroendocrinology Research Trends)2007

    • Author(s)
      Tamagawa, A., Kolosova, I., Endo, Y., Gerlinskaya, L., Iwakura, Y., Moshikin, M.
    • Publisher
      Nova Science Publishers, Inc.
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Book] The roles of IL-17A and IL-17F in mucosal infection and allergy.(ed. S. Jiang, Th17 cells in health and disease)

    • Author(s)
      Ishigame, H., Nakae, S., Iwakura, Y.
    • Publisher
      Springer Science + Buisiness(in press)
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding protein expression2023

    • Author(s)
      Tang Ce、Sun Haiyang、Kadoki Motohiko、Han Wei、Ye Xiaoqi、Makusheva Yulia、Deng Jianping、Feng Bingbing、Qiu Ding、Tan Ying、Wang Xinying、Guo Zehao、Huang Chanyan、Peng Sui、Chen Minhu、Adachi Yoshiyuki、Ohno Naohito、Trombetta Sergio、Iwakura Yoichiro
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 1-21

    • DOI

      10.1038/s41467-023-37229-x

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Interleukin-6 regulates the expression of hepatic canalicular efflux drug transporters after cecal ligation and puncture-induced sepsis: A comparison with lipopolysaccharide treatment2023

    • Author(s)
      Takashi Ashino, Yuki Nakamura, Hirokazu Ohtaki, Yoichiro Iwakura, Satoshi Numazawa
    • Journal Title

      Toxicology Letters

      Volume: 374 Pages: 40-47

    • DOI

      10.1016/j.toxlet.2022.12.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K08136, KAKENHI-PROJECT-22K09317, KAKENHI-PROJECT-22K19737, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-23K21623
  • [Journal Article] Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays2022

    • Author(s)
      Lee Suyoung、Byun Seohyun、Lee Changhon、Park Sun Hee、Rudra Dipayan、Iwakura Yoichiro、Lee You Jeong、Im Sin‐Hyeog、Hwang Dong Soo
    • Journal Title

      Advanced Healthcare Materials

      Volume: 11 Issue: 13 Pages: 2102667-2102667

    • DOI

      10.1002/adhm.202102667

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Dermal Vγ6+ γδ T17 Cells are Involved in Skin Pressure Ulcers in Mice2022

    • Author(s)
      Mine Keiichiro、Tun Xin、Hatano Shinya、Noguchi Naoto、Iwakura Yoichiro、Sawa Shinichiro、Nagafuchi Seiho、Yoshikai Yasunobu
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 7 Issue: 8 Pages: 00002-00002

    • DOI

      10.1016/j.jid.2021.12.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-22K16428, KAKENHI-PROJECT-19H03483, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21K19486
  • [Journal Article] An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity2022

    • Author(s)
      Borriello Francesco、Poli Valentina、Shrock Ellen、Spreafico Roberto、Liu Xin、Pishesha Novalia、Carpenet Claire、Chou Janet、Di Gioia Marco、McGrath Marisa E.、Dillen Carly A.、Barrett Nora A.、Lacanfora Lucrezia、Franco Marcella E.、Marongiu Laura、Iwakura Yoichiro、Pucci Ferdinando、Kruppa Michael D.、et al
    • Journal Title

      Cell

      Volume: 185 Issue: 4 Pages: 614-629.e21

    • DOI

      10.1016/j.cell.2022.01.009

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Reactive granulopoiesis depends on T-cell production of IL-17A and neutropenia-associated alteration of gut microbiota2022

    • Author(s)
      Chen Xuanzhong、Hashimoto Daigo、Ebata Ko、Takahashi Shuichiro、Shimizu Yu、Shinozaki Ryuga、Hasegawa Yuta、Kikuchi Ryo、Senjo Hajime、Yoneda Kazuki、Zhang Zixuan、Harada Shinpei、Hayase Eiko、Ara Takahide、Ohigashi Hiroyuki、Iwakura Yoichiro、Nakamura Kiminori、Ayabe Tokiyoshi、Teshima Takanori
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 48 Pages: 1-10

    • DOI

      10.1073/pnas.2211230119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K08409, KAKENHI-PROJECT-22K19120, KAKENHI-PROJECT-21K16259, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H04098, KAKENHI-PROJECT-21H02891, KAKENHI-PROJECT-22KJ0033, KAKENHI-PROJECT-20K21610, KAKENHI-PROJECT-22K16009, KAKENHI-PROJECT-23K21439
  • [Journal Article] Heat-Killed Levilactobacillus brevis as a Candidate Postbiotics Through Immunostimulation Mediated by Macrophage-Inducible C-Type Lectin2022

    • Author(s)
      Shimazu Tomoyuki、Suzuki Mai、Takasaki Ryo、Besshi Asuka、Suzuki Yuna、Iwakura Yoichiro
    • Journal Title

      Probiotics and Antimicrobial Proteins

      Volume: 1 Issue: 3 Pages: 1-10

    • DOI

      10.1007/s12602-021-09890-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] The C-type lectin receptor Clec1A plays an important role in the development of experimental autoimmune encephalomyelitis by enhancing antigen presenting ability of dendritic cells and inducing inflammatory cytokine IL-172022

    • Author(s)
      MAKUSHEVA Yulia、CHUNG Soo-Hyun、AKITSU Aoi、MAEDA Natsumi、MARUHASHI Takumi、YE Xiao-Qi、KAIFU Tomonori、SAIJO Shinobu、SUN Haiyang、HAN Wei、TANG Ce、IWAKURA Yoichiro
    • Journal Title

      Exp. Anim.

      Volume: 71 Issue: 3 Pages: 288-304

    • DOI

      10.1538/expanim.21-0191

    • NAID

      130008158392

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21J01492, KAKENHI-PROJECT-21K07063, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K06471
  • [Journal Article] mTORC1 links pathology in experimental models of Still’s disease and macrophage activation syndrome2022

    • Author(s)
      Huang Zhengping,You Xiaomeng,Chen Liang,Du Yan,Brodeur Kailey,Jee Hyuk,Wang Qiang,Linder Grace,Darbousset Roxane,Cunin Pierre,Chang Margaret H.,Wactor Alexandra,Wauford Brian M.,Todd Marc J. C.,Wei Kevin,Li Ying,Levescot Anais,Iwakura Yoichiro,et al.
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41467-022-34480-6

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Human Dectin-1 deficiency impairs macrophage-mediated defense against phaeohyphomycosis2022

    • Author(s)
      Drummond Rebecca A.,Desai Jigar V.,Hsu Amy P.,Oikonomou Vasileios,Vinh Donald C.,Acklin Joshua A.,Abers Michael S.,Walkiewicz Magdalena A.,Anzick Sarah L.,Swamydas Muthulekha、Vautier Simon,Natarajan Mukil,Oler Andrew J.,Yamanaka Daisuke,Mayer-Barber Katrin D.,Iwakura Yoichiro,et al.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 132 Issue: 22 Pages: 1-13

    • DOI

      10.1172/jci159348

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Intestinal commensal microbiota and cytokines regulate Fut2 <sup>+</sup> Paneth cells for gut defense2022

    • Author(s)
      Kamioka Mariko、Goto Yoshiyuki、Nakamura Kiminori、Yokoi Yuki、Sugimoto Rina、Ohira Shuya、Kurashima Yosuke、Umemoto Shingo、Sato Shintaro、Kunisawa Jun、Takahashi Yu、Domino Steven E.、Renauld Jean-Christophe、Nakae Susumu、Iwakura Yoichiro、Ernst Peter B.、Ayabe Tokiyoshi、Kiyono Hiroshi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 119 Issue: 3 Pages: 1-10

    • DOI

      10.1073/pnas.2115230119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H04098, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21H02891, KAKENHI-PROJECT-21H02963, KAKENHI-PROJECT-20J11528, KAKENHI-PROJECT-21K15460, KAKENHI-PROJECT-21K19494, KAKENHI-PROJECT-19K17452, KAKENHI-PROJECT-18H05280
  • [Journal Article] Resolving the Mutually Exclusive Immune Responses of Chitosan with Nanomechanics and Immunological Assays2022

    • Author(s)
      Lee S, Byun S, Lee C, Park SH, Rudra D, Iwakura Y, Lee YJ, Im SH, Hwang DS.
    • Journal Title

      Advanced healthcare materials

      Volume: 9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02394
  • [Journal Article] ⑤Arteriosclerosis Derived from Cutaneous Inflammation Is Ameliorated by the Deletion of IL-17A and IL-17F.2022

    • Author(s)
      Nakanishi T, Iida S, Maruyama J, Urushima H, Ichishi M, Matsushima Y, Mizutani K, Nakayama Y, Sugioka K, Nishimura M, Umaoka A, Iwakura Y, Kondo M, Habe K, Tsuruta D, Yamamoto O, Imai Y, Yamanaka K
    • Journal Title

      Int J Mol Sci

      Volume: 24(6) Issue: 6 Pages: 5434-5434

    • DOI

      10.3390/ijms24065434

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16226, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-22K08379
  • [Journal Article] Epidermal clearance of <i>Candida albicans</i> is mediated by IL-17 but independent of fungal innate immune receptors2022

    • Author(s)
      Iwasawa Mari T、Miyachi Hideaki、Wakabayashi Seiichiro、Sugihira Takashi、Aoyama Reika、Nakagawa Seitaro、Katayama Yuki、Yoneyama Mitsutoshi、Hara Hiromitsu、Iwakura Yoichiro、Matsumoto Masanori、Inohara Naohiro、Koguchi-Yoshioka Hanako、Fujimoto Manabu、N??ez Gabriel、Matsue Hiroyuki、Nakamura Yuumi、Saijo Shinobu
    • Journal Title

      International Immunology

      Volume: 34 Issue: 8 Pages: 409-420

    • DOI

      10.1093/intimm/dxac019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07063, KAKENHI-PROJECT-21K08294, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03701
  • [Journal Article] USP10 Inhibits Aberrant Cytoplasmic Aggregation of TDP-43 by Promoting Stress Granule Clearance2022

    • Author(s)
      Takahashi Masahiko、Kitaura Hiroki、Kakita Akiyoshi、Kakihana Taichi、Katsuragi Yoshinori、Onodera Osamu、Iwakura Yuriko、Nawa Hiroyuki、Komatsu Masaaki、Fujii Masahiro
    • Journal Title

      Molecular and Cellular Biology

      Volume: 42 Issue: 3

    • DOI

      10.1128/mcb.00393-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-21H04771, KAKENHI-PROJECT-19H03432, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K07291, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K07757, KAKENHI-PROJECT-19H03542
  • [Journal Article] Blocking DCIR mitigates colitis and prevents colorectal tumors by enhancing the GM-CSF-STAT5 pathway2022

    • Author(s)
      Sun Haiyang、Tang Ce、Chung Soo-Hyun、Ye Xiao-Qi、Makusheva Yulia、Han Wei、Kubo Masato、Shichino Shigeyuki、Ueha Satoshi、Matsushima Koji、Ikeo Kazuho、Asano Masahide、Iwakura Yoichiro
    • Journal Title

      Cell Reports

      Volume: 40 Issue: 5 Pages: 111158-111158

    • DOI

      10.1016/j.celrep.2022.111158

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03474, KAKENHI-WRAPUP-22H04906
  • [Journal Article] Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model2022

    • Author(s)
      Jonckheere Anne-Charlotte、Seys Sven F.、Steelant Brecht、Decaesteker Tatjana、Dekoster Kaat、Cremer Jonathan、Dilissen Ellen、Schols Dominique、Iwakura Yoichiro、Vande Velde Greetje、Breynaert Christine、Schrijvers Rik、Vanoirbeek Jeroen、Ceuppens Jan L.、Dupont Lieven J.、Bullens Dominique M. A.
    • Journal Title

      Frontiers in Immunology

      Volume: 13 Pages: 1-10

    • DOI

      10.3389/fimmu.2022.849155

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] IL-17A Is the Critical Cytokine for Liver and Spleen Amyloidosis in Inflammatory Skin Disease2022

    • Author(s)
      Iida S, Nakanishi T, Momose F, Ichishi M, Mizutani K, Matsushima Y, Umaoka A, Kondo M, Habe K, Hirokawa Y, Watanabe M, Iwakura Y, Miyahara Y, Imai Y, Yamanaka K.
    • Journal Title

      Int J Mol Sci .

      Volume: 23 Issue: 10 Pages: 5726-5726

    • DOI

      10.3390/ijms23105726

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08379, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-23K24180
  • [Journal Article] <i>Plap-1</i> lineage tracing and single-cell transcriptomics reveal cellular dynamics in the periodontal ligament2022

    • Author(s)
      Iwayama Tomoaki、Iwashita Mizuho、Miyashita Kazuya、Sakashita Hiromi、Matsumoto Shuji、Tomita Kiwako、Bhongsatiern Phan、Kitayama Tomomi、Ikegami Kentaro、Shimbo Takashi、Tamai Katsuto、Murayama Masanori A.、Ogawa Shuhei、Iwakura Yoichiro、Yamada Satoru、Olson Lorin E.、Takedachi Masahide、Murakami Shinya
    • Journal Title

      Development

      Volume: 149 Issue: 19 Pages: 201203-201203

    • DOI

      10.1242/dev.201203

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06955, KAKENHI-PROJECT-21K16991, KAKENHI-PROJECT-19H01069, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-23K24527
  • [Journal Article] Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome2021

    • Author(s)
      Yamada Ayumi、Hirasawa Takae、Nishimura Kayako、Shimura Chikako、Kogo Naomi、Fukuda Kei、Kato Madoka、Yokomori Masaki、Hayashi Tetsutaro、Umeda Mana、Yoshimura Mika、Iwakura Yoichiro、Nikaido Itoshi、Itohara Shigeyoshi、Shinkai Yoichi
    • Journal Title

      iScience

      Volume: 24 Issue: 7 Pages: 102741-102741

    • DOI

      10.1016/j.isci.2021.102741

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-18H05530, KAKENHI-PROJECT-18H03991, KAKENHI-PROJECT-21H02394
  • [Journal Article] Dual interleukin-17A/F deficiency protects against acute and chronic response to cigarette smoke exposure in mice2021

    • Author(s)
      Wada Hiroo、Nakamura Masuo、Inoue Shin-Ichi、Kudo Akihiko、Hanawa Tomoko、Iwakura Yoichiro、Kobayashi Fumie、Kamma Hiroshi、Kamiya Shigeru、Ito Kazuhiro、Barnes Peter J.、Takizawa Hajime
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-021-90853-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Interleukin-17 family members in health and disease2021

    • Author(s)
      Chung Soo-Hyun、Ye Xiao-Qi、Iwakura Yoichiro
    • Journal Title

      International Immunology

      Volume: 33 Issue: 12 Pages: 723-729

    • DOI

      10.1093/intimm/dxab075

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Vγ6 + γδ T cells are critical for protection against infection by Escherichia coli in mice2021

    • Author(s)
      Tun Xin、Hatano Shinya、Mine Keiichiro、Noguchi Naoto、Iwakura Yoichiro、Sun Xun、Yoshikai Yasunobu
    • Journal Title

      European Journal of Immunology

      Volume: n/a Issue: 8 Pages: 2093-2096

    • DOI

      10.1002/eji.202049010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation2021

    • Author(s)
      Ito Y, Sasaki T, Li Y, et al
    • Journal Title

      Cell Reports

      Volume: 35 Issue: 4 Pages: 109052-109052

    • DOI

      10.1016/j.celrep.2021.109052

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H05627, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K08308
  • [Journal Article] Homeostatic regulation of T follicular helper and antibody response to particle antigens by IL-1Ra of medullary sinus macrophage origin2021

    • Author(s)
      Lin Xinwen、Twelkmeyer Trix、Zhu Danming、Zhang Li、Zhao Yang、Zhang Chao、Iwakura Yoichiro、Meng Guangxun、Hua Zhaolin、Yan Bingyu、Liu William J.、Luo Zhongguang、Gong Sitang、Chen Hairong、Li Shuran、Hou Baidong、Tang Hong
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 118 Issue: 17 Pages: 1-10

    • DOI

      10.1073/pnas.2019798118

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] DCIR and its ligand asialo-biantennary N-glycan regulate DC function and osteoclastogenesis2021

    • Author(s)
      Kaifu Tomonori、Yabe Rikio、Maruhashi Takumi、Chung Soo-Hyun、Tateno Hiroaki、Fujikado Noriyuki、Hirabayashi Jun、Iwakura Yoichiro
    • Journal Title

      Journal of Experimental Medicine

      Volume: 218 Issue: 12 Pages: 1-10

    • DOI

      10.1084/jem.20210435

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-19K06471
  • [Journal Article] Role of Dectin-2 in the Phagocytosis of Cryptococcus neoformans by Dendritic Cells2021

    • Author(s)
      Kitai Yuki、Sato Ko、Tanno Daiki、Yuan Xiaoliang、Umeki Aya、Kasamatsu Jun、Kanno Emi、Tanno Hiromasa、Hara Hiromitsu、Yamasaki Sho、Saijo Shinobu、Iwakura Yoichiro、Ishii Keiko、Kawakami Kazuyoshi
    • Journal Title

      Infection and Immunity

      Volume: 89 Issue: 10 Pages: 1-10

    • DOI

      10.1128/iai.00330-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00505, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21H02965, KAKENHI-PROJECT-21K07063, KAKENHI-PROJECT-21K16314
  • [Journal Article] Arthritis flares mediated by tissue-resident memory T cells in the joint2021

    • Author(s)
      Chang Margaret H.、Levescot Ana?s、Nelson-Maney Nathan、Blaustein Rachel B.、Winden Kellen D.、Morris Allyn、Wactor Alexandra、Balu Spoorthi、Grieshaber-Bouyer Ricardo、Wei Kevin、Henderson Lauren A.、Iwakura Yoichiro、Clark Rachael A.、Rao Deepak A.、Fuhlbrigge Robert C.、Nigrovic Peter A.
    • Journal Title

      Cell Reports

      Volume: 37 Issue: 4 Pages: 109902-109902

    • DOI

      10.1016/j.celrep.2021.109902

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities2021

    • Author(s)
      Lee Changhon、Verma Ravi、Byun Seohyun、Jeun Eun-Ji、Kim Gi-Cheon、Lee Suyoung、Kang Hye-Ji、Kim Chan Johng、Sharma Garima、Lahiri Abhishake、Paul Sandip、Kim Kwang Soon、Hwang Dong Soo、Iwakura Yoichiro、Speciale Immacolata、Molinaro Antonio、De Castro Cristina、Rudra Dipayan、Im Sin-Hyeog
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41467-021-23929-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Distinct Roles for Dectin-1 and Dectin-2 in Skin Wound Healing and Neutrophilic Inflammatory Responses2021

    • Author(s)
      Yamaguchi Kenji、Kanno Emi、Tanno Hiromasa、Sasaki Ayako、Kitai Yuki、Miura Takayuki、Takagi Naoyuki、Shoji Miki、Kasamatsu Jun、Sato Ko、Sato Yuka、Niiyama Momoko、Goto Yuka、Ishii Keiko、Imai Yoshimichi、Saijo Shinobu、Iwakura Yoichiro、Tachi Masahiro、Kawakami Kazuyoshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 141 Issue: 1 Pages: 164-176

    • DOI

      10.1016/j.jid.2020.04.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-19K19494, KAKENHI-PROJECT-19H03812, KAKENHI-PROJECT-21K07063
  • [Journal Article] TARM1 contributes to development of arthritis by activating dendritic cells through recognition of collagens2021

    • Author(s)
      Yabe Rikio、Chung Soo-Hyun、Murayama Masanori A.、Kubo Sachiko、Shimizu Kenji、Akahori Yukiko、Maruhashi Takumi、Seno Akimasa、Kaifu Tomonori、Saijo Shinobu、Iwakura Yoichiro
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 94-94

    • DOI

      10.1038/s41467-020-20307-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K20681, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K06465, KAKENHI-PROJECT-17K16229, KAKENHI-PROJECT-21K07063
  • [Journal Article] The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation2021

    • Author(s)
      Murayama Masanori A.、Chi Hsi-Hua、Matsuoka Mako、Ono Takahiro、Iwakura Yoichiro
    • Journal Title

      Frontiers in Immunology

      Volume: 12 Pages: 607346-607346

    • DOI

      10.3389/fimmu.2021.607346

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K20681, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K06955
  • [Journal Article] Arthritis flares mediated by tissue-resident memory T cells in the joint.2021

    • Author(s)
      Chang, M. H., Levescot, A., Nelson-Maney, N., Blaustein, R. B., Winden, K. D., Morris, A., Wactor, A. Balu, S., Grieshaber-Bouyer, R., Wei, K., Henderson, L. A., Iwakura, Y., Clark, R. A., Rao, D. A., Fuhlbrigge, R. C., and Nigrovic, P. A.
    • Journal Title

      Cell Rep.

      Volume: 37 Pages: 109902-109902

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H02394
  • [Journal Article] Blocking of interleukin-1 suppresses angiotensin II-induced renal injury2021

    • Author(s)
      Akita Koji、Isoda Kikuo、Ohtomo Fumie、Isobe Sarasa、Niida Tomiharu、Sato-Okabayashi Yayoi、Sano Motoaki、Shimada Kazunori、Iwakura Yoichiro、Minamino Tohru
    • Journal Title

      Clinical Science

      Volume: 135 Issue: 17 Pages: 2035-2048

    • DOI

      10.1042/cs20201406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-17K01470, KAKENHI-PROJECT-20K08433
  • [Journal Article] IL-1β-driven osteoclastogenic Tregs accelerate bone erosion in arthritis2021

    • Author(s)
      Levescot Anais、Chang Margaret H.、Schnell Julia、Nelson-Maney Nathan、Yan Jing、Mart?nez-Bonet Marta、Grieshaber-Bouyer Ricardo、Lee Pui Y.、Wei Kevin、Blaustein Rachel B.、Morris Allyn、Wactor Alexandra、Iwakura Yoichiro、Lederer James A.、Rao Deepak A.、Charles Julia F.、Nigrovic Peter A.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 131 Issue: 18 Pages: 1-10

    • DOI

      10.1172/jci141008

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Obesity accelerates hair thinning by stem cell-centric converging mechanisms2021

    • Author(s)
      Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y,?Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK.
    • Journal Title

      Nature

      Volume: 595 Issue: 7866 Pages: 266-271

    • DOI

      10.1038/s41586-021-03624-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21621, KAKENHI-PROJECT-18K15114, KAKENHI-PROJECT-18H02637, KAKENHI-PUBLICLY-20H04944, KAKENHI-PUBLICLY-20H05503, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21H02957, KAKENHI-PROJECT-19K16607
  • [Journal Article] Derepression of inflammation-related genes link to microglia activation and neural maturation defect in a mouse model of Kleefstra syndrome2021

    • Author(s)
      Yamada Ayumi、Hirasawa Takae、Nishimura Kayako、Shimura Chikako、Kogo Naomi、Fukuda Kei、Kato Madoka、Yokomori Masaki、Hayashi Tetsutaro、Umeda Mana、Yoshimura Mika、Iwakura Yoichiro、Nikaido Itoshi、Itohara Shigeyoshi、Shinkai Yoichi
    • Journal Title

      iScience

      Volume: 24 Issue: 11 Pages: 103253-103253

    • DOI

      10.1016/j.isci.2021.103253

    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Journal Article] Ovalbumin-Induced Airway Inflammation Is Ameliorated in Dectin-1?Deficient Mice, in Which Pulmonary Regulatory T Cells Are Expanded through Modification of Intestinal Commensal Bacteria2021

    • Author(s)
      Han Wei、Tang Ce、Baba Seiya、Hamada Tomofumi、Shimazu Tomoyuki、Iwakura Yoichiro
    • Journal Title

      The Journal of Immunology

      Volume: 206 Issue: 9 Pages: 1991-2000

    • DOI

      10.4049/jimmunol.2001337

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] A Vaspin-HSPA1L complex protects proximal tubular cells from organelle stress in diabetic kidney disease2021

    • Author(s)
      Nakatsuka A, Yamaguchi S, Eguchi J, Kakuta S, Iwakura Y, Sugiyama H, Wada J.
    • Journal Title

      Commun Biol .

      Volume: 4 Issue: 1 Pages: 373-373

    • DOI

      10.1038/s42003-021-01902-y

    • NAID

      120007004153

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08608, KAKENHI-PROJECT-20K08908, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-19K17984, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K08679
  • [Journal Article] Effector memory CD4+T cells in mesenteric lymph nodes mediate bone loss in food-allergic enteropathy model mice, creating IL-4 dominance2021

    • Author(s)
      Ono-Ohmachi Aiko、Udagawa Nobuyuki、Nakamichi Yuko、Koide Masanori、Nakajima-Adachi Haruyo
    • Journal Title

      Mucosal Immunology

      Volume: 14 Issue: 6 Pages: 1335-1346

    • DOI

      10.1038/s41385-021-00434-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22729, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-20H03471, KAKENHI-PROJECT-20H03872, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-19K22728, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-21K16389, KAKENHI-PROJECT-19KK0234, KAKENHI-PROJECT-23K21488
  • [Journal Article] Immunomodulatory role of Parkinson’s disease 7 in inflammatory bowel disease2021

    • Author(s)
      Lippai Rita、Veres-Szekely Apor、Sziksz Erna、Iwakura Yoichiro、Pap Domonkos、Rokonay R?ka、Szebeni Be?ta、Lotz G?bor、B?res N?ra J.、Cseh ?ron、Szab? Attila J.、Vannay ?d?m
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-021-93671-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor2021

    • Author(s)
      Yang Chunfu、Lei Lei、Collins John W. Marshall、Briones Michael、Ma Li、Sturdevant Gail L.、Su Hua、Kashyap Anuj K.、Dorward David、Bock Kevin W.、Moore Ian N.、Bonner Christine、Chen Chih-Yu、Martens Craig A.、Ricklefs Stacy、Yamamoto Masahiro、Takeda Kiyoshi、Iwakura Yoichiro、McClarty Grant、Caldwell Harlan D.
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41467-021-25749-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394
  • [Journal Article] Dectin-2-mediated initiation of immune responses caused by influenza virus hemagglutinin2021

    • Author(s)
      YAMAMOTO Hideki、TOMIYAMA Chikako、SATO Ko、KASAMATSU Jun、TAKANO Kazuki、UMEKI Aya、NAKAHATA Nana、MIYASAKA Tomomitsu、KANNO Emi、TANNO Hiromasa、YAMASAKI Sho、SAIJO Shinobu、IWAKURA Yoichiro、ISHII Keiko、KAWAKAMI Kazuyoshi
    • Journal Title

      Biomed. Res.

      Volume: 42 Issue: 2 Pages: 53-66

    • DOI

      10.2220/biomedres.42.53

    • NAID

      130008023686

    • ISSN
      0388-6107, 1880-313X
    • Year and Date
      2021-04-10
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20K17461, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-21K07063
  • [Journal Article] TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.2021

    • Author(s)
      Koinuma, S., Negishi, R., Nomura, R., Sato, K., Kojima, T., Segi-Nishida, E., Goitsuka, R., Iwakura, Y., Wada, N., Koriyama, Y., Kiryu-Seo, S., Kiyama, H., and Nakamura, T. J.
    • Journal Title

      J. Neurochem.

      Volume: 157 Pages: 1196-1206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02394
  • [Journal Article] Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells2021

    • Author(s)
      Miyauchi Kosuke、Adachi Yu、Tonouchi Keisuke、Yajima Taiki、Harada Yasuyo、Fukuyama Hidehiro、Deno Senka、Iwakura Yoichiro、Yoshimura Akihiko、Hasegawa Hideki、Yugi Katsuyuki、Fujii Shin-ichiro、Ohara Osamu、Takahashi Yoshimasa、Kubo Masato
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41467-021-24090-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-21H02394, KAKENHI-PROJECT-20K07545, KAKENHI-PROJECT-21K08192
  • [Journal Article] IFN-γ and IL-17A regulate intestinal crypt production of CXCL10 in the healthy and inflamed colon2020

    • Author(s)
      Walrath Travis、Malizia Robert A.、Zhu Xinjun、Sharp Stephen P.、D'Souza Shanti S.、Lopez-Soler Reynold、Parr Brian、Kartchner Brittany、Lee Edward C.、Stain Steven C.、Iwakura Yoichiro、O'Connor William
    • Journal Title

      American Journal of Physiology-Gastrointestinal and Liver Physiology

      Volume: 318 Issue: 3 Pages: G479-G489

    • DOI

      10.1152/ajpgi.00208.2019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Psoriasis-like skin disorder in transgenic mice expressing a RIG-I Singleton?Merten syndrome variant2020

    • Author(s)
      Abu Tayeh Ahmed、Funabiki Masahide、Shimizu Shota、Satoh Saya、Sumin Lee、Iwakura Yoichiro、Kato Hiroki、Fujita Takashi
    • Journal Title

      International Immunology

      Volume: 33 Issue: 4 Pages: 211-224

    • DOI

      10.1093/intimm/dxaa071

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176
  • [Journal Article] Interleukin 17A: a Janus-faced regulator of osteoporosis2020

    • Author(s)
      Scheffler J. M.、Grahnemo L.、Engdahl C.、Drevinge C.、Gustafsson K. L.、Corciulo C.、Lawenius L.、Iwakura Y.、Sj?gren K.、Lagerquist M. K.、Carlsten H.、Ohlsson C.、Islander U.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41598-020-62562-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Context-Dependent IL-1 mRNA-Destabilization by TTP Prevents Dysregulation of Immune Homeostasis Under Steady State Conditions2020

    • Author(s)
      Sneezum Lucy、Eislmayr Kevin、Dworak Helene、Sedlyarov Vitaly、Le Heron Anita、Ebner Florian、Fischer Irmgard、Iwakura Yoichiro、Kovarik Pavel
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 1-16

    • DOI

      10.3389/fimmu.2020.01398

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176
  • [Journal Article] C1q/TNF-related protein 3 regulates chondrogenic cell proliferation via adiponectin receptor 2 (progestin and adipoQ receptor 2)2020

    • Author(s)
      MURAYAMA Masanori A.、IWAKURA Yoichiro
    • Journal Title

      Translational and Regulatory Sciences

      Volume: 2 Issue: 1 Pages: 19-23

    • DOI

      10.33611/trs.2_19

    • NAID

      130007814846

    • ISSN
      2434-4974
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K20681, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K14978
  • [Journal Article] Production of IL-17A at innate immune phase leads to decreased Th1 immune response and attenuated host defense against infection with Cryptococcus deneoformans2020

    • Author(s)
      Sato K, Yamamoto H, Nomura T, Kasamatsu J, Miyasaka T, Tanno D, Matsumoto I, Kagesawa T, Miyahara A, Zong T, Oniyama A, Kawamura K, Yokoyama R, Kitai Y, Ishizuka S, Kanno E, Tanno H, Suda H, Morita M, Yamamoto M, Iwakura Y, Ishii K, Kawakami K
    • Journal Title

      The Journal of Immunology

      Volume: 205 Issue: 3 Pages: 686-698

    • DOI

      10.4049/jimmunol.1901238

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07341, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02851, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K17920
  • [Journal Article] TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron‐autonomous manner2020

    • Author(s)
      Koinuma Shingo、Negishi Ryota、Nomura Riko、Sato Kazuki、Kojima Takuya、Segi‐Nishida Eri、Goitsuka Ryo、Iwakura Yoichiro、Wada Naoyuki、Koriyama Yoshiki、Kiryu‐Seo Sumiko、Kiyama Hiroshi、Nakamura Takeshi
    • Journal Title

      Journal of Neurochemistry

      Volume: - Issue: 4 Pages: 1196-1206

    • DOI

      10.1111/jnc.15235

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06880, KAKENHI-PROJECT-20K07090, KAKENHI-PROJECT-20K20320, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02524, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19H03395, KAKENHI-PROJECT-20H03176, KAKENHI-PROJECT-19K11781, KAKENHI-PROJECT-21H04865, KAKENHI-PROJECT-21H02372, KAKENHI-PROJECT-21K19310
  • [Journal Article] Innate Immune Functions of Astrocytes are Dependent Upon Tumor Necrosis Factor-Alpha2020

    • Author(s)
      Rodgers Kyla R.、Lin Yufan、Langan Thomas J.、Iwakura Yoichiro、Chou Richard C.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 1-15

    • DOI

      10.1038/s41598-020-63766-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-20H03176
  • [Journal Article] IL-17A promotes fatty acid uptake through the IL-17A/IL-17RA/p-STAT3/FABP4 axis to fuel ovarian cancer growth in an adipocyte-rich microenvironment2020

    • Author(s)
      Chunyan Yu、 Xiulong Niu、Yongrui Du、Yan Chen、Xiaomei Liu、Lingling Xu、 Yoichiro Iwakura、Xiaoxia Ma、Yan Li、Zhi Yao、 Weimin Deng
    • Journal Title

      Cancer Immunology, Immunotherapy

      Volume: 69 Issue: 1 Pages: 115-126

    • DOI

      10.1007/s00262-019-02445-2

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Dysregulated skin barrier function in Tmem79 mutant mice promotes IL‐17A‐dependent spontaneous skin and lung inflammation2020

    • Author(s)
      Saunders Sean P.、Floudas Achilleas、Moran Tara、Byrne Ciara M.、Rooney Michael D.、Fahy Caoimhe M. R.、Geoghegan Joan A.、Iwakura Yoichiro、Fallon Padraic G.、Schwartz Christian
    • Journal Title

      Allergy

      Volume: 75 Issue: 12 Pages: 3216-3227

    • DOI

      10.1111/all.14488

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04954, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-20H03176
  • [Journal Article] Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis.2019

    • Author(s)
      Sakurai K, Dainichi T, Garcet S, Tsuchiya S, Yamamoto Y, Kitoh A, Honda T, Nomura T, Egawa G, Otsuka A, Nakajima S, Matsumoto R, Nakano Y, Otsuka M, Iwakura Y, Grinberg-Bleyer Y, Ghosh S, Sugimoto Y, Guttman-Yassky E, Krueger JG, Kabashima K.
    • Journal Title

      J Allergy Clin Immunol

      Volume: 144(4) Issue: 4 Pages: 1036-1049

    • DOI

      10.1016/j.jaci.2019.06.019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08748, KAKENHI-PROJECT-19K22503, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05905, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17H03990, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K19655, KAKENHI-PROJECT-15H05790, KAKENHI-PROJECT-18K08295
  • [Journal Article] IL-1β Plays an Important Role in Pressure Overload-Induced Atrial Fibrillation in Mice2019

    • Author(s)
      Matsushita N, Ishida N, Ibi M, Saito M, Takahashi M, Taniguchi S, Iwakura Y, Morino Y, Taira E, Sawa Y, Hirose M
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 42 Issue: 4 Pages: 543-546

    • DOI

      10.1248/bpb.b18-00363

    • NAID

      130007622152

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2019-04-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18K06781, KAKENHI-PROJECT-18K08112, KAKENHI-PROJECT-19K11772, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] arge scale cacium imaging of the cerebellar vermis during sensory stimulus unravels two response’s components that differ in their spatiotemporal properties.2019

    • Author(s)
      Byk, H., Huang, G. J., Iwakura, Y., and Yarom, Y.
    • Journal Title

      Front. Syst. Neurosci.

