Ogasawara Tohru 小笠原徹

… Alternative Names

OGASAWARA Toru 小笠原徹

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Researcher Number	20359623
Other IDs
Affiliation (Current)	2025: 東京大学, 保健・健康推進本部, 講師
Affiliation (based on the past Project Information) *help	2019 – 2025: 東京大学, 保健・健康推進本部, 講師 2009 – 2019: 東京大学, 医学部附属病院, 講師 2015: 東京大学, 医学部付属病院, 講師 2012: 東京大学, 医学部付属病院, 講師 2007 – 2008: The University of Tokyo, Faculty of Medicine, Lecturer … More 2006 – 2007: 東京大学, 医学部附属病院, 講師 2006: 東京大学, 医学部附属病院, 客員教員 2006: 東京大学, 医学部附属病院, 寄付講座教員(助教相当) 2006: 東京大学, 医学部附属病院, 寄附講座教員 2004 – 2006: 東京大学, 医学部附属病院, 寄付講座教員 2003 – 2005: 東京大学, 医学部附属病院, 助手 2004: 東京大学, 医学部附属病院, 寄附講座教員 Less
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Oral Science and related fields Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Orthodontic/Pediatric dentistry / Orthopaedic surgery / Morphological basic dentistry / Kidney internal medicine / 補綴理工系歯学 / Biomedical engineering/Biological material science
Keywords	Principal Investigator 細胞周期 / 再生医学 / 骨代謝 / 細胞分化 / 骨代謝学 / 発生・分化 / シグナル伝達 / 骨再生 / 再生医療 / 骨軟骨代謝学 … More / G0/G1期 / 骨格幹細胞 / microRNA / micro RNA / エクソソーム / 骨軟骨分化 / 骨吸収 / 骨形成 / 幹細胞 / ノックアウトマウス / クロマチン免疫沈降法 / 骨系統疾患 / 遺伝子操作マウス / 骨軟骨 / Cdk6 / 分化 / p38 / NF-κB / Smad / 軟骨細胞 / 破骨細胞 / 骨芽細胞 / CDK6 … More Except Principal Investigator 骨再生 / 再生医学 / 再生医療 / 口腔がん / 分化 / 液性因子 / 軟骨 / 三次元培養 / 軟骨細胞 / 増殖 / エピジェネティクス / Bone Metabolism / Dentistry / 骨代謝 / 歯学 / osseointegration / CGK II / 細胞分化 / Cdk6 / 統計的手法 / 脱分化 / 細胞融合 / LOX-1 / 破骨細胞 / 炎症性骨破壊 / 転写因子 / 歯科矯正学 / ノックアウトマウス / 遺伝子治療 / siRNA / 化合物デリバリーシステム / 化合物スクリーニング / 骨再生療法 / 人工骨 / 軟骨再生 / 移植・再生医療 / 骨芽細胞 / 顎顔面 / 足場素材 / 間葉系細胞 / 骨 / 滑膜 / 関節滑膜組織 / 顎関節症 / 関節軟骨 / ルブリシン / 変形性関節症 / DNAメチル化 / 口腔粘膜 / 骨再生医療 / 骨代謝制御機構 / ジンクフィンガープロテイン / 脂質 / 炎症整骨破壊 / ABCG1 / phosphatidylethanolamine / 細胞膜外葉 / LDL受容体 / Bone Regenerative Medicine / 顎裂部骨欠損 / 骨分化 / 骨再生医学 / stem cell / regenerative medicine / bone, cartilage / Nanog遺伝子 / 骨軟骨 / 幹細胞 / 骨・軟骨 / cell adhesion / titanium / MPC polymer / biocompatibility / チタン合金 / 細胞接着 / チタン / MPCポリマー / 生体適合性 / Regenerative Medicine / 口唇口蓋裂 / 再生骨軟骨 / implant / knockout mouse / cyclooxygenase 2 / prostaglandin / コンタクトマイクロラジオグラム / マイクロインプラント / シクロオキシゲナーゼ2(COX-2) / プロスタグランジン(PG) / インプラント / シクロオキシゲナーゼ2 / プロスタグランジン / differentiation / proliferation / 3D culture / soluble factor / hydrogel / chondrocyte / tissue engineering / nanotechnology / ハイドロゲル / ナノテクノロジー / cell differentiation / statistical analysis / temporomandibular joint / dedifferentiation / humoral factor / cartilage regeneration / CGKII / 顎関節 / 再生軟骨 / ヒトパピローマウィルス / HPV / 軸索ガイダンス因子 / スフィンゴ脂質 / S1P / 口腔癌 / RANKL産生 / 炎症性骨吸収 / 破骨細胞形成 / 腎移植 / siRNA治療 / siRNAデリバリー / 腎不全 / 癌治療 / 腎移植拒絶反応抑制 / 核酸治療 / siRNAキャリア / siRNAキャリアー / 免疫寛容 / 腎移植拒絶反応 / 遺伝子ノックダウン / 遺伝子導入 / 低分子化合物 / ナノDDS / 骨移植片 / 生理活性物質 / 骨再生用移植片 / ナノバイオ / 医療・福祉 / 生体適合材料 / ATDC細胞 / ATDC5細胞 / ATDC5 細胞 / DGキナーゼ / 顎骨再建 / 口腔顎顔面再建外科学 / 副甲状腺ホルモン / 顎裂部骨移植 / 骨再生治療 / Wntシグナル / G蛋白 / 顎顔面骨再生 / 骨形成 / βカテニン / PTHrP受容体 / PTH/PTHrP受容体 / PTH / β-catenin / PTHシグナル / (1)骨再生療法 / 骨形成性低分子化合物 / 膜性骨 / 骨折治癒 / COX-2 / 口腔外科学一般 / 高リン血症 / 高カリウム血症 / 低カルシウム血症 / 腎電解質代謝 / カルシウム感知受容体 / 遺伝子治療3 / 骨異栄養症 / 慢性腎不全 / 低Ca血症 / 腎電解質異常 / Ca感知受容体 / 副甲状腺機能低下症 / 腎機能低下 / カルシウム代謝 / バーター症候群 / ナノ送達システム / 骨分化シグナル / 三次元造形法 / 骨再生インプラント / Colla1GFP / インクジェットプリンター / トランスレーショナルリサーチ / シグナル伝達 / 生分解性ポリマー / Cyclin Dl / アポトーシス / p53 / Cyclin D1 / CDK6 / CAD / 三次元造型 / トランスジェニックマウス / Cyclin dependent kinase / サイクリン / 細胞周期 Less

Cdk4/Cdk6による古典的細胞周期制御と転写制御の統合的理解による骨代謝機構の解明Principal Investigator
- Principal Investigator
  
  小笠原徹
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
The mechanism of joint homeostasis in the coupling of articular cartilage and synovium
- Principal Investigator
  
  矢野文子
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Showa University
慢性機械刺激により口腔粘膜に蓄積するエピゲノム異常の同定とリスクマーカーへの応用
- Principal Investigator
  
  阿部雅修
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Identification of the microbiome associated with oral cancer and epigenomic abnormalities that reflect risk
- Principal Investigator
  
  Abe Masanobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Cdk6による骨格幹細胞G0/G1期制御機構の解明と骨再生医療に向けた基礎的検討Principal Investigator
- Principal Investigator
  
  小笠原徹
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokyo
Identification of genetic and epigenetic abnormalities in oral mucosa
- Principal Investigator
  
  Abe Masanobu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Identification of novel osteoclast-osteoblast coupling factors in exosomes involving cell cycle machineryPrincipal Investigator
- Principal Investigator
  
  Ogasawara Toru
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  The University of Tokyo
Elucidation of Involvement of LOX-1 in inflammatory bone destruction and the molecular mechanism for the LOX-1 actions, and an approach to develop the new drug for bone diseases.
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Possible involvement of of zinc finger protein family in bone metabolism and bone regenerative medicine
- Principal Investigator
  
