Seimiya Hiroyuki 清宮啓之

… Alternative Names

SEIMIYA Hiroyuki 清宮啓之

清宮啓之セイミヤヒロユキ

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Researcher Number	50280623
Other IDs	https://orcid.org/0000-0003-3314-9736
Affiliation (Current)	2024: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長
Affiliation (based on the past Project Information) *help	2016 – 2024: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 2021: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 2018: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 2011 – 2016: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 2015: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 … More 2013: (公財)がん研, がん化療セ, 分子生物治療 2013: 公益財団法人がん研究会, がん化学療法センター分子生物治療研究部, 部長 2011 – 2012: 公益財団法人がん研究会, がん化学療法センター・分子生物治療研究部, 部長 2009 – 2010: Japanese Foundation For Cancer Research, 癌化学療法センター分子生物治療研究部, 部長 2008 – 2010: Japanese Foundation For Cancer Research, 癌化学療法センター分子生物治療研究部, 部長 2008: Japanese Foundation For Cancer Research, 癌化学療法センター・分子生物治療研究部, 部長 2007: The Cancer Institute of Japanese Foundation of Cancer Research, The Cancer Chemotherapy Center, Chief 2007: Japanese Foundation For Cancer Research, 癌化学療法センター・分子生物治療研究部, 部長 2006 – 2007: 癌研究会, 癌化学療法センター, 部長 2006: (財)癌研究会, 癌化学療法センター・分子生物治療研究部, 部長 2005 – 2006: (財)癌研究会, 癌化学療法センター分子生物治療研究部, 部長 2004: 財団法人癌研究会, 癌化学療法センター・分子生物治療研究部, 部長 2003: 財団法人癌研究会, 癌化学療法センター・基礎研究部, 研究員 2000: 癌研究会, 研究員 1999: 財団法人癌研究会, 癌化学療法センター・基礎研究部, 研究員 1996 – 1998: 癌研究所, 化学療法センター, 研究員 1995 – 1998: 癌研究会, 癌化学療法センター, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 50:Oncology and related fields / Tumor therapeutics / Molecular biology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Science and Engineering / Tumor diagnosis / Biological Sciences / Tumor biology / Clinical oncology / Medical pharmacy / Molecular biology … More Except Principal Investigator … More Medium-sized Section 57:Oral science and related fields / Biological pharmacy / Clinical oncology / Biological Sciences Less
Keywords	Principal Investigator がん / テロメア / タンキラーゼ / 分子標的治療 / テロメラーゼ / PARP / グアニン四重鎖 / 阻害剤 / 細胞分裂 / ポリ(ADP-リボシル)化 … More / DNA損傷 / 分子標的 / 効果予測バイオマーカー / グアニン４重鎖 / ポリ(ADP-リボシル)化酵素 / 創薬 / 染色体 / 老化 / 抗悪性腫瘍薬 / オミクス解析 / バイオプローブ / 天然化合物 / グアニン4重鎖 / 細胞増殖 / 細胞老化 / 抗がん剤 / 遺伝子発現 / 結合蛋白質 / ADP-リボシル化 / TAB182 / アポトーシス / プレシジョン医療 / 薬剤反応性 / 翻訳制御 / 薬物療法 / ケミカルツール分子 / 化学シグナル / 核酸 / 薬剤感受性 / がん細胞 / スクリーニング / shRNAライブラリー / 合成致死 / 転移 / 浸潤 / アクチン / 細胞運動 / G4リガンド / 複製 / 神経膠腫 / がん幹細胞 / 分化 / バイオインフォマティクス / 非コードRNA / 翻訳後修飾 / 細胞死 / バイオマーカー / 脂質 / 酸化ストレス / 活性酸素 / ATP-クエン酸リアーゼ / メタボローム / 微小環境 / 脂質代謝 / 不死化 / 内分泌療法 / ホルモン / アンドロゲン / 前立腺 / ポリADP-リボシル化 / xenograft / ノックアウトマウス / 細胞生物学 / 分子標的療法 / 細胞分化 / 白血病 / チロシンホスファターゼ / 癌 / テロメラーゼ阻害剤 … More Except Principal Investigator 分子探索・プロファイリング / 分子プロファイリング / 生理機能解析 / 病理形態解析 / ゲノム編集 / モデル動物作製 / G-tail / がん幹細胞 / 抗がん剤 / テロメア / テロメラーゼ / 分子標的 / 抗癌剤耐性 / 各プラットフォーム間の連携 / 先進ゲノム解析研究推進 / 先端モデル動物支援 / 先端バイオイメージング支援 / コホート・生体試料支援 / 生命科学連携推進協議会 / ユビキチン分解 / 口腔癌 / 未分化能維持 / 多能性幹細胞 / 行動解析 / 分子探索・ブロファイリング / anticancer drug / telomerase / telomere binding protein / telomere / 老化 / テロメア結合タンパク質 / 癌遺伝子 / 分子標的治療 / がん分子標的治療 / RNAiスクリーニング / 前立腺がん / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / ケミカルバイオロジー / データベース / 研究支援 / スクリーニング / 阻害剤 / 化合物 / 細胞不死化 / 癌早期診断 / 診断マーカー / テロメラーゼ複合体 / テロメラーゼ遺伝子 / HPA法 / TRAP / 制癌剤 / 癌診断法 / hTERT / 癌診断 / 不死化 / 染色体外テロメア断片DNA / テロメア維持機構 / 癌移転 / 癌転移 / アポトーシス / 耐性克服 / 耐性遺伝子 / 耐性タンパク / P-糖タンパク Less

生命科学連携推進協議会
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
先端モデル動物支援プラットフォーム
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
グアニン四重鎖による翻訳制御に潜むがん細胞選択的な脆弱性Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
Molecular basis for cancer precision medicine targeting tankyrase poly(ADP-ribose) polymerasesPrincipal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Investigation of novel molecular targets for oral cancer stem cells and establishment of novel oral cancer treatment strategy
- Principal Investigator
  
  工藤保誠
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  The University of Tokushima
Molecular basis for cancer cell-specific vulnerability to disturbance of G-quadruplex dynamicsPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
Elucidating the functions of quadruplex nucleic acids by integrative molecular profiling of chemical signalsPrincipal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Japanese Foundation for Cancer Research
Optimization of cancer therapeutic strategies that target tankyrase-specific PARylationPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Molecular basis for the cross-sectional vulnerability of various cancers elicited by atypical nucleic acid configuration and its therapeutic applicationPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
Integrative functional analysis of G-quadruplex nucleic acids by utilizing natural and synthetic chemical tool moleculesPrincipal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Japanese Foundation for Cancer Research
Synthetic lethality-based identification of drug-sensitive genome profilesPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Advanced Animal Model Support
- Principal Investigator
  
  INOUE Jun-ichiro, 今井浩三
- Principal Investigator(Support)
  
  IMAI Kohzoh
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  The University of Tokyo
Regulation of cell motility by poly(ADP-ribosyl)ation and its application to overcoming cancer invasion and metastasisPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Development of G-quadruplex ligands that target cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Seimiya Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Japanese Foundation for Cancer Research
Bioinformatics-based functional analysis of telomeric non-coding RNAPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor diagnosis
- Research Institution
  Japanese Foundation for Cancer Research
ポリ（ＡＤＰーリボシル）化による細胞の分裂と運動の制御Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation for Cancer Research
Role of oncogenic factors and their cooperations in survival of prostate tumor-propagating cells
- Principal Investigator
  
  MASHIMA Tetsuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation for Cancer Research
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Development of cancer molecular therapeutics that targets telomere-regulating factorsPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Japanese Foundation For Cancer Research
Lipid metabolomics to analyze the mechanisms for cellular adaptation to tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  公益財団法人がん研究会
   Japanese Foundation For Cancer Research
Development of cancer molecular therapeutics directed to telomeres and cellular senescence svstemsPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
がんの微小環境によるホルモン受容体制御と内分泌がんの生存機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Japanese Foundation For Cancer Research
Multi-functions of tankyrase-1 in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  SEIMIYA Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
染色体末端の維持機構を標的とした癌分子治療法の開発Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
Elucidation of the consequence of telomere single-stand overhang, G-tail, in biology, and application to age-related disease
- Principal Investigator
  
  TAHARA Hidetoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hiroshima University
Development of an information-intensive basis for cancer chemotherapy
- Principal Investigator
  
  YAMORI Takao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
染色体末端の維持機構を標的とした癌分子治療法の開発Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼ1・TAB182の生理機能とその制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼによるテロメア長制御機構とテロメラーゼ阻害剤による制癌Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼによるテロメア長制御機構とテロメラーゼ阻害剤による制癌Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Japanese Foundation For Cancer Research
タンキラーゼ・TAB182の生理機能とその制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
テロメラーゼ機能・テロメア維持機構の解明とその臨床応用
- Principal Investigator
  
  井出利憲
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hiroshima University
テロメラーゼ阻害剤による制癌と癌細胞におけるテロメラーゼ活性制御機構Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Japanese Foundation For Cancer Research
白血病細胞におけるチロシンホスファターゼPTP-U2の発現調節と情報伝達Principal Investigator
- Principal Investigator
  
  清宮啓之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Molecular biology
- Research Institution
  Japanese Foundation For Cancer Research
がん細胞の薬剤感受性と抵抗性の分子機構とその制御
- Principal Investigator
  
  鶴尾隆
- Project Period (FY)
  1994 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo

[Book] 薬剤耐性胃がん細胞のがん幹細胞性とその生存分子経路(がん微小環境に1細胞レベルで挑む)2021
- Author(s)
  馬島哲夫, 清宮啓之
- Total Pages
  220
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16H06276
[Book] がん幹細胞と薬剤耐性「治療標的としてのがん幹細胞」別冊・医学のあゆみ2021
- Author(s)
  馬島哲夫, 清宮啓之
- Total Pages
  132
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-16H06276
[Book] 進化するがん創薬2019
- Author(s)
  清宮啓之（編）
- Total Pages
  344
- Publisher
  化学同人
- ISBN
  4759817336
- Data Source
  KAKENHI-PROJECT-19H03523
[Book] 決定版　阻害剤・活性化剤ハンドブック：テロメラーゼ関連薬剤2019
- Author(s)
  新家一男、清宮啓之（秋山徹、河府和義編）
- Total Pages
  648
- Publisher
  羊土社
- ISBN
  9784758120999
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Book] 進化するがん創薬2019
- Author(s)
  清宮啓之(編)
- Total Pages
  368
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-16H06276
[Book] 進化するがん創薬2019
- Author(s)
  清宮啓之（編）
- Total Pages
  344
- Publisher
  化学同人
- ISBN
  4759817336
- Data Source
  KAKENHI-PROJECT-18K19487
[Book] 進化するがん創薬2019
- Author(s)
  清宮啓之（編）
- Total Pages
  344
- Publisher
  化学同人
- ISBN
  4759817336
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Book] 決定版　阻害剤・活性化剤ハンドブック2019
- Author(s)
  新家一男、清宮啓之（秋山徹、河府和義編）
- Total Pages
  648
- Publisher
  羊土社
- ISBN
  9784758120999
- Data Source
  KAKENHI-PROJECT-18K19487
[Book] ゲノム解析に基づく新しい分子標的治療 : ゲノムワイドな解析および統合的解析による前立腺がん幹細胞の分子標的探索(「がん分子標的治療」)2015
- Author(s)
  馬島哲夫、清宮啓之
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第14報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 癌細胞の不死化と難治性、臨牀と研究902013
- Author(s)
  清宮啓之
- Publisher
  大道学館出版部
- Data Source
  KAKENHI-PROJECT-24650639
[Book] ノーベル賞をもたらしたテロメア研究と癌の診断・治療応用への期待、Surgery Frontier 202013
- Author(s)
  清宮啓之
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-24650639
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤情報支援班報告-制がん候補物質のスクリーニング成績・第14報-2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] がんと脂質代謝実験医学 302012
- Author(s)
  右田敏郎、馬島哲夫、清宮啓之
- Data Source
  KAKENHI-PROJECT-23501319
[Book] テロメアの維持と細胞の分裂寿命、「がん増殖と悪性化の分子機構」2012
- Author(s)
  清宮啓之(編者:宮澤恵二・伊東進)
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-24650639
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-2010
- Author(s)
  矢守隆夫、上原至雅、吉田稔、井本正哉、清宮啓之、水上民夫、川田学、長田裕之、松浦正明、深澤秀輔
- Total Pages
  158
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報2010
- Author(s)
  矢守隆夫、上原至誠、吉田稔、井本正哉、清宮啓之、水上民夫, 他
- Total Pages
  158
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第13報-, 37)2010
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明, 深澤秀輔
- Data Source
  KAKENHI-PROJECT-17012025
[Book] Tankyrase 1, telomere-binding proteins, and inhibitors. In "Telomeres and telomerase in cancer"(Hiyama K Ed.)2009
- Author(s)
  Seimiya H
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tankyrases. In "Encyclopedia of cancer 2nd ed."(Schwab M Ed.)2009
- Author(s)
  Seimiya H
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Telomeres and Telomerase in Cancer(Keiko Hiyama 編, telomere binding proteins, and inhibitors.)2009
- Author(s)
  Seimiya H, Tsuruo T. Tankyrase 1
- Total Pages
  380
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-17012025
[Book] Telomeres and Telomerase in Cancer(Tankyrase 1, telomere-binding proteins, and inhibitors)(edited by Hiyama K)2009
- Author(s)
  Seimiya H, Tsuruo T
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-19370078
[Book] "Telomeresand telomerase in cancer" Tankyrase 1, telomere binding proteins, and inhibitors2009
- Author(s)
  Seimiya H, Tsuruo T.
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-17012025
[Book] Telomeres and Telomerase in Cancer, Edited by Hiyama K, 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tanlyrase l,telo,ere-binding proteins, and inhibitors.(Hiyama, K., editor., Telomeres and Telomerase in Cancer.)2009
- Author(s)
  Seimiya, H., Tsuruo T.
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-20015047
[Book] Tankyrases.(Schwab, M., editor., Encyclopedia of Cancer.2nd ed.)2009
- Author(s)
  Seimiya, H.
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20015047
[Book] 生命の科学(テロメア長の制御機構, 59)2008
- Author(s)
  清宮啓之
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20015047
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-.2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明.
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 癌と化学療法(特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告-制がん候補物質のスクリーニング成績・第12報-, 34)2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
- Data Source
  KAKENHI-PROJECT-17012025
[Book] 文部科学省科学研究費補助金によるがん研究に係る特定領域研究 II「化学療法基盤情報支援班」報告2007
- Author(s)
  矢守隆夫, 上原至雅, 吉田稔, 井本正哉, 清宮啓之, 水上民夫, 川田学, 長田裕之, 松浦正明
- Publisher
  癌と化学療法(印刷中)
- Data Source
  KAKENHI-PROJECT-17012025
[Book] がんにおける脂質代謝、実験医学増刊号「がんと代謝」
- Author(s)
  右田敏郎、馬島哲夫、清宮啓之
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Role of EMT in the DNA damage response, double‐strand break repair pathway choice and its implications in cancer treatment2022
- Author(s)
  Moyret‐Lalle Caroline、Prodhomme Melanie K、Burlet Delphine、Kashiwagi Ayaka、Petrilli Virginie、Puisieux Alain、Seimiya Hiroyuki、Tissier Agnes
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 7 Pages: 2214-2223
- DOI
  10.1111/cas.15389
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-22K19469, KAKENHI-PROJECT-23K24192
[Journal Article] Chemical targeting of G-quadruplexes in telomeres and beyond for molecular cancer therapeutics2021
- Author(s)
  Seimiya Hiroyuki、Nagasawa Kazuo、Shin-ya Kazuo
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 74 Issue: 10 Pages: 617-628
- DOI
  10.1038/s41429-021-00454-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-16H06276
[Journal Article] Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo2021
- Author(s)
  Mashima Tetsuo、Wakatsuki Takeru、Kawata Naomi、Jang Myung-Kyu、Nagamori Akiko、Yoshida Haruka、Nakamura Kenichi、Migita Toshiro、Seimiya Hiroyuki、Yamaguchi Kensei
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15125-15125
- DOI
  10.1038/s41598-021-94584-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-18K08720, KAKENHI-PROJECT-21K07251, KAKENHI-PROJECT-16H06276
[Journal Article] Lamellarin 14, a derivative of marine alkaloids, inhibits the T790M/C797S mutant epidermal growth factor receptor2021
- Author(s)
  Nishiya Naoyuki、Oku Yusuke、Ishikawa Chie、Fukuda Tsutomu、Dan Shingo、Mashima Tetsuo、Ushijima Masaru、Furukawa Yoko、Sasaki Yuka、Otsu Keishi、Sakyo Tomoko、Abe Masanori、Yonezawa Honami、Ishibashi Fumito、Matsuura Masaaki、Tomida Akihiro、Seimiya Hiroyuki、Yamori Takao、Iwao Masatomo、Uehara Yoshimasa
- Journal Title
  
