saeki yasushi 佐伯泰

… Alternative Names

SAEKI Yasushi 佐伯泰

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Researcher Number	80462779
Other IDs
Affiliation (Current)	2025: 東京大学, 医科学研究所, 教授 2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京大学, 医科学研究所, 教授 2020 – 2023: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, プロジェクトリーダー 2013 – 2019: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 副参事研究員 2018: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 室長 2017: 東京都医学総合研究所, 蛋白質代謝研究室, 副参事研究員 … More 2013 – 2016: 公益財団法人東京都医学総合研究所, その他部局等, その他 2013: 公益財団法人東京都医学総合研究所, 吉田化学遺伝学研究室, 主席研究員 2011 – 2013: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2012: 公益財団法人東京都医学総合研究所, その他部局等, 研究員 2012: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席事研究員 2012: 公益財団法人東京都医学総合研究所, 生体分子専担研究分野, 主席研究員 2011: (財)東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2011: 財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2010: (財)東京都医学総合研究所, 東京都臨床医学総合研究所, 主任研究員 2010: (財)東京都医学総合研究所, 蛋白質代謝研究室, 主席研究員 2010: 財団法人東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2009 – 2010: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主席研究員 2009: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 主任研究員 2008: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Complex systems / Functional biochemistry / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Biological pharmacy / Biological Sciences / Broad Section G / Transformative Research Areas, Section (III) Except Principal Investigator Animal production science / Transformative Research Areas, Section (III) / General medical chemistry … More / Biological Sciences / Applied animal science / Biological Sciences / Biophysics Less
Keywords	Principal Investigator ユビキチン / プロテアソーム / タンパク質分解 / 細胞内タンパク質分解 / 質量分析 / プロテオーム / 酵母 / 酵素 / 蛋白質 / 質量分析計 … More / 液－液相分離 / ステープルペプチド / 標的タンパク質分解誘導剤 / 翻訳後修飾 / ケミカルバイオロジー / 生体分子 / 微生物 / 蛋白質分解 / 人工抗体 / タンパク質分解誘導剤 / プロテアソーム病 / タンパク質寿命 / 細胞分化 / ケモテクノロジー / p97 / シグナル伝達 / タンパク質化学合成 / 不良新生鎖 / プロテオミクス / 核外輸送 / 細胞質核間輸送 / クロマチン構造 / 転写 / 遺伝子 / ストレス応答 / 核内構造体 / 細胞 / タンパク質品質管理 / リボソーム / ATP / ミトコンドリア / 蛍光相関分光法 / 可逆性顆粒 / アフィニティープローブ / 定量プロテオミクス / 脱ユビキチン化酵素 / 細胞質核間輸送担体 … More Except Principal Investigator インスリン受容体基質 / ユビキチン / インスリン / インスリン様活性 / インスリン様成長因子 / 代謝・内分泌制御 / がん / 糖尿病 / 増殖 / ユビキチンリガーゼ / 細胞内シグナル / 脱ユビキチン化酵素 / タンパク質分解 / 酵母 / プロテアソーム / 若手育成 / ケミカルバイオロジー / 標的タンパク質分解 / 質量分析 / タンパク質寿命 / 成長異常 / インスリン抵抗性 / 糖取り込み / スプライシング / 翻訳 / 細胞内シグナル伝達 / 翻訳後修飾 / タンパク質 / 生体分子 / 研究技法共有 / 国際化推進 / 若手支援 / 情報交換 / 領域内研究者交流 / インスリン様成長因子受容体 / アダプタータンパク質 / ユビキチン化酵素 / 温度感受性 / 相互作用 / 拡散定数 / 絶対濃度 / 蛍光相関分光法 / 細胞質と核 / 核移行 / 26S複合体 / 生細胞イメージング / 画像解析 / 三次元再構成 / 電子顕微鏡 / 単粒子解析 / 構造生物学 Less

プロテアソームとユビキチンコードの統合的解析Principal Investigator
- Principal Investigator
  
  佐伯泰
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Shin-biology regulated by protein lifetime
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Mechanism of how the proteasome determines protein lifetimePrincipal Investigator
- Principal Investigator
  
  佐伯泰
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
Integrated understanding of proteasomal degradation and the ubiquitin codePrincipal Investigator
- Principal Investigator
  
  佐伯泰
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  The University of Tokyo
New Frontier for Ubiquitin Biology Driven by Chemo-technologiesPrincipal Investigator
- Principal Investigator
  
  佐伯泰
- Project Period (FY)
  2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
New frontier for ubiquitin biology driven by chemo-technologiesArea Organizer
- Area Organizer
  
  佐伯泰
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
New frontier for ubiquitin biology driven by chemo-technologiesPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Decryption of the ubiquitin code by chemo-technologies and advanced proteomicsPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of protein networks controlling proteasomal degradationPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of degradation signals presented on aberrant nascent polypeptidesPrincipal Investigator
- Principal Investigator
  
  佐伯泰
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Elucidation of the mechanism for nuclear export of the proteasomePrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Formation mechanism and physiological significance of proteasome specklePrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Roles of Nedd4-IRS complexes in the development of diabetes and cancer
- Principal Investigator
  
  Fukushima Toshiaki
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Institute of Technology
  Hiroshima University
Development of methods to regulate abnormality of insulin-like activity by modulation of function of insulin receptor substrates-associated complex
- Principal Investigator
  
  Takahashi Shin-Ichiro
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Animal production science
- Research Institution
  The University of Tokyo
動物の一生において時期・組織特異的にインスリン様活性を制御する新規機構とその意義
- Principal Investigator
  
  高橋伸一郎
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Animal production science
- Research Institution
  The University of Tokyo
New aspect of the ubiquitin system : its enormous roles in protein regulation
- Principal Investigator
  
  IWAI Kazuhiro
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Development of biochemical methods to understand protein ubiquitylationPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Formation mechanism of proteasome granulesPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Novel mechanisms of growth regulation through changes in ubiquitination of insulin receptor substrates
- Principal Investigator
  
  TAKAHASHI Shin-Ichiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied animal science
- Research Institution
  The University of Tokyo
Mechanism of the proteasome nuclear localizationPrincipal Investigator
- Principal Investigator
  
  SAEKI Yasushi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
Characterization of deubiquitylating enzymes in yeastPrincipal Investigator
- Principal Investigator
  
  YASUSHI Saeki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  公益財団法人東京都医学総合研究所
   Tokyo Metropolitan Organization for Medical Research
蛍光相関分光法を用いたプロテアソームの時空間的制御機構の解析
- Principal Investigator
  
  白燦基
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research
Structural study of proteasome by single particle analysis
- Principal Investigator
  
  MITSUOKA Kaoru
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  National Institute of Advanced Industrial Science and Technology

[Book] 実験医学別冊『決定版質量分析活用スタンダード』2023
- Author(s)
  佐伯泰、土屋光、遠藤彬則、冨田拓哉
- Total Pages
  11
- Publisher
  羊土社
- ISBN
  9784758122641
- Data Source
  KAKENHI-PLANNED-23H04921
[Book] 実験医学別冊『決定版質量分析活用スタンダード』2023
- Author(s)
  佐伯泰、土屋光、遠藤彬則、冨田拓哉
- Total Pages
  11
- Publisher
  羊土社
- ISBN
  9784758122641
- Data Source
  KAKENHI-PROJECT-23H05479
[Book] ユビキチン修飾と相分離2021
- Author(s)
  佐伯　泰
- Total Pages
  8
- Publisher
  羊土社
- ISBN
  9784758103954
- Data Source
  KAKENHI-PLANNED-18H05498
[Book] 相分離　メカニズムと疾患2021
- Author(s)
  佐伯泰
- Total Pages
  8
- Publisher
  羊土社
- ISBN
  9784758103954
- Data Source
  KAKENHI-PROJECT-18H03993
[Book] イメージング時代の構造生命科学2020
- Author(s)
  安田さや香、田中啓二、佐伯泰
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758103855
- Data Source
  KAKENHI-PLANNED-18H05498
[Book] 相分離生物学の全貌2020
- Author(s)
  土屋光、佐伯泰
- Total Pages
  5
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-18H03993
[Book] イメージング時代の構造生命科学2020
- Author(s)
  安田さや香、田中啓二、佐伯泰
- Total Pages
  6
- Publisher
  羊土社
- ISBN
  9784758103855
- Data Source
  KAKENHI-PROJECT-18H03993
[Book] 実験医学2017
- Author(s)
  佐伯泰、土屋光、大竹史明、田中啓二
- Total Pages
  8
- Publisher
  羊土社
- ISBN
  9784758125000
- Data Source
  KAKENHI-PROJECT-26293018
[Book] 生物物理「プロテアソームの細胞内動態と機能」2015
- Author(s)
  佐伯泰
- Total Pages
  4
- Publisher
  日本生物物理学会
- Data Source
  KAKENHI-PROJECT-26293018
[Book] 実験医学・増刊号「構造生命科学－構造を使う研究を目指す新しいライフサイエンス」2014
- Author(s)
  佐伯泰、水島恒裕
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-24112008
[Book] 実験医学・増刊号「構造生命科学－構造を使う研究を目指す新しいライフサイエンス」2014
- Author(s)
  佐伯泰、水島恒裕
- Total Pages
  7
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] プロテアソームの作動機構とダイナミクス「構造生命科学で何がわかるのか何ができるのか」実験医学・増刊号32巻(10号)2014
- Author(s)
  佐伯泰,水島恒裕
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] 細胞工学HOT PRESS「プロテアソームの細胞内ダイナミクス」2014
- Author(s)
  佐伯泰，白燦基
- Total Pages
  3
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-26293018
[Book] 実験医学・増刊号「構造生命科学で何がわかるのか何ができるのか」2014
- Author(s)
  佐伯泰，水島恒裕
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26293018
[Book] 細胞工学Hot Press2014
- Author(s)
  佐伯泰、白燦基
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PLANNED-24112008
[Book] 細胞工学「Hot Press」2014
- Author(s)
  佐伯　泰、白　燦基
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] 巨大で複雑な蛋白分解装置の立体構造と活性調節機構.「特集/蛋白構造-機能連関解析と治療薬開発への応用」内分泌・糖尿病・代謝内科、第35巻12月号2012
- Author(s)
  佐伯泰
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] 特集／蛋白構造－機能連関解析と治療薬開発への応用」内分泌・糖尿病・代謝内科2012
- Author(s)
  佐伯泰
- Total Pages
  10
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] The proteasome: molecular machinery and pathophysiological roles. Biol. Chem. 3932012
- Author(s)
  Tanaka, K., Mizushima, N., and Saeki, Y
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 細胞膜修復機構におけるプロテアソームの役割.細胞工学31巻2012
- Author(s)
  河野恵子,佐伯泰,吉田知史,田中啓二,David Pellman
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] 巨大で複雑な蛋白分解装置の立体構造と活性調節機構.「特集/蛋白構造-機能連関解析と治療薬開発への応用」内分泌・糖尿病・代謝内科、第35巻12月号2012
- Author(s)
  佐伯泰
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 細胞工学31巻2012
- Author(s)
  河野恵子，佐伯泰，吉田知史，田中啓二，David Pellman
- Total Pages
  2
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] Assembly and function of the proteasome. (Ubiquitin family modifiers and the proteasome)2012
- Author(s)
  Saeki, Y. and Tanaka, K. Review
- Publisher
  Humana Press, Methods Mol. Biol. 832
- Data Source
  KAKENHI-PROJECT-22687009
[Book] タンパク質分解研究による生態防御2012
- Author(s)
  佐伯泰
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22657037
[Book] Ubiquitin Family Modifiers and the Proteasome2012
- Author(s)
  Saeki, Y., Tanaka, K.
- Total Pages
  22
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-22687009
[Book] タンパク質分解研究による生態防御2012
- Author(s)
  佐伯泰
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] Ubiquitin Family Modifiers and the Proteasome2012
- Author(s)
  Saeki, Y., Tanaka, K.
- Total Pages
  22
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-22657037
[Book] 細胞膜修復機構におけるプロテアソームの役割.細胞工学31巻2012
- Author(s)
  河野恵子,佐伯泰,吉田知史,田中啓二,David Pellman
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 「特集／蛋白構造－機能連関解析と治療薬開発への応用」内分泌・糖尿病・代謝内科2012
- Author(s)
  佐伯泰
- Total Pages
  10
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-24657097
[Book] 「特集／蛋白構造－機能連関解析と治療薬開発への応用」内分泌・糖尿病・代謝内科2012
- Author(s)
  佐伯泰
- Total Pages
  10
- Publisher
  科学評論社
- Data Source
  KAKENHI-PLANNED-24112008
[Book] みえてきた26Sプロテアソームの形成機構の全貌,「細胞内分解系によるリノベーションの分子機構に迫る」実験医学・増刊号29巻(12号)2011
- Author(s)
  佐伯泰
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 実験医学・増刊号(細胞内分解系によるリノベーションの分子機構に迫る)2011
- Author(s)
  佐伯泰、福永圭佑
- Publisher
  羊土社印刷中
- Data Source
  KAKENHI-PROJECT-22657037
[Book] 実験医学・増刊号「細胞内分解系によるリノベーションの分子機構に迫る」2011
- Author(s)
  佐伯泰、福永圭佑
- Publisher
  羊土社(印刷中)
- Data Source
  KAKENHI-PROJECT-22687009
[Book] Methods in Molecular Biology (Ubiquitin family modifiers and the proteasome)2011
- Author(s)
  Saeki, Y., Tanaka, K.
- Publisher
  Humana Press 印刷中
- Data Source
  KAKENHI-PROJECT-22657037
[Book] 脱ユビキチン化酵素Ubp6はプロテアソームの分子集合を制御する2011
- Author(s)
  佐伯泰,田中啓二
- Publisher
  ライフサイエンス「新着論文レビュー」
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 脱ユビキチン化酵素Ubp6はプロテアソームの分子集合を制御する.ライフサイエンス「新着論文レビュー」2011
- Author(s)
  佐伯泰,田中啓二
- URL
  http://first.lifesciencedb.jp/archives/3121
- Data Source
  KAKENHI-PROJECT-22657037
[Book] 実験医学・増刊号「細胞内分解系によるリノベーションの分子機構に迫る」2011
- Author(s)
  佐伯泰
- Publisher
  羊土社(印刷中)
- Data Source
  KAKENHI-PUBLICLY-21025038
[Book] Methods in Molecular Biology (Ubiquitin family modifiers and the proteasome)2011
- Author(s)
  Saeki, Y.
- Publisher
  Humana Press(In press)
- Data Source
  KAKENHI-PUBLICLY-21025038
[Book] Methods in Molecular Biology (Ubiquitin family modifiers and the proteasome)2011
- Author(s)
  Saeki, Y., Tanaka, K.
- Publisher
  Humana Press(印刷中)
- Data Source
  KAKENHI-PROJECT-22687009
[Book] みえてきた26Sプロテアソームの形成機構の全貌,「細胞内分解系によるリノベーションの分子機構に迫る」実験医学2011
- Author(s)
  佐伯泰,福永圭佑
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22657037
[Book] 日本臨牀特集分子標的薬治療2010
- Author(s)
  佐伯泰、福永圭佑、田中啓二
- Total Pages
  5
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22687009
[Book] 日本臨牀分子標的薬治療2010
- Author(s)
  佐伯泰
- Total Pages
  6
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PUBLICLY-21025038
[Book] 日本臨牀特集分子標的薬治療2010
- Author(s)
  佐伯泰、福永圭佑、田中啓二
- Total Pages
  5
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22657037
[Book] プロテアソーム阻害剤. 日本臨牀, 682010
- Author(s)
  佐伯泰, 福永圭佑, 田中啓二:
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] USP8 prevents aberrant NF-kappaB and Nrf2 activation by counteracting ubiquitin signals from endosomes.2024
- Author(s)
  Endo A, Fukushima T, Takahashi C, Tsuchiya H, Ohtake F, Ono S, Ly T, Yoshida Y, Tanaka K, Saeki Y, Komada M.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 223(3) Issue: 3 Pages: 1-1
- DOI
  10.1083/jcb.202306013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06039, KAKENHI-ORGANIZER-23H04917, KAKENHI-PLANNED-23H04921, KAKENHI-PROJECT-23H05479, KAKENHI-PROJECT-22H00419, KAKENHI-PROJECT-23K23571
[Journal Article] Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics2023
- Author(s)
  Tsumagari Kazuya、Isobe Yosuke、Ishihama Yasushi、Seita Jun、Arita Makoto、Imami Koshi
- Journal Title
  
