ZEMBUTSU HITOSHI 前佛均

… Alternative Names

ZEMBUTSU Hitoshi 前佛均

前佛均ゼンブツヒトシ

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Researcher Number	90372820
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, 客員研究員
Affiliation (based on the past Project Information) *help	2018 – 2021: 公益財団法人がん研究会, がんプレシジョン医療研究センターリキッドバイオプシー診断開発プロジェクト, プロジェクトリーダー(部長クラス) 2017: 公益財団法人がん研究会, がんプレシジョン医療研究センターリキッドバイオプシー診断開発プロジェクト, プロジェクトリーダー 2015: 札幌医科大学, 道民医療推進学講座, 講師 2015: 東京大学, 医科学研究所, 助教 2013 – 2014: 独立行政法人国立がん研究センター, 研究所, ユニット長 … More 2013: 札幌医科大学, 公私立大学の部局等, 講師 2012: 札幌医科大学, 道民医療推進学講座, 特任講師 2007: The University of Tokyo, 医科学研究所, 助教 2006: 東京大学, 医科学研究所, 助手 2004: 札幌医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnosis / Drug development chemistry Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Tumor diagnostics
Keywords	Principal Investigator 内分泌治療 / タモキシフェン / 乳癌 / 遺伝子診断 / 有効性 / 副作用 / ホルモン療法 / ターゲットリシークエンス / エクソーム / ゲノム解析 … More / 薬剤感受性 / 個別化内分泌療法 / C10orf11 / 遺伝子機能解析 / 個別化医療 / 乳がん / 抗癌剤耐性 / 術前化学療法 / ドセタキセル / 抗癌剤 / 薬剤反応性 / ゲノム / マイクロアレイ … More Except Principal Investigator リキッドバイオプシー / HGF / MMP / RANTES / bile duct cancer / liquid biopsy / 胆管がん / 閉塞性黄疸 / 胆汁リキッドバイオプシー / 無細胞DNA / 胆汁 / 肝外胆管がん / 治療効果予測 / 術前化学放射線療法 / 術前放射線化学療法 / 直腸癌 / PGx / 癌 / バイオマーカー / precision medicine / 抗がん剤 / xenograft / pharmacogenomics / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / Stroma cell / Invasion / Pancreas carcinoma / Colorectal carcinoma / Gastric carcinoma / CCR / 浸潤能 / 単核球 / VEGF-A / MMP-9 / 乳癌 / 間質細胞 / 浸潤 / 膵癌 / 大腸癌 / 胃癌 / 小型肝細胞 / ヒト細胞 / リモデリング / 骨髄 / 再生 / 幹細胞 / 肝臓 / 肝不全 / 組織再生 / 細胞移植 / 肝臓外科 / 消化器外科 Less

最適な乳がんホルモン療法を患者に届けるための新たな遺伝子診断法の開発Principal Investigator
- Principal Investigator
  
  前佛均
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Prediction of response to neoadjuvant chemoradiotherapy in rectal cancer using liquid biopsy
- Principal Investigator
  
  UENO Masashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Liquid biopsy for the bile: a novel diagnostic tool for extrahepatic bile duct cancer
- Principal Investigator
  
  Ito Hiromichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Exome sequencing of cancer related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs
- Principal Investigator
  
  Udagawa Chihiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Japanese Foundation for Cancer Research
Fundamental Researches for the Application of Human Small Hepatocytes in Clinical Treatment
- Principal Investigator
  
  HIRATA Koichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Sapporo Medical University
Identification and functional analysis of the gene(s) associated with endcrine therapy for breast cancer.Principal Investigator
- Principal Investigator
  
  ZEMBUTSU HITOSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  National Cancer Center Japan
  Sapporo Medical University
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
乳癌臨床検体を用いたドセタキセル耐性遺伝子の同定と機能解析Principal Investigator
- Principal Investigator
  
  前佛均
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokyo
Study of inhibition of the metastasis in gastrointestinal carcinoma targeting for RANTES receptor
- Principal Investigator
  
