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OSHIMURA Mitsuo  押村 光雄

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Researcher Number 20111619
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2014 – 2017: 鳥取大学, 染色体工学研究センター, 特任教授
2014: 鳥取大学, 大学院医学系研究科, 教授
2013: 鳥取大学, 染色体工学研究センター, 教授
2011: 鳥取大学, 大学院・医学系・研究科, 教授
2006 – 2011: 鳥取大学, 大学院・医学系研究科, 教授 … More
2004 – 2006: Graduate School of Medical Science, Professor, 大学院医学系研究科, 教授
2005: 鳥取大学, 医学系研究科, 教授
2004: 国立大学法人鳥取大学, 医学系研究科, 教授
2003: Tottori University, Graduate School of Medical Science, Professor, 大学院・医学系研究科, 教授
2000 – 2002: 鳥取大学, 医学部, 教授
1998: Faculty of Medicine, Tottori University, Professor, 教育学部, 教授
1990 – 1998: Prof., Faculty of Medicine, Tottori University, 医学部, 教授
1988 – 1989: 神奈川県立がんセンター, 臨床研究所, 室長 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Human genetics / Human genetics / Immunology / Cerebral neurosurgery / Laboratory animal science / Pediatrics / 基礎ゲノム科学
Except Principal Investigator
Urology / Laboratory animal science … More / Pediatrics / Drug development chemistry / Biological Sciences / Human genetics / Immunology Less
Keywords
Principal Investigator
FISH / 染色体工学 / 染色体導入 / ヒト人工染色体 / DT40 / ヒト21番染色体 / がん抑制遺伝子 / IGF2 / LIT1 / DMR … More / CD133 / Cre-LoxP / 人工染色体 / ES細胞 / 間葉系幹細胞 / 筋ジストロフィー / 遺伝子治療 / ヒト人工染色体ベクター / ダウン症候群 / モデルマウス / 微小核細胞融合法 / 染色体移入 / chromatin / epjgenetics / genomic imprinting / cancer / インプリントセンター / DNAメチル化 / ゲノム刷り込み / MAR / RNA / IGF / エピジェネティクス / クロマチン / エピジェネテノクス / 刷り込み遺伝子 / がん / CDM / transferin receptor / differentiation / ES cells / human chromosome / human melanoma specific antibody / TC mice / がん診断・治療 / ヒト染色体特異的抗体 / ヒト抗体ライブラリー / 細胞免疫染色 / ヒト染色体 / B16-F10 / 医薬品探索 / 分化マーカー / ヒト細胞表面抗原 / ヒトメラノーマ特異的抗体 / ヒト抗体産生マウス / Targeting / Translocation / Chromosome stability / TC mouse / Chromosome 10 / ターゲティング / 転座 / 染色体安定性 / TCマウス / 10番染色体 / Diagnosis / Telomere / Telomerase / Glioma / 予後 / 診断 / テロメア / テロメレース / グリオーマ / human chromosome 15 / sister chromatid exchange (SCE) / mapping / chromosome transfer / Bloom syndrome / 姉妹染色分体変換 / ヒト15番染色体 / 姉妹染色分体交換 / 遺伝子マッピング / ブルーム症候群 / モデル動物 / 小児血液学 / mesoangioblast細胞 / 遺伝子治療学 / コンディショナル遺伝子発現 / 染色体不安定性 / 染色体異数性 / M期チェックポイント / SIRT2 / マイクロアレイ / メチル化 / 個体差 / エピジェネティク / 一卵性双生児 / 染色体改変 / HAC / Human Artificial Chromosome / 遺伝子量効果 / ミオシン蛋白質 / 組織特異性 / 遺伝子発現 / 心奇形 / 行動異常 / ダウン症 / ヒト18番染色体 / 微小核融合法 / マウスメラノーマ細胞 / 微小核細胞融合 / 転移抑制遺伝子 / がん転移 / ヒトYL遺伝子 / マウスDT細胞 / 軟寒天内増殖 / 転写調節 / 増殖抑制 / 遺伝子導入 / 胃がん / DT細胞 / 腎細胞がん / 3番染色体 / 11番染色体 / 細胞老化 / 膀胱がん … More
Except Principal Investigator
染色体移入 / がん抑制遺伝子 / 微小核細胞融合 / ヒト3番染色体 / 発がん / 遺伝子 / 染色体 / 癌化 / 無限増殖性化 / 老化 / ヒト正常細胞 / German-Japanese collaborative program in cancer research / French-Japanese collaborative programe in cancer research / Growth Factors / Cytokines / Tumor Suppressor Genes / Oncogenes / Human Gene Mapping / International Exchange Program / 増殖因子 / サイトカイン / DNA修復 / ヒトがん遺伝子 / ヒトレトロウイルス / がん遺伝子 / chimeric mouse / mouse embryonic stem cell / human chromosome 21 / microcell-mediated chromosome transfer / キメラ / マウス / ES細胞 / 胚幹細胞 / ヒト染色体 / キメラマウス / 胚性幹細胞 / ヒト21番染色体 / グリセロール / グリセロール3-リン酸 / アミノ酸 / ピルビン酸ナトリウム / アスパラギン酸グルタミン酸ミトコンドリア膜輸送体 / 糖質毒性 / マウスモデル / シトリン欠損症 / 抗体医薬産生 / 人工染色体 / 抗体医薬 / ヒストンメチル化 / non-coding RNA / siRNAライブラリー / 刷り込みドメイン / ゲノム刷り込み / TSC2遺伝子 / INFα遺伝子 / 微小微小核融合法 / Ekerラット遺伝性腎癌 / 遺伝子発現 / サブトラクション法 / ガス抑制遺伝子 / ヒト腎細胞がん / IFNα領域の遺伝子欠損 / 第6染色体欠失 / 第5染色体欠失 / MNNGによる形質転換腎上皮細胞 / 子宮平滑筋肉腫 / 遺伝性腎癌 / Ekerラット / ヒト8番染色体 / 放射線感受性の補正 / SCIDマウス / 遺伝性腎細胞がん / ラット / 遺伝性腫瘍 / ウイルムス腫瘍 / 網膜芽細胞腫 / 家族性大腸ポリポージス / 突然変異 / ヘテロ接合性の消失 Less
  • Research Projects