  Molecular & Cellular Proteomics
  
  Volume: 22 Issue: 12 Pages: 100677-100677
- DOI
  10.1016/j.mcpro.2023.100677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14169, KAKENHI-ORGANIZER-23H04917, KAKENHI-PROJECT-20H03241
[Journal Article] Senescent cells form nuclear foci that contain the 26S proteasome2023
- Author(s)
  Iriki Tomohiro、Iio Hiroaki、Yasuda Shu、Masuta Shun、Kato Masakazu、Kosako Hidetaka、Hirayama Shoshiro、Endo Akinori、Ohtake Fumiaki、Kamiya Mako、Urano Yasuteru、Saeki Yasushi、Hamazaki Jun、Murata Shigeo
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 8 Pages: 112880-112880
- DOI
  10.1016/j.celrep.2023.112880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18107, KAKENHI-PROJECT-22K06611, KAKENHI-WRAPUP-23H05424, KAKENHI-ORGANIZER-23H04917, KAKENHI-PLANNED-23H04918, KAKENHI-PLANNED-23H04921, KAKENHI-PROJECT-23H05479, KAKENHI-PROJECT-22H00402
[Journal Article] An attenuated vaccinia vaccine encoding the severe acute respiratory syndrome coronavirus-2 spike protein elicits broad and durable immune responses, and protects cynomolgus macaques and human angiotensin-converting enzyme 2 transgenic mice from severe acute respiratory syndrome coronavirus-2 and its variants.2022
- Author(s)
  Ishigaki H, Yasui F, Nakayama M, Endo A, Yamamoto N, Yamaji K, Nguyen CT, Kitagawa Y, Sanada T, Honda T, Munakata T, Higa M, Toyama S, Kono R, Takagi A, Matsumoto Y, Koseki A, Hayashi K, Shiohara M, Ishii K, Saeki Y, Itoh Y, Kohara M.
- Journal Title
  
  Front Microbiol.
  
  Volume: 13 Pages: 967019-967019
- DOI
  10.3389/fmicb.2022.967019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07531, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-20K08838, KAKENHI-PLANNED-18H05498
[Journal Article] ABIN1 is a signal‐induced autophagy receptor that attenuates NF‐κB activation by recognizing linear ubiquitin chains2022
- Author(s)
  Shinkawa Y, Imami K, Fuseya Y, Sasaki K, Ohmura K, Ishihama Y, Morinobu A, Iwai K.
- Journal Title
  
  FEBS Letters
  
  Volume: In press Issue: 9 Pages: 1147-1164
- DOI
  10.1002/1873-3468.14323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05499, KAKENHI-PUBLICLY-20H04844, KAKENHI-PUBLICLY-21H05720, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-20H03241, KAKENHI-PROJECT-20K07337, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-22K15379
[Journal Article] cIAP1-based degraders induce degradation via branched ubiquitin architectures2022
- Author(s)
  Akizuki Yoshino、Morita Mai、Mori Yuki、Kaiho-Soma Ai、Dixit Shivani、Endo Akinori、Shimogawa Marie、Hayashi Gosuke、Naito Mikihiko、Okamoto Akimitsu、Tanaka Keiji、Saeki Yasushi、Ohtake Fumiaki
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 19 Issue: 3 Pages: 311-322
- DOI
  10.1038/s41589-022-01178-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00419, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K19040, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PLANNED-18H05504, KAKENHI-PROJECT-21H02777
[Journal Article] ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer2022
- Author(s)
  Takumi Tsunoda, Miho Riku, Norika Yamada, Hikaru Tsuchiya, Takuya Tomita, Minako Suzuki, Mari Kizuki, Akihito Inoko, Hideaki Ito, Kenta Murotani, Hideki Murakami, Yasushi Saeki, Kenji Kasai
- Journal Title
  
  EMBO reports
  
  Volume: 23 Issue: 2
- DOI
  10.15252/embr.202051182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07449, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-19K06671, KAKENHI-PROJECT-20K16182, KAKENHI-PROJECT-20K16205
[Journal Article] The TGN/EE SNARE protein SYP61 and the ubiquitin ligase ATL31 cooperatively regulate plant responses to carbon/nitrogen conditions in Arabidopsis2022
- Author(s)
  Yoko Hasegawa, Thais Huarancca Reyes, Tomohiro Uemura, Anirban Baral, Akari Fujimaki, Yongming Luo, Yoshie Morita, Yasushi Saeki, Shugo Maekawa, Shigetaka Yasuda, Koki Mukuta, Yoichiro Fukao, Keiji Tanaka, Akihiko Nakano, Junpei Takagi, Rishikesh P Bhalerao, Junji Yamaguchi, Takeo Sato
- Journal Title
  
  THE PLANT CELL
  
  Volume: 34 Issue: 4 Pages: 1354-1374
- DOI
  10.1093/plcell/koac014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14728, KAKENHI-PROJECT-18KK0196, KAKENHI-PROJECT-18H02162, KAKENHI-PLANNED-17H06420, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-21J11970, KAKENHI-PROJECT-20K05949, KAKENHI-PROJECT-21K14825, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-22K05563, KAKENHI-PROJECT-21K14829, KAKENHI-PROJECT-18H05275, KAKENHI-PUBLICLY-21H05644, KAKENHI-PROJECT-21H02150, KAKENHI-ORGANIZER-18H05497, KAKENHI-WRAPUP-22H04899
[Journal Article] MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL2021
- Author(s)
  Nakabayashi Osamu、Takahashi Hirotaka、Moriwaki Kenta、Komazawa-Sakon Sachiko、Ohtake Fumiaki、Murai Shin、Tsuchiya Yuichi、Koyahara Yuki、Saeki Yasushi、Yoshida Yukiko、Yamazaki Soh、Tokunaga Fuminori、Sawasaki Tatsuya、Nakano Hiroyasu
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 80-80
- DOI
  10.1038/s42003-020-01603-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07399, KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-20K05238, KAKENHI-PROJECT-20K06611, KAKENHI-PROJECT-20K11589, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PUBLICLY-19H05292, KAKENHI-PROJECT-19H02926, KAKENHI-PROJECT-19H03218, KAKENHI-PROJECT-20H03475, KAKENHI-PROJECT-20K09231, KAKENHI-PROJECT-19K22541, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-18H02619, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-21H02688, KAKENHI-PROJECT-16H06276
[Journal Article] RNA polymerase II condensate formation and association with Cajal and histone locus bodies in living human cells2021
- Author(s)
  Imada Takashi、Shimi Takeshi、Kaiho Ai、Saeki Yasushi、Kimura Hiroshi
- Journal Title
  
  Genes to Cells
  
  Volume: - Issue: 5 Pages: 298-312
- DOI
  10.1111/gtc.12840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H01417, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05527, KAKENHI-PROJECT-18H03993
[Journal Article] Frontier of the ubiquitin code research2021
- Author(s)
  佐伯泰、遠藤彬則、大竹史明
- Journal Title
  
  MEDCHEM NEWS
  
  Volume: 31 Issue: 3 Pages: 136-142
- DOI
  10.14894/medchem.31.3_136
- NAID
  130008070855
- ISSN
  2432-8618, 2432-8626
- Year and Date
  2021-08-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05498
[Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021
- Author(s)
  Yokoo Hidetomo、Shibata Norihito、Endo Akinori、Ito Takahito、Yanase Yuta、Murakami Yuki、Fujii Kiyonaga、Hamamura Kengo、Saeki Yasushi、Naito Mikihiko、Aritake Kosuke、Demizu Yosuke
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Issue: 21 Pages: 15868-15882
- DOI
  10.1021/acs.jmedchem.1c01206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K07311, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-21K11613, KAKENHI-PROJECT-20K22711
[Journal Article] TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains2021
- Author(s)
  Kaiho-Soma Ai、Akizuki Yoshino、Igarashi Katsuhide、Endo Akinori、Shoda Takuji、Kawase Yasuko、Demizu Yosuke、Naito Mikihiko、Saeki Yasushi、Tanaka Keiji、Ohtake Fumiaki
- Journal Title
  
  Molecular Cell
  
  Volume: 81 Issue: 7 Pages: 1411-1424.e7
- DOI
  10.1016/j.molcel.2021.01.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07009, KAKENHI-PROJECT-17H01882, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-20K22726, KAKENHI-PROJECT-17H03986, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-21H03604, KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-20K21408
[Journal Article] 最先端プロテオミクス解析を用いたユビキチン研究2020
- Author(s)
  佐伯泰
- Journal Title
  
  Farumashia
  
  Volume: 56 Issue: 1 Pages: 21-25
- DOI
  10.14894/faruawpsj.56.1_21
- NAID
  130007779041
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-ORGANIZER-18H05497
[Journal Article] Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses.2020
- Author(s)
  Oikawa D, Sato Y, Ohtake F, Komakura K, Hanada K, Sugawara K, Terawaki S, Mizukami Y, Phuong HT, Iio K, Obika S, Fukushi M, Irie T, Tsuruta D, Sakamoto S, Tanaka K, Saeki Y, Fukai S, Tokunaga F.
- Journal Title
  
  Commun. Biol.
  
  Volume: 3 Issue: 1 Pages: 163-163
- DOI
  10.1038/s42003-020-0882-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22541, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-18H05501, KAKENHI-PROJECT-18H02619, KAKENHI-PROJECT-17K19560, KAKENHI-PROJECT-19K22968, KAKENHI-PLANNED-16H06575, KAKENHI-PUBLICLY-19H04837, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K06937, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-18H05497
[Journal Article] Proteasome phase separation for degradation2020
- Author(s)
  佐伯泰、安田さや香、土屋光
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 6 Pages: 822-826
- DOI
  10.14952/SEIKAGAKU.2020.920822
- NAID
  40022454281
- ISSN
  0037-1017
- Year and Date
  2020-12-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03993, KAKENHI-PLANNED-18H05498
[Journal Article] Ribosomal protein S7 ubiquitination during ER stress in yeast is associated with selective mRNA translation and stress outcome2020
- Author(s)
  Matsuki Yasuko、Matsuo Yoshitaka、Nakano Yu、Iwasaki Shintaro、Yoko Hideyuki、Udagawa Tsuyoshi、Li Sihan、Saeki Yasushi、Yoshihisa Tohru、Tanaka Keiji、Ingolia Nicholas T.、Inada Toshifumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19669-19669
- DOI
  10.1038/s41598-020-76239-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06481, KAKENHI-PROJECT-20K06490, KAKENHI-PUBLICLY-19H05281, KAKENHI-PROJECT-18H03977, KAKENHI-PROJECT-19H00997, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04998, KAKENHI-PROJECT-19K22406, KAKENHI-PLANNED-20H05784
[Journal Article] α-synuclein strains that cause distinct pathologies differentially inhibit proteasome2020
- Author(s)
  Suzuki Genjiro、Imura Sei、Hosokawa Masato、Katsumata Ryu、Nonaka Takashi、Hisanaga Shin-Ichi、Saeki Yasushi、Hasegawa Masato
- Journal Title
  
  eLife
  
  Volume: 9
- DOI
  10.7554/elife.56825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06942, KAKENHI-PROJECT-18H03993, KAKENHI-PLANNED-18H05498, KAKENHI-ORGANIZER-18H05497
[Journal Article] Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation2020
- Author(s)
  A. Nishiyama, C. Mulholland, S. Bultmann, S. Kori, A. Endo, Y. Saeki, W. Qin, C. Trummer, Y. Chiba, H. Yokoyama, S. Kumamoto, T. Kawakami, H. Hojo, G. Nagae, H. Aburatani, K. Tanaka, K. Arita, H. Leonhardt, M. Nakanishi
- Journal Title
  
  Nat. Commun.
  
