Hirai Hirokazu 平井宏和

… Alternative Names

HIRAI Hirokazu 平井宏和

平井宏和ヒライヒロカズ

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Researcher Number	70291086
Other IDs
Affiliation (Current)	2025: 群馬大学, 大学院医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 群馬大学, 大学院医学系研究科, 教授 2014 – 2020: 群馬大学, 大学院医学系研究科, 教授 2014 – 2015: 群馬大学, 医学(系)研究科(研究院), 教授 2011: Gunma University, 医学(系)研究科(研究院), 教授 2006 – 2010: GUNMA UNIVERSITY, GRADUATE SCHOOL OF MEDICINE, PROFESSOR, 大学院・医学系研究科, 教授 … More 2007: 群馬大学, 医学(系)研究科(研究院), 教授 2006: 群馬大学, 大学院医学系研究科, 教授 2005: 金沢大学, 学際科学実験センター, 助教授 1997 – 2000: 理化学研究所, 記憶学習機構研究チーム, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Neuroscience in general / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 46010:Neuroscience-general-related / Neurology / Neurophysiology / General neuroscience / Neuroscience in general / Biological Sciences / Neurophysiology and muscle physiology / Neurochemistry/Neuropharmacology … More Except Principal Investigator … More Neurochemistry/Neuropharmacology / Neurophysiology / General neuroscience / Laboratory animal science / Radiation science / Biological Sciences / Neuroscience in general Less
Keywords	Principal Investigator 小脳 / プルキンエ細胞 / グルタミン酸受容体 / GluR2 / AAV / 脊髄小脳失調症 / トランスジェニックマウス / 運動失調 / 神経変性疾患 / 脊髄小脳変性症 … More / 遺伝子治療 / ウイルスベクター / 細胞種特異的プロモーター / 神経科学 / 遺伝子 / 脳神経疾患 / SCA1 / AAVベクター / デルタ2 / ポリグルタミン病 / mGluR1 / PKC / リン酸化 / ^<31>P-NMR / microRNA / 遺伝子発現 / マウス / 大脳皮質 / カプシド / Iba1 / アルツハイマー病 / 血液脳関門 / ミクログリア / シナプス可塑性 / floxマウス / Cre / レット症候群 / MeCP2 / 自閉症 / 再生医学 / アデノ随伴ウイルスベクター / ゲノム編集 / CRISPR/Cas9 / パッチクランプ / ロータロッド / 生理学 / シグナル伝達 / 運動記憶 / SCA3 / バクロフェン / 運動学習 / Cerebellum / Transgenic mouse / Glutamate receptor / Purkinje cell / 運動ニューロン / 細胞治療 / 間葉系幹細胞 / Staggerer / 神経再生 / 神経発達 / 神経発生 / 神経回路 / シナプス / ニューロン / 樹状突起 / レンチウイルス / CAGリピート / HEK / リン脂質代謝 / ディアシルグリセロール / フォスファチジルコリン / フォスフォリルコリン / 記憶 / LTD / NMR / 分子生物学 / 核磁気共鳴 / GST / AMPA受容体 … More Except Principal Investigator プルキンエ細胞 / 小脳 / モデル動物 / Hermansky-Pudlak Syndrome / 脊髄小脳変性症 / グリア / イオンチャネル / チャネル / 軸索側枝 / 抑制性シナプス伝達 / ランビエ絞輪 / 瞬目反射条件づけ / ペリニューロナルネット / 細胞外マトリックス / 小脳核 / BKチャネル / パラノード / 活動電位 / ATP受容体 / 二重感染 / AAV / ウイルスベクター / 脳分子プロファイル / 脳画像データベース / ブレインバンク / 技術開発支援 / 研究リソース支援 / 若手研究者育成支援 / 技術開発 / 研究リソース / 研究集会 / 研究支援 / 脳科学 / Mouse / Disease model animal / dilution of skin color / Coat color / Positional clonin / MutaReneis / Motor coodination / 連鎖解析 / 電気生理解析 / 染色体マッピング / 突然変異 / 運動失調 / マウス / 疾患モデル動物 / 皮膚の薄色化 / 毛色 / ポジショナルクローニング / ミュータジェネシス / 運動協調性 / 神経変性症 / 神経変性疾患 / NMDA受容体 / メマンチン / 脊髄小脳変性症1型 / ポリグルタミン病 / グルタミン酸貯留 / TBOA / スライスパッチクランプ / 痙攣 / 突起伸展 / GluR2 / 海馬 / 小脳皮質 / GLT-1 / GLAST / 小脳プルキンエ細胞 / 登上線維 / 興奮性シナプス伝達 / プリキンエ細胞 / Gfa2プロモーター / ベルクマングリア / グルタミン酸作動性シナプス / トランスポーター電流 / 興奮性シナプス後電流 / 小脳ベルクマングリア / グリアーニューロン機能連関 / グルタミン酸トランスポーター / AMPA受容体 / プロテアソーム / カルパイン / 記憶学習 / プロテアーゼ / 学習 / 記憶 Less

Development of microglia-targeting AAV vectors and its application to neurodegenerative disordersPrincipal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Gunma University
Gene therapy against Rett syndrome and functional analysis of MeCP2, using blood-brain barrier-penetrating AAV vectorsPrincipal Investigator
- Principal Investigator
  
  HIRAI HIROKAZU
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Gunma University
Development of gene therapy against neurodegenerative diseases using CRISPR/Cas9-based genome editingPrincipal Investigator
- Principal Investigator
  
  Hirai Hirokazu
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Gunma University
Elucidation of cellular and nuclear signals that regulate motor learningPrincipal Investigator
- Principal Investigator
  
  Hirai Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Gunma University
Action potential regulation at the node of Ranvier and perineuronal nets' regulation of GABAergic transmission in the deep cerebellar nuclei
- Principal Investigator
  
  Hirono Moritoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Doshisha University
間葉系幹細胞による脳内環境の維持および破綻からの回復メカニズムの解明Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Long-term oral administration of the NMDA receptor antagonist memantine extends life span in spinocerebellar ataxia type 1 knock-in mice.
- Principal Investigator
  
  IIZUKA Akira
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gunma University
Functional roles of glial ATP receptors in neuron-glia interaction
- Principal Investigator
  
  HOSOI Nobutake
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Gunma University
Comprehensive Brain Science Network
- Principal Investigator
  
  Kimura Minoru
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Center for Novel Science Initatives, National Institutes of Natural Sciences
デルタ2グルタミン酸受容体のNTDを介する新しい活性化様式の解明Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Establishment and application of lentivector-based production of gene-rescue mouse for exploring gene functionsPrincipal Investigator
- Principal Investigator
  
  HIRAI Hirokazu
- Project Period (FY)
  2007 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (S)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Gunma University
デルタ2グルタミン酸受容体の細胞内信号伝達経路の解明Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
Genetic analyses of motor ataxia mutant mice
- Principal Investigator
  
  MASUYA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Institute of Physical and Chemical Research
小脳プルキンエ細胞特異的薬剤誘導性ポリグルタミン産生マウスの作出と解析Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gunma University
  Kanazawa University
脊髄小脳変性症の早期画像診断のための疾患モデルマウス作出および解析
- Principal Investigator
  
  藤井正彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Kobe University
Project to prove a link between phosphorylation of one amino-acid in glutamate receptors and motor learningPrincipal Investigator
- Principal Investigator
  
  HIRAI Hirokazu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Gunma University
  Kanazawa University
グリア細胞のAMPA型グルタミン酸受容体の活性化を介するシナプス機能の調節
- Principal Investigator
  
  小澤瀞司 (小沢瀞司)
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
^<31>P-NMRを用いたグルタミン酸受容体リン酸化の解明とその生理学的意義Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
記憶の維持に関与するプロテアーゼの研究
- Principal Investigator
  
  遠藤昌吾
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research
核磁気共鳴装置を用いたAMPA型グルタミン酸受容体リン酸化の分子生物学的研究Principal Investigator
- Principal Investigator
  
  平井宏和
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

[Book] ブレインサイエンスレビュー2007
- Author(s)
  平井宏和
- Publisher
  クバプロ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Book] 脳・神経科学集中マスター2005
- Author(s)
  平井宏和, 狩野方伸
- Publisher
  羊土社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Improving cell-specific recombination using AAV vectors in the murine CNS by capsid and expression cassette optimization2024
- Author(s)
  Kawabata Hayato、Konno Ayumu、Matsuzaki Yasunori、Sato Yumika、Kawachi Mika、Aoki Ryo、Tsutsumi Saki、Togai Shota、Kobayashi Ryosuke、Horii Takuro、Hatada Izuho、Hirai Hirokazu
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 32 Issue: 1 Pages: 101185-101185
- DOI
  10.1016/j.omtm.2024.101185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06454, KAKENHI-PROJECT-23K27482
[Journal Article] GABAergic neuron-specific whole-brain transduction by AAV-PHP.B incorporated with a new GAD65 promoter2021
- Author(s)
  Hoshino Chiaki、Konno Ayumu、Hosoi Nobutake、Kaneko Ryosuke、Mukai Ryo、Nakai Junichi、Hirai Hirokazu
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 1-18
- DOI
  10.1186/s13041-021-00746-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07103, KAKENHI-PROJECT-20K06906, KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19K06899, KAKENHI-PUBLICLY-19H04895, KAKENHI-PROJECT-20H02932, KAKENHI-PROJECT-16H06276
[Journal Article] BATTLE: Genetically Engineered Strategies for Split-Tunable Allocation of Multiple Transgenes in the Nervous System2020
- Author(s)
  Kohara Keigo、Inoue Akitoshi、Nakano Yousuke、Hirai Hirokazu、Kobayashi Takuya、Maruyama Masato、Baba Ryosuke、Kawashima Chiho
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101248-101248
- DOI
  10.1016/j.isci.2020.101248
- NAID
  120006884902
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19K22583, KAKENHI-PROJECT-19H03534
[Journal Article] Efficient whole brain transduction by systemic infusion of minimally purified AAV-PHP.eB2020
- Author(s)
  Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: 346 Pages: 108914-108914
- DOI
  10.1016/j.jneumeth.2020.108914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19K06899
[Journal Article] Protocol for BATTLE-1EX: A High-Resolution Imaging Method to Visualize Whole Synaptic Structures and their Components in the Nervous System2020
- Author(s)
  Inoue Akitoshi、Kobayashi Takuya、Hirai Hirokazu、Kanaya Noriko、Kohara Keigo
- Journal Title
  