  MORI Yoshiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Jichi Medical University
Identification of microRNAs controlled by Cdk6 for understanding of bone metabolism system and their application for regenerative medicinePrincipal Investigator
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Genome-wide screening of epigenetic abnormalities which are related with the prognosis of patients with HPV related oral cancers
- Principal Investigator
  
  Abe Masanobut
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
The elucidation of the role of lipid in bone resorption of inflammatory bone diseases; in particular, the exploration of the role of LOX-1 as an oxidized LDL receptor
- Principal Investigator
  
  HAKEDA Yoshiyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Study on sphingosine-1-phosphate signaling pathways in multistage carcinogenesis of the oral cancer
- Principal Investigator
  
  Takahiro Abe
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Investigation of factors which simultaneously regulate bone formation and bone resorption in terms of cell cycle regulation.Principal Investigator
- Principal Investigator
  
  OGASAWARA TORU
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Elucidation of the mechanism of bone metabolism controlled by Cdk6 transcription factoryPrincipal Investigator
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
siRNA carrier strategy to inhibit to rejection of transplanted kidneys
- Principal Investigator
  
  Watanabe Sumiyo
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Smart modification of PEEK by self-initiated surface graft polymerization for orthopedic bearings
- Principal Investigator
  
  TAKATORI Yoshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  The University of Tokyo
Examination of hybrid bone grafts using nano DDS and artificial bones
- Principal Investigator
  
  MORI Yoshiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Optimization of the bone regeneration system using small molecules and examination of its molecular mechanisms
- Principal Investigator
  
  TSUYOSHI Takato
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Identification of Selective Pluripotency Modulator of mesenchymal cells
- Principal Investigator
  
  SETO Ichiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
The development of temporomandibular joint reconstruction using auricular cartilage cells.
- Principal Investigator
  
  IINO Mitsuyoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Yamagata University
Novel therapeutic approaches to bone diseases using cell cycle factors Cdk4/6Principal Investigator
- Principal Investigator
  
  OGASAWARA Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Strategic research for the identification of novel osteogenic small compounds and their application to bone regeneration
- Principal Investigator
  
  MORI Yoshiyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Clarification of interaction between β-catenin and PTH in osteogenesis for craniofacial bone regeneration
- Principal Investigator
  
  KANNO Yuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
サイナスリフトに有効なテトラポッド形状人工骨の開発
- Principal Investigator
  
  大橋克巳
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Novel bone tissue engineering method using PTH signaling, its application to secondary alveolar bone grafting in patients with CLP and orthodontic evaluation
- Principal Investigator
  
  SUSAMI Takafumi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  The University of Tokyo
Strategic development of a novel implant system to achieve bone regeneration without cell transplantation
- Principal Investigator
  
  TAKATO Tsuyoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Where is the cause of Bartter's syndrome in the kidney?
- Principal Investigator
  
  WATANABE Sumiyo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Cyclooxygenase-2 Activity is Important in Fracture Healing of Membrane Bone
- Principal Investigator
  
  CHIKAZU Daichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
The analysis of the cell death control by CDK6
- Principal Investigator
  
  HARA Nobuhiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
3次元増殖培養装置と非侵襲評価装置の機能を有する軟骨再生のための新規足場素材の開発
- Principal Investigator
  
  高戸毅
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Development of cellular adhesion control type dental implant coated by biocompatible polymer
- Principal Investigator
  
  TOMIZUKA Ken
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  補綴理工系歯学
- Research Institution
  Niigata University
Research to enhance potentials of mesenchymal calls by introducing Nanog gene and its application to regenerative medicine of bone and cartilage
- Principal Investigator
  
  HOSHI Kazuto, 長谷川義道
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Bone regeneration for secondary bone graft and orthodontic evaluation
- Principal Investigator
  
  SUSAMI Takafumi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  The University of Tokyo
細胞周期関連分子Cdk6による骨代謝調節機構の解明-遺伝子操作マウスの解析-Principal Investigator
- Principal Investigator
  
  小笠原徹
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
細胞周期関連分子CDK6の生体内における骨・軟骨代謝調節機構の解明
- Principal Investigator
  
  KAWAGUCHI Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
コンピューター支援デザインによる積層造型法を応用した3次元再生骨構築法の確立
- Principal Investigator
  
  TAKATO Tsuyoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Research and Development for Fabrication of 3D-structured Tissue-engineered Cartilage through Nino-molecular Technologies
- Principal Investigator
  
  HOSHI Kazuto
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  The University of Tokyo
Regulation of Osseointegration by COX 2 : Molecular and Cellular biological Study
- Principal Investigator
  
  CHIKAZU Daichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Teeth eruption and movement in tissue-engineered bone
- Principal Investigator
  
  SUSAMI Takafumi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  The University of Tokyo
細胞周期関連分子CDK6による骨系統細胞分化制御機構に関する基礎的研究Principal Investigator
- Principal Investigator
  
  小笠原徹
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Analysis of expression pattern of fibrocartilage with a view to promoting regenerative medicine of temporomandibular joint
- Principal Investigator
  
  YODA Tetsuya
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical School

[Book] ほか注意すべき骨系統疾患患者が来院したら?医師・歯科医師のための口腔診療必携困ったときのマニュアル・ヒント集202, 1952010
- Author(s)
  小笠原徹
- Total Pages
  263
- Publisher
  高戸毅監修, 金原出版, 東京
- Data Source
  KAKENHI-PROJECT-22659365
[Book] 医師・歯科医師のための口腔診療必携2010
- Author(s)
  小笠原徹, ら
- Total Pages
  263
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-20592320
[Book] 注意すべき骨系統疾患患者が来院したら?医師・歯科医師のための口腔診療必携困ったときのマニュアル・ヒント集2022010
- Author(s)
  小笠原徹, 他
- Total Pages
  263
- Publisher
  金原出版株式会社
- Data Source
  KAKENHI-PROJECT-22659365
[Journal Article] Application of Dental Pulp Stem Cells for Bone and Neural Tissue Regeneration in Oral and Maxillofacial Region.2023
- Author(s)
  Fujii Y, Hatori A, Chikazu D, Ogasawara T.
- Journal Title
  
  Stem Cells Int.
  
  Volume: 2023 Pages: 2026572-2026572
- DOI
  10.1155/2023/2026572
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19746, KAKENHI-PROJECT-20H03884
[Journal Article] LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells.2020
- Author(s)
  Kitano J F V, Ohyama Y, Hayashida C, Ito J, Okayasu M, Sato T, Ogasawara T, Tsujita M, Kakino A, Shimada J, Sawamura T, and Hakeda Y.
- Journal Title
  
  Journal of Cell Science
  
  Volume: ー
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05505
[Journal Article] Application of Stem Cells in the Oral and Maxillofacial Region2020
- Author(s)
  Ogasawara Toru、Ko Edward Chengchuan、Yu Jiashing
- Journal Title
  
  Stem Cells International
  
  Volume: 2020 Pages: 1-2
- DOI
  10.1155/2020/2421453
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19746, KAKENHI-PROJECT-16H05538
[Journal Article] Lectin-like oxidized low-density lipoprotein receptor-1 abrogation causes resistance to inflammatory bone destruction in mice, despite promoting osteoclastogenesis in the steady state.2015
- Author(s)
  Nakayachi M, Ito J, Hayashida C, Ohyama Y, Kakino A, Okayasu M, Sato T, Ogasawara T, Kaneda T, Suda N, Sawamura T, Hakeda Y
- Journal Title
  
