SUDA TATSUO 須田立雄

… Alternative Names

須田立雄スダタツオ

SUDA Tatsuo 須田立雄

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Researcher Number	90014034
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Affiliation (based on the past Project Information) *help	2015 – 2016: 埼玉医科大学, 医学部, 客員教授 2015: 埼玉医科大, 医学部, 客員教授 2013: 埼玉医科大学, 医学部, 客員教授 2006: 埼玉医科大学, 医学部, 客員教授 2002 – 2005: 埼玉医科大学, 医学部, 教授 … More 1987 – 1999: School of Dentistry, Showa University, 歯学部, 教授 1991: 昭和大学, 歯科部, 教授 1989: Showa Univ., Sch. Dentistry Professor, 歯学会, 教授 1989: 昭和大学, 歯学部・生化学教室, 教授 1986: 昭和大, 歯学部, 教授 1986: 昭和大学, 歯学部生化学教室, 教授 1985: 昭和大学, 歯, 教授 Less
Review Section/Research Field	Principal Investigator Functional basic dentistry / Orthopaedic surgery Except Principal Investigator Functional basic dentistry / Morphological basic dentistry / Orthopaedic surgery / Surgical dentistry / Functional basic dentistry / Hematology / Pathological medical chemistry
Keywords	Principal Investigator 破骨細胞 / 活性型ビタミンD / 骨吸収 / 骨芽細胞 / ODF / bone resorption / M-CSF / OCIF / カルシトニン / osteoclast … More / 副甲状腺ホルモン / エストロゲン / カルシウム / 細胞融合 / マクロファージ / osteoblasts / RANK / IL-7 / Smad / インターロイキン-7 / hemopoiesis / osteoporosis / estrogen / アンドロゲン / Bリンパ球 / 骨髄造血 / 骨粗鬆症 / bisphosphonates / 波状縁 / gp130 / osteoblast / ビタミンD / インターロイキン6 / 腎臓 / 1alpha, 25-Dihydroxyvitamin D_3 / マクロファ-ジ / ポリアミン / カルシウム吸収 / 1alpha, 25(OH)_2D_3 / Osteoclast / マクロファ-ジコロニ-刺激因子 / 骨吸収因子 / 発癌プロモーション / マクロファージの融合 / Transglutaminase / Spermidine / Calcium / Cell Fusion / Macrophage / トランスグルタミナ-ゼ / スペルミジン / macrophage fusion factor (MFF) / differentiation-inducing factor (DIF) / 1alpha,25-dihydroxyvitamin D_3 [1alpha,25(OH)_2D_3 / コロニー形成因子(CSF) / 骨髄細胞 / マクロファージ融合因子(MFF) / マクロファージ融合因子 / 活性型ビタミンD_3(1α,25(OH)_2D_3) / 分化誘導因子(DIF) / Cell-fusion / Macrophages / Vitamin D / 多核巨細胞 / 骨吸収活性 / MGBG / LPS / DIF / OAF / トリグリセライド / 融合 / 肺胞マクロファージ / 分化誘導因子 / calcium regulatory hormones / transcriptional control / microarray / osteoclasts / 活性型ビタミンD_3 / 転写制御 / 破骨細胞分化因子 / カルシウム調節ホルモン / 発現制御 / マイクロアレイ / 1α-hydroxylase / 1α,25-dihydroxyvitamin D3 / parathyroid hormone / ステロイドホルモン / 1α-水酸化酵素 / Estrogen / BMP / myoblast / IL-6 / 受容体 / NF-κB / 筋芽細胞 / 骨誘導因子 / PHT受容体 / シグナル伝達 / IL-1 / TNFファミリー / 破骨細胞分化因子(ODF) / エストロゲン受容体 / 卵巣摘出術 / 骨誘導因子(BMP) / bone mineral density / ovariectomy / interleukin-7 / B cells / 骨代謝 / 骨髄 / 骨密度 / 卵巣摘出 / bone marrow / interleukin-6 / interleukin-1 / androgen / プロスタグランジン / インターロイキン1 / calcitonin / pit formation / osteoclast function / osteoclast formation / screening system / 吸収窩 / ポドソーム形成 / 破骨細胞前駆細胞 / 骨吸収評価系 / 骨吸収試験 / アクチンリング形成 / ポドソーム / 明帯 / チロシンフォスファーゼ / ビイフォスフォネート / cAMP / ビスフォスフォネート / アクチンリング / 破骨細胞機能評価系 / 破骨細胞形成評価系 / スクリーニング系 / interleukin 11 / interleukin 6 / calcium absorption / 骨 / 24,25(OH)_2D_3 / 1α,25(OH)_2D_3 / ビタミンDレセプター / インターロイキン11 / 小腸 / 肝臓 / 抗クル病因子 / Growth factor / Bone resorbing agents / the third component of complement (C3) / Calcium pump / Osteoclasts / Osteoblasts / Intestine epithelial cells / 小腸上皮細胞細胞 / オステオポンチン / 増殖因子 / 補体第3因子 / カルシウムポンプ / 小腸の吸収上皮細胞 / Bone resorption / Macrophage colony stimulating factor / Osteoblast / Bone resorbing factors / 骨髄由来ストロ-マ細胞 / 骨吸収調節因子 / マウス骨髄細胞培養 / MーCSF / 分化誘導療法 / マクロファージの分化 / マクロファージの活性化 / 骨髄性白血病細胞 / 細胞分化 / 1α,25【(OH)_2】【D_3】 / ヒト破骨細胞 / PTH / ヒト抹消血 / 共存培養 / ヒト抹消血単核細胞 / PTHレセプター / 破骨細胞分子因子(ODF) / SaOS-2 … More Except Principal Investigator 骨芽細胞 / 破骨細胞 / 骨吸収 / 活性型ビタミンD / BMP / osteoblast / Osteoclast / Osteoblast / osteoclast / OPG / M-CSF / Bone resorption / 分化 / IL-1 / RANK / ODF / RANKL / 副甲状腺ホルモン / RT-PCR / chondrocyte / 軟骨細胞 / 骨粗鬆症 / p60^<c-src> / bone resorption / 骨髄間質細胞 / GM-CSF / ビタミンD / 血小板 / 分化誘導療法 / platelet / 骨誘導因子 / 遺伝子欠損マウス / IL-11 / IL-6 / gp130 / in vivo / in vitro / E-64 / 24-hydroxylase / 1alpha-hydroxylase / parathyroid hormone / カルシウム / ビタミンD受容体 / 24-水酸化酵素 / ネフロン / 腎臓 / Hedgehog / vitamin D / bone formation / In situ hybridization / in situ hybridization / 培養細胞 / 骨細胞 / cyclooxygenase / プロスタグランジン / アラキドン酸 / シクロオキシゲナーゼ / osteoporosis / c-src / ocマウス / oc / opマウス / op / 1alpha,25(OH)_2D_3 / C3 / 1alpha, 25-dihydroxyvitamin