  Cancer Science
  
  Volume: － Issue: 5 Pages: 1963-1974
- DOI
  10.1111/cas.14839
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05715, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-18K09526, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-19H01806, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-19H03526, KAKENHI-PROJECT-21K07251
[Journal Article] G‐quadruplex‐forming nucleic acids interact with splicing factor 3B subunit 2 and suppress innate immune gene expression2021
- Author(s)
  Matsumoto Kyoko、Okamoto Keiji、Okabe Sachiko、Fujii Risa、Ueda Koji、Ohashi Kenichi、Seimiya Hiroyuki
- Journal Title
  
  Genes to Cells
  
  Volume: 26 Issue: 2 Pages: 65-82
- DOI
  10.1111/gtc.12824
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-21K06922
[Journal Article] Novel tankyrase inhibitors suppress TDP-43 aggregate formation2021
- Author(s)
  Tanji Kunikazu、Mori Fumiaki、Shirai Fumiyuki、Fukami Takehiro、Seimiya Hiroyuki、Utsumi Jun、Kakita Akiyoshi、Wakabayashi Koichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 537 Pages: 85-92
- DOI
  10.1016/j.bbrc.2020.12.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02533, KAKENHI-PROJECT-19H03523
[Journal Article] Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α2021
- Author(s)
  Shimizu Takahiro、Takahashi Norihito、Huber Vincent J.、Asawa Yasunobu、Ueda Hiroki、Yoshimori Atsushi、Muramatsu Yukiko、Seimiya Hiroyuki、Kouji Hiroyuki、Nakamura Hiroyuki、Oguri Hiroki
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 30 Pages: 115949-115949
- DOI
  10.1016/j.bmc.2020.115949
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-16H06276
[Journal Article] Pericentromeric noncoding RNA changes DNA binding of CTCF and inflammatory gene expression in senescence and cancer2021
- Author(s)
  Kenichi Miyata, Yoshinori Imai, Satoshi Hori, Mika Nishio, Tze Mun Loo, Ryo Okada, Liying Yang, Tomoyoshi Nakadai, et. al.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 118 Issue: 35
- DOI
  10.1073/pnas.2025647118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07651, KAKENHI-PROJECT-20K21555, KAKENHI-PROJECT-20K16163, KAKENHI-PUBLICLY-20H04789, KAKENHI-PLANNED-20H05940, KAKENHI-PROJECT-18H04034, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-19J00796, KAKENHI-PROJECT-21K19416, KAKENHI-PROJECT-20K16344, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H05686, KAKENHI-PROJECT-19H03507
[Journal Article] Target identification of a macrocyclic hexaoxazole G-quadruplex ligand using post-target-binding visualization2020
- Author(s)
  Yasuda Mizuho、Ma Yue、Okabe Sachiko、Wakabayashi Yuki、Su Dongdong、Chang Young-Tae、Seimiya Hiroyuki、Tera Masayuki、Nagasawa Kazuo
- Journal Title
  
  Chemical Communications
  
  Volume: 56 Issue: 85 Pages: 12905-12908
- DOI
  10.1039/d0cc04957c
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05743, KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-18H04387, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-20K15411, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H02876
[Journal Article] A fully synthetic 6-aza-artemisinin bearing an amphiphilic chain generates aggregates and exhibits anti-cancer activities2020
- Author(s)
  H. Koi, N. Takahashi, Y. Fuchi, T. Umeno, Y. Muramatsu, H. Seimiya, Satoru Karasawa*, and H. Oguri*
- Journal Title
  
  Org. Biomol.Chem
  
  Volume: 18 Issue: 28 Pages: 5339-5343
- DOI
  10.1039/d0ob00919a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07016, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-16H06276
[Journal Article] ALDH1A3-mTOR axis as a therapeutic target for anticancer drug-tolerant persister cells in gastric cancer.2020
- Author(s)
  Kawakami R, Mashima T, Kawata N, Kumagai K, Migita T, Sano T, Mizunuma N, Yamaguchi K, Seimiya H
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 3 Pages: 962-973
- DOI
  10.1111/cas.14316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-19K09136, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-16H06276
[Journal Article] Crossroads of telomere biology and anticancer drug discovery2020
- Author(s)
  Seimiya Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 9 Pages: 3089-3099
- DOI
  10.1111/cas.14540
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-20H04789, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-16H06276
[Journal Article] G-quadruplex in cancer biology and drug discovery.2020
- Author(s)
  Nakanishi C, Seimiya H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: In press Issue: 1 Pages: 45-50
- DOI
  10.1016/j.bbrc.2020.03.178
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-18K19487, KAKENHI-PROJECT-20K21555, KAKENHI-PUBLICLY-20H04789
[Journal Article] Serum IL-8 level as a candidate prognostic marker of response to anti-angiogenic therapy for metastatic colorectal cancer2020
- Author(s)
  Suenaga Mitsukuni、Mashima Tetsuo、Kawata Naomi、Wakatsuki Takeru、Dan Shingo、Seimiya Hiroyuki、Yamaguchi Kensei
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: 36 Issue: 1 Pages: 131-139
- DOI
  10.1007/s00384-020-03748-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-18K07280, KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-21K07251
[Journal Article] Epidermal growth factor receptor mRNA expression: A potential molecular escape mechanism from regorafenib2020
- Author(s)
  Matsusaka Satoshi、Hanna Diana L.、Ning Yan、Yang Dongyun、Cao Shu、Berger Martin D.、Miyamoto Yuji、Suenaga Mitsukuni、Dan Shingo、Mashima Tetsuo、Seimiya Hiroyuki、Zhang Wu、Lenz Heinz‐Josef
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 2 Pages: 441-450
- DOI
  10.1111/cas.14273
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07280, KAKENHI-PROJECT-18K07337, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523
[Journal Article] c-KIT regulates stability of cancer stemness in CD44-positive colorectal cancer cells2020
- Author(s)
  Tomizawa Fumiya、Jang Myung-Kyu、Mashima Tetsuo、Seimiya Hiroyuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 527 Issue: 4 Pages: 1014-1020
- DOI
  10.1016/j.bbrc.2020.05.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-18K07337
[Journal Article] Tankyrase promotes primary precursor miRNA processing to precursor miRNA.2020
- Author(s)
  Mizutani A, Seimiya H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 52 Issue: 4 Pages: 945-951
- DOI
  10.1016/j.bbrc.2019.11.191
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-17K07186, KAKENHI-PROJECT-16H06276
[Journal Article] Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer.2020
- Author(s)
  Shirai F, Mizutani A, Yashiroda Y, Tsumura T, Kano Y, Muramatsu Y, Chikada T, Yuki H, Niwa H, Sato S, Washizuka K, Koda Y, Mazaki Y, Jang MK, Yoshida H, Nagamori A, Okue M, Watanabe T, Kitamura K, Shitara E, Honma T, Umehara T, et al.
- Journal Title
  
  J Med Chem
  
  Volume: 63 Issue: 8 Pages: 4183-4204
- DOI
  10.1021/acs.jmedchem.0c00045
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523
[Journal Article] Tankyrase Inhibitors Target Colorectal Cancer Stem Cells via AXIN-Dependent Downregulation of c-KIT Tyrosine Kinase.2020
- Author(s)
  Jang MK, Mashima T, Seimiya H
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 19 Issue: 3 Pages: 765-776
- DOI
  10.1158/1535-7163.mct-19-0668
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07337, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-16H06276
[Journal Article] In silico chemical screening identifies epidermal growth factor receptor as a therapeutic target of drug-tolerant CD44v9-positive gastric cancer cells.2019
- Author(s)
  Mashima T, Iwasaki R, Kawata N, Kawakami R, Kumagai K, Migita T, Sano T, Yamaguchi K, Seimiya H
- Journal Title
  
  Br J Cancer
  
  Volume: 121 Issue: 10 Pages: 846-856
- DOI
  10.1038/s41416-019-0600-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-19K09136, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-16H06276
[Journal Article] Revisiting Telomere Shortening in Cancer.2019
- Author(s)
  Keiji Okamoto and Hiroyuki Seimiya
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 2 Pages: 107-107
- DOI
  10.3390/cells8020107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07252, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716
[Journal Article] From the wings to the center stage of chromosomes.2019
- Author(s)
  Okamoto K, Seimiya H.
- Journal Title
  
  J Biol Chem
  
  Volume: 294 Issue: 47 Pages: 17723-17724
- DOI
  10.1074/jbc.h119.011587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523, KAKENHI-PROJECT-18K07252, KAKENHI-PROJECT-18K19487
[Journal Article] Meeting report of the 14th Japan Korea joint symposium on cancer and aging research: current status of translational research and approaches to precision medicine2019
- Author(s)
  Sueoka Eisaburo、Watanabe Tatsuro、Mashima Tetsuo、Shirakami Yohei、Komori Atsumasa、Matsuo Keitaro、Yoshikawa Hiroshi Y.、Cho Kyung A、Park Tae Jun、Seimiya Hiroyuki、Kim Eung-Gook、Suganuma Masami、Chung Junho
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 印刷中 Issue: 5 Pages: 1263-1271
- DOI
  10.1007/s00432-019-02887-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09850, KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-18K07968, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523
[Journal Article] A phase I study to determine the maximum tolerated dose of trifluridine/tipiracil and oxaliplatin in patients with refractory metastatic colorectal cancer: LUPIN study2019
- Author(s)
  Suenaga Mitsukuni、Wakatsuki Takeru、Mashima Tetsuo、Ogura Mariko、Ichimura Takashi、Shinozaki Eiji、Nakayama Izuma、Osumi Hiroki、Ota Yumiko、Takahari Daisuke、Chin Keisho、Seimiya Hiroyuki、Yamaguchi Kensei
- Journal Title
  