      Volume: 13 Pages: 18-18

    • DOI

      10.3389/fnsys.2019.00018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.2019

    • Author(s)
      Drummond, R. A., Swamydas, M., Oikonomou, V., Zhai, B., Dambuza, I. M., Schaefer, B. C., Bohrer, A. C., Mayer-Barber, K. D., Lira, S. A., Iwakura, Y., Filler, S. G., Brown, G. D., Hube, B., Naglik, J. R., Hohl, T. M., and Lionakis, M. S.
    • Journal Title

      Nat Immunol.

      Volume: 20 Issue: 5 Pages: 559-570

    • DOI

      10.1038/s41590-019-0377-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Defect of interferon γ leads to impaired wound healing through prolonged neutrophilic inflammatory response and enhanced MMP-2 activation.2019

    • Author(s)
      Kanno E, Tanno H, Masaki A, Sasaki A, Sato N, Goto M, Shisai M, Yamaguchi K, Takagi N, Shoji M, Kitai Y, Sato K, Kasamatsu J, Ishii K, Miyasaka T, Kawakami K, Imai Y, Iwakura Y, Maruyama R, Tachi M, Kawakami K.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 20(22) Issue: 22 Pages: 5657-5657

    • DOI

      10.3390/ijms20225657

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17913, KAKENHI-PROJECT-19K19494, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-19K22649
  • [Journal Article] Uncoupling the senescence-associated secretory phenotype from cell cycle exit via IL-1 inactivation unveils its pro-tumorigenic role.2019

    • Author(s)
      Lau, L., Porciuncula, A., Yu, A., Iwakura, Y., and David, G.
    • Journal Title

      Mol. Cell Biol.

      Volume: 39 Issue: 12 Pages: 18-35

    • DOI

      10.1128/mcb.00586-18

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Spontaneous atopic dermataitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β.2019

    • Author(s)
      Schwartz, C., Moran, T., Saunders, S. P., Kaszlikowska, A., Floudas, A., Bom, J., Nunez, G., Iwakura, Y., O’Neill, L., Irvine, A. D., McKenzie, A. N. J., Ogg, G., Walsh, P. T., Demengeot, J., and Fallon, P. G.
    • Journal Title

      Allergy

      Volume: 74 Issue: 10 Pages: 1920-1933

    • DOI

      10.1111/all.13801

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis.2019

    • Author(s)
      Blanco-Perez, F., Kato, Y., Gonzalez-Menendez, I., Laino, J., Ohbayashi, M., Burggraf, M., Krause, M., Kirberg, J., Iwakura, Y., Martella, M., Quintanilla-Martinez, L., Shibata, N., Vieths, S., Scheurer, S., and Toda, M.
    • Journal Title

      Sci. Rep.

      Volume: 9 Issue: 1 Pages: 9608-9608

    • DOI

      10.1038/s41598-019-45653-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Role of interleukin-17 in a murine community-associated methicillin-resistant Staphylococcus aureus pneumonia model2019

    • Author(s)
      Shibue Yasushi、Kimura Soichiro、Kajiwara Chiaki、Iwakura Yoichiro、Yamaguchi Keizo、Tateda Kazuhiro
    • Journal Title

      Microbes and Infection

      Volume: 21 Issue: 1 Pages: 33-39

    • DOI

      10.1016/j.micinf.2018.06.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Myeloid C-type lectin receptors in skin/mucoepithelial diseases and tumors.2019

    • Author(s)
      Tang, C., Makusheva, Y., Sun, H., Han, W., and Iwakura, Y.
    • Journal Title

      J. Leukoc. Biol.

      Volume: 106 Issue: 4 Pages: 903-917

    • DOI

      10.1002/jlb.2ri0119-031r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Dectin-1 Contributes to Myocardial Ischemia/Reperfusion Injury by Regulating Macrophage Polarization and Neutrophil Infiltration2019

    • Author(s)
      Fan Qin、Tao Rong、Zhang Hang、Xie Hongyang、Lu Lin、Wang Ting、Su Min、Hu Jian、Zhang Qi、Chen Qiujing、Iwakura Yoichiro、Shen Weifeng、Zhang Ruiyan、Yan Xiaoxiang
    • Journal Title

      Circulation

      Volume: 139 Issue: 5 Pages: 663-678

    • DOI

      10.1161/circulationaha.118.036044

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-15H05787
  • [Journal Article] Dectin-2?induced CCL2 production in tissue-resident macrophages ignites cardiac arteritis2019

    • Author(s)
      Miyabe Chie、Miyabe Yoshishige、Bricio-Moreno Laura、Lian Jeffrey、Rahimi Rod A.、Miura Noriko N.、Ohno Naohito、Iwakura Yoichiro、Kawakami Tamihiro、Luster Andrew D.
    • Journal Title

      Journal of Clinical Investigation

      Volume: 129 Issue: 9 Pages: 3610-3624

    • DOI

      10.1172/jci123778

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K17813, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K10259
  • [Journal Article] AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.2019

    • Author(s)
      Hupa, K. J., Stein, K., Schneider, R., Lysson, M., Schneiker, B., Hornung, V., Latz, E., Iwakura, Y., Kalff, J. C., and Wehner, S.
    • Journal Title

      Sci. Rep.

      Volume: 9 Issue: 1 Pages: 10602-10602

    • DOI

      10.1038/s41598-019-46968-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Dectin-2-Mediated Signaling Leads to Delayed Skin Wound Healing through Enhanced Neutrophilic Inflammatory Response and Neutrophil Extracellular Trap Formation.2019

    • Author(s)
      Miura T, Kawakami K, Kanno E, Tanno H, Tada H, Sato N, Masaki A, Yokoyama R, Kawamura K, Kitai Y, Takagi N, Yamaguchi K, Yamaguchi N, Kyo Y, Ishii K, Imai Y, Saijo S, Iwakura Y, Tachi M.
    • Journal Title

      J Invest Dermatol

      Volume: 139(3) Issue: 3 Pages: 702-711

    • DOI

      10.1016/j.jid.2018.10.015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09473, KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K11909, KAKENHI-PROJECT-17K19710, KAKENHI-PROJECT-17K17393, KAKENHI-PROJECT-19K10143, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K11824
  • [Journal Article] Epidermal loss of phospholipase Cδ1 attenuates irritant contact dermatitis2019

    • Author(s)
      Shiratori K, Kanemaru K, Ogura T, Nakajima A, Sugizaki Y, Fukuyama T, Iwakura Y, Nakamura Y, Fukami K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 511 Issue: 2 Pages: 330-335

    • DOI

      10.1016/j.bbrc.2019.02.046

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02575, KAKENHI-PROJECT-19K16080, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17H04051
  • [Journal Article] IL-1R2 deficiency suppresses dextran sodium sulfate-induced colitis in mice via regulation of microbiota.2018

    • Author(s)
      Yoshida, K., Murayama, M., Shimizu, K., Tang, C., Katagiri, N., Matsuo, K., Fukai F., and Iwakura, Y.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 496 Issue: 3 Pages: 934-940

    • DOI

      10.1016/j.bbrc.2018.01.116

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-17K14978
  • [Journal Article] Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing T(reg) cells through modification of the intestinal microbiota.2018

    • Author(s)
      Tang C, Kakuta S, Shimizu K, Kadoki M, Kamiya T, Shimazu T, Kubo S, Saijo S, Ishigame H, Nakae S, Iwakura Y.
    • Journal Title

      Nat Immunol.

      Volume: 19 Issue: 7 Pages: 755-765

    • DOI

      10.1038/s41590-018-0134-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation2018

    • Author(s)
      Zhang Cun-Jin、Jiang Meiling、Zhou Hao、Liu Weiwei、Wang Chenhui、Kang Zizhen、Han Bing、Zhang Quanri、Chen Xing、Xiao Jianxin、Fisher Amanda、Kaiser William J.、Murayama Masanori A.、Iwakura Yoichiro、Gao Ji、Carman Julie、Dongre Ashok、Dubyak George、Abbott Derek W.、Shi Fu-Dong、Ransohoff Richard M.、Li Xiaoxia
    • Journal Title

      Journal of Clinical Investigation

      Volume: 128 Issue: 12 Pages: 5399-5412

    • DOI

      10.1172/jci121901

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K14978
  • [Journal Article] A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis2018

    • Author(s)
      Ueno Keigo、Urai Makoto、Sadamoto Sota、Shinozaki Minoru、Takatsuka Shogo、Abe Masahiro、Otani Yoshiko、Yanagihara Nao、Shimizu Kiminori、Iwakura Yoichiro、Shibuya Kazutoshi、Miyazaki Yoshitsugu、Kinjo Yuki
    • Journal Title

      Mucosal Immunology

      Volume: 12 Issue: 1 Pages: 265-276

    • DOI

      10.1038/s41385-018-0094-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K18385, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16H05349, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K10040
  • [Journal Article] Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusion2018

    • Author(s)
      Marazioti A, Lilis I, Vreka M, Apostolopoulou H, Kalogeropoulou A, Giopanou I, Giotopoulou GA, Krontira AC, Iliopoulou M, Kanellakis NI, Agalioti T, Giannou AD, Jones-Paris C, Iwakura Y, Kardamakis D, Blackwell TS, Taraviras S, Spella M, Stathopoulos GT.
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 672-672

    • DOI

      10.1038/s41467-018-03051-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
  • [Journal Article] NK Cells Control Tumor-Promoting Function of Neutrophils in Mice2018

    • Author(s)
      Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y
    • Journal Title

      Cancer Immunol Res

      Volume: 印刷中 Issue: 3 Pages: 348-357

    • DOI

      10.1158/2326-6066.cir-17-0204

    • NAID

      120006402039

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15K08902, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
  • [Journal Article] MAIT cells protect against pulmonary Legionella longbeachae infection2018

    • Author(s)
      Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z.
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 3350-3350

    • DOI

      10.1038/s41467-018-05202-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671
  • [Journal Article] HER2 overexpression triggers an IL-1α pro-inflammatory circuit to drive tumorigenesis and promote chemotherapy resistance.2018

    • Author(s)
      Liu, S., Lee, J. S., Jie, C., Park, M. H., Iwakura, Y., Patel, Y., Soni, M., Reisman, D., and Chen, H.
    • Journal Title

      Cancer Res.

      Volume: 78 Pages: 2040-2051

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Journal Article] HER2 overexpression triggers an IL-1α pro-inflammatory circuit to drive tumorigenesis and promote chemotherapy resistance.2018

    • Author(s)
      Liu, S., Lee, J. S., Jie, C., Park, M. H., Iwakura, Y., Patel, Y., Soni, M., Reisman, D., and Chen, H.
    • Journal Title

      Cancer Res.

      Volume: - Issue: 8 Pages: 2040-2051

    • DOI

      10.1158/0008-5472.can-17-2761

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045
  • [Journal Article] IL-36α is involved in hapten-specific T-cell induction, but not local inflammation, during contact hypersensitivity2018

    • Author(s)
      Numata Takafumi、Yoshizaki Takamichi、Yamaguchi Sachiko、Shimura Eri、Iwakura Yoichiro、Harada Kazutoshi、Sudo Katsuko、Tsuboi Ryoji、Nakae Susumu
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 506 Issue: 3 Pages: 429-436

    • DOI

      10.1016/j.bbrc.2018.10.104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10256, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02847
  • [Journal Article] Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation.2018

    • Author(s)
      Ikenoue T, Terakado Y, Zhu C, Liu X, Ohsugi T, Matsubara D, Fujii T, Kakuta S,Kubo S, Shibata T, Yamaguchi K, Iwakura Y, Furukawa Y.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 2021-2021

    • DOI

      10.1038/s41598-018-19769-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08672, KAKENHI-PROJECT-16K10558, KAKENHI-PROJECT-17K09369, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-26860227, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PUBLICLY-16H01569, KAKENHI-PROJECT-17K07214
  • [Journal Article] IL-25 enhances Th17 cell-mediated contact dermatitis by promoting IL-1b production by dermal dendritic cells2018

    • Author(s)
      Suto H, Nambu A, Morita H, Yamaguchi S, Numata T, Yoshizaki T, Shimura E, Arae K, Asada Y, Motomura K, Kaneko M, Abe T, Matsuda A, Iwakura Y, Okumura K, Saito H, Matsumoto K, Sudo K, Nakae S
    • Journal Title

      J Allergy Clin Immunol

      Volume: In press Issue: 5 Pages: 1500-1509

    • DOI

      10.1016/j.jaci.2017.12.1007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-16K20333, KAKENHI-PROJECT-18K08395, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] Increased mTOR cancels out the effect of reduced Xbp-1 on antibody secretion in IL-1α-deficient B cells2018

    • Author(s)
      Zhu Gaizhi、Liu Xiaoling、Fang Ying、Zhai Bing、Xu Ruonan、Han Gencheng、Chen Guojiang、Xiao He、Hou Chunmei、Shen Beifen、Li Yan、Iwakura Yoichiro、Wang Liang、Jiang Zhenyu、Ma Ning、Liu Guangchao、Wang Renxi
    • Journal Title

      Cellular Immunology

      Volume: 328 Pages: 9-17

    • DOI

      10.1016/j.cellimm.2018.02.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787
  • [Journal Article] Interleukin-17-producing γδT (γδ17) cells in inflammatory diseases2018

    • Author(s)
      Aoi Akitsu, Yoichiro Iwakura
    • Journal Title

      Immunology

      Volume: 155 Issue: 4 Pages: 418-426

    • DOI

      10.1111/imm.12993

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671
  • [Journal Article] The ATP Transporter VNUT Mediates Induction of Dectin-1-Triggered Candida Nociception.2018

    • Author(s)
      Maruyama K, Takayama Y, Sugisawa E, Yamanoi Y, Yokawa T, Kondo T, Ishibashi KI, Sahoo BR, Takemura N, Mori Y, Kanemaru H, Kumagai Y, Martino MM, Yoshioka Y, Nishijo H, Tanaka H, Sasaki A, Ohno N, Iwakura Y, Moriyama Y, Nomura M, Akira S, Tominaga M.
    • Journal Title

      iScience

      Volume: 6 Pages: 306-318

    • DOI

      10.1016/j.isci.2018.08.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09885, KAKENHI-PROJECT-16K19148, KAKENHI-PROJECT-17K15793, KAKENHI-PLANNED-15H05928, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-16H01849, KAKENHI-PROJECT-18H01841, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02970, KAKENHI-PROJECT-17K15725
  • [Journal Article] Apaf1 plays a negative regulatory role in T cell responses by suppressing activation of antigen-stimulated T cells.2018

    • Author(s)
      Tong, H., Miyake, Y., Mi-Ichi, F., Iwakura, Y., Hara, H. and Yoshida, H.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 3 Pages: 0195119-0195119

    • DOI

      10.1371/journal.pone.0195119

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08888, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K08842, KAKENHI-PROJECT-16K19117, KAKENHI-PUBLICLY-16H01365, KAKENHI-PUBLICLY-18H04675, KAKENHI-PROJECT-18K07087
  • [Journal Article] A model of TH17-associated ileal hyperplasia that requires both IL-17A and IFNγ to generate self-tolerance and prevent colitis2018

    • Author(s)
      Jeschke Jonathan C.、Mayne Christopher G.、Ziegelbauer Jennifer、DeCiantis Christopher L.、Singh Selina、Kumar Suresh N.、Suchi Mariko、Iwakura Yoichiro、Drobyski William R.、Salzman Nita H、Williams Calvin B.
    • Journal Title

      Mucosal Immunology

      Volume: 11 Issue: 4 Pages: 1127-1137

    • DOI

      10.1038/s41385-018-0023-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671
  • [Journal Article] IL-36α from Skin-Resident Cells Plays an Important Role in the Pathogenesis of Imiquimod-Induced Psoriasiform Dermatitis by Forming a Local Autoamplification Loop.2018

    • Author(s)
      Hashiguchi Y, Yabe R, Chung SH, Murayama MA, Yoshida K, Matsuo K, Kubo S, Saijo S, Nakamura Y, Matsue H, Iwakura Y.
    • Journal Title

      J Immunol.

      Volume: 201 Issue: 1 Pages: 167-182

    • DOI

      10.4049/jimmunol.1701157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19437, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-17K14978
  • [Journal Article] IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse.2018

    • Author(s)
      Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, Nakamura S, Kaneko Y, Kobayashi S, Harato K, Yoshimura A, Iwakura Y, Takeuchi T, Matsumoto M, Nakamura M, Niki Y, Miyamoto T.
    • Journal Title

      Sci Rep.

      Volume: - Issue: 1 Pages: 15783-15783

    • DOI

      10.1038/s41598-018-34173-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15198, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-16K10917
  • [Journal Article] Inhibition of interleukin-1 suppresses angiotensin II-induced aortic inflammation and aneurysm formation.2018

    • Author(s)
      Isoda K, Akita K, Kitamura K, Sato-Okabayashi Y, Kadoguchi T, Isobe S, Ohtomo F, Sano M, Shimada K, Iwakura Y, Daida H
    • Journal Title

      Int J Cardiol

      Volume: 270 Pages: 221-227

    • DOI

      10.1016/j.ijcard.2018.05.072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K17935, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K09522, KAKENHI-PROJECT-16K16607
  • [Journal Article] Production of low-molecular weight soluble yeast β-glucan by an acid degradation method2018

    • Author(s)
      Ishimoto Yuina、Ishibashi Ken-ichi、Yamanaka Daisuke、Adachi Yoshiyuki、Kanzaki Ken、Iwakura Yoichiro、Ohno Naohito
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 107 Pages: 2269-2278

    • DOI

      10.1016/j.ijbiomac.2017.10.094

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-15H05787
  • [Journal Article] Host defense against oral microbiota by bone-damaging T cells2018

    • Author(s)
      Tsukasaki Masayuki、Komatsu Noriko、Nagashima Kazuki、Nitta Takeshi、Pluemsakunthai Warunee、Shukunami Chisa、Iwakura Yoichiro、Nakashima Tomoki、Okamoto Kazuo、Takayanagi Hiroshi
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 701-701

    • DOI

      10.1038/s41467-018-03147-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19582, KAKENHI-PROJECT-16H05202, KAKENHI-PROJECT-16H05506, KAKENHI-PROJECT-15H05653, KAKENHI-PROJECT-15F15414, KAKENHI-PROJECT-15J05324, KAKENHI-PROJECT-15H05703, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-16K15252, KAKENHI-PROJECT-26713015
  • [Journal Article] BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance2018

    • Author(s)
      Matsushita Takashi、Kobayashi Tadahiro、Mizumaki Kie、Kano Miyu、Sawada Tomoyo、Tennichi Momoko、Okamura Ai、Hamaguchi Yasuhito、Iwakura Yoichiro、Hasegawa Minoru、Fujimoto Manabu、Takehara Kazuhiko
    • Journal Title

      Science Advances

      Volume: 4 Issue: 7 Pages: 9944-9944

    • DOI

      10.1126/sciadv.aas9944

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05045, KAKENHI-PROJECT-18H02671, KAKENHI-PROJECT-16K10147
  • [Journal Article] Dectin-2 deficiency modulates Th1 differentiation and improves wound healing after myocardial infarction.2017

    • Author(s)
      Yan, X., Zhang, H., Fan, Q., Hu, J., Tao, R., Chen, Q., Iwakura, Y., Shen, W., Lu, L., Zhang, Q., and Zhang, R.
    • Journal Title

      Circ. Res.

      Volume: 120 Issue: 7 Pages: 1116-1129

    • DOI

      10.1161/circresaha.116.310260

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Nociceptors Boost the Resolution of Fungal Osteoinflammation via the TRP Channel-CGRP-Jdp2 Axis2017

    • Author(s)
      Maruyama Kenta、Takayama Yasunori、Kondo Takeshi、Ishibashi Ken-ichi、Sahoo Bikash Ranjan、Kanemaru Hisashi、Kumagai Yutaro、Martino Mika?l M.、Tanaka Hiroki、Ohno Naohito、Iwakura Yoichiro、Takemura Naoki、Tominaga Makoto、Akira Shizuo
    • Journal Title

      Cell Reports

      Volume: 19 Issue: 13 Pages: 2730-2742

    • DOI

      10.1016/j.celrep.2017.06.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15725, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15H02501, KAKENHI-PROJECT-15H05686, KAKENHI-PROJECT-16K15665, KAKENHI-PROJECT-16K19148
  • [Journal Article] Interleukin-17A-deficient mice are highly susceptible to Toxoplasma gondii infection due to excessively induced T. gondii HSP70 and interferon gamma production2017

    • Author(s)
      Moroda M, Takamoto M, Iwakura Y, Nakayama J, Aosai F
    • Journal Title

      Infection and Immunity

      Volume: 85 Issue: 12 Pages: 00399-17

    • DOI

      10.1128/iai.00399-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15255, KAKENHI-PROJECT-15H05787
  • [Journal Article] Modulation of an innate immune response by soluble yeast β-glucan prepared by a heat degradation method.2017

    • Author(s)
      Ishimoto, Y., Ishibashi, K. I., Yamanaka, D., Adachi, Y., Kanzaki, K., Okita, K., Iwakura, Y., and Ohno, N.
    • Journal Title

      Int. J. Biol. Macromol.

      Volume: 104 Pages: 367-376

    • DOI

      10.1016/j.ijbiomac.2017.06.036

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Preferentially expanding Vγ1+ γδ T cells are associated with protective immunity against Plasmodium infection in mice.2017

    • Author(s)
      Inoue SI, Niikura M, Asahi H, Iwakura Y, Kawakami Y, Kobayashi F.
    • Journal Title

      Eur J Immunol.

      Volume: 47 Issue: 4 Pages: 685-691

    • DOI

      10.1002/eji.201646699

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15K08449, KAKENHI-PROJECT-15K08451, KAKENHI-PROJECT-15K19085
  • [Journal Article] Dectin-1 Plays an Important Role in House Dust Mite-Induced Allergic Airway Inflammation through the Activation of CD11b+ Dendritic Cells.2017

    • Author(s)
      Ito T, Hirose K, Norimoto A, Tamachi T, Yokota M, Saku A, Takatori H, Saijo S, Iwakura Y, Nakajima H.
    • Journal Title

      J Immunol.

      Volume: 198 Issue: 1 Pages: 61-70

    • DOI

      10.4049/jimmunol.1502393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26461184, KAKENHI-PROJECT-16K09573, KAKENHI-PROJECT-16K15271
  • [Journal Article] Absence of DCIR1 reduces the rate of endotoxemic hepatitis in mice.2017

    • Author(s)
      Ishiguro T, Fukawa T, Akaki K, Nagaoka K, Takeda T, Iwakura Y ,Inaba K, Takahara K.
    • Journal Title

      Eur J Immunol.

      Volume: 47 Issue: 4 Pages: 704-712

    • DOI

      10.1002/eji.201646814

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K08737
  • [Journal Article] IL-17A contributes to reducing IFN-gamma/IL-4 ratio and persistence of Entamoeba histolytica during intestinal amebiasis2017

    • Author(s)
      Deloer, S. Nakamura, R. Kikuchi, M. Moriyasu, T. Kalenda, Y. D. J. Mohammed, E. S. Senba, M. Iwakura, Y. Yoshida, H. Hamano, S.
    • Journal Title

      Parasitol Int

      Volume: 66 Issue: 6 Pages: 817-823

    • DOI

      10.1016/j.parint.2017.09.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08842, KAKENHI-PROJECT-26305013, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17H04649, KAKENHI-PROJECT-16K19118
  • [Journal Article] Production of low-molecular weight soluble yeast β-glucans by an acid degradation method.2017

    • Author(s)
      Ishimoto, Y., Ishibashi, K. I., Yamanaka, D., Adachi, Y., Kanzaki, K., Iwakura, Y., and Ohno, N.
    • Journal Title

      Int. J. Biol. Macromol.

      Volume: 107 Issue: 3 Pages: 2269-2278

    • DOI

      10.1038/mi.2017.86

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-18H02671
  • [Journal Article] IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin.2017

    • Author(s)
      Takagi N, Kawakami K, Kanno E, Tanno H, Takeda A, Ishii K, Imai Y, Iwakura Y, Tachi M.
    • Journal Title

      Dermatol.

      Volume: 26 Issue: 2 Pages: 137-144

    • DOI

      10.1111/exd.13115

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15H06052, KAKENHI-PROJECT-26462723
  • [Journal Article] Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells.2017

    • Author(s)
      Ishida T, Suzuki S, Lai CY, Yamazaki S, Kakuta S, Iwakura Y, Nojima M, Takeuchi Y, Higashihara M, Nakauchi H, Otsu M.
    • Journal Title

      Stem Cells.

      Volume: 35 Issue: 4 Pages: 989-1002

    • DOI

      10.1002/stem.2524

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H02661, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-15K20949
  • [Journal Article] Neutralization of either IL-17A or IL-17F is sufficient to inhibit house dust mite induced allergic asthma in mice.2017

    • Author(s)
      Chenuet, P., Fauconnier, L., Madouri. F., Marchiol, T., Rouxel, N., Ledru, A., Mauny, P., Lory, R., Uttenhove, C., van Snick. J., Iwakura, Y., di Padova, F., Quesniaux, V., Togbe, D., and Ryffel, B.
    • Journal Title

      Clin. Sci. (Lond)

      Volume: 131 Issue: 20 Pages: 2533-2548

    • DOI

      10.1042/cs20171034

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Brain Interleukin-1 Facilitates Learning of a Water Maze Spatial Memory Task in Young Mice.2017

    • Author(s)
      Takemiya T, Fumizawa K, Yamagata K, Iwakura Y, Kawakami M.
    • Journal Title

      Front Behav Neurosci.

      Volume: 11 Pages: 202-202

    • DOI

      10.3389/fnbeh.2017.00202

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10064, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-15H05787
  • [Journal Article] Phospholipase Cδ1 regulates p38 MAPK activity and skin barrier integrity.2017

    • Author(s)
      Kaori Kanemaru, Yoshikazu Nakamura, Kengo Totoki, Takatsugu Fukuyama, Madoka Shoji, Hisae Kaneko, Kanako Shiratori, Atsuko Yoneda, Takafumi Inoue, Yoichiro Iwakura, Kenji Kabashima, Kiyoko Fukami
    • Journal Title

      Cell Death & Differentiation

      Volume: in press Issue: 6 Pages: 1079-1090

    • DOI

      10.1038/cdd.2017.56

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293071, KAKENHI-PROJECT-26440036, KAKENHI-PROJECT-15K15417, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-17H04051
  • [Journal Article] Fungal-derived cues promote ocular autoimmunity through a Dectin-2/Card9-mediated mechanism.2017

    • Author(s)
      Brown, B. R., Lee, E. J., Snow, P. E., Vance, E. E., Iwakura, Y., Ohno, N., Miura, N., Lin, X., Brown, G. D., Wells, C. A., Smith, J. R., Caspi, R. R., and Rosenzweig, H. L.
    • Journal Title

      Clin. Exp. Immunol.

      Volume: 190 Issue: 3 Pages: 293-303

    • DOI

      10.1111/cei.13021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation2017

    • Author(s)
      Furukawa, K. Fuse, I. Iwakura, Y. Sotoyama, H. Hanyu, O. Nawa, H. Sone, H. Takei, N.
    • Journal Title

      Cardiovascular diabetology

      Volume: 16 Issue: 1 Pages: 20-20

    • DOI

      10.1186/s12933-017-0505-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26350885, KAKENHI-PROJECT-16K07053, KAKENHI-PROJECT-15H05787
  • [Journal Article] IL-17A promotes neutrophilic inflammation and disturbs acute wound healing in skin.2017

    • Author(s)
      Takagi N, Kawakami K, Kanno E, Tanno H, Takeda A, Ishii K, Imai Y, Iwakura Y, Tachi M
    • Journal Title

      Dermatol.

      Volume: 26 Pages: 137-144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis2017

    • Author(s)
      Morita M, Iwasaki R, Sato Y, Kobayashi T, Watanabe R, Oike T, Nakamura S, Keneko Y, Miyamoto K, Ishihara K, Iwakura Y, Ishii K, Matsumoto M, Nakamura M, Kawana H, Nakagawa T, Miyamoto T.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 46322-46322

    • DOI

      10.1038/srep46322

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10490, KAKENHI-PROJECT-16K10917, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-15H04963, KAKENHI-PROJECT-15K11023
  • [Journal Article] Megakaryocytes compensate for Kit insufficiency in murine arthritis.2017

    • Author(s)
      Cunin, P., Penke, L. R., Thon, J. N., Monach, P. A., Jones, T., Chang, M. H., Chen, M. M., Melki, I., Lacroix, S., Iwakura, Y., Ware, J., Gurish, M. F., Italiano, J. E., Boilard, E., and Nigrovic, P. A.
    • Journal Title

      J. Clin. Invest.

      Volume: 27 Issue: 5 Pages: 1714-1724

    • DOI

      10.1172/jci84598

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation.2017

    • Author(s)
      Wang, J., Ge, P., Qiang, L., Tian, F., Zhao, D., Chai, Q., Zhu, M., Zhou, R., Meng, G., Iwakura, Y., Gao, G. F., and Liu, C. H.
    • Journal Title

      Nat. Commun.

      Volume: 8 Issue: 8 Pages: 244-244

    • DOI

      10.4049/jimmunol.1700655

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.2017

    • Author(s)
      Nakamura F, Okada T, Shishikura M, Uetani N, Taniguchi M, Yagi T, Iwakura Y, Ohshima T, Goshima Y, Strittmatter SM.
    • Journal Title

      J Neurosci

      Volume: 37 Issue: 30 Pages: 7125-7139

    • DOI

      10.1523/jneurosci.2519-16.2017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07062, KAKENHI-PROJECT-16K08447, KAKENHI-PROJECT-15H05787
  • [Journal Article] Macrophage-derived IL-1α promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity.2017

    • Author(s)
      Zhang, C., Feng, J., Du, J., Zhuo, Z., Yang, S., Zhang, W., Wang, W., Zhang, S., Iwakura, Y., Meng, G., Fu, Y. X., Hou, B., and Tang, H.
    • Journal Title

      Cell. Mol. Immunol.