  FURUHATA Tomohisa
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Sapporo Medical University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] Tamoxifen Pharmacogenetics2013
- Author(s)
  Hitoshi Zembutsu
- Publisher
  The McGraw-Hill Companies(in press)
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Liquid biopsy for the detection of clinical biomarkers in early breast cancer: new insights and challenges2020
- Author(s)
  Matsutani Akiko、Udagawa Chihiro、Matsunaga Yuki、Nakamura Seigo、Zembutsu Hitoshi
- Journal Title
  
  Pharmacogenomics
  
  Volume: 21 Issue: 5 Pages: 359-367
- DOI
  10.2217/pgs-2019-0130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence2020
- Author(s)
  Murahashi Satoshi、Akiyoshi Takashi、Sano Takeshi、Fukunaga Yosuke、Noda Tetsuo、Ueno Masashi、Zembutsu Hitoshi
- Journal Title
  
  British Journal of Cancer
  
  Volume: - Issue: 5 Pages: 803-810
- DOI
  10.1038/s41416-020-0941-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07310, KAKENHI-PROJECT-20K09022, KAKENHI-PROJECT-18K08635, KAKENHI-PROJECT-18K08664
[Journal Article] Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer2019
- Author(s)
  Osumi Hiroki、Shinozaki Eiji、Takeda Yoshinori、Wakatsuki Takeru、Ichimura Takashi、Saiura Akio、Yamaguchi Kensei、Takahashi Shunji、Noda Tetsuo、Zembutsu Hitoshi
- Journal Title
  
  Cancer Medicine
  
  Volume: 8 Issue: 1 Pages: 408-417
- DOI
  10.1002/cam4.1913
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic colorectal cancer2019
- Author(s)
  Osumi Hiroki、Shinozaki Eiji、Yamaguchi Kensei、Zembutsu Hitoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1
- DOI
  10.1038/s41598-019-53711-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] Clinical utility of circulating tumor DNA for colorectal cancer2019
- Author(s)
  Osumi Hiroki、Shinozaki Eiji、Yamaguchi Kensei、Zembutsu Hitoshi
- Journal Title
  
  Cancer Science
  
  Volume: 110 Issue: 4 Pages: 1148-1155
- DOI
  10.1111/cas.13972
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] Whole genome sequencing to identify predictive markers for the risk of drug-induced interstitial lung disease2019
- Author(s)
  Udagawa Chihiro、Horinouchi Hidehito、Shiraishi Kouya、Kohno Takashi、Okusaka Takuji、Ueno Hideki、Tamura Kenji、Ohe Yuichiro、Zembutsu Hitoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 10 Pages: e0223371-e0223371
- DOI
  10.1371/journal.pone.0223371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] A Genome-Wide Association Study Identifies Five Novel Genetic Markers for Trastuzumab-Induced Cardiotoxicity in Japanese Population2019
- Author(s)
  Nakano Mari Hara、Udagawa Chihiro、Shimo Arata、Kojima Yasuyuki、Yoshie Reiko、Zaha Hisamitsu、Abe Norie、Motonari Tokiwa、Unesoko Mikiko、Tamura Kenji、Shimoi Tatsunori、Yoshida Masayuki、Yoshida Teruhiko、Sakamoto Hiromi、Kato Ken、Mushiroda Taisei、Tsugawa Koichiro、Zembutsu Hitoshi
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 12 Pages: 2045-2053
- DOI
  10.1248/bpb.b19-00527
- NAID
  130007754507
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] がんプレシジョン医療を目指したリキッドバイオプシー技術の臨床応用2018
- Author(s)
  前佛均
- Journal Title
  
  外科
  
  Volume: 80 Pages: 1200-1204
- Data Source
  KAKENHI-PROJECT-18K07310
[Journal Article] A prospective study to examine the accuracies and efficacies of prediction systems for response to neoadjuvant chemotherapy for muscle invasive bladder cancer.2018
- Author(s)
  Kato Y, Zembutsu H, Takata R, Matsuura T, Kato R, Kanehira M, Iwasaki K, Yamada N, Katagiri T, Sugai T, Fujioka T, Nakamura Y, Obara W.
- Journal Title
  
  Oncol Lett.
  
