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TERASAKI Tetsuya  寺崎 哲也

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Researcher Number 60155463
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2016 – 2019: 東北大学, 薬学研究科, 教授
2017: 東北大学, 大学院薬学研究科, 教授
2017: 東北大学, 薬学部, 教授
2015: 東北大学, 大学院薬学研究科, 教授
2015: 東北大学, 薬学部, 教授 … More
2012 – 2015: 東北大学, 薬学研究科(研究院), 教授
2011: 東北大学, 薬学部薬学研究科, 教授
2007 – 2010: Tohoku University, 大学院・薬学研究科, 教授
1999 – 2008: New Industry Creation Hatchery Center, Tohoku University, Professor, 未来科学技術共同研究センター, 教授
2006: Tohoku University, Graduate School of Pharmaceutical Sciences, Professor, 大学院薬学研究科, 教授
2005: 東北大学, 未来科学共同研究センター, 教授
2001: 東北大学, 未来科学技術共同センター, 教授
1996 – 1999: Tohoku University, Department of Pharmacertics, Professor., 薬学部, 教授
1993 – 1995: University of Tokyo, Pharmaceutics, Associate Professor, 薬学部, 助教授
1990 – 1992: 金沢大学, 薬学部, 助教授
1989: 金沢大学, 薬学部, 講師 Less
Review Section/Research Field
Principal Investigator
Medical pharmacy / 応用薬理学・医療系薬学 / 医薬分子機能学 / Biological Sciences / Physical pharmacy / Biological pharmacy
Except Principal Investigator
Neurology / Physical pharmacy / Medical pharmacy / 応用薬理学・医療系薬学 … More / Neurosurgery / Biological pharmacy / Biological pharmacy / Cell biology / 医薬分子機能学 / Complex systems Less
Keywords
Principal Investigator
血液脳関門 / P-糖蛋白 / 輸送担体 / blood-brain barrier / 脳毛細血管内皮細胞 / トランスポーター / 脳 / 血液脳脊髄液関門 / conditionally immortalized cell line / 条件的不死化細胞 … More / 有機アニオン輸送系 / P-glycoprotein / 排出輸送 / 中枢解毒 / ドラッグデリバリー / ウイルス受容体 / ポリオウイルス / Brain Efflux Index法 / 排出輸送系 / 脳毛細血管 / 細胞膜輸送 / brain capillary endothelial cell / efflux transport / membrane transport / Organ tropism / Virus receptor / Poliovirus / トランスジェニックマウス / 標的絶対定量プロテオミクス / 定量プロテオミクス / リン酸化 / プロテオミクス / ABCトランスポーター / siRNA / oatp2 / アルツハイマー病 / LRP-1 / 不死化細胞クローン / グルタミン酸 / シスチン / ステロイド / ワクチン / 解毒 / 有機アニオン / protein quantification / transporter / proteomics / brain barrier / 血液くも膜関門 / 標的プロテオミクス / 網羅的プロテオミクス / 網羅的半定量プロテオミクス / 標的定量プロテオミクス / 脳関門 / 種差 / ヒト / 局在解析 / タンパク質絶対発現量 / SWATH法 / 血液脊髄関門 / 血液クモ膜関門 / 生体機能利用 / 脳・神経 / 薬学 / 脳クレアチン欠乏症 / クレアチン脳欠乏症 / クレアチントランスポーター / Efflux transport / Energy / Protection / Regulation / Neural disorders / Transporter / Brain capilary endothelial cells / Blood-brain barrieer / basic FGF / 脳内エネルギー蓄積物質 / クレアチン輸送系 / system A / system Xc^- / 酸化的ストレス / organic anion transporter3(OAT3) / ASCT / 立体選択性 / アルパラギン酸輸送 / アミロイド蛋白 / Tie2受容体 / アンジオポエチン / 密着結合 / 周皮細胞 / Oatp / Oat / 尿毒症 / 有機アニオン輸送 / 脳内エネルギー / 中枢防御 / 制御 / 中枢疾患 / membrane transporter / drug screening / brain capillary endothelial cells / culture cell / gene expression / plasma membrane / 新薬スクリーニング / 培養細胞 / 遺伝子発現系 / central nervous system detoxification / cDNA cloning / organic anion transporter / neurotransmitter / 遺伝子クローニング / 神経伝達物質 / p53 protein / tight junction protein / glucose transporter / temperature sensitive SV40T antigen gene / グルコース輸送 / GLUT-1 / 温度感受性SV40T抗原遺伝子導入トランスジェニック動物 / グルコース / トランスジェニック動物 / p53 / タイトジャンクション / グルコース輸送担体 / 温度感受性SV40T抗原遺伝子 / organic anion transport system / System Xc / estorone sulfate / acidic amino acid / cerebral detoxification / blood-cerebrospinal fluid barrier / blood-brain-barrier / 分子多様性 / D-アスパラギン酸 / L-アスパラギン酸 / システムX_c / エストロン硫酸抱合体 / 酸性アミノ酸 / organic anion transport / brain efflux index method / drug delivery / brain / 脳排出指標 / 薬物排出輸送 / 膜輸送 / Transgenic mouse / Blood-brain barrier : / Brain / Vaccine / Pharmacokinetics / 臓器選択性 / ウイルス製剤 / Transport carrier / Tumor cells / Drug delivery / Cell adhesion molecule / Blood-brain barrier / モノクローナル抗体 / ウイルス感染 / 転移 / 癌細胞 / 細胞接着因子 / 受容体 / 脳腫瘍 / 個別化 / がん / 個別化医療 / 増殖因子受容体 / 分子標的薬 / 脳疾患 / 細胞内情報伝達系 / Pharmacoproteomics / P-糖タンパク / 病態 / 可塑性 / 磁気分離 / 生理機能 / MRP / ファーマコプロテオミクス / 標的絶対プロテオミクス / pharmacoproteomics / 質量分析 / ABC transporter / High Throughput Screenint / MIANS / MRP4 / 基質認識 / 薬物分布 / 蛍光消光法 / ApoE / リポタンパク質 / 24-S-水酸化コレステロール / コレステロール / 脂質代謝 / OAT / GLUT1 / ABCG2 / Mct1 / P-gp / LXR / P-糖蛋白質 / 膜輸送複合体 / トランスポートソーム / Neprilysin / P糖タンパ / アミロイドβ蛋白 / アミノ酸輸送 / System-A / T-抗原 / トランスジェニックラット / 脈絡叢上皮細胞 / 遺伝子治療 / トラスジェニックマウス / ノックアウトマウス / 制癌剤 / 薬物分子設計 / 小腸吸収 / 遺伝子発現 / 組織標的化 / ウリジン / 卵母細胞 / アフリカツメガエル / 血液-脳脊髄関門 / 鎮痛薬 / 抗痴呆薬 / デリバリ- / エンドサイト-シス / ペプチド / 血液-脳関門 … More
Except Principal Investigator
血液脳関門 / 内皮細胞 / 血液神経関門 / 体内動態 / ファーマコキネティクス / プロテオミクス / 膠芽腫 / 血液脳脊髄液関門 / GLUT1 / vitamin C / Drug delivery system / transporter / biliary excretion / 能動輸送 / 肝取り込み / 担体輸送 / 輸送担体 / 胆汁排泄 / Pharmacokinetics / 脳脊髄液関門 / MRK-16 / ビンクリスチン / Caco-2 / 定量プロテオミクス / 血管内皮細胞 / トランスポーター / 多発性硬化症 / ドラッグデリバリーシステム / 分子機構 / レセプター / 生理活性物質 / 医薬品開発 / 薬物治療 / バイオマーカー / Claudin11 / 中枢関門 / 密着結合 / 血液クモ膜関門 / 血液脊髄関門 / Claudin-11 / 非細胞バリアー / ラミニンアイソフォーム / 炎症性ニューロパチー / ラミニン / 基底膜 / ペリサイト / 分類 / チロシンキナーゼ / Opioid Peptides / Splice Variants / Receptor Expressed Cell / Opioid Receptor / オピオイドペプチド / スプライスバリアント / 発現細胞 / オピオイド受容体 / Regulation / Disease / Cholesterol / ABC transporter / Efflux transport / Neurotoxin / Blood-Cerebrospinal Fluid Barrier / Blood-Brain Barrier / 脳内局在 / キノリン酸 / ABCG2 / ABCA1 / 制御 / 病態 / コレステロール / ABCトランスポーター / 排出輸送 / 神経毒 / transport mechanism / TR-iBRB cells / diabetes / antioxidant / oxidative stress / blood-retinal barrier / 条件的不死化細胞株 / 輸送機構 / TR-iBRB細胞 / 糖尿病 / 抗酸化物質 / 酸化的ストレス / 血液網膜関門 / multipotent stem cells / T-antigen / tissue reconstruction / differentiated cells / transgenic mouse / 造血幹細胞 / 細胞分化 / 生体組織再構築 / トランスゲニックラット / トランスゲニックマウス / 多能性幹細胞 / T-抗原 / 組織再構成 / 機能細胞 / トランスジェニックマウス / Gene / Tumor / Liposomes / アンチセンス / 抗がん剤 / エネルギー代謝 / 遺伝子 / がん / リポソーム / 薬物送達システム / hepatic uptake / recombinant P-450 / hepatic microsomes / drug metabolism / 胆管側膜小胞 / P450発現系 / 肝ミクロソーム / 薬物代謝 / Hepatocyte growth factor / Epidermal growth factor / Clearance / Growth Factor / Polypeptide / Cytokine / 上皮成長因子 / 肝細胞増殖因子 / クリアランス / 増殖因子 / ポリペプチド / サイトカイン / heredital defect / Dubin Johnson Syndrome / colning / primary active transport / organic anion / bile canalicular membrane / 輸送担体欠損ラット / ペプチド性化合物 / 肝輸送 / クローニング / 胆管側模透過 / 遺伝的変異 / Dubin Johnson症候群 / グローニング / 一次性能動輸送 / 有機アニオン / 胆管側膜透過 / Physiological pharmacokinetics / Vincristine / Monoclonal antibody / P-glycoprotein / Multi-drug resistance / vincristine / DDI / AZT / 脳血液関門 / 単離脈絡叢 / MDR / 生理学的薬物速度論 / モノクローナル抗体 / P-糖蛋白 / 多剤耐性 / P-Glycoprotein / Blood-brain barrier / Brain caillary endothelial cells / beta-Lactam antibiotics / Gene expression / Proton cotransport / Monocarboxylic acid / P糖蛋白質 / 培養細胞 / P-糖蛋白質 / 脳毛細血管内皮細胞 / β-ラクタム抗生物質 / 遺伝子発現 / プロトン共輸送 / モノカルボン酸 / UGT / CYP / 絶対量 / 代謝酵素 / タンパク質 / 質量分析 / 末梢神経障害 / 血管周細胞 / 薬学 / 免疫学 / 脳神経疾患 / 神経科学 / ギラン・バレー症候群 / プロテオーム / ギランバレー症候群 / ドラッグデリバリー / 神経免疫学 / MAPK / PKC / 網膜ペリサイト株 / リコンビナントタンパク / 網膜毛細血管内皮細胞 / 細胞増殖抑制因子 / 血管新生 / 網膜ペリサイト / CPT-11 / AUC / ファーマコダイナミクス / 5-FU / Drug Delivery System / 骨髄毒性 / 血中濃度下面積(AUC) / 最大耐用量 / 化学療法 / 抗癌剤 / 5ーフルオロウラシル / 9Lーグリオ-マ / 選択的デリバリ- / 血管透過性 / 制がん剤 / 毛細血管 / 脳腫瘍 / 二次性能動輸送 / 有機アニオン輸送系 / コリン輸送系 / リン酸輸送系 / モノカルボン酸輸送系 / 小腸刷子緑膜 / 担体介在輸送 Less
  • Research Projects