D_3 / ODC / macrophage / 大理石骨病 / MーCSF / 1α,25(OH)_2D_3 / Osteopontin / マクロファ-ジ / LIF / オステオポンチン / ハービマイシン / 骨代謝 / 巨核球 / 蛋白質 / 骨形成 / 生理活性 / 破骨細胞活性化因子 / 分化誘導剤 / PI代謝回転阻害剤 / シアロ糖化合物 / D因子 / 神経系 / 血管系 / CDK6 / 分化能 / 遊走能 / 遺伝子網羅的解析 / ネットワーク / 神経芽細胞 / ネットワーク機構 / 骨減少症 / 骨・神経・血管 / 血管内皮細胞 / semaphorin 3A / netrin-4 / DIF / 増殖 / 肺胞マクロファージ / 骨吸収作用 / 分化誘導因子 / osteoblast differentiation / protein / serum / 血清 / 生体成分 / 骨芽細胞分化 / ubiquitin / ceramic culture system / human fibroblasts / PPF commitment factor, PCF / proplatelet_formation / megakaryocytes / proplatelet formation (PPF) / 胞体突起形成 / ユビキチン / セラミック培養 / ヒト線維芽細胞 / PPFコミットメント因子(PCF) / トロンボポエチン(TPO) / 胞体突起形成(prpplatelet formation, PPF) / Osteoporosis / Calcium / Inflammatory cytokines / 細胞内Ca / TNFα / 炎症性サイトカイン / PTH / 1α, 25(OH)_2D_3 / TNF / マクロファジーコロニー刺激因子 / 骨随間質細胞 / 破骨細胞形成抑制因子 / 破骨細胞分化因子 / estrogebn receptor / B lymphocyte / estrogen / 骨髄造血 / エストロゲンレセプター / Bリンパ球 / 女性ホルモン / osteoclast activiting factor / osteoclastogenesis inhibitory factor(OCIF) / osteoprotegerin(OPG) / シグナル伝達 / 破骨細胞分化因子(ODF) / 1L-1 / Gene targetting mouse / T-lymphocyte / Interferon gamma / Interleukin 18 / Tリンパ球 / インターフェロンγ / インターロイキン18 / degenerate-PCR / vitamin D receptors / cytochrome P450 / proximal convoluted tubules / 近位尿細管 / シトクロムP450 / シトクロムP-450 / 1α-水酸化酵素 / platelet-derived growth factor / phospholipase A2 / interleukin-1 / prostaglandin / ホスホリッパーゼA_2 / インターロイキン-1 / プロスタグランジンE / 血小板由来増殖因子 / ホスホリパーゼA2 / インターロイキン1 / rheumatoid arthritis / osteoblasts / osteoclasts / IL-6 receptor / 滑液 / トランスジェニックマウス / 可溶性IL-6レセプター / 慢性関節リウマチ / IL-6レセプター / Ultrastructure / Cathepsin / RGD peptide / Integrin / 細胞培養 / 微細構造 / カテプシン / RGDペプチド / インテグリン / mRNA / kidney / vitamin D receptor / myoblast / ostepblast / 筋肉 / 骨形成因子(BMP) / 間葉系細胞 / 筋芽細胞 / bone / bone marrow / stromal cells / complement 3 / C3遺伝子 / 補体第3因子(C3) / 骨 / ビタミンD欠乏 / 骨髄ストローマ細胞 / 転写調節 / 補体第3因子 / small GTP binding protein rho / PI-3 kinase / calcitonin / podosme / clear zone / ruffled border / 吸収窩 / ポドソーム形成 / Focal adhesion kinase / Pl-3キナーゼ / 低分子量G蛋白rho / PI-3キナーゼ / カルシトニン / ポドソーム / 明帯 / 波状縁 / muscle / 筋細胞 / cell culture / osteocyte / レーザー顕微鏡 / In sltu hrbridization / PAF receptor / midkine / 1alpha, 25-dihydroxyvitamin D3-24-hydroxylase / PGE2 receptor subtypes / aldosterone synthetase / P450 (11beta, aldo) / PAF acetylhydrolase / リポキシゲナーゼ / ホスホリパーゼA_2 / レチノイン酸 / ステロイド産生 / PAF / PAF受容体遺伝子 / 1α,25-(OH)_2ビタミンD-24水酸化酵素 / PGE_2受容体サブタイプ / コルチコステロン合成酵素 / シクロオキシゲナーゼ-2(COX-2) / P450(11β,aldo) / PAF受容体 / ミッドカイン / 1α,25-(OH)2ビタミンD-24水酸化酵素 / PGE2受容体サブタイプ / アルドステロン合成酵素 / P450(11β, aldo) / PAFアセチルハイドロラーゼ / vitamin D derivatives / triacylglycerol / preadipocyte / phospholipids / adipogenesis / adipocyte / ホスファチジルコリン / 脂質代謝 / デキサメタゾン / 前脂肪細胞 / トリグリセリド / リン脂質 / 脂質合成 / 脂肪細胞 / macrophage colony stimulating (M-CSF) / osteopetrosis / マクロファ-ジコロニ-剌激因子 / C3 receptor / complement / ILー1 / 116kD / 肝臓 / マウス補体第3成分 / C3レセプター / 補体第3成分 / Osteocalcin / Bone Resorption Factor / Circadian rhythm / Bone Resorption / Alveolar Bone Resorption / 組織再生法 / 骨吸収促進物質 / 細胞内プロテア-ゼ / 病態モデル / 扁平上皮癌株細胞 / カテプシンD / bisphosphonate / 骨吸収病態モデル / 概口リズム / オステオカルシン / 局所的骨吸収因子 / 概日リズム / 歯槽骨吸収 / villus / Ca-ATPase / putrescine / polyamine / Ca transport / Intestine / ポリアミン酸化酵素 / CaーATPase / ポリアミン合成阻害剤 / プトレッシン / ポリアミン / Ca吸収 / 小腸 / cell-cell interaction / osteopetosis / 1alpha, 25 (OH) _2D_3 / monocyte / 骨髄由来ストロ-マ細胞 / 骨吸収調節因子 / マクロファ-ジコロニ-刺激因子 / Lalpha, 25 (OH) _2D_3 / Macrophage fusion / Interleukin 1 / Iγ-6 / Iγ-4 / GMーCSF / 細胞融合 / インタ-ロイキン1 / ILー6 / エリトロポエチン / 赤芽球分化因子 / ガングリオシド類縁体 / TNF 変異体 / インターロイキン6 / ブロメライン / GーCSF / ビタミンD_3誘導体 / 核酸関連化合物 / 遺伝子調節 / Pax6 / エピジェネティクス / ロコモティブ / 転写因子 / エピジェネティック / 糖代謝 / 細胞・組織 / 生体分子 / フラバノン化合物デスマール / アポプトーシス / エンドヌクレアーゼ / 糖転移酵素系 / 非リン酸化RB遺伝子産物 / チロシンキナーゼ阻害剤 / 糖鎖含有リコンビナントD因子 / インスリン受容体βサブユニット自己リン酸化反応 / 造血因子MーCSF / トランスフォ-ミング増殖因子(TGF)β / 活性型ビタミンD3 / 抗癌剤排出性P糖蛋白 / 特異的チロシンキナ-ゼ阻害物質 / 脂質性合成シアロ糖化合物 / ラット骨髄前脂肪細胞株RECAー16 / アポプト-シス / AraC感受性 / MDS由来細胞株 / ミオシンL鎖キナ-ゼ阻害剤 / 蛋白リン酸化酵素阻害剤 / ピリミジンヌクレオシド化合物 / 活性化酸素 / 倍数性骨髄性白血病株細胞 / 熱ショック蛋白質 / 分化誘導療法補強剤 / アルキルエーテル非燐脂質 Less