      Volume: - Issue: 11 Pages: 973-982

    • DOI

      10.1038/cmi.2017.22

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] LC3-associated phagocytosis is required for dendritic cell inflammatory cytokine response to gut commensal yeast Saccharomyces cerevisiae.2017

    • Author(s)
      Lamprinaki, D., Beasy, G., Zhekova, A., Wittmann, A., James, S., Dicks, J., Iwakura, Y., Saijo, S., Wang, X., Chow, C. W., Roberts, I., Korcsmaros, T., Mayer, U., Wileman, T., and Kawasaki, N.
    • Journal Title

      Front. Immunol.

      Volume: 8 Pages: 1397-1397

    • DOI

      10.3389/fimmu.2017.01397

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-16K15271
  • [Journal Article] An ocular commensal protects from corneal infection by driving an IL-17 response from mucosal γδT cells.2017

    • Author(s)
      St Leger, A. J., Desal, J. V., Drummond, R. A., Kugadas, A., Almaghrabi, F., Silver, P., Raychaudhuri, K., Gadjeva, M., Iwakura, Y., Lionakis, M., and Caspi, R. R.
    • Journal Title

      Immunity

      Volume: 47 Issue: 1 Pages: 148-158

    • DOI

      10.1016/j.immuni.2017.06.014

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] Bone marrow transplantation alters lung antigen-presenting cells to promote Th17 reponse and the development of pneumonitis and fibrosis following gammaherpesvirus infection.2016

    • Author(s)
      Zhou, X., Loomis-King, H., Gurczynski, S. J., Wilke, C. A., Konopka, K. E., Ptaschinski, C., Coomes, S. M., Iwakura, Y., van Dyk, L. F., Lukacs, N. W., and Moore, B. B.
    • Journal Title

      Mucosal Immunol.

      Volume: 9 Issue: 3 Pages: 610-620

    • DOI

      10.1038/mi.2015.85

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] T cell-intrinsic ASC critically prootes Th17-mediated experimental autoimmune encephalomyelitis.2016

    • Author(s)
      Martin, B. N. , et al.
    • Journal Title

      Nat. Immunol.

      Volume: 17 Issue: 5 Pages: 583-592

    • DOI

      10.1038/ni.3389

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Adiponectin enhances antibacterial activity of hematopoietic cells by suppressing bone marrow inflammation.2016

    • Author(s)
      Masamoto Y, Arai S, Sato T, Yoshimi A, Kubota N, Takamoto I, Iwakura Y, Yoshimura A, Kadowaki T, Kurokawa M
    • Journal Title

      Immunity

      Volume: 44 Issue: 6 Pages: 1422-33

    • DOI

      10.1016/j.immuni.2016.05.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01481, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25221305, KAKENHI-PROJECT-16K15500, KAKENHI-PROJECT-26000012
  • [Journal Article] Isolation of joint-infiltrating cells.2016

    • Author(s)
      Akitsu A, Iwakura Y.
    • Journal Title

      Bio-Protocol.

      Volume: 6 Issue: 17

    • DOI

      10.21769/bioprotoc.1911

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Cross reactivity of S. aureus to murine cytokine assays: A source of discrepancy.2016

    • Author(s)
      Javed, N., Xue, G., Lu, A., Xing, Y., Iwakura, Y., Xiao, H., Lecoeur, H., Spath, G. F., and Meng, G.
    • Journal Title

      Cytokine

      Volume: 81 Pages: 101-108

    • DOI

      10.1016/j.cyto.2016.03.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Involvement of IL-17A-producing TCR γδ T cells in late protective immunity against pulmonary Mycobacterium tuberculosis infection.2016

    • Author(s)
      Umemura M, Okamoto-Yoshida Y, Yahagi A, Touyama S, Nakae S, Iwakura Y, Matsuzaki G.
    • Journal Title

      Immun Inflamm Dis.

      Volume: 4 Issue: 4 Pages: 401-412

    • DOI

      10.1002/iid3.121

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15K08468
  • [Journal Article] Expression of receptor protein tyrosine phosphatase δ, PTPδ, in mouse central nervous system.2016

    • Author(s)
      Shishikura, M., Nakamura, F., Yamashita, N., Uetani, N., Iwakura, Y., and Goshima, Y.
    • Journal Title

      Brain Res.

      Volume: 1642 Pages: 244-254

    • DOI

      10.1016/j.brainres.2016.03.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K07062
  • [Journal Article] Dectin-2-dependent host defense in mice infected with serotype 3 Streptococcus pneumoniae2016

    • Author(s)
      Akahori Y, Miyasaka T, Toyama M, Matsumoto I, Miyahara A, Zong T, Ishii K, Kinjo Y, Miyazaki Y, Saijo S, Iwakura Y, Kawakami K.
    • Journal Title

      BMC Immunol

      Volume: 17 Issue: 1 Pages: 1-1

    • DOI

      10.1186/s12865-015-0139-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25713038, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
  • [Journal Article] Interleukin-17A promotes aortic endothelial cell activation via transcriptionally and post-transcriptionally activating p38 MAPK pathway.2016

    • Author(s)
      Mai, J., Nanayakkara, G., Lopez-Pastrana, J., Li, X., Li, Y. F., Wang, X., Song, A., Virtue, A., Shao, Y., Shan, H., Liu, F., Autieri, M. V., Kunapuli, S. P., Iwakura, Y., Jiang, X., Wang, H., Yang, X. F.
    • Journal Title

      J. Biol. Chem.

      Volume: 291 Issue: 10 Pages: 4939-4954

    • DOI

      10.1074/jbc.m115.690081

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] IL-17-producing γδ T cells enhance bone regeneration2016

    • Author(s)
      Ono T, et al.
    • Journal Title

      Nat Commun

      Volume: 7 Issue: 1 Pages: 10928-10928

    • DOI

      10.1038/ncomms10928

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-15H05653, KAKENHI-PROJECT-14J03013, KAKENHI-PROJECT-25460606, KAKENHI-PROJECT-25670773, KAKENHI-PROJECT-15H05703, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H05506
  • [Journal Article] IL-21 inhibits IL-17A-producing γδ T cell response after infection with Bacillus Calmette-Guerin via induction of apoptosis2016

    • Author(s)
      Huang Y., Matsumura Y., Hatano, S., Noguchi N., Murakamia, T., Iwakura Y., Sun X., Oharad N., Yoshikai Y.
    • Journal Title

      Innate Immun.

      Volume: 22 Issue: 8 Pages: 588-597

    • DOI

      10.1177/1753425916664125

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293098
  • [Journal Article] Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells.2016

    • Author(s)
      Wittmann A, Lamprinaki D, Bowles KM, Katzenellenbogen E, Knirel YA, Whitfield C, Nishimura T, Matsumoto N, Yamamoto K, Iwakura Y, Saijo S, Kawasaki N.
    • Journal Title

      J Biol Chem.

      Volume: 291 Issue: 34 Pages: 17629-38

    • DOI

      10.1074/jbc.m116.741256

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
  • [Journal Article] Immune complexes indirectly suppress the generation of Th17 responses in vivo.2016

    • Author(s)
      Ciraci, C., Janczy, J. R., Jain, N., Haasken, S., Pecli, E. Silva, C., Benjamim, C. F., Sadler, J. J., Olivier. A. K., Iwakura, Y., Shayakhmetov, D. M., Sutterwala, F. S., and Cassel, S. L.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 3 Pages: e0151252-e0151252

    • DOI

      10.1371/journal.pone.0151252

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis.2016

    • Author(s)
      Kimura Y., Inoue A.., Hangai S.., Saijo S., Negishi H., Nishio J., Yamasaki S., Iwakura Y., Yanai H., Taniguchi T.
    • Journal Title

      Proc. Natl. Acad. Sci. U S A.

      Volume: 113 Issue: 49 Pages: 14097-14102

    • DOI

      10.1073/pnas.1617903113

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16H06747, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
  • [Journal Article] IL-17A-producing CD30(+) Vδ1 T cells drive inflammation-induced cancer progression.2016

    • Author(s)
      Kimura Y, Nagai N, Tsunekawa N, Sato-Matsushita M, Yoshimoto T, Cua DJ, Iwakura Y, Yagita H, Okada F, Tahara H, Saiki I, Irimura T, Hayakawa Y.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 9 Pages: 1206-14

    • DOI

      10.1111/cas.13005

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15J11569, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-26290059, KAKENHI-PROJECT-26430158, KAKENHI-PROJECT-26460472, KAKENHI-PROJECT-15K07947, KAKENHI-PROJECT-15K08433, KAKENHI-PROJECT-15K08902, KAKENHI-PROJECT-26670023
  • [Journal Article] Phosphoinositide 3-Kinase δ Regulates Dectin-2 Signaling and the Generation of Th2 and Th17 Immunity.2016

    • Author(s)
      Lee MJ, Yoshimoto E, Saijo S, Iwakura Y, Lin X, Katz HR, Kanaoka Y, Barrett NA.
    • Journal Title

      J Immunol.

      Volume: 197 Issue: 1 Pages: 278-87

    • DOI

      10.4049/jimmunol.1502485

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-16K15271
  • [Journal Article] Expression of Concern. Low Concentration of Interleukin-1β Induces FLICE-Inhibitory Protein-Mediated β-Cell Proliferation in Human Pancreatic Islets.2016

    • Author(s)
      Maedler K, Schumann DM, Sauter N, Ellingsgaard H, Bosco D, Baertschiger R, Iwakura Y, Oberholzer J, Wollheim CB, Gauthier BR, Donath MY.
    • Journal Title

      Diabetes.

      Volume: 65 Issue: 8 Pages: 2462-2462

    • DOI

      10.2337/db16-ec08a

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] IL-1 receptor antagonist inhibits pancreatic cancer growth by abrogating NF-κB activation.2016

    • Author(s)
      Zhuang, Z. N., Ju, H. Q., Aguilar, M., Gocho, T., Li, H., Iida, T., Lee, H., Fan, X., Zhou, H., Ling, J., Li, Z., Fu, J., Wu, M., Li, M., Melisi, D., Iwakura, Y., Xu, K., Fleming, J. B., and Chiao, P. J.
    • Journal Title

      Clin. Cancer Res.

      Volume: 22 Issue: 6 Pages: 1432-1444

    • DOI

      10.1158/1078-0432.ccr-14-3382

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Two types of IL-17A-producing γδ T cells in protection against pulmonary infection with Klebsiella pneumoniae2016

    • Author(s)
      Murakami T., Hatano S., Yamada H., Iwakura Y., Yoshikai Y.
    • Journal Title

      J. Infect.Dis.

      Volume: 214 Issue: 11 Pages: 1752-1761

    • DOI

      10.1093/infdis/jiw443

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293098
  • [Journal Article] Regulation of inflammation by IL-1A and IL-17F modulates non-alcholic fatty liver disease pathogenesis.2016

    • Author(s)
      Giles, D. A., Moreno-Fernandez, M. E., Stankiewicz, T. E., Cappelletti, M., Huppert, S. S., Iwakura, Y., Dong, C., Shanmukhappa, S. K., and Divanovic, S.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 2 Pages: e0149783-e0149783

    • DOI

      10.1371/journal.pone.0149783

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Interleukin-17A Regulates Renal Sodium Transporters and Renal Injury in Angiotensin II-Induced Hypertension.2016

    • Author(s)
      Norlander AE, Saleh MA, Kamat NV, Ko B, Gnecco J, Zhu L, Dale BL, Iwakura Y, Hoover RS, McDonough AA, Madhur MS.
    • Journal Title

      Hypertension

      Volume: 68 Issue: 1 Pages: 167-74

    • DOI

      10.1161/hypertensionaha.116.07493

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Fine Particles Induce Alveolar Macrophage Death and Interleukin-1α Release to Promote Inducible Bronchus-Associated Lymphoid Tissue Formation.2016

    • Author(s)
      Kuroda E, Ozasa K, Temizoz B, Ohata K, Koo CX, Kanuma T, Kusakabe T, Kobari S, Horie M, Morimoto Y, Nakajima S, Kabashima K, Ziegler SF, Iwakura Y, Ise W, Kurosaki T, Nagatake T, Kunisawa J, Takemura N, Uematsu S, Hayashi M, Aoshi T, Kobiyama K, Coban C, Ishii KJ.
    • Journal Title

      Immunity.

      Volume: 45(6) Issue: 6 Pages: 1299-1310

    • DOI

      10.1016/j.immuni.2016.11.010

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01367, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16H05256, KAKENHI-PROJECT-15K14404, KAKENHI-PROJECT-15K19142, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-15H05790, KAKENHI-PROJECT-16K19148
  • [Journal Article] IL-17A exacerbates cisplatin-based resistance of OVCA via upregulating the expression of ABCG2 and MDR1 through Gli1-mediated Hh signaling.2016

    • Author(s)
      Niu X, Liu W, Wang Y, Liu X, Zhang H, Li Z, Li H, Iwakura Y, Deng W.
    • Journal Title

      Oncotarget

      Volume: 印刷中 Issue: 0

    • DOI

      10.18632/oncotarget.10655

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Mincle activation and the Syk/Card9 signaling axis are cetral to the development of autoimmune disease of the eye.2016

    • Author(s)
      Lee, E. J., Brown, B. R., Vance, E. E., Snow, P. E., Silver, P. B., Heinrichs, D., Lin, X., Iwakura, Y., Wells, C. A., Caspi, R. R., and Rosenzweig, H. L.
    • Journal Title

      J. Immunol.

      Volume: 196 Issue: 7 Pages: 3148-3158

    • DOI

      10.4049/jimmunol.1502355

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Mesenteric lymph nodes contribute to proinflammatory Th17-cell generation during inflammation of the samall intestine in mice.2016

    • Author(s)
      Kawabe, T., Suzuki, N., Yamaki, S., Sun, S. L., Asao, A., Okuyama, Y., So, T., Iwakura, Y., and Ishii, N.
    • Journal Title

      Eur. J. Immunol.

      Volume: 46 Issue: 5 Pages: 1119-1131

    • DOI

      10.1002/eji.201545907

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-15H04640, KAKENHI-PROJECT-15H04742
  • [Journal Article] Dectin-1 and Dectin-2 promote control of the fungal pathogen Trichophyton rubrum independently of IL-17 and adaptive immunity in experimental deep dermatophytosis2016

    • Author(s)
      Fabio Yoshikawa, Rikio Yabe, Yoichiro Iwakura, Sandro Rogerio de Almeida, Shinobu Saijo
    • Journal Title

      Innate Immunity

      Volume: in press Issue: 5 Pages: 316-24

    • DOI

      10.1177/1753425916645392

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-16K15271, KAKENHI-PROJECT-16K19147
  • [Journal Article] IL-1R Type 2 Suppresses Collagen-Induced Arthritis Inhibiting IL-1 Signal on Macrophages.2015

    • Author(s)
      Shimizu K, Nakajima A, Sudo K, Yang L, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, and Iwakura Y.
    • Journal Title

      J Immunol.

      Volume: 194(7) Pages: 3156-68

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Dendritic cell immunoreceptor 1 alters neutrophil responses in the development of experimental colitis.2015

    • Author(s)
      Tokieda, S., Komori, M., Ishiguro, Iwakura, Y., Takahara, K.* and Inaba, K.
    • Journal Title

      BMC Immunol.

      Volume: 16 Issue: 1 Pages: 64-64

    • DOI

      10.1186/s12865-015-0129-5

    • NAID

      120005689211

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25460494, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization.2015

    • Author(s)
      Jee, J., Bonnegarde-Bernard, A., Duverger, A., Iwakura, Y., Cormet-Boyaka, E., Martin, T. L., Steiner, H. E., Bachman, R. C., and Boyaka, P. N.
    • Journal Title

      Mucosal Immunol.

      Volume: 8 Issue: 4 Pages: 735-745

    • DOI

      10.1038/mi.2014.105

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Journal Article] A cruciall role of RORγt in the development of spontaneous sialadenitis-like Sjogren’s syndrome.2015

    • Author(s)
      Iizuka, M., Tsuboi, H., Matsuo, N., Asashima, H., Hirota, T., Kondo, Y., Iwakura, Y., Takahashi, S., Matsumoto, I., Sumida, T.
    • Journal Title

      J. Immunol.

      Volume: 194(1) Pages: 56-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] DCIR in the “osteo-immune” system.2015

    • Author(s)
      1.Maruhashi T, Kaifu T, and Iwakura Y
    • Journal Title

      Oncotarget

      Volume: 6 Issue: 33 Pages: 34051-2

    • DOI

      10.18632/oncotarget.6043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Journal Article] Neutrophils negatively regulate induction of mucosal IgA responses after sublingual immunization.2015

    • Author(s)
      Jee, J., Bonnegarde-Bernard, A., Duverger, A., Iwakura, Y., Cormet-Boyaka, E., Martin, T. L., Steiner, H. E., Bachman, R. C., and Boyaka, P. N.
    • Journal Title

      Mucosal Immunol.,

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Filaggrin deficiency promotes the dissemination of cutaneously inoculated vaccinia virus.2015

    • Author(s)
      Oyoshi, M. K., Beaupre;, J., Venturelli, N., Lewis, C. N., Iwakura, Y., Geha, R. S.
    • Journal Title

      J. Allergy Clin. Immunol.,

      Volume: 未定

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells.2015

    • Author(s)
      Akitsu A, Ishigame H, Kakuta S, Chung SH, Ikeda S, Shimizu K, Kubo S, Liu Y, Umemura M, Matsuzaki G, Yoshikai Y, Saijo S, Iwakura Y.
    • Journal Title

      Nat Commun

      Volume: 6 Issue: 1 Pages: 7464-7464

    • DOI

      10.1038/ncomms8464

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08468, KAKENHI-PROJECT-25293105, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense.2015

    • Author(s)
      Cai, S., Batra, S., Langohr, I., Iwakura, Y., and Jeyaseelan, S.
    • Journal Title

      Mucosal Immunol.

      Volume: 9 Issue: 3 Pages: 718-729

    • DOI

      10.1038/mi.2015.95

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Local IL-17 production exerts a protective role in murine experimental glomerulonephritis.2015

    • Author(s)
      Hamour, S., Gan, P. Y., Pepper, R., Florez Barros, F., Wang, H. H., O'Sullivan, K., Iwakura, Y., Cook, T., Pusey, C., Holdsworth, S., and Salama, A.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 8 Pages: e0136238-e0136238

    • DOI

      10.1371/journal.pone.0136238

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] 1.Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus- mediated regulatory T cell expansion in the intestine.2015

    • Author(s)
      Ce Tang, Tomonori Kamiya, Yang Liu, Motohiko Kadoki, Shigeru Kakuta, Kenshiro Oshima, Masahira Hattori, Kozue Takeshita, Takanori Kanai, Shinobu Saijo and Yoichiro Iwakura
    • Journal Title

      Cell Host & Microbe

      Volume: 18 Issue: 2 Pages: 183-197

    • DOI

      10.1016/j.chom.2015.07.003

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26830058, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015

    • Author(s)
      Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and *Iwakura, Y.
    • Journal Title

      Exp. Anim.

      Volume: 未定

    • NAID

      130005069862

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015

    • Author(s)
      Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.:
    • Journal Title

      Blood

      Volume: 125 Issue: 19 Pages: 3014-23

    • DOI

      10.1182/blood-2014-12-615781

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22130002, KAKENHI-PROJECT-25253069, KAKENHI-PROJECT-26461438, KAKENHI-PROJECT-15K15365, KAKENHI-PROJECT-25461424, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.2015

    • Author(s)
      Seno, A., Maruhashi, T., Kaifu, T., Yabe, R., Fujikado, N., Ma, G., Ikarashi, T., Kakuta, S., and Iwakura, Y.
    • Journal Title

      Exp. Anim.

      Volume: 64 Pages: 109-119

    • NAID

      130005069862

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Antibiotic-killed Staphyococcus aureus induces detructive arthritis in mice.2015

    • Author(s)
      Ali, A., Zhu, X., Kwiecinski, J., Gjertsson, I., Lindholm, C., Iwakura, Y., Wang, X., Lycke, N., Josefsson, E., Pullerits, R., and Jin, T.
    • Journal Title

      Arthritis Rheumatol.

      Volume: 67(1) Pages: 107-116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis.2015

    • Author(s)
      Murayama A.M, Kakuta S, Inoue A, Umeda N, Yonezawa T, Maruhashi T, Tateishi K, Ishigame H, Yabe R, Ikeda S, Seno A, Chi H-H, Hashiguchi Y, Kurata R, Tada T, Kubo S, Sato N, Liu Y, Hattori M, Saijo S, Matsushita M, Fujita T, Sumida T, Iwakura Y
    • Journal Title

      Nature Communications

      Volume: 6 Issue: 1 Pages: 1-12

    • DOI

      10.1038/ncomms9483

    • NAID

      120006986869

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26450448, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] PGD2 deficiency exacerbates food antigen-induced mast cell hyperplasia.2015

    • Author(s)
      Nakamura T, Maeda S, Horiguchi K, Maehara T, Aritake K, Choi BI, Iwakura Y, Urade Y, Murata T.
    • Journal Title

      Nat Commun

      Volume: 10;6 Issue: 1 Pages: 7514-7514

    • DOI

      10.1038/ncomms8514

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221205, KAKENHI-PROJECT-15J10812, KAKENHI-PROJECT-25460947, KAKENHI-PROJECT-26660225, KAKENHI-PROJECT-25252049, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26293051
  • [Journal Article] CD11c+ DCs accelerate the rejection of older cardiac transplants via IL-17A.2015

    • Author(s)
      Oberhuber, R., Heinbokel, T., Cetina Biefer, H. R., Boenisch, O., Hock, K., Bronson, R. T., Wilhelm, M. J., Iwakura, Y., Edtinger, K., Uehara, H., Quante, M., Voskuil, F., Krenzien, F., Slegtenhorst, B., Abdi, R., Pratschke, J., Elkhal, A., and Tullius, S. G.
    • Journal Title

      Circulation

      Volume: 132 Issue: 2 Pages: 122-131

    • DOI

      10.1161/circulationaha.114.014917

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015

    • Author(s)
      Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.
    • Journal Title

      Blood.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101
  • [Journal Article] NLRP3 deficiency exacerbates hyperoxia-induced lethality through Stat3 signaling independently of interleukin-1β2015

    • Author(s)
      Mizushina, Y., Shirasuna, K., Usui, F., Karasawa, T., Kawashima, A., Kimura, H., Kobayashi, M., Komada, T., Inoue, Y., Mato, N., Yamasawa, H., Latz, E., Iwakura, Y., Kasahara, T., Bando, M., Sugiyama, Y., and Takahashi, M.
    • Journal Title

      J. Biol. Chem.

      Volume: 290(8) Pages: 5065-5077

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.2015

    • Author(s)
      Nakamura, Y., Sato, K., Yamamoto, H., Matsumura, K., Matsumoto, I., Nomura, T., Miyasaka, T., Ishii, K., Kanno, E., Tachi, M., Yamasaki, S., Saijo, S., Iwakura, Y., Kawakami, K.
    • Journal Title

      Infect. Immun.

      Volume: 83(2) Pages: 671-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice.2015

    • Author(s)
      Uryu H, Hashimoto D, Kato K, Hayase E, Matsuoka S, Ogasawara R, Takahashi S, Maeda Y, Iwasaki H, Miyamoto T, Saijo S, Iwakura Y, Hill GR, Akashi K, Teshima T.
    • Journal Title

      blood

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293094
  • [Journal Article] DDCIR is important for bone homeostasis by regulating IFN-γ production in T cells.2015

    • Author(s)
      Maruhashi T*, Kaifu T*, Yabe R, Seno A, Chung SH, Fujikado N, and Iwakura Y
    • Journal Title

      J. Immunol.

      Volume: 194 Issue: 12 Pages: 5681-91

    • DOI

      10.4049/jimmunol.1500273

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26430095, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Interdependence between interleukin-1 and tumor necrosis factor regulates TNF-dependent control of Mycobacterium tuberculosis infection.2015

    • Author(s)
      Di Paolo, N. C., Shafiani, S., Day, T., Papayannoupoulou, T., Russell, D. W., Iwakura, Y., Sherman, D., Urdahl, K., and Shayakhmetov, D. M.
    • Journal Title

      Immunity

      Volume: 43 Issue: 6 Pages: 1125-36

    • DOI

      10.1016/j.immuni.2015.11.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Mouse model for PTPRD associations with WED/RLS and addiction: reduced expansion alters locomotion, sleep behaviors and cocaine-conditioned place preference.2015

    • Author(s)
      Drgonova, J., Walther, D., Wang, K. J., Hartstein, G. L., Lochte, B., Troncoso, J., Uetani, N., Iwakura, Y., and Uhl, G. R.
    • Journal Title

      Mol. Med.

      Volume: 21 Issue: 1 Pages: 717-725

    • DOI

      10.2119/molmed.2015.00017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] IL-1 Receptor Type 2 Suppresses Collagen-Induced Arthritis by Inhibiting IL-1 Signal on Macrophages.2015

    • Author(s)
      Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y.
    • Journal Title

      J Immunol.

      Volume: 194(7) Issue: 7 Pages: 3156-3168

    • DOI

      10.4049/jimmunol.1402155

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15H05787, KAKENHI-PROJECT-24220011
  • [Journal Article] Dectin-2 deficiency promotes Th2 response and mucin production in the lungs after pulmonary infection with Cryptococcus neoformans.2015

    • Author(s)
      Nakamura Y, Sato K, Yamamoto H, Matsumura K, Matsumoto I, Nomura T, Miyasaka T, Ishii K, Kanno E, Tachi M, Yamasaki S, Saijo S, Iwakura Y, Kawakami K.
    • Journal Title

      Infect Immun.

      Volume: 83 Issue: 2 Pages: 671-681

    • DOI

      10.1128/iai.02835-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26670213
  • [Journal Article] CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes.2015

    • Author(s)
      Yabe, R., Shimizu, K., Shimizu, S., Azechi, S., Choi, B. I., Sudo, K., Kubo, S., Nakae, S., Ishigame, H., Kakuta, S., and Iwakura, Y.
    • Journal Title

      Int. Immunol.

      Volume: 27(4) Pages: 169-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation.2014

    • Author(s)
      Lai, C. Y., Yamazaki, S., Okabe, M., Suzuki, S., Maeyama, Y., Iimura, Y., Onodera. M., Kakuta, S., Iwakura, Y., Nojima, M., Otsu, M., and Nakauchi, H.
    • Journal Title

      Stem Cells

      Volume: 32(7) Pages: 1929-1942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Dectin-2 regulates the effector phase of house dust mite-elicited pulmonary inflammation independently from its role in sensitization.2014

    • Author(s)
      Parsons MW, Li L, Wallace AM, Lee MJ, Katz HR, Fernandez JM, Saijo S, Iwakura Y, Austen KF, Kanaoka Y, Barrett NA.
    • Journal Title

      J Immunol.

      Volume: 192 Issue: 4 Pages: 1361-1371

    • DOI

      10.4049/jimmunol.1301809

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
  • [Journal Article] Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in vial infection.2014

    • Author(s)
      .Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y., and Sun, J.
    • Journal Title

      J. Immunol.

      Volume: 192(7) Pages: 3289-3300

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Targeting IL-1b and IL-17A driven inflammation during influenza-induced exacerbations of chronic lung inflammation.2014

    • Author(s)
      Sichelstiel, A., Yadava, K., Trompette, A., Salami, O., Iwakura, Y., Nicod, L. P., and Marsland, B. J.
    • Journal Title

      PLoS One

      Volume: 9(2)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis.2014

    • Author(s)
      Akitsu A, Kakuta S, Saijo S, Iwakura Y.
    • Journal Title

      Exp Anim.

      Volume: 63 Pages: 235-246

    • NAID

      130003391627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293094
  • [Journal Article] Immune complexes inhibit IL-1 secretion and inflammasome activation.2014

    • Author(s)
      Janczy, J. R., Ciraci, C., Haasken, S., Iwakura, Y., Olivier, A. K., Cassel, S. L., and Sutterwala, F. S.
    • Journal Title

      J. Immunol.,

      Volume: 193(10) Pages: 5190-5198

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Chemokine receptor CCR8 is required for lipopolysassharide-triggered cytokine production in mouse peritoneal macrophages.2014

    • Author(s)
      Oshio, T., Kawashima, R., Kawamura, Y. I., Hagiwara, T., Mizutani, N., Okada, T., Otsubo, T., Inagaki-Ohara, K., Matsukawa, A., Haga, T., Kakuta, S., Iwakura, Y., Hosokawa, S., and Dohi, T.
    • Journal Title

      PLoS One

      Volume: 9(4)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] NLRP3 regulates neutrophil functions and contributes to hepatic ischemia-reperfusion injury independently of inflammasomes.2014

    • Author(s)
      Inoue, Y., Shirasuna, K., Kimura, H., Usui, F., Kawashima, A., Karasawa, T., Tago, K., Dezaki, K., Nishimura, S., Sagara, J., Noda, T., Iwakura, Y., Tsutsui, H., Taniguchi, S., Yanagisawa, K., Yada, T., Yasuda, Y., and Takahashi, M.
    • Journal Title

      J. Immunol.

      Volume: 192(9) Pages: 4342-4351

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Excess IL-1 signaling enhances the development of Th17 cells by downregulating TGF-β-induced Foxp3 expression.2014

    • Author(s)
      Ikeda S, Saijo S, Murayama MA, Shimizu K, Akitsu A, Iwakura Y.
    • Journal Title

      J Immunol.

      Volume: 192 Issue: 4 Pages: 1449-1458

    • DOI

      10.4049/jimmunol.1300387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
  • [Journal Article] Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.2014

    • Author(s)
      Chiba, S., Ikushima, H., Ueki, H., Yanai, H., Kimura, Y., Hangai, S., Nishio, J., Negishi, H., Tamura, T., Saijo, S., Iwakura, Y., and Taniguchi T.
    • Journal Title

      Elife

      Volume: 3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Dectin-2 promotes house dust mite-induced Th2 and Th17 cell differentiation and allergic airway inflammation in mice.2014

    • Author(s)
      Norimoto, A., Hirose, K., Iwata, A., Tamachi, T., Yokota, M., Takahashi, K., Saijo, S., Iwakura, Y., and Nakajima, H.
    • Journal Title

      Am. J. Respir. Cell Mol. Biol.

      Volume: 印刷中 Issue: 2 Pages: 201-9

    • DOI

      10.1165/rcmb.2013-0522oc

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-26461184, KAKENHI-PROJECT-26860598
  • [Journal Article] Critical role for inflammasome-independent IL-1b production in osteomyelitis.2014

    • Author(s)
      Lukens, J. R., Gross, J. M., Calabrese, C., Iwakura, Y., Lamkanfi, M., Vogel, P., and Kanneganti, T. D.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 111 Issue: 3 Pages: 1066-1071

    • DOI

      10.1073/pnas.1318688111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] The role of C-type lectin receptors in host defense against microbial pathogens.2014

    • Author(s)
      Yabe, R., Iwakura, Y., and Saijo, S.
    • Journal Title

      Glycoscinece: Biology and Medicine

      Volume: - Pages: 1319-1329

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Dectin-2 promotes house dust mite-induced T helper type 2 and type 17 cell differentiation and allergic airway inflammation in mice.2014

    • Author(s)
      Norimoto A, Hirose K, Iwata A, Tamachi T, Yokota M, Takahashi K, Saijo S, Iwakura Y, Nakajima H.
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: 51(2) Pages: 201-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Rag2-deficient IL-1 receptor antagonist deficient mice are a novel colitis model in which innate lymphoid cell-derived IL-17 is involved in the pathogenesis.2014

    • Author(s)
      Akitsu A., Kakuta S., Saijo S., Iwakura Y.
    • Journal Title

      Exp. Anim.