    (46 results)
  • Research Products

    (358 results)
  • Co-Researchers

    (58 People)
  •  Study of human brain barrier transport mechanism based global and targeted proteomicsPrincipal Investigator

    • Principal Investigator
      Terasaki Tetsuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Amino acid transporter-based drug development for cerebral creatine deficiency syndromePrincipal Investigator

    • Principal Investigator
      Terasaki Tetsuya
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Investigation of contribution of novel tight junction molecule at the two big central nervous system barriers and its usefulness as a therapeutic target for multiple sclerosis

    • Principal Investigator
      Uchida Yasuo
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Exploration of blood biomarker for glioblastoma

    • Principal Investigator
      Nakada Mitsutoshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University
  •  Molecular subclassification of glioblastoma based on the absolute quantitative proteomics

    • Principal Investigator
      NAKADA MITSUTOSHI
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurosurgery
    • Research Institution
      Kanazawa University
  •  Analysis and manipulation of acellular barrier in human blood-nerve barrier

    • Principal Investigator
      KANDA Takashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Yamaguchi University
  •  Clarification of molecular mechanisms of the blood-brain barrier plasticity based on quantitative targeted absolute proteomicsPrincipal Investigator

    • Principal Investigator
      Terasaki Tetsuya
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Quantitative targeted absolute proteomics-based diagnostics for personalized cancer chemotherapyPrincipal Investigator

    • Principal Investigator
      TERASAKI TETSUYA
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  小分子生体内挙動を制御する因子の組織・臓器階層における網羅的解析

    • Principal Investigator
      大槻 純男
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Tohoku University
  •  Artificial control of blood-nerve barrier : an approach toward the novel therapeutics of intractable human peripheral nervous system disorders

    • Principal Investigator
      KANDA Takashi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Yamaguchi University
  •  PROTEOMICS-BASED ANALYSIS OF BLOOD-BRAIN BARRIER TRANSPORT SYSTEMPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya (TETSUYA Terasaki)
    • Project Period (FY)
      2006 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Blood-brain barrier and blood-nerve barrier as targets of novel therapeutic strategies for neurological disorders

    • Principal Investigator
      KANDA Takashi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Yamaguchi University
  •  アミロイドβ蛋白の脳関門輸送Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Physiological role of the blood-brain barrier transportsomePrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  蛍光標識化MRP4/ABCC4を用いた新薬スクリーニング系の開発Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Analysis of blood-brain barrier transport system as the CNS elimination system for neurotoxins

    • Principal Investigator
      OHTSUKI Sumio
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tohoku University
  •  Molecular pharmacological study for characterization of new identified iropioid receptor subclass

    • Principal Investigator
      SAKURADA Shinobu
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku Pharmaceutical University
  •  網膜ペリサイト分泌血管内皮細胞増殖抑制因子の同定

    • Principal Investigator
      細谷 健一
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  Antioxidants transport via GLUT1 at the blood-retinal barrier

    • Principal Investigator
      HOSOYA Ken-ichi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  Physiological study on the transport functions at the blood-brain barrier relating to neural disorders.Principal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tohoku University
  •  cDNA cloning of blood-brain barrier neurotransmitter transporter and analysis of its physiological functionPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tohoku University
  •  Development of new drug screening system using the blood-brain barrier transporter gene expressionPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Tohoku University
  •  In vitro reconstruction of tissue function with the immortalized cell lines from transgenic mouse

    • Principal Investigator
      OBINATA Masuo
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      TOHOKU UNIVERSITY
  •  血液脳関門における薬剤排出輸送系の生理的意義Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  脈絡上皮細胞の培養細胞株の樹立Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tohoku University
  •  Functional multiplicity of blood-brain barrier transporters as a detoxifying system of the brainPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      TOHOKU UNIVERSITY
  •  Development of in vitro blood-brain barrier culture system from temperature sensitive SV40T antigen gene transgenic animalPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      TOHOKU UNIVERSITY
  •  血液脳関門における薬剤排出輸送系の生理的意義Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  ポリオウイルスの血液脳関門透過機構Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tohoku University
  •  Optimization of drug delivery system for antitumor agents based on the energy metabolism inhibition of tumor cells

    • Principal Investigator
      HARASHIMA Hideyoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokushima, Faculty of Pharmaceutical Sciences
  •  ドラッグデリバリーの空間的・時間的制御

    • Principal Investigator
      橋田 充
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyoto University
  •  Molecular design of drug efflux system modulator at blood-brain barrierPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Tohoku University
  •  Development of a method to predict in vivo drug metabolism and excretion from in vitro data with human hepatic tissues and/or recombinant proteins

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      Graduate School of Pharmaceutical Sciences, The University of Tokyo
  •  抗癌剤の前臨床データを基にしたヒトにおける動態、最大耐用量、抗腫瘍効果の予測

    • Principal Investigator
      杉山 雄一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Development of Pharmacokinetic and Safety Assessment of in vivo Virus Infection and Vaccine TherapyPrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tohoku University
      The University of Tokyo
  •  抗癌剤の最適投与計画の作成:骨髄毒性の定量化とその回避

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ドラッグデリバリーの空間的・時間的制御

    • Principal Investigator
      橋田 満
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyoto University
  •  Prediction of hepatobiliary transport of drugs : Contribution of carrier-mediated transport in the detoxication of xenobiotics

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Faculty of Pharmaceutical Sciences, The University of Tokyo
  •  Drug Delivery to the Brain Using Cell Adhesion MoleculePrincipal Investigator

    • Principal Investigator
      TERASAKI Tetsuya
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Department of Pharmacutics, Faculty of Pharmaceutical Sciences, University of Tokyo,
  •  Development of drug delivery systems for cytokines with an aim of efficient exertion of their pharmacological effect

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      Faculty of Pharmaceutical Sciences, University of Tokyo
  •  アフリカツメガエル卵母細胞発現系を用いた薬物輸送機構の分子論的解析Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanazawa University
  •  Clarification of transcellular transport mechanism of drugs utilizing tissue cultured cell systems

    • Principal Investigator
      TSUJI Akira
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kanazawa University
  •  Development of the drug delivery system for brain and cancer using the inhibitory effect of some drugs on the active efflux : Application of physiological pharmacokinetics.

    • Principal Investigator
      SUGIYAMA Yuichi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      University of Tokyo
  •  脳腫瘍時における血液ー脳関門の機能障害と制がん剤の腫瘍選択的デリバリ-

    • Principal Investigator
      辻 彰
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanazawa University
  •  細胞膜担体輸送系の基質構造認識特性を利用したドラッグデリバリ-

    • Principal Investigator
      辻 彰
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanazawa University
  •  エンドサイト-シス機構を利用した脳へのペプチドデリバリ-Principal Investigator

    • Principal Investigator
      寺崎 哲也
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kanazawa University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book Patent Other

  • [Book] Blood-brain barrier (BBB) pharmacoproteomics : a new research field opened up by quantitative targeted absolute proteomics (QTAP). Drug Delivery to the Brain–Physiological Concepts, Methodologies and Approaches, Hammarlund-Udenaes M, de Lange E, and Thorne R (Ed)2014

    • Author(s)
      Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
    • Publisher
      Springer, New York
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Book] Drug Delivery to the Brain ; Physiological Concepts, Methodologies and Approaches2014

    • Author(s)
      Tachikawa M, Uchida Y, Ohtsuki S, Terasaki T
    • Total Pages
      731
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Book] Drug Delivery to the Brain ; Physiological Concepts, Methodologies and Approaches2014

    • Author(s)
      Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
    • Total Pages
      731
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Book] トランスポーター科学最前線2008

    • Author(s)
      寺崎哲也
    • Total Pages
      23
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Book] トランスポーター科学最前線2008

    • Author(s)
      寺崎哲也
    • Total Pages
      23
    • Publisher
      京都廣川書店
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Book] A novel relationship between creatine transport at the blood-brain and blood-retinal barriers, Creatine biosynthesis, and its use for brain and retinal energy homeostasis2007

    • Author(s)
      M. Tachikawa, K. Hosoya, S. Ohtsuki, T. Terasaki
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Book] 生物薬剤学2007

    • Author(s)
      寺崎哲也
    • Total Pages
      6
    • Publisher
      南江堂
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Book] 薬物及び内因性物質の血液脳関門透過、「生物薬科学実験講座、第11巻 神経(脳)」2003

    • Author(s)
      寺崎哲也
    • Total Pages
      24
    • Publisher
      廣川書店
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Book] Blood-Brain Barrier Transport Biology and Drug Delivery to the Brain, In "Advances in Biomaterials and Drug delivery Systems"2002

    • Author(s)
      T.Terasaki
    • Total Pages
      18
    • Publisher
      Princeton Int. Pub., Co., Taipei
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Abundant Expression of OCT2, MATE1, OAT1, OAT3, PEPT2, BCRP, MDR1, and xCT Transporters in Blood-Arachnoid Barrier of Pig and Polarized Localizations at CSF- and Blood-Facing Plasma Membranes.2020

    • Author(s)
      Uchida Y, Goto R, Takeuchi H, Luczak M, Usui T, Tachikawa M, Terasaki T.
    • Journal Title

      Drug Metab Dispos

      Volume: 48(2) Issue: 2 Pages: 135-145

    • DOI

      10.1124/dmd.119.089516

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-19K16438
  • [Journal Article] 中枢疾患時の血液脳関門P糖タンパク質の機能変動機構の解明と中枢関門創薬への新展開2019

    • Author(s)
      内田康雄、臼井拓也、寺崎哲也
    • Journal Title

      医学のあゆみ

      Volume: 271(1) Pages: 104-111

    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Journal Article] オピニオン: プロテオミクスによる創薬科学の新展開2019

    • Author(s)
      寺崎哲也
    • Journal Title

      ファルマシア

      Volume: 55(12) Pages: 1097-1097

    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Journal Article] Amyloid beta(25-35) impairs docosahexaenoic acid efflux by down-regulating fatty acid transport protein 1 (FATP1/SLC27A1) protein expression in human brain capillary endothelial cells.2019

    • Author(s)
      Ochiai Y, Uchida Y, Tachikawa M, Couraud PO, Terasaki T.
    • Journal Title

      J Neurochem.

      Volume: 150(4) Issue: 4 Pages: 385-401

    • DOI

      10.1111/jnc.14722

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
  • [Journal Article] Identification of blood-brain barrier-permeable proteins derived from peripheral organ: In vivo and in vitro evidence of blood-to-brain transport of creatine kinase2019

    • Author(s)
      Sato K, Tachikawa M, Watanabe M, Miyauchi E, Uchida Y, Terasaki T
    • Journal Title

      Mol Pharm

      Volume: - Issue: 1 Pages: 247-257

    • DOI

      10.1021/acs.molpharmaceut.8b00975

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16J02046, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004
  • [Journal Article] Cluster of Differentiation 46 is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28)2019

    • Author(s)
      Kuroda H, Tachikawa M, Yagi Y, Umetsu M, Nurdin A, Miyauchi E, Watanabe M, Uchida Y, Terasaki T.
    • Journal Title

      Mol. Pharm.