  STAR Protocols
  
  Volume: 1 Issue: 3 Pages: 100166-100166
- DOI
  10.1016/j.xpro.2020.100166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19K22583, KAKENHI-PROJECT-19H03534
[Journal Article] Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance2020
- Author(s)
  Oe Yuki、Wang Xiaowen、Patriarchi Tommaso、Konno Ayumu、Ozawa Katsuya、Yahagi Kazuko、Hirai Hirokazu、Tian Lin、McHugh Thomas J.、Hirase Hajime
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 471-471
- DOI
  10.1038/s41467-020-14378-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06899, KAKENHI-PUBLICLY-18H05150, KAKENHI-PUBLICLY-19H05233, KAKENHI-PROJECT-16H01888, KAKENHI-PROJECT-18H02521
[Journal Article] Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia2020
- Author(s)
  Yasui Hiroyuki、Matsuzaki Yasunori、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Neuroscience
  
  Volume: - Pages: 328-336
- DOI
  10.1016/j.neuroscience.2020.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19K06899
[Journal Article] Ataxic phenotype and neurodegeneration are triggered by the impairment of chaperone‐mediated autophagy in cerebellar neurons2020
- Author(s)
  Sato Masahiro、Ohta Tomoko、Morikawa Yuri、Konno Ayumu、Hirai Hirokazu、Kurauchi Yuki、Hisatsune Akinori、Katsuki Hiroshi、Seki Takahiro
- Journal Title
  
  Neuropathology and Applied Neurobiology
  
  Volume: 47 Issue: 2 Pages: 198-209
- DOI
  10.1111/nan.12649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07101, KAKENHI-PROJECT-19K07123, KAKENHI-PROJECT-19K22813, KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-20H04126, KAKENHI-PROJECT-19K06899
[Journal Article] Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism2020
- Author(s)
  Chao Owen Y.、Marron Fernandez de Velasco Ezequiel、Pathak Salil Saurav、Maitra Swati、Zhang Hao、Duvick Lisa、Wickman Kevin、Orr Harry T.、Hirai Hirokazu、Yang Yi-Mei
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: - Issue: 7 Pages: 1159-1170
- DOI
  10.1038/s41386-020-0656-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02521
[Journal Article] ウイルスベクターの静脈投与によるマウス脳全域への遺伝子導入2019
- Author(s)
  今野歩, 平井宏和
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 581-587
- Data Source
  KAKENHI-PROJECT-18H02521
[Journal Article] ウイルスベクター経静脈投与による脊髄小脳変性症動物モデルの作出2019
- Author(s)
  平井宏和
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 37 Pages: 998-1002
- Data Source
  KAKENHI-PROJECT-18H02521
[Journal Article] Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice2019
- Author(s)
  Matsuzaki Yasunori、Tanaka Masami、Hakoda Sachiko、Masuda Tatsuki、Miyata Ryota、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Molecular Therapy
  
  Volume: 27 Issue: 4 Pages: 700-704
- DOI
  10.1016/j.ymthe.2019.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-18H02521
[Journal Article] Advanced CUBIC tissue clearing for whole-organ cell profiling2019
- Author(s)
  Matsumoto Katsuhiko、Mitani Tomoki T.、Horiguchi Shuhei A.、Kaneshiro Junichi、Murakami Tatsuya C.、Mano Tomoyuki、Fujishima Hiroshi、Konno Ayumu、Watanabe Tomonobu M.、Hirai Hirokazu、Ueda Hiroki R.
- Journal Title
  
  Nature Protocols
  
  Volume: 14 Issue: 12 Pages: 3506-3537
- DOI
  10.1038/s41596-019-0240-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06899, KAKENHI-PLANNED-18H05409, KAKENHI-PROJECT-18H02521, KAKENHI-PROJECT-19J13071
[Journal Article] Elavl3 is essential for the maintenance of Purkinje neuron axons2018
- Author(s)
  Ogawa Yuki、Kakumoto Kyoko、Yoshida Tetsu、Kuwako Ken-ichiro、Miyazaki Taisuke、Yamaguchi Junji、Konno Ayumu、Hata Junichi、Uchiyama Yasuo、Hirai Hirokazu、Watanabe Masahiko、Darnell Robert B.、Okano Hideyuki、Okano Hirotaka James
- Journal Title
  
  Sci Rep.
  
  Volume: 8 Issue: 1 Pages: 2722-2722
- DOI
  10.1038/s41598-018-21130-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08485, KAKENHI-PROJECT-17K09766, KAKENHI-PROJECT-16J11920, KAKENHI-PROJECT-15K06807, KAKENHI-PROJECT-16K14581, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Effects of Neutralizing Antibody Production on AAV-PHP.B-Mediated Transduction of the Mouse Central Nervous System2018
- Author(s)
  Shinohara Yoichiro、Konno Ayumu、Nitta Keisuke、Matsuzaki Yasunori、Yasui Hiroyuki、Suwa Junya、Hiromura Keiju、Hirai Hirokazu
- Journal Title
  
  Molecular Neurobiology
  
  Volume: - Issue: 6 Pages: 4203-4214
- DOI
  10.1007/s12035-018-1366-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-18H02521
[Journal Article] Intravenous administration of the adeno-associated virus-PHP.B capsid fails to upregulate transduction efficiency in the marmoset brain2018
- Author(s)
  Matsuzaki Yasunori、Konno Ayumu、Mochizuki Ryuta、Shinohara Yoichiro、Nitta Keisuke、Okada Yukihiro、Hirai Hirokazu
- Journal Title
  
  Neuroscience Letters
  
  Volume: 665 Pages: 182-188
- DOI
  10.1016/j.neulet.2017.11.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Regulatory connection between the expression level of classical protein kinase C and pruning of climbing fibers from cerebellar Purkinje cells2017
- Author(s)
  Takahashi Nobutaka、Shuvaev Anton N.、Konno Ayumu、Matsuzaki Yasunori、Watanave Masashi、Hirai Hirokazu
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 143 Issue: 6 Pages: 660-670
- DOI
  10.1111/jnc.14239
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Viral Vector-Based Evaluation of Regulatory Regions in the Neuron-Specific Enolase (NSE) Promoter in Mouse Cerebellum In Vivo2017
- Author(s)
  Shinohara Yoichiro、Ohtani Toshinori、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  The Cerebellum
  
  Volume: 16 Issue: 5-6 Pages: 913-922
- DOI
  10.1007/s12311-017-0866-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Minimal Purkinje Cell-Specific PCP2/L7 Promoter Virally Available for Rodents and Non-human Primates2017
- Author(s)
  Nitta Keisuke、Matsuzaki Yasunori、Konno Ayumu、Hirai Hirokazu
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 6 Pages: 159-170
- DOI
  10.1016/j.omtm.2017.07.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14929, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.2017
- Author(s)
  Goncalves N, Simoes AT, Prediger RD, Hirai H, Cunha RA, Pereira de Almeida L
- Journal Title
  
  Ann Neurol
  
  Volume: 81 Issue: 3 Pages: 407-418
- DOI
  10.1002/ana.24867
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] CD38 positively regulates postnatal development of astrocytes cell-autonomously and oligodendrocytes non-cell-autonomously.2017
- Author(s)
  Hattori T, Kaji M, Ishii H, Jureepon R, Takarada-Iemata M, Ta HM, Le TM, Konno A, Hirai H, Shiraishi Y, Ozaki N, Yamamoto Y, Okamoto H, Yokoyama S, Higashida H, Kitao Y, Hori O.
- Journal Title
  
  Glia
  
  Volume: 印刷中 Issue: 6 Pages: 974-989
- DOI
  10.1002/glia.23139
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01374, KAKENHI-PROJECT-26430069, KAKENHI-PROJECT-15K18374, KAKENHI-PROJECT-15K06753, KAKENHI-PROJECT-15H04254
[Journal Article] Protein Kinase C in the Cerebellum: Its Significance and Remaining Conundrums.2017
- Author(s)
  Hirai H.
- Journal Title
  
  Cerebellum
  
  Volume: 17 Issue: 1 Pages: 23-27
- DOI
  10.1007/s12311-017-0898-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] Progressive impairment of cerebellar mGluR signalling and its therapeutic potential for cerebellar ataxia in spinocerebellar ataxia type 1 model mice.2017
- Author(s)
  Shuvaev AN, Hosoi N, Sato Y, Yanagihara D, Hirai H.
- Journal Title
  