      Volume: 印刷中

    • NAID

      130003391627

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Gene targeting study reveals unexpected expression of brain expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice.2014

    • Author(s)
      Ito, K., Yamazaki, S., Yamamoto, R., Tajima, Y., Yanagida, A., Kobayashi, T., Kato-Itoh, M., Kakuta, S., Iwakura, Y., Nakauchi, H., and Kamiya, A.
    • Journal Title

      J. Biol. Chem.

      Volume: 289(43) Pages: 29892-29911

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Mast cell-derived IL-1β contributes to uric acid crystal-induced acute arthritis in mice.2014

    • Author(s)
      Reber, L. L., Marichal, T., Sokolove, J., Starkl, P., Gaudenzio, N., Iwakura, Y., Karasuyama, H., Schwartz, L. B., Robinson, W. H., Tsai, M., and Galli, S. J.
    • Journal Title

      Arthritis Rheumatol.,

      Volume: 66(10) Pages: 2881-2891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Persistent release of IL-1s from skin is associated with systemic cardio-vascular disease. Emaciation and systemic amyloidosis: the potential of anti-IL-1 therapy for systemic inflammatory disease.2014

    • Author(s)
      Yamanaka, K., Nakanishim, T., Saito, H., Maruyamam, J., Isoda, K., Yokochi, A., Imanaka-Yoshida, K., Tsuda, K., Kakeda, M., Okamoto, R., Fujita, S., Iwakura, Y., Suzuki, N., Ito, M., Maruyama, K., Gabazza, E. C., Yoshida, T., Shimaoka, M., and Mizutani, H.
    • Journal Title

      PLoS One

      Volume: 9(8)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Rag2-deficient IL-1 receptor antagonist-deficient mice are a novel colitis model in which innate lymphoid cell-derived IL-17 is involved in the pathogenesis.2014

    • Author(s)
      Akitsu, A., Kakuta, S., Saijo, S., and Iwakura, Y.
    • Journal Title

      Exp. Anim.

      Volume: 63(2) Pages: 235-246

    • NAID

      130003391627

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Ectopic cerebellar cell migration causes maldevelopment of purkinje cells and abnormal motor behavior in CXCR4 null mice.2014

    • Author(s)
      Huang, G. J., Edwards, A., Tsai, C. Y., Lee, Y. S., Peng, L., Era, T., Hirabayashi, Y., Tsai, C. Y., Nishikawa, S., Iwakura, Y., Chen, S. J., and Flint, J.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 2 Pages: e86471-e86471

    • DOI

      10.1371/journal.pone.0086471

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.2014

    • Author(s)
      Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, Nishio J, Negishi H, Tamura T, Saijo S, Iwakura Y, Taniguchi T.
    • Journal Title

      eLife

      Volume: 04177 Pages: 04177-04177

    • DOI

      10.7554/elife.04177

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-12J04120, KAKENHI-PROJECT-13J05883, KAKENHI-PROJECT-14F04416, KAKENHI-PROJECT-14J04316, KAKENHI-PROJECT-14J12292, KAKENHI-PLANNED-22114007, KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24590574, KAKENHI-PROJECT-26293094, KAKENHI-PROJECT-26860316
  • [Journal Article] Positive feedback between NF-κB and TNF-α promotes leukemia-initiating cell capacity.2014

    • Author(s)
      Kagoya Y, Yoshimi A, Kataoka K, Nakagawa M, Kumano K, Arai S, Kobayashi H, Saito T, Iwakura Y, Kurokawa M.
    • Journal Title

      J Clin Invest.

      Volume: 124 Issue: 2 Pages: 528-542

    • DOI

      10.1172/jci68101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24790964, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25462359, KAKENHI-PROJECT-25670445, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-26461170, KAKENHI-PROJECT-26860474
  • [Journal Article] The role of C-type lectin receptors in host defense against microbial pathogens.2014

    • Author(s)
      Yabe R, Iwakura Y, Saijo S.
    • Journal Title

      “Glycoscinece: Biology and Medicine”

      Volume: 1 Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293094
  • [Journal Article] Mechanism of pro-tumorigenic effect of BMP-6: Neovascularizatioon involving tumor-associated macrophages and IL-1a.2014

    • Author(s)
      Kwon, S. J., Lee, G. T., Lee, J. H., Iwakura, Y., Kim, W. J., and Kim, I. Y.
    • Journal Title

      Prostate

      Volume: 74 Issue: 2 Pages: 121-133

    • DOI

      10.1002/pros.22734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist.2014

    • Author(s)
      Kobiyama K, Aoshi T, Narita H, Kuroda E, Hayashi M, Tetsutani K, Koyama S, Mochizuki S, Sakurai K, Katakai Y, Yasutomi Y, Saijo S, Iwakura Y, Akira S, Coban C, Ishii KJ.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 111 Issue: 8 Pages: 3086-3091

    • DOI

      10.1073/pnas.1319268111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591145, KAKENHI-PROJECT-25293100, KAKENHI-PROJECT-25670225
  • [Journal Article] Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis.2014

    • Author(s)
      Song, X., Gao, H., Lin, Y., Yao, Y,. Zhu S, Wang J, Liu Y, Yao X, Meng G, Shen N, Shi Y, Iwakura Y, and Qian Y.
    • Journal Title

      Immunity

      Volume: 40(1) Pages: 140-152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Inflammasome-independent IL-1b mediates autoinflammatory diseases in Pstpip2-deficient mice.2014

    • Author(s)
      Cassel, S. L., Janczy, J. R., Bing, X., Wilson, S. P., Olivier, A. K., Otero, J. E., Iwakura, Y., Shayakhmetov, D. M., Bassuk, A. G., Abu-Amer, Y., Brogden, K. A., Burns, T. L., Sutterwala, F. S., and Ferguson, P. J.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 111 Issue: 3 Pages: 1072-1077

    • DOI

      10.1073/pnas.1318685111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin.2014

    • Author(s)
      Natsuaki, Y., Egawa, G., Nakamizo, S., Ono, S., Hanakawa, S., Okada, T., Kusuba, N., Otsuka, A., Kitoh, A., Honda, T., Nakajima, S., Tsuchiya, S., Sugimoto, Y., Ishii, K. J , Tsutsui, H., Yagita, H., Iwakura, Y., Kubo, M., Ng, L. G., Hashimoto, T., Fuentes, J., Guttman-Yassky, E., Miyachi, Y., and Kabashima, K.
    • Journal Title

      Nat. Immunol.

      Volume: 15(11) Pages: 1064-1069

    • NAID

      120005477231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Multiple CD11c+ cells collaboratively express IL-1β to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.2014

    • Author(s)
      Benahmed, F., Chyou, S., Dasoveanu, D., Chen, J., Kumar, V., Iwakura, Y., and Lu, T. T.
    • Journal Title

      J. Immunol.

      Volume: 192(9) Pages: 4153-4163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis.2014

    • Author(s)
      Akitsu A, Kakuta S, Saijo S, Iwakura Y.
    • Journal Title

      Exp Anim.

      Volume: 63 Pages: 235-246

    • NAID

      130003391627

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23390101
  • [Journal Article] Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.2014

    • Author(s)
      Wu, L., Ong, S., Talor, M. V., Barin, J. G., Baldeviano, G. C, Kass,D.A., Bedja, D., Zhang, H., Sheikhm, A., Margolick, J. B., Iwakura, Y., Rose, N. R., and Cihakova, D.
    • Journal Title

      J. Exp. Med.

      Volume: 211(7) Pages: 1449-1464

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] An ITAM-Syk-CARD9 signaling axis triggers contact hypersensitivity by stimulating IL-1 production in dendritic cells.2014

    • Author(s)
      Yasukawa, S., Miyazaki, Y., Yoshii, C., Nakaya, M., Ozaki, N., Toda, S., Kuroda, E., Ishibashi, K., Yasuda, T., Natsuaki, Y., Mi-Ichi, F., Iizasa, E., Nakahara, T., Yamazaki, M., Kabashima, K., Iwakura, Y., Takai, T., Saito, T., Kurosaki, T., Malissen, B., Ohno, N., Furue, M., Yoshida, H., and Hara, H.
    • Journal Title

      Nat. Commun.,

      Volume: 5 Pages: 3755-3755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock.2014

    • Author(s)
      Shimura, E., Shibui, A., Narushima, S., Nambu, A., Yamaguchi, S., Akitsu, A., Leonard, W. J., Iwakura, Y., Matsumoto, K., Suto, H., Okumura, K., Sudo, K., and Nakae, S.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 453(1) Pages: 1-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Involvement of IL-17A-induced hypercontractility of intestinal smooth muscle cells in persistent gut moter dysfunction.2014

    • Author(s)
      Akiho, H., Tokita, Y., Nakamura, K., Satoh, K., Nishiyama, M., Tsuchiya, N., Tsuchiya, K., Ohbuchi, K., Iwakura, Y., Ihara, E., Takayanagi, R., and Yamamoto, M.
    • Journal Title

      PLoS One

      Volume: 9(5)

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor2014

    • Author(s)
      Seno A, Maruhashi T, Kaifu T, Yabe R, Fujikado N, Ma G, Ikarashi T, Kakuta S, Iwakura Y
    • Journal Title

      Experimental Animals

      Volume: Epub

    • NAID

      130005069862

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Journal Article] Interleukin-1 receptor antagonist originating from bone marrow-derived cells and non-bone marrow-derived cells helps to suppress arterial inflammation and reduce neointimal formation after injury.2014

    • Author(s)
      Isoda, K., Akita, K., Isobe, S., Niida, T., Adachi, T., Iwakura, Y., and Daida, H.
    • Journal Title

      J. Atheroscler. Thromb.

      Volume: 21(11) Pages: 1208-1218

    • NAID

      130004690941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Multiple CD11c+ cells collaboratively express IL-1b to modulate stromal vascular endothelial growth factor and lymph node vascular-stromal growth.2014

    • Author(s)
      Benahmed, F., Chyou, S., Dasoveanu, D., Chen, J., Kumar, V., Iwakura, Y., and Lu, T. T.
    • Journal Title

      J. Immunol.

      Volume: 印刷中 Issue: 9 Pages: 4153-4163

    • DOI

      10.4049/jimmunol.1301765

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Involvement of Gr-1dull+ cellsin the production of TNF-a and IL-17 and exacerbated systemic inflammatory response caused by lipopolysaccharide.2014

    • Author(s)
      Tanno, D., Akahori, Y., Toyama, M., Sato, K., Kudo, D., Abe, Y., Miyasaka, T., Yamamoto, H., Ishii, K., Kanno, E., Maruyama, R., Kushimoto, S., Iwakura, Y., and Kawakami, K.
    • Journal Title

      Inflammation

      Volume: 37 Issue: 1 Pages: 186-195

    • DOI

      10.1007/s10753-013-9729-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-17A as an inducer for Th2 immune responses in murine atopic dermatitits models.2014

    • Author(s)
      Nakajima, S., Kitoh, A., Egawa, G., Natsuaki, Y., Nakamizo, S., Sagita, Moniaga, C., Otsuka, A., Honda, T., Hanakawa, S., Amano, W., Iwakura, Y., Nakae, S., Kubo, M., Miyachi, Y., and Kabashima, K.
    • Journal Title

      J. Invest. Dermatol.

      Volume: 134(8) Pages: 2122-2130

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Cigarette smoke primes the pulmonary environment to IL-1α/CXCR-2-dependent nontypeable haemophilus influenzae-exacerbated neutrophillia in mice.2014

    • Author(s)
      Nikota, J. K., Shen, P., Morissette, M. C., Fernandes, K., Roos, A., Chu, D. K., Barra, N. G., Iwakura, Y., Kolbeck, R., Humbles, A. A., and Stampfli, M. R.
    • Journal Title

      J. Immunol.

      Volume: 193(6) Pages: 3134-3145

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in vial infection.2014

    • Author(s)
      Jie, Z., Liang, Y., Hou, L., Dong, C., Iwakura, Y., Soong, L., Cong, Y., and Sun, J.
    • Journal Title

      J. Immunol.

      Volume: 192 Issue: 7 Pages: 3289-3300

    • DOI

      10.4049/jimmunol.1303281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] CTRP3 plays an important role in the development of collagen-induced arthritis in mice.2014

    • Author(s)
      Murayama MA, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 443 Issue: 1 Pages: 42-48

    • DOI

      10.1016/j.bbrc.2013.11.040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488
  • [Journal Article] Dectin-2 promotes house dust mite-induced Th2 and Th17 cell differentiation and allergic airway inflammation in mice.2014

    • Author(s)
      Norimoto A, Hirose K, Iwata A, Tamachi T, Yokota M, Takahashi K, Saijo S, Iwakura Y, Nakajima H.
    • Journal Title

      Am J Respir Cell Mol Biol.

      Volume: Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101
  • [Journal Article] Defect of CARD9 leads to impaired accululation of IFN-g-producing memory-phenotype T cells in lungs and increased susceptibility to pulmonary infection with Cryptococcus neoformans.2014

    • Author(s)
      Yamamoto, H., Nakamura, Y., Sato, K., Takahashi, Y., Nomura, T., Miyasaka, T., Ishii, K., Hara, H., Yamamoto, N., Kanno, E., Iwakura, Y., and Kawakami, K.
    • Journal Title

      Infect. Immun.

      Volume: 82(4) Pages: 1606-1615

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Obesity-induced gut microbial metabolite prootes liver cancer through senescence secretome.2013

    • Author(s)
      Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., Honda, K., Ishikawa, Y., Hara, E., and Ohtani, N.
    • Journal Title

      Nature

      Volume: 499 Issue: 7488 Pages: 97-101

    • DOI

      10.1038/nature13004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] MFGE8 inhibits inflammasome-induced IL-1b production and limits postischemic cerebral injury.2013

    • Author(s)
      Deroide, N., Li, X., Lerouet, D., Van Vre, E., Baker, L., Harrison, J., Poittevin, M. Masters, L., Nih, L., Margaill, I., Iwakura, Y., Ryffel, B., Pocard, M., Tedgui, A., Kubis, N., and Mallat, Z.
    • Journal Title

      J. Clin. Invest.

      Volume: 123 Issue: 3 Pages: 1176-1181

    • DOI

      10.1172/jci65167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] The Arf GAP SMAP2 is necessary for organized vesicle budding from the trans-Golgi network and subsequent acrosome formation in spermiogenesis.2013

    • Author(s)
      Funaki T, Kon S, Tanabe K, Natsume W, Sato S, Shimizu T, Yoshida N, Wong WF, Ogura A, Ogawa T, Inoue K, Ogonuki N, Miki H, Mochida K, Endoh K, Yomogida K, Fukumoto M, Horai R, Iwakura Y, Ito C, Toshimori K, Watanabe T, Satake M.
    • Journal Title

      Mol. Biol. Cell

      Volume: 24 Issue: 17 Pages: 2633-44

    • DOI

      10.1091/mbc.e13-05-0234

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23113721, KAKENHI-PROJECT-23501256, KAKENHI-PROJECT-23770148, KAKENHI-PUBLICLY-24112706, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24570159, KAKENHI-PROJECT-24592441, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293041, KAKENHI-PROJECT-25670087
  • [Journal Article] Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse.2013

    • Author(s)
      Kuriya G, Uchida T, Akazawa S, Kobayashi M, Nakamura K, Satoh T, Horie I, Kawasaki E, Yamasaki H, Yu L, Iwakura Y, Sasaki H, Nagayama Y, Kawakami A, Abiru N.
    • Journal Title

      Diabetologia

      Volume: 56 Issue: 8 Pages: 1773-1780

    • DOI

      10.1007/s00125-013-2935-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23791060, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591334
  • [Journal Article] IL-17A promotes macrophage effector mechanisms against Trypanosoma cruzi by trapping parasites in the endolysosomal compartment.2013

    • Author(s)
      Erdmann, H., RoBnagel, C., Bohme, J., Iwakura, Y., Jacobs, T., Schaible, U. E., and Holscher, C.
    • Journal Title

      Immunobiology

      Volume: 218, Issue: 6 Pages: 910-923

    • DOI

      10.1016/j.imbio.2012.10.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice2013

    • Author(s)
      Etsuko Kurimoto
    • Journal Title

      Respiratory Research

      Volume: 14 Issue: 1 Pages: 5-5

    • DOI

      10.1186/1465-9921-14-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590526, KAKENHI-PROJECT-22591092, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-25860644
  • [Journal Article] Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells.2013

    • Author(s)
      Tada, T., Kadoki, M., Yang, L., Tokunaga, K. and Iwakura, Y.
    • Journal Title

      Front. Microbiol.

      Volume: 4 Pages: 377-377

    • DOI

      10.3389/fmicb.2013.00377

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24790992
  • [Journal Article] Dectin-2-dependent NKT cell activation and serotype-specific antibody production in mice immunized with pneumococcal polysaccharide vaccine.2013

    • Author(s)
      Miyasaka T, Akahori Y, Toyama M, Miyamura N, Ishii K, Saijo S, Iwakura Y, Kinjo Y, Miyazaki Y, Oishi K, Kawakami K.
    • Journal Title

      PLoS One.

      Volume: 8 Issue: 10 Pages: e78611-e78611

    • DOI

      10.1371/journal.pone.0078611

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-24220011
  • [Journal Article] Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation.2013

    • Author(s)
      Silverpil, E., Wright, A. K., Hansson, M., Jirholt, P., Henningsson, L., Smith, M. E., Gordon, S. B., Iwakura, Y., Gjertsson, I., Glader, P., and Linden, A.
    • Journal Title

      Innate Immun.

      Volume: 19 Issue: 5 Pages: 479-492

    • DOI

      10.1177/1753425912470470

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages2013

    • Author(s)
      Ishida H, Imai T, Suzue K, Hirai M, Taniguchi T, Yoshimura A, Iwakura Y, Okada H, Suzuki T, Shimokawa C, and Hisaeda
    • Journal Title

      Eur. J. Immunol.

      Volume: 43 Issue: 10 Pages: 2696-2706

    • DOI

      10.1002/eji.201343493

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24117504, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24790399, KAKENHI-PROJECT-25670226
  • [Journal Article] Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.2013

    • Author(s)
      Schmitt, E. G., Haribhai, D., Jeschke, J. C., Co, D. O., Ziegelbauer, J., Yan, K., Iwakura, Y., Mishra, M. K., Simpson, P., Salzman, N. H., and Williams, C. B.
    • Journal Title

      J. Immunol.

      Volume: 191 Issue: 11 Pages: 5460-5476

    • DOI

      10.4049/jimmunol.1301576

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Mature Dendritic Cell Suppression by IL- 1 Receptor Antagonist on Retinal Pigment Epithelium Cells2013

    • Author(s)
      Sugita S, Kawazoe Y, Imai A, Usui Y, Iwakura Y, Isoda K, Ito M, Mochizuki M
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 54巻 Issue: 5 Pages: 3240-3249

    • DOI

      10.1167/iovs.12-11483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591957, KAKENHI-PROJECT-24220011
  • [Journal Article] Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation2013

    • Author(s)
      Soeno Y, Fujita K, Kudo T, Asagiri M, Kakuta S, Taya Y, Shimazu Y, Sato K, Tanaka-Fujita R, Kubo S, Iwakura Y, Nakamura Y, Mori S, and Aoba T
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 8 Pages: e72105-e72105

    • DOI

      10.1371/journal.pone.0072105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592716, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24592780, KAKENHI-PROJECT-24659822, KAKENHI-PROJECT-24689056, KAKENHI-PROJECT-25462935, KAKENHI-PROJECT-25463154
  • [Journal Article] Vaspin inhibits apoptosis of endothelial cells as a ligand for cell-surface GRP78/VDAC complex.2013

    • Author(s)
      Nakatsuka A
    • Journal Title

      Cir Res

      Volume: 112(5) Issue: 5 Pages: 771-780

    • DOI

      10.1161/circresaha.111.300049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249053, KAKENHI-PROJECT-23390241, KAKENHI-PROJECT-23659470, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24790926, KAKENHI-PUBLICLY-23114504, KAKENHI-PUBLICLY-23126516
  • [Journal Article] C-Type lectin is an FcRr-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor2013

    • Author(s)
      Miyake Y, Ynmasaki S, et al.
    • Journal Title

      Immunity

      Volume: 38 Issue: 5 Pages: 1050-62

    • DOI

      10.1016/j.immuni.2013.03.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11F01107, KAKENHI-PROJECT-22590875, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24791552, KAKENHI-PROJECT-25461178, KAKENHI-PUBLICLY-23114504
  • [Journal Article] Colitogenic effector T cells: roles of gut-homing integrin, gut antigen specificity and gd T cells.2013

    • Author(s)
      Do, J. S., Visperas, A., Freeman, M. L., Iwakura, Y., Oukka, M., and Min, B.
    • Journal Title

      Immunol. Cell Biol.

      Volume: 92 Issue: 1 Pages: 90-98

    • DOI

      10.1038/icb.2013.70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Fatty acid-inudced mitochondrial uncoupling elicits inflammasome-independent IL-1a and sterile vascular inflammation in atherosclerosis.2013

    • Author(s)
      Freigang, S., Ampenberger, F., Weiss, A., Kanneganti, T. D., Iwakura, Y., Hersberger, M., and Kopf, M.
    • Journal Title

      Nat. Immunol.

      Volume: 14 Issue: 10 Pages: 1045-1053

    • DOI

      10.1038/ni.2704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Pam3CSK4 enhanced beta cell loss and diabetogenesis: The roles of IFN-gamma and IL-17.2013

    • Author(s)
      Al Shamsi, M., Shahin, A., Iwakura, Y., Lukic, M. L., and Mensah-Brown, E. P.
    • Journal Title

      Clin. Immunol.

      Volume: 149 Issue: 1 Pages: 86-96

    • DOI

      10.1016/j.clim.2013.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Hypoxia enhances innate immune activation to Aspergillus fumigatus through cell wall modulation.2013

    • Author(s)
      Shepardson, K. M., Ngo, L. Y., Aimanianda, V., Latge, J.-P., Barker, B. M., Blosser, S. J., Iwakura, Y., Hohl, T. M., and Cramer, R. A.
    • Journal Title

      Microbe. Infect.

      Volume: 15 Issue: 4 Pages: 259-269

    • DOI

      10.1016/j.micinf.2012.11.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-17A mediates early post-translpant lesions agter teterotopic trachea allotransplantation in mice.2013

    • Author(s)
      Lemaitre, P. H., Vokaer, B., Charbonnier, L. M., Iwakura, Y., Estenne, M., Goldman, M., Leo, O., Remmelink, M., and Le Moine, A.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 7 Pages: e70236-e70236

    • DOI

      10.1371/journal.pone.0070236

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Regulatory T cells are strong promoters of acute ischemia stroke in mice by inducing dysfunction of the cerebral microvasculature.2013

    • Author(s)
      Kleinschnitz, C., Kraft, P., Dreykluft, A., Hagedorn, I., Gobel, K., Schuhmann, M. K., Langhauser, F., Helluy, X., Schwarz, T., Bittner, S., Mayer, C. T., Brede, M., Varallyay. C., Pham, M., Bendszus, M., Jakob, P., Magnus, T., Meuth, S. G., Iwakura, Y., Zernecke, A. et al.
    • Journal Title

      Blood

      Volume: 121 Issue: 4 Pages: 679-691

    • DOI

      10.1182/blood-2012-04-426734

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia.2013

    • Author(s)
      Kon et al.
    • Journal Title

      J. Clin. Invest.

      Volume: 123 Issue: 3 Pages: 1123-1137

    • DOI

      10.1172/jci63711

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501256, KAKENHI-PROJECT-23770137, KAKENHI-PROJECT-23770148, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659458
  • [Journal Article] Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis.2013

    • Author(s)
      Chang, Y., Al-Alwan, L., Audusseau, S., Chouiali, F., Carlevaro-Fita, J., Iwakura, Y., Baglole, C. J., Eidelman, D. H., and Hamid, Q.
    • Journal Title

      Am. J. Physiol. Lung Cell Mol. Physiol.

      Volume: 306 Issue: 2 Pages: L132-L143

    • DOI

      10.1152/ajplung.00111.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] RIP1-driven autoinflammation targets IL-1a independently of inflammasomes and RIP3.2013

    • Author(s)
      Lukens, J. R., Vogel, P., Johnson, G. R., Kelliher, M. A., Iwakura, Y., Lamkanfi, M., and Kanneganti, T. D.
    • Journal Title

      Nature

      Volume: 498 Issue: 7453 Pages: 224-227

    • DOI

      10.1038/nature12174

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilliate obesity-associated airway hyperreactivity.2013

    • Author(s)
      Kim, H. Y., Lee, H. J., Chang, Y. J., Pichavant, M., Shore, S. A., Fitzgerald, K. A., Iwakura, Y., Israel, E., Bolger, K., Faul, J., Dekruyff, R. H., and Umetsu, D. T.
    • Journal Title

      Nat. Med.

      Volume: 20 Issue: 1 Pages: 54-61

    • DOI

      10.1038/nm.3423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Cyclosporine A drives a Th17- and Th2-mediated posttransplant obliterative airway disease.2013

    • Author(s)
      Lemaitre, P. H., Vokaer, B., Charbonnier, L. M., Iwakura, Y., Field, K. A., Estenne, M., Goldman, M., Leo, O., Remmelink, M., and Le Moine, A.
    • Journal Title

      Am. J. Transplant.

      Volume: 13 Issue: 3 Pages: 611-620

    • DOI

      10.1111/ajt.12067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Interleukin-1b induced by Helicobacter pylori infection enhances mouse gastric carcinogenesis.2013

    • Author(s)
      Shigematsu, Y., Niwa, T., Rehnberg, E., Toyoda, T., Yoshida, S., Mori, A., Wakabayashi, M., Iwakura, Y., Ichinose, M., Kim, Y. J., and Ushijima, T.
    • Journal Title

      Cancer Lett.

      Volume: 340 Issue: 1 Pages: 141-147

    • DOI

      10.1016/j.canlet.2013.07.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Evaluation of Kampo medicines used to treat rheumatoid arthritis in collagen-induced arthritic and pX transgenic mice.2013

    • Author(s)
      Ono, Y., Ogihara, Y., Saijo, S., Iwakura, Y., and Inoue, M.
    • Journal Title

      Mod. Rheumatol.

      Volume: 13 Issue: 1 Pages: 50-56

    • DOI

      10.3109/s101650300007

    • NAID

      10015486726

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] Neutrophils are essential as a source of IL-17 in the effector phase of arthritis.2013

    • Author(s)
      Katayama, M., Ohmura, K., Yukawa, N., Terao, C., Hashimoto, M., Yoshifuji, H., Kawabata, D., Fujii, T., Iwakura, Y., and Mimori, T.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 12

    • DOI

      10.1371/annotation/5fedb3bf-c9c2-4862-9ad5-23c8ae484ad5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] 遺伝子改変マウスによる疾患発症機構の解析.2013

    • Author(s)
      岩倉洋一郎
    • Journal Title

      感染・炎症・免疫

      Volume: 43 Pages: 313-319

    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-22+CD4+T細胞による大腸炎誘導と抑制.2013

    • Author(s)
      角木基彦、岩倉洋一郎
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 59 Pages: 405-410

    • NAID

      40019636556

    • Data Source
      KAKENHI-PROJECT-24220011
  • [Journal Article] IL-1 signaling is dispensable for protective immunity in Leishmania-resistant mice2011

    • Author(s)
      Kautz-Neu, K., Kostka, S. L., Dinges, S., Iwakura, Y., Udey, M. C., and Von Stebut, E.
    • Journal Title

      Exp. Dermatol.

      Volume: 20 Pages: 76-78

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Functional specialization of interleukin-17 family members2011

    • Author(s)
      Iwakura, Yoichiro
    • Journal Title

      Immunity

      Volume: 34 Pages: 149-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21022016
  • [Journal Article] G. Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation2011

    • Author(s)
      Rivera, A., Hohl, T. M., Collins, N., Leiner, I., Gallegos, A., Saijo, S., Coward, J. W., Iwakura, Y., and Pamer, E.
    • Journal Title

      J. Exp. Med.

      Volume: 208 Pages: 369-381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Desmoglein 3-specific CD4+T cells induce pemphigus vulgaris and interface dermatitis in mice2011

    • Author(s)
      Takahashi, H., Kouno, M., Nagao, K., Wada, N., Hata, T., Nishimoto, S., Iwakura, Y., Yoshimura, A., Yamada, T., Kuwana, M., Fujii, H., Koyasu, S., and Amagai, M.
    • Journal Title

      J. Clin. Invest.

      Volume: 121 Pages: 3677-3688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Functional specialization of interleukin-17 family members.2011

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Immunity

      Volume: 34 Pages: 149-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] IL-1 receptor accessory protein-like 1 associated with mental retardation and autism mediates synapse formation by trans-synaptic interaction with protein tyrosine phosphatase2011

    • Author(s)
      Yoshida, T., Yasumura, M., Uemura, T., Lee, S. J., Ra, M., Taguchi, R., Iwakura, Y., and Mishina, M.
    • Journal Title

      J. Neurosci.

      Volume: 31 Pages: 13485-13499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Control of T(H) 17 cells occurs in the small intestine2011

    • Author(s)
      Esplugues, E., Huber, S., Gagliani, N., Hauser, A. E., Town, T., Wan, Y. Y., O' Connor, W., Rongvaux, A., Van Rooijen, N., Haberman, A. M., Iwakura, Y., Kuchroo, V. K., Kolls, J. K., Bluestone, J. A., Herold, K. C., and Flavell, R. A.
    • Journal Title

      Nature

      Volume: 475 Pages: 514-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Dectin-1 and Dectin-2 in innate immunity against fungi2011

    • Author(s)
      Saijo, S., and Iwakura, Y.
    • Journal Title

      Int. Immunol.

      Volume: 23 Pages: 467-472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Functional specialization of IL-17 family members2011

    • Author(s)
      Iwakura, Y., Ishigame, H., Saijo, S., and Nakae, S.
    • Journal Title

      Immunity

      Volume: 34 Pages: 149-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Local microbleeding facilitates IL-6-and IL-17-dependent arthritis in the absence of tissue antigen recognition by activated T cells2011

    • Author(s)
      Murakami, M., Okuyama, Y., Ogura, H., Asano, S., Arima, Y., Tsuruoka, M., Harada, M., Kanamoto, M., Sawa, Y., Iwakura, Y., Takatsu, K., Kamimura, D., and Hirano, T.
    • Journal Title

      J. Exp. Med.

      Volume: 208 Pages: 103-114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] The role of glucocorticoids in pregnancy, parturition, lactation, and nurturing in melanocortin receptor 2. deficient mice2011

    • Author(s)
      Chida, D., Miyoshi, K., Sato, T., Yoda, T., Kikusui, T., and Iwakura, Y.
    • Journal Title

      Endocrinology

      Volume: 152 Pages: 1652-1660

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Memory/effector(CD45RBlo) CD4 T cells are controlled directly by IL-10 and cause IL-22-dependent intestinal pathology2011

    • Author(s)
      Kamanaka, M., Huber, S., Zenewicz, L. A., Gagliani, N., Rathinam, C., O' Connor, W. Jr., Wan, Y. Y., Nakae, S., Iwakura, Y., Hao, L., and Flavell, R. A.
    • Journal Title

      J. Exp. Med.

      Volume: 208 Pages: 1027-1040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1B and by down-regulation of suppressor of cytokine signaling 1(SOCS1)2011

    • Author(s)
      Shikama, Y., Kuroishi, T., Nagai, Y., Iwakura, Y., Shimauchi, H., Takada, H., Sugawara, S., and Endo, Y.
    • Journal Title

      Innate Immun.