      Volume: 16 Issue: 1 Pages: 292-304

    • DOI

      10.1021/acs.molpharmaceut.8b00985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16J02928, KAKENHI-PUBLICLY-18H04534
  • [Journal Article] Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood-brain barrier transporters2019

    • Author(s)
      Hoshi Yutaro、Uchida Yasuo、Kuroda Takashi、Tachikawa Masanori、Couraud Pierre-Olivier、Suzuki Takashi、Terasaki Tetsuya
    • Journal Title

      Journal of Cerebral Blood Flow & Metabolism

      Volume: - Issue: 7 Pages: 1533-1545

    • DOI

      10.1177/0271678x19868880

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
  • [Journal Article] Oxidative stress-induced activation of Abl and Src kinases rapidly induces P-glycoprotein internalization via phosphorylation of caveolin-1 on tyrosine-14, decreasing cortisol efflux at the blood-brain barrier2019

    • Author(s)
      Hoshi Y, Uchida Y, Tachikawa M, Ohtsuki S, Couraud PO, Suzuki T, Terasaki T
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: - Issue: 2 Pages: 420-436

    • DOI

      10.1177/0271678x18822801

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-17H04004
  • [Journal Article] オピニオン: 脳への薬物送達研究の新たな日の出に向けて2019

    • Author(s)
      寺崎哲也
    • Journal Title

      Drug Delivery System

      Volume: 34 (5) Pages: 334-334

    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Journal Article] Selective Protein Expression Changes of Leukocyte-Migration-Associated Cluster of Differentiation Antigens at the Blood–Brain Barrier in a Lipopolysaccharide-Induced Systemic Inflammation Mouse Model without Alteration of Transporters, Receptors or Tight Junction-Related Protein2019

    • Author(s)
      Sato K, Tachikawa M, Watanabe M, Uchida Y, Terasaki T.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 42 Issue: 6 Pages: 944-953

    • DOI

      10.1248/bpb.b18-00939

    • NAID

      130007657682

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2019-06-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
  • [Journal Article] Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis2019

    • Author(s)
      Uchida Y, Sumiya T, Tachikawa M, Yamakawa T, Murata S, Yagi Y, Sato K, Stephan A, Ito K, Ohtsuki S, Couraud PO, Suzuki T, Terasaki T.
    • Journal Title

      Mol. Neurobiol,

      Volume: 56 Issue: 3 Pages: 2039-2056

    • DOI

      10.1007/s12035-018-1207-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218, KAKENHI-PUBLICLY-18H04534
  • [Journal Article] Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.2019

    • Author(s)
      Hellinen L, Sato K, Reinisalo M, Kidron H, Rilla K, Tachikawa M, Uchida Y, Terasaki T, Urtti A.
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 60(15) Issue: 15 Pages: 5022-5034

    • DOI

      10.1167/iovs.19-27328

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22590, KAKENHI-PROJECT-18KK0446, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-17H04004, KAKENHI-PROJECT-16H06218
  • [Journal Article] Cell-type-specific spatiotemporal expression of creatine biosynthetic enzyme S-adenosylmethionine: guanidinoacetate N-methyltransferase in developing mouse brain2018

    • Author(s)
      Tachikawa M, Watanabe M, Fukaya M, Sakai K, Terasaki T, Hosoya K.
    • Journal Title

      Neurochem Res

      Volume: 43 Issue: 2 Pages: 500-510

    • DOI

      10.1007/s11064-017-2446-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15153
  • [Journal Article] Identification of blood biomarkers in glioblastoma by SWATH mass spectrometry and quantitative targeted absolute proteomics.2018

    • Author(s)
      Miyauchi E, Furuta T, Ohtsuki S, Tachikawa M, Uchida Y, Sabit H, Obuchi Wm Baba T, Watanabe M, Terasaki T, Nakada M
    • Journal Title

      PLoS One

      Volume: 13 Issue: 3 Pages: e0193799-e0193799

    • DOI

      10.1371/journal.pone.0193799

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15012, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16K15645
  • [Journal Article] 神経系のトランスポーター Up to date: 血液脳関門2018

    • Author(s)
      寺崎哲也、佐藤和貴
    • Journal Title

      Clinical Neuroscience

      Volume: 36 Pages: 692-697

    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Journal Article] Actin filament-associated protein 1 (AFAP-1) is a key mediator in inflammatory signaling-induced rapid attenuation of intrinsic P-gp function in human brain capillary endothelial cells.2017

    • Author(s)
      Yutaro Hoshi, Yasuo Uchida, Masanori Tachikawa, Sumio Ohtsuki, Tetsuya Terasaki
    • Journal Title

      Journal of Neurochemistry

      Volume: 印刷中 Issue: 2 Pages: 247-262

    • DOI

      10.1111/jnc.13960

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-14J06383, KAKENHI-PROJECT-16H06218, KAKENHI-PROJECT-16K15475
  • [Journal Article] 脳脊髄液中物質動態における脳脊髄液と接する関門の役割:脈絡叢上皮細胞、クモ膜上皮細胞、脊髄毛細血管内皮細胞における細胞膜輸送2017

    • Author(s)
      張正宇、立川正憲、寺崎哲也
    • Journal Title

      神経内科Neurological Medicine

      Volume: 87 Pages: 253-263

    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Journal Article] Quantitative Targeted Absolute Proteomics of Rat Blood-Cerebrospinal Fluid Barrier Transporters: Comparison with a Human Specimen.2015

    • Author(s)
      Uchida Y, Zhang Z, Tachikawa M, Terasaki T.
    • Journal Title

      J Neurochem

      Volume: 134 Issue: 6 Pages: 1104-1115

    • DOI

      10.1111/jnc.13147

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Journal Article] Quantitative targeted absolute proteomics for 28 human transporters in plasma membrane of Caco-2 cell monolayer cultured for 2, 3, and 4 weeks.2015

    • Author(s)
      Uchida Y, Ohtsuki S, Kamiie J, Ohmine K, Iwase R, Terasaki T.
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 30 Issue: 2 Pages: 205-208

    • DOI

      10.1016/j.dmpk.2014.11.002

    • NAID

      210000178153

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Journal Article] Quantitative targeted proteomics for understanding the blood-brain barrier: towards pharmacoproteomics.2014

    • Author(s)
      Ohtsuki S, Hirayama M, Ito S, Uchida Y, Tachikawa M, Terasaki T
    • Journal Title

      Expert Rev Proteomics

      Volume: 11 Pages: 303-313

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Journal Article] Blood-Brain Barrier Pharmacoproteomics-based Reconstruction of the In-Vivo Brain Distribution of P-glycoprotein Substrates in Cynomolgus Monkeys.2014

    • Author(s)
      Uchida Y, Wakayama K, Ohtsuki S, Chiba M, Ohe T, Ishii Y, Terasaki T
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 350 Issue: 3 Pages: 578-588

    • DOI

      10.1124/jpet.114.214536

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Journal Article] Pharmacoproteomics-based Reconstruction of In Vivo P-Glycoprotein Function at Blood-Brain Barrier and Brain Distribution of Substrate Verapamil in Pentylenetetrazole-kindled Epilepsy, Spontaneous Epilepsy and Phenytoin Treatment Models.2014

    • Author(s)
      Uchida Y, Ohtsuki S, Terasaki T
    • Journal Title

      Drug Metab Dispos

      Volume: 42 Issue: 10 Pages: 1719-1726

    • DOI

      10.1124/dmd.114.059055

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Journal Article] Quantitative Expression of Human Drug Transporter Proteins in Lung Tissues : Analysis of Regional, Gender and Inter-individual differences by Liquid Chromatography-Tandem Mass Spectrometry. E-pub ahead of print2013

    • Author(s)
      Sakamoto A, Matsumaru T, Yamamura N, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
    • Journal Title

      J Pharm Sci

      Volume: 102(9) Pages: 3395-3406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Journal Article] Quantitative expression of human drug transporter proteins in lung tissues: Analysis of regional, gender, and interindividual differences by liquid chromatography-tandem mass spectrometry.2013

    • Author(s)
      Sakamoto A, Matsumaru T, Yamamura N, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
    • Journal Title

      J. Pharm. Sci.

      Volume: 102 Issue: 9 Pages: 3395-3406

    • DOI

      10.1002/jps.23606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011
  • [Journal Article] A Study Protocol for Quantitative Targeted Absolute Proteomics (QTAP) by LC-MS/MS : Application for Inter-Strain Differences in Protein Expression Levels of Transporters, Receptors, Claudin-5, and Marker Proteins at the Blood-Brain Barrier in ddY, FVB, and C57BL/6J mice2013

    • Author(s)
      Uchida Y, Tachikawa M, Obuchi W, Hoshi Y, Tomioka Y, Ohtsuki S, Terasaki T
    • Journal Title

      Fluids and Barriers of the CNS

      Volume: 10(1) Pages: 21-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Journal Article] A Study Protocol for Quantitative Targeted Absolute Proteomics (QTAP) by LC-MS/MS: Application for Inter-Strain Differences in Protein Expression Levels of Transporters, Receptors, Claudin-5, and Marker Proteins at the Blood-Brain Barrier in ddY, FVB, and C57BL/6J mice.2013

    • Author(s)
      Y Uchida, M Tachikawa, W Obuchi, Y Hoshi, Y Tomioka, S Ohtsuki, T Terasaki
    • Journal Title

      Fluids Barriers CNS

      Volume: 10 Issue: 1 Pages: 21-21

    • DOI

      10.1186/2045-8118-10-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011, KAKENHI-PROJECT-25670067
  • [Journal Article] Identification of transporters associated with etoposide sensitivity of stomach cancer cell lines and methotrexate sensitivity of breast cancer cell lines by quantitative targeted absolute proteomics2013

    • Author(s)
      Obuchi W, Ohtsuki S, Uchida Y, Ohmine K, Yamori T, Terasaki T
    • Journal Title

      Mol Pharmacol

      Volume: 83(2) Pages: 490-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Journal Article] Quantitative atlas of blood-brain barrier transporters, receptors and tight junction proteins in rats and common marmoset.2013

    • Author(s)
      Hoshi Y, Uchida Y, Tachikawa M, Inoue T, Ohtsuki S, Terasaki T
    • Journal Title

      J Pharm Sci

      Volume: 102 Issue: 9 Pages: 3343-3355

    • DOI

      10.1002/jps.23575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689005, KAKENHI-PROJECT-23790170, KAKENHI-PROJECT-24249011, KAKENHI-PROJECT-25670067
  • [Journal Article] 定量的標的プロテオミクスに基づく胃癌・乳癌薬剤感受性関連トランスポーターの解明2013

    • Author(s)
      小渕航、寺崎哲也
    • Journal Title

      医学のあゆみ

      Volume: 245(1) Pages: 135-141

    • Data Source
      KAKENHI-PROJECT-24659063
  • [Journal Article] Peripheral nerve pericytes modify the blood-nerve barrier function and tight junctional molecules through the secretion of various soluble factors2011