  Investigational New Drugs
  
  Volume: 印刷中 Issue: 1 Pages: 2567-2575
- DOI
  10.1007/s10637-019-00749-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07280, KAKENHI-PROJECT-18K07337, KAKENHI-PROJECT-16H04716, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-19H03523
[Journal Article] RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.2018
- Author(s)
  Mizutani A, Yashiroda Y, Muramatsu Y, Yoshisa H, Chikada T, Tsumura T, Okue M, Shirai F, Fukami T, Yoshida M, Seimiya H.
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 12 Pages: 4003-4014
- DOI
  10.1111/cas.13805
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07186, KAKENHI-PLANNED-18H05503, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-26221204
[Journal Article] Development of G-quadruplex ligands for selective induction of a parallel-type topology2018
- Author(s)
  Ma Yue、Tsushima Yamato、Sakuma Mai、Sasaki Shogo、Iida Keisuke、Okabe Sachiko、Seimiya Hiroyuki、Hirokawa Takatsugu、Nagasawa Kazuo
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 16 Issue: 40 Pages: 7375-7382
- DOI
  10.1039/c8ob01702f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05349, KAKENHI-PROJECT-16J08216, KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PUBLICLY-18H04387
[Journal Article] Cell-based chemical fingerprinting identifies telomeres and lamin A as modifiers of DNA damage response in cancer cells2018
- Author(s)
  Fujiwara C, Muramatsu Y, Nishii M, Tokunaka K, Tahara H, Ueno M, Yamori T, Sugimoto Y, Seimiya H8
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41598-018-33139-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07502, KAKENHI-PROJECT-18K07302, KAKENHI-PROJECT-18K19487, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-16H06276
[Journal Article] MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs.2018
- Author(s)
  Keiji Okamoto, Tomokazu Ohishi, Mika Kuroiwa, Shun-ichiro Iemura, Tohru Natsume and Hiroyuki Seimiya
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 88 Pages: 35844-35855
- DOI
  10.18632/oncotarget.26312
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07252, KAKENHI-PUBLICLY-18H04633, KAKENHI-PROJECT-16H04716
[Journal Article] Development of G-quadruplex ligand for selective induction of parallel-type topology2018
- Author(s)
  Yue Ma, Yamato Tsushima, Mai Sakuma, Shogo Sasaki, Keisuke Iida, Sachiko Okabe, Hiroyuki Seimiya, Takatsugu Hirokawa, Kazuo Nagasawa
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 16 Pages: 7375-7382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06276
[Journal Article] Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B2018
- Author(s)
  Hatta Tomohisa、Iemura Shun-ichiro、Ohishi Tomokazu、Nakayama Hiroshi、Seimiya Hiroyuki、Yasuda Takao、Iizuka Katsumi、Fukuda Mitsunori、Takeda Jun、Natsume Tohru、Horikawa Yukio
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 16756-16756
- DOI
  10.1038/s41598-018-35204-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00850, KAKENHI-PROJECT-18H02779, KAKENHI-PROJECT-17K19902, KAKENHI-PUBLICLY-18H04633
[Journal Article] APC mutations as a predictive biomarker for sensitivity to tankyrase inhibitors in colorectal cancer.2017
- Author(s)
  Noritaka Tanaka, Tetsuo Mashima, Anna Mizutani, Ayana Sato, Aki Aoyama, Bo Gong, Haruka Yoshida, Yukiko Muramatsu, Kento Nakata, Masaaki Matsuura, Ryohei Katayama, Satoshi Nagayama, Naoya Fujita, Yoshikazu Sugimoto, Hiroyuki Seimiya
- Journal Title
  
  Mol. Cancer Ther.
  
  Volume: 16 Issue: 4 Pages: 739-751
- DOI
  10.1158/1535-7163.mct-16-0578
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02368, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H04716, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-15K14409, KAKENHI-PROJECT-15K14412
[Journal Article] Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion.2017
- Author(s)
  Ohishi T, Yoshida H, Katori M, Migita T, Muramatsu Y, Miyake M, Ishikawa Y, Saiura A, Iemura SI, Natsume T, Seimiya H.
- Journal Title
  
  Cancer Res.
  
  Volume: 77 Issue: 9 Pages: 2328-2338
- DOI
  10.1158/0008-5472.can-16-1846
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04716
[Journal Article] Targeting glioma stem cells in vivo by a G-quadruplex-stabilizing synthetic macrocyclic hexaoxazole2017
- Author(s)
  Nakamura Takahiro、Okabe Sachiko、Yoshida Haruka、Iida Keisuke、Ma Yue、Sasaki Shogo、Yamori Takao、Shin-ya Kazuo、Nakano Ichiro、Nagasawa Kazuo、Seimiya Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 3605-3605
- DOI
  10.1038/s41598-017-03785-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K13094, KAKENHI-PROJECT-26282214, KAKENHI-PROJECT-16J08216, KAKENHI-PROJECT-16K18908, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H04716
[Journal Article] mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer.2017
- Author(s)
  Mashima T, Taneda Y, Jang MK, Mizutani A, Muramatsu Y, Yoshida H, Sato A, Tanaka N, Sugimoto Y, Seimiya H.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 29 Pages: 47902-47915
- DOI
  10.18632/oncotarget.18146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04716
[Journal Article] Epithelial-mesenchymal transition promotes SOX2 and NANOG expression in bladder cancer.2017
- Author(s)
  Migita T, Ueda A, Ohishi T, Hatano M, Seimiya H, Horiguchi SI, Koga F, Shibasaki F.
- Journal Title
  
  Lab Invest.
  
  Volume: 97 Issue: 5 Pages: 567-576
- DOI
  10.1038/labinvest.2017.17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04716
[Journal Article] Report on the use of nonclinical studies in the regulatory evaluation of oncology drugs2016
- Author(s)
  Hayakawa Y, Kawada M, Nishikawa H, Ochiya T, Saya H, Seimiya H, Yao Y, Hayashi M, Kai C, Matsuda A, Naoe T, Ohtsu A, Okazaki T, Saji H, Sata M, Sugimura H, Sugiyama Y, Toi M, Irimura T
- Journal Title
  
  Cancer Sci
  
  Volume: 107(2) Issue: 2 Pages: 189-202
- DOI
  10.1111/cas.12857
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670023, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25293011, KAKENHI-PROJECT-25293184, KAKENHI-PROJECT-24229002, KAKENHI-PROJECT-15K06888, KAKENHI-PROJECT-16K15551, KAKENHI-PROJECT-26290054
[Journal Article] Senescence from glioma stem cell differentiation promotes tumor growth2016
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 470 Issue: 2 Pages: 275-281
- DOI
  10.1016/j.bbrc.2016.01.071
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-14J08396, KAKENHI-PROJECT-25290060
[Journal Article] G-quadruplex ligand-induced DNA damage response coupled with telomere dysfunction and replication stress in glioma stem cells2016
- Author(s)
  Hasegawa D, Okabe S, Okamoto K, Nakano I, Shin-Ya K, Seimiya H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 471 Issue: 1 Pages: 75-81
- DOI
  10.1016/j.bbrc.2016.01.176
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] Comprehensive transcriptomic analysis of molecularly targeted drugs in cancer for target pathway evaluation2015
- Author(s)
  Mashima T, Ushijima M, Matsuura M, Tsukahara S, Kunimasa K, Furuno A, Saito S, Kitamura M, Soma-Nagae T, Seimiya H, Dan S, Yamori T, Tomida A
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 7 Pages: 909-920
- DOI
  10.1111/cas.12682
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25430120, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-26640109, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061
[Journal Article] Predicting risk at the end of the end: Telomere G-tail as a biomarker2015
- Author(s)
  Seimiya H
- Journal Title
  
  EBioMedicine
  
  Volume: 2 Issue: 8 Pages: 802-803
- DOI
  10.1016/j.ebiom.2015.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640109, KAKENHI-PROJECT-25290060
[Journal Article] Design, Synthesis and Evaluation of an L-Dopa-Derived Macrocyclic Hexaoxazole (6OTD) as a G-Quadruplex-Selective Ligand2015
- Author(s)
  Takahiro Nakamura, Yue Ma, Keisuke Iida, Terumi Ohtake, Hiroyuki Seimiya, and Kazuo Nagasawa
- Journal Title
  
  Heterocycles
  
  Volume: 92 Issue: 2 Pages: 305-315
- DOI
  10.3987/com-15-13383
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105013, KAKENHI-PROJECT-13J07907, KAKENHI-PROJECT-26560444, KAKENHI-PROJECT-26860077, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-26282214
[Journal Article] Telomeric repeat-containing RNA/G-quadruplex-forming sequences cause genome-wide alteration of gene expression in human cancer cells in vivo2015
- Author(s)
  Hirashima K, Seimiya H
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 43 Issue: 4 Pages: 2022-2032
- DOI
  10.1093/nar/gkv063
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] Design and Synthesis of a Berberine Dimer: A Fluorescent Ligand with High Affinity towards G-Quadruplexes2015
- Author(s)
  M. Tera, T. Hirokawa, S. Okabe, K. Sugahara, H. Seimiya, K. Shimamoto
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 21 Issue: 41 Pages: 14519-14528
- DOI
  10.1002/chem.201501693
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26750366, KAKENHI-PROJECT-25290060
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.2014
- Author(s)
  Ohishi T, Muramatsu Y, Yoshida H, Seimiya H
- Journal Title
  
  Mol Cell Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290060
[Journal Article] Inhibition of ATP citrate lyase induces triglyceride accumulation with altered fatty acid composition in cancer cells.2014
- Author(s)
  5.Migita T, Okabe S, Ikeda K, Igarashi S, Sugawara S, Tomida A, Soga T, Taguchi R, Seimiya H.
- Journal Title
  
  Int J Cancer.
  
  Volume: 135 Issue: 1 Pages: 37-47
- DOI
  10.1002/ijc.28652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001
[Journal Article] TRIB1 supports prostate tumorigenesis and tumor-propagating cell survival by regulation of endoplasmic reticulum chaperone expression2014
- Author(s)
  Mashima T, Soma-Nagae T, Migita T, Kinoshita R, Iwamoto A, Yuasa T, Yonese J, Ishikawa Y, Seimiya H
- Journal Title
  
  Cancer Res
  
  Volume: 74 Issue: 17 Pages: 4888-4897
- DOI
  10.1158/0008-5472.can-13-3718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-26430177, KAKENHI-PROJECT-221S0001
[Journal Article] Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture2014
- Author(s)
  Shimamoto A, Kagawa H, Zensho K, Sera Y, Kazuki Y, Osaki M, Oshimura M, Ishigaki Y, Hmasaki K, Kodama Y, Yuasa S, Fukuda K, Hirashima K, Seimiya H, Koyama H, Shimizu T, Takemoto M, Yokote K, Goto M, Tahara H.
- Journal Title
  
  PLOS ONE
  
  Volume: 9 Issue: 11 Pages: 1-13
- DOI
  10.1371/journal.pone.0112900
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590902, KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-25670030, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-26670408, KAKENHI-PROJECT-221S0001
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation.2014
- Author(s)
  Ohishi T, Muramatsu Y, Yoshida H, Seimiya H
- Journal Title
  
  Mol Cell Biol
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650639
[Journal Article] TRF1 ensures the centromeric function of Aurora-B and proper chromosome segregation2014
- Author(s)
  Ohishi, T., Muramatsu, Y., Yoshida, H., Seimiya, H.
- Journal Title
  
  Mol Cell Biol
  
  Volume: (in press) Issue: 13 Pages: 2464-2478
- DOI
  10.1128/mcb.00161-14
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25871074, KAKENHI-PROJECT-26640109
[Journal Article] Interaction of long telomeric DNAs with macrocyclic hexaoxazole as a G-quadruplex ligands2013
- Author(s)
  Keisuke Iida, Gen Tsubouchi, Takahiro Nakamura, Satoki Majima, Hiroyuki Seimiya, and Kazuo Nagasawa
- Journal Title
  
  Med. Chem. Commun.
  
  Volume: 4 Issue: 1 Pages: 260-264
- DOI
  10.1039/c2md20234d
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PLANNED-23105013
[Journal Article] Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact2013
- Author(s)
  Migita, T., Okabe, S., Ikeda, K., Igarashi, S., Sugawara, S., Tomida, A., Taguchi, R., Soga, T., Seimiya, H
- Journal Title
  
  Am J Pathol
  
  Volume: 182 Pages: 1800-1810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds.2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104(3) Issue: 3 Pages: 360-368
- DOI
  10.1111/cas.12071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23501319, KAKENHI-PROJECT-23701067, KAKENHI-PROJECT-24240042, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Inhibition of ATP citrate lyase induces an anticancer effect via reactive oxygen species: AMPK as a predictive biomarker for therapeutic impact2013
- Author(s)
  Migita, T., Okabe, S., Ikeda, K., Igarashi, S., Sugawara, S., Tomida, A., Taguchi, R., Soga, T., Seimiya, H.
- Journal Title
  
  Am J Pathol.
  
  Volume: 182 Issue: 5 Pages: 1800-1810
- DOI
  10.1016/j.ajpath.2013.01.048
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134007, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-24619007, KAKENHI-PROJECT-24650626, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25290061, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23117527
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima M, Mashima T, Tomida A, Dan S, Saito S, Furuno A, Tsukahara S, Seimiya H, Yamori T, Matsuura M
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Telomere length influences cancer cell differentiation in vivo.2013
- Author(s)
  Hirashima K, Migita T, Sato S, Muramatsu Y, Ishikawa Y, Seimiya H
- Journal Title
  
  Mol Cell Biol
  
  Volume: 33 Issue: 15 Pages: 2988-2995
- DOI
  10.1128/mcb.00136-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-25290060, KAKENHI-PROJECT-25640071
[Journal Article] Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand2013
- Author(s)
  Iida, K., Majima, S., Nakamura, T., Seimiya, H., Nagasawa, K
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 4328-4341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Evaluation of the interaction between long telomeric DNA and macrocyclic hexaoxazole (6OTD) dimer of a G-quadruplex ligand.2013
- Author(s)
  Iida, K.
- Journal Title
  
  Molecules
  
  Volume: 18 Issue: 4 Pages: 4328-4341
- DOI
  10.3390/molecules18044328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PROJECT-25290060, KAKENHI-PLANNED-23105013, KAKENHI-PUBLICLY-23117527
[Journal Article] Development of a gene expression database and related analysis programs for evaluation of anticancer compounds2013
- Author(s)
  Ushijima, M., Mashima, T., Tomida, A., Dan, S., Saito, S., Furuno, A., Tsukahara, S., Seimiya, H., Yamori, T., Matsuura, M
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Pages: 360-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] JBIR-120: a new growth inhibitor of hormone-refractory prostate cancer cells2012
- Author(s)
  Kawahara, T., Hosoya, T., Tsukamoto, M., Okabe, S., Yamamura, H., Hayakawa, M., Seimiya, H., Takagi, M., Shin-Ya, K
- Journal Title
  
  J Antibiot
  
  Volume: 65 Pages: 373-375
- NAID
  10030955529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.2012
- Author(s)
  Deardorff MA
- Journal Title
  