  Bone. 75:170-182
  
  Volume: 75 Pages: 170-182
- DOI
  10.1016/j.bone.2015.02.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24659916, KAKENHI-PROJECT-25293422, KAKENHI-PROJECT-26870540, KAKENHI-PROJECT-26463085, KAKENHI-PROJECT-15K15759, KAKENHI-PROJECT-26670895, KAKENHI-PROJECT-25293376
[Journal Article] Runx1 and Runx3 Are Downstream Effectors of Nanog in Promoting Osteogenic Differentiation of the Mouse Mesenchymal Cell Line C3H10T1/22015
- Author(s)
  Saito T, Ohba S, Yano F, Seto I, Yonehara Y, Takato T, Ogasawara T
- Journal Title
  
  Cell Reprogram
  
  Volume: 17 Issue: 3 Pages: 227-234
- DOI
  10.1089/cell.2014.0059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-25670846, KAKENHI-PROJECT-24390450, KAKENHI-PROJECT-26713054, KAKENHI-PROJECT-25713052
[Journal Article] 顎顔面領域における骨・軟骨再生に関する基礎および臨床研究2014
- Author(s)
  高戸毅、藤原夕子、星和人、小笠原徹、西條英人、安部貴大、阿部雅修、末永英之、菅野勇樹、杉山円、森良之
- Journal Title
  
  日本口腔科学会雑誌
  
  Volume: 第63巻2号 Pages: 207-215
- NAID
  130004781809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463069
[Journal Article] Cell cycle control factors and skeletal development2013
- Author(s)
  Toru Ogasawara
- Journal Title
  
  The Japanese Dental Science Review
  
  Volume: 49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659365
[Journal Article] Involvements of runt-related transcription factor 2 with cell-cycle machinery in osteoblasts and skeletal development: a review of the literature2013
- Author(s)
  Toru Ogasawara
- Journal Title
  
  Hard Tissue
  
  Volume: 2 Pages: 29-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390450
[Journal Article] Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP)signaling2013
- Author(s)
  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, Hoshi K.
- Journal Title
  
  J Cell Physiol
  
  Volume: 228(1) Pages: 163-71
- Data Source
  KAKENHI-PROJECT-23592912
[Journal Article] Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein (BMP) signaling2013
- Author(s)
  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, Hoshi K
- Journal Title
  
  J Cell Physiol
  
  Volume: 228(1) Pages: 163-171
- Data Source
  KAKENHI-PROJECT-23390459
[Journal Article] Cell cycle control factors and skeletal development2013
- Author(s)
  Toru Ogasawara
- Journal Title
  
  The Japanese Dental Science Review
  
  Volume: 49 Issue: 2 Pages: 79-87
- DOI
  10.1016/j.jdsr.2013.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390450
[Journal Article] Nanog promotes osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2 by modulating bone morphogenetic protein(BMP) signaling.2013
- Author(s)
  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Chung UI, Saito T, Yonehara Y, Nakatsuka T, Mori Y, Takato T, and Hoshi K
- Journal Title
  
  J Cell Physiol
  
  Volume: (in press) Issue: 1 Pages: 163-71
- DOI
  10.1002/jcp.24116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249056, KAKENHI-PROJECT-22659365, KAKENHI-PROJECT-22689052, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23390460, KAKENHI-PROJECT-23592913, KAKENHI-PROJECT-23659938, KAKENHI-PROJECT-24390451, KAKENHI-PROJECT-24593050, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25670847
[Journal Article] Role of cyclin-dependent kinase (Cdk)6 in osteoblast, osteoclast, and chondrocyte differentiation and its potential as a target of bone regenerative medicine2011
- Author(s)
  Toru Ogasawara, Yoshiyuki Mori, Masanobu Abe, Hideyuki Suenaga, Yoko Kawase-Koga, Hideto Saijo, Tsuyoshi Takato
- Journal Title
  
  Oral Science International
  
  Volume: 8 Issue: 1 Pages: 2-6
- DOI
  10.1016/s1348-8643(11)00007-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791973, KAKENHI-PROJECT-22659365
[Journal Article] Cyclooxygenase-2 activity is important in craniofacial fracture repair2011
- Author(s)
  Chikazu D, Fujikawa Y, Fujihara H, Suenaga H, Saijo H, Ohkubo K, Ogasawara T, Mori Y, Iino M, Takato T
- Journal Title
  
  Int J Oral Maxillofac Surg.
  
  Volume: 40 Issue: 3 Pages: 322-326
- DOI
  10.1016/j.ijom.2010.10.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791973, KAKENHI-PROJECT-22659365, KAKENHI-PROJECT-23593016
[Journal Article] Tumor-induced osteomalacia associated with a maxillofacial tumor producing fibroblast growth factor 23 : report of a case and review of the literature.2010
- Author(s)
  Mori Y, Ogasawara T, Motoi T, Shimizu Y, Chikazu D, Tamura K, Fukumoto S, Takato T.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 109(3)
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592320
[Journal Article] The optimization of porous polymeric scaffolds for chondrocyte/atelocollagen based tissue-engineered cartilage2010
- Author(s)
  Tanaka Y, Yamaoka H, Nishizawa S, Nagata S, Ogasawara T, Asawa Y, Fujihara Y, Takato T, Hoshi K.
- Journal Title
  
  Biomaterials 31(16)
  
  Pages: 4506-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Tumor-induced osteomalacia associated with a maxillofacial tumor producing fibroblast growth factor 23 : report of a case and review of the literature2010
- Author(s)
  Mori Y, Ogasawara T, et.al.
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Tumor-induced osteomalacia associated with a maxillofacial tumor producing fibroblast growth factor 23 : report of a case and review of the literature.2010
- Author(s)
  Mori Y, Ogasawara T, Motoi T, Shimizu Y, Chikazu D, Tamura K, Fukumoto S, Takato T
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 109(3)
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390509
[Journal Article] Effects of transforming growth factor (TGF)-β1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine.2009
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  Asian J Oral Maxillofac Surg (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Aptitude of auricular and nasoseptal chondrocytes cultured under a monolayer or three-dimensional condition for cartilage tissue engineering.2009
- Author(s)
  Asawa Y, Ogasawara T, Takahashi T, Yamaoka H, Nishizawa S, Matsudaira K, Mori Y, Takato T, Hoshi K.
- Journal Title
  
  Tissue Eng Part A. 15(5)
  
  Pages: 1109-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, et.al.
- Journal Title
  
  PLoS One. 4(2)(Epub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Transforming growth factor-β1 in combination with fibroblast growth factor-2 and insulin-like growth factor-I for chondrocyte proliferation culture and cartilage regenerative medicine.2009
- Author(s)
  Ogasawara T, Ohba S, Fujihara Y, Takahashi T, Liu G, Chikazu D, Suenaga H, Chung UI, Yoda T, Mori Y, Susami T, Takato T, Hoshi K.
- Journal Title
  
  Asian J Oral Maxillofac Surg 21
  
  Pages: 18-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] Screening of chondrogenic factors with a real-time fluoresce nce-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor2009
- Author(s)
  Kan A, Ikeda T, Ogasawara T., et.al
- Journal Title
  
  Arthritis Rheum. Nov ; 60(11)
  
  Pages: 3314-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Screening of chondrogenic factors with a real-time fluorescence-monitoring cell line ATDC5-C2ER : identification of sorting nexin 19 as a novel factor.2009
- Author(s)
  Kan A, Ikeda T, Saito T, Yano F, Fukai A, Hojo H, Ogasawara T, Ogata N, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  Arthritis Rheum. 60(11)
  
  Pages: 3314-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] Aptitude of auricular and nasoseptal chondrocytes cultured under a monolayer or three-dimensional condition for cartilage tissue engineering2009
- Author(s)
  Asawa Y, Ogasawara T, et.al.
- Journal Title
  
  Tissue Eng Part A 15(5)
  
  Pages: 1109-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Transforming Growth Factor-β1 in Combination with Fibroblast Growth Factor-2 and Insulin-like Growth Factor-I for Chondrocyte Proliferation Culture and Cartilage Regenerative Medicine.2009
- Author(s)
  Ogasawara T, Ohba S, Fujihara Y, Takahashi T, Liu G, Chikazu D, Suenaga H, Chung UI, Yoda T, Mori Y, Susami T, Takato T, Hoshi K.
- Journal Title
  