    • Author(s)
      Fumitaka Shimizu, Tetsuya Terasaki, Takashi Kanda, 他4名(6, 7番目)
    • Journal Title

      J Cell Physiol

      Volume: 226 Pages: 255-266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Journal Article] Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors2011

    • Author(s)
      Y. Uchida, S. Ohtsuki, Y. Katsukura, C. Ikeda, T. Suzuki, J. Kamiie, T. Terasaki
    • Journal Title

      J Neurochem

      Volume: 117(2) Pages: 333-345

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Involvement of multidrug resistance- associated protein 4 in efflux transport of prostaglandin E2 across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins.2010

    • Author(s)
      S. Akanuma, K. Hosoya, S. Ito, M. Tachikawa, T. Terasaki, S. Ohtsuki
    • Journal Title

      J. Pharmacol. Exp. Ther 99

      Pages: 912-919

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Atrial natriuretic peptide is eliminated from the brain by natriuretic peptide receptor-C-mediated brain-to-blood efflux transport at the blood-brain barrier2010

    • Author(s)
      S. Ito, S. Ohtsuki, Y. Katsukura, M. Funaki, Y. Koitabashi, A. Sugino, S. Murata, T. Terasaki
    • Journal Title

      J. Cereb. Blood Flow Metab.

      Volume: 31 Pages: 457-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect.2010

    • Author(s)
      Nakazawa Y, Okura T, Shimomura K, Terasaki T, Deguchi Y
    • Journal Title

      J. Pharm. Sci 99

      Pages: 467-474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Establishment of a new conditionally immortalized human brain microvascular endothelial cell line retaining an in vivo blood-brain barrier function2010

    • Author(s)
      Yasuteru Sano, Tetsuya Terasaki, Takashi Kanda 他9名(7, 12番目)
    • Journal Title

      J Cell Physiol

      Volume: 225 Pages: 519-528

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Journal Article] Involvement of multidrug resistance-associated protein 4 in of flux transport of prostaglandin E2 across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins2010

    • Author(s)
      Akanuma SI, T.Terasaki
    • Journal Title

      J Pharmacol Exp Ther. E-PUB

      Pages: 912-919

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect2010

    • Author(s)
      Nakazawa Y, T.Terasaki
    • Journal Title

      J Pharm Sci. 99

      Pages: 467-474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats : involvement of creatine and taurine transporters2009

    • Author(s)
      Tachikawa M, T.Terasaki
    • Journal Title

      J Neurochem 111

      Pages: 499-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Targeted Absolute Proteomics を用いたトランスポーターの新しい研究展開2009

    • Author(s)
      大槻純男、寺崎哲也
    • Journal Title

      遺伝子医学 12

      Pages: 48-54

    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] 中枢への薬物分布におけるトランスポーターの機能と役割2009

    • Author(s)
      大槻純男、寺崎哲也
    • Journal Title

      日本薬理学雑誌 134

      Pages: 83-86

    • NAID

      10025741265

    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Targeted Absolute Proteomicsを用いたトランスポーターの新しい研究展開2009

    • Author(s)
      大槻純男、上家潤一、寺崎哲也
    • Journal Title

      遺伝子医学MOOK12

      Pages: 48-54

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] The blood-brain barrier transport and cerebral distribution of guanidinoacetate in rats: involvement of creatine and taurine transporters.2009

    • Author(s)
      achikawa M, Kasai Y, Yokoyama R, Fujinawa J, Ganapathy V, Terasaki T, Hosoya K
    • Journal Title

      J. Neurochem 111

      Pages: 499-509

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Roles of inner blood-retinal barrier organic anion transporter 3(OAT3)in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercaptopurine2009

    • Author(s)
      KI.Hosoya, T.Terasaki
    • Journal Title

      J Pharmacol Exp Ther. 329

      Pages: 87-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Targeted Absolute Proteomicsを用いたトランスポーターの新しい研究展開2009

    • Author(s)
      大槻純男、上家潤一、寺崎哲也
    • Journal Title

      遺伝子医学MOOK12

      Pages: 48-54

    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Roles of inner blood-retinal barrier organic anion transporter 3 in the vitreous/retina-to-blood efflux transport of p-aminohippuric acid, benzylpenicillin, and 6-mercapto- purine.2009

    • Author(s)
      Hosoya K, Makihara A, Tsujikawa Y, Yoneyama D, Mori S, Terasaki T, Akanuma S, Tomi M, Tachikawa M
    • Journal Title

      J Pharmacol Exp Ther 329

      Pages: 87-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Quantitative atlas of membrane transporter proteins: Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria.2008

    • Author(s)
      Kamiie J, Ohtsuki S, Iwase R, Ohmine K, Katsukura Y, Yanai K, Sekine Y, Uchida Y, Ito S, Terasaki T
    • Journal Title

      Pharm. Res 25

      Pages: 1469-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] 血液脳関門機能と薬物の分布2008

    • Author(s)
      寺崎哲也
    • Journal Title

      薬剤学 68(2)

      Pages: 88-96

    • NAID

      10025719948

    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting.2008

    • Author(s)
      Ohtsuki S, Yamaguchi H, Katsukura Y, Asashima T, Terasaki T
    • Journal Title

      J. Neurochem 104

      Pages: 147-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008

    • Author(s)
      J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
    • Journal Title

      Pharm. Res. 25

      Pages: 1469-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] 血液脳関門機能と薬物の分布2008

    • Author(s)
      寺崎哲也
    • Journal Title

      薬剤学 68(2)

      Pages: 88-96

    • NAID

      10025719948

    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008

    • Author(s)
      S. Ohtsuki, H. Yamaguchi, Y. Katsukura, T. Asashima, T. Terasaki
    • Journal Title

      J. Neurochem.

      Volume: 104 Pages: 147-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] mRNA expression levels of tight junction protein genes in mouse brain capillary endothelial cells highly purified by magnetic cell sorting2008

    • Author(s)
      S. Ohtsuki, H. Yamaguchi, Y. Katsukura, T. Asashima, T. Terasaki
    • Journal Title

      J. Neurochem 104

      Pages: 147-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier.2008

    • Author(s)
      Akanuma S, Hori S, Ohtsuki S, Fujiyoshi M, Terasaki T
    • Journal Title

      Neurochem. Int 52

      Pages: 669-674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] The endothelial cells constituting blood-nerve barrier have highly -specialized characteristics as barrier forming cells2008

    • Author(s)
      Yasuteru Sano, Tetsuya Terasaki, Takashi Kanda他(7, 11番目)
    • Journal Title

      Cell Struct Funct 32

      Pages: 139-147

    • NAID

      130004137525

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Journal Article] Peripheral nerve pericytes originatingfrom the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells2008

    • Author(s)
      Fumitaka Shimizu, Tetsuya Terasaki, Takashi Kanda他(9, 11番目)
    • Journal Title

      J Cell Physiol 217

      Pages: 388-399

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Journal Article] receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier2008

    • Author(s)
      Fujiyoshi, T. Terasaki : Expression of nuclear receptor mRNA, liver X
    • Journal Title

      Neurochem. Int. 52

      Pages: 669-674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Quantitative atlas of membrane transporter proteins : Development and application of a highly sensitive simultaneous LC/MS/MS method combined with novel in-silico peptide selection criteria2008

    • Author(s)
      J. Kamiie, S. Ohtsuki, R. Iwase, K. Ohmine, Y. Katsukura, K. Yanai, Y. Sekine, Y. Uchida, S. Ito, T. Terasaki
    • Journal Title

      Pharm. Res.

      Volume: 25 Pages: 1469-1483

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Expression of nuclear receptor mRNA and liver X receptor-mediated regulation of ABC transporter A1 at rat blood-brain barrier2008

    • Author(s)
      S. Akanuma, S. Hori, S. Ohtsuki, M. Fujiyoshi, T. Terasaki
    • Journal Title

      Neurochem. Int.

      Volume: 52 Pages: 669-674

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] BCタンパク質と個体維持機構:脳関門におけるABCトランスポーターの働きと疾患治療、「ABCタンパク質の基礎と臨床」2007

    • Author(s)
      寺崎哲也
    • Journal Title

      最新医学 62(11)

      Pages: 2461-2466

    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Multichannel liquid chromatography. tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007

    • Author(s)
      Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
    • Journal Title

      Pharm. Res.

      Volume: 24 Pages: 2281-2296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor.2007

    • Author(s)
      Ohtsuki S, Kamoi M, Watanabe Y, Suzuki H, Hori S, Terasaki T
    • Journal Title

      Biol. Pharm. Bull 30

      Pages: 1144-1146

    • NAID

      110006278407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] ABCタンパク質と個体維持機構:脳関門におけるABCトランスポーターの働きと疾患治療2007

    • Author(s)
      寺崎哲也
    • Journal Title

      最新医学 62(11)

      Pages: 2461-2466

    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells2007

    • Author(s)
      . S. Ohtsuki, H. Yamaguchi, T. Asashima, T. Terasaki
    • Journal Title

      Pharm. Res. 24

      Pages: 588-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain2007

    • Author(s)
      S. Ohtsuki, T. Terasaki
    • Journal Title

      Pharm. Res.

      Volume: 24 Pages: 1745-1758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Brain-to-blood elimination of 24S-hydroxy- cholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier.2007

    • Author(s)
      Ohtsuki S, Ito S, Matsuda A, Hori S, Abe T, Terasaki T
    • Journal Title

      J. Neurochem 103

      Pages: 1430-1438

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Multichannel Liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter.2007

    • Author(s)
      Uchida Y, Kamiie J, Ohtsuki S, Terasaki T
    • Journal Title

      Pharm. Res 24

      Pages: 2281-2296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] 薬物の薬効、毒性標的への分布:血液脳関門の透過性の評価「最新創薬学2007-薬物動態学特性の解析は創薬のキーワード-」2007

    • Author(s)
      寺崎哲也
    • Journal Title

      遺伝子医学Mook 8

      Pages: 170-177

    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] 薬物の薬効、毒性標的への分布:血液脳関門の透過性の評価2007

    • Author(s)
      寺崎哲也
    • Journal Title

      遺伝子医学Mook 8

      Pages: 170-177

    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells2007

    • Author(s)
      S. Ohtsuki, H. Yamaguchi, T. Asashima, T. Terasaki
    • Journal Title

      Pharm. Res.