  The Journal of Physiology
  
  Volume: 595(1) Issue: 1 Pages: 141-164
- DOI
  10.1113/jp272950
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430003, KAKENHI-PROJECT-26750238, KAKENHI-PROJECT-15K01498, KAKENHI-PROJECT-15H04254
[Journal Article] Red fluorescent protein-based cAMP indicator applicable to optogenetics and in vivo imaging2017
- Author(s)
  Harada Kazuki、Ito Motoki、Wang Xiaowen、Tanaka Mika、Wongso Devina、Konno Ayumu、Hirai Hirokazu、Hirase Hajime、Tsuboi Takashi、Kitaguchi Tetsuya
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 7351-7351
- DOI
  10.1038/s41598-017-07820-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01922, KAKENHI-PROJECT-15H04254, KAKENHI-PROJECT-16J06838, KAKENHI-PROJECT-26460289, KAKENHI-PROJECT-16K15477, KAKENHI-PROJECT-15K18330
[Journal Article] FMRP Expression Levels in Mouse CNS Neurons Determine Behavioral Phenotype.2016
- Author(s)
  Arsenault J, Gholizadeh S, Niibori Y, Pacey LK, Halder SK, Koxhioni E, Konno A, Hirai H, Hampson DR
- Journal Title
  
  Human Gene Therapy
  
  Volume: 27 Issue: 12 Pages: 982-996
- DOI
  10.1089/hum.2016.090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18330, KAKENHI-PROJECT-15H04254
[Journal Article] Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα.2016
- Author(s)
  Iizuka A, Matsuzaki Y, Konno A, Hirai H.
- Journal Title
  
  Brain Structure and Function
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] Morphological and Functional Attenuation of Degeneration of Peripheral Neurons by Mesenchymal Stem Cell-Conditioned Medium in Spinocerebellar Ataxia Type 1-Knock-in Mice.2016
- Author(s)
  Suto N, Mieda T, Iizuka A, Nakamura K, Hirai H.
- Journal Title
  
  CNS Neurosci Ther
  
  Volume: 22 Issue: 8 Pages: 670-676
- DOI
  10.1111/cns.12560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] Mesenchymal stem cells attenuate peripheral neuronal degeneration in spinocerebellar ataxia type 1 knockin mice.2016
- Author(s)
  Mieda T, Suto N, Iizuka A, Matsuura S, Iizuka H, Takagishi K, Nakamura K, Hirai H.
- Journal Title
  
  J Neurosci Res
  
  Volume: 94 Issue: 3 Pages: 246-252
- DOI
  10.1002/jnr.23698
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-26111701
[Journal Article] Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43.2016
- Author(s)
  Nonaka T, Suzuki G, Tanaka Y, Kametani F, Hirai S, Okado H, Miyashita T, Saitoe M, Akiyama H, Masai H, Hasegawa M.
- Journal Title
  
  The journal of Biological Chemistry
  
  Volume: 291 Issue: 11 Pages: 5473-83
- DOI
  10.1074/jbc.m115.695379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18370, KAKENHI-PROJECT-221S0003, KAKENHI-ORGANIZER-25115001, KAKENHI-PLANNED-25115006, KAKENHI-PROJECT-23228004, KAKENHI-PROJECT-25250010, KAKENHI-PROJECT-14J03307, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26251004, KAKENHI-PROJECT-26290016, KAKENHI-PROJECT-16K14569, KAKENHI-PROJECT-16K14675
[Journal Article] Morphological and functional attenuation of degeneration of peripheral neurons by mesenchymal stem cell-conditioned medium in spinocerebellar ataxia type 1-knock-in mice2016
- Author(s)
  Suto N, Mieda T, Iizuka A, Nakamura K, Hirai H.
- Journal Title
  
  CNS Neuroscience & Therapeutics
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26111701
[Journal Article] Mesenchymal Stem Cells as a Potential Therapeutic Tool for Spinocerebellar Ataxia.2015
- Author(s)
  Nakamura K, Mieda T, Suto N, Matsuura S, Hirai H.
- Journal Title
  
  Cerebellum
  
  Volume: 14 Issue: 2 Pages: 165-170
- DOI
  10.1007/s12311-014-0604-1
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-26111701
[Journal Article] Dietary intake of sulforaphane-rich broccoli sprout extracts during juvenile and adolescence can prevent phencyclidine-induced cognitive deficits at adulthood.2015
- Author(s)
  Shirai Y, Fujita Y, Hashimoto R, Ohi K, Yamamori H, Yasuda Y, Ishima T, Suganuma H, Ushida Y, Takeda M, Hashimoto K.
- Journal Title
  
  PLoS One
  
  Volume: 24 Issue: 6 Pages: e0127244-e0127244
- DOI
  10.1371/journal.pone.0127244
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09865, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-25293250
[Journal Article] CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice2015
- Author(s)
  Yusuke Onaka, Norihito Shintani, Takanobu Nakazawa, Ryota Haba, Yukio Ago, Hyper Wang, Takuya Kanoh, Atsuko Hayata-Takano, Hiroyuki Hirai, Kin-ya Nagata, Masataka Nakamura, Ryota Hashimoto, Toshio Matsuda, James A. Waschek, Atsushi Kasai, Kazuki Nagayasu, Akemichi Baba, Hitoshi Hashimoto
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 284 Pages: 131-137
- DOI
  10.1016/j.bbr.2015.02.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J06144, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25460100, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-26293020, KAKENHI-PROJECT-26670122, KAKENHI-PROJECT-26670541, KAKENHI-PROJECT-26860055, KAKENHI-PUBLICLY-15H01288, KAKENHI-PROJECT-221S0003
[Journal Article] Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.2015
- Author(s)
  Duarte-Neves J, Goncalves N, Cunha-Santos J, Simoes AT, den Dunnen WF, Hirai H, Kugler S, Cavadas C, Pereira de Almeida L.
- Journal Title
  
  Hum Mol Genet
  
  Volume: 24 Issue: 19 Pages: 5451-5463
- DOI
  10.1093/hmg/ddv271
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.2015
- Author(s)
  Nobrega C, Carmo-Silva S, Albuquerque D, Vasconcelos-Ferreira A, Vijayakumar UG, Mendonca L, Hirai H, Pereira de Almeida L.
- Journal Title
  
  Brain
  
  Volume: 138 Issue: 12 Pages: 3537-3554
- DOI
  10.1093/brain/awv298
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Journal Article] A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance.2015
- Author(s)
  Ageta-Ishihara N, Yamazaki M, Konno K, Nakayama H, Abe M, Hashimoto K, Nishioka T, Kaibuchi K, Hattori S, Miyakawa T, Tanaka K, Huda F, Hirai H, Hashimoto K, Watanabe M, Sakimura K, Kinoshita M.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 10090-10090
- DOI
  10.1038/ncomms10090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-15K18342, KAKENHI-PUBLICLY-15H01297, KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-25117006, KAKENHI-PROJECT-24240048, KAKENHI-PROJECT-15H04274, KAKENHI-PROJECT-26640007, KAKENHI-PROJECT-26290021, KAKENHI-PROJECT-26440095, KAKENHI-PROJECT-25242078, KAKENHI-PUBLICLY-15H01429
[Journal Article] Long-term oral administration of the NMDA receptor antagonist memantine extends life span in spinocerebellar ataxia type 1 knock-in mice.2015
- Author(s)
  Akira Iizuka, Kazuhiro Nakamura, Hirokazu Hirai
- Journal Title
  
  Neuroscience letters
  
  Volume: 592 Pages: 37-41
- DOI
  10.1016/j.neulet.2015.02.055
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25830046
[Journal Article] Novel splice variants in the 5’UTR of Gtf2i expressed in the rat brain: alternative 5’UTRs and differential expression in the neuronal dendrites.2015
- Author(s)
  Yoshinori Shirai, Masahiko Watanabe, Hiroyuki Sakagami and Tatsuo Suzuki
- Journal Title
  
  J. Neurochemistry
  
  Volume: 134 Issue: 3 Pages: 578-589
- DOI
  10.1111/jnc.13136
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K06771, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-15H04672
[Journal Article] Retrograde semaphorin signaling regulates synapse elimination in the developing mouse brain2014
- Author(s)
  Uesaka N, Uchigashima,M, Mikuni T, Nakazawa T, Nakao H, Hirai K, Aiba A, Watanabe M, Kano M
- Journal Title
  
  Science
  
  Volume: 344 Issue: 6187 Pages: 1020-1023
- DOI
  10.1126/science.1252514
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24220007, KAKENHI-PROJECT-25000015, KAKENHI-PLANNED-25115010, KAKENHI-PROJECT-25640033, KAKENHI-PROJECT-25830004, KAKENHI-PROJECT-25830031
[Journal Article] Central CRTH2, a second prostaglandin D2 receptor, mediates emotional impairment in the lipopolysaccharide and tumor-induced sickness behavior model.2014
- Author(s)
  Haba R, Shintani N, Onaka Y, Kanoh T, Wang H, Takenaga R, Hayata A, Hirai H, Nagata KY, Nakamura M, Kasai A, Haghi moto R, Nagayasu K, Nakazawa T, Hashimoto H, Baba A.
- Journal Title
  
  J Neurosci.
  
  Volume: 34 Issue: 7 Pages: 2514-2523
- DOI
  10.1523/jneurosci.1407-13.2014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J02192, KAKENHI-PLANNED-21115006, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-23790086, KAKENHI-PROJECT-25293250, KAKENHI-PROJECT-25640033
[Journal Article] Distinct pathways leading to TDP-43-induced cellular dysfunctions.2014
- Author(s)
  Yamashita M, Nonaka T, Hirai S, Miwa A, Okado H, Arai T, Hosokawa M, Akiyama H, Hasegawa M.
- Journal Title
  
  Hum Mol Genet.
  
