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Yasui Hiroshi  安井 寛

… Alternative Names

YASUI Hiroshi  安井 寛

安井 寛

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Researcher Number 40448593
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0905-6855
Affiliation (Current) 2025: 聖マリアンナ医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2024: 聖マリアンナ医科大学, 医学部, 教授
2020 – 2023: 東京大学, 医科学研究所, 特任准教授
2022: 聖マリアンナ医科大学, 医学部, 准教授
2018: 東京大学, 医科学研究所, 特任准教授
2015 – 2016: 東京大学, 医科学研究所, 特任准教授 … More
2012 – 2014: 東京大学, 医科学研究所, 特任講師
2010 – 2011: 札幌医科大学, 道民医療推進学講座, 助教
2007 – 2008: Sapporo Medical University, 医学部, 研究員 Less
Review Section/Research Field
Principal Investigator
Hematology
Except Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Tumor therapeutics / Laboratory medicine
Keywords
Principal Investigator
多発性骨髄腫 / 血液内科学 / 免疫細胞 / 改変抗体 / がん免疫療法 / 三重特異性抗体 / 橋渡し研究 / 抗体医薬 / デキサメサゾン感受性 / 次世代シーケンサー … More / 染色体異常 / ゲノムワイド / 抗癌剤感受性 / 脱メチル化剤 / DNAメチル化 / 難治性形質細胞疾患 / トランスレーショナルリサーチ / エピジェネティック / 遺伝子発現プロファイル / アポトーシス / 薬剤耐性 / lenalidomide / サリドマイド誘導体 … More
Except Principal Investigator
大規模ゲノム解析・オミックス解析 / 一般健常人 / 臨床検体 / コホート / 生体試料支援 / 多発性骨髄腫 / オミックス解析 / 大規模ゲノム解析 / 最先端解析技術支援 / ブレインバンク / 健常人コホート / 倫理・法・社会的検討 / バイオメディカルデータ解析支援 / 剖検脳組織 / 治療抵抗性 / 免疫チェックポイント / HDAC阻害剤 / 抗体療法 / FLT3 / レナリドミド / セレブロン / CUDC-907 / HDAC阻害薬 / AKT / HDAC / NK-92 / DNAM-1 / CD112 / CD155 / Acute myeloid leukemia / Akt inhibitor / HDAC inhibitor / MM / CD155/CD112 / TIGIT / AML / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / 核酸治療 / 抗体医薬 / DDS / 免疫細胞 / 骨髄微小環境 / 橋渡し研究 / Drug Delivery System / 分子診断 / ヒストンアセチル化 / マイクロRNA / SUVH20 / クロマチン構造 / 酸化ストレス / 小胞体ストレス / ヒストンメチル化 Less
  • Research Projects

    (9 results)
  • Research Products

    (103 results)
  • Co-Researchers

    (173 People)
  •  Platform of Supporting Cohort Study and Biospecimen Analysis

    • Principal Investigator
      醍醐 弥太郎, 村上 善則
    • Project Period (FY)
      2022 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
    • Research Institution
      The University of Tokyo
  •  Strategy to overcome the refractoriness of hematological malignancies through inhibition of intracellular signaling and immune enhancement

    • Principal Investigator
      Imai Yoichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Dokkyo Medical University
      The University of Tokyo
  •  Platform of Supporting Cohort Study and Biospecimen Analysis

    • Principal Investigator
      MURAKAMI Yoshinori, 今井 浩三
    • Principal Investigator(Support)
      IMAI Kohzoh
    • Project Period (FY)
      2016 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
    • Research Institution
      The University of Tokyo
  •  A fundamental study to develop novel targeted drug delivery systems for multiple myeloma therapy

    • Principal Investigator
      Imai Kohzoh
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      The University of Tokyo
  •  Development of trifunctional antibodies in multiple myelomaPrincipal Investigator

    • Principal Investigator
      YASUI Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Analysis of epigenetic aberration in plasma cell dyscrasiaPrincipal Investigator

    • Principal Investigator
      YASUI Hiroshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Molecular diagnosis by evaluating histone methylation

    • Principal Investigator
      ADACHI Masaaki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Sapporo Medical University
  •  Analysis of lenalidomide-resistance in multiple myelomaPrincipal Investigator

    • Principal Investigator
      YASUI Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 抗体医薬 PHARM TECH JAPAN臨時増刊号「日本DDS学会創立30周年記念誌」2015

    • Author(s)
      安井 寛、今井浩三
    • Total Pages
      282
    • Publisher
      株式会社じほう
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] 多発性骨髄腫に対する新たな抗体医薬開発の現状 血液内科 特集「新規ターゲットおよび医薬品による血液がん治療の新たな展開」2015

    • Author(s)
      安井寛, 石田禎夫
    • Total Pages
      284
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Book] 多発性骨髄腫に対する新たな抗体医薬開発の現状 血液内科 特集「新規ターゲットおよび医薬品による血液がん治療の新たな展開」2015

    • Author(s)
      安井 寛、石田禎夫
    • Total Pages
      284
    • Publisher
      科学評論社
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] 核酸を用いるDDS治療の現状と将来 医薬ジャーナル 特集「Drug delivery system (DDS) の最新展望」2014