  Volume: 16 Pages: 5775-5784
- DOI
  10.3892/ol.2018.9330
- NAID
  120007099372
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K07310, KAKENHI-PLANNED-17H06419, KAKENHI-PROJECT-16H05153, KAKENHI-PROJECT-17K19601
[Journal Article] Targeted sequencing reveals genetic variants associated with sensitivity of 79 human cancer xenografts to anticancer drugs.2018
- Author(s)
  Udagawa C, Sasaki Y, Suemizu H, Ohnishi H, Tokino T, Zembutsu H
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 15 Pages: 1339-1359
- DOI
  10.3892/etm.2017.5533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-16K18445, KAKENHI-PROJECT-16H06279
[Journal Article] A genome-wide association study identifies three novel genetic markers for response to tamoxifen: A prospective multicenter study2018
- Author(s)
  Onishi Hiroshi、Udagawa Chihiro、Kubo Michiaki、Nakamura Seigo、Akashi-Tanaka Sadako、Kuwayama Takashi、Watanabe Chie、Endo Itaru、Zembutsu Hitoshi, et all.
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 8 Pages: e0201606-e0201606
- DOI
  10.1371/journal.pone.0201606
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310, KAKENHI-PROJECT-18K15332
[Journal Article] Pharmacogenomics toward personalized tamoxifen therapy for breast cancer.2015
- Author(s)
  Zembutsu H
- Journal Title
  
  Pharmacogenomics.
  
  Volume: 16 Issue: 3 Pages: 287-296
- DOI
  10.2217/pgs.14.171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Precision Medicine for Cancer and Pharmacogenomics.2015
- Author(s)
  Zembutsu H
- Journal Title
  
  血液内科
  
  Volume: 70 Pages: 527-532
- NAID
  40020439691
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] CYP2D6 Genotype and Adjuvant Tamoxifen: Meta-Analysis of Heterogeneous Study Populatins2014
- Author(s)
  Province MA, Goetz MP, Zembutsu H, et al
- Journal Title
  
  Clin Pharmacol Ther.
  
  Volume: 95 Issue: 2 Pages: 216-227
- DOI
  10.1038/clpt.2013.186
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).2014
- Author(s)
  Chhibber A, Mefford J, Zembutsu H et al
- Journal Title
  
  Pharmacogenomics J.
  
  Volume: 14 Issue: 4 Pages: 336-342
- DOI
  10.1038/tpj.2014.2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300338, KAKENHI-PROJECT-221S0001
[Journal Article] Lymph node shape in computed tomography imaging as a predictor for axillary lymph node metastasis in patients with breast cancer.2014
- Author(s)
  Kutomi G, Ohmura T, Zembutsu H et al
- Journal Title
  
  Exp Ther Med.
  
  Volume: 8 Issue: 2 Pages: 681-685
- DOI
  10.3892/etm.2014.1787
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] VAV3 mediates resistance to breast cancer endocrine therapy.2014
- Author(s)
  Aguilar H, Urruticoechea A,Zembutsu H,et al
- Journal Title
  
  Breast Cancer Res
  
  Volume: 16 Issue: 3
- DOI
  10.1186/bcr3664
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Integration of cell line and clinical trial genome-wide analyses supports apolygenic architecture of Paclitaxel-induced sensory peripheral neurxDpathy.2013
- Author(s)
  Wheeler HE, Gamazon ER, Zembutsu H, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 19 Issue: 2 Pages: 491-499
- DOI
  10.1158/1078-0432.ccr-12-2618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Genome-wide association study of chemotherapeutic agent-tnduced severe neutropenia/leucopenia for patients in Biobank Japan.2013
- Author(s)
  Low SK, Chung S, Zembutsu H, et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Issue: 8 Pages: 1074-1082
- DOI
  10.1111/cas.12186
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] ゲノムワイド関連解析による疾病関連遺伝子の同定　ケロイド2013
- Author(s)
  中島光子, 前佛均.
- Journal Title
  