    (32 results)
  • Research Products

    (87 results)
  • Co-Researchers

    (61 People)
  •  The elucidation of the carcinogenic mechanism of the Down's syndrome using chromosome engineering technologyPrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Pediatrics
    • Research Institution
      Tottori University
  •  Development of a novel model animal generation system using a mouse artificial chromosomePrincipal Investigator

    • Principal Investigator
      Mitsuo Oshimura
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tottori University
  •  To developtherapeutic and prophylactic procedures for citrin deficiency

    • Principal Investigator
      SAHEKI Takeyori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kumamoto University
  •  Development of the antibody drug production system using a highly efficient artificial chromosome vector.

    • Principal Investigator
      NISHIDA Tadashi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Drug development chemistry
    • Research Institution
      Tottori University
  •  Gene therapy of Duchenne muscular dystrophy using own stem cells and human artificial chromosomePrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  除去可能である新規遺伝子治療用人工染色体ベクターの開発Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  新規M期チェックポイントタンパクに着目する発がんにおける染色体不安定説の検証Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tottori University
  •  Construction of human artificial chromosome for gene therapy of Duchenne muscular dystrophyPrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  siRNAライブラリーを用いた刷り込み遺伝子発現調節分子の同定

    • Principal Investigator
      副島 英伸
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Saga University
  •  一卵性双生児ゲノム解析によるヒト個体差を作り出すゲノム領域の同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      基礎ゲノム科学
    • Research Institution
      Tottori University
  •  染色体改変に基づく新規ヒト人工染色体ベクターの構築Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  Genome-wide analysis of genomic impinting in cancerPrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tottori Univeisity
  •  ヒト21番染色体を保持するダウン症候群モデルマウスの作出とその原因遺伝子同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tottori University
  •  Generation of human chromosome-specific monoclonal antibodies using trans-chromosomic (TC) micePrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Tottori University
  •  ヒト21番染色体を保持するダウン症候群モデルマウスの作出とその原因遺伝子同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Tottori University
  •  Generation of ES cells that stably its translocation to mouse chromosomePrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  The development of animal model for chromosome trisomy-syndrome by microcell-mediated chromosome transfer

    • Principal Investigator
      FUNAKI Kenji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      Shimane University
  •  染色体導入による転移抑制遺伝子の同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tottori University
  •  グリオーマにおけるテロメレース活性およびテロメア長の臨床応用への検討Principal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      TOTTORI UNIVERSITY
  •  腎細胞の発癌過程におけるINFα領域の遺伝子欠損の意義

    • Principal Investigator
      舟木 賢治
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Tottori University
  •  腎細胞がんの腫瘍形質抑制に伴いその発現が変化する遺伝子の解析

    • Principal Investigator
      清水 素行
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Tottori University
  •  特定染色体導入によるがん抑制遺伝子の同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tottori University
  •  SCIDマウスの放射線感受性を補正するヒト8番染色体上遺伝子の単離

    • Principal Investigator
      清水 素行
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Tottori University
  •  Ekerラット遺伝性腫瘍の原因遺伝子マッピング

    • Principal Investigator
      FUNAKI Kenji
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  がん抑制に関与する遺伝子群の研究

    • Principal Investigator
      佐々木 正夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  特定染色体導入によるがん抑制遺伝子の同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tottori University
  •  腎細胞がん高発ラット細胞株を用いたヒト腎細胞がんのがん抑制遺伝子の解析

    • Principal Investigator
      清水 素行
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Tottori University
  •  Chromosomal mupping of a gene responsible for Bloom syndrome via microcell-mediated chromosome TransferPrincipal Investigator

    • Principal Investigator
      OSHIMURA Mitsuo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Tottori University
  •  特定染色体導入によるがん抑制遺伝子の同定Principal Investigator

    • Principal Investigator
      押村 光雄
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tottori University
  •  ヒト細胞の無限増殖性化に関与する染色体、遺伝子、およびその遺伝子機能に関する研究

    • Principal Investigator
      難波 正義
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kawasaki Medical School
  •  ヒト細胞の無限増殖性化に関与する染色体、遺伝子、および遺伝子機能に関する研究

    • Principal Investigator
      難波 正義
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kawasaki Medical School
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2004

All Journal Article Presentation Book Patent

  • [Book] 進化するゲノム編集技術、真下知士 城石俊彦 監修2015

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      341
    • Publisher
      (株)NTS
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Book] 進化するゲノム編集技術、真下知士 城石俊彦 監修2015

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      341
    • Publisher
      (株)NTS
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Book] ES・iPS細胞実験スタンダード、中辻憲夫 監修・末盛博文 編集2014

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      205
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Book] 今すぐ始めるゲノム編集、山本卓 編集2014

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      355
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Book] 実験医学別冊2014

    • Author(s)
      香月康宏、押村光雄(中辻憲夫 監修/末盛博文 編集)
    • Total Pages
      355
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Book] In vitro毒性・動態評価の最前線、小島肇夫 監修2013

