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Yaginuma Katsuyuki  柳沼 克幸

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… Alternative Names

YAGINUMA Katsuyuki  柳沼 克幸

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Researcher Number 40182307
Affiliation (Current) 2025: 公益財団法人がん研究会, がん研究所 細胞生物部, 研究員
Affiliation (based on the past Project Information) *help 2018 – 2020: 公益財団法人がん研究会, がん研究所 細胞生物部, 研究員
2012 – 2015: 公益財団法人がん研究会, がん研究所 細胞生物部, 研究員
2009: 財団法人癌研究会, 癌研究所細胞生物部, 研究員
2008: 財団法人癌研究会, 細胞生物部, 研究員
2006 – 2007: 癌研究所, 細胞生物部, 研究員
2004: (財)癌研究会, 癌研究所・細胞生物部, 研究員
2004: Cancer Institute, Dept of Cell Biology, Associatie, 癌研究所細胞生物部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Tumor biology
Except Principal Investigator
Biological Sciences
Keywords
Principal Investigator
転移メカニズム / 同所移植 / ヒト大腸がん / 転移マウスモデル / オルガノイド / EMT / 腫瘍幹細胞 / 播種腫瘍細胞 / 患者由来オルガノイド / 転移モデルマウス … More / 大腸がん / 国際研究者交流 / 動物モデル / 散発性腫瘍 / 小脳髄芽腫 / microglia / CXCR3 signaling / 腫瘍モデルマウス / CXCR3 receptor signaling / 腫瘍微小環境 / Medulloblastoma / Patched1 / がん抑制遺伝子 … More
Except Principal Investigator
PTEN / APC / Patched / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / β-catenin / p53遺伝子 / ノックアウトマウス / PTEN遺伝子 / ARF遺伝子 / VHL遺伝子 / SMAD4遺伝子 / 癌抑制遺伝子 / ジーンターゲティング / βカテニン / シグナル伝達 / モデル動物 / シグナル / ゲノム / 癌 / 遺伝子 / 遺伝学 Less
  • Research Projects

    (5 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (126 People)
  •  Study of the metastatic process in a mouse model transplanted with the organoids derived from human colorectal cancer.Principal Investigator

    • Principal Investigator
      YAGINUMA Katsuyuki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Progression of the sporadic medulloblastoma and its interaction with the microenvironment in a mouse model sysytem.Principal Investigator

    • Principal Investigator
      YAGINUMA Katsuyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Identification of molecular targets for cancer therapeutics through the analysis of tumor formation in mouse models for human carcinogenesis

    • Principal Investigator
      NODA Tetsuo
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Fuctinonal analysis of cancer related genes by targeted mutagenesis in mice

    • Principal Investigator
      NODA Tetsuo
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University

All 2021 2020 2019 2018 2013 2012 Other

All Journal Article Presentation Book

  • [Book] 「疾患モデルの作製と利用-がん」2012

    • Author(s)
      柳沼 克幸、野田 哲生
    • Publisher
      (株) エル・アイ・シー
    • Data Source
      KAKENHI-PROJECT-24501324
  • [Journal Article] Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer2021

    • Author(s)
      Okamoto Takuya、duVerle David、Yaginuma Katsuyuki、Natsume Yasuko、Yamanaka Hitomi、Kusama Daisuke、Fukuda Mayuko、Yamamoto Mayuko、Perraudeau Fanny、Srivastava Upasna、Kashima Yukie、Suzuki Ayako、Kuze Yuuta、Takahashi Yu、Ueno Masashi、Sakai Yoshiharu、Noda Tetsuo、Tsuda Koji、Suzuki Yutaka,Nagayama Satoshi,Yao Ryoji
    • Journal Title

      Stem Cell Reports

      Volume: 16 Issue: 4 Pages: 954-967

    • DOI

      10.1016/j.stemcr.2021.02.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06333, KAKENHI-PROJECT-18H02684, KAKENHI-PROJECT-18K07217, KAKENHI-PROJECT-19K22570, KAKENHI-PROJECT-16H06279, KAKENHI-PROJECT-21H02770
  • [Presentation] 患者由来大腸がんオルガノイド同所移植マウスモデルにおける転移播種細胞の同定2020