  Nature
  
  Volume: 489(7415) Issue: 7415 Pages: 313-7
- DOI
  10.1038/nature11316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21681025, KAKENHI-PROJECT-22221009, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23651243, KAKENHI-PROJECT-23710213, KAKENHI-PROJECT-24370076, KAKENHI-PROJECT-24650639, KAKENHI-PLANNED-22125008, KAKENHI-PLANNED-23114003, KAKENHI-PUBLICLY-23117527, KAKENHI-PUBLICLY-24114517
[Journal Article] A Caged Ligand for a Telomeric G-Quadruplex2012
- Author(s)
  T.Nakamura, K.Iida, M.Tera, K.Shin-ya, H.Seimiya, K.Nagasawa
- Journal Title
  
  ChemBioChem
  
  Volume: Vol.13 Issue: 6 Pages: 774-777
- DOI
  10.1002/cbic.201200013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07978, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-23310158, KAKENHI-PROJECT-24650639, KAKENHI-PROJECT-24651258, KAKENHI-PLANNED-23105013, KAKENHI-PUBLICLY-23117527
[Journal Article] et al., HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle2012
- Author(s)
  Deardorff, M.A., Seimiya, H.
- Journal Title
  
  Nature
  
  Volume: 489 Pages: 313-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Telomestatin impairs glioma stem cell survival and growth through the disruption of telomeric G-quadruplex and inhibition of the proto-oncogene, c-Myb2012
- Author(s)
  Miyazaki, T., Pan, Y., Joshi, K., Purohit, D., Hu, B., Demir, H., Mazumder, S., Okabe, S., Yamori, T.,Viapiano, M., Shin-ya, K., Seimiya, H., Nakano, I
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18 Pages: 1268-1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Tankyrase-1 function at telomeres and during mitosis is regulated by Polo-like kinase-1-mediated phosphorylation2012
- Author(s)
  Ha, G. H., Kim, H. S., Go, H., Lee, H., Seimiya, H., Chung, D. H., Lee, C. W
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Pages: 321-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] A caged ligand for a telomeric G-quadruplex2012
- Author(s)
  Nakamura, T., Iida, K., Tera, M., Shin-ya, K., Seimiya, H., Nagasawa, K
- Journal Title
  
  Chembiochem
  
  Volume: 13 Pages: 774-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Telomestatin Impairs Glioma Stem Cell Survival and Growth through the Disruption of Telomeric G-Quadruplex and Inhibition of the Proto-oncogene, c-Myb2011
- Author(s)
  Miyazaki T, Pan Y, Joshi K, Purohit D, Hu B, Demir H, Mazumder S, Okabe S, Yamori T, Viapiano M, Shin-Ya K, Seimiya H, Nakano I
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(5) Issue: 5 Pages: 1268-1280
- DOI
  10.1158/1078-0432.ccr-11-1795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-22300341, KAKENHI-PROJECT-24650639, KAKENHI-PUBLICLY-23117527
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima T, Okabe S, Seimiya H
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima T, Seimiya H
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Data Source
  KAKENHI-PROJECT-23501319
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima, T., Seimiya, H.
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Fission yeast pot1 and recQ helicase are required for efficient chromosome segregation2011
- Author(s)
  Takahashi, K., Imano, R., Kibe, T., Seimiya, H., Muramatsu, Y., Kawabata, N., Tanaka, G., Matsumoto, Y., Hiromoto, T., Koizumi, Y., Nakazawa, N., Yanagida, M., Yukawa, M., Tsuchiya, E., Ueno, M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Pages: 95-506
- NAID
  120004205356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Role of acyl-CoA synthetases in glioma cell survival and its therapeutic implication2011
- Author(s)
  Mashima, T., Seimiya, H
- Journal Title
  
  Tumors of the Central Nervous System
  
  Volume: 1 Pages: 337-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Molecular pharmacological approach reveals potential new strategies to suppress androgen receptor signaling in prostate cancer2011
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H.
- Journal Title
  
  Mol Cell Pharmacol
  
  Volume: 3 Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] Expression of mutant RPA in human cancer cells causes telomere shortening.2010
- Author(s)
  Kobayashi, Y., Sato, K., Kibe, T., Seimiya, H., Nakamura, A., Yukawa, M., Tsuchiya, E., Ueno, M.
- Journal Title
  
  Biosci Biotechnol Biochem 74
  
  Pages: 382-385
- NAID
  10027551727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-Aoverexpression.2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Res 70
  
  Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor.2010
- Author(s)
  Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M.
- Journal Title
  
  Biochem Biophys Res Comma 394
  
  Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells2010
- Author(s)
  Seki, T., Yuasa, S., Oda, M., Egashira, T., Yae, K., Kusumoto, D., Nakata, H., Tohyama, S., Hashimoto, H., Kodaira, M., Okada, Y., Seimiya, H., Fusaki, N., Hasegawa, M., Fukuda, K
- Journal Title
  
  Cell Stem Cell
  
  Volume: 7 Pages: 11-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth2010
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H
- Journal Title
  
  Mol Pharmacol
  
  Volume: 78 Pages: 846-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Tankyrase-1 assembly to large protein complexes blocks its telomeric function2010
- Author(s)
  Hatsugai, K., Ohishi, T., Sugimoto, Y., Seimiya, H
- Journal Title
  
  FEBS Lett
  
  Volume: 584 Pages: 3885-3890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Pharmacological targeting of constitutively active truncated androgen receptor by nigericin and suppression of hormone-refractory prostate cancer cell growth2010
- Author(s)
  Mashima, T., Okabe, S., Seimiya, H.
- Journal Title
  
  Mol Pharmacol
  
  Volume: 78 Pages: 846-854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi T, Hirota T, Tsuruo T, Seimiya H.
- Journal Title
  
  Cancer Res 70
  
  Pages: 2041-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma : IGF-independent antiapoptotic effect via caspase-32010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi, T., Hirota, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Res
  
  Volume: 70 Pages: 2041-2052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650230
[Journal Article] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Ohishi T, Hirota T, Tsuruo T, Seimiya H.
- Journal Title
  
  Cancer Res 70(5)
  
  Pages: 2041-52
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3.2010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y.
- Journal Title
  
  Am J Pathol 176
  
  Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-32010
- Author(s)
  Migita, T., Narita, T., Asaka, R., Miyagi, E., Nagano, H., Nomura, K., Matsuura, M., Satoh, Y., Okumura, S., Nakagawa, K., Seimiya, H., Ishikawa, Y
- Journal Title
  
  Am J Pathol
  
  Volume: 176 Pages: 1756-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole.2010
- Author(s)
  Tera, M., Iida, K., Ikebukuro, K., Seimiya, H., Shin-Ya, K., Nagasawa, K.
- Journal Title
  
  Org Biomol Chem 8
  
  Pages: 2749-2755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Visualization of G-quadruplexes by using a BODIPY-labeled macrocyclic heptaoxazole2010
- Author(s)
  Tera, M., Iida, K., Ikebukuro, K., Seimiya, H., Shin-Ya, K., Nagasawa, K
- Journal Title
  
  Org Biomol Chem
  
  Volume: 8 Pages: 2749-2755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Expression of mutant RPA in human cancer cells causes telomere shortening2010
- Author(s)
  Kobayashi, Y., Sato, K., Kibe, T., Seimiya, H., Nakamura, A., Yukawa, M., Tsuchiya, E., Ueno, M
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 74 Pages: 382-385
- NAID
  10027551727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor2010
- Author(s)
  Yashiroda, Y., Okamoto, R., Hatsugai, K., Takemoto, Y., Goshima, N., Saito, T., Hamamoto, M., Sugimoto, Y., Osada, H., Seimiya, H., Yoshida, M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 394 Pages: 569-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Telomeres and Telomerase in Cancer, Edited by Hiyama K. 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Journal Title
  
  Humana Press
  
  Pages: 281-292
- Data Source
  KAKENHI-PROJECT-20659024
[Journal Article] Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer2009
- Author(s)
  McCabe N, Cerone MA, Ohishi T, Seimiya H, Lord CJ, Ashworth A
- Journal Title
  
  Oncogene 28
  
  Pages: 1465-1470
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2009
- Author(s)
  Mashima, T., Sato, S., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions2009
- Author(s)
  Mashima T, Sato S, Sugimoto Y, Tsuruo T, Seimiya H
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy.2009
- Author(s)
  Mashima, T., Seimiya, H., Tsuruo, T.
- Journal Title
  
  Br J Cancer 100
  
  Pages: 1369-1372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Telomeres and Telomerase in Cancer, Edited by Hiyama K. 「Tankyrase 1, telomere-binding proteins, and inhibitors」2009
- Author(s)
  Seimiya H
- Journal Title
  
  Humana Press
  
  Pages: 281-292
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer.2009
- Author(s)
  McCabe, N., Cerone, M.A., Ohishi, T., Seimiya, H., Lord, C.J., Ashworth, A.
- Journal Title
  
  Oncogene 28
  
  Pages: 1465-1470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy2009
- Author(s)
  Mashima T, Seimiya H, Tsuruo T
- Journal Title
  
  Br J Caner 100
  
  Pages: 1369-1372
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide.2009
- Author(s)
  Mashima, T., Sato, S., Okabe, S., Miyata, S., Matsuura, M., Sugimoto, Y., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Sci 100
  
  Pages: 1556-1562
- NAID
  10027193846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation2008
- Author(s)
  Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-1124
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.2008
- Author(s)
  Muramatsu, Y., Tahara, H., Ono, T., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation.2008
- Author(s)
  Muramatsu, Y. Tahara, H. Ono, T. Tsuruo, T. Seimiya, H.
- Journal Title
  
  Exp Cell Res 314
  
  Pages: 1115-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] ATP citrate lyase : activation and therapeutic implications in non-small cell lung cancer2008
- Author(s)
  Migita T, Narita T, Nomura K, Miyagi E, Inazuka F, Matsuura M, Ushijima M, Mashima T, Seimiya H, Satoh Y, Okumura S, Nakagawa K, Ishikawa Y
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-8554
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.2008
- Author(s)
  Migita, T., Narita, T., Nomura, K., Miyagi, E., Inazuka, F., Matsuura, M., Ushijima, M., Mashima, T., Seimiya, H., Satoh, Y., Okumura, S., Nakagawa, K., Ishikawa, Y.
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-8554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015047
[Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions.2008
- Author(s)
  Mashima, T. Sato, S. Sugimoto, Y. Tsuruo, T. Seimiya, H.
- Journal Title
  
  Oncogene 28
  
  Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] ATP citrate lyase: activation and therapeutic implications in non-small cell lung cancer.2008
- Author(s)
  Migita, T. Narita, T. Nomura, K. Miyagi, E. Inazuka, F. Matsuura, M. Ushijima, M. Mashima, T. Seimiya, H. Satoh, Y. Okumura, S. Nakagawa, K. Ishikawa, Y.
- Journal Title
  
  Cancer Res 68
  
  Pages: 8547-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Cross-species difference in telomeric function of tankyrase 1.2007
- Author(s)
  Muramatsu, Y., Ohishi, T., Sakamoto, M., Tsuruo, T., Seimiya, H.
- Journal Title
  
  Cancer Sci. (in press)
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] hnRNP A3 binds to and protects mammalian telomeric repeats in vitro2007
- Author(s)
  Tanaka E, Fukuda H, Nakashima K, Tsuchiya N, Seimiya H, Nakagama H
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages: 608-614
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Evaluation of tankyrase inhibition in whole cells2007
- Author(s)
  Ohishi T, Tsuruo T, Seimiya H
- Journal Title
  
  Meth Mol Biol 405
  
  Pages: 133-146
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] Cross-species difference in telomeric function of tankyrase 1.2007
- Author(s)
  Muramatsu, Y. Ohishi, T. Sakamoto, M. Tsuruo. T. Seimiya. H.
- Journal Title
  
  Cancer Sci 98
  
  Pages: 850-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Cross-species difference in telomeric function of tankyrase 12007
- Author(s)
  Muramatsu Y, Ohishi T, Sakamoto M, Tsuruo T, Seimiya H
- Journal Title
  
  Cancer Sci 98
  
  Pages: 850-857
- Data Source
  KAKENHI-PROJECT-19370078
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br. J. Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-18015047
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br.J.Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br. J. Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy.2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br J Cancer. 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] The telomeric PARP, tankyrases, as targets for cancer therapy2006
- Author(s)
  Seimiya, H.
- Journal Title
  
  Br.J.Cancer 94
  
  Pages: 341-345
- Data Source
  KAKENHI-PROJECT-17016078
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Call 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-15770114
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17770151
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-16023268
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics2005
- Author(s)
  Seimiya, H.
- Journal Title
  
  Cancer Cell 7
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17016078
[Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics.2005
- Author(s)
  Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T.
- Journal Title
  
  Cancer Cell 7(1)
  
  Pages: 25-37
- Data Source
  KAKENHI-PROJECT-17012025
[Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation.2004
- Author(s)
  Seimiya, H.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 1944-1955
- Data Source
  KAKENHI-PROJECT-15770114
[Journal Article] Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elogation.2004
- Author(s)
  Seimiya, H.
- Journal Title
  
  Mol.Cell.Biol. 24
  
  Pages: 1944-1955
- Data Source
  KAKENHI-PROJECT-16023268
[Journal Article] Telomere length influences cancer cell differentiation in vivo
- Author(s)
  Hirashima,K., Migita,T., Sato, S., Muramatsu, Y., Ishikawa,Y., Seimiya, H
- Journal Title
  
  Mol Cell Biol, in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300341
[Journal Article] Acyl-CoA synthetase as a cancer survival factor : its inhibition enhances the efficacy of etoposide
- Author(s)
  Mashima T, Sato S, Okabe S, Miyata S, Matsuura M, Sugimoto Y, Tsuruo T, Seimiya H
- Journal Title
  