  Asian J Oral Maxillofac Surg. 21
  
  Pages: 18-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592320
[Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p572009
- Author(s)
  Hirata M, Ogasawara T, Ikeda T, et.al
- Journal Title
  
  PLoS One. 4(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57.2009
- Author(s)
  Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H.
- Journal Title
  
  PLoS One. 4(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] Aptitude of Auricular and Nasoseptal Chondrocytes Cultured under a Monolayer or Three-Dimensional Condition for Cartilage Tissue Engineering2009
- Author(s)
  Asawa, Y., Ogasawara, T., Takahashi, T., Yamaoka, H., Nishizawa, S., Matsudaira, K., Mori, Y., Takato, T. and Hoshi, K.
- Journal Title
  
  Tissue Eng Part A
  
  Pages: 1109-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] C/EBPβ promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57Kip22009
- Author(s)
  Hirata M, Kugimiya F, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Fukai A, Ikeda T, Nakamura K, Chung UI, and Kawaguchi H.
- Journal Title
  
  PLoS ONE 4(2)
  
  Pages: 4543-4543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Transforming Growth Factor-ss1 in Combination with Fibroblast Growth Factor-2 and Insulin-like Growth Factor-I for Chondrocyte Proliferation Culture and Cartilage Regenerative Medicine.2009
- Author(s)
  Ogasawara T, et al.
- Journal Title
  
  Asian J Oral Maxillofac Surg. 21
  
  Pages: 18-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] Effects of transforming growth factor (TGF)-β1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine.2009
- Author(s)
  Ogasawara T et al.
- Journal Title
  
  Asian J Oral Maxillofac Surg (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592387
[Journal Article] Effects of transforming growth factor (TGF)-β1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine.2009
- Author(s)
  Ogasawara T et al.
- Journal Title
  
  Asian J Oral Maxillofac Surg(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17791438
[Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008
- Author(s)
  Kawasaki, Y., Kugimiya, F., Chikuda, H., Kamekura, S., Ikeda, T., Kawamura, N., Saito, T., Shinoda, Y., Higashikawa, A., Yano, F., Ogasawara, T., Ogata, N., Hoshi, K., Hofmann, F., Woodgett, J.R., Nakamura, K., Chung, U.I. and Kawaguchi, H.
- Journal Title
  
  J Clin Invest 118
  
  Pages: 2506-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Growth Factor Contents of Autologous Human Sera Prepared by Different Production Methods and Their Biological Effects on Chondrocytes2008
- Author(s)
  Tanaka, Y., Ogasawara, T., Asawa, Y., Yamaoka, H., Nishizawa, S., Mori, Y., Takato. T., and Hoshi, K.
- Journal Title
  
  Cell Biology International (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Journal Article] Growth factor contents of autologous human sera prepared by different production methods and their biological effects on chondrocytes2008
- Author(s)
  Tanaka, Y., Ogasawara, T., Asawa, Y., Yamaoka, H., Nishizawa, S., Mori, Y., Takato, T. and Hoshi, K.
- Journal Title
  
  Cell Biol Int 32
  
  Pages: 505-514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Effects of transforming growth factor (TGF)-β1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine2008
- Author(s)
  Toru Ogasawara et al.,
- Journal Title
  
  Asian J Oral Maxillofac Surg (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592320
[Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba S, Kawaguchi H, Kugimiya F, Ogasawara T, Kawamura N, Saito T, Ikeda T, et.al.
- Journal Title
  
  Dev Cell. 14(5)
  
  Pages: 689-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Patchedl haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba, S., Kawaguchi, H., Kugimiya, F., Ogasawara, T., Kawamura, N., Saito, T., Ikeda, T., Fujii, K., Miyajima, T., Kuramochi, A., Miyashita, T., Oda, H., Nakamura, K., Takato, T., Chung, U.I.
- Journal Title
  
  Dev Cell 14
  
  Pages: 689-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390509
[Journal Article] Patched1 haploinsufficiency increases adult bone mass and modulates Gli3 repressor activity2008
- Author(s)
  Ohba, S., Kawaguchi, H., Kugimiya, F., Ogasawara, T., Kawamura, N., Saito, T., Ikeda, T., Fujii, K., Miyajima, T., Kuramochi, A., Miyashita, T., Oda, H., Nakamura, K., Takato, T. and Chung, U.I.
- Journal Title
  
  Dev Cell 14
  
  Pages: 689-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Growth factor contents of autologous human sera prepared by different production methods and their biological effects on chondrocytes2008
- Author(s)
  Tanaka Y, Ogasawara T, et.al.
- Journal Title
  
  Cell Biol Int. 32(5)(Epub)
  
  Pages: 505-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Phosphorylation of GSK-3beta by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes2008
- Author(s)
  Kawasaki Y, Kugimiya F, Chikuda H, Kamekura S, Ikeda T, Kawamura N, Saito T, Shinoda Y, Higashikawa A, Yano F, Ogasawara T, et.al.
- Journal Title
  
  J Clin Invest. 118(7), Erratum in 118(8)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Cyclooxygenase-2 Activity is essential for the Osseointegration of Dental Implants2007
- Author(s)
  Chikazu D., Tomizuka K., Ogasawara T., Saijo H., Koizumi T., Mori Y., Yonehara Y., Susami T. and Takato T.
- Journal Title
  
  Int J Oral Maxillofac Surg 36
  
  Pages: 441-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes2007
- Author(s)
  Liu G., Kawaguchi H., Ogasawara T., Asawa Y., Kishimoto J.I., Takahashi T., Chung U.I., Yamaoka H., Asato H., Nakamura K., Takato T. and Hoshi K.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 20407-20415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes2007
- Author(s)
  Liu, G., Kawaguchi, H., Ogasawara, T., Asawa, Y., Kishimoto, J. I., Takahashi, T., Chung, U. I., Yamaoka, H., Asato, H., Nakamura, K., Takato. T. and Hoshi. K.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 20407-20415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Journal Article] Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture2007
- Author(s)
  Takahashi T, Ogasawara T, et.al.
- Journal Title
  
  Tissue Eng. 13(7)
  
  Pages: 1583-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture2007
- Author(s)
  Takahashi T., Ogasawara T., Asawa Y., Mori Y., Uchinuma E., Takato T. and Hoshi K.
- Journal Title
  
  Tissue Engineering 13
  
  Pages: 1583-1592
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Cyclooxygenase-2 Activity is essential for the Osseointegration of Dental Implants2007
- Author(s)
  Chikazu, D., Tomizuka, K., Ogasawara, T., Saijo, H., Koizumi, T., Mori, Y., Yonehara, Y., Susami, T. and Takato, T.
- Journal Title
  
  Int J Oral Maxillofac Surg 36
  
  Pages: 441-446
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Journal Article] Optimal combination of soluble factors for tissue engineering of permanent cartilage from cultured human chondrocytes2007
- Author(s)
  Liu G, Kawaguchi H, Ogasawara T, et.al.
- Journal Title
  
  J Biol Chem. 282(28)(Epub)
  
  Pages: 20407-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590936
[Journal Article] Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture2007
- Author(s)
  Takahashi, T., Ogasawara, T., Asawa, Y., Mori, Y., Uchinuma, E., Takato, T. and Hoshi. K.
- Journal Title
  
  Tissue Engineering 13
  
  Pages: 1583-1592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Journal Article] Yonehara Cyclooxygenase-2 activity is essential for the osseointegration of dental implants2007
- Author(s)
  Chikazu D., Tomizuka K., Ogasawara T., Saijo H., Koizumi T., Mori Y.
- Journal Title
  