      Volume: 17 Pages: 54-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Functional recovery after peripheral nerve injury is dependent on the proinflammatory cytokines IL-1. and TNF : implicaitons for neuropathic pain2011

    • Author(s)
      Nadeau, S., Filali, M., Zhang, J., Kerr, B. J., Rivest, S., Soulet, D., Iwakura, Y., de Rivero Vaccari, J. P., Keane, R. W., and Lacroix, S.
    • Journal Title

      J. Neurosci.

      Volume: 31 Pages: 12533-12542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Functional specialization of interleukin-17 family members2011

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Immunity

      Volume: 34 Issue: 2 Pages: 149-62

    • DOI

      10.1016/j.immuni.2011.02.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390101, KAKENHI-PROJECT-21390303
  • [Journal Article] M. Type I interferon signaling constrains IL-17A/F secretion byγδT cells during bacterial infection2010

    • Author(s)
      Henry, T., Kirimanjeswara, G. S., Ruby, T., Jones, J. W., Peng, K., Perret, M., Ho, L., Sauer, J.-D., Iwakura, Y., Metzger, D. W., and Monack, D.
    • Journal Title

      J. Immunol.

      Volume: 184 Pages: 3755-3767

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Essential role of IL-17A in the formation of a mycobacterial infection-induced granuloma in the lung2010

    • Author(s)
      Okamoto Yoshida, Y., Umemura, M., Yahagi, A., O' Brien, R. L., Ikuta, K., Kishihara, K., Hara, H., Nakae, S., Iwakura, Y., and Matsuzaki, G.
    • Journal Title

      J. Immunol.

      Volume: 184 Pages: 4414-4422

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction.2010

    • Author(s)
      Madhur, M.S., Lob, H.E., McCann, L.A., Iwakura, Y., Blinder, Y., Guzik, T.J., Harrison, D.G.
    • Journal Title

      Hypertension 55

      Pages: 500-507

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy.2010

    • Author(s)
      Baldeviano, G.C., Barin, J.G., Talor, M.V., Srinivasan, S., Bedja, D., Zheng, D., Gabrielson, K., Iwakura, Y., Rose, N.R., Cihakova, D.
    • Journal Title

      Circulation Res. 106

      Pages: 1645-1655

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IFN-γis a master regulator of endotoxin shock syndrome in mice primed with heat-killed Propionibacterium acnes.2010

    • Author(s)
      Kawa, K., Tsutsui, H., Uchiyama, R., Kato, J., Matsui, K., Iwakura, Y., Matsumoto, T., Nakanishi, K.
    • Journal Title

      Int. Immunol. 22

      Pages: 157-166

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Nucleoprotein diet ameliorates arthritis symptoms in mice transgenic for human T-cell leukemia virus type I (HTLV-I).2010

    • Author(s)
      Ohtaki, H., Yufu, S., Nakamachi, T., Satoh, K., Shimizu, A., Mori, H., Sato, A., Iwakura, Y., Matsunaga, M., Shioda, S.
    • Journal Title

      J. Clin. Biochem. Nutr. 46

      Pages: 93-104

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17 is necessary for host protection against acute-phase Trypanosoma cruzi infection2010

    • Author(s)
      Miyazaki, Y., Hamano, S., Wang, S., Shimanoe, Y., Iwakura, Y., and Yoshida, H.
    • Journal Title

      J. Immunol.

      Volume: 185 Pages: 1150-1157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Type I interferon signaling constrains IL-17A/F secretion by gd T cells during bacterial infection.2010

    • Author(s)
      Henry, T., Kirimanjeswara, G.S., Ruby, T., Jones, J.W., Peng, K., Perret, M., Ho, L., Sauer, J. -D., Iwakura, Y., Metzger, D.W., Monack, D.M.
    • Journal Title

      J. Immunol. 184

      Pages: 3755-67

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-23 suppresses innate immune response independently of IL-17A during carcinogenesis and metastasis.2010

    • Author(s)
      Teng, M.W.L., Andrews, D.M., McLaughlin, N., von Scheidt, B., Ngiow, S.F., Moller, A., Hill, G.R., Iwakura, Y., Oft, M., Smyth, M.J.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 107

      Pages: 8328-33

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] D. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis2010

    • Author(s)
      Chou, R. C., Kim, N. D., Sadik, C. D., Seung, E., Lan, Y., Byrne, M. H., Haribabu, B., Iwakura, Y., and Luster, A.
    • Journal Title

      Immunity

      Volume: 33 Pages: 266-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Stem cell mobilization with G-CSF induces Type-17 differentiation and promotes scleroderma.2010

    • Author(s)
      Hill, G.R., Olver, S.D., Kuns, R.D., Varelias, A., Raffelt, N.C., Don, A.L.J., Markey, K.A., Wilson, Y.A., Smyth, M.J., Iwakura, Y., Tocker, J., Clouston, A., MacDonald, K.P.A.
    • Journal Title

      Blood 30(Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Lung CD4-CD8-double-negative T cells are prominent producers of IL-17A and IFN-gamma during primary respiratory murine infection with Francisella tularensis live vaccine strain.2010

    • Author(s)
      Cowley, S.C., Meierovics, A.I., Frelinger, J.A., Iwakura, Y., Elkins, K.L.
    • Journal Title

      J. Immunol. 184

      Pages: 5791-5801

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IFN-γregulates the requirement for IL-17 in proteoglycan-induced arthritis.2010

    • Author(s)
      Doodes, P.D., Cao, Y., Hamel, K.M., Wang, Y., Rodeghero, R.I., Mikecz, K., Glant T.T., Iwakura, Y., Finnegan, A.
    • Journal Title

      J. Immunol. 184

      Pages: 1552-1559

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.2010

    • Author(s)
      Kono, H., Karmarkar, D., Iwakura, Y., Rock, K.L.
    • Journal Title

      J. Immunol. 184

      Pages: 4470-8

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Dectin-2 recognition ofα-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans2010

    • Author(s)
      Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., and Iwakura,
    • Journal Title

      Immunity

      Volume: 32 Pages: 681-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Dectin-2 recognition of α-mannans and induction of Th17 differentiation is essential for host defense against Candida albicans.2010

    • Author(s)
      Saijo, S., Ikeda, S., Yamabe, K., Kakuta, S., Ishigame, H., Akitsu, A., Fujikado, N., Kusaka, T., Kubo, S., Chung, S., Komatsu, R., Miura, N., Adachi, Y., Ohno, N., Shibuya, K., Yamamoto, N., Kawakami, K., Yamasaki, S., Saito, T., Akira, S., Iwakura, Y.
    • Journal Title

      Immunity 32

      Pages: 1-11

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells spport the progression of tumor via promoting angiogenesis.2010

    • Author(s)
      Wakita, D., Sumida, K., Iwakura, Y., Nishikawa, H., Ohkuri, T., Chamoto, K., Kitamura, H., Nishimura, T.
    • Journal Title

      Eur. J. Immunol. 15(Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Activation of myeloid dendritic cells by deoxynucleic acids from Cordyceps sinensis via a Toll-like receptor 9-dependent pathway.2010

    • Author(s)
      Xiao, G., Miyazato, A., Abe, Y., Zhang, T., Nakamura, K., Inden, K., Tanaka, M., Tanno, D., Miyasaka, T., Ishii, K., Takeda, K., Akira, S., Saijo, S., Iwakura, Y., Adachi, Y., Ohno, N., Yamamoto, N., Kunishima, H., Hirakata, Y., Kaku, M., Kawakami, K.
    • Journal Title

      Cellular Immunol. 263

      Pages: 241-250

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Neural tube defects and impaired neural progenitor cell proliferation in G. 1-deficient mice2010

    • Author(s)
      Okae, H., and Iwakura, Y.
    • Journal Title

      Developmental Dynamics

      Volume: 239 Pages: 1089-1101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Th17 cells promote autoimmune anti-myeloperoxidase glomerulomephritits.2010

    • Author(s)
      Gan, P.Y., Steinmetz, O.M., Tan, D.S., O'Sullivan, K.M., Ooi, J.D., Iwakura, Y., Kitching, A.R., Holdsworth, S.R.
    • Journal Title

      J. Am. Soc. Nephrol. 21

      Pages: 925-931

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn^<-/-> mice2010

    • Author(s)
      Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Nakae, S., Ishigame, H., Kakuta, S., Saijo, S., and Iwakura, Y.
    • Journal Title

      J. Immunol.

      Volume: 185 Pages: 1887-1893

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] L. Lung CD4-CD8-double-negative T cells are prominent producers of IL-17A and IFN-during primary respiratory murine infection with Francisella tularensis live vaccine strain2010

    • Author(s)
      Cowley, S. C., Meierovics, A. I., Frelinger, J. A., Iwakura, Y., and Elkins, K.
    • Journal Title

      J. Immunol.

      Volume: 184 Pages: 5791-5801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] CXC chemokine receptor 4 expressed in T cells plays an important role in the development of collagen-induced arthritis2010

    • Author(s)
      Chung, S. H., Seki, K., Choi, B. I., Kimura, K. B., Ito, A., Fujikado, N., Saijo, S., and Iwakura, Y.
    • Journal Title

      Arthritis Res. Ther.

      Volume: 12 Pages: 188-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] IL-17 contributes to the development of chronic rejection in a murine-heart transpant model.2010

    • Author(s)
      Itoh, S., Nakae, S., Axtell, R.C., Velotta, J.B., Kimura, N., Kajiwara, N., Iwakura, Y., Saito, H., Adachi, H., Steinman, L., Robbins, R.C., Fishbein, M.P.
    • Journal Title

      J. Clin. Immunol. 30

      Pages: 235-40

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-17A upregulates receptor activator of NF-kappaB on osteoclast precursors.2010

    • Author(s)
      Adamopoulos, I.E., Chao, C.C., Geissler, R., Laface, D., Blumenschein, W., Iwakura, Y., McClanahan, T., Bowman, E.P.
    • Journal Title

      Arthritis Res. Ther. 12

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] A Th17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-g production in order to induce airway hyperresponsiveness.2010

    • Author(s)
      Ashino, S., Wakita, D., Shiohama, Y., Iwakura, Y., Chamoto, K., Ohkuri, T., Kitamura, H., Nishimura, T.
    • Journal Title

      Int. Immunol. 22

      Pages: 503-513

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Deficiency of interleukin-1 receptor antagonist induces aortic valve disease in BALB/c mice.2010

    • Author(s)
      Isoda, K., Matsuki, T., Kondo, H., Iwakura, Y., Ohsuzu, F.
    • Journal Title

      Arterioscler. Thromb. Vasc. Biol. 30

      Pages: 708-15

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-1 plays an important role in the bone metabolism under physiological conditions2010

    • Author(s)
      Lee, Y.-M., Fujikado, N., Manaka, H., Yasuda, H., and Iwakura, Y.
    • Journal Title

      Int. Immunol.

      Volume: 22 Pages: 805-816

    • NAID

      10027907526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] IFN-regulates the requirement for IL-17 in proteoglycan-induced arthritis2010

    • Author(s)
      Doodes, P. D., Cao, Y., Hamel, K. M., Wang, Y., Rodeghero, R. I., Mikecz, K., Glant T. T., Iwakura, Y., and Finnegan, A.
    • Journal Title

      J. Immunol.

      Volume: 184 Pages: 1552-1559

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Host-derived Interleukin-1a is important in determining the immunogenicity of 3-Methylcholantrene-tumor cells.2009

    • Author(s)
      Elkabets, M., Krelin, Y., Dotan, S., Cerwenka, A., Porgador, A., Lichtenstein, R.G., White, M.R., Zoller, M., Iwakura, Y., Dinarello, C.A., Voronov, E., Apte, R.N.
    • Journal Title

      J. Immunol. 182

      Pages: 4874-4881

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-1 deficiency in combination with macrophage depletion increases susceptibility to Pseudomonas aeruginosa bacteremia.2009

    • Author(s)
      Horino, T., Matsumoto, T., Ishikawa, H., Kimura, S., Uramatsu, M., Tanabe, M., Tateda, K., Miyazaki, S., Aramaki, Y., Iwakura, Y., Yoshida, M., Onodera, S., Yamaguchi, K.
    • Journal Title

      Microbiol. Immunol. 53

      Pages: 502-511

    • NAID

      10027687393

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Characterization of mice deficient in Melanocortin 2 receptor on a B6/Balbc mix background2009

    • Author(s)
      Chida, D., Sato, T., Sato, Y., Kubo, M., Yoda, T., Suzuki, H., and Iwakura, Y.
    • Journal Title

      Mol. Cell. Endocrinol.

      Volume: 300 Pages: 32-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Role of T cell TGFβ signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection2009

    • Author(s)
      Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
    • Journal Title

      J.Immunol. 183

      Pages: 7297-7306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17 is involved in bone resorption in mouse periapical lesions.2009

    • Author(s)
      Oseko, F., Yamamoto, T., Akamatsu, Y., Kanamura, N., Iwakura, Y., Imanishi, J., Kita, M.
    • Journal Title

      Microbiol. Immunol. 53

      Pages: 287-294

    • NAID

      10027686578

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Pivotal role of cerebral interleukin-17-producingγδT cells in the delayed phase of ischemic brain injury2009

    • Author(s)
      Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D. J., Iwakura, Y., and Yoshimura, A.
    • Journal Title

      Nat. Med.

      Volume: 15 Pages: 946-950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Interleukin(IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-172009

    • Author(s)
      Munoz, M., Heimesaat, M. M., Danker, K., Struck, D., Lohmann, U., Plickert, R., Bereswill, S., Fischer, A., Dunay, I. R., Wolk, K., Loddenkemper, C., Krell, H.-W., Libert, C., Lund, L. R., Frey, O., Holscher, C., Iwakura, Y., Ghilardi, N., Ouyang, W., Kamradt, T., Sabat, R., and Liesenfeld, O.
    • Journal Title

      J. Exp. Med.

      Volume: 206 Pages: 3047-3059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Pivotal role of cerebral interleukin-17-producing gdT cells in the delayed phase of ischemic brain injury.2009

    • Author(s)
      Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D.J., Iwakura, Y., Yoshimura, A.
    • Journal Title

      Nat. Med. 15

      Pages: 946-950

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice.2009

    • Author(s)
      Lopez Kostka, S., Dinges, S., Griewank, K., Iwakura, Y., Udey, M.C., Von Stebut, E.
    • Journal Title

      J. Immunol. 182

      Pages: 3039-3046

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Biotin status affects nickel allergy via regulation of IL-1b production in mice.2009

    • Author(s)
      Kuroishi, T., Kinbara, M., Sato, N., Tanaka, Y., Nagai, Y., Iwakura, Y., Endo, Y., Sugawara, S.
    • Journal Title

      J. Nutrition 139

      Pages: 1031-1036

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Toll-like receptor 9-dependent activation of myeloid dendritic cells by deoxynucleic acids from Candida albicans.2009

    • Author(s)
      Miyazato A, Nakamura K, Yamamoto N, Mora-Montes HM, Tanaka M, Abe Y, Tanno D, Inden K, Gang X, Ishii K, Takeda K, Akira S, Saijo S, Iwakura Y, Adachi Y, Ohno N, Mitsutake K, Gow NA, Kaku M, Kawakami K.
    • Journal Title

      Infect. Immun. 77

      Pages: 3056-3064

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Role of T cell TGFβsignaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection.2009

    • Author(s)
      Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
    • Journal Title

      J. Immunol. 183

      Pages: 7297-7306

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Role of T cell TGFβ signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection2009

    • Author(s)
      Faust, S.M., Lu, G., Marini, B.L., Zou, W., Gordon, D., Iwakura, Y., Laouar, Y., Bishop, D.K.
    • Journal Title

      J.Immunol. 183

      Pages: 7297-7306

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-21022016
  • [Journal Article] Therapeutic effects of interleukin-6 blockade in a murine model of polymyositis that does not require interleukin-17A.2009

    • Author(s)
      Okiyama, N., Sugihara, T., Iwakura, Y., Yokozeki, H., Miyasaka, N., Kohsaka, H.
    • Journal Title

      Arth. Rheum. 60

      Pages: 2505-2512

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] E. Pulmonary inflammation triggered by Ricin toxin requires macrophages and IL-1 signaling2009

    • Author(s)
      Lindauer, M. L., Wong, J., Iwakura, Y., and Magun, B.
    • Journal Title

      J. Immunol.

      Volume: 183 Pages: 1419-1426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Tyrosine kinase 2 plays critical roles in the pathogenic CD4 T cell responses for the development of experimental autoimmune encephalomyelitis.2009

    • Author(s)
      Oyamada, A., Ikebem H., Itsumi, M., Saiwai, H., Okada, S., Shimoda, K., Iwakura, Y., Nakayama, K.I., Iwamoto, Y., Yoshikai, Y., Yamada, H.
    • Journal Title

      J. Immunol. 183

      Pages: 7539-7546

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses2009

    • Author(s)
      Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., and Iwakura, Y
    • Journal Title

      Immunity

      Volume: 30 Pages: 108-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Natural occurring IL-17 producing T cells regulagte the initial phase of neutrophil mediated airway responses.2009

    • Author(s)
      Tanaka, S., Yoshimoto, T., Naka, T., Nakae, S., Iwakura, Y., Cua, D., Kubo, M.
    • Journal Title

      J. Immunol. 183

      Pages: 7523-7530

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Hepatic platelet accumulation in Fas-mediated hepatitis in mice.2009

    • Author(s)
      Ohtaki Y, Yamaguchi K, Yu Z, Kumamoto H, Shimauchi H, Iwakura Y, Sugawara S, Endo Y.
    • Journal Title

      Int. Immunopharmacol. 9

      Pages: 1071-1078

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft versus host disease.2009

    • Author(s)
      Yi, T., Chen, Y., Wang, L., Du, G., Huang, D., Zhao, D., Johnstone, H., Young, J., Todorov, I., Umetsu, D.T., Chen, L., Iwakura, Y., Kandeel, F., Forman, S., Zeng, D.
    • Journal Title

      Blood 114

      Pages: 3101-3112

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.2009

    • Author(s)
      Munoz, M., Heimesaat, M. M., Danker, K., Struck, D., Lohmann, U., Plickert, R.,Bereswill, S., Fischer, A., Dunay, I. R., Wolk, K., Loddenkemper, C., Krell, H. -W., Libert, C., Lund, L. R., Frey, O., Holscher, C., Iwakura, Y., Ghilardi, N., Ouyang, W., Kamradt, T., Sabat, R., Liesenfeld, O. Interleukin
    • Journal Title

      J. Exp. Med. 206

      Pages: 3047-3059

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Dok-7 activates the muscle receptor kinase MuSK and shapes synapse formation2009

    • Author(s)
      Inoue, A., Setoguchi, K., Matsubara, Y., Okada, K., Sato, N., Iwakura, Y., Higuchi, O., and Yamanashi, Y.
    • Journal Title

      Science Signaling

      Volume: 2 Pages: 7-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] IL-17 promotes progression of cutaneous leishmaniasis in susceptible mice2009

    • Author(s)
      Lopez Kostka, S., Dinges, S., Griewank, K., Iwakura, Y., Udey, M. C., and Von Stebut, E.
    • Journal Title

      J. Immunol.

      Volume: 182 Pages: 3039-3046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] A. A protective function for interleukin 17A in T cell-mediated intestinal inflammation2009

    • Author(s)
      O' Connor, W. Jr., Kamanaka, M., Booth, C. J., Town, T., Nakae, S., Iwakura, Y., Kolls, J. K., and Flavell, R.
    • Journal Title

      Nat. Immunol.

      Volume: 10 Pages: 603-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] A protective function for interleukin 17A in T cell-mediated intestinal inflammation.2009

    • Author(s)
      O'Connor, W. Jr., Kamanaka, M., Booth, C.J., Town, T., Nakae, S., Iwakura, Y., Kolls, J.K., Flavell, R.A.
    • Journal Title

      Nat. Immunol. 10

      Pages: 603-609

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] MHC-matched corneal allograft rejection in an IFN-g/IL-17-independent manner in C57BL/6 mice.2009

    • Author(s)
      Yamada, J., Hamuro, J., Fukushima, A., Ohteki, T., Terai, K., Iwakura, Y., Yagita, H., Kinoshita, S.
    • Journal Title

      Invest. Ophthalmol. Vis. Sci. 50

      Pages: 2139-2146

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] T helper type 17 immune response plays an indispensable role for development of iodine-induced autoimmune thyroiditis in nonobese diabetic-H2h4 mice.2009

    • Author(s)
      Horie, I., Abiru, N., Nagayama, Y., Kuriya, G., Saitoh, O., Ichikawa, T., Iwakura, Y., Eguchi, K.
    • Journal Title

      Endocrinology 150

      Pages: 5135-5142

    • NAID

      120006983712

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Muramyldipeptide augments the actions of lipopolysacchairde in mice by stimulating macrophages to produe pro-IL-1b and by down-regulation of suppressor of cytokine signaling 1 (SOCS1).2009

    • Author(s)
      Shikama, Y., Kuroishi, T., Nagai, Y., Iwakura, Y., Shimauchi, H., Takada, H., Sugawara, S., Endo, Y.
    • Journal Title

      Innate Immun. (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Pulmonary inflammation triggered by Ricin toxin requires macrophages and IL-1 signaling.2009

    • Author(s)
      Lindauer, M.L., Wong, J., Iwakura, Y., Magun, B.E.
    • Journal Title

      J. Immunol. 183

      Pages: 1419-1426

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] CXCL12 promotes CCR7-dependent naive T-cell trafficking to lymph nodes and Peyer's patches.2009

    • Author(s)
      Bai, Z.B., Hayasaka, H., Kobayashi, M., Li, W., Guo, Z., Jang, M. -H., Kondo, A., Choi, B., Iwakura, Y., Miyasaka, M.
    • Journal Title

      J. Immunol. 182

      Pages: 1287-1295

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Virus binding to a plasma membrane receptor triggers interleukin-1α-mediated proinflammatory macrophage response in vivo.2009

    • Author(s)
      Di Paolo, N.C., Miao, E.A., Iwakura, Y., Kaja, M-K., Aderem, A., Flavell, R.A., Papayannopoulou, T., Shayakhmetov, D.M.
    • Journal Title

      Immunity 31

      Pages: 110-121

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Fracisella tularensis.2009

    • Author(s)
      Lin, Y., Ritchea, S., Logar, A., Slight, S., Messmer, M., Rangel-Moreno, J., Guglani, L., Alcorn, J. F., Strawbridge, H., Park, S. M., Onishi, R., Nyugen, N., Walter, M. J., Pociask, D., Randall, T. D., Gaffen, S. L., Iwakura, Y., Kolls, J. K., Khader, S. A*.
    • Journal Title

      Immunity 31

      Pages: 799-810

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Differential roles of IL-17A and IL-17F in host defense against mucoepithelial bacterial infection and allergic responses.2009

    • Author(s)
      Ishigame, H., Kakuta, S., Nagai, T., Nambu, A., Komiyama, Y., Kadoki, M., Tanahashi, Y., Akitsu, A., Kotaki, H., Sudo, K., Nakae, S., Sasakawa, C., Iwakura, Y.
    • Journal Title

      Immunity 30

      Pages: 108-119

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] M. Virus binding to a plasma membrane receptor triggers interleukin-1α-mediated proinflammatory macrophage response in vivo2009

    • Author(s)
      Di Paolo, N. C., Miao, E. A., Iwakura, Y., Kaja, M-K., Aderem, A., Flavell, R. A., Papayannopoulou, T., and Shayakhmetov, D.
    • Journal Title

      Immunity

      Volume: 31 Pages: 110-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages.2008

    • Author(s)
      Ashino, T., Yamanaka, R., Yamamoto, M., Shimokawa, H., Sekikawa, K., Iwakura, Y., Shioda, S., Numazawa, S., Yoshida, T.
    • Journal Title

      Mol. Immunol. 45

      Pages: 2106-2115

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Immunol. Rev 226

      Pages: 57-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015015
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Immunol. Rev. 226

      Pages: 57-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041025
  • [Journal Article] Suppressive role of leukocyte cell-derived chemotaxin 2 in mouse anti-type II collagen antibody-induced arthritis.2008

    • Author(s)
      Okumura, A., Saito, T., Otani, I., Kojima, K., Yamada, Y., Ishida-Okawara, A., Nakazato, K., Asano, M., Kanayama, K., Iwakura, Y., Suzuki, K., Yamagoe, S.
    • Journal Title

      Arthritis Rheum. 58

      Pages: 413-421

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Human T-cell leukemia virus type I infects human lung epithelial cells and induces gene expression of cytokines, chemokines and cell adhesion molecules.2008

    • Author(s)
      Teruya, H., Tomita, M., Senba, M., Ishikawa, C., Tamayose, M., Miyazato, A., Yara, S., Tanaka, Y., Iwakura, Y., Fujita, J., Mori, N.
    • Journal Title

      Retrovirology 5

      Pages: 86-86

    • NAID

      120001374675

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction2008

    • Author(s)
      Ogura, H., Murakami, M., Okyuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., and Hirano, T.
    • Journal Title

      Immunity

      Volume: 29 Pages: 628-636

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] CD44 and Bak expression in IL-6 or TNF-a gene knockout mice after whole lung irradiation.2008

    • Author(s)
      Sakai, M., Iwakawa, M., Iwakura, Y., Ohta, T., Tsujii, H., Imai, T.
    • Journal Title

      J. Radiat. Res. 49

      Pages: 409-416

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-17 promotes autoimmunity by triggering a positive-feedback loop via interleukin-6 induction.2008

    • Author(s)
      Ogura H., Murakami, M., Okyuyama, Y., Tsuruoka, M., Kitabayashi, C., Kanamoto, M., Nishihara, M., Iwakura, Y., Hirano, T*.
    • Journal Title

      Immunity 29

      Pages: 628-636

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of Natural Killer T cells and IL-17.2008

    • Author(s)
      Pichavant, M., Goya, S., Meyer, E.H., Johnston, R.A., Kim, H.Y., Matangkasombut, P., Zhu, M., Iwakura, Y., Savage, P.B., DeKruyff, R.H., Shore, S.A., Umetsu, D.T.
    • Journal Title

      J. Exp. Med. 205

      Pages: 385-393

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Differential roles for IFN-g and IL-17 in experimental autoimmune uveoretinitis.2008

    • Author(s)
      Yoshimura, T., Sonoda, K., Miyazaki, Y., Iwakura, Y., Ishibashi, T., Yoshimura, A., Yoshida, H.
    • Journal Title

      Int. Immunol. 20

      Pages: 209-214

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defence against pathogens2008

    • Author(s)
      Iwakura Y
    • Journal Title

      Immunol Rev. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20240041
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008

    • Author(s)
      Iwakura, Y., Nakae, S., Saijo, S., and Ishigame, H.
    • Journal Title

      Immunological Rev.

      Volume: 226 Pages: 57-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.2008

    • Author(s)
      Luger, D., Silver, P.B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E.P., Sgambellone, N.M., Chan, C. -C., Caspi, R.R.
    • Journal Title

      J. Exp. Med. 205

      Pages: 799-810

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Either a Th17 or a Th1 effector response can drive autoimmunity : conditions of disease induction affect dominant effector category2008

    • Author(s)
      Luger, D., Silver, P. B., Tang, J., Cua, D., Chen, Z., Iwakura, Y., Bowman, E. P., Sgambellone, N. M., Chan, C.-C. and Caspi, R.
    • Journal Title

      J. Exp. Med.

      Volume: 205 Pages: 799-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Increased fat-to-carbohydrate oxidation ratio in Il1ra^<-/-> mice on a high fat diet is associated with increased sympathetic tone2008

    • Author(s)
      Chida, D., Hashimoto, O., Kuwahara, M., Sagara, H., Osaka, T., Tsubone, H., and Iwakura, Y.
    • Journal Title

      Diabetologia

      Volume: 51 Pages: 1698-1706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis.2008

    • Author(s)
      Izcue, A., Hue, S., Buonocore, S., Arancibia-Carcamo, C.V., Ahern, P.P., Iwakura, Y., Maloy, K.J., Powrie, F
    • Journal Title

      Immunity 28

      Pages: 559-570

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IFN-γexpression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death.2008

    • Author(s)
      Atsumi, T., Sato, M., Kamimura, D., Moroi, A., Iwakura, Y., Betz, U.A., Yoshimura, A., Nishihara, M., Hirano, T., Murakami, M.
    • Journal Title

      Int. Immunol. 21

      Pages: 73-80

    • NAID

      10025383990

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis.2008

    • Author(s)
      Fukushima, A., Sumi, T., Ishida, W., Yamada, J., Iwakura, Y., Ueno, H.
    • Journal Title

      Int. Arch. Allergy Imm. 147

      Pages: 206-212

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Deficiency of tumor necrosis factor-a and interferon-g in bone marrow cells synergistically inhibits neointimal formation following vascular injury.2008

    • Author(s)
      Murayama, H., Takahashi, M., Takamoto, M., Shiba, Y., Ise, H., Koyama, J., Tagawa, Y., Iwakura, Y., Ikeda, U.
    • Journal Title

      Cardiovascular Res. 80

      Pages: 175-180

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia.2008

    • Author(s)
      Aujla, S.J., Fei, M., Pociask, D.A., Reinhart, T.A., Edeal, J., Gaus, K., Kreindler, J.L., Dubin, P.J., Zheng, M., Pilewski, J.M., Myerburg, M.M., Mason, C.A., Iwakura, Y., Kolls, J.K.
    • Journal Title

      Nature Med. 14

      Pages: 275-281

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell lines.2008

    • Author(s)
      Lees, J.R., Iwakura, Y., Russell, J.H.
    • Journal Title

      J. Immunol. 180

      Pages: 8066-8072

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-1 regulates the Cyp7a1 gene and serum total cholesterol level at steady state in mice.2008

    • Author(s)
      Kojima, M., Ashino, T., Yoshida, T., Iwakura, Y., Sekimoto, M., Degawa, M.
    • Journal Title

      Biochem. Biophys. Res. Commun. 379

      Pages: 239-242

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis2008

    • Author(s)
      Izcue, A., Hue, S., Buonocore, S., Arancibia-Carcamo, C. V., Ahern, P. P., Iwakura, Y., Maloy, K. J., and Powrie, F
    • Journal Title

      Immunity

      Volume: 28 Pages: 559-570

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice.2008

    • Author(s)
      Ito, R., Kita, M., Shin-Ya, M., Kishida, T., Urano, A., Takada, R., Sakagami, J., Imanishi, J., Iwakura, Y., Okanoue, T., Yoshikawa, T., Kataoka, K., Mazda, O.
    • Journal Title

      Biochem. Biophys. Res. Commun. 377

      Pages: 12-16

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Critical role for mesothelial cells in necrosis-induced inflammation through the recognition of IL-1a released from dying cells.2008

    • Author(s)
      Eigenbrod, T., Park, J-H., Harder, J., Iwakura, Y., Nunez, G.
    • Journal Title

      J. Immunol. 181

      Pages: 8194-8198

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The role of DCIR in the development of autoimmune diseases2008

    • Author(s)
      Fujikado, N., Saijo, S., Yonezawa, T., Shimamori, K., Ishii, A., Sugai, S., Kotaki, H., Sudo, K., Nose, M., and Iwakura, Y.
    • Journal Title

      Cytokine

      Volume: 43 Pages: 244-244

    • NAID

      40017145116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] CCL2 recruitment of IL-6 producing CD11b+ monocytes to the draining lymph nodes during the initiation of TH17-dependent B cellmediated autoimmunity.2008

    • Author(s)
      Bai, Y, Liu, R., Huang, D., La Cava, A., Tang, Y., Iwakura, Y., Campagnolo, D.I., Vollmer, T.L., Ransohoff, R.M., Shi, F.
    • Journal Title

      Eur. J. Immunol. 38

      Pages: 1877-1888

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-23 and Th17 cells enhance Th2 cell-mediated eosinophilic airway inflammation in mice.2008

    • Author(s)
      Wakashin, H., Hirose, K., Maezawa, Y., Kagami, S., Suto, A., Watanabe, N., Saito, Y., Hatano, M., Tokuhisa, T., Iwakura, Y., Puccetti, P., Iwamoto, I., Nakajima, H.
    • Journal Title

      Am. J. Respir. Crit. Care Med. 178

      Pages: 1023-1032

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Toll-like receptor 2 (TLR2) and dectin-1 contribute to the production of IL-12p40 by bone marrow-derived dendritic cells infected with Penicillium marneffei.2008

    • Author(s)
      Nakamura, K., Miyazato, A., Koguchi, Y., Adachi, Y., Ohno, N., Saijo, S., Iwakura, Y., Takeda, K., Akira, S., Fujita, J., Ishii, K., Kaku, M., Kawakami, K.
    • Journal Title

      Microbes Infect. 10

      Pages: 1223-1227

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Development of proteogylcan-induced arthritis is independent of IL-17.2008

    • Author(s)
      Doodes, P.D., Cao, Y., Hamel, K., Wang, Y., Hutas, G., Iwakura, Y., Finnegan, A.
    • Journal Title

      J. Immunol. 181

      Pages: 329-337

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Deoxynucleic acids from Cryptococcus neoformans activate myeloid dendritic cells via a TLR9-dependent pathway.2008

    • Author(s)
      Nakamura, K., Miyazato, A., Gang, X., Hatta, M., Inden, K., Aoyagi, T., Takeda, K., Akira, S., Saijo, S., Iwakura, Y., Adachi, Y., Ohno, N., Suzuki, K., Fujita, J., Kaku, M., Kawakami, K.
    • Journal Title

      J. Immunol. 180

      Pages: 4067-4074

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens.2008

    • Author(s)
      iwakura, Y.
    • Journal Title

      Immunol. Rev., 226

      Pages: 57-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Contribution of IL-1 to resistance to Streptococcus pneumoniae infection2008

    • Author(s)
      Kafka, D., Ling, E., Feldman, G., Benharroch, D., Voronov, E., Givon-Laci, N., Iwakura, Y., Dagan, R., Apte, R. N., and Mizrachi-Nebenzahi, Y.
    • Journal Title

      Int. Immunol.