  Cancer Sci (in press)
- NAID
  10027193846
- Data Source
  KAKENHI-PROJECT-19370078
[Patent] がんを治療するための組み合わせ物及び医薬組成物2020
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-008592
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] 新規化合物又はその薬理学的に許容される塩2020
- Inventor(s)
  吉田稔，清宮啓之、他
- Industrial Property Rights Holder
  理化学研究所、がん研究会、株式会社ヤクルト本社
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2021
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Patent] がんを治療するための組み合わせ物及び医薬組成物2020
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-008592
- Filing Date
  2020
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Patent] がんを治療するための組み合わせ物及び医薬組成物2020
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学，公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-008592
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K19487
[Patent] 抗ＶＥＧＦＲ－２抗体医薬品の治療効果を予測するバイオマーカー、検査方法、及び検査キット2019
- Inventor(s)
  馬島哲夫、若槻尊、清宮啓之、山口研成
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03523
[Patent] Novel compound or pharmaceutically acceptable salt thereof2019
- Inventor(s)
  Yoshida M, Seimiya H et al.
- Industrial Property Rights Holder
  理化学研究所、がん研究会、株)ヤクルト本社
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2021
- Overseas
- Data Source
  KAKENHI-PROJECT-19H03523
[Patent] 抗がん剤2019
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー2019
- Inventor(s)
  末永光邦、水沼信之、馬島哲夫、清宮啓之
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03523
[Patent] 新規化合物又はその薬理的に許容される塩2019
- Inventor(s)
  吉田　稔、清宮啓之、他11名
- Industrial Property Rights Holder
  理化学研究所、がん研究会、株)ヤクルト本社
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-19H03523
[Patent] 新規ジヒドロイソキノリノン系化合物又はその薬理学的に許容される塩2019
- Inventor(s)
  吉田稔、八代田陽子、白井文幸、風見純一、清宮啓之
- Industrial Property Rights Holder
  国立研究開発法人理化学研究所、公益財団法人がん研
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-118938
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] 抗がん剤2019
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Patent] 抗がん剤2019
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学，公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Overseas
- Data Source
  KAKENHI-PROJECT-18K19487
[Patent] タンキラーゼ阻害剤感受性を検査する方法、及びその効果を増強する医薬組成物2019
- Inventor(s)
  清宮啓之、藤原千明、杉本芳一
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H04716
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  東京農工大学、がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18K19487
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  東京農工大学、がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Patent] 抗膵がん剤2018
- Inventor(s)
  長澤和夫、松田未沙子、馬悦、清宮啓之
- Industrial Property Rights Holder
  国立大学法人東京農工大学、公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-136579
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] タンキラーゼ阻害剤感受性を検査する方法、及びその効果を増強する医薬組成物2018
- Inventor(s)
  清宮啓之、藤原千明、杉本芳一
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16H04716
[Patent] マルチキナーゼ阻害剤の有効性と安全性を予測する検査方法、検査キット、及びバイオマーカー2015
- Inventor(s)
  末永光邦、水沼信之、馬島哲夫、清宮啓之
- Industrial Property Rights Holder
  公益財団法人がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-251386
- Filing Date
  2015-12-24
- Data Source
  KAKENHI-PROJECT-221S0001
[Patent] 神経膠腫幹細胞を標的とするグアニン四重鎖リガンド2014
- Inventor(s)
  長澤和夫、清宮啓之、飯田圭介、中村貴大
- Industrial Property Rights Holder
  東京農工大学、（公財）がん研究会
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-229221
- Filing Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 制がん性グアニン四重鎖リガンドによるタンパク質生合成の阻害2023
- Author(s)
  岡部幸子、茂木優奈、中西忠也、新家一男、長澤和夫、清宮啓之
- Organizer
  2022年度新学術変革領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム「成果発表会」
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] 制がん性グアニン四重鎖リガンドによるタンパク質生合成の阻害2022
- Author(s)
  岡部幸子，新家一男，長澤和夫，清宮啓之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] がんのテロメアパラドクスを駆動する自然免疫システム2022
- Author(s)
  山本菜摘、岡本啓治、藤原理恵、犬山慶輔、右田敏郎、馬島哲夫、清宮啓之
- Organizer
  文部科学省学術変革領域研究先端モデル動物支援プラットフォーム2022年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] テロメアから始まるがん創薬2022
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科薬科学特論・特講講義セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] 制がん性グアニン四重鎖リガンドの薬力学的バイオマーカーとしてのミトコンドリアRNAの発現変動2022
- Author(s)
  岡部幸子，新家一男，長澤和夫，清宮啓之
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] 制がん剤処理後の残存胃がん細胞における治療抵抗性因子ALDH1A3発現のエピゲノム制御2022
- Author(s)
  李珍、馬島哲夫、清宮啓之
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] がんの特性に基づく創薬の進歩2022
- Author(s)
  清宮啓之
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] シングルセル系譜解析による大腸がん患者由来drug-tolerant persister細胞の追跡2022
- Author(s)
  森野峻, 馬島哲夫, 鈴木穣, 白井文幸, 長山聡, 片山量平, 清宮啓之
- Organizer
  2022年日本バイオインフォマティクス学会年会・第11回生命医薬情報学連合大会
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] テロメアを起点としたがん創薬2022
- Author(s)
  清宮啓之
- Organizer
  レドックスR&D戦略委員会第２回企画シンポジウム「老化制御およびテロメア研究の新基軸」
- Invited
- Data Source
  KAKENHI-PROJECT-22K19469
[Presentation] テロメアを起点としたがん創薬2022
- Author(s)
  清宮啓之
- Organizer
  レドックスR&D戦略委員会第２回企画シンポジウム「老化制御およびテロメア研究の新基軸」
- Invited
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] Single cell lineage analysis for tracing drug-tolerant persister cells in patient-derived colorectal cancer cells：シングルセル系譜解析による大腸がん患者由来drug-tolerant persister細胞の追跡2022
- Author(s)
  森野峻, 馬島哲夫, 鈴木穣, 長山聡, 片山量平, 清宮啓之
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] シングルセル系譜解析による大腸がん患者由来drug-tolerant persister細胞の追跡2022
- Author(s)
  森野峻, 馬島哲夫, 片山量平, 清宮啓之
- Organizer
  第26回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] Advances in drug discovery based on cancer characteristics：がんの特性に基づく創薬の進歩2022
- Author(s)
  清宮啓之
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼを標的としたがん創薬（アカデミア創薬の立場から）2022
- Author(s)
  清宮啓之
- Organizer
  日本がん分子標的治療学会・第5回産学連携に関する検討部会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Significance and challenges in cancer research from the viewpoint of a non-medical doctor：Non-MDの立場から見たがん研究の意義と課題2022
- Author(s)
  清宮啓之
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] Expression of a survival factor, ALDH1A3, is epigenetically regulated in anticancer drug-tolerant gastric cancer cells2022
- Author(s)
  Jin Lee, Tetsuo Mashima, Koshi Kumagai, Kensei Yamaguchi, Hiroyuki Seimiya
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] シングルセル系譜解析による大腸がん患者由来drug-tolerant persister細胞の追跡2022
- Author(s)
  森野峻, 馬島哲夫, 鈴木穣, 白井文幸, 長山聡, 片山量平, 清宮啓之
- Organizer
  シングルセルゲノミクス研究会2022
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] テロメアから始まるがん創薬2022
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科薬科学特論・特講講義セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-23K24192
[Presentation] 染色体の終わりから始まるがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  日本遺伝学会第93回大会，公開市民講座「がんの遺伝的多様性の理解からがんの治療法を考える」
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] テロメアパラドクスの探究と核酸のかたちを標的としたがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  徳島大学歯学部講義セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] テロメアパラドクスの探求と核酸のかたちを標的としたがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  徳島大学歯学部・口腔生命科学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] 制がん性グアニン四重鎖リガンドによるタンパク質生合成の阻害2021
- Author(s)
  岡部幸子，新家一男，長澤和夫，清宮啓之
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] テロメアから始まるがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院薬科学特論・特講セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] 染色体の終わりから始まるがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  日本遺伝学会公開市民講座
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Targeting G-quadruplex nucleic acids for cancer therapeutics2021
- Author(s)
  Seimiya H
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] 染色体の終わりから始まるがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  日本遺伝学会市民公開講座
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Targeting G-quadruplex nucleic acids for cancer therapeutics2021
- Author(s)
  Seimiya, H
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] Innate drug resistance of ALDH1A3-enriched cancer cell subpopulation and its plasticity in gastric cancer2021
- Author(s)
  Tetsuo Mashima, Ryuhei Kawakami, Koshi Kumagai, Takeshi Sano, Kensei Yamaguchi, Hiroyuki Seimiya
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplexを標的としたがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  Takeda Science Urology
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] Targeting G-quadruplex nucleic acids for cancer therapeutics2021
- Author(s)
  Seimiya H
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] テロメアから始まるがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科「薬科学特論・薬科学特講」セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] 患者腫瘍由来大腸がん細胞を用いたタンキラーゼ阻害剤感受性規定候補因子の評価2021
- Author(s)
  陳明じぇ, 馬島哲夫, 村松由起子, 清水裕貴, 長山聡, 片山量平, 清宮啓之
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] G-quadruplexを標的としたがん創薬2021
- Author(s)
  清宮啓之
- Organizer
  Takeda Science Urology
- Invited
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] テロメアから始まるがん創薬2020
- Author(s)
  清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere as the starting point of anticancer drug discovery2020
- Author(s)
  Seimiya H.
- Organizer
  LyonSE&N - ELyT Workshop 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] shRNA スクリーニングによる大腸がん幹細胞の新規治療標的分子経路の探索2020
- Author(s)
  森野峻, 馬島哲夫, 吉田稔, 清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point of anticancer drug discovery2020
- Author(s)
  Seimiya H.
- Organizer
  LyonSE&N - ELyT Workshop 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] c-KITはCD44陽性大腸がん幹細胞の維持に寄与する2020
- Author(s)
  冨澤文弥, 張明奎, 馬島哲夫, 清宮啓之
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] テロメアから始まるがん創薬2020
- Author(s)
  清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] shRNAスクリーニングによる大腸がん幹細胞の新規治療標的分子経路の探索2020
- Author(s)
  森野峻、馬島哲夫、吉田稔、清宮啓之
- Organizer
  日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere as the starting point of anticancer drug discovery2020
- Author(s)
  Seimiya H.
- Organizer
  LyonSE&N - ELyT Workshop 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 受容体型チロシンキナーゼ c-KIT による大腸がん幹細胞性の維持2020
- Author(s)
  冨澤文弥, 張明奎, 馬島哲夫, 清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] 制がん性グアニン四重鎖リガンド耐性がん細胞株の樹立と耐性機構の解明2020
- Author(s)
  岡部幸子, 新家一男, 旦慎吾, 長澤和夫, 清宮啓之
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] 腫瘍形成におけるインターフェロン標的遺伝子ISG15の機能解明2020
- Author(s)
  犬山慶輔、岡本啓治、右田敏郎、藤原理恵、清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度成果発表会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Telomere as the starting point of anticancer drug discovery2020
- Author(s)
  Seimiya H
- Organizer
  LyonSE&N ? ELyT Workshop 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 制がん性グアニン四重鎖リガンド耐性がん細胞株の樹立と耐性機構の解明2020
- Author(s)
  岡部幸子, 新家一男, 旦慎吾, 長澤和夫, 清宮啓之
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] Telomere as the starting point for new cancer molecular medicine2020
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院薬科学特論セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] Telomere as the starting point for new cancer molecular medicine2020
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院薬科学特論セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] テロメアから始まるがん創薬2020
- Author(s)
  清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] 化学シグナルの統合的分子プロファイリングによる四重鎖核酸の機能解明2020
- Author(s)
  清宮啓之
- Organizer
  化学コミュニケーションのフロンティア；第2回領域リトリート
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] 腫瘍形成におけるユビキチン様タンパク質ISG15の機能解明2020
- Author(s)
  犬山慶輔，岡本啓治，藤原理恵，右田敏郎，清宮啓之
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] テロメアから始まるがん創薬2020
- Author(s)
  清宮啓之
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H04789
[Presentation] 患者由来胃がん細胞の不均一性と薬剤抵抗性細胞の治療標的分子2020
- Author(s)
  川上隆兵、馬島哲夫、川田直美、右田敏郎、熊谷厚志、佐野武、水沼信之、山口研成、清宮啓之
- Organizer
  第1回日本癌学会若手の会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point for new cancer molecular medicine2020
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院薬科学特論セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20K21555
[Presentation] 腫瘍形成におけるインターフェロン標的遺伝子ISG15の機能解明2020
- Author(s)
  犬山慶輔、岡本啓治、右田敏郎、藤原理恵、清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度成果発表会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] がんにおけるテロメア短縮のパラドクスを再考する2019
- Author(s)
  岡本啓治、清宮啓之
- Organizer
  第42回日本分子生物学会年会ワークショップ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] EGFR阻害剤による胃がん薬剤抵抗性CD44v発現細胞の増殖抑制とイリノテカンによる治療効果の増強2019
- Author(s)
  馬島哲夫、岩崎里紗、川上隆兵、熊谷厚志、右田敏郎、佐野武、山口研成、清宮啓之
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Hiroyuki Seimiya
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 四重鎖核酸ケモプローブに対する細胞応答の解明とがん創薬への応用2019
- Author(s)
  清宮啓之
- Organizer
  第92回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 分子プロファイリング支援活動のご紹介～小さな分子を起点とした生命科学研究のお手伝い2019
- Author(s)
  清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] 分子プロファイリング支援活動のご紹介～小さな分子を起点とした生命科学研究のお手伝い2019
- Author(s)
  清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Wnt/G4を標的としたがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] テロメア非コードRNAとがん2019
- Author(s)
  清宮啓之
- Organizer
  JARIランチョンセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 制がん性グアニン四重鎖リガンドの新たな作用機序の解明2019
- Author(s)
  岡部幸子、岡本啓治、新家一男、旦慎吾、長澤和夫、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] プロテオーム解析による制がん性グアニン四重鎖リガンドの標的分子の探索2019
- Author(s)
  中西忠也、岡部幸子、岡本啓治、小林美月、新家一男、長澤和夫、清宮啓之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research : Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Tankyrase and G-quadruplex as molecular targets for cancer therapy2019
- Author(s)
  Seimiya H
- Organizer
  第25回日本遺伝子細胞治療学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Visualization of G-quadruplex in Living based on in situ Click reaction2019
- Author(s)
  Mizuho Yasuda, Yue Ma, Sachiko Okabe, Young-Tae Chang, Hiroyuki Seimiya, Kazuo Nagasawa
- Organizer
  The 46th International Symposium on Nucleic Acids Chemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 染色体の末端から始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  徳島大学大学院医歯薬学研究部呼吸器・膠原病内科学分野開講48周年記念会篠原勉先生特任教授就任祝賀会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] テロメア非コードRNAとがん2019
- Author(s)
  清宮啓之
- Organizer
  JARIランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 天然・合成ケミカルツール分子を利用した四重鎖核酸の統合機能解析2019
- Author(s)
  岡部幸子、岡本啓治、新家一男、旦慎吾、長澤和夫、清宮啓之
- Organizer
  化学コミュニケーションのフロンティア第5回公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメア長による遺伝子発現制御と腫瘍形態への影響2019
- Author(s)
  岡本啓治、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] グアニン４重鎖安定化物質の分子プロファイリングとがん創薬への展開2019
- Author(s)
  清宮啓之、新家一男、長澤和夫
- Organizer
  日本農芸化学会2019年度大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の増殖抑制とその分子メカニズム2019
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  The 7th Symposium, RIKEN-Max Planck Joint Research Center
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] グアニン四重鎖リガンドによるミトコンドリア遺伝子の発現制御2019
- Author(s)
  岡部幸子、井上直、村松由起子、新家一男、長澤和夫、清宮啓之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Hiroyuki Seimiya
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Wnt/G4を標的としたがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 四重鎖核酸ケモプローブに対する細胞応答の解明とがん創薬への応用2019
- Author(s)
  清宮啓之
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] テロメアから始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  JSPS「日本におけるケミカルバイオロジーの新展開」に関する産学協力研究委員会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] グアニン四重鎖リガンドによるがん細胞選択的なタンパク質翻訳阻害2019
- Author(s)
  中西忠也、岡部幸子、岡本啓治、小林美月、新家一男、長澤和夫、清宮啓之
- Organizer
  化学コミュニケーションのフロンティア第5回公開シンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] プロテオーム解析による制がん性グアニン四重鎖リガンドの標的分子の探索2019
- Author(s)
  中西忠也、岡部幸子、岡本啓治、小林美月、新家一男、長澤和夫、清宮啓之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Crossroads of telomere biology and cancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  第78回日本癌学会学術総会コアシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Tankyrase and G-quadruplex as molecular targets for cancer therapy2019
- Author(s)
  Seimiya H.
- Organizer
  第25回日本遺伝子細胞治療学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Crossroads of telomere biology and cancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  第78回日本癌学会学術総会コアシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya, H.
- Organizer
  OIST Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] ケミカルツールを利用した四重鎖核酸の統合機能解析とその応用2019
- Author(s)
  清宮啓之
- Organizer
  化学コミュニケーションのフロンティア第6回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] テロメア長による遺伝子発現制御と腫瘍形態への影響2019
- Author(s)
  岡本啓治、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya H
- Organizer
  The 7th Symposium, RIKEN-Max Planck Joint Research Center
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] がんにおけるテロメア短縮のパラドクスを再考する2019
- Author(s)
  岡本啓治、清宮啓之
- Organizer
  第42回日本分子生物学会年会ワークショップ
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 制がん性グアニン四重鎖リガンドの新たな作用機序の解明2019
- Author(s)
  岡部幸子、岡本啓治、新家一男、旦慎吾、長澤和夫、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] タンキラーゼ阻害剤によるAXIN2を介した大腸がん幹細胞のターゲティング2019
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] ケミカルツールを利用した四重鎖核酸の統合機能解析とその応用2019
- Author(s)
  清宮啓之
- Organizer
  化学コミュニケーションのフロンティア第6回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  The 7th Symposium, RIKEN-Max Planck Joint Research Center
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] テロメアから始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  JSPS「日本におけるケミカルバイオロジーの新展開」に関する産学協力研究委員会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Tankyrase and G-quadruplex as molecular targets for cancer therapy2019
- Author(s)
  Seimiya H.
- Organizer
  第25回日本遺伝子細胞治療学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Wnt/G4を標的としたがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医系科学研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] グアニン４重鎖安定化物質の分子プロファイリングとがん創薬への展開2019
- Author(s)
  清宮啓之、新家一男、長澤和夫
- Organizer
  日本農芸化学会2019年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] EGFR阻害剤は胃がん薬剤抵抗性に寄与するCD44v発現細胞の増殖を抑制し、イリノテカンの治療効果を増強する2019
- Author(s)
  馬島哲夫、岩崎里紗、川上隆兵、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] 分子プロファイリング支援活動のご紹介～小さな分子を起点とした生命科学研究のお手伝い2019
- Author(s)
  清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] Crossroads of telomere biology and cancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  第78回日本癌学会学術総会コアシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 生理活性天然物をリードとするグアニン四重鎖を標的とした抗がん剤の創製研究2019
- Author(s)
  馬悦, 中村貴大, 岡部幸子, 新家一男, 清宮啓之, 長澤和夫
- Organizer
  平成30年度先端モデル動物支援プラットフォーム成果発表会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Tankyrase and G-quadruplex as molecular targets for cancer therapy2019