  Surgery Frontier
  
  Volume: 20 Pages: 178-183
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] ゲノムワイド関連解析によるジェムシタビン副作用関連遺伝子の同定2013
- Author(s)
  前佛均, 清谷一馬, 宇野智子, 木村康利, 慈田泰誠, 光畑直喜, 伊奈志乃美, 鬼原史, 山上裕機, 平田公一, 中村祐輔
- Journal Title
  
  胆と膵(0388-9408)
  
  Volume: 34 Pages: 143-148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] 遺伝子解析による薬物反応性　有害事象　ゲノムワイド関連解析によるゲムシタビン副作用関連遺伝子の同定.2013
- Author(s)
  前佛均, 清谷一馬, 宇野智子, 木村康利, 莚田泰誠, 光畑直喜, 伊奈志乃美, 鬼原史, 山上裕機, 平田公一, 中村祐輔
- Journal Title
  
  Surgery Frontier
  
  Volume: 20 Pages: 198-201
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] A genome-wide association study of chemotherapy-induced alopecia in breast cancer patients.2013
- Author(s)
  Chung S,Low SK, Zembutsu H,et al
- Journal Title
  
  Breast Cancer Res.
  
  Volume: 15 Issue: 5
- DOI
  10.1186/bcr3475
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Important and critical scientific aspects in pharmacogenomics analysis: lessons from controversial results of tamoxifen and CYP2D6 studies.2013
- Author(s)
  Kiyotani K, Mushiroda T, Zembutsu H,et al
- Journal Title
  
  J Hum Genet
  
  Volume: 58 Issue: 6 Pages: 327-333
- DOI
  10.1038/jhg.2013.39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] 遺伝子解析による薬物反応性　抗腫瘍効果　浸潤性膀胱癌に対する術前化学療法　感受性予測システムの構築2013
- Author(s)
  加藤陽一郎, 高田亮, 岩崎一洋, 小原航, 藤岡知昭, 前佛均, 中村祐輔
- Journal Title
  
  Surgery Frontier
  
  Volume: 20 Pages: 194-197
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] ゲノムワイド関連解析による疾病関連遺伝子の同定子宮内膜症2013
- Author(s)
  宇野智子, 前佛均, 中村祐輔.
- Journal Title
  
  Surgery Frontier
  
  Volume: 20 Pages: 184-187
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] Genome-wide association meta-analysis identifies new endometriosis risk loci.2012
- Author(s)
  Nyholt DR, Low SK, Zembutsu H, et al.
- Journal Title
  
  Nat Genet.
  
  Volume: 44 Issue: 12 Pages: 1355-1359
- DOI
  10.1038/ng.2445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.2012
- Author(s)
  Cha PC, Zembutsu H, et al.
- Journal Title
  
  J Hum Genet.
  
  Volume: 57 Issue: 4 Pages: 235-237
- DOI
  10.1038/jhg.2012.9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy2012
- Author(s)
  Kazuma Kiyotani*, Satoko Uno*, Taisei Mushiroda, Atsushi Takahashi, Michiaki Kubo, Naoki Mitsuhata, Shinomi Ina, Chikashi Kihara, Yasutoshi Kimura, Hiroki Yamaue, Koichi Hirata, Yusuke Nakamura, Hitoshi Zembutsu
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 22 Issue: 4 Pages: 229-235
- DOI
  10.1097/fpc.0b013e32834e9eba
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-24300338
[Journal Article] Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA.2012
- Author(s)
  Low SK, Takahashi A, Cha PC, Zembutsu H, et al.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 21 Issue: 9 Pages: 2102-2110
- DOI
  10.1093/hmg/dds020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.2012
- Author(s)
  Baldwin RM, Owzar K, Zembutsu H, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Issue: 18 Pages: 5099-5109
- DOI
  10.1158/1078-0432.ccr-12-1590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300338
[Journal Article] A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with2012
- Author(s)
  Elgazzar S,
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Issue: 12 Pages: 766-71
- DOI
  10.1038/jhg.2012.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650592, KAKENHI-PROJECT-24300328, KAKENHI-PROJECT-24300338, KAKENHI-PUBLICLY-23134503
[Journal Article] A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese2011
- Author(s)
  K.Kiyotani, T.Mushiroda, T.Tsunoda, T.Morizono, N.Hosono, M.Kubo, Y.Tanigawara, CK.Imamura, DA.Flockhart, F.Aki, K.Hirata, Y.Takatsuka, M.Okazaki, S.Ohsumi, T.Yamakawa, M.Sasa, Y.Nakamura, H.Zembutsu
- Journal Title
  