Molecular mechanisms of nerve-vessel-bone network
- Principal Investigator
  
  SATO Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Saitama Medical University
Molecular insights of the crosstalk between locomotive and metabolic syndromes
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
巨核球・血小板に由来する骨形成促進因子の単離・同定に基づく新しい研究領域の開拓
- Principal Investigator
  
  片桐岳信
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Isolation and identification of bone morphogentic protein and its potentiator from bovine serum
- Principal Investigator
  
  KATAGIRI Takenobu
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Saitama Medical School
A study of cross-talk between the expression mechanisms of osteoclast differentiation factor (ODF) and osteoclastogenesis inhibitory factor (OCIF)Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical School
Studies on novel cytokines produced by human embryonic fibroblasts.
- Principal Investigator
  
  HIGASHIO Kanji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Saitama Medical School
破骨細胞の融合機構とその生理的意義の解明
- Principal Investigator
  
  高橋直之
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
The physiological role of osteoclast differentiation factor.
- Principal Investigator
  
  UDAGAWA Nobuyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on signal transduction in osteoclastogenesis for the development of anti-osteoporosis drugs.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
The roles of nuclear transcription factors in calcium homeostasisPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on osteoclast activiting factor expressed by osteoblasts/stromal cells
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Pathogenesis of osteoporosis : role of estrogen in bone metabolism
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo University of Pharmacy and Life Science
ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Mechanism of osteoclastogenesis inhibitory action by interleukin 18
- Principal Investigator
  
  UDAGAWA Nobuyuki, 宇田川信之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Regulation of PGE synthesis by activated cytosolic phospholipase A2 and induced cyclooxygenase-2 in osteoblasts.
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Mechanism of regulation of vitamin D metabolism at molecular level.
- Principal Investigator
  
  SHINKI Toshimasa, 新木敏正
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of bone metabolism improvement medicines based on the analysis of signal transductionPrincipal Investigator
- Principal Investigator
  
  SUDA Tasuo
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Analysis of gp130-induced signals which regulate osteclast formation and function
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of BMPs in differentiation process of osteoblasts, chondrocytes and muscle cells
- Principal Investigator
  
  YOSHIKI Susaku
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Molecular mechanisms of osteoporosis induced by estrogen deficiency.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of vitamin D and parathyroid hormone on vitamin D metabolism in the kidney.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Localization and Functions of Integrins and Proteinase in Osteoclasts
- Principal Investigator
  
  SASAKI Takahisa
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
A study for gene expression of synthetic enzymes and receptors for lipid biofactors
- Principal Investigator
  
  ICHIKAWA Atsushi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  KYOTO UNIVERSITY
Study of the mechanism of bone formation using morphological and functional analyzes
- Principal Investigator
  
  YOSHIKI Shusaku
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Study for differentiation process of osteoblasts
- Principal Investigator
  
  YAMAGUCHI Akira
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Showa University
Analysis of signaling pathways involved in polarization of osteoclasts.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of reliable screening systems for drugs which regulate bone resorption : In vitro assay systems for osteoclast formation and function.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Production and biological roles of the third component of complement in bone.
- Principal Investigator
  
  MIYAURA Chisato
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
細胞分化誘導剤の臨床応用に関する基礎的研究
- Principal Investigator
  
  斉藤政樹
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Molecular aspects of vitamin D metabolism and actionPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
細胞分化誘導剤の臨床応用に関する基礎的研究
- Principal Investigator
  
  斎藤政樹
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Jichi Medical University
Cloning of proteins produced by osteoblastic cells in response to 1alpha,25(OH)_2D_3.
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Study on Interaction between Osteoclast Progenitors and Osteoblastic Cells in Osteoclast Development.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of vitamin D_3 on differentiation of bone marrow-derived stromal cells.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Studies of the Etiology and Therapeutic Approach of Alveolar Bone Resorption
- Principal Investigator
  
  OGURA Hideaki
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Tokyo Medical and Dental University
Basic study on the risk factors of osteoporosis.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導療法剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
The Role of Cytokines in Bone Resorption and Bone Formation
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Rolo of Osteoblastic Cells in Osteoclast Development.
- Principal Investigator
  
  TAKAHASHI Naoyuki
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Role of Putrescine in Vitamin D-Dependent Intestinal Cell Differentiation.
- Principal Investigator
  
  SHINKI Toshimasa
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Establishment of the screening methods for bone-resorbing factors using in vitro osteoclast formation system.Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導療法剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Two step model for the fusion of macrophages induced by 1alpha, 25-dihydroxyvitamin D_3Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
新しい分化誘導剤の開発と分化誘導療法の基礎的研究
- Principal Investigator
  
  穂積本男
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Research Institute for Clinical Oncology, Saitama Cancer Center
Mechanisms of Osteoclast Formation
- Principal Investigator
  
  ABE Etsuko
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
Development of new assay systems for examining the relation between osteoblasts and osteoclasts, and identification of new factors controlling bone metabolismPrincipal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University, School of Dentistry
活性型ビタミンDによる細胞分化と発癌プロモーションの制御Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Showa University
Mechanisms of Fusion of Macrophages Induced by 1 ,25(OH)_2D_3Principal Investigator
- Principal Investigator
  