- Author(s)
  Seimiya H.
- Organizer
  第25回日本遺伝子細胞治療学会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] グアニン四重鎖リガンドによるミトコンドリア遺伝子の発現制御2019
- Author(s)
  岡部幸子、井上直、村松由起子、新家一男、長澤和夫、清宮啓之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 四重鎖核酸ケモプローブに対する細胞応答の解明とがん創薬への応用2019
- Author(s)
  清宮啓之
- Organizer
  第92回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] 染色体の末端から始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  徳島大学大学院医歯薬学研究部呼吸器・膠原病内科学分野開講48周年記念会篠原勉先生特任教授就任祝賀会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の増殖抑制とその分子機序2019
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  第23回日本がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Crossroads of telomere biology and cancer drug discovery2019
- Author(s)
  Seimiya H
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 染色体の末端から始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  徳島大学大学院医歯薬学研究部呼吸器・膠原病内科学分野開講48周年記念会篠原勉先生特任教授就任祝賀会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 幹細胞因子による大腸がん幹細胞の維持とその分子機序2019
- Author(s)
  冨澤文弥、張明奎、馬島哲夫、清宮啓之
- Organizer
  文部科学省新学術領域研究学術研究支援基盤形成先端モデル動物支援プラットフォーム 2019年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] Telomere as the starting point of anticancer drug discovery2019
- Author(s)
  Seimiya H.
- Organizer
  The 7th Symposium, RIKEN-Max Planck Joint Research Center
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03523
[Presentation] テロメアから始まるがん創薬2019
- Author(s)
  清宮啓之
- Organizer
  JSPS「日本におけるケミカルバイオロジーの新展開」に関する産学協力研究委員会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] アニリン型側鎖を有する大環状ヘキサオキサゾール化合物の合成とグアニン四重鎖の安定可能2018
- Author(s)
  松田未沙子, 馬悦, 小林美月, 岡部幸子, 広川貴次, 清宮啓之, 長澤和夫
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 染色体の末端から始まるがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学矢上キャンパス特別講義セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex nucleic acids as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya, Kazuo Shin-ya, Kazuo Nagasawa
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] Telomeres as the starting point of cancer biology and drug discovery2018
- Author(s)
  Seimiya, H.
- Organizer
  Nagoya University Cancer Science Course
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 41st Annual Meeting of the Molecular Biology Society of Japan
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] In situ Click反応を基盤とする生細胞中でのG4の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  第36回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex nucleic acid as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 77th Annual Meeting of Japanese Cancer Association (JCA), Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼを標的としたがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  理研シンポジウム第4回 DMP創薬ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアを起点としたがんの本態解明と創薬2018
- Author(s)
  清宮啓之
- Organizer
  第835回千葉県がんセンター研究所集談会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新規タンキラーゼ阻害剤RK-287107は非臨床モデルで大腸がんを抑制する2018
- Author(s)
  水谷アンナ、村松由起子、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] New mode-of-action of a telomerase inhibitor MST-312 and modifiers of its anticancer efficacy2018
- Author(s)
  藤原千明、村松由起子、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] shRNAスクリーニングによるタンキラーゼ合成致死因子の同定2018
- Author(s)
  藤原千明、杉本芳一、清宮啓之
- Organizer
  平成30年度新学術領域研究・学術研究支援基盤形成・先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Telomere as the starting point of anticancer drug discovery2018
- Author(s)
  Seimiya, H.
- Organizer
  RIKEN IMS Cancer Immunology Seminar Series
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Seimiya, H.
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の標的化とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 大環状ヘキサオキサゾール誘導体を用いた生細胞内でのグアニン四重鎖構造の可視化2018
- Author(s)
  安田瑞穂, 馬悦, 岡部幸子, 清宮啓之, Young-Tae Chang, 長澤和夫
- Organizer
  第13回化学生態学研究会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Targeting glioma stem cells by pharmacological stabilization of G-quadruplexes2018
- Author(s)
  Sachiko Okabe, Takahiro Nakamura, Daiki Hasegawa, Reina Kojima, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Kazuo Nagasawa, Hiroyuki Seimiya
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] テロメアから始まるがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  お茶の水がん学アカデミア第145回集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Targeting colorectal cancer stem-like CD44-positive cells by tankyrase inhibitors2018
- Author(s)
  Tetsuo Mahima, Myung-kyu Jang, Hiroyuki Seimiya
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメア関連因子を標的としたがん創薬2018
- Author(s)
  清宮啓之
- Organizer
  愛知県がんセンター研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Targeting colorectal cancer stem cells by tankyrase inhibition2018
- Author(s)
  Tetsuo Mashima, Myung-Kyu Jang, Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex nucleic acids as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya, Kazuo Shin-ya, Kazuo Nagasawa
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04633
[Presentation] New mode-of-action of a telomerase inhibitor MST-312 and modifiers of its anticancer efficacy2018
- Author(s)
  藤原千明、村松由起子、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 新規タンキラーゼ阻害剤RK-287107は非臨床モデルで大腸がんを抑制する2018
- Author(s)
  水谷アンナ、村松由起子、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex as a molecular target for cancer therapy2018
- Author(s)
  Hiroyuki Seimiya
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の増殖抑制とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、吉田喜香、清宮啓之
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアの長さによって発現変動する遺伝子群が腫瘍形態に及ぼす影響2018
- Author(s)
  藤原理恵、岡本啓治、吉田喜香、右田敏郎、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度成果発表会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Identification of potential biomarkers for sensitivity to tankyrase inhibitors in patient-derived colorectal cancer2018
- Author(s)
  Oishi T, Mashima T, Sato A, Yoshida H, Aoyama A, Gong B, Katayama R, Nagayama S, Fujita N, and Seimiya H.
- Organizer
  The 14th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] Targeting glioma stem cells by pharmacological stabilization of G-quadruplexes2018
- Author(s)
  Sachiko Okabe, Takahiro Nakamura, Daiki Hasegawa, Reina Kojima, Keiji Okamoto, Ichiro Nakano, Kazuo Shin-ya, Kazuo Nagasawa, Hiroyuki Seimiya
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19487
[Presentation] 大腸がん幹細胞を標的とするタンキラーゼ阻害剤とその作用メカニズム2018
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  平成30年度新学術領域研究・学術研究支援基盤形成・先端モデル動物支援プラットフォーム・若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の増殖抑制と抗がん剤との併用効果2017
- Author(s)
  張明奎，馬島哲夫，吉田喜香，清宮啓之
- Organizer
  第61回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメラーゼ阻害剤MST-312の即時的制がん効果を規定する因子2017
- Author(s)
  藤原千明、村松由起子、水谷アンナ、矢守隆夫、杉本芳一、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 大腸がん幹細胞様CD44陽性細胞へのタンキラーゼ阻害剤の増殖抑制作用と治療アプローチ2017
- Author(s)
  馬島哲夫，張明奎，吉田喜香，村松由起子，清宮啓之
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 分子プロファイリング支援活動のご紹介2017
- Author(s)
  清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] テロメア動態に基づくがんの本態解明と創薬2017
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学 1st Urology Conference at Shinanomachi
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 鶴尾隆賞受賞講演 : テロメアを起点としたがんの本態解明と分子標的治療薬の開発2017
- Author(s)
  清宮啓之
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 大腸がん細胞株のタンキラーゼ阻害剤感受性を予測するAPC変異2017
- Author(s)
  田中伯享，馬島哲夫，旦慎吾，杉本芳一，清宮啓之
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] G-quadruplex in cancer biology and drug development2017
- Author(s)
  Hiroyuki Seimiya
- Organizer
  Tokyo Medical University, Institute of Medical Science, 1st International Symposium "Role of Aging and Cancer”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアを起点としたがんの本態解明と分子標的治療薬の開発2017
- Author(s)
  清宮啓之
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアから始まるがん分子創薬2017
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医歯薬保健学研究科セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] テロメアを起点としたがんの本態解明と分子標的治療薬の開発2017
- Author(s)
  清宮啓之
- Organizer
  京都大学学際融合教育推進センター生理化学研究ユニット第7回シンポジウム“Chemistryで紐解くPhysiology”
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] タンキラーゼ阻害剤による大腸がん幹細胞の標的化と抗がん剤の効果増強2017
- Author(s)
  張明奎，馬島哲夫，清宮啓之
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] 大腸がん幹細胞を標的とする化合物の探索と細胞傷害性抗がん剤との併用効果2017
- Author(s)
  張明奎、馬島哲夫、清宮啓之
- Organizer
  先端モデル動物支援プラットフォーム平成29年度若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] G-quadruplex in cancer biology and drug dcvelopment2017
- Author(s)
  清宮啓之
- Organizer
  Tokyo Modical University, Instituto of Medical Science, Ist International Symposium "Role of Aging and Cancer"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Telomere maintenance system as an anticancer therapeutic target2016
- Author(s)
  清宮啓之
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] がん創薬にむけたテロメア研究の進歩2016
- Author(s)
  清宮啓之
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2016-07-28
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] PARPファミリー酵素を標的とする抗がん剤の開発2016
- Author(s)
  清宮啓之
- Organizer
  CBI学会2016年大会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2016-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-16H04716
[Presentation] New mode-of-action of anticancer effects of G-quadruplex ligands2016
- Author(s)
  Reina Kojima, Keiji Okamoto, Sachiko Okabe, Takahiro Nakamura, Kazuo Nagasawa, and Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] PARPファミリー酵素を標的とする抗がん剤の開発2016
- Author(s)
  清宮啓之
- Organizer
  理研創薬･医療技術基盤プログラム第３回ワークショップ
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] TERRA G-quadruplex as a potential modifier of cancer behavior2016
- Author(s)
  Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] A preferential growth inhibitory activity of a G-quadruplex ligand against glioma stem cells2016
- Author(s)
  Takahiro Nakamura, Sachiko Okabe, Keisuke Iida, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa and Hiroyuki Seimiya
- Organizer
  The 13th Korea-Japan Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Jeju, Korea
- Year and Date
  2016-02-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TNKS1BP1 regulates the actin filament dynamics and cancer cell invasion2016
- Author(s)
  Yoshida H, Ohishi T, Muramatsu Y, Seimiya H
- Organizer
  10th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] Senescence from cancer stem cell differentiation promotes tumor growth in glioblastoma2016
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Organizer
  The 10th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex: a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2015
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学理工学部セミナー
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2015-10-28
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex, a potential modifier of cancer behavior and a target for the therapeutic intervention2015
- Author(s)
  清宮啓之
- Organizer
  国際高等研究所研究プロジェクト「クロマチン・デコーディング」2014年度第1回研究会
- Place of Presentation
  国際高等研究所（京都府・木津川市）
- Year and Date
  2015-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2015
- Author(s)
  清宮啓之
- Organizer
  日本癌学会シンポジウム/共同利用･共同研究拠点シンポジウム「がん幹細胞･微小環境･分子標的～がん進展制御への挑戦」
- Place of Presentation
  石川県立音楽堂交流ホール（石川県・金沢市）
- Year and Date
  2015-01-22
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] がん分子標的創薬をめぐる最近の話題2015
- Author(s)
  清宮啓之
- Organizer
  第74回日本癌学会学術総会モーニングレクチャー
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] タンキラーゼ結合タンパク質TAB182はアクチン細胞骨格の再構成を介してがん細胞の浸潤を調節する2015
- Author(s)
  大石智一、吉田喜香、村松由起子、清宮啓之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] TERRA G-quadruplex as a potential modifier of the genome-wide gene expression and cancer behavior in vivo2015
- Author(s)
  Hiroyuki Seimiya
- Organizer
  5th International Meeting on Quadruplex Nucleic Acids
- Place of Presentation
  Bordeaux、France
- Year and Date
  2015-05-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Senescence derived from glioma stem cell differentiation and its implication in the tumor progression2015
- Author(s)
  Rie Ouchi, Sachiko Okabe, Toshiro Migita, Ichiro Nakano, Hiroyuki Seimiya
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] ポリADP-リボシル化酵素タンキラーゼの多元的機能と創薬応用2015
- Author(s)
  清宮啓之
- Organizer
  BMB2015（第38回日本分子生物学会年会、第88回日本生化学会大会合同大会）
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] Glioma stem cell-selective antitumor effect of a novel G-quadruplex ligand2015
- Author(s)
  Takahiro Nakamura, Sachiko Okabe, Keisuke Iida, Takao Yamori, Kazuo Shin-ya, Ichiro Nakano, Kazuo Nagasawa and Hiroyuki Seimiya
- Organizer
  The 20th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Daiba, Tokyo
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] タンキラーゼ結合蛋白質TAB182による細胞浸潤能の制御2015
- Author(s)
  大石智一、村松由起子、清宮啓之
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  愛知県松山市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] グアニン４重鎖を標的としたがん創薬2015
- Author(s)
  清宮啓之
- Organizer
  愛媛大学医学部分子病態医学セミナー
- Place of Presentation
  愛媛県東温市
- Year and Date
  2015-04-03
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Growth inhibition mechanisms for a telomestatin derivative against glioma stem cells2015
- Author(s)
  中村貴大、岡部幸子、飯田圭介、新家一男、長澤和夫、清宮啓之
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] G-quadruplex: a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2015
- Author(s)
  Hiroyuki Seimiya
- Organizer
  Developmental Therapeutics Branch, National Cancer Institute, Special DTB Seminar
- Place of Presentation
  Bethesda, USA
- Year and Date
  2015-04-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 神経膠腫幹細胞に対するグアニン四重鎖リガンドの制がん作用機序2015
- Author(s)
  長谷川大記、岡部幸子、中野伊知郎、新家一男、清宮啓之
- Organizer
  BMB2015
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] テロメスタチン誘導体による神経膠腫幹細胞の増殖抑制メカニズム2015
- Author(s)
  中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、長澤和夫、清宮啓之
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  愛媛県松山市
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] テロメア蛋白質TRF1による染色体分配制御2014
- Author(s)
  清宮啓之、大石智一
- Organizer
  第73回日本癌学会学術総会シンポジウム
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] G-quadruplex, a potential modifier of cancer behavior and a therapeutic target for glioma stem cells2014
- Author(s)
  Seimiya H
- Organizer
  The 4th Japan-France Cancer Workshop
- Place of Presentation
  関西セミナーハウス（京都府・京都市）
- Year and Date
  2014-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Telomeres and G-quadruplexes as targets for cancer therapy2014
- Author(s)
  Seimiya, H.
- Organizer
  Kangwon National University Research Seminar
- Place of Presentation
  Gangwon-Do, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] PARP阻害剤をめぐる最近の話題(Year in Review)2014
- Author(s)
  清宮啓之
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ(宮城県・仙台市)
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Telomeres and G-quadruplexes as targets for cancer therapy.2014
- Author(s)
  Seimiya, H.
- Organizer
  Kangwon National University Research Seminar
- Place of Presentation
  Gangwon-Do, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] 再燃性前立腺がんにおける短鎖型アンドロゲン受容体の役割とその制御物質2014
- Author(s)
  岡部幸子、馬島哲夫、清宮啓之
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] G-quadruplex as a therapeutic target for glioma stem cells2014
- Author(s)
  Seimiya H
- Organizer
  The 19th Japan-Korea Cancer Research Workshop
- Place of Presentation
  Jeju (Korea)
- Year and Date
  2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] PARP阻害剤をめぐる最近の話題2014
- Author(s)
  清宮啓之
- Organizer
  第18回日本がん分子標的治療学会学術集会 Year in Review
- Place of Presentation
  仙台市情報・産業プラザ（宮城県・仙台市）
- Year and Date
  2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-26640109
[Presentation] 神経膠腫幹細胞に対するテロメスタチン誘導体の選択的な抗腫瘍効果2014
- Author(s)
  中村貴大、岡部幸子、飯田圭介、矢守隆夫、新家一男、中野伊知郎、長澤和夫、清宮啓之
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] G4リガンドによるがん幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第47回愛媛大学分子病態医学セミナー
- Place of Presentation
  松山
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  日本癌学会学術総会（モーニングレクチャー）
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Telomere length influences cancer cell differentiation in vivo2013
- Author(s)
  Seimiya, H
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TRF1 ensures proper chromosome segregation in mitosis2013
- Author(s)
  Seimiya, H., Ohishi, T., Muramatsu, Y.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2013-05-02
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeted therapy of glioma stem cells with G-quadruplex ligands.2013
- Author(s)
  Seimiya, H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Telomere length influences cancer cell differentiation in vivo2013
- Author(s)
  Seimiya H.
- Organizer
  The 3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Year and Date
  2013-11-20
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] テロメア配列はヒトがん細胞の遺伝子発現を制御する2013
- Author(s)
  平島匡太郎、清宮啓之
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeted therapy of glioma stem cells with G-quadruplex ligands2013
- Author(s)
  Seimiya, H
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会モーニングレクチャー
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] 抗がん剤探索アプローチの変遷と最近の話題2013
- Author(s)
  清宮啓之
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TRF1 ensures proper chromosome segregation in mitosis.2013
- Author(s)
  Seimiya, H
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H
- Organizer
  第9回日米合同癌会議
- Place of Presentation
  (Ninth AACR-JCA Joint Conference, Breakthroughs in Basic and Translational Cancer Research) (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  (東京)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] グアニン４重鎖リガンドによる神経膠腫幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25290060
[Presentation] TRF1 ensures proper chromosome segregation in mitosis.2013
- Author(s)
  Seimiya, H
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Year and Date
  2013-02-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2013
- Author(s)
  Seimiya, H.
- Organizer
  9th AACR-JCA Joint Conference: Breakthroughs in Basic and Translational Cancer Research
- Place of Presentation
  Hawaii, USA
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] RNAiスクリーニングおよび遺伝子発現データを用いた統合的解析による前立腺がん幹細胞生存因子の同定2013
- Author(s)
  馬島哲夫、湯浅健、清宮啓之
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23501319
[Presentation] 遺伝子発現解析とRNAi探索による前立腺がん腫瘍源細胞生存因子の同定2013