  Human Molecular Genetics
  
  Volume: (オンライン出版済) Issue: 7 Pages: 1665-1672
- DOI
  10.1093/hmg/ddr597
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134008, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23390037, KAKENHI-PROJECT-24300338
[Journal Article] Genetically manipulated human embryonic stem cell-derived dendritic cells with immune regulatory function.2007
- Author(s)
  Senju S, Suemori H, Zembutsu H, et. al.
- Journal Title
  
  Stem Cells 11
  
  Pages: 2720-2729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689005
[Journal Article] Prediction of risk of disease recurrence by genome-wide cDNA microarray analysis in patients with Philadelphia chromosome-positive acute lymphoblastic leukemi a treated with imatinib-combined chemotherapy.2007
- Author(s)
  Zembutsu H., et. al.
- Journal Title
  
  International Journal of Oncology 2
  
  Pages: 313-322
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18689005
[Journal Article] Intraductal papillary mucinous neoplasms of the pancreas : an analysis of protein expression and clinical features.2006
- Author(s)
  Nishikawa N, Kimura Y, Okita K, Zembutsu H, Furuhata T, Katsuramaki T, Kimura S, Asanuma H, Hirata K.
- Journal Title
  
  J Hepatobiliary Pancreat Surg. 13(4)
  
  Pages: 327-335
- NAID
  10018169300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591333
[Journal Article] The interplay between gastric cancer cell lines and PBMCs, mediated by the CC chemokine RANTES plays an important role in tumor progression.2005
- Author(s)
  Okita K, Furuhata T, Kimura Y, Kawakami M, Yamaguchi K, Tsuruma T, Zembutsu H, Hirata K.
- Journal Title
  
  J Exp Clin Cancer Res. Sep;24(3)
  