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      204
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Book] In vitro毒性・動態評価の最前線、小島肇夫 監修2013

    • Author(s)
      香月康宏、押村光雄
    • Total Pages
      204
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Book] 幹細胞とヒト人工染色体ベクターの出会いVol.19, No.12007

    • Author(s)
      香月康宏、押村光雄
    • Publisher
      アニテックス
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Book] ヒト人工染色体ベクター導入と遺伝子・再生医療への可能性vol.10No.42006

    • Author(s)
      香月康宏、押村光雄
    • Publisher
      分子呼吸器病
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Book] 11Vol.5 No.42006

    • Author(s)
      平塚正治、押村光雄
    • Publisher
      再生医療
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Development of a multiple-gene-loading method by combining multi-integration system-equipped mouse artificial chromosome vector and CRISPR-Cas92018

    • Author(s)
      Honma Kazuhisa、Abe Satoshi、Endo Takeshi、Uno Narumi、Oshimura Mitsuo、Ohbayashi Tetsuya、Kazuki Yasuhiro
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 3 Pages: e0193642-e0193642

    • DOI

      10.1371/journal.pone.0193642

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15K12141
  • [Journal Article] Human and mouse artificial chromosome technologies for studies of pharmacokinetics and toxicokinetics2018

    • Author(s)
      Satoh Daisuke、Abe Satoshi、Kobayashi Kaoru、Nakajima Yoshihiro、Oshimura Mitsuo、Kazuki Yasuhiro
    • Journal Title

      Drug Metabolism and Pharmacokinetics

      Volume: 33 Issue: 1 Pages: 17-30

    • DOI

      10.1016/j.dmpk.2018.01.002

    • NAID

      210000187371

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-16H03295, KAKENHI-PROJECT-16K18942
  • [Journal Article] Combinations of chromosome transfer and genome editing for the development of cell/animal models of human disease and humanized animal models2017

    • Author(s)
      Uno Narumi、Abe Satoshi、Oshimura Mitsuo、Kazuki Yasuhiro
    • Journal Title

      Journal of Human Genetics

      Volume: 63 Issue: 2 Pages: 145-156

    • DOI

      10.1038/s10038-017-0378-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-15K19615
  • [Journal Article] Transfer of a mouse artificial chromosome into spermatogonial stem cells genetates transchromosomic mice,2017

    • Author(s)
      Shinohara T, Kazuki K, Ogonuki N, Morimoto H, Matoba S, Hiramatsu K, Honma K, Suzuki T, Hara T, Ogura A, Oshimura M, Kanatsu-Shinohara M, Kazuki Y.
    • Journal Title

      Stem Cell Reports.

      Volume: 9(4) Issue: 4 Pages: 1180-1191

    • DOI

      10.1016/j.stemcr.2017.08.012

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08136, KAKENHI-PUBLICLY-17H05639, KAKENHI-PLANNED-25112003, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-16H04728, KAKENHI-PROJECT-16H06146, KAKENHI-PROJECT-15K14362, KAKENHI-PROJECT-15K15013
  • [Journal Article] Multiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosome.2017

    • Author(s)
      Tomimatsu K, Kokura K, Nishida T, Yoshimura Y, Kazuki Y, Narita M, Oshimura M, Ohbayashi T.
    • Journal Title

      FEBS Open Bio.

      Volume: 7 Issue: 3 Pages: 306-317

    • DOI

      10.1002/2211-5463.12169

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-16K08548, KAKENHI-PROJECT-15K12141
  • [Journal Article] Highly Efficient Transfer of Chromosomes to a Broad Range of Target Cells Using Chinese Hamster Ovary Cells Expressing Murine Leukemia Virus-Derived Envelope Proteins.2016

    • Author(s)
      Suzuki T, Kazuki Y, Oshimura M, Hara T.
    • Journal Title

      PLoS One.

      Volume: 11 Issue: 6 Pages: e0157187-e0157187

    • DOI

      10.1371/journal.pone.0157187

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-15H04285, KAKENHI-PROJECT-16H04728
  • [Journal Article] 4.Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.2016

    • Author(s)
      Kokura K, Kuromi Y, Endo T, Anzai N, Kazuki Y, Oshimura M, Ohbayashi T.
    • Journal Title

      J Gene Med.

      Volume: 18 Issue: 10 Pages: 273-281

    • DOI

      10.1002/jgm.2925

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-26461258, KAKENHI-PROJECT-16K08548
  • [Journal Article] A pathway from chromosome transfer to engineering resulting in human and mouse artificial chromosomes for a variety of applications to bio-medical challenges.2015

    • Author(s)
      Oshimura Mitsuo, Uno Narumi, Kazuki Yasuhiro, Katoh Motonobu, Inoue Toshiaki
    • Journal Title

      Chromosome Res.

      Volume: 23 Issue: 1 Pages: 111-133

    • DOI

      10.1007/s10577-014-9459-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23570005, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-25640049, KAKENHI-PROJECT-15K01291, KAKENHI-PROJECT-15K07158
  • [Journal Article] Studies of Tumor Suppressor Genes via Chromosome Engineering.2015

    • Author(s)
      Kugoh H, Ohira T, Oshimura M.
    • Journal Title

      Cancers (Basel).

      Volume: 8 Issue: 1 Pages: 4-4

    • DOI

      10.3390/cancers8010004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08304, KAKENHI-PROJECT-25221308
  • [Journal Article] Retargeting of microcell fusion towards recipient cell-oriented transfer of human artificial chromosome2015

    • Author(s)
      Hiratsuka M, Ueda K, Uno N, Uno K, Fukuhara S, Kurosaki H, Takehara S, Osaki M, Kazuki Y, Kurosawa Y, Nakamura T, Katoh M, Oshimura M
    • Journal Title

      BMC Biotechnol.

      Volume: 15 Issue: 1 Pages: 58-58

    • DOI

      10.1186/s12896-015-0142-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K01291, KAKENHI-PROJECT-26460275, KAKENHI-PROJECT-26860733, KAKENHI-PROJECT-25221308
  • [Journal Article] Mouse embryonic stem cells with a multi-integrase mouse artificial chromosome for transchromosomic mouse generation.2015

    • Author(s)
      Yoshimura Y, Nakamura K, Endo T, Kajitani N, Kazuki K, Kazuki Y, Kugoh H, Oshimura M, Ohbayashi T.
    • Journal Title

      Transgenic Res.

      Volume: 24(4) Issue: 4 Pages: 717-727

    • DOI

      10.1007/s11248-015-9884-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K12141, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-25540134, KAKENHI-PROJECT-25640049
  • [Journal Article] A novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosome.2014

    • Author(s)
      Teruhiko Suzuki, Yasuhiro Kazuki, Mitsuo Oshimura, and Takahiko Hara
    • Journal Title

      PLoS One

      Volume: 9 Issue: 10 Pages: e110404-e110404

    • DOI

      10.1371/journal.pone.0110404

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24790696, KAKENHI-PROJECT-25221308
  • [Journal Article] Down syndrome-associated haematopoiesis abnormalities created by chromosome transfer and genome editing technologies2014

    • Author(s)
      Kazuki Y, Yakura Y, Abe S, Osaki M, Kajitani N, Kazuki K, Takehara S, Honma K, Suemori H, Yamazaki S, Sakuma T, Toki T, Shimizu R, Nakauchi H, Yamamoto T, Oshimura M
    • Journal Title

      Scientific reports

      Volume: 4 Issue: 1 Pages: 6136-6136

    • DOI

      10.1038/srep06136

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-25640044, KAKENHI-PROJECT-25713037, KAKENHI-PROJECT-25890014
  • [Journal Article] Highly stable maintenance of a mouse artificial chromosome in human cells and mice.2013

    • Author(s)
      Kazuki K, Takehara S, Uno N, Imaoka N, Abe S, Takiguchi M, Hiramatsu K, Oshimura M, Kazuki Y.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 442 Issue: 1-2 Pages: 44-50

    • DOI

      10.1016/j.bbrc.2013.10.171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25221308, KAKENHI-PROJECT-25640049
  • [Journal Article] Stem cell-mediated transfer of a human artificial chromosome ameliorates muscular dystrophy2011

    • Author(s)
      Tedesco FS, Hoshiya H, D' Antona G, Gerli MF, Messina G, Antonini S, Tonlorenzi R, Benedetti S, Berghella L, Torrente Y, Kazuki Y, Bottinelli R, Oshimura M, Cossu G.
    • Journal Title

      Sci Transl Med

      Volume: Volume 3, number 96 Issue: 96 Pages: 96-78

    • DOI

      10.1126/scitranslmed.3002342

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] Human Artificial Chromosomes for Gene Delivery and the Development of Animal Models2011

    • Author(s)
      Kazuki Y, Oshimura M.
    • Journal Title

      Mol Ther

      Volume: Volume 19, number 9 Issue: 9 Pages: 1591-601

    • DOI

      10.1038/mt.2011.136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] ヒト人工染色体ベクターによる遺伝子細胞治療へ向けて2011

    • Author(s)
      香月康宏、押村光雄
    • Journal Title

      日本臨床

      Volume: Vol.69, No.12 Pages: 2142-7

    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] Refined human artificial chromosome vectors for gene therapy and animal transgenesis2010

    • Author(s)
      Kazuki Y, Hoshiya H, Takiguchi M, Abe S, Iida Y, Osaki M, Katoh M, Hiratsuka M, Shirayoshi Y, Hiramatsu K, Ueno E, Kajitani N, Yoshino T, Kazuki K, Ishihara C, Takehara S, Tsuji S, Ejima F, Toyoda A, Sakaki Y, Larionov V, Kouprina N and Oshimura M
    • Journal Title

      Gene therapy

      Volume: Volume 18, number 4 Issue: 4 Pages: 384-93

    • DOI

      10.1038/gt.2010.147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249022, KAKENHI-PROJECT-22590301
  • [Journal Article] ヒト人工染色体ベクターの利点とその応用2010

    • Author(s)
      山口繁幸、大林徹也、香月康宏、押村光雄
    • Journal Title

      生化学

      Volume: Vol.82, No.9 Pages: 846-852

    • NAID

      10027502606

    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] Complete genetic correction of iPS cells from Duchenne muscular dystrophy2010

    • Author(s)
      Kazuki Y., Hiratsuka M., Takiguchi M., Osaki M., Kajitani N., Hoshiya H., Hiramatsu K., Yoshino T., Kazuki K., Ishihara C., Takehara S., Higaki K., Nakagawa M., Takahashi K., Yamanaka S. and Oshimura M.
    • Journal Title

      Mol. Therapy

      Volume: Volume18, number 2 Issue: 2 Pages: 386-93

    • DOI

      10.1038/mt.2009.274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] 筋ジストロフィー患者由来のiPS細胞における遺伝子修復~ヒト人工染色体ベクターによる新たな遺伝子治療戦略の可能性2010