    • Author(s)
      安井寛
    • Total Pages
      200
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Book] Multiple Myeloma: Risk Factors, Diagnosis and Treatments (The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myeloma)2014

    • Author(s)
      Yasui H, Ishida T, Imai K
    • Total Pages
      249
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] 核酸を用いるDDS治療の現状と将来 医薬ジャーナル 特集「Drug delivery system (DDS) の最新展望」2014

    • Author(s)
      安井 寛
    • Total Pages
      200
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] The Role of DNA Methylation in the Genetics and Epigenetics of Multiple Myelome2014

    • Author(s)
      Yasui H, Ishida T, Imai K
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] Multiple myeloma: risk factors, diagnosis and treatments.(The role of DNA methylation in the genetics and epigenetics of multiple myeloma.)2014

    • Author(s)
      Yasui H, Ishida T, Imai K.
    • Total Pages
      249
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Book] 抗がん細胞抗体-その開発のあゆみとがん抗体療法の新たな可能性 実験医学増刊「腫瘍免疫学とがん免疫療法」2013

    • Author(s)
      安井 寛、今井浩三
    • Total Pages
      230
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] 抗体を用いたターゲッティング 応用が拡がるDDS 人体環境から農業・家電まで-2013

    • Author(s)
      安井 寛, 今井浩三
    • Total Pages
      578
    • Publisher
      エヌ・ティー・エヌ
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Book] 造血器腫瘍とエピジェティクス-治療への応用と新たな展開-2012

    • Author(s)
      安井寛、石田禎夫
    • Publisher
      医薬ジャーナル社(印刷中)
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Book] II-3.発症機構とエピジェティックス異常6)多発性骨髄腫.造血器腫瘍とエピジェティクス-治療への応用と新たな展開-2012

    • Author(s)
      安井寛, 石田禎夫
    • Publisher
      医薬ジャーナル社(in press)
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Book] 造血器腫瘍とエピジェティクス-治療への応用と新たな展開-2012

    • Author(s)
      安井 寛、石田禎夫 ら
    • Total Pages
      251
    • Publisher
      医薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Journal Article] STAT1/3 signaling suppresses axon degeneration and neuronal cell death through regulation of NAD+-biosynthetic and consuming enzymes2023

    • Author(s)
      Murata Hitoshi、Yasui Yu、Oiso Kazuma、Ochi Toshiki、Tomonobu Nahoko、Yamamoto Ken-ichi、Kinoshita Rie、Sakaguchi Masakiyo
    • Journal Title

      Cellular Signalling

      Volume: 108 Pages: 110717-110717

    • DOI

      10.1016/j.cellsig.2023.110717

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K14595, KAKENHI-PROJECT-23K06717, KAKENHI-PROJECT-22K20793, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-23K27439
  • [Journal Article] Small-molecule HDAC and Akt inhibitors suppress tumor growth and enhance immunotherapy in multiple myeloma2021

    • Author(s)
      Hirano Mitsuhito、Imai Yoichi、Kaito Yuta、Murayama Takahiko、Sato Kota、Ishida Tadao、Yamamoto Junichi、Ito Takumi、Futami Muneyoshi、Ri Masaki、Yasui Hiroshi、Denda Tamami、Tanaka Yukihisa、Ota Yasunori、Nojima Masanori、Kamikubo Yasuhiko、Gotoh Noriko、Iida Shinsuke、Handa Hiroshi、Tojo Arinobu
    • Journal Title

      Journal of Experimental & Clinical Cancer Research

      Volume: 40 Issue: 1 Pages: 110-110

    • DOI

      10.1186/s13046-021-01909-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H05667, KAKENHI-PROJECT-18H02679, KAKENHI-PROJECT-19K22557, KAKENHI-PUBLICLY-20H05029, KAKENHI-PROJECT-21H02761, KAKENHI-PROJECT-20K08726
  • [Journal Article] Circulating cell-free DNA in the peripheral blood plasma of patients is an informative biomarker for multiple myeloma relapse2021

    • Author(s)
      Yasui Hiroshi、Kobayashi Masayuki、Sato Kota、Kondoh Kanya、Ishida Tadao、Kaito Yuta、Tamura Hideto、Handa Hiroshi、Tsukune Yutaka、Sasaki Makoto、Komatsu Norio、Tanaka Norina、Tanaka Junji、Kizaki Masahiro、Kawamata Toyotaka、Makiyama Junya、Yokoyama Kazuaki、Imoto Seiya、Tojo Arinobu、Imai Yoichi
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 26 Issue: 11 Pages: 2142-2150

    • DOI

      10.1007/s10147-021-01991-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H05667, KAKENHI-PROJECT-20K08726
  • [Journal Article] Cytotoxic Effects of Alcohol Extracts from a Plastic Wrap (Polyvinylidene Chloride) on Human Cultured Liver Cells and Mouse Primary Cultured Liver Cells2020

    • Author(s)
      Yamamoto KI, Kagawa H, Arimoto S, Tan XW, Yasui K, Oshiki T, Sakaguchi M.
    • Journal Title