  Volume: 11 Issue: 1 Pages: 1222-1222
- DOI
  10.1038/s41467-020-15006-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05316, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PUBLICLY-19H05285, KAKENHI-PLANNED-19H05744, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H02392, KAKENHI-PROJECT-19H03153, KAKENHI-PROJECT-19J22030, KAKENHI-PLANNED-19H05740, KAKENHI-PROJECT-17H01398, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K07963, KAKENHI-ORGANIZER-19H05739
[Journal Article] A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets2020
- Author(s)
  Watanabe Masashi、Saeki Yasushi、Takahashi Hidehisa、Ohtake Fumiaki、Yoshida Yukiko、Kasuga Yusuke、Kondo Takeshi、Yaguchi Hiroaki、Suzuki Masanobu、Ishida Hiroki、Tanaka Keiji、Hatakeyama Shigetsugu
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 592-592
- DOI
  10.1038/s42003-020-01328-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-19K22401, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-17H03986, KAKENHI-ORGANIZER-18H05497
[Journal Article] Stress- and ubiquitylation-dependent phase separation of the proteasome2020
- Author(s)
  Yasuda Sayaka、Tsuchiya Hikaru、Kaiho Ai、Guo Qiang、Ikeuchi Ken、Endo Akinori、Arai Naoko、Ohtake Fumiaki、Murata Shigeo、Inada Toshifumi、Baumeister Wolfgang、Fernandez-Busnadiego Ruben、Tanaka Keiji、Saeki Yasushi
- Journal Title
  
  Nature
  
  Volume: 578 Issue: 7794 Pages: 296-300
- DOI
  10.1038/s41586-020-1982-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05500, KAKENHI-PUBLICLY-19H05281, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-18K14913, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-19H00997
[Journal Article] RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD12020
- Author(s)
  Matsuo Yoshitaka、Tesina Petr、Nakajima Shizuka、Mizuno Masato、Endo Akinori、Buschauer Robert、Cheng Jingdong、Shounai Okuto、Ikeuchi Ken、Saeki Yasushi、Becker Thomas、Beckmann Roland、Inada Toshifumi
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 27 Issue: 4 Pages: 323-332
- DOI
  10.1038/s41594-020-0393-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06481, KAKENHI-PLANNED-18H05498, KAKENHI-PUBLICLY-19H05281, KAKENHI-PROJECT-18H03977, KAKENHI-PROJECT-18H03993, KAKENHI-ORGANIZER-18H05497
[Journal Article] The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC2020
- Author(s)
  Fuseya Yasuhiro、Fujita Hiroaki、Kim Minsoo、Ohtake Fumiaki、Nishide Akira、Sasaki Katsuhiro、Saeki Yasushi、Tanaka Keiji、Takahashi Ryosuke、Iwai Kazuhiro
- Journal Title
  
  Nature Cell Biology
  
  Volume: 22 Issue: 6 Pages: 663-673
- DOI
  10.1038/s41556-020-0517-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16144, KAKENHI-PLANNED-18H05499, KAKENHI-PROJECT-17H06174, KAKENHI-PROJECT-19H00997, KAKENHI-PLANNED-18H05498, KAKENHI-PUBLICLY-20H05319, KAKENHI-PROJECT-17H03986, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-19K06635, KAKENHI-PUBLICLY-20H05505
[Journal Article] A novel method to determine the chain length of the polyubiquitinated proteins2020
- Author(s)
  土屋光、佐伯泰
- Journal Title
  
  生化学
  
  Volume: 92 Issue: 1 Pages: 14-19
- DOI
  10.14952/SEIKAGAKU.2020.920014
- ISSN
  0037-1017
- Year and Date
  2020-02-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-ORGANIZER-18H05497
[Journal Article] Multi-Step Ubiquitin Decoding Mechanism for Proteasomal Degradation2020
- Author(s)
  Tsuchiya Hikaru、Endo Akinori、Saeki Yasushi
- Journal Title
  
  Pharmaceuticals
  
  Volume: 13 Issue: 6 Pages: 128-128
- DOI
  10.3390/ph13060128
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03993, KAKENHI-PLANNED-18H05498, KAKENHI-ORGANIZER-18H05497
[Journal Article] Stepwise multipolyubiquitination of p53 by the E6AP-E6 ubiquitin ligase complex2019
- Author(s)
  Masuda Y, Saeki Y, Arai N, Kawai H, Kukimoto I, Tanaka K, Masutani C.
- Journal Title
  
  J Biol Chem
  
  Volume: 294 Issue: 41 Pages: 14860-14875
- DOI
  10.1074/jbc.ra119.008374
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11309, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-16H01775, KAKENHI-PROJECT-17H00785, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H03371, KAKENHI-PROJECT-20K20310
[Journal Article] Detection of ubiquitination activity and identification of ubiquitinated substrates using TR-TUBE2019
- Author(s)
  Yoshida, Y., Saeki, Y., Tsuchiya, H., and Tanaka, K.
- Journal Title
  
  Methods Enzymol
  
  Volume: 618 Pages: 135-147
- DOI
  10.1016/bs.mie.2018.12.032
- ISBN
  9780128163597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14913, KAKENHI-ORGANIZER-18H05497, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-16K07705, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-19H02926, KAKENHI-PROJECT-26000014
[Journal Article] Structural insights into ubiquitin recognition and Ufd1 interaction of Npl42019
- Author(s)
  Sato Yusuke、Tsuchiya Hikaru、Yamagata Atsushi、Okatsu Kei、Tanaka Keiji、Saeki Yasushi、Fukai Shuya
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 5708-5708
- DOI
  10.1038/s41467-019-13697-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05501, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-19H03162, KAKENHI-PROJECT-18K14913, KAKENHI-PROJECT-26000014
[Journal Article] Methods to measure ubiquitin chain length and linkage.2019
- Author(s)
  Ohtake, F., Tsuchiya, H., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Methods Enzymol
  
  Volume: 618 Pages: 105-133
- DOI
  10.1016/bs.mie.2018.12.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K14913, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-16K14702
[Journal Article] Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control　pathways2019
- Author(s)
  Ikeuchi Ken、Tesina Petr、Matsuo Yoshitaka、Sugiyama Takato、Cheng Jingdong、Saeki Yasushi、Tanaka Keiji、Becker Thomas、Beckmann Roland、Inada Toshifumi
- Journal Title
  
  The EMBO Journal
  
  Volume: 38 Issue: 5
- DOI
  10.15252/embj.2018100276
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21743, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-26116003, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014
[Journal Article] Specific modification of aged proteasomes revealed by tag-exchangeable knock-in mice.2018
- Author(s)
  Tomita, T., Hirayama, S., Sakurai, Y., Ohte, Y., Yoshihara, H., Saeki, Y., Hamazaki, J., and Murata, S.
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 39 Issue: 1
- DOI
  10.1128/mcb.00426-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-16K08228, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] HERC2 facilitates BLM and WRN helicase complex interaction with RPA to suppress G-quadruplex DNA.2018
- Author(s)
  Wu W, Rokutanda N, Takeuchi J, Lai Y, Maruyama R, Togashi Y, Nishikawa H, Arai N, Miyoshi Y,Suzuki N, Saeki Y, Tanaka K, Ohta T.
- Journal Title
  
  Cancer Res.
  
  Volume: 78 Issue: 22 Pages: 6371-6385
- DOI
  10.1158/0008-5472.can-18-1877
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08676, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-17H03585, KAKENHI-PROJECT-17K18336
[Journal Article] K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.2018
- Author(s)
  Ohtake, F., Tsuchiya, H., Saeki, Y., and Tanaka, K
- Journal Title
  
  PNAS
  
  Volume: 115 Issue: 7 Pages: 1401-1408
- DOI
  10.1073/pnas.1716673115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14702, KAKENHI-PROJECT-26293018, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-26000014
[Journal Article] Ub-ProT reveals global length and composition of protein ubiquitylation in cells2018
- Author(s)
  Tsuchiya, H., Burana, D., Ohtake, F., Arai, N., Kaiho, A., Komada, M., Tanaka,K., and Saeki, Y.
- Journal Title
  
  Nature Commun
  
  Volume: 9 Issue: 1 Pages: 524-524
- DOI
  10.1038/s41467-018-02869-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K14702, KAKENHI-PROJECT-26293018, KAKENHI-PUBLICLY-17H05681, KAKENHI-PROJECT-17H03986, KAKENHI-PROJECT-26000014
[Journal Article] Deubiquitylases USP5 and USP13 are recruited to and regulate heat-induced stress granules through their deubiquitylating activities2018
- Author(s)
  Xie Xuan、Matsumoto Shunsuke、Endo Akinori、Fukushima Toshiaki、Kawahara Hiroyuki、Saeki Yasushi、Komada Masayuki
- Journal Title
  
  Journal of Cell Science
  
  Volume: 131 Issue: 8 Pages: 210856-210856
- DOI
  10.1242/jcs.210856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08625, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-16K14699, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-18H03993, KAKENHI-PROJECT-17H03657
[Journal Article] Ubiquitination of stalled ribosome triggers ribosome-associated quality control2017
- Author(s)
  Matsuo Y, Ikeuchi K, Saeki Y, Iwasaki S, Schmidt C, Udagawa T, Sato F, Tsuchiya H, Becker T, Tanaka K, Ingolia NT, Beckmann R, Inada T
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 159-159
- DOI
  10.1038/s41467-017-00188-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07243, KAKENHI-PROJECT-26293018, KAKENHI-PLANNED-26116003, KAKENHI-PROJECT-16K18486, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-17H05679, KAKENHI-PROJECT-17H04998
[Journal Article] In vivo ubiquitin linkage-type analysis reveals that the Cdc48-Rad23/Dsk2 axis contributes to K48-linked chain specificity of the proteasome.2017
- Author(s)
  Tsuchiya, H., Ohtake, F., Arai, N., Kaiho, A., Yasuda, S., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Mol. Cell
  
  Volume: 66 Issue: 4 Pages: 488-502
- DOI
  10.1016/j.molcel.2017.04.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293018, KAKENHI-PROJECT-26000014
[Journal Article] Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP302017
- Author(s)
  Sato Yusuke、Okatsu Kei、Saeki Yasushi、Yamano Koji、Matsuda Noriyuki、Kaiho Ai、Yamagata Atsushi、Goto-Ito Sakurako、Ishikawa Minoru、Hashimoto Yuichi、Tanaka Keiji、Fukai Shuya
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 24 Issue: 11 Pages: 911-919
- DOI
  10.1038/nsmb.3469
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15072, KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-26293018, KAKENHI-PROJECT-16H04749, KAKENHI-PROJECT-16H04750, KAKENHI-PROJECT-15J10559, KAKENHI-PROJECT-16K18545, KAKENHI-PROJECT-26000014
[Journal Article] In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-linked Chain Specificity of the Proteasome.2017
- Author(s)
  Tsuchiya, H., Ohtake, F., Arai, N., Kaiho, A., Yasuda, S., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Mol Cell
  
  Volume: 印刷中
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293018
[Journal Article] HTLV-1 Tax induces formation of the active macromolecular IKK complex by generating Lys63- and Met1-linked hybrid polyubiquitin chains.2017
- Author(s)
  Shibata Y, Tokunaga F, Goto E, Komatsu G, Gohda J, Saeki Y, Tanaka K, Takahashi H, Sawasaki T, Inoue S, Oshiumi H, Seya T, Nakano H, Tanaka Y, Iwai K, and Inoue J.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 13 Issue: 12 Pages: e1006162-e1006162
- DOI
  10.1371/journal.ppat.1006162
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-15H01553, KAKENHI-PUBLICLY-16H01192, KAKENHI-PLANNED-16H06575, KAKENHI-PLANNED-16H06579, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-26290036, KAKENHI-PROJECT-15K15353, KAKENHI-PROJECT-15K18468, KAKENHI-PROJECT-15K08517, KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K15210, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin recognition by the proteasome.2017
- Author(s)
  Saeki, Y.
- Journal Title
  
  J. Biochem.
  
  Volume: 161 Pages: 113-124
- DOI
  10.1093/jb/mvw091
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-15K14958, KAKENHI-PROJECT-26293018
[Journal Article] In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-linked Chain Specificity of the Proteasome.2017
- Author(s)
  Tsuchiya, H., Ohtake, F., Arai, N., Kaiho, A., Yasuda, S., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Mol Cell
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112008
[Journal Article] Structure of the Dnmt1 reader module complexed with a unique two-mono-ubiquitin mark on histone H3 reveals the basis for DNA methylation maintenance.2017
- Author(s)
  Ishiyama S, Nishiyama A, Saeki Y, Moritsugu K Morimoto D, Yamaguchi L, Arai N, Matsumura R, Kawakami T, Mishima Y, Hojo H, Shimamura S, Ishikawa F, Tajima S, Tanaka K, Ariyoshi M, Shirakawa M, Ikeguchi M, Kidera A, Suetake I, Arita K, Nakanishi M
- Journal Title
  
  Mol Cell
  
  Volume: 68 Issue: 2 Pages: 350-360
- DOI
  10.1016/j.molcel.2017.09.037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14418, KAKENHI-PROJECT-16K14714, KAKENHI-PROJECT-16K18503, KAKENHI-PROJECT-26293018, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-16H04780, KAKENHI-PROJECT-16H04818, KAKENHI-PROJECT-15K05565, KAKENHI-PROJECT-15K18520, KAKENHI-PROJECT-26000014
[Journal Article] 分子標的薬「プロテアソーム阻害剤」2016
- Author(s)
  佐伯泰
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 4 Pages: 30-38
- Data Source
  KAKENHI-PROJECT-26293018
[Journal Article] 分子標的薬「プロテアソーム阻害剤」2016
- Author(s)
  佐伯泰
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 4 Pages: 30-38
- Data Source
  KAKENHI-PLANNED-24112008
[Journal Article] 分子標的薬「プロテアソーム阻害剤」2016
- Author(s)
  佐伯泰
- Journal Title
  
  腎臓内科・泌尿器科
  
  Volume: 4 Pages: 30-38
- Data Source
  KAKENHI-PROJECT-15K14958
[Journal Article] Ankrd13 family of ubiquitin-interacting motif-bearing proteins regulates VCP/p97-mediated lysosomal traffic of caveolin-1.2016
- Author(s)
  Burana, D., Yoshihara, H., Tanno, H., Yamamoto, A., Saeki, Y., Tanaka, K., and Komada, M.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 12 Pages: 6218-6231
- DOI
  10.1074/jbc.m115.710707
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112003, KAKENHI-PROJECT-15H04293, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-24112008
[Journal Article] The K48-K63 branched ubiquitin chain regulates NF-kappaB signaling2016
- Author(s)
  Ohtake F, Saeki Y, Ishido S, Kanno J, Tanaka K
- Journal Title
  
  Mol. Cell
  
  Volume: 64 Issue: 2 Pages: 251-266
- DOI
  10.1016/j.molcel.2016.09.014
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112003, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-24112004, KAKENHI-PROJECT-16K14702
[Journal Article] Roles of chondroitin sulfate proteoglycan 4 in fibrogenic/adipogenic differentiation in skeletal muscle tissues.2016
- Author(s)
  Takeuchi S, Nakano S, Nakamura K, Ozoe A, Chien P, Yoshihara H, Hakuno F, Matsuwaki T, Saeki Y, Takahashi S, Yamanouchi K, Nishihara M
- Journal Title
  
  Experimental Cell Research
  
  Volume: 347 Issue: 2 Pages: 367-377
- DOI
  10.1016/j.yexcr.2016.08.023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16J08006, KAKENHI-PROJECT-25292185, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-16H05041
[Journal Article] The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipocyte activator PPAR gamma.2015
- Author(s)
  Watanabe, M., Takahashi, H., Saeki, Y., Ozaki, T., Itoh, S., Suzuki, M., Mizushima, W., Tanaka, K. and Hatakeyama, S.
- Journal Title
  
  eLIFE
  
  Volume: 4
- DOI
  10.7554/elife.05615
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-15K15058, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24112008, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130, KAKENHI-PROJECT-26000014
[Journal Article] ユビキチンリガーゼ活性の簡便で効率的な検出方法2015
- Author(s)
  吉田雪子, 佐伯泰, 田中啓二
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 3003-3007
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112008
[Journal Article] Mutations in the deubiquitinase gene USP8 cause Cushing’s disease2015
- Author(s)
  Reincke M, Sbiera S, Hayakawa A, Theodoropoulou M, Osswald A, Beuschlein F, Meitinger T, Mizuno-Yamasaki E, Kawaguchi K, Saeki Y, Tanaka K, Wieland T, Graf E, Saeger W, Ronchi CL, Allolio B, Buchfelder M, Strom TM, Fassnacht M & Komada M
- Journal Title
  
  Nat. Genet.
  