      Volume: 24 Pages: 588-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] 血液脳関門の透過性の評価2007

    • Author(s)
      寺崎哲也
    • Journal Title

      遺伝子医学MOOK最新創薬学 7

      Pages: 163-169

    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Establishing a method to isolate rat brain capillary endothelial cells by magnetic cell sorting and dominant mRNA expression of multidrug resistance-associated protein 1 and 4 in highly purified rat brain capillary endothelial cells.2007

    • Author(s)
      Ohtsuki S, Yamaguchi H, Asashima T, Terasaki T
    • Journal Title

      Pharm. Res 24

      Pages: 688-694

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] 24S-Hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression.2007

    • Author(s)
      Fujiyoshi M, Ohtsuki S, Hori S, Tachikawa M, Terasaki T
    • Journal Title

      J. Neurochem 100

      Pages: 968-978

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain ; importance for CNS drug discovery and development2007

    • Author(s)
      S. Ohtsuki, T. Terasaki
    • Journal Title

      Pharm. Res. 24

      Pages: 1745-1758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] Hyperammonemia induces transport of taurine and creatine and suppresses claudin-12 gene expression in brain capillary endothelial cells in vitro.2007

    • Author(s)
      M. Belanger, T. Asashima, S. Ohtsuki, H. Yamaguchi, S. Ito, T. Terasaki
    • Journal Title

      Neurochem. Int 50

      Pages: 95-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter2007

    • Author(s)
      Y. Uchida, J. Kamiie, S. Ohtsuki, T. Terasaki
    • Journal Title

      Pharm. Res. 24

      Pages: 2281-2296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Journal Article] In vivo delivery of small interfering RNA targeting brain capillary endothelial cells.2006

    • Author(s)
      Hino T, Yokota T, Ito S, Nishina K, Kang YS, Mori S., Hori S, Kanda T, Terasaki T, Mizusawa H
    • Journal Title

      Biochem Biophys Res Commun 340(1)

      Pages: 263-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Involvement of organic anion transporters in the efflux of uremic toxins across the blood-brain barrier.2006

    • Author(s)
      Deguchi T, Isozaki K, Yousuke K, Terasaki T, Otagiri M
    • Journal Title

      J Neurochem 96(4)

      Pages: 1051-1059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells.2006

    • Author(s)
      Asashima T, Hori S, Ohtsuki S, Tachikawa M, Watanabe M, Mukai C, Kitagaki S, Miyakoshi N, Terasaki T
    • Journal Title

      Pharm Res 23

      Pages: 1235-1242

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Major involvement of low-density lipoprotein receptor- related protein 1 in the clearance of plasma free amyloid beta-peptide by the liver.2006

    • Author(s)
      Tamaki C., Ohtsuki S, Iwatsubo T, Hashimoto T, Yamada K, Yabuki C, Terasaki T
    • Journal Title

      Pharm Res 23

      Pages: 1407-1416

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice.2006

    • Author(s)
      Ohtsuki S, Kikkawa T, Hori S, Terasaki T
    • Journal Title

      Biol. Pharm. Bull 29

      Pages: 1587-1591

    • NAID

      110005663994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] In vivo delivery of small interfering RNA targeting brain capillary endothelial cells2006

    • Author(s)
      Taro Hino, Takashi Kanda, TetsuyaTerasaki, 他(8, 9 番目)
    • Journal Title

      Biochem Biophys Res Commun 340

      Pages: 263-267

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Journal Article] Brain-toblood transporters for endogenous substrates and xenobiotics at the blood-brain barrier : Overview of biology and methodology.2005

    • Author(s)
      T.Terasaki
    • Journal Title

      NeuroRx 2

      Pages: 63-72

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Increased JNK Phosphorylation and oxidative stress in response to increased glucose flux through increased GLUT1 expression in rat retinal endothelial cells.2005

    • Author(s)
      Zhou J, Deo BK, Hosoya K, Terasaki T, Obrosova IG, Brosius III FC, Kumagai AK
    • Journal Title

      Invest Ophthalmol Vis Sci 46

      Pages: 3403-3410

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Characterization of the organic cation transporter SLC22A16: a doxorubicin importer.2005

    • Author(s)
      Okabe M, Unno M, Harigae H, Kaku M, Okitsu Y, Sasaki T, Mizuno T, Shiiba K, Takanaga H, Terasaki T, Matsuno S, Sasaki I, Ito S, Abe T
    • Journal Title

      Biochem Biophys Res Commun 333

      Pages: 754-762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] rain-to-blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier : an overview of biology and methodology2005

    • Author(s)
      T.Terasaki et al.
    • Journal Title

      NeuroRx 2

      Pages: 63-72

    • Data Source
      KAKENHI-PROJECT-16390037
  • [Journal Article] Brain-to blood transporters for endogenous substrates and xenobiotics at the blood-brain barrier : Overview of biology and methodology.2005

    • Author(s)
      T.Terasaki
    • Journal Title

      NeuroRx 2

      Pages: 63-72

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Distinct spatio-temporal expression of ABCA and ABCG transporters in the developing and adult mouse brain.2005

    • Author(s)
      Tachikawa M, Watanabe M, Hori S, Fukaya M, Ohtsuki S, Asashima T, Terasaki T
    • Journal Title

      J Neurochem 95

      Pages: 294-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Journal Article] Downregulation of retinal GLUT1 in diabetes by ubiquitinylation2004

    • Author(s)
      R.Fernandes, A.L.Carvalho, A.Kumagai, R.Seica, K.Hosoya, T.Terasaki, J.Murta, P.Pereira, C.Faro
    • Journal Title

      Mol.Vis. 10

      Pages: 618-628

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier2004

    • Author(s)
      T.Nakashima, M.Tomi, K.Katayama, M.Tachikawa, M.Watanabe, T.Terasaki, K.Hosoya
    • Journal Title

      J.Neurochem. 89

      Pages: 1454-1461

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Vitamin C transport in oxidized form across the rat blood-retinal barrier2004

    • Author(s)
      K.Hosoya, A.Minamizono, K.Katayama, T.Terasaki, M.Tomi
    • Journal Title

      Invest.Ophthalmol.Vis.Sci. 45

      Pages: 1232-1239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] New approaches to in vitro models of the blood-brain barrier drug transport2003

    • Author(s)
      T.Terasaki
    • Journal Title

      Drug Discov. Today 8

      Pages: 944-954

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Establishment of conditionally immortalized rat retinal pericyte cell lines (TR-rPCT) and their application in a co-culture system using retinal capillary endothelial cell line (TR-iBRB2)2003

    • Author(s)
      T.Kondo, K.Hosoya, S.Hori, M.Tomi, S.Ohtsuki, H.Takanaga, E.Nakashima, H.Iizasa, T.Asashima, M.Ueda, M.Obinata, T.Terasaki
    • Journal Title

      Cell Struct.Funct. 28

      Pages: 145-153

    • NAID

      10011619370

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Molecular mechanism and physiological roles of the blood-brain barrier transport system.2003

    • Author(s)
      T.Terasaki
    • Journal Title

      Neuroimunology 11

      Pages: 227-235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Permeation of drugs and endogenous compounds across the blood-brain barrier.2003

    • Author(s)
      T.Terasaki
    • Journal Title

      Experimental lecture in biological pharmaceutical sciences Vol 11

      Pages: 24-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] New approach of DDS research using conditionally immortalized blood-brain barrier cell lines.2003

    • Author(s)
      T.Terasaki
    • Journal Title

      Drug Delivery System 18

      Pages: 118-125

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] In vitro study of the functional expression of organic anion transporting polypeptide 3 at rat choroid plexus epithelial cells and its involvement in the cerebrospinal fluid-to-blood transport of estrone-3-sulfate2003

    • Author(s)
      S.Ohtsuki, T.Takizawa, H.Takanaga, N.Terasaki, T.Kitazawa, M.Sasaki, T.Abe, K.Hosoya, T.Terasaki
    • Journal Title

      Mol.Pharmacol. 63

      Pages: 532-537

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Organic anion transporter 3 is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of rat brain capillary endothelial cells2003

    • Author(s)
      S.Mori, H.Takanaga, S.Ohtsuki, T.Deguchi, Y.S.Kang, K.Hosoya, T.Terasaki
    • Journal Title

      J.Cereb.Blood Flow Metab. 23

      Pages: 432-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] 血液脳関門輸送系の分子機構と生理的役割2003

    • Author(s)
      寺崎哲也
    • Journal Title

      神経免疫学(特集 IV : 血液脳関門、血液神経関門の基礎と臨床 : バリアーの生理と破綻・修復のメカニズムを探る) 11

      Pages: 227-235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Recombinant arginine deiminase as a differential modulator of inducible (iNOS) and endothelial (eNOS) nitric oxide synthetase activity in cultured endothelial cells2003

    • Author(s)
      L.Shen, W.Lin, K.Beloussow, K.Hosoya, T.Terasaki, D.K.Ann, W.C.Shen
    • Journal Title

      Biochem.Pharmacol 66

      Pages: 1945-1952

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Expression and regulation of L-cystine transporter, system x_c, in the newly developed rat retinal Muller cell line (TR-MUL)2003

    • Author(s)
      M.Tomi, T.Funaki, H.Abukawa, K.Katayama, T.Kondo, S.Ohtsuki, M.Ueda, M.Obinata, T.Terasaki, K.Hosoya
    • Journal Title

      Glia 43

      Pages: 208-217

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] 「特集号 : 細胞を用いた治療・創薬・DDS研究の最前線(編集、帯刀益夫、寺崎哲也)」条件的不死化脳関門細胞株を用いた脳へのDDS研究の新展開2003

    • Author(s)
      寺崎哲也
    • Journal Title

      Drug Delivery System 18

      Pages: 118-125

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] New approaches to in vitro models of blood-brain barrier drug transport.2003

    • Author(s)
      T.Terasaki
    • Journal Title

      Drug Discovery Today 20

      Pages: 944-954

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] New approaches to in vitro models of the blood-brain barrier drug transport2003

    • Author(s)
      T.Terasaki, S.Ohtsuki, S.Hori, H.Takanaga, E.Nakashima, K.Hosoya
    • Journal Title

      Drug Discov.Today 8

      Pages: 944-954

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390046
  • [Journal Article] Blood-Brain Barrier Transport Biology and Drug Delivery to the Brain2002

    • Author(s)
      T.Terasaki
    • Journal Title

      Advances in Biomaterials and Drug delivery Systems (Princeton Int.Pub., Co., Taipei) 18

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] Brain science up date ; Importance of the study on the blood-brain barrier efflux transport in the development of CNS acting drugs.2002

    • Author(s)
      T.Terasaki
    • Journal Title

      Brain 21 5(2)

      Pages: 201-204

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Journal Article] 脳の科学 Up Date : 中枢疾患治療薬開発における血液脳関門排出輸送研究の重要性2002

    • Author(s)
      寺崎哲也
    • Journal Title

      脳21 5(2)

      Pages: 201-204

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207104
  • [Patent] 膠芽腫マーカー及びその使用2017

    • Inventor(s)
      中田光俊,寺崎哲也、大槻純男
    • Industrial Property Rights Holder
      中田光俊,寺崎哲也、大槻純男
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-233838
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16K15645
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2011

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2011-03-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2011

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2011-01-28
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2010

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2010-10-07
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤三大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-05-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-05-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-05-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-05-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-05-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-05-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-05-22
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤三大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-05-16
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-06-17
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-05-08
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一大槻純男寺崎哲也
    • Industrial Property Rights Holder
      東北大学
    • Filing Date
      2008-06-17
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Patent] 質量分析計を使った膜タンパク質の定量方法2008

    • Inventor(s)
      上家潤一、大槻純男、寺崎哲也
    • Industrial Property Rights Holder
      国立大学法人東北大学
    • Filing Date
      2008-05-06
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] SWATH定量プロテオミクスに基づくヒト小児てんかんの焦点部位における血液脳関門と脳実質組織の病態変動機構の網羅的解明2020

    • Author(s)
      佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
    • Organizer
      日本薬学会 第140年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 定量プロテオミクスによるヒト血液クモ膜関門における薬物輸送担体及び薬物代謝酵素の発現量解析2020