      Acta Medica Okayama

      Volume: 74 Issue: 4 Pages: 327-334

    • DOI

      10.18926/AMO/60371

    • NAID

      120006880210

    • URL

      https://ousar.lib.okayama-u.ac.jp/60371

    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-16H06277
  • [Journal Article] Impact of the ESM-1 Gene Expression on Outcomes in Stage II/III Gastric Cancer Patients Who Received Adjuvant S-1 Chemotherapy2020

    • Author(s)
      Kano K, Sakamaki K, Oue N, Kimura Y, Hashimoto I, Hara K, Maezawa Y, Aoyama T, Fujikawa H, Hiroshima Y, Yamada T, Tamagawa H, Yamamoto N, Ogata T, Cho H, Ito H, Shiozawa M, Yukawa N, Yoshikawa T, Morinaga S, Rino Y, Yasui W, Masuda M, Miyagi Y, Oshima T.
    • Journal Title

      In vivo

      Volume: 34 Issue: 1 Pages: 461-467

    • DOI

      10.21873/invivo.11796

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10600, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03774, KAKENHI-PROJECT-19H03443
  • [Journal Article] High gamma-glutamyl hydrolase and low folylpolyglutamate synthetase expression as prognostic biomarkers in patients with locally advanced gastric cancer who were administrated postoperative adjuvant chemotherapy with S-12020

    • Author(s)
      Maezawa Y, Sakamaki K, Oue N, Kimura Y, Hashimoto I, Hara K, Kano K, Aoyama T, Hiroshima Y, Yamada T, Yamamoto N, Ogata T, Ito H, Cho H, Shiozawa M, Yoshikawa T, Morinaga S, Rino Y, Yausi W, Masuda M, Miyagi Y, Oshima T
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 146 Issue: 1 Pages: 75-86

    • DOI

      10.1007/s00432-019-03087-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03774
  • [Journal Article] linical significance of glioma-associated oncogene 1 expression in patients with locally advanced gastric cancer administered adjuvant chemotherapy with S-1 after curative surgery2020

    • Author(s)
      Hashimoto I, Oue N, Kimura Y, Hiroshima Y, Hara K, Maezawa Y, Kano K, Fujikawa H, Aoyama T, Numata M, Yamada T, Tamagawa H, Yamamoto N, Ogata T, Shiozawa M, Morinaga S, Rino Y, Yasui W, Masuda M, Miyagi Y, Oshima T
    • Journal Title

      Anticancer Res

      Volume: 40 Issue: 10 Pages: 5815-5821

    • DOI

      10.21873/anticanres.14599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-18K07016, KAKENHI-PROJECT-16H06277
  • [Journal Article] Clinical significance of KIAA1199 as a novel target for gastric cancer drug therapy2019

    • Author(s)
      Oneyama M, Sakamoto N, Oue N, Kimura Y, Hiroshima Y, Hashimoto I, Hara K, Maezawa Y, Kano K, Aoyama T, Fujikawa H, Yamada T, Tamagawa H, Yamamoto N, Ogata T, Cho H, Ito H, Yukawa N, Shiozawa M, Yoshikawa T, Morinaga S, Rino Y, Masuda M, Miyagi Y, Yasui W, Oshima T
    • Journal Title

      Anticancer Res

      Volume: 39 Issue: 12 Pages: 6567-6573

    • DOI

      10.21873/anticanres.13872

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-17K10600, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03774
  • [Journal Article] Clinical Significance of PRKCI Gene Expression in Cancerous Tissue in Patients With Gastric Cancer2019

    • Author(s)
      HASHIMOTO ITARU、SAKAMAKI KENTARO、OUE NAOHIDE、KIMURA YAYOI、HIROSHIMA YUKIHIKO、HARA KENTARO、MAEZAWA YUKIO、KANO KAZUKI、AOYAMA TORU、YAMADA TAKANOBU、YAMAMOTO NAOTO、OGATA TAKASHI、ITO HIROYUKI、SHIOZAWA MANABU、MORINAGA SOICHIRO、RINO YASUSHI、YASUI WATARU、MASUDA MUNETAKA、MIYAGI YOHEI、OSHIMA TAKASHI
    • Journal Title

      Anticancer Research

      Volume: 39 Issue: 10 Pages: 5715-5720

    • DOI

      10.21873/anticanres.13771

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07016, KAKENHI-PROJECT-17H04280, KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-17K10600, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-19H03774
  • [Journal Article] Myeloma Cells Are Activated in Bone Marrow Microenvironment by the CD180/MD-1 Complex, Which Senses Lipopolysaccharide.2018

    • Author(s)
      Kikuchi J, Kuroda Y, Koyama D, Osada N, Izumi T, Yasui H, Kawase T, Ichinohe T, Furukawa Y.
    • Journal Title

      Cancer Research

      Volume: 78 Issue: 7 Pages: 1766-1778

    • DOI

      10.1158/0008-5472.can-17-2446

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16193, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K09937, KAKENHI-PROJECT-17K09938
  • [Journal Article] Autologous peripheral blood stem cell transplantation for double-refractory myeloma with <i>K-RAS</i> and <i>N-RAS</i> mutations2017

    • Author(s)
      神保光児、横山和明、小川弥穂、平野光人、越智清純、小林真之、遊佐 希、清水英悟、川俣豊隆、大野伸広、山口 類、井元清哉、古川洋一、宮野 悟、今井陽一、東條有伸.
    • Journal Title