  Volume: 47 Issue: 1 Pages: 31-38
- DOI
  10.1038/ng.3166
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112003, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26000014
[Journal Article] Nedd4-induced mono-ubiquitination of IRS-2 enhances IGF signaling and mitogenic activity.2015
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Fumihiko Hakuno, Jing Luan, Cunming Duan, Yasushi Saeki, Keiji Tanaka, Shun-Ichiro Iemura, TohruNatsume, Kazuhiro Chida, Yusuke Nakatsu, Hideaki Kamata, Tomoichiro Asano, and Shin-Ichiro Takahashi
- Journal Title
  
  Nature communications
  
  Volume: 6 Issue: 1 Pages: 6780-6780
- DOI
  10.1038/ncomms7780
- NAID
  120006348510
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24380152, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25850220, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PLANNED-24112008, KAKENHI-ORGANIZER-24115001, KAKENHI-PLANNED-24115007, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-15H04583, KAKENHI-PROJECT-26000014
[Journal Article] The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.2015
- Author(s)
  Morimoto D,Walinda E, Fukada H, Sou YS, Kageyama S, Hoshino M, Fujii T, Tsuchiya H, Saeki Y, Arita K, Ariyoshi M, Tochio H, Iwai K, Namba K, Komatsu M, Tanaka K, Shirakawa M.
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Issue: 1 Pages: 6116-6116
- DOI
  10.1038/ncomms7116
- NAID
  120005528125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-21121006, KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-25000013, KAKENHI-PLANNED-25111006, KAKENHI-PUBLICLY-25112514, KAKENHI-PLANNED-26119004, KAKENHI-PROJECT-26440025, KAKENHI-PROJECT-26860224, KAKENHI-PROJECT-25253019, KAKENHI-PROJECT-26000014
[Journal Article] Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation.2015
- Author(s)
  Koji Yamano, Bruno B. Queliconi, Fumika Koyano, Yasushi Saeki, Takatsugu Hirokawa, Keiji Tanaka§,and Noriyuki Matsuda
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 290 Issue: 42 Pages: 25199-25211
- DOI
  10.1074/jbc.m115.671446
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin acetylation inhibits polyubiquitin chain elongation.2015
- Author(s)
  Ohtake F, Saeki Y, Sakamoto K, Ohtake K, Nishikawa H, Tsuchiya H, Ohta T, Tanaka K, Kanno J.
- Journal Title
  
  EMBO Rep.
  
  Volume: 16 Issue: 2 Pages: 192-201
- DOI
  10.15252/embr.201439152
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26291035, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26870853, KAKENHI-PLANNED-24112004, KAKENHI-PROJECT-26000014
[Journal Article] Phosphorylated ubiquitin chain is the genuine Parkin receptor.2015
- Author(s)
  K. Okatsu, F. Koyano, M. Kimura, H. Kosako, Y. Saeki, K. Tanaka and N. Matsuda
- Journal Title
  
  The Journal of Cell Biology
  
  Volume: 209 Issue: 1 Pages: 111-128
- DOI
  10.1083/jcb.201410050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-15K19037, KAKENHI-PUBLICLY-15H01196, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-26000014
[Journal Article] A comprehensive method for detecting ubiquitinated substrates using TR-TUBE2015
- Author(s)
  Yoshida, Y., Saeki, Y., Murakami, A., Kawawaki, J., Tsuchiya, H., Yoshihara, H., Shindo, M., and Tanaka, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 112 Issue: 15 Pages: 4630-4635
- DOI
  10.1073/pnas.1422313112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26000014
[Journal Article] Structure, dynamics and functions of the proteasome2015
- Author(s)
  佐伯泰
- Journal Title
  
  生化学
  
  Volume: 87 Issue: 6 Pages: 705-722
- DOI
  10.14952/SEIKAGAKU.2015.870705
- NAID
  40020687379
- ISSN
  0037-1017
- Year and Date
  2015-12-25
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14958, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-26293018
[Journal Article] Liganded ERα stimulates the E3 ubiquitin ligase activity of UBE3C to facilitate cell proliferation2015
- Author(s)
  Okada M, Ohtake F, Nishikawa H, Wu W, Saeki Y, Takana K, Ohta T
- Journal Title
  
  Molecular Endocrinology
  
  Volume: 29 Issue: 11 Pages: 1646-1657
- DOI
  10.1210/me.2015-1125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460402, KAKENHI-PLANNED-24112005, KAKENHI-PLANNED-24112008, KAKENHI-PUBLICLY-26102741, KAKENHI-PROJECT-26670730, KAKENHI-PROJECT-26290042, KAKENHI-PROJECT-26000014
[Journal Article] Ubiquitin is phosphorylated by PINK1 to activate parkin.2014
- Author(s)
  Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., Endo, T., Fon. E. A., Trempe, J. F., Saeki, Y., Tanaka, K., and Matsuda, N.
- Journal Title
  
  Nature
  
  Volume: 510(in press) Issue: 7503 Pages: 162-166
- DOI
  10.1038/nature13392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-23570231, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657072, KAKENHI-PUBLICLY-25112522, KAKENHI-PROJECT-25870311, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-26111729, KAKENHI-PROJECT-26440070, KAKENHI-PROJECT-26440101, KAKENHI-PROJECT-26650042, KAKENHI-PROJECT-22227003
[Journal Article] Pba3-Pba4 heterodimer acts as a molecular matchmaker in proteasome α-ring formation2014
- Author(s)
  Takagi, K., Saeki, Y., Yashiroda, H., Yagi, H., Kaiho, A., Murata, S., Yamane, T., Tanaka, K., Mizushima, T. and Kato, K.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 450 Issue: 2 Pages: 1110-1114
- DOI
  10.1016/j.bbrc.2014.06.119
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24570208, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PROJECT-25870631, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26293018
[Journal Article] Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome2014
- Author(s)
  Pack, CG., Yukii, H.,　Toh-e, A., Kudo, T., Tsuchiya, H., Kaiho, A., Sakata, E., Murata, S., Sako, Y., Baumeister, W., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Nature Commun
  
  Volume: 5 Issue: 1 Pages: 3396-3396
- DOI
  10.1038/ncomms4396
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657097, KAKENHI-PROJECT-25221102, KAKENHI-PROJECT-26000014
[Journal Article] Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.2014
- Author(s)
  Takiuchi, T., Nakagawa, T., Tamiya, H., Fujita, H., Sasaki, Y., Saeki, Y., Takeda, H., Sawasaki, T., Buchberger, A., Kimura, T., and Iwai. K.
- Journal Title
  
  Genes Cells.
  
  Volume: 19 Issue: 3 Pages: 254-272
- DOI
  10.1111/gtc.12128
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24112001, KAKENHI-PLANNED-24112002, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24659136, KAKENHI-PROJECT-24790279, KAKENHI-PROJECT-25253019
[Journal Article] Ubiquitin is phosphorylated by PINK1 to activate Parkin2014
- Author(s)
  Koyano, F., Okatsu, K., Kosako, H., Tamura, Y., Go, E., Kimura, M., Kimura, Y., Tsuchiya, H., Yoshihara, H., Hirokawa, T., Endo, T., Fon, E.A., Trempe, J., Saeki, Y., Tanaka, K. and Matsuda, N.
- Journal Title
  
  Nature
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112008
[Journal Article] Structural Basis for Proteasome Formation Controlled by an Assembly Chaperone Nas22014
- Author(s)
  Satoh T, Saeki Y, Hiromoto T, Wang YH, Uekusa Y, Yagi H, Yoshihara H, Yagi-Utsumi M, Mizushima T, Tanaka K, Kato K
- Journal Title
  
  Structure
  
  Volume: (掲載確定) Issue: 5 Pages: 731-743
- DOI
  10.1016/j.str.2014.02.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J07852, KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-24112008, KAKENHI-PROJECT-24657097, KAKENHI-PROJECT-24657113, KAKENHI-PROJECT-24770102, KAKENHI-ORGANIZER-25102001, KAKENHI-PLANNED-25102008, KAKENHI-PUBLICLY-25121730, KAKENHI-PROJECT-26000014
[Journal Article] The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification2013
- Author(s)
  Tsuchiya, H., Tanaka, K., and Saeki, Y
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] The parallel reaction monitoring method contributes to highly sensitive polyubiquitin chain quantification.2013
- Author(s)
  Tsuchiya, H., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 436 Issue: 2 Pages: 223-229
- DOI
  10.1016/j.bbrc.2013.05.080
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-24657097
[Journal Article] Structural basis for specific recognition of Rpt1p, an ATPase subunit of 26 S proteasome, by proteasome-dedi-cated chaperone Hsm3p2012
- Author(s)
  Takagi, K., Kim, S., Yukii, H., Ueno, M., Morishita, R., Endo, Y., Kato, K., Tanaka, K., Saeki, Y. *, and Mizushima, T *, *Correspondences.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 12172-12182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs2012
- Author(s)
  Yoshihara, H., Fukushima T, Hakuno, F., Saeki, Y., Tanaka, K., Ito, A., Yoshida, M., Iemura, S., Natsume, T., Asano, T., Chida, K., Girnita, L., Takahashi, S
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 423 Pages: 122-127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] New crystal structure of the proteasome-dedicated chaperone Rpn14 at 1.6 A resolution. Acta. Crystallogr2012
- Author(s)
  Kim, S., Nishide, A., Saeki, Y., Takagi, K., Tanaka, K., Kato, K., Mizushima, T
- Journal Title
  
  Sect. F. Struct. Biol. Cryst. Commun
  
  Volume: 68 Pages: 517-521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] The proteasome : molecular machinery and pathophysiological roles2012
- Author(s)
  Tanaka, K., Mizushima, T., and Saeki, Y.
- Journal Title
  
  Biol Chem
  
  Volume: 393 Pages: 217-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Proteasomal degradation resolves competition between cell polarization and cellular wound healing2012
- Author(s)
  Kono, K., Saeki, Y., Yoshida, S., Tanaka, K., Pellman, D
- Journal Title
  
  Cell
  
  Volume: 150 Pages: 151-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Assembly and function of the proteasome2012
- Author(s)
  Saeki, Y and Tanaka, K.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 832 Pages: 315-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] The proteasome : molecular machinery and pathophysiological roles2012
- Author(s)
  Tanaka, K., Mizushima, T., and Saeki, Y.
- Journal Title
  
  Biol Chem
  
  Volume: 393 Pages: 217-234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657097
[Journal Article] Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy2012
- Author(s)
  Sakata, E., Bohn, S., Mihalache, O., Kiss, P., Beck, F., Nagy, I., Nickell, S., Tanaka, K., Saeki, Y., Forster, F., and Baumeister, W.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 109 Pages: 1479-1484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Hyrtioreticulins A-E, indole alkaloids inhibiting the ubiquitin-activating enzyme, from the marine sponge Hyrtios reticulatus2012
- Author(s)
  Yamanokuchi, R., Imada, K., Miyazaki, M., Kato, H., Watanabe, T., Fujimuro, M., Saeki, Y., Yoshinaga, S., Terasawa, H., Iwasaki, N., Rotinsulu, H., Losung, F., Mangindaan, R.E., Namikoshi, M., de Voogd, N.J., Yokosawa, H., Tsukamoto, S
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 20 Pages: 4437-4442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Structural basis for specific recognition of Rpt1p, an ATPase subunit of the 26S proteasome, by the proteasome-dedicated chaperone Hsm3p2012
- Author(s)
  Takagi, K., Kim, S., Yukii, H., Ueno, M., Morishita, R., Endo, Y., Kato, K., Tanaka, K., Saeki, Y., and Mizushima, Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 12172-12182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy.2012
- Author(s)
  Sakata E
- Journal Title
  
  Proc. Natl. Acad. Sci. USA.
  