    • Author(s)
      竹内妃奈、内田康雄、後藤諒平、臼井拓也、田野光敏、高尾昌樹、寺崎哲也
    • Organizer
      日本薬学会 第140年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Round Table Session 脳への薬物送達における 課題と解決法2019

    • Author(s)
      寺崎哲也
    • Organizer
      第34回日本薬剤学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] (英語口頭発表部門で優秀口頭発表賞を受賞(47演題中4演題)学部4年生が受賞するのは快挙) OCT2 protein is expressed in CSF side of the porcine blood-arachnoid barrier, while MATE1 is in blood side: Application of qTAP to transporter localization2019

    • Author(s)
      H Takeuchi, Y Uchida, R Goto, M Luczak, T Usui and T Terasaki
    • Organizer
      34th JSSX annual conference
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Proteomics based studies of disease effect on the blood-brain barrier transporters2019

    • Author(s)
      T Terasaki
    • Organizer
      12th International ISSX Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 脳関門プロテオミクスに基づく脳へのドラッグデリバリー2019

    • Author(s)
      寺崎哲也
    • Organizer
      第21回ヒューマンサイエンス総合研究ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 薬剤耐性型てんかん患者の血液脳関門で薬物代謝酵素が発現上昇する。2019

    • Author(s)
      佐藤理沙、内田康雄、大森広太郎、梅津美奈、Gerald Grant、Brenda Porter、Anthony Bet、立川正憲、臼井拓也、寺崎哲也
    • Organizer
      第58回日本薬学会東北支部大会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 基調講演 創薬科学の新地平:ペプチド検索エンジンを用いた定量的プロテオタイピング2019

    • Author(s)
      寺崎哲也
    • Organizer
      第10回記念Japan Bio Forum, JBFシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 定量プロテオミクスによるヒト血液脊髄関門における膜タンパク質の定量的発現プロファイルの解明2019

    • Author(s)
      八木悠太, 内田康雄, 梅津美奈, 平野誠巳, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Keynote Lecture, Regulation mechanism of P-gp in the blood-brain barrier2019

    • Author(s)
      T Terasaki
    • Organizer
      Meet the Experts 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 特別講演 定量的proteotypingに基づく薬剤学の新地平2019

    • Author(s)
      寺崎哲也
    • Organizer
      第34回日本薬剤学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] がんprecision medicineにおける次世代型網羅的標的プロテオミクス技術の応用2019

    • Author(s)
      寺崎哲也
    • Organizer
      ディ・スリー研究所設立20周年記念講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 膜タンパク質に対する網羅的なタンパク質絶対定量法 “QGAP 法 ” の開発:ヒト血液脳関門における網羅的な絶対発現量アトラス2019

    • Author(s)
      平野誠巳, 内田康雄, 梅津美奈, 後藤諒平, 八木悠太, 立川正憲, 田野光敏, 高尾昌樹, 寺崎哲也
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] (永井財団大学院学生スカラシップ採択) 網羅的かつ高精度なトランスポーター基質探索に向けたカクテル輸送実験におけるSWATH一斉定量法の評価2019

    • Author(s)
      笠森なな、内田康雄、寺崎哲也
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] ブタ血液クモ膜関門におけるトランスポーター13分子の局在一斉解明2019

    • Author(s)
      竹内妃奈、内田康雄、後藤諒平、Magdalena Luczak、臼井拓也、寺崎哲也
    • Organizer
      第58回日本薬学会東北支部大会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Transporter Mediated Drug Efflux at the BBB2019

    • Author(s)
      T Terasaki
    • Organizer
      2019 AAPS-IBBS Joint Workshop
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Anti-epileptic drug metabolizing enzymes are upregulated at the blood-brain barrier in pharmacoresistant childhood epilepsy: SWATH-based comprehensive quantitative proteomic study2019

    • Author(s)
      R Sato, Y Uchida, K Omori, M Umetsu, G Grant, B Porter, A Bet, M Tachikawa, T Usui, and T Terasaki
    • Organizer
      34th JSSX annual conference
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] (口頭発表部門で優秀発表賞を受賞) 脈絡叢と脳軟髄膜の標的プロテオミクス解析:ブタ1 頭あたりの脈絡叢と脳軟髄膜におけるトランスポータータンパク質の発現量解析と膜タンパク質の膜局在の網羅的解明2019

    • Author(s)
      後藤諒平、内田康雄、竹内妃奈、Magdalena Luczak、臼井拓也、立川正憲、寺崎哲也
    • Organizer
      第41回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Transporter Proteomics of the CNS Barriers2018

    • Author(s)
      Terasaki T
    • Organizer
      The 6th Asia Pacific Regional ISSX Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 特別講演:定量的Proteotypingに基づく創薬科学の新展開:脳関門輸送機構の解明と薬物送達を目指して2018

    • Author(s)
      寺崎哲也
    • Organizer
      日本薬学会北海道支部特別講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 多発性硬化症における中枢関門の破綻への新規密着結合分子claudin-11 の寄与の解明2018

    • Author(s)
      内田康雄, 住谷智仁, 立川正憲, 山川達也, 村田将, 八木悠太, 佐藤和貴, 伊藤克彰, 大槻純男, Pierre-Olivier Couraud, 鈴木貴, 寺崎哲也
    • Organizer
      日本薬剤学会第33 年会
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] Sulfo-SBED/SWATHプロテオミクスを用いたヒト血液脳関門モデルhCMEC/D3細胞におけるエクソソーム受容体の同定2018

    • Author(s)
      黒田広樹, 立川正憲, 八木悠太, 内田康雄, 寺崎哲也
    • Organizer
      第40回 生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Usefulness of Pressure Cycling Technology-assisted sample process for accurate and comprehensive quantitative proteomics using FFPE section; application for ADME-related proteins2018

    • Author(s)
      Sasaki H, Uchida Y, Tachikawa M, Terasaki T
    • Organizer
      第33回日本薬物動態学会・MDO国際合同年会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Quantitative targeted and global proteomics analysis of brain microvessels in pharmacoresistant epilepsy2018

    • Author(s)
      Omori K, Grant G, Tachikawa M, Porter B, Bet A, Uchida Y, Terasaki T
    • Organizer
      2018 Gordon Research Conference on Barriers of the CNS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 特別講演:生体膜輸送担体の定量的Proteotypingに基づく関門機能の解明2018

    • Author(s)
      寺崎哲也
    • Organizer
      第40回生体膜と薬物の相互作用シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 中枢関門の密着結合形成におけるclaudin-11の寄与と多発性硬化症におけるその発現低下の解明2018

    • Author(s)
      住谷智仁、内田康雄、山川達也、村田将、八木悠太、佐藤和貴、伊藤克彰、立川正憲、大槻純男、鈴木貴、寺崎哲也
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] New Horizon of Transporter Proteomics2018

    • Author(s)
      寺崎哲也
    • Organizer
      創薬動態フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 血液クモ膜関門を介した脳脊髄液中α-synuclein排出輸送機構の解明2018

    • Author(s)
      矢口優佳、立川正憲、内田康雄、寺崎哲也
    • Organizer
      第40回 生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Pressure Cycling Technologyを用いたホルマリン固定パラフィン包埋切片プロテオミクス定量系の薬物関連タンパク質への応用2018

    • Author(s)
      佐々木颯, 内田康雄, 立川正憲, 寺崎哲也
    • Organizer
      第40回 生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] ラット血液脊髄関門と血液脳関門におけるトランスポータータンパク質発現量の類似性と相違性の解明2018

    • Author(s)
      八木悠太、内田康雄、立川正憲、寺崎 哲也
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] ブタ脈絡叢と脳軟髄膜の網羅的・標的プロテオミクス解析:OATP1A2、OCT2及びMATE1の発現局在とCSF中薬物動態における役割2018

    • Author(s)
      後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Mechanism of Disease Effect on the Brain Barrier Transporter and Tight Junction Protein Analyzed by Proteomics2018

    • Author(s)
      Terasaki T
    • Organizer
      The 41st Annual Meeting of the Japan Neuroscience Society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 特別講演:脳関門の輸送機構と脳へのドラッグデリバリー:基礎から最先端まで2018

    • Author(s)
      寺崎哲也
    • Organizer
      第8回日本薬剤学会DDS製剤臨床応用フォーカスグループ合宿討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] SWATH及び高精度ペプチド選択を組み合わせた膜タンパク質のApical/Basolateral膜局在と絶対発現量の網羅的推定法の開発2018

    • Author(s)
      平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Sulfo-SBED/SWATH proteomics-based identification of RGD receptor integrins as the receptors for SK-Mel-28-derived exosomes internalization into human blood-brain barrier hCMEC/D3 cells2018

    • Author(s)
      Kuroda H, Tachikawa M, Uchida Y, Terasaki T
    • Organizer
      2018 Gordon Research Conference on Barriers of the CNS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Identification and absolute quantification of Transporters in the isolated human brain microvessels by next-generation quantitative proteomics SWATH-MS2018

    • Author(s)
      Umetsu M, Uchida Y, Hirano S, Takao M, Tachikawa M, Terasaki T
    • Organizer
      第33回日本薬物動態学会・MDO国際合同年会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Development of label free comprehensive absolute quantification method by SWATH-MS combined with in silico peptide selection criteria ~Its application for the hepatic drug delivery~2017

    • Author(s)
      平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
    • Organizer
      日本薬物動態学会第32回年会(優秀口頭発表賞受賞)
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] 脳転移性メラノーマ細胞由来exosomesによるヒト脳毛細血管内皮細胞株hCMEC/D3のエネルギー代謝抑制制御2017

    • Author(s)
      TRAN Quynh-Phuong、内田康雄、黒田広樹、梅津美奈、八木悠太、立川正憲、寺崎哲也
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] Development of label free comprehensive absolute quantification method by SWATH-MS combined with in silico peptide selection criteria : Its application for the hepatic drug delivery2017

    • Author(s)
      平野誠巳、内田康雄、立川正憲、後藤諒平、寺崎哲也
    • Organizer
      日本薬物動態学会第32回年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] Proteomics based characterization of the blood-spinal cord barrier transporters in rats: Comparison with the blood-brain barrier2017

    • Author(s)
      八木悠太、立川正憲、内田康雄、寺崎哲也
    • Organizer
      日本薬物動態学会第32回年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 標的定量質量分析法に基づくクモ膜上皮細胞と脈絡叢上皮細胞の有機アニオントランスポータータンパク質の解析:脳脊髄液中薬物動態における役割評価2017

    • Author(s)
      張正宇、立川正憲、内田康雄、寺崎哲也
    • Organizer
      第39回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] OUTER blood-CSF barrier (arachnoid membrane) abundantly expresses OAT1, OAT3, PEPT2 and BCRP proteins as compared to INNER blood-CSF barrier (choroid plexus)2017

    • Author(s)
      後藤諒平、内田康雄、立川正憲、平野誠巳、張正宇、寺崎哲也
    • Organizer
      日本薬物動態学会第32回年会
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] 中枢関門におけるandrogen刺激に応答したclaudin-11発現調節作用の解明と血液クモ膜関門におけるclaudin-11の発現解析2017

    • Author(s)
      住谷智仁、内田康雄、 山川達也、村田将、張正宇、立川正憲、大槻純男、寺崎哲也
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-24
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] Pharmacoproteomics (PPx) of the CNS Barriers: Recent Progress and Prospect2017