      Rinsho Ketsueki

      Volume: 58 Issue: 12 Pages: 2380-2385

    • DOI

      10.11406/rinketsu.58.2380

    • NAID

      130006308839

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21012, KAKENHI-PROJECT-16J02129, KAKENHI-PROJECT-16H06277
  • [Journal Article] HHV-6 encephalitis may complicate the early phase after allogeneic hematopoietic stem cell transplantation: Detection by qualitative multiplex PCR and subsequent quantitative real-time PCR2016

    • Author(s)
      Inazawa N, Hori T, Yamamoto M, Hatakeyama N, Yoto Y, Nojima M, Yasui H, Suzuki N, Shimizu N, Tsutsumi H.
    • Journal Title

      J Med Virol

      Volume: 88 Issue: 2 Pages: 319-323

    • DOI

      10.1002/jmv.24340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      DDS研究30年

      Volume: PHARMA TECH JAPAN 臨時増刊号,31(2)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] 抗体医薬2015

    • Author(s)
      安井寛, 今井浩三
    • Journal Title

      PHARMA TECH JAPAN

      Volume: 31(2) Pages: 94-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26640101
  • [Journal Article] Epstein-Barr Virus-infected Cells in IgG4-related Lymphadenopathy With Comparison With Extranodal IgG4-related Disease.2014

    • Author(s)
      Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Gion Y, Orita Y, Tachibana T, Itoh T, Asano N, Nakamura S, Swerdlow SH, Yoshino T.
    • Journal Title

      Am J Surg Pathol.

      Volume: - Issue: 7 Pages: 946-955

    • DOI

      10.1097/pas.0000000000000206

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402, KAKENHI-PROJECT-24591447, KAKENHI-PROJECT-26293078, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] High Level of Serum Soluble Interleukin-2 Receptor at Transplantation Predicts Poor Outcome of Allogeneic Stem Cell Transplantation for Adult T Cell Leukemia.2014

    • Author(s)
      Shigematsu A, Kobayashi N, Yasui H, Shindo M, Kakinoki Y, Koda K, Iyama S, Kuroda H, Tsutsumi Y, Imamura M, Teshima T.
    • Journal Title

      Biol Blood Marrow Transplant

      Volume: - Issue: 6 Pages: 801-805

    • DOI

      10.1016/j.bbmt.2014.02.014

    • NAID

      120005455889

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591402, KAKENHI-PROJECT-25293217, KAKENHI-PROJECT-25670443, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] DNA synthesis inhibitors for the treatment of gastrointestinal cancer2014

    • Author(s)
      Yasui H, Tsurita G, Imai K
    • Journal Title

      Expert Opin Pharmacother

      Volume: 15 Issue: 16 Pages: 2361-2372

    • DOI

      10.1517/14656566.2014.958074

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402, KAKENHI-PROJECT-26640101, KAKENHI-PROJECT-221S0001
  • [Journal Article] Epstein-Barr virus-infected cells in IgG4-related lymphadenopathy with comparison to extranodal IgG4-related disease2014

    • Author(s)
      Takeuchi M, Sato Y, Yasui H, Ozawa H, Ohno K, Takata K, Iwaki N, Orita Y, Asano N, Nakamura S, Swerdlow SH, Yoshino T
    • Journal Title

      Am J Surg Pathol

      Volume: 38 Pages: 946-955

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Journal Article] Deferasirox induces mesenchymal-epithelial transition in crocidolite-induced mesothelila carcinogenesis in rats.2013

    • Author(s)
      Nagai H, Okazaki Y, Chew SH, Misawa N, Yasui H and Toyokuni S.
    • Journal Title

      Cance Prev Res.

      Volume: 6 Issue: 11 Pages: 1222-1230

    • DOI

      10.1158/1940-6207.capr-13-0244

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-24108008, KAKENHI-PROJECT-24390094, KAKENHI-PROJECT-25860292, KAKENHI-PROJECT-221S0001
  • [Journal Article] Coadministration of tenofovir decreased atazanavir plasma concentration after unilateral nephrectomy.2013

    • Author(s)
      Kunimoto Y, Yasui H, Touda N, Okazaki M, Nakata H, Noda N, Ikeda H, Hayashi T, Takahashi S, Shinomura Y, Ishida T, Miyamoto A.
    • Journal Title

      J Infect Chemother.

      Volume: 19 Issue: 4 Pages: 750-3

    • DOI

      10.1007/s10156-012-0488-2

    • NAID

      10031194406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Journal Article] Model of translational cancer research in multiple myeloma.2012

    • Author(s)
      Yasui H, et al.
    • Journal Title

      Cancer Sci.