      Volume: 9 Pages: 1139-1146

    • NAID

      10022599302

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Dcir deficiency causes development of autoimmune diseases in mice due to excess expansion of dendritic cells.2008

    • Author(s)
      Fujikado, N., Saijo, S., Yonezawa, T., Shimamori, K., Ishii, A., Sugai, S., Kotaki, H., Sudo, K., Nose, M., Iwakura, Y.
    • Journal Title

      Nat. Med. 14

      Pages: 176-180

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] L-17A produced by gammadelta T cells plays a critical role in innate immunity against Listeria monocytogenes infection in the liver.2008

    • Author(s)
      Hamada, S., Umemura, M., Shiono, T., Tanaka, K., Yahagi, A., Begum, M.D., Oshiro, K., Okamoto, Y., Watanabe, H., Kawakami, K., Roark, C., Born, W.K., O'Brien, R., Ikuta, K., Ishikawa, H., Nakae, S., Iwakura, Y., Ohta, T., Matsuzaki, G.
    • Journal Title

      J. Immunol. 181

      Pages: 3456-3463

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens.2008

    • Author(s)
      Iwakura, Y., Nakae, S., Saijo, S., Ishigame, H.
    • Journal Title

      Immunological Rev. 226

      Pages: 57-79

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Interleukin-1b and macrophage migration inhibitory factor (MIF) in dermal fibroblasts mediate UVA induced matrix metalloproteinase-1 expression.2008

    • Author(s)
      Honda, A., Abe, R., Makino, T., Norisugi, O., Fujita, Y., Watanabe, H., Nishihira, J., Yamagishi, S., Iwakura, Y., Shimizu, H., Shimizu, T.
    • Journal Title

      J. Dermatol. Sci. 49

      Pages: 63-72

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] L-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells2008

    • Author(s)
      Tajima, M., Wakita, D., Noguchi, D., Chamoto, K., Yue, Z, Fugo, K., Ishigame, H., Iwakura, Y., Kitamura, H., Nishimura, T.
    • Journal Title

      J. Exp. Med. 205

      Pages: 1019-1027

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17A is produced by Th17 cells, γδ T cells and other CD4- lymphocytes during infection with Salmonella enterica serovar Enteritidis and has a mild effect in bacterial clearance.2008

    • Author(s)
      Schulz, S.M., Kohler, G., Holscher, C., Iwakura, Y., Alber, G*.
    • Journal Title

      Int. Immunol. 9

      Pages: 1129-1138

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] K. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia2008

    • Author(s)
      Aujla, S. J., Fei, M., Pociask, D. A., Reinhart, T. A., Edeal, J., Gaus, K., Kreindler, J. L., Dubin, P. J., Zheng, M., Pilewski, J. M., Myerburg, M. M., Mason, C. A., Iwakura, Y., and Kolls, J.
    • Journal Title

      Nature Med.

      Volume: 14 Pages: 275-281

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of Natural Killer T cells and IL-172008

    • Author(s)
      Pichavant, M., Goya, S., Meyer, E. H., Johnston, R. A., Kim, H. Y., Matangkasombut, P., Zhu, M., Iwakura, Y., Savage, P. B., DeKruyff, R. H., Shore, S. A., and Umetsu, D. T.
    • Journal Title

      J. Exp. Med.

      Volume: 205 Pages: 385-393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Protective immunity to systemic infection with Salmonella enterica serovar Enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22 but not IL-17.2008

    • Author(s)
      Schulz, S.M., Kohler, G., Schutze, N., Knauer, J., Straubinger, R.K., Chackerian, A.A., Witte, E., Wolk, K., Sabat, R., Iwakura, Y., Holscher, C., Muller, U., Kastelein, R.A., Alber, G.
    • Journal Title

      J. Immunol. 181

      Pages: 7891-7901

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17 contributes to CD4-mediated graft-versus-host disease.2008

    • Author(s)
      Kappel, L.W., Goldberg, G.L., King, C.G., Suh, D., Smith, O.M., Ligh, C., Holland, A., Grubin, J., Liu, C., Iwakura, Y., Mark, N., Heller, G., van den Brink, M.R.M.
    • Journal Title

      Blood 113

      Pages: 628-636

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Contribution of IL-1 to resistance to Streptococcus pneumoniae infection.2008

    • Author(s)
      Kafka, D., Ling, E., Feldman, G., Benharroch, D., Voronov, E., Givon-Laci, N., Iwakura, Y., Dagan, R., Apte, R.N., Mizrachi-Nebenzahi, Y.
    • Journal Title

      Int. Immunol. 9

      Pages: 1139-1146

    • NAID

      10022599302

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The mechanisms of the stress-induced behavioral abnormality in the IL-1 receptor antagonist(IL-1Ra) KO mice2008

    • Author(s)
      Wakabayashi, C., and Iwakura, Y.
    • Journal Title

      Neuroscience Res.

      Volume: 61 Pages: 63-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] The roles of IL-17A in inflammatory immune responses and host defense against pathogens2008

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Immanol. Rev. 226

      Pages: 57-79

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] L-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8^+T cells2008

    • Author(s)
      Tajima, M., Wakita, D., Noguchi, D., Chamoto, K., Yue, Z, Fugo, K., Ishigame, H., Iwakura, Y., Kitamura, H., and Nishimura, T
    • Journal Title

      J. Exp. Med.

      Volume: 205 Pages: 1019-1027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Journal Article] Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice.2007

    • Author(s)
      Kagari, T., Tanaka, D., Doi, H., Iwakura, Y., Shimozato, T.
    • Journal Title

      Eur. J. Immunol. 37

      Pages: 2753-2763

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Alteration of behavioural phenotype in mice by targeted disruption of the progranulin gene.2007

    • Author(s)
      Kayasuga, Y., Chiba, S., Suzuki, M., Kikusui, T., Matsuwaki, T., Yamanouchi, K., Kotaki, H., Horai, R., Iwakura, Y., Nishihara, M.
    • Journal Title

      Behav. Brain Res. 185

      Pages: 110-118

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17と新規Il-17産生ヘルパーT細胞サブセット2007

    • Author(s)
      岩倉 洋一郎
    • Journal Title

      感染・炎症・免疫 (印刷中)

    • Data Source
      KAKENHI-PROJECT-18060010
  • [Journal Article] IL-17と新規I1-17産生ヘルパーT細胞サブセット2007

    • Author(s)
      岩倉 洋一郎
    • Journal Title

      感染・炎症・免疫 (印刷中)

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Inflammasome-mediated production of IL-1b is required for neutrophil recruitment against Staphylococcus aureus in vivo.2007

    • Author(s)
      Miller, L.S., Pietras, E.M., Uricchio, L.H., Hirano, K., Rao, S., Lin, H., O'Connell, R.M., Iwakura, Y., Cheung, A.L., Cheng, G., Modlin, R.L.
    • Journal Title

      J. Immunol. 179

      Pages: 6933-6942

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Knockout mice lacking cPGES/p23, a constitutively expressed PGE(2) synthetic enzyme, are peri-natally lethal.2007

    • Author(s)
      Nakatani, Y., Hokonohara, Y., Kakuta, S., Sudo, K., Iwakura, Y., Kudo, I.
    • Journal Title

      Biochem. Biophys. Res. Commun. 362

      Pages: 387-92

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Involvement of protein-tyrosine phosphatase PTPMEG in motor learning and cerebellar long-term depression.2007

    • Author(s)
      Kina, S., Tezuka, T., Kusakawa, S., Kishimoto, Y., Kakizawa, S., Hashimoto, K., Ohsugi, M., Kiyama, Y., Horai, R., Sudo, K., Kakuta, S., Iwakura, Y., Iino, M., Kano, M., Manabe, T., Yamamoto, T.
    • Journal Title

      Eur. J. Neurosci. 26

      Pages: 2269-2278

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Melanocortin receptor 2 is required for adrenal gland development, steroidogenesis and neonatal gluconeogenesis.2007

    • Author(s)
      Chida, D., Nakagawa, S., Nagai, S., Sagara, H., Katsumata, H., Imaki, T., Suzuki, H., Mitani, F., Ogishima, T., Shimizu, C., Kotaki, H., Kakuta, S., Sudo, K., Koike, T., Kubo, M., Iwakura, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 104

      Pages: 18205-18210

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] IL-17と新規I1-17産生ヘルパーT細胞サブセット2007

    • Author(s)
      岩倉 洋一郎
    • Journal Title

      感染・炎症・免疫 (印刷中)

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a Th17-independent manner.2007

    • Author(s)
      Noguchi, D., Wakita, D., Tajima, M., Ashino, S., Iwakura, Y., Zhang, Y., Chamoto, K., Kitamura, H., Nishimura, T.
    • Journal Title

      Int. Immunol. 19

      Pages: 1431-1440

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] Differential role and tissue specificity of interleukin-1alpha gene expression in atherogenesis and lipid metabolism.2007

    • Author(s)
      Kamari, Y., Werman-Venkert, R., Shaish, A., Werman, A., Harari, A., Gonen, A., Voronov, E., Grosskopf, I., Sharabi, Y., Grossman, E., Iwakura, Y., Dinarello, C.A., Apte, R.N., Harats, D.
    • Journal Title

      Atherosclerosis 195

      Pages: 31-38

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The IL-23/IL-17 axis in inflammation.2006

    • Author(s)
      Iwakura Y.
    • Journal Title

      J. Clin Invest 116

      Pages: 1218-1222

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] The IL-23/IL-17 axis in inflammation.2006

    • Author(s)
      Iwakura, Y.
    • Journal Title

      J. Clin. Invest. 116(5)

      Pages: 1218-1222

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] Combined IL-6 and IL-1 deficiency causes obesity in young mice.2006

    • Author(s)
      Chida, D., Osaka, T., Hashimoto, O., Iwakura, Y.
    • Journal Title

      Diabetes 55

      Pages: 971-977

    • Data Source
      KAKENHI-PROJECT-16046207
  • [Journal Article] The IL-23/IL-17 axis in inflammation2006

    • Author(s)
      Iwakura Y.
    • Journal Title

      J Clin Invest 116

      Pages: 1218-1222

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006

    • Author(s)
      Ishigame, H., Nakajima, A., Saijo, S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura, Y.
    • Journal Title

      Ernst Schering Res Found Workshop.: 56

      Pages: 129-153

    • Data Source
      KAKENHI-PROJECT-17500284
  • [Journal Article] The IL-23/IL-17 axis in inflammation.2006

    • Author(s)
      Iwakura, Y.
    • Journal Title

      J. Clin. Invest. 116(5)

      Pages: 1218-22

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.2006

    • Author(s)
      Matsuki I., Nakae, S., Sudo, K., Horai, R., Iwakura, Y.
    • Journal Title

      Int.Immunol., 18

      Pages: 399-340

    • NAID

      10020621858

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice2006

    • Author(s)
      Kotani, M., Hirata, K., Ogawa, S., Habiro, K.Ishida, Y., Tanuma, S., Horai R., Iwakura, Y., Kishimoto, H., Abe, R
    • Journal Title

      Arthritis Rheum. 53

      Pages: 473-481

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006

    • Author(s)
      Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura.Y
    • Journal Title

      Ernst Schering Res Found Workshop. 56

      Pages: 129-153

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Abnormal T cell activation caused by the imbalance of the IL-1/IL-1R antagonist system is responsible for the development of experimental autoimmune encephalomyelitis.2006

    • Author(s)
      Matsuki, T., Nakae S., Sudo, K., Horai, R., Iwakura, Y.
    • Journal Title

      Int.Immunol., 18

      Pages: 399-340

    • NAID

      10020621858

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] The role of TNF a and IL-17 in the development of excess IL-1 signaling-induced inflammatory diseases in IL-1 receptor antagonist-deficient mice.2006

    • Author(s)
      Ishigame, H., Nakajima, A., Saijo S., Komiyama, Y., Nambu, A., Matsuki, T., Nakae, S., Horai, R., Kakuta, S., Iwakura, Y
    • Journal Title

      Ernst Schering Res Found Workshop. 56

      Pages: 129-153

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] CD28-dependent differentiation into the effector/memory phenotype is essential for induction of arthritis in interleukin-1 receptor antagonist-deficient mice2006

    • Author(s)
      Kotani, M., Hirata, K., Ogawa, S., Habiro K., Ishida, Y., Tanuma, S., Horai R., Iwakura, Y., Kishimoto, H., Abe R
    • Journal Title

      Arthritis Rheum. 53

      Pages: 473-481

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] The IL-23/IL-17 axis in inflammation.2006

    • Author(s)
      Iwakura, Y.
    • Journal Title

      J. Clin. Invest. 116(5)

      Pages: 1218-1222

    • Data Source
      KAKENHI-PROJECT-18060010
  • [Journal Article] Involvement of tumor necrosis factor-alpha in the development of T cell-dependent aortitis in interleukin-1 receptor antagonist-deficient mice.2005

    • Author(s)
      Matsuki, I., Isoda, K., Horai, R., Nakajima, A., Aizawa Y., Suzuki, K., Ohsuzu, F., Iwakura, Y.
    • Journal Title

      Circulation 30

      Pages: 1323-1331

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Involvement of corticotropin-releasing hormone-and interleukin-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1α.2005

    • Author(s)
      Chida, D., Imaki I., Suda, I., Iwakura, Y
    • Journal Title

      Endocrinology,: 146

      Pages: 5496-5502

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Deficiency of interleukin-1 receptor antagonist deteriorates fatty-liver and cholesterol metabolism in hypercholesterolemic mice.2005

    • Author(s)
      Isoda K, Sawada S, Ayaori M, Matsuki T, Horai R, Kagata Y, Miyazaki K, Kusuhara M, Okazaki M, Matsubara O, Iwakura Y, Ohsuzu F.
    • Journal Title

      J Biol Chem. 280・8

      Pages: 7002-7009

    • Data Source
      KAKENHI-PROJECT-16046207
  • [Journal Article] Involvement of tumor necrosis factor-alpha in the development of T cell-dependent aortitis in interleukin-1 receptor antagonist-deficient mice.2005

    • Author(s)
      Matsuki, T., Isoda, K., Horai, R., Nakajima A., Aizawa Y., Suzuki, K., Ohsuzu, F., Iwakura, Y.
    • Journal Title

      Circulation 30

      Pages: 1323-1331

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] Involvement of CRH-and IL-6-dependent proopiomelanocortin induction in the anterior pituitary during hypothalamic-pituitary-adrenal axis activation by IL-Ia.2005

    • Author(s)
      Chida, D., Imaki, T., Suda, T., Iwakura, Y.
    • Journal Title

      Endocrinology 146

      Pages: 5496-5502

    • Data Source
      KAKENHI-PROJECT-16046207
  • [Journal Article] Involvement of corticotropin-releasing hormone-and interleukin-6-dependent proopiomelanocortin induction in the anterior Pituitary during hypothalamic-pituitary-adrenal axis activation by IL-1α.2005

    • Author(s)
      Chida, D., Imaki, T., Suda, T., Iwakura Y
    • Journal Title

      Endocrinology,: 146

      Pages: 5496-5502

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] Arthritis In mice that are deficient in interlelukin-1 receptor antagonist is dependent on genetic background.2005

    • Author(s)
      Zho, F., He, X., Iwakura, Y., Horai, R., Stuart, JM
    • Journal Title

      Arthritis Rheum. 52

      Pages: 3731-3738

    • Data Source
      KAKENHI-PROJECT-17047011
  • [Journal Article] Arthritis in mice that are deficient in interleukin-1 receptor antagonist is dependent on genetic background.2005

    • Author(s)
      Zho, F., He, X., Iwakura, Y., Horai, R., Stuart JM
    • Journal Title

      Arthritis Rheum. 52

      Pages: 3731-3738

    • Data Source
      KAKENHI-PROJECT-17390140
  • [Journal Article] Induction of IgG2a class switching in B cells by IL-272004

    • Author(s)
      Yoshimoto, T., Iwakura, Y., Mizuguchi, J et al.
    • Journal Title

      J.Immunol 173

      Pages: 2479-2485

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004

    • Author(s)
      Kudo M., Aosai F., Mun H-s., Norose K., Shizuo A., Iwakura Y., Yano A.
    • Journal Title

      Microbiol.Immunol. 48

      Pages: 617-628

    • NAID

      10013440531

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004

    • Author(s)
      Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M.Mohamed, Piao L-X, Iwakura Y, Yano A
    • Journal Title

      Microbiol.Immunol. 48(3)

      Pages: 185-193

    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] Interleukin (IL)-6, but not IL-1, induction in the brain downstream of cyclooxygenase-2 is essential for the induction of febrile response against peripheral IL-1 alpha.2004

    • Author(s)
      Kagiwada K, Chida D, Sakatani T, Asano M, Nambu A, Kakuta S, Iwakura Y.
    • Journal Title

      Endocrinology 145・11

      Pages: 5044-5048

    • Data Source
      KAKENHI-PROJECT-16046207
  • [Journal Article] Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice.2004

    • Author(s)
      Hata, H., Sakaguchi, N., Iwakura, Y., Sakaguchi, S et al.
    • Journal Title

      J.Clin.Invest 114

      Pages: 582-588

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Induction of IgG2a class switching in B cells by IL-272004

    • Author(s)
      Yoshimoto, T., Iwakura, Y., Mizuguchi, J et al.
    • Journal Title

      J.Immunol 173

      Pages: 2479-2485

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Involvement of IL-17 in Fas ligand-induced inflammation2004

    • Author(s)
      Umemura, M., Iwakura, Y., Suda, T.et al.
    • Journal Title

      Int Immunol 16

      Pages: 1099-1108

    • NAID

      10013425139

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004

    • Author(s)
      Yasuda, T., Shirakata, M., Iwakura, Y., Yamanashi, Y et al.
    • Journal Title

      J.Exp.Med 200

      Pages: 1681-1687

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis2004

    • Author(s)
      Ishihara, K., Sawa, S.Iwakura, Y., Hirano, T et al.
    • Journal Title

      Int.Immunol 16

      Pages: 455-465

    • NAID

      10013084315

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] TNFα is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2004

    • Author(s)
      Horai, R., Saijo, S., Iwakura, Y.et al.
    • Journal Title

      J.Clin.Invest 114

      Pages: 1603-1611

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation2004

    • Author(s)
      Park, S.J., Iwakura, Y., Ishihara.K, M., Hirano, T.et al.
    • Journal Title

      J.Immunol 173

      Pages: 3844-3854

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004

    • Author(s)
      Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M Mohamed, Piao L-X, Iwakura Y, Yano A
    • Journal Title

      Microbiol.Immunol. 48(3)

      Pages: 185-193

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] IL-6, but not IL-1, induction in the brain downstream of Cox-2 is essential for the induction of febrile response against peripheral IL-1α.2004

    • Author(s)
      Kagiwada, K., Chida, D., Iwakura, Y
    • Journal Title

      Endocrinology 145

      Pages: 5044-5048

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] Evaluation of the effect of sulfamethoxazole on Toxoplasma gondii loads and stage conversion in IFN-g knockout mice using QC-PCR2004

    • Author(s)
      Usama S.Belal, Norose K, Aosai F, Mun H-S, Azza K.Ahmed, Chen M, Rabie M.Mohamed, Piao L-X, Iwakura Y, Yano A.
    • Journal Title

      Microbiol.Immunol. 48(3)

      Pages: 185-193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] TNFα is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2004

    • Author(s)
      Horai, R., Saijo, S., Iwakura, Y.et al.
    • Journal Title

      J.Clin.Invest 114

      Pages: 1603-1611

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation2004

    • Author(s)
      Park S.J., Iwakura, Y., Ishihara, K., M., Hirano, T.et al.
    • Journal Title

      J.Immunol 173

      Pages: 3844-3854

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] IL-6, but not IL-1, induction in the brain downstream of Cox-2 is essential for the induction of febrile response against peripheral IL-1α.2004

    • Author(s)
      Kagiwada, K., Chida, D., Iwakura, Y
    • Journal Title

      Endocrinology 145

      Pages: 5044-5048

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Role of Dok-1 and Dok-2 in myeloid homeostasis and suppression of leukemia.2004

    • Author(s)
      Yasuda, T., Shirakata, M., Iwakura, Y., Yamanashi, Y et al.
    • Journal Title

      J.Exp.Med 200

      Pages: 1681-1687

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Involvement of IL-17 in Fas ligand-induced inflammation2004

    • Author(s)
      Umemura, M., Iwakura, Y., Suda, T.et al.
    • Journal Title

      Int Immunol 16

      Pages: 1099-1108

    • NAID

      10013425139

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004

    • Author(s)
      Kudo M., Aosai R, Mun H-S., Norose K., Shizuo A., Iwakura Y., Yano A.
    • Journal Title

      Microbiol.Immunol. 48

      Pages: 617-628

    • NAID

      10013440531

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] The point mutation of tyrosine 759 of the IL-6 family cytokine receptor gp130 synergizes with HTLV-1 pX in promoting rheumatoid arthritis-like arthritis2004

    • Author(s)
      Ishihara, K., Sawa, S.Iwakura, Y., Hirano, T et al.
    • Journal Title

      Int Immunol 16

      Pages: 455-465

    • NAID

      10013084315

    • Data Source
      KAKENHI-PROJECT-16012209
  • [Journal Article] Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice.2004

    • Author(s)
      Hata, H., Sakaguchi, N., Iwakura, Y., Sakaguchi, S et al.
    • Journal Title

      J.Clin.Invest 114

      Pages: 582-588

    • Data Source
      KAKENHI-PROJECT-16043216
  • [Journal Article] The role of IFN-γ and toll-like receptors in nephropathy induced by Toxoplasma gondii infection.2004

    • Author(s)
      Kudo M., Aosai F., Mun H-S., Norose K., Shizuo A., Iwakura Y., Yano A.
    • Journal Title

      Microbiol.Immunol. 48

      Pages: 617-628

    • NAID

      10013440531

    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] Autoimmune chronic inflammatory arthropathy in mice transgenic for the HTLV-I tax gene.2003

    • Author(s)
      Iwakura, Y.
    • Journal Title

      Gann Monograph on Cancer Res. 50

      Pages: 95-109

    • NAID

      50000788513

    • Data Source
      KAKENHI-PROJECT-15039206
  • [Journal Article] 炎症、アレルギー病態におけるIL-17の役割2003

    • Author(s)
      岩倉洋一郎
    • Journal Title

      Molecular Medicine(臨時増刊号)免疫2004 40

      Pages: 252-258

    • Data Source
      KAKENHI-PROJECT-15039206
  • [Journal Article] Pathogenecity of toxoplasma gondii through B-2 cell-mediated downregulation of host defense responses.2003

    • Author(s)
      HYe-Seong Mun, Fumie Aosai, Mei Chen, Lian-Xun Piao, Kazumi Norose, Yoichiro Iwakura, Akihiko Yano
    • Journal Title

      Invest.Opthalmol.Vis.Sci. 44

      Pages: 4375-4381

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] Pathogenicity of Toxoplasma gondii through B-2 cell-mediated downreguiation of host defense responses.2003

    • Author(s)
      Hye-Seong Mun, Fumie Aosai, Mei Chen, Lian-Xun Piao, Kazumi Norose, Yoichiro Iwakura, Akihiko Yano
    • Journal Title

      Microbiol.Immunol. 47(7)

      Pages: 533-542

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390135
  • [Journal Article] Characterization of a variant virus from ascites of subacute granulomatous serositis in interferon-g-deficient C57BL/6 mice persistently infected with murine coronavirus strain JHM.

    • Author(s)
      Taguchi, F., Matsuyama, S., Iwakura, Y., Tagawa, Y., Saegusa, J., Kyuwa, S.
    • Journal Title

      Viral Immunol. (in press)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] TNF, but not IL-6 and IL-17, is crucial for the development of T cell-independent psoriasis-like dermatitis in Il1rn-/- mice.

    • Author(s)
      Nakajima, A., Matsuki, T., Komine, M., Asahina, A., Horai, R., Ishigame, H., Nakae, S., Kakuta, S., Saijo, S., Iwakura, Y.
    • Journal Title

      J. Immunol. (in press)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Journal Article] The mechanism of lipopolysaccharide-induced human immunodeficiency virus type I activation in transgenic mouse macrophages.

    • Author(s)
      Kadoki, M., Choi, B.I., Iwakura, Y.
    • Journal Title

      Int. Immunol. (in press)

    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] 腸管腫瘍抑制剤、PGE2産生抑制剤、及びIL-22BP産生促進剤2022

    • Inventor(s)
      岩倉洋一郎、唐策
    • Industrial Property Rights Holder
      岩倉洋一郎、唐策
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2021-204572
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-20H03176
  • [Patent] Method for the treatment of an autoimmune disease with an agent comprising CTRP32019

    • Inventor(s)
      Y. Iwakura, M. Murayama
    • Industrial Property Rights Holder
      Y. Iwakura, M. Murayama
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] Th17細胞誘導性疾患の予防又は治療剤、およびTh17細胞誘導性疾患の予防又は治療剤のスクリーニング法2019

    • Inventor(s)
      岩倉洋一郎、村山正承、小野貴裕、松岡眞子
    • Industrial Property Rights Holder
      岩倉洋一郎、村山正承、小野貴裕、松岡眞子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Patent] h17細胞誘導性疾患の予防又は治療剤、およびTh17細胞誘導性疾患の予防又は治療剤のスクリーニング法2019

    • Inventor(s)
      岩倉洋一郎、村山正承、小野貴裕、松岡眞子
    • Industrial Property Rights Holder
      岩倉洋一郎、村山正承、小野貴裕、松岡眞子
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-148054
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] 自己免疫疾患の治療薬および治療方法2019

    • Inventor(s)
      岩倉洋一郎、村山正承
    • Industrial Property Rights Holder
      岩倉洋一郎、村山正承
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2019
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] 自己免疫疾患の治療薬および治療方法2019

    • Inventor(s)
      岩倉洋一郎、村山正承
    • Industrial Property Rights Holder
      岩倉洋一郎、村山正承
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Acquisition Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Patent] 抗IL-17F中和抗体の炎症性腸疾患に対する治療・予防効果2018

    • Inventor(s)
      岩倉洋一郎、唐策
    • Industrial Property Rights Holder
      岩倉洋一郎、唐策
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Patent] 乳酸菌増殖促進剤、制御性T細胞T細胞増加剤、乳酸菌増殖促進方法、制御性T細胞を増加させる方法、制御性T細胞増加効果の評価方法、および乳酸菌増殖促進効果の評価方法2018

    • Inventor(s)
      岩倉洋一郎、唐策、大野尚仁
    • Industrial Property Rights Holder
      岩倉洋一郎、唐策、大野尚仁
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2018
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] 樹状細胞の成熟抑制剤及び成熟抑制方法、並びに医薬組成物2018

    • Inventor(s)
      岩倉洋一郎、矢部力朗
    • Industrial Property Rights Holder
      岩倉洋一郎、矢部力朗
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Patent] 樹状細胞の成熟抑制剤及び成熟抑制方法、並びに医薬組成物2018

    • Inventor(s)
      岩倉洋一郎、矢部力朗
    • Industrial Property Rights Holder
      岩倉洋一郎、矢部力朗
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] 抗IL-17F中和抗体の炎症性腸疾患に対する治療・予防効果2018

    • Inventor(s)
      岩倉洋一郎、唐策
    • Industrial Property Rights Holder
      岩倉洋一郎、唐策
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Patent] 乳酸菌増殖促進剤、制御性T細胞T細胞増加剤、乳酸菌増殖促進方法、制御性T細胞を増加させる方法、制御性T細胞増加効果の評価方法、および乳酸菌増殖促進効果の評価方法2018

    • Inventor(s)
      岩倉洋一郎、唐策、大野尚仁
    • Industrial Property Rights Holder
      岩倉洋一郎、唐策、大野尚仁
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Acquisition Date
      2018
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法。2014

    • Inventor(s)
      岩倉洋一郎、海部知則、矢部力朗
    • Industrial Property Rights Holder
      岩倉洋一郎、海部知則、矢部力朗
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-14
    • Overseas
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Patent] 樹状細胞免疫受容体活性化剤、樹状細胞免疫受容体活性化方法、破骨細胞形成抑制剤、破骨細胞形成抑制方法、樹状細胞分化・増殖阻害剤、樹状細胞分化・増殖阻害方法2014

    • Inventor(s)
      岩倉洋一郎、海部知則、矢部力朗
    • Industrial Property Rights Holder
      岩倉洋一郎、海部知則、矢部力朗
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-11
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Patent] CTRP3 plays an important role in the development of collagen-induced arthritis in mice.2013

    • Inventor(s)
      岩倉洋一郎,村山正承
    • Industrial Property Rights Holder
      東京理科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2013-11-15
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Patent] 自己免疫疾患治療及び予防薬としてのCTRP62012

    • Inventor(s)
      岩倉洋一郎,村山正承,石亀晴道,角田茂 (東京大学)
    • Industrial Property Rights Holder
      岩倉洋一郎,村山正承,石亀晴道,角田茂 (東京大学)
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-11-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Patent] 腸疾患の治療方法および治療用医薬組成物2011

    • Inventor(s)
      岩倉洋一郎、角田茂、鈴木俊佐
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-02-02
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] 樹状細胞免疫受容体刺激剤2011

    • Inventor(s)
      岩倉洋一郎、藤門範行、馬光宇
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2011-02-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] IL-17A/IL-17Fを介した大腸がん発症制御2010

    • Inventor(s)
      岩倉洋一郎、角田茂、鈴木俊佐
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2010-02-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20015015
  • [Patent] 骨免疫疾患の予防・治療剤2010

    • Inventor(s)
      岩倉洋一郎、藤門範行、馬光宇
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2010-02-23
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] 骨免疫疾患の予防・治療剤2010

    • Inventor(s)
      岩倉洋一郎、藤門範行、馬光宇
    • Industrial Property Rights Holder
      国立大学法人,東京大学, 他3名
    • Filing Date
      2010-02-23
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] 骨免疫疾患の予防・治療剤2010

    • Inventor(s)
      岩倉洋一郎、藤門範行、馬光宇
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2010-02-23
    • Acquisition Date
      2010-02-23
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] IL-17A/IL-17Fを介した大腸がん発症抑制2010

    • Inventor(s)
      岩倉洋一郎、角田茂、鈴木俊佐
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2010-02-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] IL-17A/IL-17Fを介した大腸がん発症抑制2010

    • Inventor(s)
      岩倉洋一郎、角田茂、鈴木俊佐
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2010-02-03
    • Acquisition Date
      2010-02-03
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] IL-1タイプIIレセプター遺伝子の欠損変異体マウス2009

    • Inventor(s)
      岩倉洋一郎、角田茂, 他4名
    • Industrial Property Rights Holder
      国立大学法人,東京大学, 他10名
    • Acquisition Date
      2009-08-20
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] IL-17A/IL-17F制御による感染症治療・予防薬Differential Roles of Interleukin-17A and Interleukin-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses2009

    • Inventor(s)
      岩倉洋一郎、角田茂、石亀晴道
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2009-12-28
    • Acquisition Date
      2009-12-28
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] IL-17A/IL-17F制御による感染症治療・予防薬、Differentail Roles of Interleukin-17A and Interleukin-17F in Host defense against Mucoepithelial Bacterial Infection and Allegic Responses2009

    • Inventor(s)
      岩倉洋一郎、角田茂、石亀晴道
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2009-12-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Patent] IL-1タイプIIレセプター遺伝子の欠損変異体マウス2009

    • Inventor(s)
      岩倉洋一郎、角田茂、棚橋侑子、宝来玲子、畦地里衣、中嶋明子
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2009-02-05
    • Acquisition Date
      2009-02-05
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] IL-17A/IL-17F制御によるアレルギーや細菌感染の治療法の開発Differential Roles of Interleukin-17A and Interleukin-17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses2008

    • Inventor(s)
      岩倉洋一郎、角田茂、石亀晴道
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Filing Date
      2008-12-30
    • Acquisition Date
      2008-12-30
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Patent] 樹状細胞免疫受容体遺伝子ノックアウト疾患モデル動物2007

    • Inventor(s)
      岩倉洋一郎
    • Industrial Property Rights Holder
      岩倉洋一郎
    • Filing Date
      2007-02-09
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] イミキモド誘導乾癬およびDSS誘導大腸炎発症における炎症性サイトカインIL-36alphaの機能解析2020