  Volume: 23 Issue: 16 Pages: 4345-56
- DOI
  10.1093/hmg/ddu152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24500429, KAKENHI-PROJECT-24591738, KAKENHI-PROJECT-24700370, KAKENHI-PUBLICLY-25123726, KAKENHI-PUBLICLY-26111730, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-26461733
[Journal Article] RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex.2013
- Author(s)
  Ohtaka-Maruyama C, Hirai S, Miwa A, Heng JI, Shitara H, Ishii R, Taya C, Kawano H, Kasai M, Nakajima K, Okado H.
- Journal Title
  
  Cell Rep
  
  Volume: 3(2) Issue: 2 Pages: 458-71
- DOI
  10.1016/j.celrep.2013.01.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-22240041, KAKENHI-PROJECT-22500318, KAKENHI-PROJECT-23500422, KAKENHI-PROJECT-23570264, KAKENHI-PLANNED-22111004
[Journal Article] Mesenchymal Stem Cells Ameliorate Cerebellar Pathology in a Mouse Model of Spinocerebellar Ataxia Type 1.2013
- Author(s)
  Matsuura S, Shuvaev AN, Iizuka A, Nakamura K, Hirai H.
- Journal Title
  
  Cerebellum
  
  Volume: epub Issue: 3 Pages: 323-330
- DOI
  10.1007/s12311-013-0536-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25830046, KAKENHI-PUBLICLY-26111701
[Journal Article] Methamphetamine increases locomotion and dopamine transporter activity in dopamine D52013
- Author(s)
  Hayashizaki S, Hirai S, Ito Y, Honda Y, Arime Y, Sora I, Okado H , Kodama T, Takada M.
- Journal Title
  
  PLoS ONE
  
  Volume: 8(10) Issue: 10 Pages: 1-8
- DOI
  10.1371/journal.pone.0075975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-24650192, KAKENHI-PUBLICLY-25110716, KAKENHI-PUBLICLY-25123726, KAKENHI-PROJECT-25250003, KAKENHI-PROJECT-25640011
[Journal Article] RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex2012
- Author(s)
  Hirai, S.,Miwa, A., Ohtaka-Maruyama, C., Kasa,i M., Okabe, S., Hata, Y, and H. Okado
- Journal Title
  
  EMBO Journal
  
  Volume: 31 Issue: 5 Pages: 1190-1202
- DOI
  10.1038/emboj.2011.486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220008, KAKENHI-PROJECT-221S0003, KAKENHI-PROJECT-22500318, KAKENHI-PROJECT-22590267, KAKENHI-PROJECT-22650070, KAKENHI-PUBLICLY-23123523, KAKENHI-PROJECT-23570264
[Journal Article] High Transgene expression by lentiviral vectors causes maldevelopment of Purkinje cells in vivo2010
- Author(s)
  Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev AN, Koyama C, Hirai H
- Journal Title
  
  Cerebellum (in press)
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] High transgene expression by lentiviral vectors causes maldevelopment of Purkinje cells in vivo2010
- Author(s)
  Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev A, Koyama C, Hirai H
- Journal Title
  
  The Cerebellum (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20021004
[Journal Article] High Transgene Expression by Lentiviral Vectors Causes Maldevelopment of Purkinje Cells In Vivo.2010
- Author(s)
  Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev AN, Koyama C, Hirai H.
- Journal Title
  
  The Cerebellum
  
  Volume: 9 Pages: 291-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] High transgene expression by lentiviral vectors causes maldevelopment of Purkinje cells in vivo.2010
- Author(s)
  Sawada Y, Kajiwara G, Iizuka A, Takayama K, Shuvaev A, Koyama C, Hirai H
- Journal Title
  
  The Cerebellum (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] The Ptdlns (3,4) P (2) phosphatase INPP4A is a suppressor of excitotoxic neuronal death.2010
- Author(s)
  Sasaki J, Kofuji S, Itoh R, Momiyama T, Takavama K, Murakami H, Chida S, Tsuya Y, Takasuga Eguchi S, Asanuma K, Horie Y, Miura K, Davies EM, Mitchell C, Yamazaki M, Hirai H, Takenaa T, Suzuki A, Sasaki T.
- Journal Title
  
  Nature
  
  Volume: 465 Pages: 497-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor.2009
- Author(s)
  Torashima T, Iizuka A, Horiuchi H, Mitsumura K, Yamasaki M, Koyama C, Takayama K, Iino M, Watanabe M, Hirai H
- Journal Title
  
  European Journal of Neuroscience 30
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] ウイルスベクターを用いた成熟マウス小脳皮質への遺伝子導入法2009
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 27
  
  Pages: 499-506
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] ウイルスベクターを用いた成熟マウス小脳皮質への遺伝子導入法2009
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 27
  
  Pages: 499-506
- Data Source
  KAKENHI-PROJECT-20021004
[Journal Article] Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor2009
- Author(s)
  Iizuka A, Takayama K, Torashima T, Yamasaki M, Koyama C, Mitsumura K, Watanabe M, Hirai H.akayama K, Torashima T, Horiuchi H, Hirai H
- Journal Title
  
  Neurobiology of Disease 35
  
  Pages: 457-465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20021004
[Journal Article] Characterization of mutant mice that express polyglutamine in cerebellar Purkinje cells.2009
- Author(s)
  One M, Mitsumura K, Toreshima T, Koyama C, Yamaguchi H, Furuya N, Hirai H
- Journal Title
  
  Brain Research 1255
  
  Pages: 9-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor.2009
- Author(s)
  Iizuka A, Takayama K, Torashima T, Yamasaki M, Koyama C, Mitsumura K, Watanabe M, Hirai H., akayama K, Torashima T, Horiuchi H, Hirai H
- Journal Title
  
  Neurobiology of Disease 35
  
  Pages: 457-465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Rescue of abnormal phenotypes in delta2 glutamate receptor-deficient mice by the extracellular N-terminal and intracellular C-terminal domains of the delta2 glutamate receptor2009
- Author(s)
  Torashima T, Iizuka A, Horiuchi H, Mitsumura K, Yamasaki M, Koyama C, Takayama K, Iino M, Watanabe M, Hirai H
- Journal Title
  
  European Journal of Neuroscience 30
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20021004
[Journal Article] Lentiviral-vector-mediated rescue of motor behavior in spontaneously occurring hereditary ataxic mice2009
- Author(s)
  Iizuka A, Takayama K, Torashima T, Yamasaki M, Koyama C, Mitsumura K, Watanabe M, Hirai H
- Journal Title
  
  Neurobiol Disease 35 (3)
  
  Pages: 457-65
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia2008
- Author(s)
  Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H
- Journal Title
  
  EMBO Reports
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Purkinje-ce11-preferential tranduction by lentiviral vectors with the murine stem cell virus promoter.2008
- Author(s)
  Takayama K, Tofashima T, Horiuchi H, Hirai H
- Journal Title
  
  Neuroscience Letters 443
  
  Pages: 7-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia2008
- Author(s)
  Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H
- Journal Title
  
  EMBO Rep 9 (4)
  
  Pages: 393-9
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Progress in transduction of cerebellar Purkinje, cells in vivo using viral vectors.2008
- Author(s)
  Hirai H
- Journal Title
  
  Cerebellum 7
  
  Pages: 273-278
- NAID
  120000807297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia2008
- Author(s)
  Torashima T, Koyama C, Iizuka A, Mitsumura K, Takayama K, Yanagi S, Oue M, Yamaguchi H, Hirai H
- Journal Title
  
  EMBO Reports (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18021014
[Journal Article] Inhibitory effects of the entiepileptic drug ethostiximide on G protein-activated inwardly rectifying K+channels.2008
- Author(s)
  Kobayashi T, Hirai H, Iino M, Fuse I, Mitstimura K, Washiyama K, Kasai S, Ikeda K
- Journal Title
  
  Neurepharmacology 56
  
  Pages: 499-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] Purkinje-cell-preferential transduction by lentiviral vectors with the murine stem cell virus promoter.2008
- Author(s)
  Takayama K, Torashima T , Horiuchi H, Hirai H
- Journal Title
  
  Neuroscience Letters 443
  
  Pages: 7-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20021004
[Journal Article] Potential usefulness of D2R reporter gene imaging by IBF as gene therapy monitoring for cerebellar neurodegene rative diseases.2008
- Author(s)
  Shiba K, Torashima T, Hirai H, Ogawa K, Akhter N , Makajima K, Kinuya S, Mori H
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism 29
  
  Pages: 434-440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19670003
[Journal Article] CD3 and IgG Fc receptor regulate cerebellar functions2007
- Author(s)
  Nakamura K, Hirai H, Tora shima T, Miyazaki T, Tsurui H, Xiu Y, Ohtsuji M, Lin QS, Tsukamoto K, Nishimura H, Ono M, Watanabe M, Hirose S
- Journal Title
  
  Molecular and Cellular Biology 27
  
  Pages: 5128-5134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18021014
[Journal Article] Production of neuron-preferential lentiviral vectors.2007
- Author(s)
  Torashima T, Koyama C, Higashida H, Hirai H.
- Journal Title
  
  Cerebellum (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] New concepts regulating synaptic transmission and plasticity.2007
- Author(s)
  Hirai H, Kano M.
- Journal Title
  