      Volume: 103 Pages: 1907-1912

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Journal Article] Model of translational cancer research in multiple myeloma.2012

    • Author(s)
      Yasui H, Ishida T, Maruyama R, Nojima M, Ikeda H, Suzuki H, Hayashi T, Shinomura Y, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 103 Pages: 1207-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Iron overload signature in chrysotile-induced malignant mesothelioma.2012

    • Author(s)
      Jiang L, Akatsuka S, Nagai H, Chew SH, Ohara H, Okazaki Y, Yamashita Y, Yoshikawa Y, Yasui H, Ikuta K, Sasaki K, Kohgo Y, Hirano S, Shinohara Y, Kohyama N, Takahashi T, Toyokuni S.
    • Journal Title

      J Pathol

      Volume: 228 Issue: 3 Pages: 366-77

    • DOI

      10.1002/path.4075

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590394, KAKENHI-PROJECT-23591363, KAKENHI-PROJECT-24390094, KAKENHI-PROJECT-24591377, KAKENHI-PROJECT-221S0001
  • [Journal Article] Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011

    • Author(s)
      Sasaki S., et al
    • Journal Title

      PLoS One

      Volume: 6 Issue: 5 Pages: e19618-e19618

    • DOI

      10.1371/journal.pone.0019618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590853, KAKENHI-PROJECT-22790917, KAKENHI-PROJECT-23240129, KAKENHI-PROJECT-23591399
  • [Journal Article] Epigenetic biomarkers for prediction of sensitivity to chemotherapeutic drugs in multiple myeloma2011

    • Author(s)
      Hiroshi Yasui
    • Journal Title

      Tumor Research

      Volume: 45 Pages: 21-30

    • Data Source
      KAKENHI-PROJECT-22790917
  • [Journal Article] In vitro and in vivo antitumor effects of recombinant bispecific antibodies based on humanized anti-EGFR antibody2011

    • Author(s)
      Watanabe Y, Yasui H, et al
    • Journal Title

      Oncol Rep

      Volume: 26(4) Pages: 949-55

    • DOI

      10.3892/or.2011.1382

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790917, KAKENHI-PROJECT-23591399, KAKENHI-PROJECT-23650227, KAKENHI-PROJECT-23686118, KAKENHI-PROJECT-23790136, KAKENHI-PROJECT-23791512
  • [Journal Article] Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome2010

    • Author(s)
      Miyake N, Yasui H, et al
    • Journal Title

      Hum Mutat

      Volume: 31(8) Issue: 8 Pages: 966-74

    • DOI

      10.1002/humu.21300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Journal Article] PI3K/p110δis a novel therapeutic target in multiple myeloma2010

    • Author(s)
      Ikeda H, Yasui H, et al
    • Journal Title

      Blood

      Volume: 116(9) Issue: 9 Pages: 1460-8

    • DOI

      10.1182/blood-2009-06-222943

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Journal Article] SNX-2112, a selective hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematological tumors by abrogating signaling via Akt and ERK.2009

    • Author(s)
      Okawa Y, Hideshima T, Steed P, Vallet S, Hall S, Huang K, Rice J, Barabasz A, Foley B, Ikeda H, Raje N, Kiziltepe T, Yasui H, Enatsu S, Anderson KC
    • Journal Title

      Blood 113(4

      Pages: 846-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK2009

    • Author(s)
      Okawa Y, Hideshima T, Steed P, Vallet S, Hall S, Huang K, Rice J, Barabasz A, Foley B, Ikeda H, Raje N, Kiziltepe T, Yasui H, Enatsu S, Anderson KC
    • Journal Title

      Blood 113

      Pages: 846-855

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] The monoclonal antibody nBT062 conjugated to cytotoxic maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo.2009

    • Author(s)
      Ikeda H, Hideshima T, Fulciniti M, Lutz RJ, Yasui H, Okawa Y, Kiziltepe T, Vallet S, Pozzi S, Santo L, Perrone G, Tai YT, Cirstea D, Raje NS, Uherek C, Dalken B, Aigner S, Osterroth F, Munshi N, Richardson P, Anderson KC
    • Journal Title

      Clin Cancer Res 15(12)

      Pages: 4028-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.2009

    • Author(s)
      Nojima M, Maruyama R, Yasui H, Suzuki H, Maruyama Y, Tarasawa I, Sasaki Y, Asaoku H, Sakai H, Hayashi T, Mori M, Imai K, Tokino T, Ishida T, Toyota M, Shinomura Y
    • Journal Title

      Clin Cancer Res 15(13)

      Pages: 4356-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Novel molecular -targeted therapeutics for the treatment of cancer.2008

    • Author(s)
      Yasui H, Imai K
    • Journal Title

      Anticancer Agents Med Chem 8(5)

      Pages: 470-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Fatty acid synthase is a novel therapeutic target in multiple myeloma.2008

    • Author(s)
      Okawa Y, Hideshima T, Ikeda H, Raje N, Vallet S, Kiziltepe T, Yasui H, Enatsu S, Pozzi S, Breitkreutz I, Cirstea D, Santo L, Richardson P, Anderson KC
    • Journal Title

      Br J Haematol 141(5)

      Pages: 659-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Fatty acid synthase is a novel therapeutic target in multiple myeloma2008

    • Author(s)
      Okawa Y, Hideshima T, Ikeda H, Raje N, Vallet S, Kiziltepe T, Yasui H, Enatsu S, Pozzi S, Breitkreutz I, Cirstea D, Santo L, Richardson P, Anderson KC.
    • Journal Title

      Br. J. Haematol 141

      Pages: 659-671

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Novel molecular-targeted therapeutics for the treatment of cancer2008