    • Author(s)
      矢部力朗、鄭琇絢、西城忍、岩倉洋一郎
    • Organizer
      第67回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-19K06465
  • [Presentation] 低分子βグルカンによる腸管免疫の制御2020

    • Author(s)
      岩倉洋一郎
    • Organizer
      βグルカン協議会セミナー ADEKA本社
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] 低分子βグルカンによる腸管免疫の制御2020

    • Author(s)
      岩倉洋一郎
    • Organizer
      βグルカン協議会セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] 低分子βグルカンによる腸管免疫の制御2020

    • Author(s)
      岩倉洋一郎
    • Organizer
      βグルカン協議会セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Roles of C-type lectins in the homeostasis of the intestinal immunity2019

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      NIH-Japan Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of CTRP6 in renal tubulointerstitial lesion progression.2019

    • Author(s)
      Hsi Hua Chi, Masanori A. Murayama and Yoichiro Iwakura
    • Organizer
      Innate immune receptors: Roles in immunology and beyond (M1), 2019 Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] The role of CTRP family members in the immune system.2019

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 30th Anniversary International Symposium of Research Institute for Biomedical Sciences, Tokyo University of Science
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] The role of CTRP6 in renal tubulointerstitial lesion progression.2019

    • Author(s)
      Hsi Hua Chi, Masanori A. Murayama and Yoichiro Iwakura
    • Organizer
      Innate immune receptors: Roles in immunology and beyond (M1), 2019 Keystone Symposia
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] 糖鎖修飾酵素の投与による免疫制御法の開発.2019

    • Author(s)
      鄭琇絢、岩倉洋一郎
    • Organizer
      第66回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] サイトカインIL-36alphaはイミキモド誘導乾癬様皮膚炎の発症に重要な役割を果たす2019

    • Author(s)
      矢部力朗、鄭琇絢、橋口裕里子、西城忍、岩倉洋一郎
    • Organizer
      第66回日本実験動物学会総会
    • Data Source
      KAKENHI-PROJECT-19K06465
  • [Presentation] 糖鎖修飾酵素の投与による免疫制御法の開発2019

    • Author(s)
      鄭琇絢、岩倉洋一郎
    • Organizer
      第66回日本実験動物学会総会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of CLR-X in colorectal tumorigenesis2019

    • Author(s)
      Xi Fu and Yoichiro Iwakura
    • Organizer
      第48回日本免疫学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Elucidating the role of CTRP6 in renal fibrosis and acute kidney failure.2019

    • Author(s)
      紀 熙華, 村山 正承, 岩倉 洋一郎
    • Organizer
      第84回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Suppression of IL-17F, but not IL-17A, provides protection against colitis by inducing Treg cell through modification of the intestinal microbiota2019

    • Author(s)
      Ce Tang, Shigeru Kakuta, and Yoichiro Iwakura
    • Organizer
      The 17th International Congress of Immunology (IUIS), Beijing, China
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Elucidating the role of CTRP6 in renal fibrosis and acute kidney failure2019

    • Author(s)
      Hsi Hua Chi, Masanori A. Murayama and Yoichiro Iwakura
    • Organizer
      第84回日本インターフェロン・サイトカイン学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] βグルカンの腸管免疫に及ぼす影響について2019

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本農芸化学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota2019

    • Author(s)
      Ce Tang, Shigeru Kakuta, and Yoichiro Iwakura
    • Organizer
      The 17th International Congress of Immunology (IUIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] βグルカンの腸管免疫に及ぼす影響について2019

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本農芸化学会2019年度大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] The role of CTRP family members in the immune system.2019

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 30th Anniversary International Symposium of Research Institute for Biomedical Sciences, Tokyo University of Science
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Attempt to decipher the role of CLR-x in intestinal tumorigenesis: insights from tumor-associated immune cells and gene expression2019

    • Author(s)
      Xi Fu and Yoichiro Iwakura
    • Organizer
      炎症細胞第1回国際symposium
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Roles of C-type lectins in the homeostasis of the intestinal immunity.2019

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      NIH-Japan Joint Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The role of CTRP family members in the immune system2019

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 30th Anniversary International Symposium of Research Institute for Biomedical Sciences, Tokyo University of Science
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of Dectin-1-IL-17F axis in the homeostasis of the intestinal immune system.2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第14回日本基礎老化学会大会、第9回東京理科大学総合研究院トランスレーショナルリサーチシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] 炎症性疾患発症におけるIL-17の役割2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第33回日本乾癬学会学術大会特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Analysis of IL-17A and IL-17F expression in APCMin mouse intestinal cancer__model.2018

    • Author(s)
      Yulia Makusheva, Shigeru Kakuta, Ce Tang, Yoichiro Iwakura
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] 関節炎における骨免疫相関2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第36回日本骨代謝学会学術集会/日本炎症再生学会合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Suppression of IL-17F, but not IL-17A, provides protection against colitis by inducing Treg cell through modification of the intestinal microbiota2018

    • Author(s)
      Ce Tang, Shigeru Kakuta, Yoichiro Iwakura
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] 関節炎における骨免疫相関2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第36回日本骨代謝学会学術集会/日本炎症再生学会合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Suppression of IL-17F, but not IL-17A, provides protection against colitis by inducing Treg cell through modification of the intestinal microbiota2018

    • Author(s)
      Ce Tang, Shigeru Kakuta, Yoichiro Iwakura
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Analysis of IL-17A and IL-17F expression in APCMin mouse intestinal cancer__model.2018

    • Author(s)
      Yulia Makusheva, Shigeru Kakuta, Ce Tang, Yoichiro Iwakura
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of CTRP6 in chronic kidney disease progression.2018

    • Author(s)
      紀 熙華, 村山 正承, 岩倉 洋一郎
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Suppression of IL-17F, but not IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota2018

    • Author(s)
      Ce Tang, Shigeru Kakuta, Yoichiro Iwakura
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of CTRP6 in chronic kidney disease progression.2018

    • Author(s)
      紀 熙華, 村山 正承, 岩倉 洋一郎
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Recognition of budding yeast by a C-type lectin gene and its roles in host defense to fungal infection.2018

    • Author(s)
      Soo-Hyun Chung, Yoichiro Iwakura
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Suppression of IL-17F, but not IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota2018

    • Author(s)
      Ce Tang, Shigeru Kakuta, Yoichiro Iwakura
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] 炎症性疾患発症におけるIL-17の役割2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第33回日本乾癬学会学術大会特別講演
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Recognition of budding yeast by a C-type lectin gene and its roles in host defense to fungal infection.2018

    • Author(s)
      Soo-Hyun Chung, Yoichiro Iwakura
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] C型レクチンの真菌感染防御における役割2018

    • Author(s)
      鄭_絢、岩倉洋一郎
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Validation the role of CTRP6 in chronic kidney disease progression.2018

    • Author(s)
      Hsi Hua Chi Masanori A Murayama, Yoichiro Iwakura.
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] C型レクチンの真菌感染防御における役割2018

    • Author(s)
      鄭 琇絢、岩倉洋一郎
    • Organizer
      第47回日本免疫学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] The role of Dectin-1-IL-17F axis in the homeostasis of the intestinal immune system.2018

    • Author(s)
      岩倉洋一郎
    • Organizer
      第14回日本基礎老化学会大会、第9回東京理科大学総合研究院トランスレーショナルリサーチシンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H05045
  • [Presentation] Validation the role of CTRP6 in chronic kidney disease progression.2018

    • Author(s)
      Hsi Hua Chi Masanori A Murayama, Yoichiro Iwakura.
    • Organizer
      The 6th Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02671
  • [Presentation] Dectins and IBD Fungi/Dectins and mucosal immunity2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      18th International Congress of Mucosal Immunity (ICMI2017)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The role of Dectin-1-IL-17F axis in the homeostasis of the intestinal immune system. Inner Cosmos of the Body-Immunity, Tumors and Inflammation-2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      International Symposium of the Center for Animal Disease Models 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性疾患及び免疫系の恒常性維持におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第40回皮膚脈管・膠原病研究会
    • Place of Presentation
      コラッセ福島
    • Year and Date
      2017-01-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Immune and Bone Metabolic Abnormalities in Dcir-deficient Mice.2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本骨代謝学会 学会合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Roles of C-type lectins in the immune system2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      BI/Kyoto University Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 低分子βグルカンによる腸管免疫の制御2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第1回千葉プロバイオティックス学術セミナー
    • Place of Presentation
      千葉県 アパホテル&リゾート東京ベイ幕張
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The role of Dectin-1-IL-17F axis in the homeostasis of the intestinal immune system.2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      International Cytokine Interferon Society Meeting (ICIS)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性疾患発症におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第221回日本皮膚科学会熊本地方会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性疾患および免疫系の恒常性維持におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      乾癬エキスパートミーティング in 関東甲信越
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性腸疾患と食物アレルギーの病態制御におけるDectin-1と短鎖βグルカンの役割の解析2017

    • Author(s)
      唐策、岩倉洋一郎
    • Organizer
      Glyco-Immunology 2017糖鎖免疫研究会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2017-01-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 炎症性疾患および免疫系の恒常性維持におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      ノバルティスTAPの会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性疾患発症におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本炎症再生医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症応答におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      埼玉IL-17Aフォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 低分子βグルカンによる腸管免疫の制御2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第1回プロバイオティクス学術セミナー
    • Place of Presentation
      アパホテル&リゾート東京ベイ幕張
    • Year and Date
      2017-02-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 腸管免疫の恒常性維持におけるC型レクチンおよびIL-17Fの役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本生物学研究所セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Roles of C-type lectins in host defense against pathogens and homeostasis of the immune system.2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Genomics Research Center Seminar Series
    • Place of Presentation
      Taipei, ROC
    • Year and Date
      2017-03-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Novel animal models in arthritis Novel Animal Models in Rheumatoid Arthritis2017

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Joint EULAR-APLAR session, EULAR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性腸疾患と食物アレルギーの病態制御におけるDectin-1と短鎖βグルカンの役割の解析2017

    • Author(s)
      唐策、岩倉洋一郎
    • Organizer
      Glyco-Immunology 2017糖鎖免疫研究会
    • Place of Presentation
      東京都 東京医科歯科大学 M&Dタワー
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症性疾患及び免疫系の恒常性維持におけるIL-17の役割2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第40回皮膚脈管・膠原病研究会
    • Place of Presentation
      福島県 コラッセ福島
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 食品の腸内環境に及ぼす影響と疾病との関連2017

    • Author(s)
      岩倉洋一郎
    • Organizer
      第26回日本臨床環境医学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] シンポジウム17「リウマチ性疾患における自己免疫と自然免疫」2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      第60回日本リウマチ学会総会学術集会
    • Place of Presentation
      神奈川県 パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus-mediated regulatory T cell expansion in the intestine.2016

    • Author(s)
      Ce Tang, Tomonori Kamina, Yoichiro Iwakura.
    • Organizer
      International Congress of Immunology (ICI) 2016
    • Place of Presentation
      Melbourne, Australia.
    • Year and Date
      2016-08-21
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      四国4大学皮膚科研究会
    • Place of Presentation
      愛媛県 松山全日空ホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Pathogenic Mechanisms of Psoriasis: Lessons from Mouse Models2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      日本研究皮膚科学会第41回年次学術大会
    • Place of Presentation
      宮城県 仙台国際センター
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 疾患モデルを用いた自己免疫および感染防御機構の解析と創薬への展開2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      自治医科大学大学院特別講義(医学研究科教育委員会主催)
    • Place of Presentation
      自治医科大学
    • Year and Date
      2016-10-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 低分子βグルカンによる腸管炎症抑制2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      バイオジャパン
    • Place of Presentation
      東京理科大学
    • Year and Date
      2016-10-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells.2016

    • Author(s)
      Aoi Akitsu, Yoichiro Iwakura.
    • Organizer
      International Congress of Immunology (ICI) 2016
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 低分子βグルカンによる腸管炎症抑制2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      バイオジャパン
    • Place of Presentation
      神奈川県 パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 補体制御因子CTRP6と炎症性疾患2016

    • Author(s)
      村山正承、松尾謙蔵、吉田佳織、片桐菜々子、岩倉洋一郎
    • Organizer
      第81回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      長崎大学坂本キャンパス良順会館
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 疾患モデルを用いた自己免疫および感染防御機構の解析と創薬への展開2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      自治医科大学大学院特別講義(医学研究科教育委員会主催)
    • Place of Presentation
      茨城県 自治医科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells.2016

    • Author(s)
      Aoi Akitsu, Yoichiro Iwakura.
    • Organizer
      International Congress of Immunology (ICI) 2016
    • Place of Presentation
      Melbourne, Australia.
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 短鎖βグルカンによる腸管免疫恒常性の維持2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本臨床免疫学会シンポジウム1
    • Place of Presentation
      東京都 京王プラザホテル
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] A novel role of Dectin-1 signaling in controlling food antigen-induced mouse intestinal allergy2016

    • Author(s)
      唐策、濱田有史、岩倉洋一郎
    • Organizer
      第45回日本免疫学会学術集会.
    • Place of Presentation
      沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Complement regulator CTRP6 and inflammatory diseases.2016

    • Author(s)
      Masanori A. Murayama, Kenzo Matsuo, Kaori Yoshida, Nanako Katagiri, Yoichiro Iwakura.
    • Organizer
      9th International Conference on Complement Therapeutics.
    • Place of Presentation
      Rhodes, Greece
    • Year and Date
      2016-06-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Identification of novel IL-17-producing T cell populations, γδ TCR-CD4-CD8- cells, in TCRδ -deficient mice.2016

    • Author(s)
      Aoi Akitsu, Yoichiro Iwakura.
    • Organizer
      4th Annual Meeting of the International Cytokine & Interferon Society (ICIS).
    • Place of Presentation
      San Francisco, USA.
    • Year and Date
      2016-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      Psoriasis and IL-17A Forum 2016 in Kyushu
    • Place of Presentation
      博多エクセルホテル東急
    • Year and Date
      2016-07-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The role of C-type lectin receptors in the homeostasis of the intestinal immune system.2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      National Defense Medical Center (Sponsored by Prof. Ann Chen)
    • Place of Presentation
      Taipei, ROC
    • Year and Date
      2016-09-16
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 補体制御因子CTRP6と炎症性疾患2016

    • Author(s)
      村山正承、岩倉洋一郎
    • Organizer
      第3回日本リウマチ学会ベーシックリサーチカンファレンス.
    • Place of Presentation
      東京都 アキバプラザ
    • Year and Date
      2016-10-14
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] DCIR-糖鎖間相互作用による骨代謝制御機構.2016

    • Author(s)
      矢部力朗、海部知則、丸橋拓海、西城忍、舘野浩章、平林淳、岩倉洋一郎
    • Organizer
      第35回日本糖質年会
    • Place of Presentation
      高知県 高知市文化プラザ
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 短鎖βグルカンによる腸内細菌を介した免疫制御2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      東海大学医学部講演会
    • Place of Presentation
      神奈川県 伊勢原
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自然免疫受容体を介した真菌の認識と免疫系の修飾2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本医真菌学会教育講演3
    • Place of Presentation
      東京都 都立産業貿易センター
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 補体制御因子CTRP6と炎症性疾患2016

    • Author(s)
      村山正承、松尾謙蔵、吉田佳織、片桐菜々子、岩倉洋一郎
    • Organizer
      第81回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      長崎県 長崎大学坂本キャンパス良順会館
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] IL-1Ra KOマウスにおける胸腺T細胞分化の解析2016

    • Author(s)
      秋津葵、 岩倉洋一郎
    • Organizer
      第26回Kyoto T cells conference.
    • Place of Presentation
      京都府 比叡山延暦寺会館
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Identification of novel IL-17-producing T cell populations, γδ TCR-CD4-CD8- cells, in TCRd -deficient mice.2016

    • Author(s)
      Aoi Akitsu, Yoichiro Iwakura.
    • Organizer
      4th Annual Meeting of the International Cytokine & Interferon Society (ICIS).
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-10-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 短鎖βグルカンによる腸管免疫恒常性の維持2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本臨床免疫学会シンポジウム
    • Place of Presentation
      京王プラザ、東京
    • Year and Date
      2016-09-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      Psoriasis and IL-17A Forum 2016 in Kyushu
    • Place of Presentation
      福岡県 博多エクセルホテル東急
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The role of C-type lectin receptors in the homeostasis of the intestinal immune system.2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      National Defense Medical Center (Sponsored by Prof. Ann Chen)
    • Place of Presentation
      Taipei, ROC
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Roles of C-type lectins in host defense against pathogens and homeostasis of the immune system.2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Genomics Research Center Seminar Series
    • Place of Presentation
      Taipei, ROC
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 短鎖βグルカンによる腸内細菌を介した免疫制御2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      東海大学医学部講演会
    • Place of Presentation
      東海大学医学部
    • Year and Date
      2016-09-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 補体制御因子CTRP6と炎症性疾患2016

    • Author(s)
      村山正承、岩倉洋一郎
    • Organizer
      第3回日本リウマチ学会ベーシックリサーチカンファレンス
    • Place of Presentation
      富士ソフト アキバプラザ 5階アキバホール
    • Year and Date
      2016-10-14
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The role of C-type lectin receptors in the homeostasis of the intestinal immune system.2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Korean Society for Biochemistry and Molecular Biology (KSBMB) International Conference 2016
    • Place of Presentation
      Seoul,Korea
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Complement regulator CTRP6 and inflammatory diseases.2016

    • Author(s)
      Masanori A. Murayama, Kenzo Matsuo, Kaori Yoshida, Nanako Katagiri, Yoichiro Iwakura.
    • Organizer
      9th International Conference on Complement Therapeutics. Rhodes, Greece.
    • Place of Presentation
      Rhodes, Greece
    • Year and Date
      2016-06-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      四国4大学皮膚科研究会
    • Place of Presentation
      松山全日空ホテル
    • Year and Date
      2016-07-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] IL-1Ra KOマウスにおける胸腺T細胞分化の解析.2016

    • Author(s)
      秋津葵、岩倉洋一郎
    • Organizer
      第26回Kyoto T cells conference.
    • Place of Presentation
      比叡山延暦寺内比叡山会館
    • Year and Date
      2016-05-13
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 炎症および感染防御におけるIL-17AとIL-17Fの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      皮膚科学会モーニングセミナー
    • Place of Presentation
      京都国際会館
    • Year and Date
      2016-06-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The role of C-type lectin receptors in the homeostasis of the intestinal immune system.2016

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Korean Society for Biochemistry and Molecular Biology (KSBMB) International Conference 2016
    • Place of Presentation
      Korea, Coex, Seoul
    • Year and Date
      2016-05-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      御茶ノ水乾癬勉強会
    • Place of Presentation
      東京都 TKRガーデン・シティー御茶ノ水
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自然免疫受容体を介した真菌の認識と免疫系の修飾2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本医真菌学会教育講演
    • Place of Presentation
      都立産業貿易センター
    • Year and Date
      2016-09-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 炎症および感染防御におけるIL-17AとIL-17Fの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      皮膚科学会モーニングセミナー
    • Place of Presentation
      京都府 京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillusmediated regulatory T cell expansion in the intestine.2016

    • Author(s)
      Ce Tang, Tomonori Kamina, Yoichiro Iwakura.
    • Organizer
      International Congress of Immunology (ICI) 2016
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] Pathogenic Mechanisms of Psoriasis: Lessons from Mouse Models2016

    • Author(s)
      Yoicihiro Iwakura
    • Organizer
      日本研究皮膚科学会第41回年次学術大会
    • Place of Presentation
      仙台国際センター
    • Year and Date
      2016-12-10
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR-糖鎖間相互作用による骨代謝制御機構2016

    • Author(s)
      矢部力朗、海部知則、丸橋拓海、西城忍、舘野浩章、平林淳、岩倉洋一郎
    • Organizer
      第35回日本糖質年会
    • Place of Presentation
      高知市文化プラザかる ぽーと
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] A novel role of Dectin-1 signaling in controlling food antigen-induced mouse intestinal allergy2016

    • Author(s)
      唐策、濱田有史、岩倉洋一郎
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      沖縄県 沖縄コンベンションセンター
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] シンポジウム17「リウマチ性疾患における自己免疫と自然免疫」2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      第60回日本リウマチ学会総会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-04-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫疾患と感染防御におけるIL-17ファミリーの役割2016

    • Author(s)
      岩倉洋一郎
    • Organizer
      御茶ノ水乾癬勉強会
    • Place of Presentation
      TKRガーデンシティー御茶ノ水
    • Year and Date
      2016-05-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      National Defense Medical Center
    • Place of Presentation
      Taipei
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] C型レクチン受容体DCIR欠損マウスで認められた関節強直と骨量増加の病態解析2015

    • Author(s)
      海部知則、丸橋拓海、矢部力朗、鄭琇絢、妹尾彬正、藤門範行、岩倉洋一郎
    • Organizer
      日本リウマチ学会第2回JCRベーシックリサーチカンファレンス
    • Place of Presentation
      東京大学
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 腸管免疫の恒常性維持に於けるC型レクチンの役割2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      千葉大学真菌医学 研究センターセミナー
    • Place of Presentation
      千葉県 千葉大学真菌医学 研究センター
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      International Immunology Society
    • Place of Presentation
      Bamberg・Germany
    • Year and Date
      2015-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] Basic Research for Infection, Inflammation, and Immunity Using Gene-Modified Mice2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Dalian Medical University (Sponsored by Prof. Yigjie Wu)
    • Place of Presentation
      Dalian Medical University
    • Year and Date
      2015-08-30
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫発症における補体第二経路特異的制御因子CTRP6の役割2015

    • Author(s)
      村山正承、吉田佳織、松尾謙蔵、岩倉洋一郎
    • Organizer
      第52回日本補体学会学術集会
    • Place of Presentation
      愛知県名古屋市 名古屋大学医学部附属病院
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-g; production in T cells.2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung,N, Yoichiro Iwakura.
    • Organizer
      第44回日本免疫学会総会・学術集会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 大腸炎発症におけるIL-1受容体II型の機能解析.2015

    • Author(s)
      吉田佳織、清水謙次、村山正承、岩倉洋一郎
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] マウスモデルを用いた関節リウマチ発症機構の解析と治療への応用2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      第26回日本生体防御学会
    • Place of Presentation
      東京都 台東区生涯学習センターミレミアムホール
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自己免疫疾患および感染防御におけるIL-17A、IL-17Fの役割の解明2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      野口英世記念医学賞受賞記念講演
    • Place of Presentation
      福島県 猪苗代町体験交流館学びいなホール
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung,N, Yoichiro Iwakura.
    • Organizer
      第44回日本免疫学会総会・学術集会
    • Place of Presentation
      札幌コンベンションセンター・札幌
    • Year and Date
      2015-11-18
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] 新たな補体制御因子CTRP6による補体制御機構および関節リウマチに対する治療効果の検討.2015

    • Author(s)
      村山正承、岩倉洋一郎
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus-mediated regulatory T cell expansion in the intestine.2015

    • Author(s)
      Ce Tang, Tomonori Kamina, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS).
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-08-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について.2015

    • Author(s)
      久保幸子、海部知則、岩倉洋一郎
    • Organizer
      第62回日本実験動物学会
    • Place of Presentation
      京都テルサ
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-g; production in T cells.2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung,N, Yoichiro Iwakura.
    • Organizer
      第44回日本免疫学会総会・学術集会
    • Place of Presentation
      北海道札幌市 札幌コンベンションセンター
    • Year and Date
      2015-11-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症および感染防御に於けるIL-17AとIL-17Fの機能2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      Psoriasis and IL-17A Forum 2015
    • Place of Presentation
      東京六本木ミッドタウンホール、東京都
    • Year and Date
      2015-03-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells.2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] CTRP6, complement regulator, effectively treats induced arthritis.2015

    • Author(s)
      Masanori Murayama, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について2015

    • Author(s)
      久保幸子、海部知則、岩倉洋一郎.
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ・京都
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] 自己免疫発症における補体第二経路特異的制御因子CTRP6の役割2015

    • Author(s)
      村山正承、吉田佳織、松尾謙蔵、岩倉洋一郎
    • Organizer
      第52回日本補体学会学術集会
    • Place of Presentation
      名古屋大学医学部附属病院
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The role of Dectin-1 in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      International Symposium of the Center for Animal Disease Models 2015
    • Place of Presentation
      Tokyo, Tokyo University of Science, Gakushi-kaikan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自己免疫疾患および感染防御におけるIL-17A、IL-17Fの役割の解明2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      野口英世記念医学賞受賞記念講演
    • Place of Presentation
      猪苗代町体験交流館学びいなホール
    • Year and Date
      2015-11-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] C型レクチン受容体DCIR欠損マウスで認められた関節強直と骨量増加の病態解析2015

    • Author(s)
      海部知則、丸橋拓海、矢部力朗、鄭琇絢、妹尾彬正、藤門範行、岩倉洋一郎
    • Organizer
      日本リウマチ学会第2回JCRベーシックリサーチカンファレンス
    • Place of Presentation
      東京大学・東京
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] 炎症および感染防御に於けるIL-17AとIL-17Fの機能2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      第114回日本皮膚科学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-05-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Shenzhen Institute of Advanced Technology
    • Place of Presentation
      Shenzhen, China
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] IL-17産生性γδT細胞によるIL-1Ra KOマウスの関節炎発症メカニズム.2015

    • Author(s)
      秋津葵、角田茂、 西城忍、 岩倉洋一郎
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京都 東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] C型レクチン受容体DCIR欠損マウスで認められた関節強直と骨量増加の病態解析2015

    • Author(s)
      海部知則、丸橋拓海、矢部力朗、鄭琇絢、妹尾彬正、藤門範行、岩倉洋一郎
    • Organizer
      日本リウマチ学会第2回JCRベーシックリサーチカンファレンス
    • Place of Presentation
      東京都 東京大学内(本郷)鉄門記念講堂, 伊藤謝恩ホール
    • Year and Date
      2015-10-02
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The role of Dectin-1 in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      International Symposium of the Center for Animal Disease Models 2015
    • Place of Presentation
      Gakushi-kaikan, Tokyo
    • Year and Date
      2015-07-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節リウマチのモデル動物 第9回 in vivo実験医学シンポジウム「免疫疾患における動物モデルを用いた病態解明と治療への応用」2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      公益財団法人実験動物中央研究所主催
    • Place of Presentation
      学士会館
    • Year and Date
      2015-12-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Basic Research for Infection, Inflammation, and Immunity Using Gene-Modified Mice2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Dalian Medical University
    • Place of Presentation
      Dalian, China
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] CTRP6: A Novel Complement Regulator. International Symposium on Immune Regulation2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      University of Tsukuba
    • Place of Presentation
      千葉県 千葉大学
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 炎症および感染防御に於けるIL-17AとIL-17Fの機能2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      ふじのくに乾癬Expert Meeting
    • Place of Presentation
      静岡市グランディエール ブケ・トーカイ
    • Year and Date
      2015-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] マウスモデルを用いた関節リウマチ発症機構の解析と治療への応用2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      第26回に本生体防御学会
    • Place of Presentation
      台東区生涯学習センターミレミアムホール
    • Year and Date
      2015-07-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 腸管免疫の恒常性維持に於けるC型レクチンの役割2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      千葉大学真菌医学 研究センターセミナー
    • Place of Presentation
      千葉大学真菌医学研究センター
    • Year and Date
      2015-12-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] CTRP6, complement regulator, effectively treats induced arthritis.2015

    • Author(s)
      Masanori Murayama, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS).
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-08-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 新たな補体制御因子CTRP6による補体制御機構および関節リウマチに対する治療効果の検討.2015

    • Author(s)
      村山正承、岩倉洋一郎
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京都 東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] DCIR maintains bone homeostasis by regulating IFN-γ production in T cells.2015

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Rikio Yabe, Soo-hyun Chung, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS).
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-08-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節リウマチのモデル動物」第9回 in vivo実験医学シンポジウム「免疫疾患における動物モデルを用いた病態解明と治療への応用2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      公益財団法人実験動物中央研究所
    • Place of Presentation
      東京都 学士会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Advanced Institute for Medical Sciences, Dalian Medical University
    • Place of Presentation
      Dalian, China
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Shenzhen Institute of Advanced Technology
    • Place of Presentation
      Chinese Academy of Science, Shenzhen,
    • Year and Date
      2015-12-07
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 大腸炎発症におけるIL-1受容体II型の機能解析2015

    • Author(s)
      吉田佳織、清水謙次、村山正承、岩倉洋一郎
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京都 東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] IL-17産生性γδT細胞によるIL-1Ra KOマウスの関節炎発症メカニズム.2015

    • Author(s)
      秋津葵、角田茂、 西城忍、 岩倉洋一郎.
    • Organizer
      第80回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      東京工業大学
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Advanced Institute for Medical Sciences
    • Place of Presentation
      Dalian Medical University
    • Year and Date
      2015-12-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Inhibition of Dectin-1 signaling ameliorates colitis by inducing Lactobacillus-mediated regulatory T cell expansion in the intestine.2015

    • Author(s)
      Ce Tang, Tomonori Kamina, Yoichiro Iwakura.
    • Organizer
      Third Annual Meeting of the International Cytokine & Interferon Society (ICIS)
    • Place of Presentation
      Bamberg, Germany
    • Year and Date
      2015-10-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05787
  • [Presentation] 自己炎症、自己免疫に於けるIL-1の役割2015

    • Author(s)
      岩倉洋一郎
    • Organizer
      第8回自己炎症疾患研究会
    • Place of Presentation
      フクラシア東京ステーション、東京都
    • Year and Date
      2015-02-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of C-type lectin receptors in the homeostasis of the intestinal immune system2015

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      National Defense Medical Center, (Sponsored by Prof. Ann Chen)
    • Place of Presentation
      National Defense Medical Center, Taipei
    • Year and Date
      2015-08-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 新規大腸炎モデルRag2-/-Il1rn-/-マウスはILC3 細胞由来IL-17A が病態形成に重要な役割を果たしている2015

    • Author(s)
      秋津葵、角田茂、 西城忍、 岩倉洋一郎.
    • Organizer
      第62回日本実験動物学会
    • Place of Presentation
      京都テルサ
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 遺伝子改変マウスを用いた関節リウマチ発症機構の解析2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      東京理科大学生命医科学研究所ヒト疾患モデル研究センター動物実験棟竣工記念シンポジウム「ヒト疾患モデル研究拠点の構築を目指して」
    • Place of Presentation
      東京理科大学野田薬学部大講堂、千葉県
    • Year and Date
      2014-07-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] マウスモデルを用いた関節リウマチ発症機構の解析2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      第1回アニュアルベーシックコースレクチャー特別講演
    • Place of Presentation
      アキバホール、東京都
    • Year and Date
      2014-10-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 海藻由来βグルカンによる腸管免疫制御2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      第16回マリンバイオテクノロジー学会大会「マリンバイオ三重2014」シンポジウム「藻類の機能性とバイオリファイナリーへの展開」
    • Place of Presentation
      三重大学生物資源学部、三重県
    • Year and Date
      2014-06-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 自己免疫、及び感染防御に於けるIL-17の役割2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      第10回皮膚免疫疾患研究会
    • Place of Presentation
      ヒルトン大阪、大阪府
    • Year and Date
      2014-04-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 創薬に於ける実験動物の役割2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      第61回日本実験動物学会市民公開講座「人々の健康に貢献する動物実験と実験動物の福祉」
    • Place of Presentation
      札幌コンベンションセンター特別会議場、北海道
    • Year and Date
      2014-05-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 抑制型C型レクチン受容体Dendritic Cell ImmunoReceptor (DCIR)とIFN-γによる骨代謝制御2014

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
    • Organizer
      第181回日仏生物学会例会
    • Place of Presentation
      京都産業大学むすびわざ館、京都
    • Year and Date
      2014-12-06
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] Dectin-1の腸管免疫に果たす役割2014

    • Author(s)
      岩倉洋一郎
    • Organizer
      糖鎖免疫研究会Glyco-Immunology2014
    • Place of Presentation
      東京医科歯科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] IFN-γ is an osteoblatogenic factor for increasing the bone volume in DCIR-deficient mice.2014

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
    • Organizer
      第43回日本免疫学会総会・学術集会
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2014-12-11
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] 自然免疫修飾による健康増進を目指した高機能食品開発の試み2013