  SUDA Tatsuo
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Showa University
活性型ビタミンDによる細胞分化と発癌プロモーションの制御Principal Investigator
- Principal Investigator
  
  須田立雄
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Showa University

All 2015 2014 2013 2005 2004

All Journal Article Presentation Book Patent

[Book] Vitamin D, 2^<nd> edition (ed. Feldman, Pike, Glorieux)2005
- Author(s)
  Yasuda B, Higashio K, Suda T
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Donepezil prevents RANK-induced boneloss via inhibitionofosteoclast differentiation by downregulating acetylcholinesterase.2015
- Author(s)
  Sato T, Enoki Y, Sakamoto Y, Yokota K, Okubo M, Matsumoto M, Hayashi N, Usui M, Kokabu S, Mimura T, Nakazato T, Araki N, Fukuda T, Okazaki Y, Suda T, Takeda S, Yoda T.
- Journal Title
  
  Heliyon
  
  Volume: 1 Issue: 1 Pages: 1-20
- DOI
  10.1016/j.heliyon.2015.e00013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462380, KAKENHI-PROJECT-26870543
[Journal Article] Netrin-4 derived from murine vascular endothelial cells inhibits osteoclast differentiation in vitro and prevents bone loss in vivo.2014
- Author(s)
  Matsumoto, Masahiko Okubo, Keisuke Nakashima, Masayuki Yamato, Teruo Okano, Toru Fukuda, Dai Chida, Yuuki Imai, Hisataka Yasuda, Tatsuji Nishihara, Masumi Akita, Hiromi Oda, Yasushi Okazaki, Tatsuo Suda, Tetsuya Yoda
- Journal Title
  
  FEBS Lett.
  
  Volume: 588 Issue: 14 Pages: 2262-2269
- DOI
  10.1016/j.febslet.2014.05.009
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25253090, KAKENHI-PROJECT-26293432
[Journal Article] The Paired-box Domain Transcription Factor Pax6 Binds to the Upstream Region of the TRAP Gene Promoter and Suppresses RANKL-induced Osteoclast Differentiation2013
- Author(s)
  Kogawa M, Hisatake K, Atkins GJ, Findlay DM, Enoki Y, Sato T, Gray PC, Kanesaki-Yatsuka Y, Anerson PH, Wada S, Kato N, Fukuda A, Katayama S, Tsujimoto M, Yoda T, Suda T, Okazaki Y, Matsumoto M
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Issue: 43 Pages: 31299-31312
- DOI
  10.1074/jbc.m113.461848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460354, KAKENHI-PROJECT-25462380
[Journal Article] Feldman, Vitamin D and osteoclastogenesis2005
- Author(s)
  Hisataka Yasuda, Kanji Higashio, Tatsuo Suda
- Journal Title
  
  In Vitamin D, 2^<nd> edition (ed. D. W. Pike, and F. Glorieux) (Elsevier)
  
  Pages: 665-685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and osteoclastogenesis2005
- Author(s)
  Yasuda H, Higashio K, Suda T
- Journal Title
  
  Vitamin D, Elsevier 2^<nd> Edition
  
  Pages: 665-685
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] The origin and evolution of bone tissue -prologue-2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  The Bone 18
  
  Pages: 421-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Recent advance in basic research for osteoporosis2004
- Author(s)
  Tatsuo Suda, Chisato Miyaura
- Journal Title
  
  Nippon Rinsho 62 (supplement 2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Suda T
- Journal Title
  
  Proceedings of the Japan Academy, Ser.B 80(9)
  
  Pages: 407-421
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] 硬組織の起源と進化序説2004
- Author(s)
  須田立雄
- Journal Title
  
  The Bone 18(4)
  
  Pages: 421-426
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  Proceedings of The Japan Academy, Ser. B 80
  
  Pages: 407-421
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] 骨粗鬆症の成因研究の現状2004
- Author(s)
  須田立雄, 宮浦千里
- Journal Title
  