    • Author(s)
      香月康宏、押村光雄
    • Journal Title

      Medical Bio

      Volume: Vol.7, No.2 Pages: 58-63

    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] 幹細胞のゲノム操作:ヒト人工染色体ベクターの開発2009

    • Author(s)
      香月康宏、押村光雄
    • Journal Title

      ゲノム医学

      Volume: Vol.9, No.3 Pages: 37-40

    • Data Source
      KAKENHI-PROJECT-21249022
  • [Journal Article] Transfer human artificial chromosome vectors into stem cells2008

    • Author(s)
      Oshimura M., Katoh M.
    • Journal Title

      Reproductive BioMedicine Online Vol.16 No.1

      Pages: 57-69

    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Correction of a genetic defect in multipotentGermline stem cells using a human artificial chromosome2008

    • Author(s)
      Kazuki Y., Hoshiya H., Kai Y., Abe S., Takiguchi M., Osaki M.,Kawazoe S., Katoh M., Kanatsu-Shinohara M., Inoue K., Kajitani N., Yoshino N., Shirayoshi Y., Ogura A., Shinohara T., BarrettJC., Oshimura M.
    • Journal Title

      Gene Therapy 15

      Pages: 617-24

    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] A highly stable and non-integrated human artificial chromosome(HAC) containing the 2.4Mb entire human dystrophin gene2008

    • Author(s)
      Hoshiya H., Kazuki Y., Abe S., Takiguchi M., Kajitani N., Watanabe Y., Yoshino T.,Shirayoshi Y., Higaki K., Messina G., Cossu G., Oshimura M.,
    • Journal Title

      Mol. Therapy

    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Telomerase-mediated life-span extension of human primary fibroblasts by human artificial chromosome (HAC) vector2008

    • Author(s)
      Shitara S, Kakeda M, Nagata K, Hiratsuka M, Sano A, Osawa K, Okazaki A, Katoh M, Kazuki Y, Oshimura M, Tomizuka K
    • Journal Title

      Biochem Biophys Res Commun Volume 369, number 3

      Pages: 807-11

    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Transfer of human artificial chromosome vectors into stem cells.2008

    • Author(s)
      Oshimura M
    • Journal Title

      Reprod Biomed Online. 16

      Pages: 57-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Human artificial chromosome vectors meet stem cells : new prospects for gene delivery2006

    • Author(s)
      Ren X, Tahimic CG, Katoh M, Kurimasa A, Inoue T, Oshimura M
    • Journal Title

      Stem Cell Rev 2

      Pages: 43-50

    • Data Source
      KAKENHI-PROJECT-18390107
  • [Journal Article] Loss of imprinting of PEG1/MEST in lung cancer cell lines.2004

    • Author(s)
      Nakanishi, H., Suda, T., Katoh, M., Watanabe, A., Igishi, T., Kodani, M., Matsumoto, S., Nakamoto, M., Shigeoka, Y, Okabe, T., Oshimura, M., Shimizu, E.
    • Journal Title

      Oncol.Rep. 12

      Pages: 1273-1278

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Journal Article] Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.2004

    • Author(s)
      Yu, W, Ginjala, V., Pant, V., Chernukhin, I., Whitehead, J., Docquier, F., Farrar, D., Tavoosidana, G., Mukhopadhyay, R., Kanduri, C., Oshimura.M..Feinberg, AP., Lobanenkov, V., Klenova, E., Ohlsson, R.
    • Journal Title

      Nat.Genet. 36

      Pages: 1105-1110

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Journal Article] Silencing of imprinted p57^<KIP2> gene expression is associated with loss of lustone H31ysine 9 methylation at DMR-LIT 1 in esophageal cancer.2004

    • Author(s)
      Soejima, H., Nakagawachi, T., Wei Z., Urano, T., Matsuoka, S., Higashimoto, K., Kitajima, Y., Takeuchi, M., Nakayama, M., Oshimura, M., Miyazaki, K., Joh, K., Mukai, T.
    • Journal Title

      Oncogene 23

      Pages: 4380-4388

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Journal Article] Dicer is essential for formation of the heterochromatin structure in vertebrate cells.2004

    • Author(s)
      Fukagawa, T., Nogami, M., Yoshikawa, M., Ikeno, M., Okazaki, T., Takami, Y., Nakayama, T., Oshimura, M.
    • Journal Title

      Nat.Cell.Biol. 6

      Pages: 784-791

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Journal Article] Coordinate downregulation of a novel imprinted transcript ITUP1 with PEG3 in glioma cell lines.2004

    • Author(s)
      Maegawa, S., Itaba, N., Otsuka, S., Kamitani, H., Watanabe, T., Tahimic, CGT., Nanba, E., Oshimura.M.
    • Journal Title

      DNA Resarch 11

      Pages: 37-49

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Journal Article] Imprinting analysis of 10 genes and/or transcripts in a 1.5-Mb MEST flanking region at human chromosome 7q32.2004

    • Author(s)
      Yamada, T., Mitsuya, K., Kayashima, T., Yamasaki, K., Ohta, T., Yoshiura, K., Matsumoto, N., Yamada, H., Minakami H., Oshimura, M., Niikawa, N., Kishino, T.
    • Journal Title

      Genomics. 83

      Pages: 402-412

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14026029
  • [Patent] マウス人工染色体ベクター2011

    • Inventor(s)
      押村光雄、香月康宏、滝口正人、松岡隆之
    • Industrial Property Rights Holder
      押村光雄、香月康宏、滝口正人、松岡隆之
    • Filing Date
      2011-01-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22890114
  • [Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007