    • Author(s)
      岩倉洋一郎
    • Organizer
      アグリビジネス創出フェア
    • Place of Presentation
      東京国際展示場
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Dectin-1 signaling synergistically enhances toll-like receptor-mediated production of interferon beta.2013

    • Author(s)
      Kadoki, M., Sasaki, Y., Tang, C., Kamiya, T., and Iwakura, Y.
    • Organizer
      2013 Inaugural Meeting of the International Cytokine and Interferon Society (ICIS)
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      R & D Center for Biotech Products, National Ilan University, Ilan (Host: Wei-Jung Chen, Director & Prof., Kuo-Feng Hua)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明.2013

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎.
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism.2013

    • Author(s)
      Kaifu T., Maruhashi T, Ma G, Yabe R, Seno A, Iwakura Y.
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] IL-17-producing gamma-delta T cells are crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.2013

    • Author(s)
      Akitsu A., Ishigame H., Kakuta S., Saijo S., Iwakura Y.
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism2013

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Yoichiro Iwakura
    • Organizer
      International Immunology Society
    • Place of Presentation
      Italy
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] Pathways in inflammatory diseases (chair and speaker)2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      15th International Congress of Immunology
    • Place of Presentation
      Milan, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      Infection and Immunity Center, National Yang-Min University, Taipei (Host: Prof. Edmond Shie-Liang, Hsieh & Prof. Prof. Alice Chang)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 東京理科大学生命医科学研究所実験動物学研究部門における遺伝子改変マウスの供給について2013

    • Author(s)
      久保幸子, 海部知則, 立石麻理子, 角田 茂, 岩倉洋一郎
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      筑波
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] マウスを使った関節リウマチ治療法の研究2013

    • Author(s)
      岩倉洋一郎
    • Organizer
      免疫ふしぎ未来2013
    • Place of Presentation
      日本化学未来館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明2013

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      Mackay Medical College, Taipei (Host: Nan-Chi Chan)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 疾患モデルマウスを用いたIL1/IL17ファミリー遺伝子の腸管ポリープ形成における役割.2013

    • Author(s)
      角田茂、鈴木俊佐、佐々木大和、五十嵐哲郎、渋川茉莉、村山正承、秋津葵、岡江寛明、石亀晴道、松本清司、久和茂、岩倉洋一郎.
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大、岐阜
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 遺伝子欠損マウスを用いたIL-1の負の調節因子群の機能解析.2013

    • Author(s)
      五十嵐哲郎、清水謙次、秋津葵、久保幸子、劉陽、中嶋明子、宝来玲子、石亀晴道、松本清司、久和茂、岩倉洋一郎、角田茂.
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大、岐阜
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 東京理科大学生命医科学研究所実験動物学研究部門における遺伝子改変マウスの供給について2013

    • Author(s)
      久保幸子、海部知則、立石麻理子、角田 茂、岩倉洋一郎
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 新たな補体制御因子CTRP6の関節リウマチに対する治療効果2013

    • Author(s)
      村山正承、米沢朋、岩倉洋一郎.
    • Organizer
      第一回筑波大学・東京理科大学生命医科学研究所合同リトリート
    • Place of Presentation
      東京理科大学
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The Roles of IL-1 and IL-17 in the Development of Arthritis and Dermatitis in Animal Models2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      The 8th annual meeting of the Taiwaneese Society for Investigative Dermatology. Lecture Hall, Medical College of National Taiwan University (Shiou-Hwa Jee, President)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      College of Medicine, National Taiwan University, Taipei (Host: Prof. Shu-Wha Lin)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] インターロイキン-1受容体2型欠損マウスにおけるコラーゲン誘導関節炎の増悪化.2013

    • Author(s)
      清水謙次、角田茂、溝呂木暁彦、宝来玲子、中嶋明子、岩倉洋一郎
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      つくば国際会議場
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 腸管免疫に於ける自然免疫の役割2013

    • Author(s)
      岩倉洋一郎
    • Organizer
      北海道大学遺伝子病制御研究所講演会
    • Place of Presentation
      北海道大学遺伝子病制御研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] L-17およびTh17の自己免疫疾患に於ける役割2013

    • Author(s)
      岩倉洋一郎
    • Organizer
      ノバルティスScientific Advisory Meeting, The Prince Tower
    • Place of Presentation
      Sakura Tower Tokyo,高輪
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] CCR8 deficiency causes exacerbation of contact hypersensitivity due to enhanced dendritic cell migration.2013

    • Author(s)
      Yabe, R. Shimizu, K. Shimizu, S. Azechi, S. Choi, BI. Kubo, S. Kakuta, S. Nakae, S. and Iwakura, Y.
    • Organizer
      2013 Inaugural Meeting of the International Cytokine and Interferon Society (ICIS)
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      National Defense Medical Center, Taipei (Host: Prof. Ann Chen)
    • Place of Presentation
      Taipei
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Novel complement regulator CTRP6 effectively treats induced arthritis2013

    • Author(s)
      Iwakura, Y.
    • Organizer
      JSICR-MMCB 2013 Joint Symposium in Tokyo, Toshi Center Hotel
    • Place of Presentation
      Tokyo
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR 欠損マウスを用いたC型レクチン受容体による骨代謝制御機構の解明2013

    • Author(s)
      海部知則, 丸橋拓海, 馬光宇, 矢部力朗, 妹尾彬正, 岩倉洋一郎
    • Organizer
      第60回日本実験動物学会総会
    • Place of Presentation
      筑波
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] Dcir-deficient mice as a novel model for ankylosing spondylitis2013

    • Author(s)
      岩倉洋一郎
    • Organizer
      第57回日本リウマチ学会シンポジウム3
    • Place of Presentation
      京都国際会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 遺伝子改変マウスを用いた創薬標的の探索2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第8回生命資源研究・支援センターシンポジウム
    • Place of Presentation
      熊本大学生命資源研究・支援センター(招待講演)
    • Year and Date
      2012-02-24
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] The Roles of IL-17A and IL-17F in Inflammation, Tumorigenesis, and Host Defense against Pathogens2012

    • Author(s)
      Iwakura, Y.
    • Organizer
      10th joint annual meeting of the interferon and cytokine society and the international society for interferon and cytokine research (Cytokine2012)
    • Place of Presentation
      Geneva, Switzerland
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節炎発症における補体の役割とC1qTNFによる制御2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第40回日本臨床免疫学会シンポジウム2「分子標的治療から見た病態へのアプローチ」
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR is a negative regulator in osteoclastogenesis2012

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      The 15 th Congress of Asia Pacific League of Association for Rheumatology
    • Place of Presentation
      Dead Sea, Jordan
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] C-type Lectin Receptor DCIR and the Complement System as Targets for the Treatment of Rheumatoid Arthritis2012

    • Author(s)
      Iwakura, Y.
    • Organizer
      Translational Inflammation Summit, The International Association of Inflammation Societies (IAIS), “Defining the Frontiers and Translational Pathways of Inflammation Research”
    • Place of Presentation
      Bolton Landing, NY
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Rheumatoid Arthritis Models2012

    • Author(s)
      Iwakura, Y.
    • Organizer
      Novartis IL-17 Scientific Advisory Board
    • Place of Presentation
      Frankfurt, Germany
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節リウマチの動物モデルから得られたものとは?2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第56回日本リウマチ学会総会・学術集会、教育講演
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-24240064
  • [Presentation] 発生工学手法による疾患モデルの作製と発症機構の解析2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第59回日本実験動物学会・第46回日本実験動物技術者協会総会合同大会、安東・田嶋賞受賞講演
    • Place of Presentation
      別府
    • Data Source
      KAKENHI-PROJECT-24240064
  • [Presentation] Animal Models for Rheumatoid Arthritis2012

    • Author(s)
      Iwakura, Y.
    • Organizer
      Basic and Clinical Review Course, The 15th Congress of Asia Pacific League of Associations for Rheumatology (APLAR 2012)
    • Place of Presentation
      Dead Sea, Jordan
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] Roles of IL-17A and IL-17F in host defense against pathogens and intestinal tumors2012

    • Author(s)
      Iwakura, Y.
    • Organizer
      The 34th Naito Conference “Infection, Immunity and their Control for Health: Mucosal Barrier, Pathogen and Vaccine”
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ、札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] DCIR is a negative regulator in osteoclastogenesis2012

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      The 15th Congress of Asia Pacific League of Association for Rheumatology
    • Place of Presentation
      Dead Sea, Jordan
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] The roles of IL-17A and IL-17F in inflammation, tumorigenesis, and host defense against pathogens.2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      Invited lecture at The fourth hospital of Heibei Medical University
    • Place of Presentation
      中国
    • Year and Date
      2012-05-14
    • Data Source
      KAKENHI-PROJECT-24240064
  • [Presentation] 新たな強直性脊椎炎モデル:DCIR欠損マウスの解析2012

    • Author(s)
      丸橋拓海、海部知則、藤門範行、岩倉洋一郎
    • Organizer
      第59回日本実験動物学会総会
    • Place of Presentation
      大分
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] Dendritic Cell ImmunoReceptor (DCIR) negatively regulates osteoclastogeneis2012

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      第41回日本免疫学会総会・学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 疾患モデルを用いた関節リウマチ発症機構の解析2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      筑波大学-東京理科大学生命医科学研究所合同シンポジウム「難治性免疫疾患・アレルギー疾患の克服を目指して」
    • Place of Presentation
      学士会館、東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節炎発症に於ける補体系の役割2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第93回発生工学・疾患モデル研究会“終了記念講演会”
    • Place of Presentation
      ホテル東京ガーデンパレス、東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 新たな強直性脊椎炎モデル:DCIR 欠損マウスの解析2012

    • Author(s)
      丸橋拓海, 海部知則, 藤門範行, 岩倉洋一郎
    • Organizer
      第59回日本実験動物学会総会
    • Place of Presentation
      大分
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 疾患モデルを用いた関節リウマチ発症機構の解析2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第12回臨床免疫セミナー in Kyoto
    • Place of Presentation
      京都
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 関節炎発症に於ける補体の役割とClqTNFによる制御2012

    • Author(s)
      岩倉洋一郎
    • Organizer
      第56回日本リウマチ学会総会・学術集会、シンポジウム20
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-24240064
  • [Presentation] IL-17の感染防御・免疫応答における役割2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      京都大学ウイルス研究所セミナー「ウイルス研究の潮流シリーズ8」
    • Place of Presentation
      京都大学ウイルス研究所会議室(招待講演)
    • Year and Date
      2011-07-27
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Therapeutic targets for rheumatoid arthritis : lessons from animal models2011

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Bio-Rheumatology International Congress(BRIC) Tokyo、The 8th GARN Meeting
    • Place of Presentation
      Hilton Tokyo Bay Hotel
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Gene Manipulated Mice as a Tool for the Analysis of Pathogenesis and the Search for Therapeutic Targets2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      東京大学医科学研究所大学院セミナー
    • Place of Presentation
      東京大学医科学研究所講堂(招待講演)
    • Year and Date
      2011-06-06
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR : A new therapeutic target for autoimmune disorders2011

    • Author(s)
      Rikio Yabe, Guangyu Ma, Noriyuki Fujikado, Tomonori Kaifu, Takumi Maruhashi, Akimasa Seno and Yoichiro Iwakura
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] DCIRリガンドの探索2011

    • Author(s)
      矢部力朗、丸橋拓海、妹尾彬正、馬光宇、海部知則、舘野浩章、平林淳、岩倉洋一郎
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] マウスモデルを用いた関節リウマチ発症機構の解析2011

    • Author(s)
      岩倉洋一郎
    • Place of Presentation
      北海道大学遺伝子病制御研究所(招待講演)
    • Year and Date
      2011-10-21
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Gene manipulated mice as a tool for the analysis of pathogenesis and development of new therapeutics2011

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Animal Research Center
    • Place of Presentation
      Jirin University, Changchun
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR: A new therapeutic target for autoimmune disorders2011

    • Author(s)
      Rikio Yabe, Guangyu Ma, Noriyuki Fujikado, Tomonori Kaifu, Takumi Maruhashi, Akimasa Seno and Yoichiro Iwakura
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 先進的医学研究のための遺伝子改変動物コンソーシアムの設立2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      医科学研究所主催シンポジウム「先進的医学研究のための遺伝子改変動物研究の推進」
    • Place of Presentation
      医科学研究所トミーホール(招待講演)
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclastogenesis2011

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 動物モデルを用いた関節リウマチ発症機構の解析2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      第39回臨床免疫学会(免疫疾患学会連合2011)教育講演
    • Place of Presentation
      京王プラザホテル,東京(招待講演)
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR, a C-type lectin receptor, is a new negative regulator in osteoclastogenesis2011

    • Author(s)
      Tomonori Kaifu, Takumi Maruhashi, Guangyu Ma, Rikio Yabe, Akimasa Seno, Noriyuki Fujikado, Yoichiro Iwakura
    • Organizer
      9th Joint Meeting of the ICS and ISICR
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] 自己免疫性関節炎発症におけるサイトカインの役割2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      東京理科大学生命科学研究科大学院特別講義「免疫記憶・炎症研究の新展開」
    • Place of Presentation
      東京理科大カナル会館(招待講演)
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Roles of IL-17A and IL-17F in inflammation, infection, and tumorigenesis2011

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      JSICR-MMCB2011
    • Place of Presentation
      ANA Gate Tower Hotel Osaka, Osaka(招待講演)
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Therapeutic targets for rheumatoid arthritis : lessons from animal models2011

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      1st Bio-Rheumatology International Congress Tokyo 8th GARN Meeting
    • Place of Presentation
      Hilton Tokyo Bay Hotel, Tokyo(招待講演)
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR欠損マウスは強直性脊椎炎様の病態を示す2011

    • Author(s)
      Maruhashi Takumi, Kaifu Tomonori, Ma guangyu, Seno Akimasa, Fujikado Noriyuki, Iwakura Yoichiro
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] マウスモデルを用いた関節リウマチ発症機構の解析2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      御茶ノ水膠原病・リウマチ内科研究会
    • Place of Presentation
      山野上ホテル,東京,(招待講演)
    • Year and Date
      2011-09-09
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] 先進的医学研究のための遺伝子改変動物研究コンソーシアムの設立2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本学術会議シンポジウム「生命科学の生来に向けたマスタープラン」
    • Place of Presentation
      日本学術会議講堂(招待講演)
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] Development of Th17 cells in the absence of IL-6 in IL-1 receptor antagonist deficient mice2011

    • Author(s)
      岩倉洋一郎
    • Organizer
      日本分子生物学会ワークショップ
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR deficient mice develop ankylosing spondylitis-like pathology in humans2011

    • Author(s)
      Takumi Maruhashi, Noriyuki Fujikado, Tomonori Kaifu, Yoichiro Iwakura
    • Organizer
      9th Joint Meeting of the ICS and ISICR
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] Experimental autoimmune encephalomyelitis is aggravated in DCIR knockout mice2011

    • Author(s)
      妹尾彬正, 海部知則, 藤門範行, 岩倉洋一郎
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] Functional specialization of IL-17A and IL-17F2011

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Sylvester Comprehensive Cancer Center and School of Medicine
    • Place of Presentation
      University of Miami, Miami, U.S.A.(招待講演)
    • Year and Date
      2011-05-12
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] DCIR 欠損マウスは強直性脊椎炎様の病態を示す2011

    • Author(s)
      Maruhashi Takumi, Kaifu Tomonori, Ma guangyu, Seno Akimasa, Fujikado Noriyuki, Iwakura Yoichiro
    • Organizer
      第40回日本免疫学会総会・学術集会
    • Place of Presentation
      幕張
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] DCIR リガンドの探索2011

    • Author(s)
      矢部力朗, 丸橋拓海, 妹尾彬正, 馬光宇, 海部知則, 舘野浩章, 平林淳, 岩倉洋一郎
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] The roles of IL-17A and IL-17F in inflammation and host defense against infection2010

    • Author(s)
      岩倉洋一郎
    • Organizer
      Host and Microbe : New windows on homeostasis, new roads to intervention, 2^<nd> Symposium of the IMSUT & RCAST Global COE
    • Place of Presentation
      Tokyo(JPN)
    • Year and Date
      2010-03-03
    • Data Source
      KAKENHI-PROJECT-20015015
  • [Presentation] The roles of C-type lectins in the host defense against fungal infection2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      ISHAM 2009
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PUBLICLY-21022016
  • [Presentation] The roles of IL-17A and IL-17F in the immune system2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Th17 Cells in Health and Disease, Keystone Symposium
    • Place of Presentation
      British Columbia, Canada
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] The roles of C-type lectins in the host defense against fungal infection and development of autoimmunity.2009

    • Author(s)
      Yoichiro Iwakura.
    • Organizer
      CREST International Symposium: Acquired Immunity and Glycobiology (Organized by Tsubata)
    • Place of Presentation
      Kazusa Academia Park, Chiba
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] 発生工学的アプローチによる創薬ターゲットの探索:関節リウマチをモデルとして2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      第56回日本実験動物学会シンポジウム「発生工学的アプローチによる創薬ターゲットの探索」(大会長:岩倉洋一郎)
    • Place of Presentation
      大宮ソニックシティー、大宮
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The role of DCIR in the development of autoimmune arthritis.2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      RCAI-JSI International Symposium on Immunology 2009
    • Place of Presentation
      Pacifico Yokohama, Yokohama
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The Roles of IL-17A and IL-17F in Inflammation and Host Defense against Bacteria2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 9^<th> World Congress on Inflammation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PUBLICLY-21022016
  • [Presentation] マウスモデルが示す関節リウマチの発症機構と治療への道2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      第53回日本リウマチ学会賞受賞講演、グランドプリンスホテル新高輪
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The roles of C-type lectins in the host defense against fungal infection2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Keynote Lecture, 17th Congress of the International Society for Human and Animal Mycology (ISHAM 2009)
    • Place of Presentation
      Keio Plaza Hotel, Tokyo
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] 強直性脊椎炎様関節炎発症におけるC型レクチンの役割2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      第98回日本病理学会総会ワークショップ
    • Place of Presentation
      京都国際会館、京都
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The roles of IL-17A and IL-17F in the immune system.2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      Th17 Cells in Health and Disease, Keystone Symposium, Fairmont Hotel Vancouver
    • Place of Presentation
      British Columbia, Canada
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] C型レクチン活性化を指標とした機能性食品の開発2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      Bio Japan 2009アカデミックシーズ発表会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The roles of C-type lectins in the host defense against fungal infection2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      ISHAM 2009
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] 発生工学的アプローチによる創薬ターゲットの探索:関節リウマチをモデルとして2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      第56回日本実験動物学会総会
    • Place of Presentation
      大宮
    • Data Source
      KAKENHI-PROJECT-20015015
  • [Presentation] 細菌感染防御におけるIL-17A、およびIL-17Fの役割2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      第82回日本細菌学会総会シンポジウム「細菌感染と自然免疫」
    • Place of Presentation
      名古屋国際会議場
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The Roles of IL-17A and IL-17F in Inflammation and Host Defense against Bacteria2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 9^<th> World Congress on Inflammation
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The Roles of IL-17A and IL-17F in inflammation and host defense against bacteria. Chair man and speaker, Symposium 1: Molecular Basis of Inflammation and Innate Immunity.2009

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 9th World Congress on Inflammation
    • Place of Presentation
      Tokyo, Keio Plaza Hotel, Tokyo
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The Roles of IL-17A and IL-17F in Inflammation and Host Defense against Bacteria2009

    • Author(s)
      岩倉洋一郎
    • Organizer
      The 9^<th> World Congress on Inflammation
    • Place of Presentation
      Tokyo(JPN)
    • Data Source
      KAKENHI-PROJECT-20015015
  • [Presentation] The role of DCIR in the development of autoimmune arthritis2008

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The Australian Health and Medical Research Congress, Brisbane Convention Center
    • Place of Presentation
      Brisbane, Australia
    • Data Source
      KAKENHI-PROJECT-20220009
  • [Presentation] The role of cytokines in the development of autoimmune arthritis.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 2nd East Asian Group of Rheumatology Meeting (EAGOR 2007)
    • Place of Presentation
      Seoul
    • Year and Date
      2007-05-19
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] 関節炎における骨破壊メカニズム2007

    • Author(s)
      岩倉洋一郎
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-25
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Rheumatoid arthritis models generated by using transgenic techniques.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      19th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)
    • Place of Presentation
      Seoul
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Rheumatoid arthritis models generated by using transgenic techniques2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      19th Federation of Asian and Oceanian Biochemists (FAOBMB)
    • Place of Presentation
      Seoul
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and homeostasis of the immune system2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] The role of cytokines in the development of autoimmune arthritis.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 2nd East Asian Group of Rheumatology Meeting (EAGOR 2007)
    • Place of Presentation
      Seoul
    • Year and Date
      2007-05-19
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] The role of cytokies in the development of autoimmune arthritis2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 4th International Leukocyte Signal Transduction Workshop:Clinical Implications of Signalimng Pathwas
    • Place of Presentation
      Rhodes
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and defense agains tinfection and homeostasis of the immune svstem2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and homeostasis of the immune system.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会シンポジウム「Innate immune response and diseases」グランドプリンスホテル新高輪
    • Place of Presentation
      東京
    • Year and Date
      2007-11-20
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The roles of C-type lectins in the development of atoimmunity.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The second international symposium on "Immune Surveillance-Its Cellular and Molecular Basis, Regulation and Maintenance"
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Roles of C-type lectins in immune responses.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第30回日本分子生物学会、第80回日本生化学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] Rheumatoid arthritis models generated by using transgenic techniques2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      19th Federation of Asiall alld Oceanian Biochemists and Molecular Biologists(FAOBMB)
    • Place of Presentation
      Seoul
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the development of atoimmunity2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The second international symposium on "Immune Surveillance-Its Cellular and Molecular Basis, Regulation and Maintenance"
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Roles of C-type lectins in immune responses.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      BMB2007(第30回日本分子生物学会、第80回日本生化学会)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] Roles of C-type lectins in immune responses.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      BMB2007 (第30回日本分子生物学会、第80回日本生化学会)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The role of cytokines in the development of autoimmune arthritis2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 4th International Leukocyte Signal Transduction Workshop; Clinical Implications of Signaling Pathways
    • Place of Presentation
      Rhodes
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and homeostasis of the immune system2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] 関節炎における骨破壊メカニズム2007

    • Author(s)
      岩倉洋一郎
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] 関節炎における骨破壊メカニズム2007

    • Author(s)
      岩倉洋一郎
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] Roles of C-tyype lectins in immune responses2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      BMB2007(第30回日本分子生物学会、第80回日本生化学会)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and homeostasis of the immune system2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-19059006
  • [Presentation] The role of cytokines in the development of autoimmune arthritis.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 4th International Leukocyte Signal Transduction Workshop
    • Place of Presentation
      Rhodes
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] The role of cytokines in the development of autoimune arthritis2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 2nd East Asian Group of Rheumatology Meeting(EAGOR2007)
    • Place of Presentation
      Seoul
    • Year and Date
      2007-05-19
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The role of cytokines in the development of autoimmune arthritis.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 4th International Leukocyte Signal Transduction Workshop: Clinical Implications of Signaling Pathways
    • Place of Presentation
      Rhodes
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The role of cytokines in the development of autoimmune arthritis2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      The 2nd East Asian Group of Rheumatology Meeting (EAGOR 2007)
    • Place of Presentation
      Seoul
    • Year and Date
      2007-05-19
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] The roles of C-type lectins in the host defense against infection and homeostasis of the immune system2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      第37回日本免疫学会総会・学術集会
    • Place of Presentation
      品川
    • Data Source
      KAKENHI-PROJECT-19041025
  • [Presentation] Roles of C-type lectins in immune responses.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      BMB2007(第30回日本分子生物学会、第80回日本生化学会)
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Rheumatoid arthritis models generated by using transgenic techniques.2007

    • Author(s)
      Yoichiro Iwakura
    • Organizer
      19th Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB)
    • Place of Presentation
      Seoul
    • Data Source
      KAKENHI-PROJECT-18060010
  • [Presentation] 関飾炎における骨破壊メカニズム2007

    • Author(s)
      岩倉 洋一郎
    • Organizer
      第22回日本整形外科学会基礎学術集会
    • Place of Presentation
      浜松
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-17390140
  • [Presentation] Dendritic Cell ImmunoReceptor (DCIR) is a negative regulator in balancing bone metabolism

    • Author(s)
      Kaifu T., Maruhashi T, Ma G, Yabe R, Seno A, Iwakura Y
    • Organizer
      International Immunology Society
    • Place of Presentation
      Italy
    • Data Source
      KAKENHI-PROJECT-23500489
  • [Presentation] DCIR欠損マウスで認められた骨量増加メカニズムの解明

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター、北海道
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] Gene manipulated mice as a tool to develop new drugs.

    • Author(s)
      岩倉洋一郎
    • Organizer
      China-US innovation dialogue on gene engineering animal models and medical research international forum.
    • Place of Presentation
      Dalian, China
    • Year and Date
      2014-11-22 – 2014-11-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] The role of Dectin-1 and Dectin-2 in the host defense against fungi and in intestinal immunity.

    • Author(s)
      岩倉洋一郎
    • Organizer
      International Symposium Human Genetics
    • Place of Presentation
      Novosibirsk, Russia
    • Year and Date
      2014-06-23 – 2014-06-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 抑制性C型レクチン受容体DCIRによるIFN-γを介した骨代謝制御機構.

    • Author(s)
      海部知則、丸橋拓海、馬光宇、矢部力朗、妹尾彬正、岩倉洋一郎
    • Organizer
      第79回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      北海道大学医学部学友会館フラテホール、北海道
    • Year and Date
      2014-06-19 – 2014-06-20
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] The role of DCIR in maintaining the homeostasis of the immune system and the bone.

    • Author(s)
      岩倉洋一郎
    • Organizer
      Novo Nordisk Innovation Summit,
    • Place of Presentation
      Institute of Medical Science, University of Tokyo,Tokyo
    • Year and Date
      2014-10-01 – 2014-10-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 免疫系、および骨代謝系の恒常性維持に於けるDCIRの役割

    • Author(s)
      岩倉洋一郎
    • Organizer
      糖鎖科学コンソーシアムシンポジウムー糖鎖創薬を目指して、感染、炎症、免疫と糖鎖科学―、
    • Place of Presentation
      東京医科歯科大学、東京都
    • Year and Date
      2014-12-04 – 2014-12-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • [Presentation] 東京理科大学生命医科学研究所実験動物研究部門における遺伝子改変マウス供給について.

    • Author(s)
      久保幸子、海部知則、立石麻理子、岩倉洋一郎
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター、北海道
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-26430095
  • [Presentation] Pathogenic mechanisms of rheumatoid arthritis revealed by animal models.

    • Author(s)
      岩倉洋一郎
    • Organizer
      The Fourth Bizan Immunology Symposium at University of Tokushima (BISUT4) “Immune System Development, Deviation, and Regulation”
    • Place of Presentation
      Fujii Memorial Hall, University of Tokushima,Tokushima
    • Year and Date
      2015-01-29 – 2015-01-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24220011
  • []

  • []

  • []

  • []

  • 1.  SUDO Katsuko (50126091)
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  • 103.  毛利 秀雄 (70012268)
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  • 104.  浜田 博司 (00208589)
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  • 105.  松澤 昭雄 (50012745)
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  • 106.  鈴木 直義 (10003071)
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  • 107.  志田 壽利 (00144395)
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  • 108.  高松 純樹 (80221365)
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  • 109.  西尾 純子 (40598679)
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    # of Collaborated Products: 1 results
  • 110.  藤尾 圭志 (70401114)
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    # of Collaborated Products: 0 results
  • 111.  柳井 秀元 (70431765)
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    # of Collaborated Products: 1 results
  • 112.  根岸 英雄 (60514297)
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    # of Collaborated Products: 1 results
  • 113.  山本 一彦 (80191394)
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    # of Collaborated Products: 1 results
  • 114.  生島 弘彬 (80719154)
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  • 115.  矢部 力朗 (00598229)
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    # of Collaborated Products: 2 results
  • 116.  村山 正承 (60737675)
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    # of Collaborated Products: 3 results
  • 117.  UEDA Susumu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 118.  SEKI Naohiko
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    # of Collaborated Products: 0 results
  • 119.  TSUJIMOTO Atsumi
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    # of Collaborated Products: 0 results
  • 120.  田代 則雄
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    # of Collaborated Products: 0 results
  • 121.  EGAWA Gyohei
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    # of Collaborated Products: 1 results
  • 122.  KUMAGAI Yutaro
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    # of Collaborated Products: 1 results
  • 123.  MORITA Masanobu
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    # of Collaborated Products: 1 results
  • 124.  ITO Masataka
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    # of Collaborated Products: 1 results
  • 125.  KINJO Yuki
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    # of Collaborated Products: 1 results
  • 126.  HAYAKAWA Yoshihiro
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    # of Collaborated Products: 1 results
  • 127.  TAKUBO Keiyo
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    # of Collaborated Products: 1 results
  • 128.  FURUKAWA Kazuo
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    # of Collaborated Products: 1 results
  • 129.  MATSYBARA Daisuk
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    # of Collaborated Products: 1 results
  • 130.  SAITO Hirohisa
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    # of Collaborated Products: 1 results
  • 131.  NAKAE Susumu
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    # of Collaborated Products: 1 results
  • 132.  SATO Shintaro
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    # of Collaborated Products: 1 results
  • 133.  HORIGUCHI Kazuhide
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  • 134.  SUGIURA Yuki
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  • 135.  Shishikura Maria
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  • 136.  Okada Takako
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  • 137.  Goshima Yoshio
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  • 138.  TACHI Masahiro
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    # of Collaborated Products: 1 results
  • 139.  EMI Kannno
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  • 140.  田邊 賢司
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    # of Collaborated Products: 1 results
  • 141.  真貝 洋一
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    # of Collaborated Products: 1 results
  • 142.  堀江 一郎
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    # of Collaborated Products: 1 results
  • 143.  黒川 峰夫
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    # of Collaborated Products: 1 results
  • 144.  中山 淳
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    # of Collaborated Products: 1 results
  • 145.  久枝 一
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    # of Collaborated Products: 1 results
  • 146.  高原 和彦
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    # of Collaborated Products: 1 results
  • 147.  稲葉 カヨ
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    # of Collaborated Products: 1 results
  • 148.  橋本 大吾
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    # of Collaborated Products: 1 results
  • 149.  中村 岳史
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    # of Collaborated Products: 1 results
  • 150.  佐藤 かおり
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    # of Collaborated Products: 1 results
  • 151.  青葉 孝昭
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    # of Collaborated Products: 1 results
  • 152.  島津 徳人
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    # of Collaborated Products: 1 results
  • 153.  添野 雄一
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    # of Collaborated Products: 1 results
  • 154.  田谷 雄二
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    # of Collaborated Products: 1 results
  • 155.  宮坂 智充
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    # of Collaborated Products: 1 results
  • 156.  芦野 隆
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    # of Collaborated Products: 1 results
  • 157.  上野 圭吾
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    # of Collaborated Products: 1 results
  • 158.  吉田 裕樹
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    # of Collaborated Products: 1 results
  • 159.  山崎 晶
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    # of Collaborated Products: 1 results
  • 160.  吉開 康信
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    # of Collaborated Products: 2 results
  • 161.  松崎 吾朗
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    # of Collaborated Products: 1 results
  • 162.  梅村 正幸
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    # of Collaborated Products: 1 results
  • 163.  熊野 恵城
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    # of Collaborated Products: 1 results
  • 164.  竹宮 孝子
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    # of Collaborated Products: 1 results
  • 165.  深見 希代子
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    # of Collaborated Products: 1 results
  • 166.  那波 宏之
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    # of Collaborated Products: 1 results
  • 167.  曽根 博仁
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    # of Collaborated Products: 1 results
  • 168.  羽入 修
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    # of Collaborated Products: 1 results
  • 169.  赤司 浩一
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    # of Collaborated Products: 1 results
  • 170.  原田 和俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 171.  佐藤 結子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 172.  松下 操
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    # of Collaborated Products: 1 results
  • 173.  堀 正敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 174.  中司 敦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 175.  宇留島 隼人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 176.  野村 政壽
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 177.  三宅 靖延
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 178.  宮部 千恵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 179.  小出 雅則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 180.  中司 寛子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 181.  小松 雅明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 182.  植松 智
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 183.  七野 成之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 184.  山中 恵一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 185.  波部 幸司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 186.  近藤 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 187.  中村 史雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 188.  門口 智泰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 189.  岡本 一男
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 190.  丹野 寛大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 191.  高木 尚之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 192.  中村 由和
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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