  Pages: 439-46
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591333
[Presentation] Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic2020
- Author(s)
  Hitoshi Zembutsu、Hiroki Osumi、Eiji Shinozaki、Kensei Yamaguchi
- Organizer
  Advances in Liquid Biopsies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] 大腸がんにおける循環腫瘍細胞DNAの早期量的変化は化学療法有効性の予測マーカーとなり得る2019
- Author(s)
  前佛均、大隅寛木、篠崎英司、山口研成
- Organizer
  日本人類遺伝学会第64回大会
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Circulating tumor DNA assessed through amplicon-based next-generation sequencing and its clinical application.2019
- Author(s)
  Hitoshi Zembutsu, Hiroki Osumi, Eiji Shinozaki, Kensei Yamaguchi, Masato Ozaka, Takashi Sasaki, Marie Muramatsu, Naoki Sasahira.
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Whole genome sequencing to identify predictive marker for the risk of drug-induced interstitial lung disease.2019
- Author(s)
  H. Zembutsu、C. Udagawa、H. Horinouchi、K. Shiraishi、T. Kohno、T. Okusaka、H. Ueno、K. Tamura、Y. Ohe.
- Organizer
  ASHG 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Bile liquid biopsy for malignant biliary obstruction: a promising novel diagnostic tool in the era of precision medicine2019
- Author(s)
  伊藤寛倫、村松万里江、前佛均　他
- Organizer
  消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08692
[Presentation] Clinical relevance of cell-free DNA analysis with for bile juice assessed through amplicon-based deep sequencing for bile juice from patients with malignant biliary obstruction due to pancreato-biliary in bile duct and pancreatic cancer2019
- Author(s)
  M Muramatsu, H Ito, H Zembutsu
- Organizer
  AACR Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08692
[Presentation] 術前治療を施行した局所進行直腸癌を用いた定量的ctDNA解析と治療効果予測2019
- Author(s)
  村橋賢、秋吉高志、前佛均、上野雅資、福長洋介、佐野武、野田哲生
- Organizer
  第74回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08635
[Presentation] Clinical relevance of cell-free DNA analysis with amplicon-based deep sequencing for bile juice from patients with malignant biliary obstruction due to pancreato-biliary cancer2019
- Author(s)
  Marie Muramatsu, Hiromichi Ito, Hitoshi Zembutsu
- Organizer
  Annual meeting of American Asssociation for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08692
[Presentation] 術前治療を施行した進行直腸癌症例を用いたcirculating tumor DNAの経時的変化と病理学的完全奏効の関連解析2019
- Author(s)
  村橋賢、秋吉高志、前佛均、向井俊貴、山口智弘、長嵜寿矢、小西毅、長山聡、福長洋介、上野雅資
- Organizer
  第74回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08635
[Presentation] 大腸がんにおける循環腫瘍細胞DNAの早期量的変化は化学療法有効性の予測マーカーとなり得る2019
- Author(s)
  前佛均、大隅寛木、篠崎英司、山口研成
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Bile liquid biopsy for malignant biliary obstruction: a promising novel diagnostic tool in the era of precision medicine2019
- Author(s)
  Hiromichi Ito, Marie Muramatsu, Mamiko Miyashita, Hiroyuki Ono, Takafumi Sato, Yoshihiro Mise, Yosuke Inoue, Yu Takahashi, Akio Saiura, Hitoshi Zembutsu
- Organizer
  日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08692
[Presentation] 術前治療を施行した進行直腸癌症例を用いたctDNAの経時的変化と治療効果の関連解析2019
- Author(s)
  村橋賢、秋吉高志、前佛均、長嵜寿矢、小西毅、長山聡、福長洋介、上野雅資
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08635
[Presentation] Bile liquid biopsy for malignant biliary obstruction: A promising novel diagnostic tool in the era of precision medicine2019
- Author(s)
  伊藤寛倫、村松万里江、前佛均　他
- Organizer
  日本癌治療学会総会
- Data Source
  KAKENHI-PROJECT-18K08692
[Presentation] Clinical relevance of circulating tumor DNA assessed through amplicon-based next-generation sequencing.2019
- Author(s)
  Hitoshi Zembutsu, Hiroki Osumi, Eiji Shinozaki, Kensei Yamaguchi, Masato Ozaka, Takashi Sasaki, Naoki Sasahira.
- Organizer
  11th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] cfDNAパネルを用いたctDNA検出の臨床実用性の検証2018
- Author(s)
  前佛均
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Clinical relevance of circulating tumor DNA assessed through amplicon-based next-generation sequencing in cancer.2018
- Author(s)
  Hitoshi Zembutsu, Hiroki Osumi, Kensei Yamaguchi, Eiji Shinozaki, Masato Ozaka, Takashi Sasaki, Naoki Sasahira.
- Organizer
  ASHG Annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] 術前治療を施行した進行直腸癌症例を用いたcell free DNAの経時的変化と臨床病理学的因子の関連解析2018
- Author(s)
  村橋賢、秋吉高志、前佛均、長嵜寿矢、小西毅、藤本佳也、長山聡、福長洋介、上野雅資
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08635
[Presentation] 術前治療を施行した進行直腸癌症例を用いたcell free DNAの経時的変化と臨床病理学的因子の関連解析2018
- Author(s)
  村橋賢、秋吉高志、前佛均、長嵜寿矢、小西毅、藤本佳也、長山聡、福長洋介、上野雅資
- Organizer
  第73回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-18K08635
[Presentation] cfDNAパネルを用いたctDNA検出の臨床実用性の検討2018
- Author(s)
  前佛均
- Organizer
  第63回日本人類遺伝学会
- Data Source
  KAKENHI-PROJECT-18K07310
[Presentation] Exome sequencing of cancer related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs2017
- Author(s)
  Udagawa C, Sasaki Y, Suemizu H, Ohnishi Y, Ohnishi H, Tokino T, Zembutsu H.
- Organizer
  AACR Annual Meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18445
[Presentation] Exome sequencing of cancer related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs2016
- Author(s)
  Chihiro Udagawa, Takashi Tokino, Yasushi Sasaki, Bunsyo Shiotani, Yasuyuki Ohnishi, Hiroshi Suemizu and Hitoshi Zembutsu
- Organizer