  KUBA PRO. Brain Science Review
  
  Pages: 123-140
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors.2007
- Author(s)
  Hirai H.
- Journal Title
  
  Cerebellum (In press)
- NAID
  120000807297
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Production of neuron-preferential lentiviral vectors.2007
- Author(s)
  Torashima T, Koyama C, Higashida H, Hirai H
- Journal Title
  
  Mature Protocols
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors2007
- Author(s)
  Hirai H
- Journal Title
  
  Cerebellum 6
  
  Pages: 1-6
- NAID
  120000807297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18021014
[Journal Article] Exposure of lentiviral vectors to subneutral pH shifts the tropism from Purkinje cell to Bergmann glia.2007
- Author(s)
  Torashima T, Yamada N, Itoh M, Yamamoto A, Hirai H.
- Journal Title
  
  Nature Protocols
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Exposure of lentiviral vectors to subneutral pH shifts the tropism from Purkinje cell to Bergmann glia2006
- Author(s)
  Torashima T, Yamada N, Itoh M, Yamamoto A, Hirai H
- Journal Title
  
  European Journal of Neuroscience 24
  
  Pages: 371-380
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] 神経細胞選択的なHIV由来レンチウィルスベクターの作製法2006
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 24
  
  Pages: 2997-3001
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Elucidation of the cerebellar function by generating2006
- Author(s)
  Hirai H.
- Journal Title
  
  Experimental Medicine 24(No.15)
  
  Pages: 2402-2409
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] 神経細胞選択的なHIV由来レンチウィルスベクターの作製法2006
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 24
  
  Pages: 2997-3001
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors2006
- Author(s)
  Torashima T, Okoyama S, Nishizaki T, Hirai H.
- Journal Title
  
  Brain Research 1082
  
  Pages: 11-22
- NAID
  130007038943
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Molecular and cellular mechanisms regulating synaptogenesis and synaptic plasticity in the cerebellum.2006
- Author(s)
  Hirai H.
- Journal Title
  
  Experimental Medicine 24
  
  Pages: 2997-3001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] 小脳シナプス形成とシナプス可塑性を制御する分子・細胞メカニズム2006
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 24
  
  Pages: 2402-2409
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors2006
- Author(s)
  Torashima T, Okoyama S, Nishizaki T, Hirai H
- Journal Title
  
  Brain Research 1082
  
  Pages: 11-22
- NAID
  130007038943
- Data Source
  KAKENHI-PROJECT-17650106
[Journal Article] In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors.2006
- Author(s)
  Torashima T, Okoyama S, Nishizaki T, Hirai H.
- Journal Title
  
  European Journal of Neuroscience 24
  
  Pages: 371-380
- NAID
  130007038943
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Exposure of lentiviral vectors to subneutral pH shifts the tropism from Purkinje cell to Bergmann glia2006
- Author(s)
  Torashima T, Yamada N, Itoh M, Yamamoto A, Hirai H
- Journal Title
  
  European Journal of Neuroscience 24
  
  Pages: 371-380
- Data Source
  KAKENHI-PROJECT-17650106
[Journal Article] In vivo transduction of murine cerebellar Purkinje cells by HIV-derived lentiviral vectors2006
- Author(s)
  Torashima T, Okoyama S, Nishizaki T, Hirai H
- Journal Title
  
  Brain Research 1082
  
  Pages: 11-22
- NAID
  130007038943
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Phosphorylation of the glutamate receptor and motor learning.2006
- Author(s)
  Hirai H.
- Journal Title
  
  Brain Research 1082(1)
  
  Pages: 11-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] 小脳シナプス形成とシナプス可塑性を制御する分子・細胞メカニズム2006
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 24(No. 15)(増刊)
  
  Pages: 2402-2409
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Progress in transduction of cerebellar Purkinje cells in vivo using viral vectors.2005
- Author(s)
  Hirai H.
- Journal Title
  
  Experimental Medicine 23(8)
  
  Pages: 1170-1175
- NAID
  120000807297
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] 遺伝子レスキューマウス作出による小脳の運動学習機構の解明2005
- Author(s)
  平井宏和
- Journal Title
  
  実験医学 23(8)
  
  Pages: 1170-1175
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Production of HIV-derived lentiviral vectors with high tropism for neurons.2005
- Author(s)
  Hirai H.
- Journal Title
  
  YODOSHA brain-neuroscience intensive master
  
  Pages: 70-76
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Journal Article] Ca2+ permeability of the channel pore is not essential for the {delta}2 glutamate receptor to regulate synaptic plasticity and motor coordination.
- Author(s)
  Kakegawa W, Miyazaki T, Hirai H, Motohashi J, Mishima M, Watanabe M, Yuzaki M
- Journal Title
  