  Int.J.Oral.Maxillofac.Surg. 36
  
  Pages: 441-446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390509
[Journal Article] Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials2006
- Author(s)
  Yamaoka, H., Asato, H., Ogasawara, T., Nishizawa, S., Takahashi, T., Nakatsuka, T., Koshima, I., Nakamura, K., Kawaguchi, H., Chung, U-I, Takato, T., and Hoshi K
- Journal Title
  
  J Biomed Mater Res A 78
  
  Pages: 1-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Journal Article] Suppression of Adjuvant-Induced Arthritic Bone Destruction by Cyclooxygenase-2 Selective Agents with and without InhibitoryPotency against Carbonic Anhydrase II.2006
- Author(s)
  Katagiri M., Ogasawara T., Hoshi K., Chikazu D., Kimoto A., Noguchi M., Sasamata M., Harada S., Akama H., Tazaki H., Chung U., Takato T., Nakamura K., Kawaguchi H.
- Journal Title
  
  J Bone Miner Res 21
  
  Pages: 219-227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials2006
- Author(s)
  Yamaoka, H., Asato, H., Ogasawara, T., Nishizawa, S., Takahashi, T., Nakatsuka, T., Koshima, I., Nakamura, K., Kawaguchi, H., Chung, U-I, Takato, T., Hoshi K.
- Journal Title
  
  J Biomed Mater Res (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Combination of platelet-rich plasma and cyclooxygenase-2 inhibitor potently stimulates bone marrow stromal cell proliferation in vivo.2005
- Author(s)
  Chikazu, D., Ohba, S., Ogasawara, T., Saijo, H., Mori, Y., Tomizuka, K., Kawaguchi, H, Yonehara, Y., Susami, T., Takato, T.
- Journal Title
  
  Asian J Oral Maxillofac Snug 17(2)
  
  Pages: 81-87
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Inhibition of Cdk6 expression through p38 MAP kinase is involved in differentiation of mouse prechondrocyte ATDC5.2005
- Author(s)
  Moro, T., Ogasawara, T., Chikuda, H., Ikeda, T., Ogata, N., Maruyama, Z., Komori, T., Hoshi, K., Chung, U.I., Nakamura, K, Okayama, H., Kawaguchi, H.
- Journal Title
  
  J Cell Physiol 204
  
  Pages: 927-933
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.2005
- Author(s)
  Yano, F., Kugimiya, F., Ohba, S., Ikeda, T., Chikuda, H., Ogasawara, T., Ogata, N., Takato, T., Nakamura, K., Kawaguchi, H., Chung, U.I.
- Journal Title
  
  Biochem Biophys Res Commun 333
  
  Pages: 1300-1308
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Mutation in cGMP-dependent protein kinase IIcauses dwarfism in a rat mutant KMI through uncoupling of proliferation and differentiation of chondrocytes.2005
- Author(s)
  Chikuda, H., Kugimiya, F., Hoshi, K., Ikeda, T., Ogasawara, T., Kamekura, S., Ogata, N., Nakamura, K., Chung, U.I., Kawaguchi, H.
- Journal Title
  
  J Bone Miner Metab 23
  
  Pages: 200-204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Synergistic effects of FGF-2 with insulin or IGF-I on the proliferation of human auricular chondrocytes.2005
- Author(s)
  Takahashi, T., Ogasawara, T., Kishimoto, J., Liu, G., Asato, H., Nakatsuka, T., Uchinuma, E., Nakamura, K., Kawaguchi, H., Takato, T., Hoshi, K.
- Journal Title
  
  Cell Transplant 14
  
  Pages: 683-693
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes.2004
- Author(s)
  Chikuda, H., Kugimiya, F., Hoshi, K., Ikeda, T., Ogasawara, T., Shimoaka, T., Kawano, H., Kamekura, S., Tsuchida, A., Yokoi, N., Nakamura, K., Komeda, K, Chung, U.I., Kawaguchi, H.
- Journal Title
  
  Genes Dev 18
  
  Pages: 2418-2429
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Data Source
  KAKENHI-PROJECT-15791158
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Ogasawara, T., et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regrulation of Cdk6.2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004
- Author(s)
  Ogasawara, T., et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6(Cdk6).2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6(Cdk6).2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004
- Author(s)
  Ogasawara T, et al.
- Journal Title
  
  Journal of Bone and Mineral Research 19
  
  Pages: 1128-1136
- Data Source
  KAKENHI-PROJECT-16659402
[Journal Article] Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).2004
- Author(s)
  Ogasawara, T., Katagiri, M., Yamamoto, A., Hoshi, K., Takato, T., Nakamura, K., Tanaka, S., Okayama, H., Kawaguchi, H.
- Journal Title
  
  J Bone Miner Roe 19
  
  Pages: 1128-1136
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Data Source
  KAKENHI-PROJECT-15791158
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Toru Ogasawara et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592098
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires smad-mediated down-regulation of cdk6.2004
- Author(s)
  Ogasawara T, et al.
- Journal Title
  
  Molecular Cell Biology 24
  
  Pages: 6560-6568
- Data Source
  KAKENHI-PROJECT-16659402
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Ogasawara T. et al.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6.2004
- Author(s)
  Ogasawara, T., Kawaguchi, H., Jinno, S., Hoshi, K., Itaka, K., Takato, T., Nakamura, K., Okayama, H.
- Journal Title
  
  Mol Cell Biol 24
  
  Pages: 6560-6568
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Osteoclast differentiation by RANKL requires NF-κB-mediated downregulation of cyclin-dependent kinase 6(Cdk6).2004
- Author(s)
  Ogasawara T. et al.
- Journal Title
  
  J Bone Miner Res 19
  
  Pages: 1128-1136
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16592039
[Journal Article] Selection of highly osteogenic and chondrogenic cells from bone marrow stromal cells in biocompatible polymer-coated plates
- Author(s)
  Liu G., Iwata K., Ogasawara T,, Watanabe J., Fukazawa K., Ishihara K., Asawa Y., Fujihara Y., Chung U.I., Moro T., Takatori Y., Takato T. Nakamura K., Kawaguchi H., and Hoshi K.
- Journal Title
  
  J Biomed Mater Res A (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Effects of transforming growth factor (TGF)-β1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine
- Author(s)
  Ogasawara T,, Ohba S., Fujihara Y., Takahashi T., Liu G., Chikazu D., Suenaga H., Chung U.I., Yoda T., Mori Y., Susami T., Takato T., and Hoshi K.
- Journal Title
  
  Asian J Oral Maxillofac Surg (in press)
- Data Source
  KAKENHI-PROJECT-18591654
[Journal Article] Effects of transforming growth factor (TGF)-b1 in combination with fibroblast growth factor (FGF)-2 and insulin-like growth factor (IGF)-I on chondrocytes proliferation culture for the cartilage regenerative medicine
- Author(s)
  Ogasawara T. et al
- Journal Title
  