    • Author(s)
      岡本 拓也、柳沼 克幸、長山 聡、八尾 良司
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] ヒト大腸がんオルガノイド同所移植マウスモデルにおける転移腫瘍の発生とEMTマーカーの発現2020

    • Author(s)
      柳沼 克幸、岡本 拓也、長山 聡、八尾 良司
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] Mouse model of metastatic colorectal cancer by orthotopic transplantation of patient-derived organoids2019

    • Author(s)
      Takuya Okamoto, Katsuyuki Yaginuma, Satoshi Nagayama, Ryoji Yao
    • Organizer
      The AACR Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] 大腸がんオルガノイドを用いた転移モデルマウス2019

    • Author(s)
      岡本拓也、柳沼克幸、長山聡、鈴木穣、八尾良司
    • Organizer
      新学術領域研究「細胞ダイバース」第2回若手ワークショップ
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] Reproducibility of metastasis of colorectal cancer using the orthotopic transplantation mouse model.2019

    • Author(s)
      岡本 拓也、柳沼 克幸、長山 聡、八尾 良司
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] 患者由来大腸がんオルガノイドを用いた転移モデルマウス2018

    • Author(s)
      岡本 拓也, 八尾 良司、柳沼 克幸、長山 聡
    • Organizer
      第77回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-18K07217
  • [Presentation] モデルマウスの髄芽腫発生過程における免疫応答2013

    • Author(s)
      柳沼 克幸、野田 哲生
    • Organizer
      第72 回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜 横浜市 ( 神奈川 )
    • Data Source
      KAKENHI-PROJECT-24501324
  • [Presentation] 小脳Patched1遺伝子の散発的不活化と髄芽腫の発生2012

    • Author(s)
      柳沼 克幸、河口 徳一、野田 哲生
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌 札幌市( 北海道 )
    • Data Source
      KAKENHI-PROJECT-24501324
  • [Presentation] 小脳髄芽種の散発性マウスモデルを用いた腫瘍微小環境の解析

    • Author(s)
      柳沼 克幸
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      神奈川県 横浜市 パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-24501324
  • [Presentation] Molecular basis underlying the multi-step process in spontaneous medulloblastoma development

    • Author(s)
      Sugitani Y., Yaginuma K., Noda T.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 小脳髄芽腫の散発性マウスモデルを用いた腫瘍微小環境の解析