    • Author(s)
      Hiroshi Yasui, et al.
    • Journal Title

      Anti-cancer Agents in Medicinal Chemistry 8

      Pages: 470-80

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells2007

    • Author(s)
      Kiziltepe T, Hideshima T, Ishitsuka K, Ocio EM, Raje N, Catley L, Li CQ, Trudel LJ, Yasui H, Vallet S, Kutok JL, Chauhan D, Mitsiades CS, Saavedra JE, Wogan GN, Keefer LK, Shami PJ, Anderson KC
    • Journal Title

      Blood 110

      Pages: 709-718

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Targeting the beta-catenin/TCF transcriptional complex in the treatment of multiple myeloma2007

    • Author(s)
      Sukhdeo K, Mani M, Zhang Y, Dutta J, Yasui H, Roon e H, Tai YT, Mitsiades C, Anderson KC, Carrasco DR
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 7516-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] 5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.2007

    • Author(s)
      Kiziltepe T, Hideshima T, Catley L, Raje N, Yasui H, Shiraishi N, Okawa Y, Ikeda H, Vallet S, Pozzi S, Ishitsuka K, Ocio EM, Chauhan D, Anderson KC
    • Journal Title

      Mol Cancer Ther 6(6)

      Pages: 1718-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] JS-K, a GST-activated nitric oxide generator, induces DNA double strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells.2007

    • Author(s)
      Kiziltepe T, Hideshima T, Ishitsuka K, Ocio EM, Raje N, Catley L, Li CQ, Trudel LJ, Yasui H, Vallet S, Kutok JL, Chauhan D, Mitsiades CS, Saavedra JE, Wogan GN, Keefer LK, Shami PJ, Anderson KC
    • Journal Title

      Blood 110(2)

      Pages: 709-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] MILN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts2007

    • Author(s)
      Vallet S, Raje N, Ishitsuka K, Hideshima T, Podar K, Chhetri S, Pozzi S, Breitkreutz I, Kiziltepe T, Yasui H, Ocio EM, Shiraishi N, Jin J, Okawa Y, Ikeda H, Mukherjee S, Vaghela N, Cirstea D, Ladetto M, Boccadoro M, Anderson KC
    • Journal Title

      Blood 110

      Pages: 3744-3752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells2007

    • Author(s)
      Hideshima T, Catley L, Raje N, Chauhan D, Podar K, Mitsiades C, Tai YT, Vallet S, Kiziltepe T, Ocio E, Ikeda H, Okawa Y, Hideshima H, Munshi NC, Yasui H, Richardson PG, Anderson KC
    • Journal Title

      Br J Haematol 138

      Pages: 783-791

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma.2007

    • Author(s)
      Podar K, Raab MS, Tonon G, Sattler M, Barila D, Zhang J, Tai YT, Yasui H, Raje N, Depinho RA, Hideshima T, Chauhan D, Anderson KC
    • Journal Title

      Cancer Res 67(4)

      Pages: 1680-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma2007

    • Author(s)
      Neri P, Tassone P, Shammas M, Yasui H, Schipani E, Batchu RB, Blotta S, Prabhala R, Catley L, Hamasaki M, Hideshima T, Chauhan D, Jacob GS, Picker D, Venuta S, Anderson KC, Munshi NC
    • Journal Title

      Leukemia 21

      Pages: 2519-2526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells.2007

    • Author(s)
      Hideshima T, Catley L, Raje N, Chauhan D, Podar K, Mitsiades C, Tai YT, Vallet S, Kiziltepe T, Ocio E, Ikeda H, Okawa Y, Hideshima H, Munshi NC, Yasui H, Richardson PG, Anderson KC
    • Journal Title

      Br J Haematol 138(6)

      Pages: 783-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] がん会子標的治療の発展-抗体医薬を中心に-2007

    • Author(s)
      安井 寛
    • Journal Title

      Focus on Oncology 7

      Pages: 14-15

    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.2007

    • Author(s)
      Vallet S, Raje N, Ishitsuka K, Hideshima T, Podar K, Chhetri S, Pozzi S, Breitkreutz I, Kiziltepe T, Yasui H, Ocio EM, Shiraishi N, Jin J, Okawa Y, Ikeda H, Mukherjee S, Vaghela N, Cirstea D, Ladetto M, Boccadoro M, Anderson KC
    • Journal Title

      Blood 110(10)

      Pages: 3744-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] Biological pathways and in vivo antitumor activity induced by Atiprimod in myeloma.2007

    • Author(s)
      Neri P, Tassone P, Shammas M, Yasui H, Schipani E, Batchu RB, Blotta S, Prabhala R, Catley L, Hamasaki M, Hideshima T, Chauhan D, Jacob GS, Picker D, Venuta S, Anderson KC, Munshi NC
    • Journal Title

      Leukemia 21(12)

      Pages: 2519-2526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Journal Article] 5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells2007

    • Author(s)
      Kiziltepe T, Hideshima T, Catley L, Raje N, Yasui H, Shiraishi N, Okawa Y, Ikeda H, Vallet S, Pozzi S, Ishitsuka K, Ocio EM, Chauhan D, Anderson KC
    • Journal Title