  Asian J Oral Maxillofac Surg (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592368
[Presentation] 滑膜細胞増殖を標的とした関節リウマチ治療におけるCDK6単独阻害の可能性．2023
- Author(s)
  藤井　亮爾, 小松　梨恵, 鈴木　由妃, 小笠原　徹ほか
- Organizer
  第38回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-20H03884
[Presentation] Highly efficient differentiation of chondrocytes from human dental pulp stem cells using a thienoindazole derivative small compound TD-198946.2022
- Author(s)
  Kanno Y, Ogasawara T et al.
- Organizer
  ASBMR 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19746
[Presentation] VCAM-1 and GFPT-2: Predictive markers of osteoblast differentiation in human dental pulp stem cells.2022
- Author(s)
  Hatori A, Ogasawara T et al.
- Organizer
  ASBMR 2022 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19746
[Presentation] ホメオボックス転写因子Nanogは間葉系細胞の骨軟骨分化において重要である2020
- Author(s)
  小笠原　徹
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K19746
[Presentation] Nanogは間葉系細胞の骨軟骨分化において重要である.2020
- Author(s)
  小笠原　徹
- Organizer
  第74回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05538
[Presentation] ホメオボックス転写因子Nanogは間葉系細胞の骨軟骨分化において重要である2020
- Author(s)
  小笠原徹
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20H03884
[Presentation] ホメオボックス転写因子Nanogは間葉系細胞の骨軟骨分化において重要である.2020
- Author(s)
  小笠原　徹
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05538
[Presentation] CyclinD1はNanogが有する間葉系細胞骨軟骨分化能促進効果のバランスを制御する2017
- Author(s)
  小笠原　徹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-25670846
[Presentation] CyclinD1はNanogが有する間葉系細胞骨軟骨分化能促進効果のバランスを制御する.2017
- Author(s)
  小笠原　徹
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-16H05538
[Presentation] CyclinD1 regulates the balance between the osteogenic and chondrogenic differentiation of mesenchymal cells that constitutively express Nanog.2016
- Author(s)
  Toru Ogasawara, Jumpei Imamura, Yasuyuki Fujii
- Organizer
  ASBMR 2016 Annual Meeting
- Place of Presentation
  Atlanta, Georgia, USA, Georgia World Congress Center
- Year and Date
  2016-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670846
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells.2014
- Author(s)
  Toru Ogasawara et al.
- Organizer
  2013 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, Maryland, USA, Baltimore Convention Center
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells2013
- Author(s)
  Ogasawara T, Saito T, Ohba S, Abe T, Yonehara Y, Takato T.
- Organizer
  2013 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, Maryland, USA, Baltimore Convention Center
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells.2013
- Author(s)
  Toru Ogasawara et al.
- Organizer
  2013 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, Maryland, USA, Baltimore Convention Center
- Data Source
  KAKENHI-PROJECT-25670846
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells.2013
- Author(s)
  Ogasawara T, Saito T, Ohba S, Abe T, Yonehara Y, Takato T
- Organizer
  35th Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, MD, USA
- Data Source
  KAKENHI-PROJECT-23390460
[Presentation] Nanogの間葉系細胞骨分化能促進効果に関与する下流分子の網羅的探索2013
- Author(s)
  小笠原徹,　斎藤忠仁,　大庭伸介,　米原啓之,　星和人,　高戸毅
- Organizer
  第12回　日本再生医療学会総会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells2013
- Author(s)
  Ogasawara T, Saito T, Ohba S, Abe T, Yonehara Y, Takato T:
- Organizer
  The 35th ASBMR Annual Meeting
- Place of Presentation
  Baltimore Convention Center, Discovery Hall-Hall C, Baltimore, Maryland USA
- Data Source
  KAKENHI-PROJECT-25463069
[Presentation] Nanogの間葉系細胞骨分化能促進効果に関与する下流分子の網羅的探索2013
- Author(s)
  小笠原徹, 斎藤忠仁, 大庭伸介, 米原啓之, 星和人, 高戸毅
- Organizer
  第12回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜会議センター, 神奈川
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Need for orthognathic sugery and its prediction in early mixed dentition in patients with bilateral cleft lip and palate.2013
- Author(s)
  Okayasu M , Susami T , Inocuchi T , Ohkubo K , Uchino N , Uwatoko K , Ogasawara T , Ssaijo H , Mori Y , Takato T
- Organizer
  12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-23390459
[Presentation] Runx1 and Runx3 are downstream effectors of Nanog in the promoted osteogenic differentiation of mesenchymal cells.2013
- Author(s)
  Toru Ogasawara et al.
- Organizer
  2013 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore, Maryland, USA, Baltimore Convention Cente
- Data Source
  KAKENHI-PROJECT-24390450
[Presentation] Palatal index for evaluation of the palatal morphology in patients with uniateral cleft lip and palate2013
- Author(s)
  Inokuchi T, Susami T, Okayasu M, Uchino N, Uwatoko K, Ohkubo K, Ogasawara T, Saijo H, Mori Y, Takato T
- Organizer
  12th International Congress on Cleft Lip/Palate and Related Craniofacial Anomalies
- Place of Presentation
  Florida, USA
- Data Source
  KAKENHI-PROJECT-23390459
[Presentation] Nanogの間葉系細胞骨分化能促進効果はBMPシグナルとの相互作用とNFATc1の誘導を介する2012
- Author(s)
  小笠原徹,　大庭伸介,　矢野文子,　斎藤忠仁,　瀬戸一郎,　米原啓之,　森良之,　星和人,　高戸毅
- Organizer
  第57回（公社）日本口腔外科学会総会・学術集会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Nanogの間葉系細胞骨分化能促進効果はBMPシグナルとの相互作用とNFATc1の誘導を介する2012
- Author(s)
  小笠原徹, 大庭伸介, 矢野文子, 斎藤忠仁, 瀬戸一郎, 米原啓之, 森良之, 星和人, 髙戸毅
- Organizer
  第57回(公社)日本口腔外科学会総会・学術集会
- Place of Presentation
  パシフィコ横浜会議センター, 神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Nanogの間葉系細胞骨分化能促進効果はBMPシグナルとの相互作用とNFATc1の誘導を介する.2012
- Author(s)
  小笠原徹
- Organizer
  第57回日本口腔外科学会総会・学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23390459
[Presentation] Nanog promotes osteogenic differentiation of mesenchymal cells by modulating bone morphogenetic protein (BMP) signaling.2011
- Author(s)
  Toru Ogasawara et al.
- Organizer
  2011 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, California,USA
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Nanog promotes osteogenic differentiation of mesenchymal cells by modulating bone morphogenetic protein (BMP)signaling2011
- Author(s)
  Ogasawara T, Ohba S, Yano F, Kawaguchi H, Abe T, Takato T, Hoshi K.
- Organizer
  2011 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, California, USA, San Diego Convention Center
- Data Source
  KAKENHI-PROJECT-23592912
[Presentation] Nanog promotes osteogenic differentiationof mesenchymal cells by modulating bonemorphogenetic protein (BMP) signaling.2011
- Author(s)
  Ogasawara T, Ohba S, Yano F, KawaguchiH, Abe T, Takato T, Hoshi K
- Organizer
  2011 annual meeting of the AmericanSociety for Bone and Mineral ResearchSeptember 17
- Place of Presentation
  San Diego, California,USA
- Data Source
  KAKENHI-PROJECT-22659365
[Presentation] Nanog promotes osteogenic differentiation of mesenchymal cells by modulating bone morphogenetic protein (BMP) signaling2011
- Author(s)
  Toru Ogasawara, et al.
- Organizer
  2011 annual meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22659365
[Presentation] 間葉系細胞において Nanog は BMP シグナルを増強する2010
- Author(s)
  斎藤忠仁 , 小笠原徹 , 森良之, 近津大地, 阿部雅修 , 末永英之, 白土博司, 高戸毅, 米原啓之
- Organizer
  第64回日本口腔科学会学術集会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-22659365
[Presentation] 間葉系細胞においてNanogはBMPシグナルを増強する2010
- Author(s)
  斎藤忠仁, 小笠原徹, 他
- Organizer
  第64回日本口腔科学会学術集会
- Place of Presentation
  札幌プリンスホテル北海道札幌市
- Data Source
  KAKENHI-PROJECT-22659365
[Presentation] 細胞周期制御を利用した骨粗鬆症治療法開発のための基礎的検討2009
- Author(s)
  小笠原徹,高戸毅
- Organizer
  第9回日本抗加齢医学会総会
- Place of Presentation
  ホテル日航東京,東京
- Data Source
  KAKENHI-PROJECT-20592320
[Presentation] 間葉系細胞の分化多能性維持機構におけるNanogの役割2009
- Author(s)
  小笠原徹ほか
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪府大阪市
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] 細胞周期制御を利用した骨粗鬆症治療法開発のための基礎的検討2009
- Author(s)
  小笠原徹, 高戸毅
- Organizer
  第9回日本抗加齢医学会総会
- Place of Presentation
  東京都港区
- Data Source
  KAKENHI-PROJECT-20592387
[Presentation] 間葉系細胞の分化多能性維持機構におけるNanog の役割2008
- Author(s)
  小笠原徹, 川口浩, 高戸毅, 星和人
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場大阪
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] 間葉系細胞の分化多能性維持機構におけるNanogの役割2008
- Author(s)
  小笠原徹, 川口浩, 高戸毅, 星和人
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪府大阪市
- Data Source
  KAKENHI-PROJECT-20592387
[Presentation] 間葉系細胞の分化多能性維持機構におけるNanogの役割2008
- Author(s)
  小笠原徹, ほか
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪府大阪市
- Data Source
  KAKENHI-PROJECT-17791438
[Presentation] 問葉系細胞の分化多能性維持機構におけるNanogの役割2008
- Author(s)
  小笠原徹ほか
- Organizer
  第26回日本骨代謝学会学術集会
- Place of Presentation
  大阪府大阪市
- Data Source
  KAKENHI-PROJECT-20592387
[Presentation] Tissue reactions around the tissue-engineered cartilage based on biopolymers2007
- Author(s)
  Fujihara Y., Ogasawara T., Asawa Y., Fujihara H., Takato T., Hoshi K.
- Organizer
  2007 TERMIS-EU Chapter Meeting
- Place of Presentation
  London.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Cytological roles of the FGF family in the chondrocyte redifferentiation2007
- Author(s)
  Nishizawa S., Yamaoka H., Ogasawara T., Asawa Y., Yamaoka K., Takato T., Hoshi K.
- Organizer