    • Author(s)
      柳沼克幸
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • 1.  NODA Tetsuo (10183550)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  TAKANO Hiroshi (00241555)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  YAO Ryoji (80291095)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  SUGAWARA Minoru (20311558)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SUZUKI Akira (10311565)
    # of Collaborated Projects: 1 results
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  • 6.  KAMIJO Takehiko (90262708)
    # of Collaborated Projects: 1 results
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  • 7.  IMAI Kohzoh (60117603)
    # of Collaborated Projects: 1 results
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  • 8.  INOUE Junichiro (70176428)
    # of Collaborated Projects: 1 results
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  • 9.  NAKAMURA Takuro (00180373)
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  • 10.  ISHIKAWA Fuyuki (30184493)
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  • 11.  YAMAMURA Kenichi (90115197)
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  • 12.  ARAKI Kimi (90211705)
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  • 13.  TAKAKURA Akira (60167484)
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  • 14.  KATOH Hideki (30142053)
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  • 15.  NAKAGATA Naomi (30159058)
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  • 16.  TOYOKUNI Shinya (90252460)
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  • 17.  WANIBUCHI Hideki (90220970)
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  • 18.  OGAWA Katsuhiro (50045514)
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  • 19.  MITSUMORI Kunitoshi (10239296)
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  • 20.  YAMADA Yasuhiro (70313872)
    # of Collaborated Projects: 1 results
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  • 21.  SHIBUTANI Makoto (20311392)
    # of Collaborated Projects: 1 results
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  • 22.  IMAIDA Katsumi (90160043)
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  • 23.  FUTAKUCHI Mitsuru (60275120)
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  • 24.  KANDA Hiroaki (90260067)
    # of Collaborated Projects: 1 results
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  • 25.  TANAKA Hideo (60470168)
    # of Collaborated Projects: 1 results
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  • 26.  WAKAI Kenji (50270989)
    # of Collaborated Projects: 1 results
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  • 27.  MIKAMI Haruo (10332355)
    # of Collaborated Projects: 1 results
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  • 28.  SUZUKI Sadao (20226509)
    # of Collaborated Projects: 1 results
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  • 29.  MIURA Katsuyuki (90257452)
    # of Collaborated Projects: 1 results
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  • 30.  WATANABE Yoshiyuki (00191809)
    # of Collaborated Projects: 1 results
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  • 31.  ARISAWA Kokichi (30203384)
    # of Collaborated Projects: 1 results
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  • 32.  TANAKA Keitaro (50217022)
    # of Collaborated Projects: 1 results
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  • 33.  TAKEZAKI Toshiro (50227013)
    # of Collaborated Projects: 1 results
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  • 34.  FURUSHO Norihiro (10346786)
    # of Collaborated Projects: 1 results
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  • 35.  NAITO Mariko (10378010)
    # of Collaborated Projects: 1 results
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  • 36.  OHNAKA Keizo (30325518)
    # of Collaborated Projects: 1 results
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  • 37.  KITA Yoshikuni (30147524)
    # of Collaborated Projects: 1 results
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  • 38.  KURIKI Kiyonori (20543705)
    # of Collaborated Projects: 1 results
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  • 39.  TAMAKAOSHI Akiko (90236737)
    # of Collaborated Projects: 1 results
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  • 40.  EGUCHI Hidetaka (00260232)
    # of Collaborated Projects: 1 results
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  • 41.  KUBO Michiaki (30442958)
    # of Collaborated Projects: 1 results
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  • 42.  HAMAJIMA Nobuyuki (30172969)
    # of Collaborated Projects: 1 results
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  • 43.  NAGATA Chisato (30283295)
    # of Collaborated Projects: 1 results
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  • 44.  HINO Okio (90127910)
    # of Collaborated Projects: 1 results
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  • 45.  TAHARA Hidetoshi (00271065)
    # of Collaborated Projects: 1 results
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  • 46.  SUGIMURA Haruhiko (00196742)
    # of Collaborated Projects: 1 results
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  • 47.  TSUGANE Shoichiro (40179982)
    # of Collaborated Projects: 1 results
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  • 48.  NAKATOCHI Masahiro (10559983)
    # of Collaborated Projects: 1 results
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  • 49.  TAKAYAMA Tetsuji (10284994)
    # of Collaborated Projects: 1 results
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  • 50.  AKAZA Hideyuki (70010486)
    # of Collaborated Projects: 1 results
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  • 51.  TAKAHASHI Satoru (50197141)
    # of Collaborated Projects: 1 results
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  • 52.  TSUKAMOTO Taiji (50112454)
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  • 53.  NAITO Seiji (40164107)
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  • 54.  MASUMORI Naoya (20295356)
    # of Collaborated Projects: 1 results
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  • 55.  YOKOMIZO Akira (60346781)
    # of Collaborated Projects: 1 results
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  • 56.  NAMIKI Mikio (70155985)
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  • 57.  FUJIMOTO Kiyohide (50264867)
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  • 58.  FUJIOKA Tomoaki (80173409)
    # of Collaborated Projects: 1 results
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  • 59.  HORIE Shigeo (40190243)
    # of Collaborated Projects: 1 results