  The American Society of Human Genetics Meeting 2016
- Place of Presentation
  Vancouver (Canada)
- Year and Date
  2016-10-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18445
[Presentation] Exome sequencing of cancer related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs2016
- Author(s)
  Chihiro Udagawa, Takashi Tokino, Yasushi Sasaki, Bunsyo Shiotani, Yasuyuki Ohnishi, Hiroshi Suemizu and Hitoshi Zembutsu
- Organizer
  第７５回日本癌学会
- Place of Presentation
  パシフィコ横浜（神奈川・横浜）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K18445
[Presentation] Serum biomarker screening for BRCTF1-targeted therapy. Poster Session2016
- Author(s)
  Gunji H, Taniguchi H, Imai K, Kutomi G, Shima H, Miyagi Y, Zembutsu H.
- Organizer
  10th Joint Conference of the American Association for Cancer Research（AACR）and the Japanese Cancer Association（JCA）
- Place of Presentation
  Maui, Hawaii, U.S.A.
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 遺伝子発現プロファイルに基づく乳がん術前化学療法感受性予測システムの構築2012
- Author(s)
  鈴木やすよ, 前佛均, 西舘敏彦, 植木知身, 九冨五郎, 高丸智子, 平田公一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] CYP2D6遺伝子多型によるTAM投与量調節治療2012
- Author(s)
  笹三徳, 清谷一馬, 筵田泰誠, 今村知世, 谷川原佑介, 細野直哉, 前佛均, 中村祐輔
- Organizer
  第20回日本乳癌学会総会
- Place of Presentation
  テトリアくまもと
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] 局所浸潤性膀胱癌に対するネオアジュバント療法感受性予測前向き試験2012
- Author(s)
  加藤陽一郎, 前佛均, et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] ゲノムワイド関連解析によるジエムザール副作用関連遺伝子の同定2012
- Author(s)
  前佛均, 清谷一馬, 中村祐輔, et al.
- Organizer
  日本人類遺伝学会第57回大会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] ゲノムワイド関連解析による膵癌発症関連遺伝子およびジェムシタビン副作用関連遺伝子の同定2012
- Author(s)
  前佛均, 口羽文, Siew-Kee Low Siew-Kee, et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市立教育文化会館
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] 遺伝子診断による乳癌オーダーメイド医療2012
- Author(s)
  前佛均, 平田公一, 安井寛, 神津英至, 和田卓郎
- Organizer
  第3回日本プライマリ・ケア連合学会学術大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-09-02
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] Predicting Response to Docetaxel Neoadjuvant Chemotherapy for Advanced Breast Cancers through Genome-Wide Gene Expression Profiling2007
- Author(s)
  前佛均
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18689005
[Presentation] PGxによるタモキシフェン治療効果予測：CYP2D6研究から学ぶこと
- Author(s)
  清谷一馬、莚田泰誠、前佛均、中村祐輔
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] Genome-wide association studies identify different susceptibility loci for various subtypes of epithelial ovarian cancer in the Japanese population
- Author(s)
  Hitoshi Zembutsu, Pei-Chieng Cha, Akira Hirasawa, Atsushi Takahashi, Tomoko Akahane, Siew-Kee Low, Michiaki Kubo, Daisuke Aoki, Yusuke Nakamura
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03 – 2013-10-05
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] A genome-wide association study (GWAS) of docetaxel-induced peripheral neuropathy in CALGB 90401 (Alliance)
- Author(s)
  Daniel Louis Hertz, Kouros Owzar, Susan Halabi, William Kevin Kelly, Hitoshi Zembutsu, et al
- Organizer
  ASCO Annual Meeting
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2013-05-31 – 2013-06-04
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] A prospective study to examine the availability of the prediction system of Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer
- Author(s)
  Yoichiro Kato, Hitoshi Zembutsu, Ryo Takata, Kazuhiro Iwasaki, Wataru Obara, Yusuke Nakamura, Tomoaki Fujioka
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03 – 2013-10-05
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] 網羅的遺伝子発現解析による筋層浸潤性膀胱がんのオーダーメイド医療
- Author(s)
  高田亮、加藤陽一郎、前佛均、片桐豊雅、角田達彦、藤岡知昭、中村祐輔、小原航
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] A replication study of a GWAS identified three genetic loci associated with clinical outcomes of patients with invasive breast cancer
- Author(s)
  Goro Kutomi, Koichi Hirata, Kazuma Kiyotani, Taisei Mushiroda, Tatsuhiko Tsunoda, Fuminori Aki, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura and Hitoshi Zembutsu
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-03 – 2013-10-05
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] CYP2D6 genotypeとタモキシフェン治療反応性の関係を解明する多施設共同前向き研究
- Author(s)
  前佛均、中村清吾、明石定子、桑山隆志、渡邊知映、武井寛幸、石川孝、長谷川善枝、リースーチン、松方絢美、松本広志、九冨五郎、中村祐輔
- Organizer
  日本人類遺伝学会第59回大会
- Place of Presentation
  東京
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] ゲノムワイド関連解析によるタモキシフェン反応性診断
- Author(s)
  前佛均, 平田公一, 岡崎稔, 安藝史典, 高塚雄一, 大住省三, 山川卓, 笹三徳, 中村祐輔
- Organizer
  日本外科学会第113回大会
- Place of Presentation
  福岡
- Year and Date
  2013-04-11 – 2013-04-13
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] CYP2D6 genotypeとタモキシフェン治療反応性の関係を解明する多施設共同前向き研究
- Author(s)
  前佛均、中村清吾、明石定子、桑山隆志、渡邊知映、武井寛幸、石川孝、長谷川善枝、リースーチン、松方絢美、松本広志、九冨五郎、中村祐輔
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24300338
[Presentation] Prospective Clinical Study to Clarify the Relationship between CYP2D6 Genotype and the Therapeutic Effects of Preoperative Tamoxifen Therapy
- Author(s)
  Hitoshi Zembutsu, Seigo Nakamura, Sadako Akashi, Takashi Kuwayama, Tomoko Takamaru, Yusuke Nakamura et al
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台
- Year and Date
  2013-11-20 – 2013-11-23
- Data Source
  KAKENHI-PROJECT-24300338