  Volume: 109 Issue: 5 Pages: 1479-1484
- DOI
  10.1073/pnas.1119394109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009, KAKENHI-PROJECT-24657097
[Journal Article] Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs2012
- Author(s)
  Yoshihara H, Fukushima T, Hakuno F, Saeki Y, Tanaka K, Ito A, Yoshida M, Iemura S, Natsume T, Asano T, Chida K, Girnita L, Takahashi S-I
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 423 Issue: 1 Pages: 122-127
- DOI
  10.1016/j.bbrc.2012.05.093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22248030, KAKENHI-PROJECT-22687009, KAKENHI-PROJECT-23658222, KAKENHI-PROJECT-24380152, KAKENHI-PROJECT-24790928
[Journal Article] Proteasomal degradation resolves competition between cell polarization and cellular wound healing2012
- Author(s)
  Kono, K., Saeki, Y., Yoshida, S., Tanaka, K., and Pellman, D.
- Journal Title
  
  Cell
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Assembly and function of the proteasome2012
- Author(s)
  Saeki, Y and Tanaka, K
- Journal Title
  
  Methods Mol Biol
  
  Volume: 832 Pages: 315-337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657097
[Journal Article] Localization of the proteasomal ubiquitin receptors Rpn10 and Rpn13 by electron cryomicroscopy2012
- Author(s)
  Sakata, E., Bohn, S., Mihalache, O., Kiss, P., Beck, B., Nagy, I., Nickell, S., Tanaka, K., Saeki, Y., Forster, F., and Baumeister, W
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Pages: 1479-1484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Structural basis for specific recognition of Rpt1p, an ATPase subunit of the 26S proteasome, by a proteasome-dedicated chaperone Hsm3p2012
- Author(s)
  Takagi, T., et al
- Journal Title
  
  Journl of Biological Chemistry
  
  Volume: 287 Issue: 15 Pages: 12172-12182
- DOI
  10.1074/jbc.m112.345876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065, KAKENHI-PROJECT-24657097, KAKENHI-PROJECT-24657113
[Journal Article] Proteasomal degradation resolves competition between cell polarization and cellular wound healing2012
- Author(s)
  Kono, K., Saeki, Y., Yoshida, S., Tanaka, K., and Pellman, D.
- Journal Title
  
  Cell
  
  Volume: 150 Pages: 151-164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24657097
[Journal Article] The catalytic activity of Ubp6 enhances maturation of the proteasomal regulatory particle2011
- Author(s)
  Sakata, E., Stengel, F., Fukunaga, K., Zhou, M., Saeki, Y., Forster, F., Baumeister, W., Tanaka, K., and Robinson, CV.
- Journal Title
  
  Mol Cell
  
  Volume: 42 Pages: 637-649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] The catalytic activity of Ubp6 enhances maturation of the proteasomal regulatory particle2011
- Author(s)
  Sakata, E., Stengel, F., Fukunaga, K., Zhou, M., Saeki, Y., Forster, F., Baumeister, W., Tanaka, K., and Robinson, C.V
- Journal Title
  
  Mol Cell
  
  Volume: 42 Pages: 637-649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Sharpin is a component of the NF-κB activating linear ubiquitin chain assembly complex2011
- Author(s)
  Tokunaga, F., Nakagawa, T., Nakahara1, M., Saeki, Y., Taniguchi, M., Sakata, S., Tanaka, K., Nakano, H., and Iwai, I.
- Journal Title
  
  Nature
  
  Volume: 471 Pages: 633-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Sharpin is a component of the NF-.B activating linear ubiquitin chain assembly complex2011
- Author(s)
  Tokunaga, F., Nakagawa, T., Nakahara, M., Saeki, Y., Taniguchi, M., Sakata, S., Tanaka, K., Nakano, H., and Iwai, K
- Journal Title
  
  Nature
  
  Volume: 471 Pages: 633-636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Crystal structure of yeast Rpn14, a chaperone of the 19S regulatory particle of the proteasome2010
- Author(s)
  Kim, S. *, Saeki, Y. *, Fukunaga, K., Suzuki, A., Takagi, K., Yamane, T., Tanaka, K., Mizushima, T., and Kato, K, *Equal contribution
- Journal Title
  
  J. Biol. Chem
  
  Volume: 285 Pages: 15159-15166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Dissection of the assembly pathway of the proteasome lid in Saccharomyces cerevisiae2010
- Author(s)
  Fukunaga, K., Kudo, T., Toh-e, A., Tanaka, K., and Saeki, Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 396 Pages: 1048-1053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Polyubiquitin conjugation to NEMO by triparite motif protein 23(TRIM23) is critical in antiviral defense2010
- Author(s)
  Arimoto, K. I., Funami, K., Saeki, Y., Tanaka, K., Okawa, K., Takeuchi, O., Akira, S., Murakami, Y., and Shimotohno, K.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 15856-15861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Polyubiquitin conjugation to NEMO by tripartite motif protein 23 (TRIM23) is critical in antiviral defence2010
- Author(s)
  Arimoto, K.I., Funami, K., Saeki, Y., Tanaka, K., Okawa, K., Takeuchi, O., Akira, S., Murakami, Y., and Shimotohno, K
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 107 Pages: 15856-15861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22687009
[Journal Article] Crystal structure of yeast Rpn14, a chaperone of the 19S regulatory particles of the proteasome2010
- Author(s)
  Kim, S., Saeki, Y., Fukunaga, K., Suzuki, A., Takagi, K., Yamane, T., Tanaka, K., Mizushima, T., and Kato, K.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 15159-151566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657037
[Journal Article] Lysnie 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome2009
- Author(s)
  Saeki, Y., et al
- Journal Title
  
  The EMBO JOURNAL 28
  
  Pages: 359-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065
[Journal Article] Lysine 63-linked polyubiquitin chain may serve as a targeting signal for the 26S proteasome2009
- Author(s)
  Saeki, Y., Kudo, T., Sone, T., Kikuchi, Y., Yokosawa, H., Toh-e, A., Tanaka, K.
- Journal Title
  
  EMBO J. 18
  
  Pages: 359-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065
[Journal Article] Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle2009
- Author(s)
  Saeki, Y., Toh-E, A., Kudo, T., Kawamura, H., Tanaka, K
- Journal Title
  
  Cell
  
  Volume: vol. 137 Issue: 5 Pages: 900-913
- DOI
  10.1016/j.cell.2009.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065
[Journal Article] Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle2009
- Author(s)
  Saeki, Y., Toh-e, A., Kudo, T., Kawamura, H., Tanaka, K.
- Journal Title
  
  Cell 29
  
  Pages: 900-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065
[Journal Article] Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle.2009
- Author(s)
  Saeki, Y., et al.
- Journal Title
  