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  • 60.  MORI Mitsuru (50175634)
    # of Collaborated Projects: 1 results
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  • 61.  MORIWAKI Hisataka (50174470)
    # of Collaborated Projects: 1 results
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  • 62.  Shimizu Masahito (90402198)
    # of Collaborated Projects: 1 results
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  • 63.  KANNAGI Mari (80202034)
    # of Collaborated Projects: 1 results
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  • 64.  ISHIDA Takashi (80405183)
    # of Collaborated Projects: 1 results
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  • 65.  MATSUOKA Masao (10244138)
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  • 66.  YAMAOKA Shoji (90263160)
    # of Collaborated Projects: 1 results
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  • 67.  TANAKA Yuetsu (30163588)
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  • 68.  WATANABE Toshiki (30182934)
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  • 69.  YASUI Hiroshi (40448593)
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  • 70.  TSUCHIYA Eiju (00072314)
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  • 71.  DAIGO Yataro (30345029)
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  • 72.  MIYAGI Yohei (00254194)
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  • 73.  TAKAHASHI Takashi (50231395)
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  • 74.  YAMORI Takao (60200854)
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  • 75.  SEIMIYA Hiroyuki (50280623)
    # of Collaborated Projects: 1 results
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  • 76.  UEHARA Yoshimasa (50160213)
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  • 77.  YOSHIDA Minoru (80191617)
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  • 78.  IMOTO Masaya (60213253)
    # of Collaborated Projects: 1 results
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  • 79.  FUKAZAWA Hidesuke (10218878)
    # of Collaborated Projects: 1 results
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  • 80.  KAKEYA Hideaki (00270596)
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  • 81.  DAN Shingo (70332202)
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  • 82.  TOMIDA Akihiro (40251483)
    # of Collaborated Projects: 1 results
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  • 83.  KAWADA Manabu (20300808)
    # of Collaborated Projects: 1 results
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  • 84.  OSADA Hiroyuki (80160836)
    # of Collaborated Projects: 1 results
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  • 85.  MATSUURA Masaaki (40173794)
    # of Collaborated Projects: 1 results
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  • 86.  MIZUKAMI Tamio (80367896)
    # of Collaborated Projects: 1 results
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  • 87.  MASHIMA Tetsuo (30311228)
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  • 88.  USHIJIMA Masaru (60328565)
    # of Collaborated Projects: 1 results
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  • 89.  TOKINO Takashi (40202197)
    # of Collaborated Projects: 1 results
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  • 90.  SUZUKI Hiromu (20381254)
    # of Collaborated Projects: 1 results
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  • 91.  SHINOMURA Yasuhisa (90162619)
    # of Collaborated Projects: 1 results
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  • 92.  NOSHO Katsuhiko (10597339)
    # of Collaborated Projects: 1 results
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  • 93.  MIYAZONO Kohei (90209908)
    # of Collaborated Projects: 1 results
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  • 94.  INAZAWA Johji (30193551)
    # of Collaborated Projects: 1 results
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  • 95.  HIROTA Toru (50421368)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 96.  SUZUKI Misao (60253720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 97.  TAKEDA Naoki (90304998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 98.  SUGITANI Yoshinobu (80360569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 99.  ITO Hidemi (90393123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 100.  HOSONO Satoyo (80402600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 101.  IWASAKI Motoki (60392338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 102.  NAGASE Hiroki (90322073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 103.  NISHITA Hiroki (40531257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 104.  KONO Suminori (70128015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 105.  HASHIMOTO Syuji (50148334)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 106.  YAMAGUCHI Kazunari (20128325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 107.  TAKANO Atsushi (50582607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 108.  TERAMOTO Koji (10452244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 109.  MATSUDA Koichi (90401257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 110.  TANAKA Yukichi (50420691)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 111.  AOKI Ichiro (00184028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 112.  OSAMURA Yoshiyuki (10100992)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 113.  NAKAMURA Naoya (50227922)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 114.  SUZUKI Noboru (40235982)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 115.  TAJIRI Michihiko (00449117)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 116.  KAWASAKI Takashi (20377188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 117.  YOKOSE Tomoyuki (10221665)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 118.  YANAGISAWA Kiyoshi (20372112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 119.  HIRAKAWA Akihiro (90609330)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 120.  IIJIMA Yoshihiko (50584679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 121.  ZEMBUTSU Hitoshi (90372820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 122.  SASAKI Yasushi (70322328)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 123.  IDOGAWA Masashi (00404749)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 124.  MARUYAMA Reo (60607985)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 125.  KAI Masahiro (80260777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 126.  中村 祐輔 (70217909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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