  Journal of Physiology (In press)
- Data Source
  KAKENHI-PROJECT-18021014
[Patent] 改良型ミクログリア標的ＡＡＶベクター2024
- Inventor(s)
  平井宏和, 今野　歩, 青木　遼
- Industrial Property Rights Holder
  平井宏和, 今野　歩, 青木　遼
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-013394
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23K27482
[Patent] 目的遺伝子を脳で小脳プルキンエ細胞、脳幹および嗅球特異的に過剰発現するトランスジェニック非ヒト哺乳動物2010
- Inventor(s)
  平井宏和
- Industrial Property Rights Holder
  群馬大学
- Industrial Property Number
  2010-129021
- Filing Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-19670003
[Patent] プルキンエ細胞指向性ウイルスベクター2007
- Inventor(s)
  平井宏和, 寅嶋崇
- Industrial Property Rights Holder
  金沢大学
- Filing Date
  2007-03-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Patent] プルキンエ細胞指向性ウイルスベクター2006
- Inventor(s)
  平井宏和, 寅嶋崇
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2006-198398
- Filing Date
  2006-07-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300100
[Presentation] Development of AAV vectors targeting various cell types in the brain2024
- Author(s)
  Hirokazu Hirai
- Organizer
  The 14th International Symposium of Gunma University Initiative for Advanced Research (GIAR)
- Data Source
  KAKENHI-PROJECT-23K27482
[Presentation] マウス及びマーモセットの脳内のさまざまな細胞種特異的AAVベクターの開発2024
- Author(s)
  平井宏和、深井悠貴、川畑勇人、青木遼、松崎泰教、今野歩
- Organizer
  第 101 回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-23K27482
[Presentation] 脳内のさまざまな細胞種標的AAVベクターの開発2024
- Author(s)
  平井宏和、今野歩、松崎泰教、堤咲樹、深井悠貴、青木遼
- Organizer
  第６回 JMU-CGTRシンポジウム 2024
- Invited
- Data Source
  KAKENHI-PROJECT-23K27482
[Presentation] アデノ随伴ウイルスベクターの静脈内投与による脳内細胞種特異的な遺伝子発現法の開発2023
- Author(s)
  平井宏和、川畑勇人、深井悠貴、松崎泰教、今野歩
- Organizer
  第29回日本遺伝子細胞治療学会学術集会
- Data Source
  KAKENHI-PROJECT-23K27482
[Presentation] Development of AAV vectors targeting a specific cell population - from mouse to marmoset2023
- Author(s)
  平井宏和
- Organizer
  第64回日本神経病理学会総会学術研究会/第66回日本神経化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-23K27482
[Presentation] Mouse strain-dependent BBB (blood-brain barrier) permeability of AAV-PHP.B.2019
- Author(s)
  Yasunori Matsuzaki, Masami Tanaka, Sachiko Hakoda, Tatsuki Masuda, Ryota Miyata, Ayumu Konno, Hirokazu Hirai
- Organizer
  FAOPS2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02521
[Presentation] 小脳プルキンエ細胞における古典的Cキナーゼαとγの発現量と生理機能2017
- Author(s)
  平井宏和
- Organizer
  第39回日本生物学的精神医学会・第47回日本神経精神薬理学会　合同年会
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] In vivo evaluation of efficacy of the shortened WPRE sequence in cerebellum2017
- Author(s)
  Ayumu Konno, Kazuma Hachisu, Rika terashima, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] AAV9 vector-mediated production of mouse model of spinocerebellar ataxia type 3 and electrophysiological analysis of the mouse2017
- Author(s)
  Chiaki Hoshino, Masashi Watanabe, Ayumu Konno, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Regulation of cerebellar function by protein kinase C2017
- Author(s)
  Hirokazu Hirai
- Organizer
  International Symposium of the Society for Research on the Cerebellum and Ataxias
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] AAV9 vector-mediated production of mouse model of spinocerebellar ataxia type 3 and electrophysiological analysis of that mouse2017
- Author(s)
  Chiaki Hoshino, Masashi Watanabe, Ayumu Konno, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] Pros and cons of an AAV double infection method combined with the Tet system :An experimental study2017
- Author(s)
  Nobutake Hosoi, Masayuki Shichida, Ayumu Konno, Hirokazu Hirai
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] In vivo evaluation of the shortened-WPRE in the cerebellum2017
- Author(s)
  Ayumu Konno, Kazuma Hachisu, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] Regulation of the firing property in mature Purkinje cells by PKC γ contributes to the motor coordination2017
- Author(s)
  Masashi Watanabe, Nobutaka Takahashi, Ayumu Konno, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] アデノ随伴ウイルスによる遺伝子導入を介したリピート病モデル動物の作出と治療法の開発2017
- Author(s)
  今野歩, 渡邊将, 星野千秋, 篠原洋一郎, 松﨑泰教, 平井宏和
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] Low concentration of a GABAb receptor agonist improves motor performance in spinocerebellar ataxia type 1 (SCA1) model mice2017
- Author(s)
  Nobutake Hosoi, Shuvaev N Anton, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Pros and cons of an AAV double infection method combined with the Tet system: An experimental study2017
- Author(s)
  Ayumu Konno, Hirokazu Hirai
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Low concentration of a GABAb receptor agonist improves motor performance in spinocerebellar ataxia type 1 (SCA1) model mice2017
- Author(s)
  Nobutake Hosoi, Shuvaev N Anton, Hirokazu Hirai
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] 脊髄小脳変性症1型モデルマウスにおける短期・長期シナプス可塑性とCa2+シグナルの進行性異常2016
- Author(s)
  細井延武、アントンシュワエフ、平井宏和
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Impaired synaptic plasticity at cerebellar parallel fiber-Purkinje cell synapses in AAV vector-based mouse model of spinocerebellar ataxia type 32016
- Author(s)
  Masashi Watanabe, Ayumu Konno, Hirokazu Hirai
- Organizer
  第３９回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K15477
[Presentation] 脊髄小脳変性症1型(SCA1)モデルマウスにおける短期・長期シナプス可塑性とCa2+シグナルの進行性異常2016
- Author(s)
  細井延武、 Anton Shuvaev、平井　宏和
- Organizer
  第39回　日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Progressive abnormalities in short-and long term synaptic plasticity and dendritic Ca2+ signals in spinocerebellar ataxia type 1 (SCA1) model mice.2016
- Author(s)
  細井延武、シュワエフアントン、平井宏和
- Organizer
  第９３回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (北海道札幌市)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Progressive impairment of metabotropic glutamate receptor(mGluR) mediated signaling and carebellar synaptic plasticity in spinocerebellar ataxia type 1(SCA1) model mice2016
- Author(s)
  Nobutake Hosoi, Anton N Shuvaev, Hirokazu Hirai
- Organizer
  Neuroscience 2016
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Probing expression pattern of a novel AAV double infection method combined with the Tet system and the glia specific GFAP promoter2016
- Author(s)
  Nobutake Hosoi, Masayuki Shichida, Ayumu Konno and Hirokazu Hirai
- Organizer
  10th FENS Forum of Neuroscience
- Place of Presentation
  コペンハーゲン　（デンマーク）
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Progressive impairment of metabotropic glutamate receptor (mGluR)-mediated signaling and cerebellar synaptic plasticity in spinocerebellar ataxia type 1 (SCA1) model mice2016
- Author(s)
  N. HOSOI, A. Shuvaev, H. Hirai
- Organizer
  Neuroscience 2016 SfN 46th Annual meeting
- Place of Presentation
  サンディエゴ　（アメリカ）
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Generation of a marmoset model of spinocerebellar ataxia type 3 via AAV9 vector-mediated gene transfer2016
- Author(s)
  Ayumu Konno, Yasunori Matsuzaki, Hirokazu Hirai
- Organizer
  Neuroscience 2016
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Inflammation-induced switch of the neuron-specific enolase promoter activity from Purkinje neuron to Bergmann glia.2016
- Author(s)
  Yusuke Sawada, Ayumu Konno, Toshinori Ohtani, Nobutaka Takahashi, Yasunori Matsuzaki, Shoji Kishi, Hirokazu Hirai.
- Organizer
  第６回国際放射線神経生物学会大会
- Place of Presentation
  長崎大学良順会館 (長崎県長崎市)
- Year and Date
  2016-02-12
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] 脊髄小脳変性症1型（SCA1)モデルマウスにおけるｍGluRを介したシナプス伝達の進行性異常2015
- Author(s)
  細井　延武、平井　宏和
- Organizer
  第5回国際放射線神経生物学会大会
- Place of Presentation
  高崎シティギャラリー　（群馬県高崎市）
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Mesenchymal stem cell-conditioned medium alleviates the peripheral pathology in spinocerebellar ataxia type 1-knockin mice.2015
- Author(s)
  Suto N, Nakamura K, Hirai H.
- Organizer
  第5回国際放射線神経生物学会大会
- Place of Presentation
  高崎
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] 短縮型マウスGFAPプロモーターとTet systemを組み合わせた新規AAV二重感染法による遺伝子発現のグリア特異性の検討2015
- Author(s)
  七田真之、細井延武、今野歩、平井宏和
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場、神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] Fusion of mesenchymal stem cells exclusively with degenerating cerebellar neurons in spinocerebellar ataxia model mice.2015
- Author(s)
  Hirokazu Hirai, Yiping Fan, Ayumu Konno, Yasunori Matsuzaki, Nobutake Takahashi, Chan K.Y.Jerry, Huda Fathul
- Organizer
  第３８回日本神経科学大会
- Place of Presentation
  神戸国際会議場 (兵庫県神戸市)
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] 短縮型マウスGFAPプロモーターとTet systemを組み合わせたAAV二重感染法による遺伝子発現のグリア特異性の検討2015
- Author(s)
  七田　真之、細井　延武、　今野　歩、　平井　宏和
- Organizer
  第5回国際放射線神経生物学会大会
- Place of Presentation
  高崎シティギャラリー　（群馬県高崎市）
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] 脊髄小脳変性症１型(SCA1)モデルマウスにおけるmGluRを介したシナプス伝達の進行性異常2015
- Author(s)
  細井延武、平井宏和
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場、神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] 脊髄小脳失調症１型の変異遺伝子をもつ間葉系幹細胞の治療効果の検討2015
- Author(s)
  澤田悠輔、今野歩、松﨑泰教、Fathul Huda、高橋伸卓、平井宏和
- Organizer
  第３８回日本神経科学大会
- Place of Presentation
  神戸国際会議場 (兵庫県神戸市)
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] Progressive impairment of cerebellar mGluR signaling in SCA1 model mice.2015
- Author(s)
  Nobutake Hosoi, Hirokazu Hirai.
- Organizer
  第３８回日本神経科学大会
- Place of Presentation
  神戸国際会議場 (兵庫県神戸市)
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Gene and stem cell therapies against polyglutamine diseases.2015
- Author(s)
  平井宏和
- Organizer
  第５６回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ (新潟県新潟市)
- Year and Date
  2015-05-20
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] Fusion of mesenchymal stem cells exclusively with “degenerating” cerebellar neurons in spinocerebellar ataxia type 1 model mice.2015
- Author(s)
  Huda F, Fan, Y, Konno A, Matsuzaki Y, Takahashi N, Chan JKY, Hirai H.
- Organizer
  第5回国際放射線神経生物学会大会
- Place of Presentation
  高崎
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] Gene and stem cell therapies against polyglutamine diseases.2015
- Author(s)
  平井宏和
- Organizer
  第５６回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ (新潟県新潟市)
- Year and Date
  2015-05-20
- Invited
- Data Source
  KAKENHI-PROJECT-15H04254
[Presentation] Exploring the original function of AMPA receptor2015
- Author(s)
  Shinobu Hirai, Koji Hotta, Yoshihiro Kubo, Yasushi Okamura, Haruo Okado
- Organizer