- Author(s)
  馬島哲夫、清宮啓之
- Organizer
  第７２回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23501319
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2013
- Author(s)
  Seimiya, H.
- Organizer
  1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Telomere length influences cancer cell differentiation in vivo.2013
- Author(s)
  Seimiya, H
- Organizer
  3rd GDRI French Japanese Cancer Meeting
- Place of Presentation
  Toulouse, France
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] G4リガンドによるがん幹細胞のターゲティング2013
- Author(s)
  清宮啓之
- Organizer
  第47回愛媛大学分子病態医学セミナー
- Place of Presentation
  松山
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメア長が腫瘍内遺伝子発現に及ぼす影響2012
- Author(s)
  平島匡太郎、右田敏郎、佐藤重男、石川雄一、清宮啓之
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H
- Organizer
  第71回日本癌学会学術総会International Session(招待講演)
- Place of Presentation
  (札幌)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  (L'Isle sur la Sorgue, France)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research(招待講演)
- Place of Presentation
  (Gyeongju, Korea)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん研究基礎セミナー「新薬の原石をもとめて〜抗がん剤・化合物スクリーニング〜」2012
- Author(s)
  清宮啓之
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H., Ohishi, T., Muramatsu Y.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L'Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] がん研究基礎セミナー「新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～」2012
- Author(s)
  清宮啓之
- Organizer
  2012年度文部科学省科学研究費補助金新学術領域研究「がん研究分野の特性等を踏まえた支援活動」がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼによる細胞制御と阻害剤開発2012
- Author(s)
  清宮啓之
- Organizer
  慶應義塾大学先端医科学研究所セミナー(招待講演)
- Place of Presentation
  (東京)
- Year and Date
  2012-10-11
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 2nd Japanese-French Cancer Workshop
- Place of Presentation
  徳島
- Year and Date
  2012-11-28
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Invited
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] 新薬の原石をもとめて　～抗がん剤・化合物スクリーニング～2012
- Author(s)
  Seimiya, H.
- Organizer
  平成24年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科
- Year and Date
  2012-09-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Targeting glioma stem cells by G-quadruplex ligands2012
- Author(s)
  Seimiya, H
- Organizer
  2nd Japanese-French Cancer Workshop(招待講演)
- Place of Presentation
  (鳴門)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein2012
- Author(s)
  Seimiya, H.
- Organizer
  The 11th Korea-Japan-Germany Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  Gyeongju, Korea
- Year and Date
  2012-07-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] TRF1 regulates the microtubule-kinetochore attachment and contributes to proper chromosome segregation2012
- Author(s)
  Seimiya, H.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  L’Isle sur la Sorgue, France
- Data Source
  KAKENHI-PROJECT-24650639
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会
- Place of Presentation
  学士会館(東京都)(招待講演)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  Seimiya, H
- Organizer
  ニース大学招待セミナー(招待講演)
- Place of Presentation
  (フランス・ニース)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー
- Place of Presentation
  愛媛大学(愛媛県)(招待講演)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  清宮啓之
- Organizer
  ニース大学招待セミナー
- Place of Presentation
  ニース大学(フランス・ニース)(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] 脂質代謝酵素を標的とした乳癌、前立腺癌の治療とその分子機構2011
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第11回関東ホルモンと癌研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  Seimiya, H
- Organizer
  日仏がん研究ワークショップ(招待講演)
- Place of Presentation
  (フランス・モンペリエ)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー
- Place of Presentation
  愛媛大学(愛媛県)(招待講演)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会(招待講演)
- Place of Presentation
  (東京)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん治療応用を目指したテロメア研究の現況2011
- Author(s)
  清宮啓之
- Organizer
  医薬ライセンシング協会第236回月例会
- Place of Presentation
  学士会館(東京都)(招待講演)
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Telomere fingerprinting for drug sensitivity studies and cancer cell biology2011
- Author(s)
  清宮啓之
- Organizer
  ニース大学招待セミナー
- Place of Presentation
  ニース大学(フランス・ニース)(招待講演)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] ナイジェリシンによる恒常活性化型アンドロゲン受容体の抑制はホルモン再燃性前立腺がん細胞増殖を阻害する2011
- Author(s)
  馬島哲夫、岡部幸子、清宮啓之
- Organizer
  第11回関東ホルモンと癌研究会
- Place of Presentation
  東京
- Year and Date
  2011-01-29
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] テロメアを起点とした創薬シーズ開発と新たながん生物学研究への展開2011
- Author(s)
  清宮啓之
- Organizer
  愛媛大学第4回分子病態医学セミナー(招待講演)
- Place of Presentation
  (松山)
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  清宮啓之
- Organizer
  日仏がん研究ワークショップ
- Place of Presentation
  Mercure Montpellier Centre(フランス・モンペリエ)(招待講演)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PUBLICLY-23117527
[Presentation] Regulation of chromosome segregation by a telomeric protein TRF12011
- Author(s)
  清宮啓之
- Organizer
  日仏がん研究ワークショップ
- Place of Presentation
  Mercure Montpellier Centre(フランス・モンペリエ)(招待講演)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」(招待講演)
- Place of Presentation
  (京都)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がんとは何でしょう?2011
- Author(s)
  清宮啓之
- Organizer
  新学術領域研究「がん研究分野の特性等を踏まえた支援活動」青少年・市民公開講座～いま知っておきたい「がん」のこと～
- Place of Presentation
  福島県立医科大学(福島県)(招待講演)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Involvement of constitutively active truncated androgen receptor(tAR) in hormone-refractory prostate cancer growth and the tAR inhibition by nigericin2011
- Author(s)
  Mashima T., Okabe S., Seimiya H.
- Organizer
  第10回日韓がん老化合同シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の新たな分子機能2011
- Author(s)
  清宮啓之
- Organizer
  第84回日本生化学会大会シンポジウム「ADP-リボシル化によるシグナル伝達制御」
- Place of Presentation
  国立京都国際会館(京都府)(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Inhibition of ATP citrate lyase mediates anticancer effects via reactive oxygen species and triglyceride accumulation2011
- Author(s)
  右田敏郎、岡部幸子、池田和貴、曽我朋義、田口良、清宮啓之
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] テロメア制御因子の新たな機能と阻害剤探索2010
- Author(s)
  清宮啓之
- Organizer
  広島大学大学院医歯薬学総合研究科セミナー
- Place of Presentation
  広島
- Year and Date
  2010-01-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  Seimiya H
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Texas, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] がん治療応用をめざしたテロメア研究の新展開2010
- Author(s)
  清宮啓之
- Organizer
  東京大学医科学研究所学友会セミナー・GCOE特別セミナー
- Place of Presentation
  東京
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression.2010
- Author(s)
  Seimiya, H., Ohishi, H., Hirota, T., Tsuruo, T.
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] 細胞分裂の異常を媒介するテロメア蛋白質2010
- Author(s)
  清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-Aoverexpression2010
- Author(s)
  清宮啓之
- Organizer
  AACR Special Conference on the Role of Telomer ase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-17
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] 細胞分裂の異常を媒介するテロメア蛋白質2010
- Author(s)
  清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  (神戸)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん細胞の増殖・生存における脂質代謝酵素の役割2010
- Author(s)
  岡部幸子、右田敏郎、馬島哲夫、清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] がん分子標的治療探索とトランスレーショナルリサーチへの展開2010
- Author(s)
  清宮啓之
- Organizer
  中国・四国広域がんプロ養成コンソーシアム・徳島大学大学院セミナー
- Place of Presentation
  徳島
- Year and Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20659024
[Presentation] 脂質代謝酵素の阻害による制がん効果とその分子メカニズム2010
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第14回日本がん分子標的治療学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] Development of telomerase inhibitors and their application to anticancer therapeutics2010
- Author(s)
  Seimiya, H
- Organizer
  Pacifichem 2010
- Place of Presentation
  (Hawaii, USA)
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] Telomere fingerprinting for prediction of anticancer drug sensitivities2010
- Author(s)
  清宮啓之
- Organizer
  AACR/JCA Joint Conference : Cancer Genomics, Epigenomics and the Development of Novel Therapeutics
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-02-09
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] がん治療応用をめざしたテロメア研究の新展開2010
- Author(s)
  清宮啓之
- Organizer
  東京大学医科学研究所・学友会セミナー・GCOE特別セミナー
- Place of Presentation
  (東京)
- Year and Date
  2010-07-26
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] がん分子標的治療探索とトランスレーショナルリサーチへの展開2010
- Author(s)
  清宮啓之
- Organizer
  中国・四国広域がんプロ養成コンソーシアム・徳島大学大学院セミナー
- Place of Presentation
  徳島
- Year and Date
  2010-02-03
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] 脂質代謝酵素の阻害によるがん細胞死とその分子機構2010
- Author(s)
  右田敏郎、岡部幸子、清宮啓之
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会・ワークショップ
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22650230
[Presentation] Development of telomerase inhibitors and their application to anticancer therapeutics2010
- Author(s)
  Seimiya, H.
- Organizer
  Pacifichem 2010
- Place of Presentation
  Hawaii, USA
- Year and Date
  2010-12-15
- Data Source
  KAKENHI-PROJECT-22300341
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression2010
- Author(s)
  清宮啓之
- Organizer
  AACR Special Conference on the Role of Telomerase and Telomeres in Cancer Research
- Place of Presentation
  Fort Worth, USA
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities2009
- Author(s)
  Seimiya, H.
- Organizer
  Japanese-German Cancer Workshop
- Place of Presentation
  Hamburg, Germany
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere maintenance systems as anticancer targets.2009
- Author(s)
  Seimiya, H.
- Organizer
  The 14th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies.2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research.
- Place of Presentation
  韓国, Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] テロメアを標的としたがん治療2009
- Author(s)
  清宮啓之
- Organizer
  第2回富山ライフサイエンスシンポジウム～がんの基礎研究と臨床研究のかけわたし～
- Place of Presentation
  富山
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメアの構造的多様性を起点とした薬剤反応性研究2009
- Author(s)
  清宮啓之
- Organizer
  理化学研究所ケミカルバイオロジー研究領域勉強会
- Place of Presentation
  和光
- Year and Date
  2009-04-22
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  Seimiya, H.
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research.
- Place of Presentation
  Damyang, Korea
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア・老化関連分子を標的とした新規がん化学療法の開発2009
- Author(s)
  清宮啓之
- Organizer
  第1回佐賀大学先端研究センター研究推進部門セミナー「がん分子標的療法の新展開」
- Place of Presentation
  佐賀
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] ポリ(ADP-リボシル)化酵素タンキラーゼ1の自己多量体化によるテロメア機能の調節2009
- Author(s)
  初谷香織、大石智一、杉本芳一、鶴尾隆、清宮啓之
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere maintenance systems as anticancer targets2009
- Author(s)
  清宮啓之
- Organizer
  The 14th Japanese Foundation for Cancer Research-International Symposium on Cancer Chemotherapy
- Place of Presentation
  Tokyo, Japan
- Year and Date
  2009-12-02
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities2009
- Author(s)
  清宮啓之
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2009-04-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Reseach
- Place of Presentation
  韓国・Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere Fingerprint Database の構築と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting for global prediction of anticancer drug sensitivities.2009
- Author(s)
  Seimiya, H., Muramatsu, Y., Tokunaga, S., Tahara, H., Ueno, M., Yamori, T., Tsuruo, T.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & Telomerase.
- Place of Presentation
  Cold Spring Harbor, USA
- Year and Date
  2009-04-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere Fingerprint Databaseの構築と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之、村松由起子、田原栄俊、矢守隆夫、鶴尾隆
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-25
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  清宮啓之
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research
- Place of Presentation
  韓国・Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア・老化関連分子を標的とした新規がん化学療法の開発2009
- Author(s)
  清宮啓之
- Organizer
  第1回佐賀大学先端研究センター研究推進部門セミナー「がん分子標的療法の新展開」
- Place of Presentation
  佐賀
- Year and Date
  2009-02-27
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用・岩手医科大学2009
- Author(s)
  清宮啓之
- Organizer
  化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア動態制御ネットワークの解明と薬剤反応性研究への応用2009
- Author(s)
  清宮啓之
- Organizer
  岩手医科大学・化学療法基盤情報支援班共催シンポジウム「抗がん剤創薬の新たな展開」
- Place of Presentation
  岩手
- Year and Date
  2009-01-16
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Telomere fingerprinting and its application to drug sensitivity studies2009
- Author(s)
  Seimiya H
- Organizer
  The 9th Korea-Japan Symposium on Cancer and Ageing Research
- Place of Presentation
  韓国Damyang
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] TRF1 mediates mitotic abnormalities induced by Aurora A overexpression2008
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities2008
- Author(s)
  Seimiya H, Ohishi T, Tsuruo T
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイスVillars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acyl-CoA synthetase as a survival factor of cancer : its inhibition enhances the efficacy of cancer chemotherapy2008
- Author(s)
  清宮啓之
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20659024
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities2008
- Author(s)
  清宮啓之
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイス・Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  清宮啓之
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  スイス・Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Construction of the Telomere Fingerprint Database, a novel platform for telomere dynamics and drug sensitivity studies.2008
- Author(s)
  清宮啓之、村松由起子、田原栄俊、上野勝、矢守隆夫、鶴尾隆
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  Seimiya, H., Ohishi, T., Tsuruo, T.
- Organizer
  EMBO Conference on Telomeres and the DNA Damage Response
- Place of Presentation
  Villars-sur-Ollon, Switzerland
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] Construction of the Telomere Fingerprint Database, a novel platform for telomere dynamics and drug sensitivity studies2008
- Author(s)
  清宮啓之、村松由起子、田原栄俊、上野勝、矢守隆夫、鶴尾隆
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses oncogene-induced mitotic abnormalities.2008
- Author(s)
  清宮啓之, 大石智一, 鶴屋隆
- Organizer
  欧州EMBOカンファレンス「Telomeres and the DNA Damage Response」
- Place of Presentation
  Switzerland, Villars-sur-Ollon
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] 細胞分裂におけるテロメア結合蛋白質の新たな機能2008
- Author(s)
  清宮啓之
- Organizer
  第26回日本ヒト細胞学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-20015047
[Presentation] テロメア伸長がもたらすがん細胞の遺伝子発現変化2008
- Author(s)
  平島匡太郎、鶴尾隆、清宮啓之
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] 細胞分裂におけるテロメア結合蛋白質の新たな機能2008
- Author(s)
  清宮啓之
- Organizer
  第26回日本ヒト細胞学会学術集会
- Place of Presentation
  東京
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Anticancer effect of a telomerase inhibitor, MST-312, associated with telomere length and a premature aging-related protein2007
- Author(s)
  Seimiya, H.
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco CA, USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Tankyrase 1 suppresses mitotic abnormalities induced by Aurora A overexpression2007
- Author(s)
  Ohishi T, Tsuruo T, Seimiya H
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] タンキラーゼ1の細胞分裂における機能的関与2007
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第11回がん分子標的治療研究会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Tankyrase 1 suppresses mitotic abnormalities induced by Aurora A overexpression2007
- Author(s)
  大石智一、鶴尾隆、清宮啓之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor, MST-312, on human cancer cells2007
- Author(s)
  Seimiya, H.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & telomerase
- Place of Presentation
  Cold Spring Harbor NY, USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth2007
- Author(s)
  Seimiya, H.
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-18015047
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  清宮啓之, 鶴尾隆.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth.2007
- Author(s)
  清宮啓之, 鶴尾隆.
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-17012025
[Presentation] Intracellular reactions induced by a telomerase inhibitor and their impact on human cancer cell growth2007
- Author(s)
  Seimiya H, Tsuruo T
- Organizer
  The 8th Japan-Korea Joint Symposium on Cancer and Ageing Research
- Place of Presentation
  岐阜
- Year and Date
  2007-08-11
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor,MST-312,on human cancer cells2007
- Author(s)
  Seimiya, H.
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres&telomerase
- Place of Presentation
  Cold Siring Harbor NY,USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  Seimiya H, Tsuruo T
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Acute anti-proliferative effect of a synthetic telomerase inhibitor, MST-312, on human cancer cells2007
- Author(s)
  Seimiya H, Muramatsu Y, Sato S, Sakamoto M, Ohishi T, Tahara H, Yamori T, Tsuruo T
- Organizer
  Cold Spring Harbor Laboratory Meeting on Telomeres & telomerase
- Place of Presentation
  Cold Spring Harbor, NY, USA
- Year and Date
  2007-05-04
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cross-species difference in telomeric function of tankyrase 12007
- Author(s)
  村松由起子、大石智一、鶴尾隆、清宮啓之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Anticancer effect of a telomerase inhibitor, MST-312, associated with telomere length and a premature aging-related protein2007
- Author(s)
  Seimiya H, Muramatsu Y, Sato S, Tahara H, Yamori T, Tsuruo T
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Anticancer effect of a telomerase inhibitor,MST-312,associated with telomere length and a premature aging related protein2007
- Author(s)
  Seimiya, H.
- Organizer
  AACR Special Conference "The Role of Telomeres and Telomerase in Cancer Research"
- Place of Presentation
  San Francisco CA,USA
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19370078
[Presentation] Cancer therapy by a telomerase inhibitor, MST-3122007
- Author(s)
  Seimiya, H.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18015047