  Tissue Engineering International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Cytological roles of the FGF family in the chondrocyte redifferentiation2007
- Author(s)
  Nishizawa S., Yamaoka H., Ogasawara T., Asawa Y., Yamaoka K., Takato T., Hoshi K.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] ヒト軟骨細胞の継代培養に伴う表面抗原の変化とその生物学的意義2007
- Author(s)
  浅輪幸世, 小笠原徹, 高戸毅, 星和人
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Application of Cell Cycle Factors to Bone Regeneration.2007
- Author(s)
  Toru Ogasawara, et. al.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] A new thienoindazole derivative promotes chondrogenic differentiation via Runxl, co-activator of Sox5, Sox6 and Sox9(the Sox trio)2007
- Author(s)
  Yano F., Ikeda T., Saito T., Ogata N., Ogasawara T., Kimura A., Takeda S., Nakamura K., Kawaguchi H., Takato T., Chung UI.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] 細胞周期分子による骨再生医療のための基礎的検討2007
- Author(s)
  小笠原徹, ほか
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-03-13
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Examination of Scaffold System Suitable for Implant-type Tissue-engineered Cartilage2007
- Author(s)
  Tanaka Y., Yamaoka H., Nishizawa S., Ogasawara T., Fujihara Y., Asawa Y., Takato T., Hoshi K.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Changes in surface epitopes of human chondrocytes during a long-term culture and their biological significances2007
- Author(s)
  Asawa Y., Ogasawara T., Takato T., Hoshi K.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Application of cell cycle factors to bone regeneration2007
- Author(s)
  Ogasawara T., Hoshi K., Kawaguchi H., Ohba S., Chikazu D., Fujihara Y., Suenaga H., Mori Y., Susami T., Okayama H., Takato T.
- Organizer
  Tissue Engineering International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] 軟骨細胞脱分化現象におけるFGF ファミリーの役割2007
- Author(s)
  西澤悟, 山岡尚世, 小笠原徹, 浅輪幸世, 山岡桂子, 高戸毅, 星和人
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Minuscule Tetrapod-Shape Bone Filler2007
- Author(s)
  Igawa K., Tomizuka K., Ohba S., Ogasawara T., Chikazu D., Mori Y., Takato T., Chung U. I
- Organizer
  AAOMS 89th Annual Meeting, Scientific Sessions & Exhibition In conjunction with the JSOMS and KAOMS
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] 細胞周期分子による骨再生医療のための基礎的検討2007
- Author(s)
  小笠原徹ほか
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  神奈川県横浜市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592166
[Presentation] Application of Cell Cycle Factors to Bone Regeneration.2007
- Author(s)
  Toru Ogasawara, et. al.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Minuscule Tetrapod-Shape Bone Filler2007
- Author(s)
  Igawa K., Tomizuka K., Ohba S., Ogasawara T., Chikazu D., Mori Y., Takato T., Chung U. I.
- Organizer
  The 52nd Annual Meeting of the Japanese Society of oral and maxillofacial Surgeon
- Place of Presentation
  Nagoya.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Changes in surface epitopes of human chondrocytes during a long-term culture and their biological significances2007
- Author(s)
  Asawa Y., Ogasawara T., Takato T., Hoshi K.
- Organizer
  Tissue Engineering International & Regenerative Medicine Society Asia-Pacific Chapter Meeting 2007
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] 細胞周期分子による骨再生医療のための基礎的検討2007
- Author(s)
  小笠原徹, 川口浩, 岡山博人, 高戸毅, 星和人
- Organizer
  第6回日本再生医療学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Scaffold System Suitable for Implant-type - Tissue-engineered Cartilage2007
- Author(s)
  Tanaka Y., Yamaoka H., Nishizawa S., Ogasawara T., Fujihara Y., Asawa Y., Takato T., Hoshi K.
- Organizer
  7th annual meeting of the TERMIS-EU
- Place of Presentation
  London.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Assessment of the early-phase tissue reactions in the engineered cartilage based on biomaterials2007
- Author(s)
  Fujihara Y., Ogasawara T., Asawa Y., Fujihara H., Susami T., Takato T., Hoshi K.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Application of Cell Cycle Factors to Bone Regeneration2007
- Author(s)
  Ogasawara T., Hoshi K., Kawaguchi H., Ohba S., Chikazu D., Fujihara Y., Suenaga H., Mori Y., Susami T., Okayama H., Takato T.
- Organizer
  TERMIS-AP 2007
- Place of Presentation
  Tokyo.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Application of Cell Cycle Factors to Bone Regeneration.2007
- Author(s)
  Toru Ogasawara, et. al.
- Organizer
  TERMIS-AP meeting
- Place of Presentation
  Japan (Tokyo)
- Data Source
  KAKENHI-PROJECT-18592166
[Presentation] Growth Factor Contents of Autologous Human Sera Prepared by Different Production Methods and Their Biological Effects on Chondrocytes2006
- Author(s)
  Tanaka Y., Ogasawara T., Nishizawa S., Yamaoka H., Asawa Y., Takahashi T., Takato T., Hoshi K.
- Organizer
  The 5th Annual Meeting of the Japanese Society for Regenerative Medicine
- Place of Presentation
  Okayama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] 軟骨再生医療の軟骨細胞培養におけるTGF-βの効果について2006
- Author(s)
  小笠原徹ほか
- Organizer
  第5回日本再生医療学会総会
- Place of Presentation
  岡山県岡山市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592166
[Presentation] Statistical Optimization of Combinations of Clinically-available Soluble Factors for Cartilage Tissue Engineering2006
- Author(s)
  Hoshi K., Liu G., Ogasawara T., Takahashi T., Asawa Y., Yamaoka H., Chung UI., Kawaguchi H., Nakamura K., Takato T
- Organizer
  World Congress of Tissue Engineering and Regenerative Medicine
- Place of Presentation
  Pittsburg, Pennsylvania, USA.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Optimization of Combinations of bone formation signaling and development of bone regenerative medicine without stem cells2006
- Author(s)
  Ohba S., Yano F., Igawa K., Fujihara Y., Ogasawara T., Chikazu D., Mori Y., Yonehara Y., Susami T., Chung U. I., Takato T.
- Organizer
  The 60th Annual Meeting of the Japanese Stomatological Society
- Place of Presentation
  Nagoya.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] 軟骨再生医療の軟骨細胞培養におけるTGF-βの効用について2006
- Author(s)
  小笠原徹ほか
- Organizer
  第5回日本再生医療学会総会
- Place of Presentation
  岡山
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Growth and differentiation of human auricular and nasal chondrocytes2006
- Author(s)
  Asawa Y., Ogasawara T., Imura S., Chung UI., Takato T., Hoshi K.
- Organizer
  The 5th Annual Meeting of the Japanese Society for Regenerative Medicine
- Place of Presentation
  Okayama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] 自家軟骨細胞から大量永久軟骨再生のための最適シグナル条件の系統的・網羅的検索2006
- Author(s)
  星和人, 劉光耀, 小笠原徹, 浅輪幸世, 高橋嗣明, 鄭雄一, 高戸毅, 中村耕三, 川口浩
- Organizer
  第24回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] ptimal combination of soluble factors for Tissue Engineering of permanent cartilage with high quality and quantity from autologous human chondrocytes2006
- Author(s)
  Hoshi K, Liu G, Ogasawara T, Asawa Y, Takahashi T, Yamaoka H, Chung U, Takato T, Nakamura K, Kawaguchi H.
- Organizer
  Twenty-Eighth Annual Meeting of the American Society for Bone and Mineral Research September
- Place of Presentation
  Pennsylvania Convention Center Philadelphia, Pennsylvania, USA
- Data Source
  KAKENHI-PROJECT-18591654
[Presentation] Three-dimensional microenvironments retain chondrocyte phenotypes during proliferation culture2006
- Author(s)
  Takahashi T., Ogasawara T., Chung UI., Kawaguchi H., Nakamura K., Uchinuma E., Takato T., Hoshi K.
- Organizer
  The 5th Annual Meeting of the Japanese Society for Regenerative Medicine
- Place of Presentation
  Okayama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Cartilage tissue engineering using human auricular chondrocytes embedded in different hydrogel materials2006
- Author(s)
  Yamaoka H., Nishizawa S., Ogasawara T., Tanaka Y., Takato T., Hoshi K.
- Organizer
  The 5th Annual Meeting of the Japanese Society for Regenerative Medicine
- Place of Presentation
  Okayama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Effects of TGF-β over chondrocytes used for Cartilage Tissue Engineering2006
- Author(s)
  Ogasawara T., Takahashi T., Asawa Y., Yamaoka H., Tanaka Y., Nishizawa s., Liu G., Yoda T., Susami T., Takato T., Hoshi K.
- Organizer
  The 5th Annual Meeting of the Japanese Society for Regenerative Medicine
- Place of Presentation
  Okayama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18592231
[Presentation] Nanogの間葉系細胞骨分化能促進効果におけるRunxファミリー（Runx1/2/3）の関与
- Author(s)
  小笠原徹
- Organizer
  第68回NPO法人日本口腔科学会学術大会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-05-08 – 2015-05-09
- Data Source
  KAKENHI-PROJECT-25670846
[Presentation] 顎関節を初発部位とする早期関節リウマチに対してエタネルセプトを用いた1例
- Author(s)
  安部貴大，立石晶子，小宮山雄介，波田野典子，細川瑠美子，阿部雅修，小笠原徹，高戸毅
- Organizer
  第27回日本顎関節学会総会
- Place of Presentation
  福岡
- Year and Date
  2014-07-19 – 2014-07-20
- Data Source
  KAKENHI-PROJECT-25463069
[Presentation] Nanogの間葉系細胞骨分化能促進効果におけるRunxファミリー（Runx1/2/3）の関与
- Author(s)
  小笠原徹
- Organizer
  第68回NPO法人日本口腔科学会学術大会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2014-05-08 – 2014-05-09
- Data Source
  KAKENHI-PROJECT-24390450