  第９２回日本生理学会（神戸）
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-221S0003
[Presentation] Intrathecal injection of mesenchymal stem cells ameliorates cerebellar pathology of spinocerebellar ataxia type 1 mice.2015
- Author(s)
  Matsuura S, Nakamura K, Hirai H.
- Organizer
  第5回国際放射線神経生物学会大会
- Place of Presentation
  高崎
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] けいれん重積モデルマウスにおける抑制性ニューロンの変化2014
- Author(s)
  中島啓介、平井清華、平井志伸、岡戸晴生
- Organizer
  第３７回日本神経科学大会（横浜）
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PROJECT-221S0003
[Presentation] 小脳性運動失調とシナプス伝達異常2014
- Author(s)
  細井延武、平井宏和
- Organizer
  第９１回　日本生理学会大会
- Place of Presentation
  鹿児島大学　郡元キャンパス　（鹿児島）
- Invited
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] レンチ宅イルスベクターを利用した神経細胞への遺伝子導入で何ができるのか?2011
- Author(s)
  平井宏和
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  横浜(中止により紙上発表のみ)
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] RP58 controls the ratio of neuron to astrocytes by down-regulating allId-family genes expression in the developing cortex2011
- Author(s)
  平井志伸
- Organizer
  第３４回日本神経科学大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-221S0003
[Presentation] レンチウイルスベクターを用いた小脳の発達・再生研究2010
- Author(s)
  平井宏和、澤田悠輔、梶原剛
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] A PKCγ mutation in spinocerebellar ataxia type 14 impairs PKC functions in a dominant-negative manner in cerebellar Purkinje cells in vivo2010
- Author(s)
  Anton Shuvaev, Tomohiko Irie, Hajime Horiuchi, Akira Iiduka, Masae lino, Takahiro Seki, Norio Sakai, Hirokazu Hirai
- Organizer
  第87回日本生理学会
- Place of Presentation
  盛岡
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia2009
- Author(s)
  平井宏和
- Organizer
  5th International Symposium on Genomic Medicine of CCH
- Place of Presentation
  Changhua Christian Hospital, Taichung, Taiwan
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Rescue of abnormal phenotypes in σ2 glutamate-receptor-null mice by the extracellular N-terminal domain.2009
- Author(s)
  Torashima T, 飯塚朗, 堀内始, 三ツ村一浩, Yamazaki M, 小山知穂, 高山清彦, 飯野昌枝, Watanabe M, 平井宏和
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Rescue of abnormal phenotypes in σ2 glutamate-receptor-null mice by the extracellular N-terminal domain2009
- Author(s)
  Torashima T, Iizuka A, Horiuchi H, Mitsumura K, Yamazaki M, Koyama C, Takayama K, Iino M, Watanabe M, Hirai H
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] 機能ドメインを土台としたδ2グルタミン酸受容体研究の進展2009
- Author(s)
  平井宏和, 寅嶋崇, 飯塚朗
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] Lentivector-mediated rescue from cerebellar ataxia in a mouse model of spinocerebellar ataxia2009
- Author(s)
  平井宏和
- Organizer
  5th International Symposium on Genomic Medicine of CCH
- Place of Presentation
  Changhua Christian Hospital, Taichung, Taiwan
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] Lentiviral vector-mediated rescue of cerebellar ataxia in a mouse model of spinocerebellar ataxia2009
- Author(s)
  平井宏和
- Organizer
  Annual Meeting of Chinese Medical Association
- Place of Presentation
  Taipei Veterans General Hospital, Taipei, Taiwan
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] 高力価レンチウイルスベクターの感染が小脳プルキンエ細胞の発達におよぼす影響の検討2009
- Author(s)
  澤田悠輔, 梶原剛, 寅嶋崇, 高山清彦, 堀内始, 飯塚朗, 三ツ村一浩, 平井宏和
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] A PKCγ mutations in spinocerebellar ataxia type 14 impairs PKC functions in cerebellar Purkinje cells in vivo2009
- Author(s)
  Shuvaev NA, Sakai N, Seki T, Iino M, Horiuchi H, Hirai H.
- Organizer
  The 36th International Congress of Physiological Sciences
- Place of Presentation
  京都国際会議場 (Kyoto)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] 機能ドメインを土台としたδ2グルタミン酸受容体研究の進展2009
- Author(s)
  平井宏和, 寅嶋崇, 飯塚朗
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Lentiviral vector-mediated rescue of cerebellar ataxia in a mouse model of spinocerebellar ataxia2009
- Author(s)
  平井宏和
- Organizer
  Annual Meeting of Chinese Medical Association
- Place of Presentation
  Taipei Veterans General Hospital, Taipei, Taiwan
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] A PKC γ mutations in spinocerebellar ataxia type 14 impairs PKCfunctions in cerebellar Purkinje cells in vivo2009
- Author(s)
  Shuvaev NA, Hirai H, Sakai N, Seki T, Iino M, Horiuchi H
- Organizer
  第36回国際生理学会世界大会
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いた遺伝性運動失調マウスの機能回復2009
- Author(s)
  飯塚朗, 寅嶋崇, 三ツ村一浩, 小山知穂, 飯野昌枝, 平井宏和
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] 高力価レンチウイルスベクターの感染が小脳プルキンエ細胞の発達におよぼす影響の検討2009
- Author(s)
  澤田悠輔, 梶原剛, 寅嶋崇, 高山清彦, 堀内始, 飯塚朗, 三ツ村一浩, 平井宏和
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いた遺伝性運動失調マウスの機能回復2009
- Author(s)
  飯塚朗, 寅嶋崇, 三ツ村一浩, 小山知穂, 飯野昌枝, 平井宏和
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いたδ2グルタミン酸受容体欠損マウスのレスキュー2008
- Author(s)
  飯塚朗、三ツ村一浩、飯野昌枝、寅嶋崇、小山知穂、平井宏和
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] レンチウイルスベクターの進歩中枢神経系の病態生理解明と脳神経疾患の遺伝子治療への応用2008
- Author(s)
  平井宏和
- Organizer
  第31回日本神経科学大会(シンポジウム)
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] レγチウイルスベクターの進歩-中枢神経系の病態生理解明と脳神経疾患の遺伝子治療への応用-2008
- Author(s)
  平井宏和
- Organizer
  第31回日本神経科学大会(シンポジウム)
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Purkinje-cell-selective transduction by the MSCV promoter incorporated in lentiviral vectors2008
- Author(s)
  KIYOHIKO TAKAYAMA, TAKA SHI TORASHIMA, HAJIME HO RIUCHI, HIROKAZU HIRAI
- Organizer
  北米神経科学学会
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] レンチウイルスベクターの作製方法とその応用2008
- Author(s)
  平井宏和
- Organizer
  第33回組織細胞化学講習会
- Place of Presentation
  神戸
- Year and Date
  2008-08-06
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウィルスベクターを用いたプルキン午細胞選択的なGFP発現2008
- Author(s)
  高中清彦、寅嶋崇、堀内始、平井宏和
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Purkinje-cell-selective transduction by the MSCV promoter incorporated in lentiviral vectors2008
- Author(s)
  Takayama K, Torashima T, Horiuchi H, Hirai H.
- Organizer
  Neuroscience 2008
- Place of Presentation
  Convention Center, Washington DC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いた神経科学研究と遺伝子治療2008
- Author(s)
  平井宏和
- Organizer
  「生体調節シグナルの統合的研究」第3回合同シンポジウム
- Place of Presentation
  秋田
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] In vivo幼若ラット小脳皮質神経細胞へのレンチウイルスベクターを用いた遺伝子導入2008
- Author(s)
  梶原剛, 澤田悠輔, 寅嶋崇, 高山清彦, 堀内始, 飯塚朗, 三ツ村一浩, 飯野昌枝, 小山知穂, 平井宏和
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] Purkinje-cell-selective transduction by the MSCV promoter incorporated in lentiviral vectors2008
- Author(s)
  KIYOHIKO TAKAYAMA, TAKASHI TORASHIMA, HAJIME HORIUCHI, HIROKAZU HIRAI
- Organizer
  北米神経科学学会
- Place of Presentation
  Washington DC
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いたδ2グルタミン酸受容体欠損マウスのレスキュー-アミノ酸リガンド結合部位及びチャネルポアが欠損しても機能は障害されない-2008
- Author(s)
  飯塚朗, 三ツ村一浩, 小山知穂, 寅嶋崇, 飯野昌枝, 平井宏和
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いたCRAG発現による脊髄小脳変性症モデルマウスのシナプス伝達及び可塑性の回復2008
- Author(s)
  三ツ村一浩, 飯野昌枝, 飯塚朗, 寅嶋崇, 小山知穂, 高山清彦, 堀内始, 平井宏和
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19670003
[Presentation] レンチウイルスベクターを用いたδ2グルタミン酸受容体欠損マウスのレスキュー-アミノ酸リガンド結合部位及びチャネルポアが欠損しても機能は障害されない-2008
- Author(s)
  飯塚朗、三ツ村一浩、小山知穂、寅嶋崇、飯野昌枝、平井宏和
- Organizer
  第85回日本生理学会大会
- Place of Presentation
  東京
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18021014
[Presentation] レンチウイルスベクターを用いた神経科学研究と遺伝子治療2008
- Author(s)
  平井宏和
- Organizer
  「生体調節シグナルの統合的研究」第3回合同シンポジウム
- Place of Presentation
  秋田
- Year and Date
  2008-10-17
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] レンチウイルスベクターを用いたプルキンエ細胞選択的なGFP発現2008
- Author(s)
  高山清彦、寅嶋崇、堀内始・平井宏和
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20021004
[Presentation] デルタ2グルタミン酸受容体の細胞内信号伝達経路の解明2007
- Author(s)
  平井宏和
- Organizer
  文部科学省特定領域研究「統合脳」夏のワークショップ(シンポジウム)
- Place of Presentation
  札幌
- Year and Date
  2007-08-22
- Data Source
  KAKENHI-PROJECT-18021014
[Presentation] Molecular mechanisms and potential therapies of the spinocerebellar ataxia and the future perspective of the clinical application.
- Author(s)
  Hirokazu Hirai
- Organizer
  International Congress on Neuroscience
- Place of Presentation
  クラスノヤルスク、ロシア
- Year and Date
  2014-06-19 – 2014-06-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] Distinct transduction profiles resul ting from direct cortical,intrathecal or intravenous injection of AAV9 in the CNS.
- Author(s)
  Huda F, Konno A, Matsuzaki Y, Goenawan H, Miyake K, Shimada T, Hirai H.
- Organizer
  9th Federation of European Neuroscience Societies
- Place of Presentation
  ミラノ、イタリア
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] 間葉系幹細胞による脊髄小脳変性症１型モデルマウスの治療
- Author(s)
  中村　和裕、平井宏和
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] Cerebellar transduction profiles after ssAAV9 injection via cortical, intrathecal or intravenous routes.
- Author(s)
  Huda F, Konno A, Matsuzaki Y, Goenawan H, Miyake K, Shimada T, Hirai H.
- Organizer
  第37回日本神経科学学会大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] 脊髄小脳変性症1型（SCA1)モデルマウスにおけるｍGluRを介したシナプス伝達の進行性異常
- Author(s)
  細井　延武、平井　宏和
- Organizer
  生理学研究所　研究会　「シナプス・神経ネットワークの機能ダイナミクス」
- Place of Presentation
  生理学研究所（愛知県岡崎市）
- Year and Date
  2014-12-02 – 2014-12-03
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] 間葉系幹細胞由来神経栄養因子の脊髄小脳変性症に対する治療効果検討
- Author(s)
  須藤奈々、中村和裕、平井宏和
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] ABNORMALITIES OF METABOTROPIC GLUTAMATE RECEPTOR (MGLUR)-MEDIATED SIGNALING AT CEREBELLAR PARALLEL FIBER-PURKINJE CELL SYNAPSES IN SPINOCEREBELLAR ATAXIA TYPE 1 (SCA1) MODEL MICE
- Author(s)
  Nobutake Hosoi, Hirokazu Hirai
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  ミラノ (イタリア)
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-25430003
[Presentation] RP58 splicing variantの発現パターンと機能解析
- Author(s)
  平井清華、岡戸晴生
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-221S0003
[Presentation] OSVZ-like structure observed in RP58 deficient cortex
- Author(s)
  Okado H, Hirai S, Ohtaka-Maruyama C, Miwa A, Kasai M
- Organizer
  第35回日本神経科学学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-221S0003
[Presentation] 間葉系幹細胞の髄腔内投与による脊髄小脳変性症１型モデルマウスの神経変性改善
- Author(s)
  松浦瀬里奈、中村和裕、平井宏和
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PUBLICLY-26111701
[Presentation] NMDA受容体拮抗薬メマンチンの長期経口投与によるSCA1モデルマウス病態の改善
- Author(s)
  Akira Iizuka, Kazuhiro Nakamura, Hirokazu Hirai
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-25830046
[]

1. KONNO Ayumu (40509048)

# of Collaborated Projects: 5 results

# of Collaborated Products: 22 results
2. HOSOI Nobutake (90543570)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
3. YANAGIHARA Dai (90252725)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MATSUZAKI Yasunori (50738200)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. Yanagawa Yuchio (90202366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. IIZUKA Akira (10466683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. NAKAMURA Kazuhiro (10327835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. MASUYA Hiroshi (40321814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. WAKANA Shigeharu (90192434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Kimura Minoru (40118451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Tanji Jun (10001885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Takada Masahiko (00236233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Nakamura Katsuki (70243110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Ohtsuka Toshihisa (40401806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Aoki Shigeki (80222470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. Takao Hidemasa (10444093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Shimoji Keigo (20348931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Goto Masami (30375844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Yoshiura Takashi (40322747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Nakata Yasuhiro (40362066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Abe Osamu (50302716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. Masumoto Tomohiko (60302717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. Tokumaru Aya (60507391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. Matsumura Akira (90241819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Kirino Eiji (90276460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Terada Hitoshi (90277319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. Sato Noriko (10322017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. Kasai Kiyoto (80322056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
29. Hashimoto Ryota (10370983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. Niwa Shin-ichi (30110703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. Kato Tadafumi (30214381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. Suzuki Michio (40236013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
33. Shuji Iritani (60191904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
34. Nemoto Kiyotaka (80550152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. Tomita Hiroaki (90295064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
36. Murayama Shigeo (50183653)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
37. Akatsu Hiroyasu (00399734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Takao Masaki (50245487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. Saito Yuko (60344066)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
40. Bito Haruhiko (00291964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
41. Yoshimura Yumiko (10291907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
42. Matsuzaki Masanori (50353438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
43. Furuta Toshiaki (90231571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
44. Okado Haruo (60221842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
45. Saito Izumu (70158913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
46. Kaibuchi Kozo (00169377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
47. Hasegawa Masato (10251232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
48. Aiba Atsu (20271116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
49. Shiina Nobuyuki (30332175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
50. Igarashi Michihiro (50193173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
51. Tomoki Nishioka (70435105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
52. Watanabe Masahiko (70210945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
53. Koike Masato (80347210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
54. Sakagami Hiroyuki (90261528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
55. Shigemoto Ryuichi (20221294)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
56. Fukazawa Yugo (60343745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. Sakimura Kenji (40162325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
58. Mori Hisashi (00239617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. Mishina Masayoshi (80144351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. Kobayashi Kazuto (90211903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
61. Uemura Tadashi (80213396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. Ishihara Takeshi (10249948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. Nose Akinao (30260037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. Iino Yuichi (40192471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. Miyakawa Tsuyoshi (10301780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. Takao Keizo (80420397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
67. Mushiake Hajime (80219849)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
68. Katayama Norihiro (20282030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
69. Tanaka Tetsu (40417382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
70. Inoue Kazuhide (80124379)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
71. Okabe Shigeo (60204012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
72. Kano Masanobu (40185963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
73. Fujiyama Fumino (20244022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
74. Isa Tadashi (20212805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
75. Kageyama Ryoichiro (80224369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
76. Fujita Ichiro (60181351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
77. Yoshida Akira (70257187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
78. Nishikawa Toru (00198441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. Nukina Nobuyuki (10134595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
80. Fukai Tomoki (40218871)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
81. Iwatsubo Takeshi (50223409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. Yamamori Tetsuo (80260206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. Okazawa Hitoshi (50261996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. Tanaka Keiji (00221391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. Kakigi Ryusuke (10145196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. Tsuda Ichiro (10207384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. Kitazawa Shigeru (00251231)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
88. Doya Kenji (80188846)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. Takahashi Ryosuke (90216771)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. Ikenaka Kazuhiro (00144527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
91. Sobue Gen (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. Hasegawa Toshikazu (30172894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
93. Ota Jun (50233127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
94. Saitoe Minoru (50261839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. Kadomatsu Kenji (80204519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
96. Kida Satoshi (80301547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
97. Manabe Toshiya (70251212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
98. Tomita Taisuke (30292957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
99. Iwata Atsushi (40401038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
100. Murakami Ikuya (60396166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
101. Tsutsui Ken-ichiro (90396466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
102. Hanakawa Takashi (30359830)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
103. Mima Tatsuya (20324618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
104. Isomura Yoshikazu (00415077)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
105. Samejima Kazuyuki (30395131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
106. Hoshi Eiji (50407681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
107. Miyata Mariko (70281631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
108. Yuzaki Michisuke (40365226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
109. Tanaka Masaki (90301887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
110. Fukata Masaki (00335027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
111. Suzuki Kyoko (20271934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
112. Kuba Hiroshi (10362469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
113. Masu Masayuki (20243032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
114. Kinoshita Makoto (30273460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
115. Sugihara Izumi (60187656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
116. Shirane Michiko (90398082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
117. Yamamoto Nobuhiko (00191429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
118. Nishijo Hisao (00189284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
119. Nambu Atsushi (80180553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
120. Takumi Toru (00222092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
121. Yamashita Toshihide (10301269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
122. Sakurai Takeshi (60251055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
123. Tamamaki Nobuaki (20155253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
124. Hata Yoshio (40212146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
125. Harada Akihiro (40251441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
126. Ozaki Norio (40281480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
127. Sakai Katsuyuki (70376416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
128. Kubo Yoshihiro (80211887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
129. Nakazawa Takanobu (00447335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
130. Tanaka Kenji (30329700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
131. Takei Nobuyuki (70221372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
132. Hitoshi Seiji (70300895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
133. Takahiroa. Kato (70546465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
134. Kato Fusao (20169519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
135. Shirao Tomoaki (20171043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
136. Taira Masato (50179397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
137. Okano Hideyuki (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
138. Sekino Yuko (70138866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
139. Okamoto Yasumasa (70314763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
140. KOMATSU Hidehiko (00153669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
141. Miyata Takaki (70311751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
142. Takahashi Yoshiko (10183857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
143. Nishida Shinya (20396162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
144. Tominaga Makoto (90260041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
145. Hirono Moritoshi (30318836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
146. MISONOU Hiroaki (40609509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
147. WATANABE Shoji (80462745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
148. 遠藤昌吾 (60192514)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
149. 小澤瀞司 (40049044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
150. 都筑馨介 (60222139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
151. 飯野昌枝 (20008329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
152. 石崎泰樹 (90183003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
153. 石内勝吾 (10312878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
154. 藤井正彦 (00228959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
155. 寅嶋崇 (40422646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
156. 寺田一志 (90227520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
157. 六本木麗子 (80719857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
158. MIYAZAKI Taisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. TAKARADA Mika

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
160. YASUDA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
161. YAMAMORI Hidenaga

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. TSUBOI Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
163. KITAGUCHI Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
164. KURAUCHI Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
165. 亀谷富由樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
166. 野中隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
167. 鈴木元治郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
168. 田中良法

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
169. 阿部学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
170. 白井良憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
171. 鈴木龍男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
172. 渡邉康春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirai Hirokazu 平井 宏和

HIRAI Hirokazu 平井 宏和

平井 宏和 ヒライ ヒロカズ

Research Projects

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Co-Researchers

Development of microglia-targeting AAV vectors and its application to neurodegenerative disordersPrincipal Investigator

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Gene therapy against Rett syndrome and functional analysis of MeCP2, using blood-brain barrier-penetrating AAV vectorsPrincipal Investigator

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Development of gene therapy against neurodegenerative diseases using CRISPR/Cas9-based genome editingPrincipal Investigator

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Elucidation of cellular and nuclear signals that regulate motor learningPrincipal Investigator

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間葉系幹細胞による脳内環境の維持および破綻からの回復メカニズムの解明Principal Investigator

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デルタ2グルタミン酸受容体のNTDを介する新しい活性化様式の解明Principal Investigator

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Establishment and application of lentivector-based production of gene-rescue mouse for exploring gene functionsPrincipal Investigator

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デルタ2グルタミン酸受容体の細胞内信号伝達経路の解明Principal Investigator

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小脳プルキンエ細胞特異的薬剤誘導性ポリグルタミン産生マウスの作出と解析Principal Investigator

Principal Investigator

Hirai Hirokazu 平井宏和

HIRAI Hirokazu 平井宏和

平井宏和ヒライヒロカズ

[Book] ブレインサイエンスレビュー2007