    • Inventor(s)
      掛田実、富塚一磨、押村光雄、香月康宏
    • Industrial Property Rights Holder
      キリンファーマ株式会社
    • Filing Date
      2007-07-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Patent] ヒト人工染色体(HAC)ベクター及びヒト人工染色体(HAC)を有するヒト細胞医薬2007

    • Inventor(s)
      掛田実、富塚一磨、押村光雄、香月康宏
    • Filing Date
      2007-07-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Patent] 内在遺伝子を含まないヒト人工染色体ベクター2006

    • Inventor(s)
      押村光雄, 香月康宏, 松岡隆之
    • Industrial Property Rights Holder
      鳥取大学, 有限株式会社chromocenter
    • Industrial Property Number
      2006-127372
    • Filing Date
      2006-05-02
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Patent] 内在遺伝子を含まないヒト人工染色体ベクター2006

    • Inventor(s)
      押村光雄、香月康宏、松岡隆之
    • Industrial Property Number
      2006-127372
    • Filing Date
      2006-05-02
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] 鳥取大学発・世界最先端の染色体医工学技術を主軸とした新産業創出構想2017

    • Author(s)
      押村光雄
    • Organizer
      第7回北東アジア産業技術フォーラム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] ダウン症候群における白血病の病態解明に向けた病態モデル細胞の作製2017

    • Author(s)
      矢倉裕奈、赤木智美、阿部智志、宇野愛海、香月加奈子、押村光雄、香月康宏
    • Organizer
      日本人類遺伝学会第62回大会
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] 染色体医工学技術を用いた疾患の原因究明、治療法の開発2017

    • Author(s)
      久郷裕之, 宇野愛海, 大平崇人, 平塚正治, 香月康宏, 押村光雄
    • Organizer
      第40回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] ヒト・マウス人工染色体導入マウス及び細胞の構築と限りない応用の可能性2017

    • Author(s)
      押村光雄
    • Organizer
      かずさDNA千葉県バイオ・ライフサイエンス・ネットワーク会議
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] CHO細胞中におけるCRISPR/Cas9を用いた染色体改変技術の開発2016

    • Author(s)
      10. 宇野愛海、宇野勝洋、古本真也、末松拓郎、香月康宏、押村光雄
    • Organizer
      日本ゲノム編集学会第一回大会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2016-09-06
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] 人工染色体技術による創薬研究への応用2016

    • Author(s)
      押村光雄
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Presentation] 人工染色体技術による創薬研究への応用2016

    • Author(s)
      押村光雄
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] CHO-intermediated Chromosome Engineering (CHOiCE) technique using CRIPSR/Cas9.2016

    • Author(s)
      Uno N, Uno K, Komoto S, Kazuki Y, and Oshimura M
    • Organizer
      The 13th International Congress of Human Genetics (ICHG)
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] Human and mouse artificial chromosomes for bio-medical charanges2015

    • Author(s)
      Oshimura M.
    • Organizer
      Future of Biomedicine 2015
    • Place of Presentation
      Vladivostock, Russia
    • Year and Date
      2015-09-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Presentation] Human and mouse artificial chromosomes for bio-medical charanges2015

    • Author(s)
      Oshimura M.
    • Organizer
      Future of Biomedicine 2015
    • Place of Presentation
      ウラジオストク、ロシア
    • Year and Date
      2015-09-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] ヒト細胞とマウス個体において極めて安定に維持されるマウス人工染色体2014

    • Author(s)
      宇野愛海、香月加奈子、嵩原昇子、今岡奈津子、阿部智志、滝口正人、平松敬、香月康宏、押村光雄
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-05-16
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Presentation] ヒト細胞とマウス個体において極めて安定に維持されるマウス人工染色体2014

    • Author(s)
      宇野愛海、香月加奈子、嵩原昇子、今岡奈津子、阿部智志、滝口正人、平松敬、香月康宏、押村光雄
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-05-16
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] 染色体工学技術とゲノム編集技術の融合によるダウン症候群モデル細胞・動物の作製2014

    • Author(s)
      香月康宏、押村光雄
    • Organizer
      第4回ゲノム編集研究会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2014-10-06
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] 染色体工学技術とゲノム編集技術によるヒト化薬物代謝モデル動物の作製2014

    • Author(s)
      香月康宏、小林カオル、平林真澄、佐久間哲史、久世治朗、阿部智志、滝口正人、平松敬、本間和久、梶谷尚世、嵩原昇子、香月加奈子、千葉寛、山本卓、押村光雄
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-05-16
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] New Vectors for Gene Delivery: Human and Mouse Artificial Chromosomes2013

    • Author(s)
      Oshimura M.
    • Organizer
      117th OMICS Group conference
    • Place of Presentation
      USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-25640049
  • [Presentation] New Vectors for Gene Delivery: Human and Mouse Artificial Chromosomes2013

    • Author(s)
      Oshimura M.
    • Organizer
      117th OMICS Group conference
    • Place of Presentation
      USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-25221308
  • [Presentation] Human artificial chromosomes for gene delivery and stable expression2012

    • Author(s)
      Oshimura M
    • Organizer
      11^<th> Annual PEP TALK
    • Place of Presentation
      San Diego (Califolnia)
    • Year and Date
      2012-01-09
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] 遺伝子発現ベクターとしての人工染色体2012

    • Author(s)
      押村光雄
    • Organizer
      再生医療の実現化プロジェクト」ヒト多能性幹細胞の培養・解析の標準化レクチャーシリーズ第6回「幹細胞の遺伝子操作の実践(つぼ)
    • Place of Presentation
      理化学研究所(兵庫県)
    • Year and Date
      2012-02-02
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] 人工染色体ベクターを用いた好感度毒性評価の作成2012