1. ABE Masanobu (10392333)

# of Collaborated Projects: 11 results

# of Collaborated Products: 5 results
2. TAKATO Tsuyoshi (90171454)

# of Collaborated Projects: 10 results

# of Collaborated Products: 31 results
3. CHIKADU Daichi (30343122)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
4. ABE Takahiro (20383250)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
5. HOSHI Kazuto (30344451)

# of Collaborated Projects: 8 results

# of Collaborated Products: 25 results
6. MORI Yoshiyuki (70251296)

# of Collaborated Projects: 8 results

# of Collaborated Products: 4 results
7. OGATA Naoshi (10361495)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
8. TEI Yuichi (30345053)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
9. CHIKUDA Hirotaka (30345219)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
10. MORO Toru (20302698)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
11. YANO Fumiko (80529040)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
12. HAKEDA Yoshiyuki (90164772)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
13. KAWAGUCHI Hiroshi (40282660)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
14. UCHIDA Shunya (50151882)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. SAIJO Hideto (80372390)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
16. OHASHI Katsumi (60233235)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. SUSAMI Takafumi (80179184)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
18. TOMITSUKA Ken (80251297)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
19. WATANABE Sumiyo (30422314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
20. IKEDA Tosiyuki (80322759)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
21. ISHIHARA Kazuhiko (90193341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. NAKAMURA Kozo (60126133)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. FUJIHARA Yuko (50466744)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. INOKUCHI Takato (80587775)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
25. OKAYASU Mari (10610941)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
26. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
27. ITO Junta (40609096)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
28. HARA Nobuhiro (00422296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
29. FUKAI Atsushi (20422298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. KAWANO Hirotaka (20345218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. NISHIYAMA Nobuhiro (10372385)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. SAITO Taku (30456107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
33. SUZUKI Nobuchika (90247007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. HONDA Zenitiro (70238814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. KANNO Yuki (80451813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. OHKUBO Kazumi (10396715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. IINO Mitsuyoshi (50212717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. HAMAMOTO Yoshioki (40231526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. TAKATORI Yoshio (40179461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. KONNO Tomohiro (80371706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. HASHIMOTO Masami (20450851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. OSHIMA Hirofumi (00622359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. KATAOKA Kazunori (00130245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. SETO Ichiro (30582390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
45. KOGA Yoko (10392408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. OGAWA Takuya (50401360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. FUKUSHIMA Shigeto (60625680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
48. SATO Takuya (00316689)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
49. HAYASHIDA Chiyomi (40710900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. KANEDA Toshio (70339521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. YODA Tetsuya (60242210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. TOMARU Yasuhisa (50348207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
53. SHIMAMURA Yumiko (10348287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. ITAKA Keishi (60292926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. OGIHARA Yuji (20345226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. IWASAKI Yasuhiko (90280990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. MATSUZAKI Masako (80313154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. 小守壽文 (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. 岡山博人 (40111950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. 引地尚子 (50292876)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. 米原啓之 (00251299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. 井川和代 (90512111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. 長谷川義道 (20401119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. 森芳史 (60757954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. 野口忠秀 (30275705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. 土屋欣之 (00343442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
67. 細沼雅弘 (20836457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
68. 小俣康徳 (40570734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
69. 北條宏徳 (80788422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
70. 須田直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ogasawara Tohru 小笠原 徹

OGASAWARA Toru 小笠原 徹

Research Projects

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Co-Researchers

Cdk4/Cdk6による古典的細胞周期制御と転写制御の統合的理解による骨代謝機構の解明Principal Investigator

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Cdk6による骨格幹細胞G0/G1期制御機構の解明と骨再生医療に向けた基礎的検討Principal Investigator

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Identification of novel osteoclast-osteoblast coupling factors in exosomes involving cell cycle machineryPrincipal Investigator

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Identification of microRNAs controlled by Cdk6 for understanding of bone metabolism system and their application for regenerative medicinePrincipal Investigator

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Investigation of factors which simultaneously regulate bone formation and bone resorption in terms of cell cycle regulation.Principal Investigator

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Ogasawara Tohru 小笠原徹

OGASAWARA Toru 小笠原徹