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ZEMBUTSU HITOSHI 前佛 均

ZEMBUTSU Hitoshi 前佛 均

前佛 均 ゼンブツ ヒトシ

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Co-Researchers

最適な乳がんホルモン療法を患者に届けるための新たな遺伝子診断法の開発Principal Investigator

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Prediction of response to neoadjuvant chemoradiotherapy in rectal cancer using liquid biopsy

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Liquid biopsy for the bile: a novel diagnostic tool for extrahepatic bile duct cancer

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Review Section

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Exome sequencing of cancer related genes to identify genetic markers for sensitivity to cytotoxic anticancer drugs

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Fundamental Researches for the Application of Human Small Hepatocytes in Clinical Treatment

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Identification and functional analysis of the gene(s) associated with endcrine therapy for breast cancer.Principal Investigator

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Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

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乳癌臨床検体を用いたドセタキセル耐性遺伝子の同定と機能解析Principal Investigator

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Study of inhibition of the metastasis in gastrointestinal carcinoma targeting for RANTES receptor

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[Book] Tamoxifen Pharmacogenetics2013

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[Journal Article] Liquid biopsy for the detection of clinical biomarkers in early breast cancer: new insights and challenges2020

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[Journal Article] Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence2020

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[Journal Article] Clinical relevance of circulating tumor DNA assessed through deep sequencing in patients with metastatic colorectal cancer2019

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[Journal Article] Early change in circulating tumor DNA as a potential predictor of response to chemotherapy in patients with metastatic colorectal cancer2019

Author(s)

ZEMBUTSU HITOSHI 前佛均

ZEMBUTSU Hitoshi 前佛均

前佛均ゼンブツヒトシ