      Mol Cancer Ther 6

      Pages: 1718-1727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma2007

    • Author(s)
      Podar K, Raab MS, Tonon G, Sattler M, Barila D, Zhang J, Tai YT, Yasui H, Raje N, DePinho RA, Hideshima T, Chauhan D, Anderson KC
    • Journal Title

      Cancer Res 67

      Pages: 1680-1688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590566
  • [Journal Article] KC, Carrasco DR. Targeting the {beta}-catenin/TCF transcriptional complex in the treatment of multiple myeloma.2007

    • Author(s)
      Sukhdeo K, Mani M, Zhang Y, Dutta J, Yasui H, Rooney MD, Carrasco DE, Zheng M, He H, Tai YT, Mitsiades C, Anderson KC, Carrasco DR
    • Journal Title

      Proc Natl Acad Sci U S A 104(18)

      Pages: 7516-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] HDAC阻害薬とAKT阻害薬は多発性骨髄腫に対して増殖を抑制し腫瘍免疫を賦活化する2020

    • Author(s)
      平野 光人、今井 陽一、村山 貴彦、佐藤 広太、山本 淳一、伊藤 拓水、二見 宗孔、李 政樹、安井 寛、上久保 靖彦、後藤 典子、石田 禎夫、飯田 真介、半田 宏、東條 有伸
    • Organizer
      第82回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K08726
  • [Presentation] 臨床薬理学集中講座修了後の研究活動 ~橋渡し研究と医師主導治験を中心に~2017

    • Author(s)
      安井 寛
    • Organizer
      第38回日本臨床薬理学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 成人T細胞白血病リンパ腫に合併した急性骨髄性白血病治療中のウィルス感染症の発症2017

    • Author(s)
      神保光児、今井陽一、小川弥穂、平野光人、越智清純、川俣豊隆、横山和明、安井寛、大野伸広、内丸薫、東條有伸
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Toll様受容体CD180を介した多発性骨髄腫の進展機序2017

    • Author(s)
      菊池次郎、黒田芳明、小山大輔、長田直希、和泉透、安井寛、川瀬孝和、一戸辰夫、古川雄祐
    • Organizer
      第42回日本骨髄腫学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 電気泳動法を基盤とする多発性骨髓腫の臨床と研究の進歩~はじめに~2017

    • Author(s)
      安井 寛
    • Organizer
      第68回日本電気泳動学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] Toll様受容体CD180を介した多発性骨髄腫の進展機序2017

    • Author(s)
      菊地次郎、黒田芳明、小山大輔、長田直希、和泉透、安井 寛、川瀬孝和、一戸辰夫, 古川雄祐
    • Organizer
      第79回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] 多発性骨髄腫における先端医療開発の今後2016

    • Author(s)
      安井 寛
    • Organizer
      第67回日本電気泳動学会
    • Place of Presentation
      釧路市観光国際交流センター(北海道釧路市)
    • Year and Date
      2016-08-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-16H06277
  • [Presentation] ラットのアスベスト誘発中皮腫発がんモデルにおいてDeferasirox投与は 間質上皮移行を促進する2013

    • Author(s)
      豊國伸哉、永井裕崇、岡崎泰昌、周 珊瑚、三澤伸明、安井裕之
    • Organizer
      第37回日本鉄バイオサイエンス学会学術集会
    • Place of Presentation
      JA共済ビル・カンファレンスホール、東京
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ターゲッティングのための抗体医薬による新治療戦略.2012

    • Author(s)
      今井浩三、佐々木茂、安井寛、谷口博昭
    • Organizer
      第28回日本DDS学会総会・シンポジウム「ターゲッティング」
    • Place of Presentation
      札幌
    • Year and Date
      2012-07-03
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Methylome analysis by the combination of methylated DNA enrichment and next-generation sequencing in multiple myeloma2011

    • Author(s)
      Nojima M, Yasui H, et al
    • Organizer
      AACR 102nd Annual Meeting 2011
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      2011-04-04
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] Epigenetic changes in repetitive elements are closely associated with genetic and clinical features in multiple myeloma2011

    • Author(s)
      Nojima M, Yasui H, et al
    • Organizer
      The 39th Congress of the ISOBM
    • Place of Presentation
      Firenze, Italy
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 次世代シーケンサーを用いた多発性骨髄腫におけるメチローム解析の試み2011

    • Author(s)
      安井寛, ら
    • Organizer
      第73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫におけるDNA繰り返し配列の低メチル化と染色体異常の関連2011

    • Author(s)
      青木由佳, 安井寛
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] エピゲノム解析による造血器腫瘍の新たな分子標的の同定2011

    • Author(s)
      野島正寛, 安井寛
    • Organizer
      20回日本癌病態治療研究会年会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫におけるDNAメチロームと染色体異常:メチル化DNA結合蛋白を利用した次世代シーケンシングによる検討2011

    • Author(s)
      野島正寛, 安井寛
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫における次世代シーケンサーを利用したメチローム解析2011

    • Author(s)
      野島正寛, 安井寛
    • Organizer
      第5回日本エピジェネティックス研究会年会
    • Place of Presentation
      熊本
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] CD138抗体治療は骨髄微小環境下にいる骨髄腫細胞に対して細胞障害性を持つ2011