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196. FUJII Kazuki

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197. FUJII Hajime

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198. TANAKA Tetsu

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225. 武田純

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226. 中太智義

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Seimiya Hiroyuki 清宮 啓之

SEIMIYA Hiroyuki 清宮 啓之

清宮 啓之 セイミヤ ヒロユキ

Research Projects

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Co-Researchers

生命科学連携推進協議会

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先端モデル動物支援プラットフォーム

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グアニン四重鎖による翻訳制御に潜むがん細胞選択的な脆弱性Principal Investigator

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Molecular basis for cancer precision medicine targeting tankyrase poly(ADP-ribose) polymerasesPrincipal Investigator

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Investigation of novel molecular targets for oral cancer stem cells and establishment of novel oral cancer treatment strategy

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Molecular basis for cancer cell-specific vulnerability to disturbance of G-quadruplex dynamicsPrincipal Investigator

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Elucidating the functions of quadruplex nucleic acids by integrative molecular profiling of chemical signalsPrincipal Investigator

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Optimization of cancer therapeutic strategies that target tankyrase-specific PARylationPrincipal Investigator

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Molecular basis for the cross-sectional vulnerability of various cancers elicited by atypical nucleic acid configuration and its therapeutic applicationPrincipal Investigator

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Integrative functional analysis of G-quadruplex nucleic acids by utilizing natural and synthetic chemical tool moleculesPrincipal Investigator

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Synthetic lethality-based identification of drug-sensitive genome profilesPrincipal Investigator

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Advanced Animal Model Support

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Regulation of cell motility by poly(ADP-ribosyl)ation and its application to overcoming cancer invasion and metastasisPrincipal Investigator

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Seimiya Hiroyuki 清宮啓之

SEIMIYA Hiroyuki 清宮啓之

清宮啓之セイミヤヒロユキ