    • Author(s)
      Terasaki T
    • Organizer
      Allen J. Sedman Lecture Award in Pharmaceutical Sciences, University of Michigan, USA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04004
  • [Presentation] ブタBRB, BBB及びBCSFBの輸送担体の絶対発現量解析:BCRPの重要性2017

    • Author(s)
      張正宇、内田康雄、平野誠巳、安藤大介、久保義行、 Seppo Auriola、赤沼伸乙、立川正憲、細谷健一、Arto Urtti、寺崎哲也
    • Organizer
      日本薬剤学会第32年会 (最優秀発表賞受賞)
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] Proteomics based characterization of the blood-spinal cord barrier transporters in rats: Comparison with the blood-brain barrier2017

    • Author(s)
      八木悠太、立川正憲、内田康雄、寺崎哲也
    • Organizer
      日本薬物動態学会第32回年会
    • Data Source
      KAKENHI-PROJECT-16K15475
  • [Presentation] クレアチン脳欠乏症治療を指向したカチオン性アミノ酸トランスポーターを輸送経路とするクレアチンプロドラッグの開発2017

    • Author(s)
      太田悠介、立川正憲、吉田将人、土井隆行、和田敬仁、寺崎 哲也
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2017-03-27
    • Data Source
      KAKENHI-PROJECT-16K15153
  • [Presentation] Abl及びSrc kinasesによる血液脳関門P-glycoproteinの細胞内トラフィッキング制御機構の解明2016

    • Author(s)
      星 裕太朗、内田 康雄、立川 正憲、大槻 純男、寺崎 哲也
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Biomarkers of glioblastoma identified by quantitative proteomics with SWATH mass spectrometry2016

    • Author(s)
      Nakada M, Miyauchi E, Tachikawa M, Furuta T, Sabit H, Ohtsuki S, Terasaki T.
    • Organizer
      The 21st International Conference on Brain Tumor Research & Therapy
    • Place of Presentation
      Okinawa, Bankoku Shinryokan
    • Year and Date
      2016-04-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15645
  • [Presentation] Biomarkers of glioblastoma identified by quantitative proteomics with SWATH mass spectrometry.2016

    • Author(s)
      Nakada M, Miyauchi E, Tachikawa M, Furuta T, Sabit H, Ohtsuki S, Terasaki T.
    • Organizer
      The 21st International Conference on Brain Tumor Research & Therapy
    • Place of Presentation
      Bankoku Shinryokan (Okinawa)
    • Year and Date
      2016-04-10
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670638
  • [Presentation] Quantitative Targeted Proteomics for ADME Predictions.2016

    • Author(s)
      Terasaki T.
    • Organizer
      Symposium on Pharmaceutical Profiling in Drug Discovery and Development
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2016-01-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 最先端プロテオミクスSWATH法による膠芽腫バイオマーカーの探索2015

    • Author(s)
      中田光俊,宮内英輔、立川正憲、古田拓也、淑瑠ヘムラサビット,大槻純男、寺崎哲也
    • Organizer
      第16回日本分子脳神経外科学会
    • Place of Presentation
      アクトシティ浜松コングレスセンター(浜松)
    • Year and Date
      2015-08-28
    • Data Source
      KAKENHI-PROJECT-26670638
  • [Presentation] 標的プロテオミクスに基づくタンパク質リン酸化修飾の定量的解析2015

    • Author(s)
      星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
    • Organizer
      日本プロテオーム学会2015年会
    • Place of Presentation
      熊本
    • Year and Date
      2015-07-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Post-translational regulation of P-glycoprotein function at the blood-brain barrier involved in caveolin-1 tyrosine 14 phosphorylation.2015

    • Author(s)
      Hoshi Y, Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T.
    • Organizer
      30th JSSX Annual Meeting
    • Place of Presentation
      東京
    • Year and Date
      2015-11-12
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 血液脳関門ファーマコプロテオミクスに立脚した中枢疾患創薬の提言2015

    • Author(s)
      立川正憲、内田康雄、大槻純男、寺崎哲也
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 血液脳関門の生理的役割と脳への薬物移行2015

    • Author(s)
      寺崎哲也
    • Organizer
      第19回日本神経麻酔集中治療学会
    • Place of Presentation
      岐阜
    • Year and Date
      2015-04-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Impact of quantitative proteomics on the blood-brain barrier transport research.2015

    • Author(s)
      Terasaki T.
    • Organizer
      11th International Conference on Cerebral Vascular Biology
    • Place of Presentation
      Paris, France
    • Year and Date
      2015-07-06
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Global and Quantitative Targeted Phosphoproteomic Studies on the Blood-Brain Barrier P-gp Regulation Mechanism in Acute Phase Diseased Models.2015

    • Author(s)
      Hoshi Y, Uchida Y, Kuroda T, Tachikawa T, Terasaki T
    • Organizer
      BioMed Conference, Blood Brain Barrier
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2015-11-02
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] リン酸化定量プロテオミクスに基づく血液脳関門P-glycoproteinの輸送活性制御機構の解明2015

    • Author(s)
      星裕太朗、内田康雄、立川正憲、大槻純男、寺崎哲也
    • Organizer
      第10回トランスポーター研究会年会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-20
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 前処理自動化と質量分析を組み合わせたハイスループットMRM法の開発2014

    • Author(s)
      米山敏広、大槻純男、尾野雅哉、大峰健、内田康雄、立川正憲、寺崎哲也
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 開口スイッチの導入によるpannexin1及びconnexin32機能解析系の構築と輸送特性の解明2014

    • Author(s)
      赤荻諒、立川正憲、金子洋介、内田康雄、寺崎哲也
    • Organizer
      第53回日本薬学会東北支部大会
    • Place of Presentation
      いわき
    • Year and Date
      2014-10-05
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 標的定量プロテオミクス解析に基づく病態時血液脳関門輸送系の可塑的変化の解明2014

    • Author(s)
      立川正憲、星裕太朗、佐藤和貴、内田康雄、大槻純男、寺崎哲也
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-07-31
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 標的絶対定量プロテオミクスに基づくがん分子標的化学療法の個別・層別化基盤の構築2014

    • Author(s)
      内田康雄、立川正憲、小渕航、大槻純男、中田光俊、濱田潤一郎、寺崎哲也
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] マウス炎症性疾患モデルを用いた脳毛細血管における接着分子の標的定量プロテオミクス解析2014

    • Author(s)
      佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
    • Organizer
      第22回クリニカルファーマシーシンポジウム 医療薬学フォーラム2014
    • Place of Presentation
      東京
    • Year and Date
      2014-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 血液脳関門—白血球細胞遊走に関わる接着分子の標的定量プロテオミクス解析2014

    • Author(s)
      佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-29
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 定量的標的絶対プロテオミクスに基づく癌化学療法の新展開2013

    • Author(s)
      寺崎哲也
    • Organizer
      公益社団法人・日本薬剤学会主催APSTJ WG 2025シンポジウム「バイオとナノが拓く医療イノベーション」
    • Place of Presentation
      東京
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 膜タンパク質を標的とした定量的標的プロテオミクスに基づく悪性脳腫瘍に対する個別化分子標的療法2013

    • Author(s)
      小渕航、大槻純男、中田光俊、内田康雄、立川正憲、濱田潤一郎、寺崎哲也
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋
    • Year and Date
      2013-05-23
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Quantitative Targeted Absolute Proteomics (QTAP): The Impact on the Research of Blood-Brain Barrier Structure and Function2013

    • Author(s)
      Terasaki T
    • Organizer
      The workshop "Beating the Blood-Brain and other blood barriers"
    • Place of Presentation
      Lisbon, Portugal
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Quantitative targeted absolute proteomics of the malignant brain tumors towards molecular-targeted chemotherapy2013

    • Author(s)
      Terasaki T, Obuchi W, Ohtsuki S, Nakada M, Uchida Y, Tachikawa M, Hamada J
    • Organizer
      10th International Society for the Study of Xenobiotics (ISSX) Meeting
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2013-09-30
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Pharmacoproteomics : 定量的標的絶対プロテオミクスに基づく薬剤学の新展開2013

    • Author(s)
      寺崎哲也
    • Organizer
      薬剤学教科担当教員会議
    • Place of Presentation
      富山
    • Year and Date
      2013-08-30
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 仮想selective reaction monitoring法を用いた白血球細胞膜上タンパク質の高感度標的プロテオミクス2013

    • Author(s)
      佐藤和貴、立川正憲、内田康雄、大槻純男、寺崎哲也
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Quantitative targeted absolute proteomics of the malignant brain tumors towards molecular-targeted chemotherapy.2013

    • Author(s)
      Terasaki T., Obuchi W., Ohtsuki S.,Nakada M., Uchida Y., Tachikawa M., Hamada J.
    • Organizer
      10th International ISSX Meeting
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 膵癌細胞のゲムシタビン感受性増強を目的とした併用薬のスクリーニング2013

    • Author(s)
      黒田広樹、立川正憲、内田康雄、寺崎哲也
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      横浜
    • Year and Date
      2013-03-28
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Pharmacoproteomics : Quantitative Targeted Absolute Proteomics (QTAP) based Pharmacokinetics as A New Path to the Drug Discovery and Development and the Personalized Medicine2013

    • Author(s)
      Terasaki T
    • Organizer
      International Symposium for the retirement of Professor Chang Koo Shim
    • Place of Presentation
      Seoul National University, Seoul, South Korea
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Molecular mechanisms of drug influx and efflux transport at the blood-brain barrier2012

    • Author(s)
      Terasaki T
    • Organizer
      Multiple Drug Abuse and Medicines: U-FOLD at Uppsala University Conference
    • Place of Presentation
      Uppsala, Sweden
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Pharmacoproteomics as a Quantitative Targeted Absolute Proteomics (QTAP) based Pharmacokinetics: A New Strategy for the Prediction of Small Intestinal Absorption, Hepatic Elimination and Brain Distribution, Short Course “LC-MS/MS Based Targeted Quantification of Membrane Proteins”2012

    • Author(s)
      Terasaki T
    • Organizer
      2012 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Chicago, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics (PPx): Challenge for the Discovery of New Barrier Function in human2012

    • Author(s)
      Terasaki T
    • Organizer
      Barriers of the CNS Gordon Research Conference
    • Place of Presentation
      Colby Sawyer College, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Targeted quantitative LC-MS/MS methods of bevacizumab, a therapeutic monoclonal antibody2012

    • Author(s)
      Ebata Y, Ohtsuki S, Tachikawa M, Uchida Y, Terasaki T
    • Organizer
      日本薬物動態学会第27年会
    • Place of Presentation
      千葉
    • Year and Date
      2012-11-21
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Quantitative Targeted Absolute Proteomics of BBB Transporters : Changes with Species and Disease2011

    • Author(s)
      T. Terasaki
    • Organizer
      SESSION 10 : DRUG TRANSPORTERS AND CNS PENETRATION
    • Place of Presentation
      Bethesda, Maryland, USA
    • Year and Date
      2011-03-16
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative Targeted Absolute Proteomics of BBB Transporters : Changes with Species and Disease2011

    • Author(s)
      Terasaki T
    • Organizer
      American Association of Pharmaceutical Scientist, Workshop
    • Place of Presentation
      Bethesda, Maryland, USA
    • Year and Date
      2011-03-16
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 機能性蛋白質の絶対発現量解析法を用いた血液脳関門及び脳腫瘍の病態変動解明:個別診断法の開発を目指して2011