  Cell 137
  
  Pages: 900-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20370065
[Patent] ユビキチンに対する人工抗体2023
- Inventor(s)
  佐伯泰（他7名）
- Industrial Property Rights Holder
  東京都医学総合研究所、東海国立大学機構、京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Overseas
- Data Source
  KAKENHI-PLANNED-18H05498
[Patent] ユビキチンに対する人工抗体2022
- Inventor(s)
  佐伯泰、遠藤彬則、河瀬泰子、林剛介、村上裕
- Industrial Property Rights Holder
  公益財団法人東京都医学総合研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-010877
- Filing Date
  2022
- Data Source
  KAKENHI-PLANNED-18H05498
[Patent] パーキンソン病のバイオマーカーおよびその利用2014
- Inventor(s)
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Holder
  松田憲之、小谷野史香、尾勝圭、呉越、木村まゆみ、佐伯泰
- Industrial Property Rights Type
  特許
- Filing Date
  2014-02-18
- Data Source
  KAKENHI-PLANNED-24112008
[Patent] A method for determining Ubiquitin chain length2014
- Inventor(s)
  Yasushi Saeki et al
- Industrial Property Rights Holder
  Yasushi Saeki et al
- Industrial Property Rights Type
  特許
- Filing Date
  2014-11-05
- Overseas
- Data Source
  KAKENHI-PLANNED-24112008
[Patent] ポリユビキチン化基質の同定方法2013
- Inventor(s)
  吉田雪子、佐伯泰、土屋光、村上有沙、田中啓二
- Industrial Property Rights Holder
  吉田雪子、佐伯泰、土屋光、村上有沙、田中啓二
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-15
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンプロテオミクスによるPROTAC評価2024
- Author(s)
  佐伯泰
- Organizer
  京都大学オープンイノベーション機構ミニシンポジウム「創薬プロテオミクス企業とアカデミアの視点から」
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] ユビキチンプロテオミクスによるPROTAC評価2024
- Author(s)
  佐伯泰
- Organizer
  京都大学オープンイノベーション機構ミニシンポジウム「創薬プロテオミクス企業とアカデミアの視点から」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05479
[Presentation] ユビキチンプロテオミクスによるPROTAC評価2024
- Author(s)
  佐伯泰
- Organizer
  京都大学オープンイノベーション機構ミニシンポジウム「創薬プロテオミクス企業とアカデミアの視点から」
- Invited
- Data Source
  KAKENHI-WRAPUP-23H05424
[Presentation] ユビキチン創薬の最新動向とLLPS創薬の可能性2023
- Author(s)
  佐伯泰
- Organizer
  千里ライフサイエンスセミナーV1「相分離がもたらす医療・創薬の新展開」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05479
[Presentation] ストレスに応答したプロテアソーム凝縮体形成2023
- Author(s)
  佐伯泰
- Organizer
  第46回日本分子生物学会年会シンポジウム「生体分子凝縮体を介するストレスへの適応機構」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05479
[Presentation] ユビキチン創薬の最新動向とLLPS創薬の可能性2023
- Author(s)
  佐伯泰
- Organizer
  千里ライフサイエンスセミナーV1「相分離がもたらす医療・創薬の新展開」
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] プロテアソームによるタンパク質寿命決定の仕組み2023
- Author(s)
  佐伯泰
- Organizer
  第96回日本生化学会大会シンポジウム「タンパク質寿命学の創出」
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] プロテアソームによるタンパク質分解と液滴形成2023
- Author(s)
  佐伯泰
- Organizer
  第40回バイオメディシナルケミストリーシンポジウムつながり醸成企画
- Invited
- Data Source
  KAKENHI-WRAPUP-23H05424
[Presentation] プロテアソームによるタンパク質寿命決定の仕組み2023
- Author(s)
  佐伯泰
- Organizer
  学術変革領域（A）「タンパク質寿命が制御するシン・バイオロジー」キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] プロテアソームによるタンパク質寿命決定の仕組み2023
- Author(s)
  佐伯泰
- Organizer
  第96回日本生化学会大会シンポジウム「タンパク質寿命学の創出」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05479
[Presentation] プロテアソームによるタンパク質分解と液滴形成2023
- Author(s)
  佐伯泰
- Organizer
  第40回バイオメディシナルケミストリーシンポジウム「タンパク質分解」
- Invited
- Data Source
  KAKENHI-PROJECT-23H05479
[Presentation] ストレスに応答したプロテアソーム凝縮体形成2023
- Author(s)
  佐伯泰
- Organizer
  第46回日本分子生物学会年会シンポジウム「生体分子凝縮体を介するストレスへの適応機構」
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] プロテアソームによるタンパク質分解と液滴形成2023
- Author(s)
  佐伯泰
- Organizer
  第40回バイオメディシナルケミストリーシンポジウム「タンパク質分解」
- Invited
- Data Source
  KAKENHI-PLANNED-23H04921
[Presentation] ユビキチン創薬の最新動向とLLPS創薬の可能性2023
- Author(s)
  佐伯泰
- Organizer
  千里ライフサイエンスセミナーV1「相分離がもたらす医療・創薬の新展開」
- Invited
- Data Source
  KAKENHI-WRAPUP-23H05424
[Presentation] Ubiquitylation-dependent phase separation of the proteasome2022
- Author(s)
  Yasushi Saeki
- Organizer
  XI-ZOMES
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ケモテクノロジーが拓くユビキチンニューフロンティア2022
- Author(s)
  佐伯泰
- Organizer
  第16回日本ケミカルバイオロジー学会年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitylation-dependent phase separation of the proteasome2022
- Author(s)
  Yasushi Saeki
- Organizer
  Ubiquitin New Frontier "from Neo-Biology to Targeted Protein Degradation"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitylation-dependent phase separation of the proteasome2022
- Author(s)
  Yasushi Saeki
- Organizer
  XI-ZOMES
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ケモテクノロジーが拓くユビキチンニューフロンティア2022
- Author(s)
  佐伯泰
- Organizer
  日本ケミカルバイオロジー学会第16回年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 最先端プロテオミクスによって見えてきたプロテアソーム経路の基質選別メカニズム2022
- Author(s)
  佐伯泰、土屋光、遠藤彬則
- Organizer
  日本プロテオーム学会2022年大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] プロテアソーム基質の選別機構2022
- Author(s)
  佐伯泰、土屋光、林剛介、遠藤彬則
- Organizer
  第74回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 最先端プロテオミクスによって見えてきたプロテアソーム経路の基質選別メカニズム2022
- Author(s)
  佐伯泰、土屋光、遠藤彬則
- Organizer
  日本プロテオーム学会2022年大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチンコード研究の最前線～基本原理の理解と創薬～2022
- Author(s)
  佐伯泰
- Organizer
  ゲノム創薬・創発フォーラム第10回シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] プロテアソーム基質の選別機構2022
- Author(s)
  佐伯泰、土屋光、林剛介、遠藤彬則
- Organizer
  第74回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ケモユビキチン：生物学と合成化学の融合がもたらす新発想の創薬の芽2022
- Author(s)
  古畑隆史、佐伯泰、岡本晃光
- Organizer
  第1回日本科学振興協会（JAAS）キックオフミーティング
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 頑張って若さを保とう！老化とタンパク質分解2022
- Author(s)
  佐伯泰
- Organizer
  第12回CSJ化学フェスタ2022
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] 最先端プロテオミクスによって見えてきたプロテアソーム経路の基質選別メカニズム2022
- Author(s)
  佐伯泰
- Organizer
  第95回日本生化学会大会シンポジウム「ユビキチン・プロテアソーム研究のニューフロンティア」
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチンコード研究の最前線～基本原理の理解と創薬～2022
- Author(s)
  佐伯泰
- Organizer
  ゲノム創薬・創発フォーラム第10回シンポジウム「標的タンパク質分解誘導薬の可能性を探る」
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 最先端プロテオミクスによって見えてきたプロテアソーム経路の基質選別メカニズム2022
- Author(s)
  佐伯泰
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ケモユビキチン：生物学と合成化学の融合がもたらす新発想の創薬の芽2022
- Author(s)
  古畑隆史、佐伯泰、岡本晃光
- Organizer
  第1回日本科学振興協会（JAAS）キックオフミーティング
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitylation-dependent phase separation of the proteasome2022
- Author(s)
  Yasushi Saeki
- Organizer
  Ubiquitin New Frontier "from Neo-Biology to Targeted Protein Degradation"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 頑張って若さを保とう！老化とタンパク質分解2022
- Author(s)
  佐伯泰
- Organizer
  第12回CSJ化学フェスタ2022 シンポジウム「豊かな超高齢社会をつくろう～ヒトの命を支える化学～」
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチン依存的なプロテアソームの液-液相分離2021
- Author(s)
  佐伯泰、土屋光、遠藤彬則
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] ユビキチン依存的なプロテアソームの液-液相分離2021
- Author(s)
  佐伯泰、土屋光、遠藤彬則
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Understanding the ubiquitin-proteasome system by advanced proteomics2021
- Author(s)
  Yasushi Saeki、Hikaru Tsuchiya、Takuya Tomita、Akinori Endo
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] Understanding the ubiquitin-proteasome system by advanced proteomics2021
- Author(s)
  Yasushi Saeki、Hikaru Tsuchiya、Takuya Tomita、Akinori Endo
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] プロテアソーム液滴基質のプロテオーム解析2021
- Author(s)
  土屋光、佐伯泰
- Organizer
  日本プロテオーム学会2021年大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチン依存的なプロテアソームの液-液相分離2021
- Author(s)
  佐伯泰、土屋光、遠藤彬則
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] 細胞内ATPレベル低下によるユビキチン・プロテアソーム液滴の形成機構2021
- Author(s)
  遠藤彬則、田中啓二、佐伯泰
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] Understanding the ubiquitin-proteasome system by advanced proteomics2021
- Author(s)
  Yasushi Saeki、Hikaru Tsuchiya、Takuya Tomita、Akinori Endo
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] RAD23BはLLPSを駆動するユビキチンデコーダーである2020
- Author(s)
  遠藤彬則、土屋光、田中啓二、佐伯泰
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] ユビキチン研究の新展開：ケミカルバイオロジーとの融合から相分離まで2020
- Author(s)
  佐伯泰
- Organizer
  日本化学会第100春季年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] RAD23B drives polyubiquitin chain-dependent phase separation of the proteasome2020
- Author(s)
  Akinori Endo、Hikaru Tsuchiya、Keiji Tanaka, Yasushi Saeki
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ケモテクノロジーと質量分析計を活用したユビキチンコードの解読2019
- Author(s)
  佐伯泰、遠藤彬則、土屋光、大竹史明
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ユビキチン研究の新展開―相分離から分解誘導剤まで2019
- Author(s)
  佐伯泰
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] Stress- and ubiquitylation-dependent phase separation of the proteasome2019
- Author(s)
  Yasushi Saeki
- Organizer
  42nd MBSJ, Symposium ”Frontiers of in-cell protein sciences”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] Stress- and ubiquitylation-dependent phase separation of the proteasome2019
- Author(s)
  Yasushi Saeki
- Organizer
  42nd MBSJ, Symposium ”Frontiers of in-cell protein sciences”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] Stress- and ubiquitylation-dependent phase separation of the proteasome2019
- Author(s)
  Yasushi Saeki
- Organizer
  42nd MBSJ Symposium
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] 高浸透圧ストレスによるプロテアソーム液滴形成と核内タンパク質分解2019
- Author(s)
  佐伯泰
- Organizer
  第14回日本臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] 高浸透圧ストレスによるプロテアソーム液滴形成と核内タンパク質分解2019
- Author(s)
  佐伯泰
- Organizer
  第14回日本臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] MSを用いたユビキチンシグナルの網羅的解析2019
- Author(s)
  佐伯泰
- Organizer
  第11回 LC/MSワークショップ
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ユビキチン研究の新展開―相分離から分解誘導剤まで2019
- Author(s)
  佐伯泰
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ユビキチン研究の新展開―相分離から分解誘導剤まで2019
- Author(s)
  佐伯泰
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] 高浸透圧ストレスによるプロテアソーム液滴形成と核内タンパク質分解2019
- Author(s)
  佐伯泰
- Organizer
  第14回日本臨床ストレス応答学会シンポジウム
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] MSを用いたユビキチンシグナルの網羅的解析2019
- Author(s)
  佐伯泰
- Organizer
  第11回 LC/MSワークショップ
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ケモテクノロジーと質量分析計を活用したユビキチンコードの解読2019
- Author(s)
  佐伯泰、遠藤彬則、土屋光、大竹史明
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] Orbitrap Fusion Lumosを使った革新的ユビキチン研究2019
- Author(s)
  佐伯泰
- Organizer
  サーモフィッシャーサイエンティフィック質量分析フォーラム2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] ユビキチンによるタンパク質分解のしくみ：We will degrade you!2019
- Author(s)
  佐伯泰
- Organizer
  第9回CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチンによるタンパク質分解のしくみ：We will degrade you!2019
- Author(s)
  佐伯泰
- Organizer
  第9回CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] MSを用いたユビキチンシグナルの網羅的解析2019
- Author(s)
  佐伯泰
- Organizer
  第11回 LC/MSワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] Orbitrap Fusion Lumosを使った革新的ユビキチン研究2019
- Author(s)
  佐伯泰
- Organizer
  サーモフィッシャーサイエンティフィック質量分析フォーラム2019
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] ユビキチンによるタンパク質分解のしくみ：We will degrade you!2019
- Author(s)
  佐伯泰
- Organizer
  第9回CSJ化学フェスタ
- Invited
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] プロテアソーム液滴による核内タンパク質分解2019
- Author(s)
  佐伯泰
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Orbitrap Fusion Lumosを使った革新的ユビキチン研究2019
- Author(s)
  佐伯泰
- Organizer
  サーモフィッシャーサイエンティフィック質量分析フォーラム2019
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] ケモテクノロジーと質量分析計を活用したユビキチンコードの解読2019
- Author(s)
  佐伯泰、遠藤彬則、土屋光、大竹史明
- Organizer
  日本ケミカルバイオロジー学会第14回年会
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] Ub-ProT reveals global length and composition of protein ubiquitylation in cells2018
- Author(s)
  Yasushi Saeki
- Organizer
  The 8th Proteasome and Autophagy Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05681
[Presentation] Ub-ProT reveals global length and composition of protein ubiquitylation in cells.2018
- Author(s)
  Yasushi Saeki
- Organizer
  The 8th Proteasome and Autophagy Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] The Cdc48-Rad23/Dsk2 Axis Contributes to K48 Ubiquitin Chain Specificity of the Proteasome.2018
- Author(s)
  Yasushi Saeki
- Organizer
  FASEB SRC “Ubiquitin and Cellular Regulation”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitin-dependent phase separation for proteasomal degradation.2018
- Author(s)
  Yasushi Saeki
- Organizer
  Symposium on “Proteins; from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Post-translational modification code of ubiquitin in signal transduction and protein degradation2018
- Author(s)
  Fumiaki Ohtake, Yasushi Saeki, and Keiji Tanaka
- Organizer
  第91回日本生化学会シンポジウム「ユビキチン様タンパク質修飾系の多様な機能：分解だけじゃない、真核生物だけじゃない」
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitin-dependent phase separation for proteasomal degradation.2018
- Author(s)
  Yasushi Saeki
- Organizer
  International Symposium on “Proteins; from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05681
[Presentation] The Cdc48-Rad23/Dsk2 Axis Contributes to K48 Ubiquitin Chain　Specificity of the Proteasome.2018
- Author(s)
  Yasushi Saeki
- Organizer
  FASEB SRC “Ubiquitin and Cellular Regulation”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] The ubiquitin ligases ITCH and UBR5 regulate proteasomal degradation through K48/K63 branched ubiquitin chains.2018
- Author(s)
  Ohtake, F., Saeki, Y., and Tanaka, K.
- Organizer
  第41回日本分子生物学会シンポジウム「ユビキチン研究の新潮流：ユビキチンコードを識る・操る」
- Invited
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ubiquitin-dependent phase separation for proteasomal degradation.2018
- Author(s)
  Yasushi Saeki
- Organizer
  International Symposium on “Proteins; from the Cradle to the Grave”
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] p97およびRAD23によるプロテアソーム分解制御2018
- Author(s)
  佐伯泰
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PUBLICLY-17H05681
[Presentation] Ub-ProT reveals global length and composition of protein ubiquitylation in cells.2018
- Author(s)
  Yasushi Saeki
- Organizer
  The 8th Proteasome and Autophagy Congress
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] Ub-ProT reveals global length and composition of protein ubiquitylation in cells.2018
- Author(s)
  Yasushi Saeki
- Organizer
  The 8th Proteasome and Autophagy Congress.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03993
[Presentation] Post-translational modification code of ubiquitin in signal transduction and protein degradation2018
- Author(s)
  Fumiaki Ohtake, Yasushi Saeki, and Keiji Tanaka
- Organizer
  第91回日本生化学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] The ubiquitin ligases ITCH and UBR5 regulate proteasomal degradation through K48/K63 branched ubiquitin chains.2018
- Author(s)
  Ohtake, F., Saeki, Y., and Tanaka, K.
- Organizer
  第41回日本分子生物学会シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] The Cdc48-Rad23/Dsk2 Axis Contributes to K48 Ubiquitin Chain Specificity of the Proteasome.2018
- Author(s)
  Yasushi Saeki
- Organizer
  FASEB SRC “Ubiquitin and Cellular Regulation”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05681
[Presentation] The Cdc48-Rad23/Dsk2 Axis Contributes to K48 Ubiquitin Chain　Specificity of the Proteasome.2018
- Author(s)
  Yasushi Saeki
- Organizer
  FASEB SRC “Ubiquitin and Cellular Regulation”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] The NEDD4 family ubiquitin ligase ITCH regulates proteasomal degradation by seeding branched ubiquitin chains.2018
- Author(s)
  Fumiaki Ohtake, Yasushi Saeki, and Keiji Tanaka
- Organizer
  FASEB Conference ”Ubiquitin and cellular regulation”
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05498
[Presentation] The NEDD4 family ubiquitin ligase ITCH regulates proteasomal degradation by seeding branched ubiquitin chains.2018
- Author(s)
  Fumiaki Ohtake, Yasushi Saeki, and Keiji Tanaka
- Organizer
  FASEB Conference ”Ubiquitin and cellular regulation”
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497
[Presentation] p97およびRAD23によるプロテアソーム分解制御2017
- Author(s)
  佐伯泰
- Organizer
  ConBio2017
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] ユビキチン修飾の全容解明を目指して：Parallel Reaction Monitoring法によるユビキチン鎖の超高感度絶対定量法の開発と応用2016
- Author(s)
  佐伯泰、土屋光、大竹史明、田中啓二
- Organizer
  日本プロテオーム学会2016年大会
- Place of Presentation
  北里大学（東京都港区）
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] Cdc48/p97-Rad23軸がプロテアソーム分解の主要経路である2016
- Author(s)
  佐伯泰
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K14958
[Presentation] Cdc48/p97-Rad23軸がプロテアソーム分解の主要経路である2016
- Author(s)
  佐伯泰
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] Cdc48/p97-Rad23軸がプロテアソーム分解の主要経路である2016
- Author(s)
  佐伯泰
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンネットワークの全容解明を目指して2015
- Author(s)
  佐伯泰
- Organizer
  平成27年度日本生化学会関東支部例会
- Place of Presentation
  新潟日報メディアシップ（新潟県新潟市）
- Year and Date
  2015-06-20
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] The deubiquitinating enzyme, USP9X positively regulates IGF-I-dependent cell growth by inhibition of degradation of insulin receptor substrate (IRS)-2 in cancer cells2015
- Author(s)
  Haruka Furuta, Hidehito Yoshihara, Toshiaki Fukushima, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Tomoichio Asano, Kazuhiro Chida, Fumihiko Hakuno, and Shin-Ichiro Takahashi
- Organizer
  Gordon Research Conference: IGF & Insulin System in Physiology & Disease
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2015-03-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] IGFシグナルに応答して変動するユビキチン化タンパク質の網羅的解析2014
- Author(s)
  吉原英人、土屋光、吉田雪子、田中啓二、高橋伸一郎、佐伯泰
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] Elucidating the proteasome dynamics and cellular ubiquitin code2014
- Author(s)
  Yasushi Saeki
- Organizer
  The 5th International Symposium on Life Science in Toyama
- Place of Presentation
  富山大学（富山）
- Year and Date
  2014-12-11
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] ユビキチンリガーゼNedd4がIRS-2を介したIGFシグナルを増強する新しい分子機構2014
- Author(s)
  福嶋俊明、吉原英人、古田遥佳、伯野史彦、佐伯泰、中津佑介、鎌田英明、高橋伸一郎、浅野知一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] Spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome2014
- Author(s)
  Yasushi Saeki
- Organizer
  231st IMEG seminars & Minisymposium “Recent advances and future directions in high-speed AFM imaging of ATP/GTP-driven molecular machinery”
- Place of Presentation
  Kumamoto, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Novel Mechanisms by which Nedd4-IRS-2 complexes enhance IGF-I signals, and their roles in IGF-I action in prostate cancer cell proliferation2014
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Fumihiko Hakuno, Yasushi Saeki, Yusuke Nakatsu, Hideaki Kamata, Tomoichiro Asano, and Shin-Ichiro Takahashi
- Organizer
  7th International Congress of the GRS and IGF Society
- Place of Presentation
  Singapore
- Year and Date
  2014-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] The deubiquitinating enzyme, USP9X positively regulates insulin-like growth factor (IGF)-dependent cell growth by inhibition of degradation of IGF-I receptor (IGF-IR) and insulin receptor substrate (IRS)-2 in cancer cells2014
- Author(s)
  Haruka Furuta, Hidehito Yoshihara, Toshiaki Fukushima, Yasushi Saeki, Akihiro Ito, Claire Worrall, Leonard Girnita, Keiji Tanaka, Minoru Yoshida, Tomoichio Asano, Kazuhiro Chida, Fumihiko Hakuno, and Shin-Ichiro Takahashi
- Organizer
  7th International Congress of the GRS and IGF Society
- Place of Presentation
  Singapore
- Year and Date
  2014-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] A comprehensive analysis of ubiquitin linkages and length specificities of ubiquitin-binding proteins2014
- Author(s)
  Yasushi Saeki
- Organizer
  1st　International Meeting for New Aspects of the Ubiquitin Research
- Place of Presentation
  国際高等研究所レクチャーホール（京都）
- Year and Date
  2014-11-10
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] 細胞内タンパク質分解装置プロテアソーム研究の最前線2014
- Author(s)
  佐伯泰
- Organizer
  金沢大学バイオAFM先端研究センターセミナー
- Place of Presentation
  金沢
- Year and Date
  2014-01-08
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] プロテアソームの分子集合と動態に関する研究2014
- Author(s)
  佐伯　泰
- Organizer
  日本生化学会平成26年度奨励賞受賞講演
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-15
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] Elucidating the proteasome dynamics and cellular ubiquitin code2014
- Author(s)
  Yasushi Saeki
- Organizer
  The 5th International Symposium on Life Science in Toyama
- Place of Presentation
  富山大学（富山）
- Year and Date
  2014-12-11
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] Absolute quantification of ubiquitin-linkages and ubiquitin-binding proteins by parallel reaction monitoring from biological complex samples2013
- Author(s)
  Yasushi Saeki
- Organizer
  HUPO2013
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンコード解析法とプロテアソーム研究の最前線2013
- Author(s)
  佐伯泰
- Organizer
  東京工業大学フロンティア研究機構セミナー
- Place of Presentation
  横浜
- Year and Date
  2013-08-30
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Ub-ProT: A novel method to determine the chain length of the polyubiquitylated proteins.2013
- Author(s)
  Yasushi Saeki, Hikaru Tsuchiya, Ai Kaiho, and Keiji Tanaka
- Organizer
  4th IGAKUKEN International Symposium on“Cutting-edge of the Ubiquitin Proteasome System”
- Place of Presentation
  Tokyo, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] プロテアソームダイナミクス2013
- Author(s)
  佐伯泰
- Organizer
  理化学研究所シンポジウム「プロテアソームダイナミクスの理解を目指して」
- Place of Presentation
  東京
- Year and Date
  2013-01-17
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 質量分析計を用いたユビキチン修飾の解析2013
- Author(s)
  佐伯　泰
- Organizer
  新学術領域研究「ユビキチンネオバイオロジー：拡大するタンパク質制御システム」第1回班会議
- Place of Presentation
  淡路
- Year and Date
  2013-01-29
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] A deubiquitinating enzyme, USP7, is associated with insulin receptor substrate (IRS)-2 forming a negative feedback loop in insulin/IGF signaling2013
- Author(s)
  Hidehito Yoshihara, Toshikai Fukushima, Furuta Haruka, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Shunichiro Iemura, Tohru Natsume, Shin-Ichiro Takahashi
- Organizer
  EMBO Conference"Ubiquitin and ubiquitin-like proteins : from structure to function
- Place of Presentation
  Riva del Garda, Italy
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] プロテアソームダイナミクス2013
- Author(s)
  佐伯泰
- Organizer
  理化学研究所シンポジウム「プロテアソームダイナミクスの理解を目指して」
- Place of Presentation
  東京
- Year and Date
  2013-01-17
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Quantitative Live-Cell Imaging Reveals Spatio-Temporal Dynamics and Cytoplasmic Assembly of the 26S Proteasome2013
- Author(s)
  Yasushi Saeki, Chan-Gi Pack,1 Haruka Yukii, and Keiji Tanaka
- Organizer
  EMBO Conference on Ubiquitin and ubiquitin-like proteins “From structure to function”
- Place of Presentation
  Riva der Garda, Italy
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] A method to determine the chain length of the polyubiqutinated proteins2013
- Author(s)
  Hikaru Tsuchia, Keiji Tanaka, and Yasushi Saeki
- Organizer
  EMBO Conference on Ubiquitin and ubiquitin-like proteins “From structure to function”
- Place of Presentation
  Riva der Garda, Italy
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンコード解析法の開発2013
- Author(s)
  佐伯　泰、土屋　光、田中啓二
- Organizer
  第86回日本生化学会大会シンポジウム
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンコード解析法とプロテアソーム研究の最前線2013
- Author(s)
  佐伯　泰
- Organizer
  東京工業大学フロンティア研究機構セミナー
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチンコード解析法の開発2013
- Author(s)
  佐伯泰、土屋光、田中啓二
- Organizer
  酵母遺伝学フォーラム第46回研究報告会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] The formation mechanism of the proteasome granules2013
- Author(s)
  Yasushi Saeki, Haruka Yukii, Naoko Arai, Ai Kaiho, and Keiji Tanaka
- Organizer
  The 35^<th> Natio Conference"The Ubiquitin-Proteasome System : From Basic Mechanisms to Pathophysiological Roles"
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 細胞内ポリユビキチン化タンパク質の鎖長制御機構2013
- Author(s)
  佐伯　泰、土屋　光、吉原英人、田中啓二
- Organizer
  第36回日本分子生物学会年会ワークショップ
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] プロテアソームは細胞内ATPレベルの低下を感知して顆粒を形成する2013
- Author(s)
  佐伯　泰、雪井　悠、田中啓二
- Organizer
  第65回日本細胞生物学会大会シンポジウム
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] The formation mechanism of the proteasome granules2013
- Author(s)
  Yasushi Saeki, Haruka Yukii, Naoko Arai, Ai Kaiho, and Keiji Tanaka
- Organizer
  The 35th Natio Conference “The Ubiquitin-Proteasome System: From Basic Mechanisms to Pathophysiological Roles”
- Place of Presentation
  Sapporo, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] A method to determine the chain length of the polyubiqutinated proteins2013
- Author(s)
  Hikaru Tscuchiya, Yasushi Saeki, Ai Kaiho, Keiji Tanaka, and Tetsu Akiyama
- Organizer
  The 35th Natio Conference “The Ubiquitin-Proteasome System: From Basic Mechanisms to Pathophysiological Roles”
- Place of Presentation
  Sapporo, Japan
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] Quantitative Live-Cell Imaging Reveals Spatio- Temporal Dynamics and Cytoplasmic Assembly of the 26S Proteasome2013
- Author(s)
  Yasushi Saeki, Chan-Gi Pack,1 Haruka Yukii, and Keiji Tanaka
- Organizer
  EMBO Conference on Ubiquitin and ubiquitin-like proteins"From structure to function"
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] A deubiquitinating enzyme, USP7, is associated with insulin receptor substrate (IRS)-2 forming a negative feedback loop in insulin/IGF signaling2013
- Author(s)
  Hidehito Yoshihara, Toshikai Fukushima, Furuta Haruka, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Shunichiro Iemura, Tohru Natsume, Takahashi Shin-Ichiro
- Organizer
  EMBO Conference “Ubiquitin and ubiquitin-like proteins: from structure to function
- Place of Presentation
  Riva del Garda, Italy
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] プロテアソームは細胞内ATPレベルの低下を感知して顆粒を形成する2013
- Author(s)
  佐伯泰,雪井悠,田中啓二
- Organizer
  第65回日本細胞生物学会大会シンポジウム「細胞の中の生々流転—「もの」の動態に基づく機能制御」
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Regulation by ubiquitin proteasome system2012
- Author(s)
  Yasushi Saeki
- Organizer
  Core-to-Core Project sponsored by JSPS International Seminar, New Insights into the Molecular Basis of Prevention of Diseases in the Aging Society Caused by Modulation of Insulin-Like Activities
- Place of Presentation
  東京
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Ubiquitin ligase Nedd4 interacts with insulin receptor substrate (IRS)-2 in response to humoral/nutritional stimuli, thereby enhancing IRS-2-mediated IGF/insulin signals through a novel mechanism2012
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Kazuhiro Chida, Hideyuki Sakoda, Tomoichiro Asano, and Shin-Ichiro Takahashi
- Organizer
  The 6th Interntional Congress of the GRS-IGF Society
- Place of Presentation
  Munich, Germany
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] Structure and dynamics of the 26S proteasome2012
- Author(s)
  Yasushi Saeki
- Organizer
  熊本大学発生医学研究所リエゾンラボ研究会
- Place of Presentation
  熊本
- Year and Date
  2012-12-19
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 細胞内タンパク質分解装置プロテアソームの分子集合と作動機構2012
- Author(s)
  佐伯泰,坂田絵理,白燦基,佐甲靖志, W. Baumeister,田中啓二
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 新規ユビキチン鎖長決定法の開発2012
- Author(s)
  土屋光、海保愛、田中啓二、佐伯泰
- Organizer
  第35回分子生物学会ワークショップ
- Place of Presentation
  博多
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 細胞内タンパク質分解装置プロテアソームの分子集合と作動機構2012
- Author(s)
  佐伯泰, 坂田絵理, 白燦基、佐甲靖志, W. Baumeister,田中啓二
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Regulation by ubiquitin-proteasome system.2012
- Author(s)
  Yasushi Saeki
- Organizer
  Core-to-Core Project sponsored by JSPS International Seminar,
- Place of Presentation
  東京
- Year and Date
  2012-08-25
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] 出芽酵母の休止期において形成されるプロテアソームストレージ顆粒の解析2012
- Author(s)
  雪井悠、新井直子、田中啓二、佐伯泰
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 出芽酵母の休止期において形成されるプロテアソームストレージ顆粒の解析2012
- Author(s)
  雪井悠,新井直子,田中啓二,佐伯泰
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 出芽酵母の休止期において形成されるプロテアソーム顆粒の解析2012
- Author(s)
  雪井悠,新井直子,田中啓二,佐伯泰
- Organizer
  第35回分子生物学会
- Place of Presentation
  博多
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] プロテアソーム可塑性 : 分子集合から顆粒形成まで2012
- Author(s)
  佐伯泰,雪井悠,土屋光,田中啓二
- Organizer
  第85回日本生化学会大会シンポジウム
- Place of Presentation
  博多
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] プロテアソーム可塑性:分子集合から顆粒形成まで2012
- Author(s)
  佐伯泰、雪井悠、土屋光、田中啓二
- Organizer
  第85回日本生化学会大会シンポジウム
- Place of Presentation
  博多
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 選択的なポリユビキチン鎖の検出・定量法の開発2012
- Author(s)
  佐伯泰
- Organizer
  平成24年度文部科学省新学術領域研究「ユビキチンネオバイオロジー:拡大するタンパク質制御システム」kick-off シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-09-26
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 選択的なポリユビキチン鎖の検出・定量法の開発2012
- Author(s)
  佐伯　泰
- Organizer
  新学術領域研究「ユビキチンネオバイオロジー：拡大するタンパク質制御システム」kick-off シンポジウム
- Place of Presentation
  京都
- Year and Date
  2012-09-26
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] 細胞内タンパク質分解装置プロテアソームの分子集合と作動機構2012
- Author(s)
  佐伯泰,坂田絵理,雪井悠,水島恒祐, W. Baumeister,田中啓二
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Structure and dynamics of the 26S proteasome2012
- Author(s)
  Yasushi Saeki
- Organizer
  熊本大学発生医学研究所リエゾンラボ研究会
- Place of Presentation
  熊本
- Year and Date
  2012-12-19
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] 新規ユビキチン鎖長決定法の開発2012
- Author(s)
  土屋光、海保愛、田中啓二、佐伯泰
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 出芽酵母の休止期において形成されるプロテアソーム顆粒の解析2012
- Author(s)
  雪井悠、新井直子、田中啓二、佐伯泰
- Organizer
  第35回分子生物学会
- Place of Presentation
  博多
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Structure and dynamics of the 26S proteasome2012
- Author(s)
  Yasushi Saeki
- Organizer
  熊本大学発生医学研究所リエゾンラボ研究会
- Place of Presentation
  熊本
- Year and Date
  2012-12-19
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 出芽酵母26Sプロテアソームは細胞質で完成する2012
- Author(s)
  佐伯泰、白燦基、東江昭夫、田中啓二
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation]2011
- Author(s)
  佐伯泰
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] Assembly, structure, and function of the 26S proteasome.2011
- Author(s)
  Yasushi Saeki
- Organizer
  Korea-Japan Symposium on Protein Metabolism
- Place of Presentation
  Seoul, Korea(招待講演)
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] Assembly, structure, and function of the 26S proteasome.2011
- Author(s)
  Yasushi Saeki
- Organizer
  Korea-Japan Symposium on Protein Metabolism
- Place of Presentation
  Seoul, Korea(招待講演)
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] The 26S proteasome completes its assembly process in the cytoplasm prior to the nuclear translocation2011
- Author(s)
  Haruka Yukii, Yasushi Saeki, Changi Pack, Keisuke Fukunaga, Eri Sakata, Yasushi Sako, Akio Toh-e, Wolfgang Baumeister, Keiji Tanaka
- Organizer
  EMBO Conference, Ubiquitin and ubiquitin-like modifiers
- Place of Presentation
  Cavtat, Croatia
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 出芽酵母26Sプロテアソームは細胞質で完成する2011
- Author(s)
  佐伯泰、白燦基、東江昭夫、田中啓二
- Organizer
  酵母遺伝学フォーラム第44回研究報告会
- Place of Presentation
  博多
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 出芽酵母26Sプロテアソームは細胞質で完成する2011
- Author(s)
  佐伯泰、白燦基、東江昭夫、田中啓二
- Organizer
  第44回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Ubiquitin ligase Nedd4 recruits insulin receptor substrate (IRS)-2 to membrane fractions, enhancing IRS-2-mediated signals followed by mitogenic bioactivity of insulin-like growth factors (IGFs)2011
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Kazuhiro Chida, Tomoichiro Asano, Shin-Ichiro Takahashi
- Organizer
  Gordon Research Conference"Insulin-like Growth Factors in Physiology & Disease"
- Place of Presentation
  Ventura CA, USA
- Year and Date
  2011-05-01
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] Wolfgang Baumeister, Keiji Tanaka:Ubp6 and Rad23 are involved in the 26S proteasome assembly2011
- Author(s)
  Keisuke Fukunaga, Eri Sakata, Florian Stengel, Yasushi Saeki, Carol V. Robinson
- Organizer
  第44回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Assembly, structure, and function of the 26S proteasome2011
- Author(s)
  Yasushi Saeki
- Organizer
  Korea-Japan Symposium on Protein Metabolism
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 26Sプロテアソームの分子集合機構2011
- Author(s)
  佐伯泰,福永圭佑,工藤泰,川村ひとみ,田中啓二
- Organizer
  平成22年度ターゲットタンパク研究プログラム成果発表会
- Place of Presentation
  東京
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation]2011
- Author(s)
  佐伯泰
- Organizer
  東京大学大学院農学生命科学科第7回応用動物科学セミナー「プロテアソーム研究の最前線」
- Place of Presentation
  東京
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Assembly, structure, and function of the 26S proteasome.2011
- Author(s)
  Saeki Yasushi
- Organizer
  Korea-Japan Symposium on Protein Metabolism
- Place of Presentation
  Seoul/Korea
- Year and Date
  2011-01-28
- Data Source
  KAKENHI-PUBLICLY-21025038
[Presentation] 出芽酵母26Sプロテアソームは細胞質で完成する2011
- Author(s)
  佐伯泰、白燦基、東江昭夫、田中啓二
- Organizer
  酵母遺伝学フォーラム第44回研究報告会
- Place of Presentation
  博多
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Ubp6 and Rad23 are involved in the 26S proteasome assembly2011
- Author(s)
  Keisuke Fukunaga, Eri Sakata, Florian Stengel, Yasushi Saeki, Carol V. Robinson, Wolfgang Baumeister, Keiji Tanaka
- Organizer
  EMBO Conference, Ubiquitin and ubiquitin-like modifiers
- Place of Presentation
  Cavtat, Croatia
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 26Sプロテアソームの分子集合と作動原理2011
- Author(s)
  佐伯泰
- Organizer
  第19回酵母合同シンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] Rad23とUbp6は26Sプロテアソームの分子集合に関与する2011
- Author(s)
  佐伯泰
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Rad23とUbp6は26Sプロテアソームの分子集合に関与する2011
- Author(s)
  佐伯泰、福永圭佑、坂田絵里、Florian Stengel、Carol V. Robinson、Wolfgang Baumeister、田中啓二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] プロテアソーム研究の最前線2011
- Author(s)
  佐伯泰
- Organizer
  バイオコンファレンス2011首都大学東京
- Place of Presentation
  東京
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 出芽酵母26Sプロテアソームは細胞質で完成する2011
- Author(s)
  佐伯泰、白燦基、東江昭夫、田中啓二
- Organizer
  第44回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 巨大で複雑なタンパク分解装置の動態と作動機構.細胞内タンパク質分解装置の構造と活性調節機構2011
- Author(s)
  佐伯泰, 西尾和也, 坂田絵理, 福永圭佑, 雪井悠, W. Baumeister, 森本幸生, 田中啓二
- Organizer
  平成23年度ターゲットタンパク研究プログラム成果発表会
- Place of Presentation
  東京
- Year and Date
  2011-12-27
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Rad23とUbp6は26Sプロテアソームの分子集合に関与する2011
- Author(s)
  佐伯泰、福永圭佑、坂田絵里、Florian Stengel、Carol V. Robinson、Wolfgang Baumeister、田中啓二
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 肝細胞においてNedd4はインスリン受容体基質(IRS)-2のユビキチン化を介してインスリンシグナルを増強する2011
- Author(s)
  福嶋俊明,吉原英人,伯野史彦,佐伯泰,田中啓二,伊藤昭博,中津祐介,鎌田英明,高橋伸一郎,浅野知一郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(口頭発表、ポスター発表)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] 26Sプロテアソームの分子集合と作動原理2011
- Author(s)
  佐伯泰
- Organizer
  第19回酵母合同シンポジウム
- Place of Presentation
  東京(招待講演)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Assembly, structure, and function of the 26S proteasome2011
- Author(s)
  Yasushi Saeki
- Organizer
  Korea-Japan Symposium on Protein Metabolism
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 26Sプロテアソームの分子集合機構2011
- Author(s)
  佐伯泰, 福永圭佑, 工藤泰, 川村ひとみ, 田中啓二
- Organizer
  平成22年度ターゲットタンパク研究プログラム成果発表会
- Place of Presentation
  東京
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 東京大学大学院農学生命科学科2011
- Author(s)
  佐伯泰
- Organizer
  第7回応用動物科学セミナー「プロテアソーム研究の最前線」
- Place of Presentation
  東京
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] Ubp6はプロテアソームの分子集合を正に制御する2011
- Author(s)
  福永圭佑、坂田絵里、佐伯泰、田中啓二
- Organizer
  酵母遺伝学フォーラム第44回研究報告会
- Place of Presentation
  博多
- Year and Date
  2011-09-07
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] The 26S proteasome completes its assembly process in the cytoplasm prior to the nuclear translocation2011
- Author(s)
  Haruka Yukii, Yasushi Saeki, Changi Pack, Keisuke Fukunaga, Eri Sakata, Yasushi Sako, Akio Toh-e, Wolfgang Baumeister, Keiji Tanaka
- Organizer
  EMBO Conference, Ubiquitin and ubiquitin-like modifiers
- Place of Presentation
  Cavtat, Croatia
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 26Sプロテアソームはどこで完成するか2010
- Author(s)
  佐伯泰,白燦基,川村ひとみ,東江昭夫,佐甲靖志,田中啓二
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] プロテアソーム19S制御因子複合体の分子集合機構2010
- Author(s)
  佐伯泰, 福永圭佑, 田中啓二
- Organizer
  平成22年度ターゲットタンパク研究プログラム成果発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] A quantitative proteomic analysis of tUb-binding proteins with different length in yeast2010
- Author(s)
  Keisuke Fukunaga, Yasushi Saeki, and Keiji Tanaka
- Organizer
  1st conference on PPDUP
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Assembly pathway of the 19S proteasome lid in yeast2010
- Author(s)
  福永圭佑, 工藤泰, 東江昭夫, 田中啓二, 佐伯泰
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] A proteomic analysis of ubiquitin-binding proteins by unclavable polyubiquitins in yeast2010
- Author(s)
  工藤泰, 福永圭祐, 田中啓二, 佐伯泰
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 26Sプロテアソームはどこで完成するか?2010
- Author(s)
  佐伯泰
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PUBLICLY-21025038
[Presentation] 26Sプロテアソームの分子集合と作動原理2010
- Author(s)
  佐伯泰
- Organizer
  第19回酵母合同シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] プロテアソーム19S制御因子複合体の分子集合機構2010
- Author(s)
  佐伯泰,福永圭佑,田中啓二
- Organizer
  平成22年度ターゲットタンパク研究プログラム成果発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 26Sプロテアソームはどこで完成するか?2010
- Author(s)
  佐伯泰, 白燦基, 川村ひとみ, 東江昭夫, 佐甲靖志, 田中啓二
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] 26Sプロテアソームはどこで完成するか?2010
- Author(s)
  佐伯泰, 白燦基, 川村ひとみ, 東江昭夫, 佐甲靖志, 田中啓二
- Organizer
  BMB2010(第33回分子生物学会、第83回日本生化学会合同年会)
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22657037
[Presentation] 26Sプロテアソームの分子集合と作動原理2010
- Author(s)
  佐伯泰
- Organizer
  第19回酵母合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Single particle analysis of the 26S proteasome by high-resolution electron cryo-microscopy and advanced image analysis2010
- Author(s)
  Okuma, Y., Kasuya, D., Mitsuoka, K., Saeki, Y., Yasunaga, T.
- Organizer
  日本生物物理学会第48回年会
- Place of Presentation
  東北大学・川内北キャンパス
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-20370065
[Presentation] 26Sプロテアソームの分子集合と作動原理2010
- Author(s)
  佐伯泰
- Organizer
  第19回酵母合同シンポジウム
- Place of Presentation
  東京
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PUBLICLY-21025038
[Presentation] 出芽酵母19Sプロテアソーム制御因子Lid複合体の分子集合2010
- Author(s)
  福永圭佑, 工藤泰, 東江昭夫, 田中啓二, 佐伯泰
- Organizer
  酵母遺伝学フォーラム第43回研究報告会
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] Structure and dynamics of the 26S proteasome.
- Author(s)
  Yasushi Saeki
- Organizer
  熊本大学発生医学研究所リエゾンラボ研究会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] プロテアソームダイナミクス
- Author(s)
  佐伯　泰
- Organizer
  理化学研究所シンポジウム「プロテアソームダイナミクスの理解を目指して」
- Place of Presentation
  和光
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] Nedd4-IRS2複合体の形成機構と複合体ががん細胞の過増殖誘導に果たす役割
- Author(s)
  福嶋俊明、吉原英人、古田遥佳、伯野史彦、千田和広、佐伯泰、田中啓二、伊藤昭博、吉田稔、中津佑介、鎌田英明、高橋伸一郎、浅野知一郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03 – 2013-12-06
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] Molecular mechanisms by which ubiquitin ligase Nedd4 enhances IRS-2-mediated IGF signaling
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Fumihiko Hakuno, Yasushi Saeki, Yusuke Nakatsu, Hideaki Kamata, Shin-Ichiro Takahashi, Tomoichiro Asano
- Organizer
  Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  神戸ポートアイランド, 神戸
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26460369
[Presentation] プロテアソーム可塑性：分子集合から顆粒形成まで
- Author(s)
  佐伯　泰、雪井　悠、土屋　光、田中啓二
- Organizer
  第85回日本生化学会大会シンポジウム
- Place of Presentation
  博多
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 出芽酵母の休止期において形成されるプロテアソーム顆粒の解析
- Author(s)
  雪井悠、新井直子、田中啓二、佐伯　泰
- Organizer
  第35回分子生物学会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] 出芽酵母の休止期において形成されるプロテアソームストレージ顆粒の解析
- Author(s)
  雪井悠、新井直子、田中啓二、佐伯泰
- Organizer
  酵母遺伝学フォーラム第45回研究報告会
- Place of Presentation
  宇治
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] The deubiquitinating enzyme, USP9X positively regulates insulin-like growth factor (IGF)-dependent cell growth by inhibition of degradation of IGF-I receptor (IGF-IR) and insulin receptor substrate (IRS)-2 in cancer cells
- Author(s)
  Haruka Furuta, Hidehito Yoshihara, Toshiaki Fukushima, Yasushi Saeki, Akihiro Ito, Claire Worrall, Leonard Girnita, Keiji Tanaka, Minoru Yoshida, Tomoichio Asano, Kazuhiro Chida, Fumihiko Hakuno, Shin-Ichiro Takahashi
- Organizer
  The International Congress of the GRS and the IGF Society
- Place of Presentation
  Suntec Convention & Exhibition Centre, Suntec City, Singapore
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460369
[Presentation] Regulation by ubiquitin-proteasome system
- Author(s)
  Yasushi Saeki
- Organizer
  Core-to-Core Project sponsored by JSPS International Seminar,
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] The deubiquitinating enzyme, USP9X positively regulates IGF-I-dependent cell growth by inhibition of degradation of insulin receptor substrate (IRS)-2 in cancer cells
- Author(s)
  Haruka Furuta, Hidehito Yoshihara, Toshiaki Fukushima, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Tomoichio Asano, Kazuhiro Chida, Fumihiko Hakuno, Shin-Ichiro Takahashi
- Organizer
  Gordon Research Conference: IGF and Insulin System in Physiology and disease
- Place of Presentation
  Ventura Beach Marriott, Ventura, USA
- Year and Date
  2015-03-08 – 2015-03-13
- Data Source
  KAKENHI-PROJECT-26460369
[Presentation] タンパク質分解装置プロテアソームの細胞内動態
- Author(s)
  佐伯　泰
- Organizer
  第21回酵母合同シンポジウム
- Place of Presentation
  東京大学（東京）
- Year and Date
  2014-09-03 – 2014-09-04
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] ユビキチンコードの全容解明を目指して
- Author(s)
  佐伯　泰
- Organizer
  日本農芸化学会2015大会シンポジウム
- Place of Presentation
  岡山大学（岡山）
- Year and Date
  2015-03-26 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PLANNED-24112008
[Presentation] ユビキチン結合ドメインタンパク質によるユビキチンシグナルの発動メカニズム
- Author(s)
  吉原英人、海保愛、新井直子、土屋光、高橋伸一郎、田中啓二、佐伯泰
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2013-09-11 – 2013-09-13
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] 細胞内タンパク質分解装置プロテアソームの分子集合と作動機構
- Author(s)
  佐伯　泰
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-22687009
[Presentation] A deubiquitinating enzyme, USP7, is associated with insulin receptor substrate (IRS)-2 forming a negative feedback loop in insulin/IGF signaling
- Author(s)
  Hidehito Yoshihara, Toshiaki Fukushima, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Shunichiro Iemura, Tohru Natsume, Tomoichiro Asano, Kazuhiro Chida, Leonard Girnita, and Shin-Ichiro Takahashi
- Organizer
  The 6th Interntional Congress of the GRS-IGF Society
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-22248030
[Presentation] がん細胞では、脱ユビキチン化酵素USP9XによりIGF-I受容体およびIRS-2の分解が抑制され、IGF依存性増殖が亢進している
- Author(s)
  古田遥佳、吉原英人、福嶋俊明、佐伯泰、田中啓二、伊藤昭博、吉田稔、浅野知一郎、千田和広、伯野史彦、高橋伸一郎
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-03 – 2013-12-06
- Data Source
  KAKENHI-PROJECT-25221204
[Presentation] Novel Mechanisms by which Nedd4-IRS-2 Complexes Enhance IGF-I signals, and their Roles in IGF-I Action in Prostate Cancer Cell Proliferation
- Author(s)
  Toshiaki Fukushima, Hidehito Yoshihara, Haruka Furuta, Fumihiko Hakuno, Yasushi Saeki, Yusuke Nakatsu, Hideaki Kamata, Tomoichiro Asano, and Shin-Ichiro Takahashi
- Organizer
  The International Congress of the GRS and the IGF Society
- Place of Presentation
  Suntec Convention & Exhibition Centre, Suntec City, Singapore
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26460369
[Presentation] プロテアソームの細胞内動態
- Author(s)
  佐伯　泰
- Organizer
  第19回日本病態プロテアーゼ学会学術集会シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター（大阪）
- Year and Date
  2014-08-08 – 2014-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-26293018
[Presentation] 細胞内タンパク質分解装置プロテアソームの分子集合と作動機構
- Author(s)
  佐伯　泰
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-24657097
[Presentation] A deubiquitinating enzyme, USP7, is associated with insulin receptor substrate (IRS)-2 forming a negative feedback llop in insulin/IGF signaling
- Author(s)
  Hidehito Yoshihara, Toshikai Fukushima, Furuta Haruka, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Shunichiro Iemura, Tohru Natsume, Takahashi Shin-Ichiro
- Organizer
  EMBO Conference
- Place of Presentation
  Riva del Garda, Italy
- Year and Date
  2013-10-01 – 2013-10-05
- Data Source
  KAKENHI-PROJECT-25221204

1. ITO Akihiro (40391859)

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# of Collaborated Products: 17 results
2. TAKAHASHI Shin-Ichiro (00197146)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. HAKUNO Fumihiko (30282700)

# of Collaborated Projects: 3 results

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5. IWAI Kazuhiro (60252459)

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24. Chida Kazuhiro

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26. Yamanaka Daisuke

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27. Asano Tomoichiro

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28. Takenaka Asako

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29. KAIHO Ai

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32. Torres-Aleman Ignacio

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33. Duan Cunming

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34. Weghuber Julian

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35. Belfiore Antonino

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36. O'Connor Rosemary

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37. Forbes Briony

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38. WU Wenwen

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39. ARIYOSI Mariko

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40. SATO Ken

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41. MATSUDA Noriyuki

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42. SYODA Takuji

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65. 石戸聡

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67. 田中元雅

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68. 末武勲

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saeki yasushi 佐伯 泰

SAEKI Yasushi 佐伯 泰

Research Projects

Research Products

Co-Researchers

プロテアソームとユビキチンコードの統合的解析Principal Investigator

Principal Investigator

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Principal Investigator

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Mechanism of how the proteasome determines protein lifetimePrincipal Investigator

Principal Investigator

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Integrated understanding of proteasomal degradation and the ubiquitin codePrincipal Investigator

Principal Investigator

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New Frontier for Ubiquitin Biology Driven by Chemo-technologiesPrincipal Investigator

Principal Investigator

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New frontier for ubiquitin biology driven by chemo-technologiesArea Organizer

Area Organizer

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New frontier for ubiquitin biology driven by chemo-technologiesPrincipal Investigator

Principal Investigator

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Decryption of the ubiquitin code by chemo-technologies and advanced proteomicsPrincipal Investigator

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Elucidation of protein networks controlling proteasomal degradationPrincipal Investigator

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Elucidation of degradation signals presented on aberrant nascent polypeptidesPrincipal Investigator

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Elucidation of the mechanism for nuclear export of the proteasomePrincipal Investigator

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Formation mechanism and physiological significance of proteasome specklePrincipal Investigator

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saeki yasushi 佐伯泰

SAEKI Yasushi 佐伯泰

[Book] 実験医学別冊『決定版質量分析活用スタンダード』2023

[Book] 実験医学別冊『決定版質量分析活用スタンダード』2023