    • Author(s)
      池田博, 安井寛ら
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 次世代シーケンサーを用いた多発性骨髄腫におけるメチローム解析の試み2011

    • Author(s)
      安井寛
    • Organizer
      73回日本血液学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 未分化型胃癌におけるDNAメチル化異常の解明2010

    • Author(s)
      高丸博之, 安井寛
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] PI3K/p110δ阻害剤は多発性骨髄腫細胞に対して細胞障害性を有する2010

    • Author(s)
      池田博, 安井寛
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫におけるDNAメチル化遺伝子の網羅的スクリーニングおよびRASD1遺伝子メチル化のデキサメサゾン感受性への関与2010

    • Author(s)
      青木由佳, 安井寛
    • Organizer
      第35回日本骨髄腫研究会総会
    • Place of Presentation
      富山
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] エピゲノム解析による造血器腫瘍の新たな分子標的の同定2010

    • Author(s)
      豊田実, 安井寛
    • Organizer
      第72回日本血液学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫におけるDNAメチル化の網羅的解析と治療抵抗性予測への応用2010

    • Author(s)
      安井寛
    • Organizer
      第61回日本電気泳動学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2010-09-18
    • Data Source
      KAKENHI-PROJECT-22790917
  • [Presentation] 多発性骨髄腫におけるDNA異常メチル化の網羅的解析と、新規メチル化標的遺伝子RASD1.2008

    • Author(s)
      安井寛
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都
    • Year and Date
      2008-10-10
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] 多発性骨髄腫における新規メチル化標的遺伝子RASD1とデキサメサゾン感受性の検討2008

    • Author(s)
      安井寛, ら
    • Organizer
      第33回日本骨髄腫研究会総会
    • Place of Presentation
      広島市
    • Year and Date
      2008-11-15
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] 多発性骨髄腫におけるDNA異常メチル化の網羅的解析と、新規メチル化標的遺伝子2008

    • Author(s)
      安井寛, ら
    • Organizer
      第70回日本血液学会総会
    • Place of Presentation
      京都市
    • Year and Date
      2008-10-11
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] 多発性骨髄種における細胞死抵抗牲とDNAメチル化の役割2007

    • Author(s)
      安井 寛
    • Organizer
      第32回日本骨髄腫研究会絵会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-11
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] Genomic screening for genes silenced by DNA methylation in multiple myeloma.2007

    • Author(s)
      Yasui H.
    • Organizer
      35th Congress of the International Society for Oncodevelopmental Biology and Medicine
    • Place of Presentation
      Czech Republic
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] 多発性骨髄腫における細胞死抵抗性とDNAメチル化の役割2007

    • Author(s)
      安井寛
    • Organizer
      第32回日本骨髄腫研究会総会
    • Place of Presentation
      東京
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] Genomic screening for genes silenced by DNA methylation in multiple myeloma2007

    • Author(s)
      Hiroshi Yasui
    • Organizer
      35th Congress of the International Society for Oncodev-elopmental Biology and Medicine
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-19790673
  • [Presentation] 多発性骨髄腫におけるLINE-1 異常低メチル化と臨床遺伝子学的特徴の相関

    • Author(s)
      野島正寛、青木由佳、安井 寛、丸山玲緒、山本英一郎、麻奥英毅、時野隆至、長村文孝、石田禎夫、今井浩三、篠村恭久、鈴木拓
    • Organizer
      第72回日本癌学会学術集会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] Hypomethylation of Retrotransposons is Correlated with Malignant Levels, Frequency of Chromosomal Aberrations, and Poor Prognosis in Multiple Myeloma.

    • Author(s)
      Yasui H, et al.
    • Organizer
      JSH International Symposium 2012
    • Place of Presentation
      Kawagoe, Japan
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] 多発性骨髄腫におけるDNAメチロームと遺伝子発現・染色体異常との関連

    • Author(s)
      安井 寛ら
    • Organizer
      第37回日本骨髄腫学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] Study of FLC and PIC in immunoglobulin light chain amyloidosis

    • Author(s)
      Yasui H, et al.
    • Organizer
      第74回日本血液学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] A model of Translational Cancer Research in Multiple Myeloma

    • Author(s)
      Yasui H, et al.
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] 多発性骨髄腫における基礎研究の進歩と臨床応用

    • Author(s)
      安井 寛ら
    • Organizer
      第54回日本血液学会秋季北海道地方会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] 多発性骨髄腫におけるゲノム・エピゲノム解析とトランスレーショナルリサーチの試み

    • Author(s)
      安井 寛ら
    • Organizer
      第63回日本電気泳動学会学術集会
    • Place of Presentation
      沖縄県宜野湾市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] トランスレーショナルリサーチの意義と展望

    • Author(s)
      安井寛
    • Organizer
      第23回日本臨床化学会北海道支部例会
    • Place of Presentation
      札幌市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591402
  • [Presentation] Hypomethylation of endogenous retrotransposons is correlated with frequent chromosomal deletions and poor prognosis in multiple myeloma

    • Author(s)
      Yasui H, et al.
    • Organizer
      17th Congress of the European Hematology Association
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-24591402
  • 1.  IMAI Imai (60117603)
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  • 173.  大上 直秀
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