  日本臨床 62(2)
  
  Pages: 13-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] ビタミンDと骨2004
- Author(s)
  須田立雄
- Journal Title
  
  Osteoporosis Japan 12(2)
  
  Pages: 356-357
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone -How does vitamin D regulate bone formation and resorption?-2004
- Author(s)
  Suda T
- Journal Title
  
  Proceedings of The Japan Academy, Ser.B 80(9)
  
  Pages: 407-421
- Data Source
  KAKENHI-PROJECT-15390465
[Journal Article] Vitamin D and bone2004
- Author(s)
  Tatsuo Suda
- Journal Title
  
  Osteoporosis Japan 12
  
  Pages: 356-357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390465
[Patent] 動脈硬化の治療剤2005
- Inventor(s)
  須田立雄、片桐岳信、東尾侃二、後藤雅昭、小平邦彦
- Industrial Property Rights Holder
  埼玉医科大学、中外製薬
- Industrial Property Number
  2005-198977
- Filing Date
  2005-07-07
- Data Source
  KAKENHI-PROJECT-16390533
[Patent] 動脈硬化の治療剤2005
- Inventor(s)
  須田立雄, 片桐岳信, 東尾侃二, 後藤雅昭, 小平邦彦
- Industrial Property Rights Holder
  埼玉医学大学, 中外製薬
- Industrial Property Number
  2005-198977
- Filing Date
  2005-07-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390533
[Presentation] DNAのメチル化を介した骨芽細胞分化のエピジェネティクス制御2015
- Author(s)
  大久保正彦, 松本征仁, 榎木祐一郎, 佐藤毅, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第33回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京都新宿区)
- Year and Date
  2015-07-22
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] 新たな破骨細胞分化抑制因子としてのPax6の機能解析2015
- Author(s)
  大久保正彦, 松本征仁, 甲川昌和, 八塚由紀子, 榎木祐一郎, 佐藤毅, 片山茂裕, 須田立雄, 岡﨑康司, 依田哲也
- Organizer
  第69回日本口腔科学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Self-limiting system of osteoclast differentiation by the Paired-box Domain Transcription factor Pax62013
- Author(s)
  Masahito Matsumoto, Masakazu Kogawa, Koji Hisatake, Gerald J. Atkins, David M. Findlay, Yuichiro Enoki, Tsuyoshi Sato, Peter C. Gray8, Yukiko Kanesaki-Yatsuka5, Paul H. Anderson9, Seiki Wada2, Naoki Kato4, Aya Fukuda1,7, Shigehiro Katayama, Masafumi Tsujimoto, Tetsuya Yoda, Tatsuo Suda, Yasushi Okazaki
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] Dual functional roles of Pax6 in the regulation of bone and glucose metabolism Osteoclast Differentiation.2013
- Author(s)
  Kogawa, M., Hisatake, K., Atkins, G.J., Findlay, D.M., Enoki, Y., Sato, Tsuyoshi, Gray, P, Wada, S., Kato, N., Fukuda, A., Katayama, S., Tsujimoto, M., Yoda, T., Suda, T., Okazaki, Y., and Matsumoto, M.
- Organizer
  ASBMR
- Place of Presentation
  Maryland USA
- Data Source
  KAKENHI-PROJECT-25462380

1. TAKAHASHI Naoyuki (90119222)

# of Collaborated Projects: 24 results

# of Collaborated Products: 0 results
2. MIYAURA Chisato (20138382)

# of Collaborated Projects: 19 results

# of Collaborated Products: 0 results
3. SHINKI Toshimasa (90138420)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
4. KATAGIRI Takenobu (80245802)

# of Collaborated Projects: 16 results

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5. UDAGAWA Nobuyuki (70245801)

# of Collaborated Projects: 16 results

# of Collaborated Products: 0 results
6. ABE Etsuko (70119147)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
7. TAKITO Jiro (00197237)

# of Collaborated Projects: 7 results

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8. JIMI Eijiro (40276598)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
9. TANAKA Hirofumi (30146899)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
10. SASAKI Takahisa (50129839)

# of Collaborated Projects: 6 results

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11. 斎藤政樹 (60012762)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
12. YAMAGUCHI Akira (00142430)

# of Collaborated Projects: 5 results

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13. 穂積本男 (50113478)

# of Collaborated Projects: 5 results

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14. HE Jin Cheng (10205049)

# of Collaborated Projects: 4 results

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15. AKIYAMA Shuichi (70276591)

# of Collaborated Projects: 4 results

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16. 高久史麿 (40048955)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
17. YOSHIKI Shusaku (30085740)

# of Collaborated Projects: 3 results

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18. TAKAMI Masamichi (80307058)

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19. 武市紀年 (40002133)

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20. 水野左敏 (60072930)

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21. OKAZAKI YASUSHI (80280733)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
22. FUKUDA Toru (20301492)

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23. Matsumoto Masahito (90321819)

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# of Collaborated Products: 5 results
24. SATO TSUYOSHI (60406494)

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25. YOKOSE Satoshi (90245803)

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# of Collaborated Products: 0 results
26. IKEDA Tohru (00211029)

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27. HIGASHIO Kanji (20337603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
28. SHIMA Nobuyuki (30337604)

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29. 梅沢一夫 (70114402)

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30. 吉田弥太郎 (80064525)

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31. 田原栄一 (00033986)

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32. NAKACHI YUTAKA (10522097)

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33. SUGAHARA IZUMI (10633000)

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34. YASUNAMI YOICHI (00166521)

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35. OGURA Hideaki (20013831)

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36. MUROTA Sei-itsu (50072989)

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37. MATSUMOTO Akira (40064365)

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38. KATO Yuzo (20014128)

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39. ENOMOTO Shoji (40013940)

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40. ICHIKAWA Atsushi (10025695)

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# of Collaborated Products: 0 results
41. NARUMIYA Shuh (70144350)

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42. ISHIMURA Yuzuru (40025599)

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43. OKAMOTO Mitsuhiro (90028613)

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44. INOUE Keizo (30072937)

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45. OZAWA Hidehiro (60018413)

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46. KUMEGAWA Masayoshi (40049367)

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47. SUZUKI Fujio (40028717)

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48. SASAKI Satoshi (80013803)

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49. KUROIWA Mie (90153395)

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50. TACHIKAWA Tetsuhiko (10085772)

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51. KUDO Ichiro (30134612)

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52. ISHIMI Yoshiko (50154159)

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53. ENDO Noriko (80297605)

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54. KAMIJO Ryutaro (70233939)

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55. NISHIHARA Tatsuji (80192251)

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56. YODA Testuya (60242210)

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57. 桃井隆 (40143507)

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58. 黒木登志夫 (90006073)

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59. 粕壁隆 (50152658)

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60. 高山浩明 (00012609)

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61. 清水孝雄 (80127092)

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62. 臼井通彦 (10453630)

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63. 竹田秀 (30376727)

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65. 古株彰一郎 (30448899)

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66. GOTO Masaaki

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67. TOMOYASU Akihiro

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68. KODAIRA Kunihiko

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69. 後藤雅行

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70. 久武幸司

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SUDA TATSUO 須田 立雄

須田 立雄 スダ タツオ

SUDA Tatsuo 須田 立雄

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A study of cross-talk between the expression mechanisms of osteoclast differentiation factor (ODF) and osteoclastogenesis inhibitory factor (OCIF)Principal Investigator

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The roles of nuclear transcription factors in calcium homeostasisPrincipal Investigator

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ヒトPTH受容体遺伝子の導入によるヒト破骨細胞形成系の確立Principal Investigator

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Pathogenesis of bone loss due to estrogen deficiency : Relationship between increased B-lymphopoiesis and bone resorption.Principal Investigator

SUDA TATSUO 須田立雄

須田立雄スダタツオ

SUDA Tatsuo 須田立雄