    • Author(s)
      西田直史、吉村裕貴、佐々木勝崇、中島芳浩、押村光雄、大林徹也
    • Organizer
      第39回日本毒性学会学術年会
    • Place of Presentation
      仙台国際センター(宮城)
    • Data Source
      KAKENHI-PROJECT-22890114
  • [Presentation] 遺伝子発現ベクターとしての人工染色体2012

    • Author(s)
      押村光雄
    • Organizer
      文部科学省「再生医療の実現化プロジェクト」ヒト多能性幹細胞の培養・解析の標準化レクチャーシリーズ第6回「幹細胞の遺伝子操作の実践(つぼ)」
    • Place of Presentation
      理化学研究所(兵庫県)(招待講演)
    • Year and Date
      2012-02-02
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] APPLYING A HUMAN ARTIFICIAL CHROMOSOME VECTOR TO DE VELOP A HIGH-SENSITIVE BIOSENSOR CELL AS IN VITRO RISK ASSESSMENT METHOD2012

    • Author(s)
      T. Nishida, Y. Yoshimura, Y. Nakajima, Y. Ohmiya, T. Ohbayashi, N. Tanaka and M. Oshimura
    • Organizer
      2012Society of Toxicology Annual Meeting
    • Place of Presentation
      Moscone convention center, San Francisco(USA)
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-22890114
  • [Presentation] Human artificial chromosomes for gene delivery and stable expression2012

    • Author(s)
      Oshimura M
    • Organizer
      11th Annual PEP TALK
    • Place of Presentation
      SanDiego(Califolnia)
    • Year and Date
      2012-01-09
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] Human artificial chromosomes for gene delivery2011

    • Author(s)
      Oshimura M
    • Organizer
      World stem cell summit
    • Place of Presentation
      Pasadena (Califolnia)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] Development of a high-sensitivity toxicity test system using chromosome engineering and bioluminescence technology2011

    • Author(s)
      T. Nishida, Y. Yoshimura, K. Sasaki, Y. Nakajima, R. Saito, Y. Kazuki, S. Nishii, Y. Ohmiya, S. Aiba, M. Oshimura and T. Ohbayashi
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22890114
  • [Presentation] Human artificial chromosomes for gene delivery2011

    • Author(s)
      Oshimura M
    • Organizer
      World stem cell summit
    • Place of Presentation
      Pasadena(Califolnia)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] ヒト人工染色体を用いた遺伝子・再生医療への挑戦2011

    • Author(s)
      押村光雄
    • Organizer
      文部科学省iPS細胞等研究ネットワーク第3回合同シンポジウム
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] ヒト人工染色体を用いた遺伝子・再生医療への挑戦2011

    • Author(s)
      押村光雄
    • Organizer
      文部科学省iPS細胞等研究ネットワーク第3回合同シンポジウム
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-11-19
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] 人工染色体を用いた遺伝子/再生医療2010

    • Author(s)
      押村光雄
    • Organizer
      第180回川崎医学会講演会
    • Place of Presentation
      川崎医科大学(倉敷)(招待講演)
    • Year and Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] 人工染色体を用いた遺伝子/再生医療2010

    • Author(s)
      押村光雄
    • Organizer
      第180回川崎医学会講演会
    • Place of Presentation
      川崎医科大学(倉敷)
    • Year and Date
      2010-05-12
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] Human artificial chromosome and its medical and pharmaceutical applications2010

    • Author(s)
      押村光雄
    • Organizer
      The 4th Asian Chromosome Colloquium(ACC4) Plenary Lectures
    • Place of Presentation
      Fragrant Hill Empark Hotel(北京・中国)
    • Year and Date
      2010-10-12
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] Human artificial chromosome and its medical and pharmaceutical applications2010

    • Author(s)
      押村光雄
    • Organizer
      The 4^<th> Asian Chromosome Colloquium (ACC4) Plenary Lectures
    • Place of Presentation
      Fragrant Hill Empark Hotel(北京・中国)
    • Year and Date
      2010-10-12
    • Data Source
      KAKENHI-PROJECT-21249022
  • [Presentation] 多能性精原幹細胞(mGS)とヒト人工染色体ベクターを用いた欠損型遺伝子治療を目指して2008

    • Author(s)
      阿部智志、香月康宏、星谷英寿、甲斐義輝、滝口正人、尾崎克彦、川添真史郎、加藤基伸、篠原美都、井上貴美子、梶谷尚世、吉野とう子、白吉安昭、小倉淳郎、篠原隆司、押村光雄
    • Organizer
      第7回日本再生医療学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] A novel human artificial chromosome (HAC) for gene therapy and animal transgenesis2008

    • Author(s)
      Kazuki Y., Hoshiya H., Abe S., Takiguchi M., Iida Y., Watanabe Y., Osaki M., Katoh M., Kajitani N., Yoshino T., Shirayoshi Y., Hiratsuka M., Kurimasa K., and Oshimura M.
    • Organizer
      ASGT 11th annual meeting
    • Place of Presentation
      U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] ジストロフィンゲノムDNA(2.5Mb)を搭載したHAC ベクター : 遺伝子治療を目指して2008

    • Author(s)
      星谷英寿、香月康宏、甲斐義輝、阿部智志、滝口正人、飯田雄一 ,渡辺義徳, 尾崎克彦、梶谷尚世,吉野とう子,白吉安昭 ,押村光雄
    • Organizer
      第7回日本再生医療学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] A human artificial chromosome (HAC) vector with about 2.4 Mb-human Dystrophin genome including native expression control elements2008