    • Author(s)
      寺崎哲也
    • Organizer
      第4回金沢脳腫瘍セミナー
    • Place of Presentation
      金沢
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 血液脳関門ファーマコプロテオミクス:血液脳関門輸送に基づく薬物の脳移行性の再構築と動物種差、病態解析への応用2010

    • Author(s)
      寺崎哲也
    • Organizer
      Pharmacokinetics for Parkinson Disease Conference 2010
    • Place of Presentation
      東京
    • Year and Date
      2010-07-24
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantification of Transporter/Enzyme Protein in Human Tissue by Mass Spectrometry : A New Path to Pharmacoproteomics (PPx)2010

    • Author(s)
      T. Terasaki, S. Ohtsuki
    • Organizer
      9th International ISSX meeting, Symposium 3 : Clinical Pharmacology of Drug Transport : From Bench to Bedside
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2010-09-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative protein analysis of human glioblastoma2010

    • Author(s)
      T.Terasaki, M.Nakada, C.Ikeda, Y.Hayashi, J.Hamada, Y.Sonoda, T.Kumabe, T.Tominaga, S.Ohtsuki
    • Organizer
      Neoangiogenesis in Brain Tumours, International meeting of Signal Transduction of the Blood-Brain Barrier, Zurich 2010
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 標的絶対プロテオミクスに基づくヒト細胞特性評価とその創薬研究への応用を目指して2010

    • Author(s)
      寺崎哲也
    • Organizer
      2010年度薬物動態談話会特別例会
    • Place of Presentation
      浜松
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Development of highly sensitive simultaneous protein quantification by LC-MS/MS and its application for the research of human disease2010

    • Author(s)
      T. Terasaki, S. Ohtsuki
    • Organizer
      28th The Japan Endocrine Society (JES)Summer Seminar on Endocrinology & Metabolism (Toward the Progress and Development of Endocrinology, Session 1 : Advancement of Research Technologies)
    • Place of Presentation
      Huis Ten Bosch, Nagasaki
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 標的絶対プロテオミクスに基づくヒト肝細胞特性評価とその創薬応用を目指して2010

    • Author(s)
      寺崎哲也
    • Organizer
      日本製薬工業会セミナー(iPS細胞由来ヒト肝細胞の創薬応用)
    • Place of Presentation
      東京
    • Year and Date
      2010-07-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics : Quantitative Transporter Protein Analysis for In Vitro-In Vivo, Interspecies and Diseased State Differences . Transporter Proteins III : Clinical Relevance and Applications, Session 392, Convention Center, New Orleans2010

    • Author(s)
      T. Terasaki
    • Organizer
      24th Annual Meeting of American Association of Pharmaceutical Scientists
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Pharmacoproteomics:質量分析装置を用いたヒト組織機能性タンパク質の絶対定量値に基づく薬効副作用予測2010

    • Author(s)
      寺崎哲也
    • Organizer
      第17回HAB(Human and Animal Bridge)研究機構学術年会(創薬とヒト組織利用-薬効と副作用予測への挑戦-『細胞工学からのメッセージ』シンポジウムI薬効予測とヒト組織利用)
    • Place of Presentation
      東京
    • Year and Date
      2010-05-21
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantification of Transporter/Enzyme Protein in Human Tissue by Mass Spectrometry : A New Path to Pharmacoproteomics (PPx)2010

    • Author(s)
      T.Terasaki, S.Ohtsuki
    • Organizer
      9th International ISSX meeting
    • Place of Presentation
      Istanbul, Turkey
    • Year and Date
      2010-09-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics : Quantitative Transporter Protein Analysis for In Vitro-In Vivo, Interspecies and Diseased State Differences2010

    • Author(s)
      Terasaki T
    • Organizer
      24^<th> Annual Meeting of American Association of Pharmaceutical Scientists
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Development of highly sensitive simultaneous protein quantification by LC-MS/MS and its application for the research of human disease2010

    • Author(s)
      T.Terasaki, S.Ohtsuki
    • Organizer
      28th The Japan Endocrine Society (JES) Summer Seminar on Endocrinology & Metabolism (Toward the Progress and Development of Endocrinology
    • Place of Presentation
      Nagasaki
    • Year and Date
      2010-07-08
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative protein analysis of human glioblastoma, Neoangiogenesis in Brain Tumours2010

    • Author(s)
      T. Terasaki, M. Nakada, C. Ikeda, Y. Hayashi, J. Hamada, Y. Sonoda, T. Kumabe, T. Tominaga, S. Ohtsuki
    • Organizer
      International meeting of Signal Transduction of the Blood-Brain Barrier, Zurich 2010, Symposium 9
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 標的絶対プロテオミクスに基づいた血液脳関門の動物種差と病態変動の分子機構2010

    • Author(s)
      寺崎哲也
    • Organizer
      金沢大学大学院医学系研究科脳・脊髄機能制御学(脳神経外科学)セミナー
    • Place of Presentation
      金沢
    • Year and Date
      2010-05-28
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] New approach to drug design by quantitative membrane proteomics2009

    • Author(s)
      大槻純男, 寺崎哲也
    • Organizer
      Special lecture in Seoul Netional University
    • Place of Presentation
      Seoul
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Protein expression profile of membrane transporters in the capillaries of normal human brain by lc-ms/ms based quantification2009

    • Author(s)
      Y.Katsukura, T.Terasaki
    • Organizer
      Global COE Network Medicine The 1st International Symposium-Challenge to Medical Innovation-
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Quantitative Targeted Absolute Proteomics(QTAP)based Pharmacokinetics as a New Path for the Drug Discovery and Development2009

    • Author(s)
      寺崎哲也
    • Organizer
      Asian Federation for Pharmacutical Sciences 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 質量分析装置を用いたトランスポータータンパク質の絶対定量と in vivo 機能の再構築2009

    • Author(s)
      寺崎哲也
    • Organizer
      第82回生化学会大会 シンポジウム「トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して」
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 創薬研究の新地平:血液脳関門ファーマコプロテオミクス2009

    • Author(s)
      寺崎哲也
    • Organizer
      東北大学バイオフォーラム(産学官連携の展開を図るため)、脳科学の革新的発展を目指して、東京ステーションカンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Alteration of transporter protein expressions and in vitro-to-in vivo re-construction of p-glycoprotein function at the blood-brain barrier in mouse model of epilepsy and phenytoin therapy2009

    • Author(s)
      内田康雄, 寺崎哲也
    • Organizer
      Global COE Network Medicine The 1st International Symposium-Challenge to Medical Innovation-
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics as a novel method for the prediction of drug delivery to the brain2009

    • Author(s)
      T. Terasaki, Y. Uchida, H. Kawakami, Y. Katsukura, J. Kamiie, S. Ohtsuki
    • Organizer
      7th Retrometabolism Based Drug Design and Targeting Conference
    • Place of Presentation
      Orlando, Florida, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics as a novel method for the prediction of drug delivery to the brain2009

    • Author(s)
      寺崎哲也
    • Organizer
      7th Retrometabolism Based Drug Design and Targeting Conference
    • Place of Presentation
      Florida, USA
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Pharmacoproteomics:タンパク質の高感度絶対定量法を用いた創薬研究の新地平2009

    • Author(s)
      寺崎哲也
    • Organizer
      医薬基盤研究所セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Transporter protein qunatification for the future of thransporter science. Advanced Technologies for the Future of Transporter Sciences2009

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      The 36th Congress of the International Union of Physiological Sciences (IUPS2009)
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 新薬開発のボトルネック解消を目指した解収束型プロテオミクスの新展開:高感度多検体同時普遍的タンパク質絶対定量法を用いたファーマコプロテオミクス、S2タンパク質研究から医薬品開発への道2009

    • Author(s)
      寺崎哲也
    • Organizer
      日本ヒトプロテオーム機構第7回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Quantitative Targeted Absolute Proteomics(QTAP)を用いたトランスポーター研究のPK-PDへの応用、Transporter Symposiumトランスポーター研究の新たな展開2009

    • Author(s)
      寺崎哲也
    • Organizer
      トランスポーターを標的とした創薬への動向、トランスポーター研究会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] PHARMACOPROTEOMICS(PPX): QUANTITATIVE TARGETED ABSOLUTE PROTEOMICS(QTAP)BASED PHARMACO KINETICS, PHARMACODYNAMICS AND TOXICOKINETICS2009

    • Author(s)
      寺崎哲也
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Transporter protein qunatification for the future of thransporter science2009

    • Author(s)
      寺崎哲也
    • Organizer
      Advanced Technologies for the Future of Transporter Sciences, The 36th Congress of the International Union of Physiological Sciences
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Quantitative Targeted Absolute Proteomics(QTAP)を用いたトランスポーター研究のPK-PDへの応用、Transporter Symposium トランスポーター研究の新たな展開2009

    • Author(s)
      寺崎哲也
    • Organizer
      トランスポーターを標的とした創薬への動向、トランスポーター研究会
    • Place of Presentation
      神戸
    • Year and Date
      2009-06-02
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 副腎皮質ステロイド薬が血液脳関門に及ぼす影響の解析2009

    • Author(s)
      柏村陽子, 寺崎哲也, 神田隆
    • Organizer
      第20回日本末梢神経学会学術集会
    • Place of Presentation
      大宮,大宮ソニックシティ
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Transporter protein quantification for the future of transporter science. Advanced Technologies for the Future of Transporter Sciences2009

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      36th Congress of the International Union of Physiological Sciences
    • Place of Presentation
      Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Prediction of In Vivo ADME Based on the Transporter Protein Quantification.2009

    • Author(s)
      T. Terasaki
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels, CA, USA
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics as a novel method for the prediction of drug delivery to the brain2009

    • Author(s)
      寺崎哲也
    • Organizer
      7th Retrometabolism Based Drug Design and Targeting Conference
    • Place of Presentation
      Florida(USA)
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] ファーマコプロテオミクスを基盤とする新しい薬物動態研究2009

    • Author(s)
      大槻純男, 寺崎哲也
    • Organizer
      第13回薬物動態談話会セミナー
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] ヒト脳微小血管内皮細胞の安定細胞株の樹立2009

    • Author(s)
      柏村陽子, 寺崎哲也, 神田隆
    • Organizer
      第112回山口大学医学会学術講演会
    • Place of Presentation
      宇部,山口大学霜仁会館
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Quantitative targeted absolute proteomics(QTAP)for the tumor drug resistance2009

    • Author(s)
      寺崎哲也
    • Organizer
      Global COE Network Medicine The 1st International Symposium-Challenge to Medical Innovation-
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative Targeted Absolute Proteomics(QTAP)based Pharmacokinetics as a New Path for the Drug Discovery and Development2009

    • Author(s)
      寺崎哲也
    • Organizer
      Asian Federation for Pharmacutical Sciences 2009
    • Place of Presentation
      Fukuoka
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Pharmacoproteomics:タンパク質の高感度絶対定量法を用いた創薬研究の新地平2009

    • Author(s)
      寺崎哲也
    • Organizer
      医薬基盤研究所セミナー
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 22th Biennal Meeting of the International Society for Neurochemistry (ISN)2009

    • Author(s)
      T. Terasaki
    • