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TAKEDA NAOKI  竹田 直樹

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TAKEDA Naoki  竹田 直樹

竹田 直樹  タケダ ナオキ

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Researcher Number 90304998
Other IDs
Affiliation (Current) 2025: 熊本大学, 生命資源研究・支援センター, 助教
Affiliation (based on the past Project Information) *help 2010 – 2023: 熊本大学, 生命資源研究・支援センター, 助教
2015: 熊本大学, 生命資源研究支援センター, 助教
2014 – 2015: 熊本大学, 学内共同利用施設等, 助教
2013: 熊本大学, 生命資源教育支援センター, 助教
2012: 熊本大学, 生命資源研究支援センター, 助教 … More
2011: 熊本大学, 生命資源・研究支援センター, 教授
2008 – 2011: 熊本大学, 生命資源・研究支援センター, 助教
2009: 熊本大学, 生命資源研究支援センター生物資源発研究部門技術開発分野, 助教
2008: Kumamoto University, 生命資源研究支援センター, 助教
2007 – 2008: Kumamoto University, 生命資源研究・支援センター, 助教
2005 – 2006: 熊本大学, 生命資源研究・支援センター, 助手
2003: 熊本大学, 生命資源研究・支援センター, 助手
2002: 熊本大学, 動物資源開発研究センター, 助手
2000: 熊本大学, 動物資源開発研究センター, 助手 Less
Review Section/Research Field
Principal Investigator
Obstetrics and gynecology / Laboratory animal science / Obstetrics and gynecology
Except Principal Investigator
Experimental pathology / Gastroenterology / Basic Section 53010:Gastroenterology-related / General anatomy (including histology/embryology) / Laboratory animal science / Biological pharmacy
Keywords
Principal Investigator
精子 / 核凝縮 / haploinsufficiency / Protamine / ES細胞 / 遺伝子改変マウス / ミトコンドリア / 鞭毛 / 疾患モデル / ジーンターゲティング … More / ES細胞 / 発生・分化 / ノックアウトマウス / プロタミン / 鞭毛運動 … More
Except Principal Investigator
HAI-1 / トランスジェニックマウス / HLA-DR / 潰瘍性大腸炎 / HAI-2 / 遺伝子改変マウス / matriptase / 上皮細胞 / プロテアーゼ / モデルマウス / HLA / ERAI / Akaluc / 発光レポーター / 動物モデル / 小胞体ストレス / 炎症性腸疾患 / マウス / 雄性生殖管 / 男性生殖器 / 上皮・間葉間相互作用 / 発生・分化 / 細胞・組織 / 発癌微小環境 / 発がん微小環境 / 腫瘍 / SPINT1 / SPINT2 / がん細胞浸潤性増殖 / 腫瘍微小環境 / 上皮機能 / 上皮完全性維持機構 / 細胞膜結合プロテアーゼ / 腸管上皮細胞 / 腸管上皮 / PAR-2 / HAI-2/SPINT2 / HAI-1/SPINT1 / 膜結合プロテアーゼ / プロテアーゼ制御 / 上皮完全性 / がん組織微小環境 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 国際研究者交流 / 若手支援 / 膵前駆細胞 / Glp-1受容体 / 内外分泌細胞 / 膵再生分子機構 / ノックインマウス / Glp1受容体 / 内分泌細胞 / 細胞分化 / ベータ細胞 / ヒトES細胞 / 細胞分化誘導 / 膵内外分泌細胞 / 潰瘍生大腸炎 / 疾患モデル動物 / CRISPR/Cas9システム / 癌 / マトリプターゼ / 発がん / HAI / 浸潤・転移 / がん細胞微小環境 / 上皮組織 / 浸潤転移 / 発癌 / プロテアーゼインヒビター / 実験病理学 / 病理学 / 行動 / 可変型相同組換え / ヒト化マウス / 行動パターン / 糖尿病 / 膵炎 / 野生マウス / 細胞接着 / 動脈硬化 / ノックアウトマウス / Hic-5 / macrophage-stimulating protein / HGF activator / 上皮形態形成 / 膜型プロテアーゼ / 膜型プロテアーゼインヒビター / conditional knockout / 分子 / 遺伝子トラップ / 胚性幹細胞 / 挿入変異マウス / Crel loxシステム Less
  • Research Projects

    (16 results)
  • Research Products

    (49 results)
  • Co-Researchers

    (145 People)
  •  Analysis of the onset site and pathological progression process of ulcerative colitis in model mice with luminescence reporter gene

    • Principal Investigator
      Irie Atsushi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Kumamoto University
  •  Analysis of transgenic male infertile mice using ARTPrincipal Investigator

    • Principal Investigator
      takeda naoki
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  Analysis of crosstalk between epididymal and prostatic epithelial cells in male infertile mice

    • Principal Investigator
      YOSHINAGA Kazuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Kumamoto University
  •  Regulation of protease activities on the epithelial cell surface and its significance in epithelial disorders.

    • Principal Investigator
      Kataoka Hiroaki
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Miyazaki
  •  Regenerative mechanisms of pancreatic endocrine and exocrine cells

    • Principal Investigator
      KO SHIGERU
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Keio University
  •  Identification and analyses of colitis-associated gene segment using colitis-model mice by CRISPR/Cas9 system.

    • Principal Investigator
      Irie Atsushi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kumamoto University
  •  Regulation of protease activities on the epithelial cell surface and its significance in epithelial disorders.

    • Principal Investigator
      KATAOKA HIROAKI
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Miyazaki
  •  Analysis of Protamin2deficient mousePrincipal Investigator

    • Principal Investigator
      TAKEDA Naoki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Genetic studies on unique phenotypes in MSM/Ms mouse strain

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  Regulation of proteolysis on epithelial cell membrane and its implication in the epithelial disorders

    • Principal Investigator
      KATAOKA Hiroaki
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Miyazaki
  •  Characterization and functional analyses of Hic-5 deficient mice

    • Principal Investigator
      KANEYAMA Shuri
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Showa University
  •  Analyses of Sperm nuclear condensation in Protamine KO micePrincipal Investigator

    • Principal Investigator
      TAKEDA Naoki
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  無力精子症様を示す遺伝子改変マウスの機能解析Principal Investigator

    • Principal Investigator
      竹田 直樹
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  精子の機能障害による生殖不全機構の解明Principal Investigator

    • Principal Investigator
      竹田 直樹
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Kumamoto University
  •  可変型遺伝子トラップによる挿入突然変異マウス作製とそのカタログ化

    • Principal Investigator
      ARAKI Kimi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University

All 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] 精巣上体の発生・分化:遺伝子改変マウスを用いたアプローチ2020

    • Author(s)
      14.奥野知世,石坂駿行,川畑遊星,竹田直樹,吉信公美子,荒木喜美,吉永一也
    • Journal Title

      熊本大学医学部保健学科紀要

      Volume: 16 Pages: 1-8

    • NAID

      120006795668

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08493
  • [Journal Article] Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine2019

    • Author(s)
      Kawaguchi Makiko、Yamamoto Koji、Takeda Naoki、Fukushima Tsuyoshi、Yamashita Fumiki、Sato Katsuaki、Kitamura Kenichiro、Hippo Yoshitaka、Janetka James W.、Kataoka Hiroaki
    • Journal Title

      Communications Biology

      Volume: 2 Issue: 1 Pages: 11-11

    • DOI

      10.1038/s42003-018-0255-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06964, KAKENHI-PROJECT-18K08237, KAKENHI-PROJECT-18K17029, KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-17K08764
  • [Journal Article] Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background.2016

    • Author(s)
      Shen, J., Shi, D., Suzuki, T., Xia, Z., Zhang, H., Araki, K., Wakana, S., Takeda, N., Yamamura, K., Jin, S. and Li. Z.
    • Journal Title

      Lab. Invest.

      Volume: in press Issue: 6 Pages: 1-12

    • DOI

      10.1038/labinvest.2016.39

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-16K07093
  • [Journal Article] Relationship between Cnm-positive Streptococcus mutans and cerebral microbleeds in humans.2015

    • Author(s)
      Miyatani F, Kuriyama N, Watanabe I, Nomura R, Nakano K, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Mizuno T, Tamura A, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M, Ihara M, Kanamura N, Friedland RP, Watanabe Y.
    • Journal Title

      Oral Diseases

      Volume: 21 Issue: 7 Pages: 886-893

    • DOI

      10.1111/odi.12360

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11363, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26861835
  • [Journal Article] Association of hair dye use with circulating levels of sex hormones in premenopausal Japanese women.2015

    • Author(s)
      Nagata C, Wada K, Tsuji M, Hayashi M, Takeda N, Yasuda K.
    • Journal Title

      Eur J Public Health

      Volume: 25 Issue: 5 Pages: 895-9

    • DOI

      10.1093/eurpub/ckv020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Meikin is a conserved regulator of meiosis-I-specific kinetochore function2015

    • Author(s)
      Kim, J., Ishiguro, K., Nambu, A., Akiyoshi, B., Yokobayashi, S., Kagami, A., Ishiguro, T., Pendas, A.M., Takeda, N., Sakakibara, Y., Kitajima, T.S., Tanno, Y., Sakuno, T., and Watanabe, Y.
    • Journal Title

      Nature

      Volume: 517 Issue: 7535 Pages: 466-471

    • DOI

      10.1038/nature14097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25000014, KAKENHI-PUBLICLY-25125706, KAKENHI-PROJECT-26440003, KAKENHI-PROJECT-26440093, KAKENHI-PROJECT-26650072, KAKENHI-PROJECT-26711020, KAKENHI-PROJECT-221S0001
  • [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.2015

    • Author(s)
      Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
    • Journal Title

      Scientific Reports.

      Volume: 5 Issue: 1 Pages: 17205-17205

    • DOI

      10.1038/srep17205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H00905, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460399
  • [Journal Article] Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness2014

    • Author(s)
      Tamura M, Sasaki Y, Koyama R, Takeda K, Idogawa M, Tokino T
    • Journal Title

      Oncogene

      Volume: (in press) Issue: 40 Pages: 4837-4846

    • DOI

      10.1038/onc.2013.427

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23590920, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115, KAKENHI-PROJECT-25460929, KAKENHI-PROJECT-26460944, KAKENHI-PROJECT-221S0001
  • [Journal Article] Application of oocyte cryopreservation technology in TALEN-mediated mouse genome editing2014

    • Author(s)
      Nakagawa, Y., Sakuma, T., Nakagata, N., Yamasaki, S., Takeda, N., Ohmuraya, M. and Yamamoto, T.
    • Journal Title

      Exp Anim

      Volume: 63 Issue: 3

    • NAID

      130004677827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Screening Methods to Identify TALEN-Mediated Knockout Mice2014

    • Author(s)
      Nakagawa, Y., Yamamoto, T., Suzuki, K., Araki, K., Takeda, N., Ohmuraya, M. and Sakuma, T.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice2014

    • Author(s)
      Susa K, Sohara E, Rai T, Zeniya M, Mori Y, Mori T, Chiga M, Nomura N, Nishida H, Takahashi D, Isobe K, Inoue Y, Takeishi K, Takeda N, Sasaki S, Uchida S
    • Journal Title

      Hum Mol Genet

      Volume: 23 (19) Issue: 19 Pages: 5052-60

    • DOI

      10.1093/hmg/ddu217

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659412, KAKENHI-PROJECT-24790836, KAKENHI-PROJECT-25221306, KAKENHI-PROJECT-25670406, KAKENHI-PROJECT-26670428, KAKENHI-PROJECT-26860628, KAKENHI-PROJECT-221S0001
  • [Journal Article] Determining C-Myb protein levels can isolate functional hematopoietic stem cell subtypes.2014

    • Author(s)
      Sakamoto H, Takeda N, Arai F, Hosokawa K, Garcia P, Suda T, Frampton J, Ogawa M
    • Journal Title

      Stem Cells

      Volume: 33 Issue: 2 Pages: 479-490

    • DOI

      10.1002/stem.1855

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-24591400, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-26293228, KAKENHI-PROJECT-26670471, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-26221309
  • [Journal Article] Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity2011

    • Author(s)
      Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, Nezu Y, Yoshikawa T, Fukushima T, Kataoka H
    • Journal Title

      Am J Pathol

      Volume: 179 Pages: 1815-1826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Journal Article] Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity2011

    • Author(s)
      Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, Nezu Y, Yoshikawa T, Fukushima T, Kataoka H
    • Journal Title

      American Journal of Pathology

      Volume: 179 Issue: 4 Pages: 1815-1826

    • DOI

      10.1016/j.ajpath.2011.06.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390114, KAKENHI-PROJECT-22790384, KAKENHI-PROJECT-23790250
  • [Journal Article] Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain2009

    • Author(s)
      Araki, K., Takeda, N., Yoshiki, A., Obata, Y., Nakagata, N., Shiroishi, T., Moriwaki, K. and Yamamura, K
    • Journal Title

      Mamm Genome

      Volume: 20 Issue: 1 Pages: 14-20

    • DOI

      10.1007/s00335-008-9160-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1(Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice2008

    • Author(s)
      Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H
    • Journal Title

      Am J Pathol

      Volume: 173 Pages: 464-1475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Journal Article] Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormalhair development in mice.2008

    • Author(s)
      Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H
    • Journal Title

      American Journal of Pathology 173

      Pages: 1464-1475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Journal Article] Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice.2008

    • Author(s)
      Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H
    • Journal Title

      Am.J.Pathol 173

      Pages: 1464-1475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Journal Article] 相同組換え法による遺伝子破壊マウス作製技術2007

    • Author(s)
      竹田直樹
    • Journal Title

      日本薬理学雑誌 129巻5号

      Pages: 330-336

    • NAID

      10019727891

    • Data Source
      KAKENHI-PROJECT-19591898
  • [Presentation] ゲノム編集技術を用いた不妊モデルマウスの作2019

    • Author(s)
      竹田直樹、小林千余子、荒木喜美
    • Organizer
      平成30年度文部科学省新学術領域研究 学術研究支援基盤形成 先端モデル動物支援プラットフォーム 成果発表会
    • Data Source
      KAKENHI-PROJECT-17K07139
  • [Presentation] プロタミン1の精子成熟過程における影響2019

    • Author(s)
      竹田 直樹,荒木 喜美
    • Organizer
      日本動物学会 第90回大会
    • Data Source
      KAKENHI-PROJECT-17K07139
  • [Presentation] プロタミン2遺伝子改変マウスは精子死滅症を来す2018

    • Author(s)
      竹田直樹、小林千余子、荒木喜美
    • Organizer
      日本動物学会第89回大会(札幌)
    • Data Source
      KAKENHI-PROJECT-17K07139
  • [Presentation] プロタミン2遺伝子改変マウスの作製と解析2018

    • Author(s)
      竹田直樹、小林千余子、荒木喜美
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K07139
  • [Presentation] 発生工学的手法を用いた 遺伝子改変不妊モデルマウスの解析2017

    • Author(s)
      竹田 直樹,小林千余子,吉永 一也, 古島 謙亮,高宗 和史, 李 正花, 安部 眞一, 相澤 慎一,山村 研一, 荒木 喜美
    • Organizer
      日本動物学会 第88回大会
    • Data Source
      KAKENHI-PROJECT-17K07139
  • [Presentation] Hai-2 is essential for the maintenance of intestinal epithelium in mice.2017

    • Author(s)
      Kataoka H, Kawaguchi M, Yamamoto K, Seto A, Fukushima T, Shimomura T, Takeda N
    • Organizer
      ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05175
  • [Presentation] 大腸上皮細胞の小胞体ストレスがHLA-DR4トランスジェニックマウスのホモ接合体に発症する大腸炎の病因である2016

    • Author(s)
      入江 厚、今村 隆寿、道端 弥生、久保 多津子、竹田 直樹、澁谷 功、十河 真司、荒木 喜美、西村 泰治
    • Organizer
      第25回日本組織適合性学会大会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-22
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] Endoplasmic reticulum stress causes ulcerative colitis-like severe colitis in the homozygotes of HLA-DR4 transgenic mice.2016

    • Author(s)
      IRIE A, MICHIBATA Y, KUBO T, IMAMURA T, TAKEDA N, ARAKI K, SHIBUYA I, SOGO S, NISHIMURA Y
    • Organizer
      第45回日本免疫学会学術集会
    • Place of Presentation
      宜野湾
    • Year and Date
      2016-12-05
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] Aberrant accumulation of HLA-DR and reduced mucin production in colonic epithelial cells of HLA-DR4 transgenic mice and ulcerative colitis patients.2016

    • Author(s)
      Irie A, Imamura T, Michibata Y, Kubo T, Takeda N, Shibuya I, Sogo S, Araki K, Nishimura Y.
    • Organizer
      16th International Congress of Immunology
    • Place of Presentation
      Melbourune, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] Endoplasmic reticulum stress causes ulcerative colitis-like severe colitis in the homozygotes of HLADR4 transgenic mice.2015

    • Author(s)
      入江厚、道端弥生、久保多津子、今村隆寿、竹田直樹、荒木喜美、 渋谷功、十河真司、西村泰治
    • Organizer
      第44回日本免疫学会総会
    • Place of Presentation
      札幌
    • Year and Date
      2015-11-28
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] Circulating miRNAs as liquid biopsy in Alzheimer's disease and pancreatic cancer toward application for the diagnosis2015

    • Author(s)
      Yu Ninose, Sayaka Okamoto, Ikuko Takeda, Tetsuya Takahashi, Masayasu Matsumoto
    • Organizer
      Extracellular Biomarkers Summit
    • Place of Presentation
      Hyatt Regency Cambridge, Boston, U.S.A.
    • Year and Date
      2015-03-16
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] マウス肝組織発生中の肝芽細胞におけるTGF-betaシグナリング経路の機能2015

    • Author(s)
      横内裕二,竹田直樹,佐々木洋,山村研一,竹之下誠一
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] HLA-DR4トランスジェニックマウスのホモ接合体に発症するリンパ組織形成不全と大腸炎の解析2015

    • Author(s)
      入江厚、道端弥生、久保多津子、今村隆寿、竹田直樹、荒木喜美、 渋谷功、十河真司、西村泰治
    • Organizer
      25th Kyoto T cell Conference
    • Place of Presentation
      京都
    • Year and Date
      2015-05-15
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] 大腸上皮細胞の小胞体ストレスがHLA-DR4トランスジェニックマウスのホモ接合体に発症する大腸炎の病因である2015

    • Author(s)
      入江厚、道端弥生、久保多津子、今村隆寿、竹田直樹、荒木喜美、 渋谷功、十河真司、西村泰治
    • Organizer
      第24回日本組織適合性学会大会
    • Place of Presentation
      水戸
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of circulating miRNAs in plasma from patients with Alzheimer's disease toward application for the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第37回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] p53 family network and tumor suppression2014

    • Author(s)
      Sasaki Y, Tamura, M, Takeda K, Idogawa M, Maruyama R, Suzuki H, Shinomura Y, Tokino T
    • Organizer
      The 3rd International Symposium on Genetic Regulation and Targeted Therapy of Cancer and 5th Symposium of A3 Foresight Program
    • Place of Presentation
      Zhangjiajie, China
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] アルツハイマー患者における血漿中マイクロRNAの解析と診断への応用, Analysis of plasma miRNAs in patients with Alzheimer's disease as applied to the diagnosis2014

    • Author(s)
      二瀬由宇、岡田沙矢香、竹田育子、高橋哲也、松本昌泰、田原栄俊
    • Organizer
      第6回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島(広島県・広島市)
    • Year and Date
      2014-08-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 細胞膜結合型プロテアーゼインヒビターHAI-1は表皮角化細胞の形態形成に必須である.2012

    • Author(s)
      川口真紀子、竹田直樹、星子新理、福島剛、片岡寛章
    • Organizer
      第17回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      浜松市
    • Year and Date
      2012-08-17
    • Data Source
      KAKENHI-PROJECT-24390099
  • [Presentation] HAI-1は表皮角化細胞のアクチン細胞骨格を制御し、細胞接着・形態維持に重要な役割を果たしている2011

    • Author(s)
      川口真紀子, 竹田直樹, 澤口朗, 佐藤悠子, 星子新理, 福島剛, 片岡寛章
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] A Novel ES cell Line ,Baltha1, for GeneTargeting, with HighGermline-Differentiating Potency2011

    • Author(s)
      竹田直樹、 黒田和子、 吉松麗加、 中川佳子
    • Organizer
      日本動物学会第82回大会
    • Place of Presentation
      旭川市大雪クリスタルホール(北海道)
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-22591828
  • [Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for the integrity of intestinal epithelium.2010

    • Author(s)
      Kawaguchi M, Fukushima T, Takeda N, Hoshiko S, Yorita K, Kohama K, Orikawa H, Baba T, Kataoka H
    • Organizer
      Experimental Biology 2010
    • Place of Presentation
      Anaheim CA, USA.
    • Year and Date
      2010-04-26
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] 表皮の形態形成におけるHepatocyte growth factor activator inhibitor type 1(HAI-1)の意義2010

    • Author(s)
      川口真紀子、竹田直樹、澤口朗、星子新理、福島.剛、片岡寛章
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] Hepatocyte growth factor activator inhibitor type 1(HAI-1)is required for the integrity of intestinal epithelium.2010

    • Author(s)
      Kawaguchi M, Fukushima T, Takeda N, Hoshiko S, Yorita K, Kohama K, Orikawa H, Baba T, Kataoka H
    • Organizer
      Experimental Biology 2010(EB2010)
    • Place of Presentation
      Anaheim, USA
    • Year and Date
      2010-04-27
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] Hepatocyte growth factor activator inhibitor type 1(HAI-1) is required for the integrity of intestinal epithelium2010

    • Author(s)
      Kawaguchi M, Fukushima T, Takeda N, Hoshiko S, Yorita K, Kohama K, Orikawa H, Baba T, Kataoka H
    • Organizer
      Experimental Biology 2010
    • Place of Presentation
      Anaheim CA, USA
    • Year and Date
      2010-04-26
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] Hepatocyte 9rowth factor activator inhibitor type 1 (HAI-1)は表皮、毛の形態形成に重要である2008

    • Author(s)
      川口真紀子, 澤口朗, 小濱和代, 竹田直樹, 福島剛, 片岡寛章
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390114
  • [Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for maintaining keratinocyte morphology through regulation of PAR-2-dependent p38 MAP kinase signaling.

    • Author(s)
      Kawaguchi M, Takeda N, Kanemaru A, Sawaguchi A, Fukushima T, Kataoka H.
    • Organizer
      ASBMB Special Symposia Series: Membrane-Anchored Serine Proteases
    • Place of Presentation
      Potomac MD, USAPotomac MD, USA
    • Data Source
      KAKENHI-PROJECT-24390099
  • [Presentation] HLA-DR4トランスジェニックマウスのホモ接合体のリンパ組織形成不全と大腸炎および肺炎の発症

    • Author(s)
      入江 厚、道端 弥生、久保 多津子、今村 隆寿、矢津田 旬二、竹田 直樹、荒木 喜美、江藤 正俊、澁谷 功、十河 真司、西村 泰治
    • Organizer
      第23回日本組織適合性学会大会
    • Place of Presentation
      長崎
    • Year and Date
      2014-09-13 – 2015-09-15
    • Data Source
      KAKENHI-PROJECT-26460972
  • [Presentation] CRISPR/Cas9による2本鎖切断・1本鎖切断を利用した場合のマウスES細胞における相同組換え効率の比較

    • Author(s)
      荒木喜美, 牟田真由美, 仙波圭, 竹田直樹, 仁木大輔, 松本健, 武田伊世, 山村研一, 大村谷昌樹, 荒木正健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Functional analysis of the TGF-β pathway in hepatoblasts during mouse hepatic histogenesis.

    • Author(s)
      Yokouchi, Y., Yoshii, D., Takeda, H., Suda, H., Inomata, Y., Yamamura, K.
    • Organizer
      第47回日本発生生物学会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2014-05-27 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Novel HLA-DR4 transgenic mice that develop sever colitis and pneumonia with serious defects in lymphoid organs

    • Author(s)
      Irie, A., Michibata, Y., Kubo, T., Imamura, T., Takeda, N., Araki, K., Sasaki, G., Shibuya, I., Sogo, S., and Nishimura, Y.
    • Organizer
      第43回日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-26460972
  • 1.  ARAKI Kimi (90211705)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 2.  KATAOKA Hiroaki (10214321)
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    # of Collaborated Products: 14 results
  • 3.  YAMAMURA Ken-ichi (90115197)
    # of Collaborated Projects: 2 results
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  • 4.  ARAKI Masatake (80271609)
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  • 5.  FUKUSHIMA Tsuyoshi (10452913)
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  • 6.  ISHIDA YOICHI (90510454)
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  • 7.  Irie Atsushi (30250343)
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  • 8.  TANAKA Hiroyuki (90433060)
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  • 9.  KANEYAMA Shuri (10338535)
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  • 144.  渡辺 嘉典
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  • 145.  及川 大輔
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