    • Author(s)
      Hoshiya H., Kazuki Y., Abe S., Kai Y., Takiguchi M., Iida Y., Watanabe Y., Osaki M., Kajitani N., Yoshino T., Shirayoshi Y. and Oshimura M.
    • Organizer
      ASGT 11^<th> annual meeting
    • Place of Presentation
      U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] 遺伝子治療に向けた新規遺伝子治療用ヒト人工染色体ベクターの開発2008

    • Author(s)
      香月康宏, 星谷英寿, 甲斐義輝, 阿部智志, 滝口正人, 飯田雄一, 渡辺義徳, 尾崎克彦, 梶谷尚世, 吉野とう子, 白吉安昭, 富松望, 平塚正治, 栗政明弘, 押村光雄
    • Organizer
      第7回日本再生医療学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] 新規ヒト人工染色体ベクターの構築 : サブテロメアを用いた高発現ベクター系2008

    • Author(s)
      掛田実、永田恵子、佐野暁子、大澤加奈子、岡崎晃代、設楽真吾、香月康宏、押村光雄、富塚一磨
    • Organizer
      第6回幹細胞シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390107
  • [Presentation] Functional restoration of a genetic defect in multipotent germline stem cells by human artificial chromosome containing a genomic insert2006

    • Author(s)
      Kazuki Y., Hoshiya, H., Kai Y., Abe S., Takiguchi M., Osaki M., Kanatsu-Shinohara M., Kajitani N., ShirayoshiY., Hratsuka M., Ogura A., Shinohara T.and Oshimura, M
    • Organizer
      ASGT 9^<th> annual meeting
    • Place of Presentation
      U.S.A.
    • Data Source
      KAKENHI-PROJECT-18390107
  • 1.  清水 素行 (80130756)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  KUGOH Hiroyuki (40225131)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 3.  KATO Motonobu (00273904)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 8 results
  • 4.  目黒 牧子 (20304222)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  FUNAKI Kenji (90091579)
    # of Collaborated Projects: 3 results
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  • 6.  SHIRAYOSHI Yasuaki (90249946)
    # of Collaborated Projects: 3 results
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  • 7.  KAZUKI Yasuhiro (90403401)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 21 results
  • 8.  YOKOTA Jun (10191503)
    # of Collaborated Projects: 2 results
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  • 9.  OSAKI Mitsuhiko (40325006)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 10.  難波 正義 (80069004)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  NISHIDA Tadashi (50588556)
    # of Collaborated Projects: 1 results
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  • 12.  OHBAYASHI Tetsuya (80348804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  SAHEKI Takeyori (10056070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  USHIKAI Miharu (70232816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  YAMAMURA Ken-ichi (90115197)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  KAMITANI Hideki (70194967)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HORI Tomokatsu (60010443)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HAYASHI Shinnichi (50208617)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KUROKI Toshio (90006073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  TANAKA Kiyoji (80144450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  HAYATSU Hikoya (10012593)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  AKIYAMA Tetsu (70150745)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  TAKEBE Hiraku (10028318)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ISHIKAWA Takatoshi (30085633)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  OHNO Shigeo (10142027)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  FUJII Yoshiaki (00098146)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  NISHIMURA Susumu (20076970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  YOSHIDA Mitsuaki (80012607)
    # of Collaborated Projects: 1 results
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  • 29.  SHIMOTOHNO Kunitada (10000259)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ARIGA Hiroyoshi (20143505)
    # of Collaborated Projects: 1 results
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  • 31.  ISHII Shunsuke (00124785)
    # of Collaborated Projects: 1 results
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  • 32.  HAKURA Akira (00029779)
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  • 33.  HAYAMI Masanori (40072946)
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  • 34.  HINO Shigeo (70012763)
    # of Collaborated Projects: 1 results
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  • 35.  TAKATSUKI Kiyoshi (80026830)
    # of Collaborated Projects: 1 results
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  • 36.  OSAME Mitsuhiro (10041435)
    # of Collaborated Projects: 1 results
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  • 37.  YODOI Junji (80108993)
    # of Collaborated Projects: 1 results
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  • 38.  TAKEICHI Noritoshi (40002133)
    # of Collaborated Projects: 1 results
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  • 39.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 1 results
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  • 40.  NISHIDA Yasuyoshi (50107059)
    # of Collaborated Projects: 1 results
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  • 41.  NODA Tohru (30146708)
    # of Collaborated Projects: 1 results
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  • 42.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 1 results
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  • 43.  NAGAO Minako (40100151)
    # of Collaborated Projects: 1 results
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  • 44.  YAMAMOTO Tadashi (40134621)
    # of Collaborated Projects: 1 results
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  • 45.  TOYOSHIMA Kumao (90029760)
    # of Collaborated Projects: 1 results
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  • 46.  濃野 勉 (20098619)
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  • 47.  佐々木 正夫 (20013857)
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  • 48.  北山 仁志 (30231286)
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  • 49.  宇都宮 譲二 (70013901)
    # of Collaborated Projects: 1 results
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  • 50.  高井 新一郎 (80028513)
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  • 51.  副島 英伸 (30304885)
    # of Collaborated Projects: 1 results
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  • 52.  三ツ矢 幸造 (30375191)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  平塚 正治 (00362872)
    # of Collaborated Projects: 1 results
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  • 54.  井上 敏昭 (80305573)
    # of Collaborated Projects: 1 results
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  • 55.  佐藤 建三 (40113196)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  TOMIZUKA Kazuma
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  OHIRA Takahito
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 58.  中村 和臣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 59.  鈴木 輝彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 60.  森本 裕子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 61.  中内 啓光
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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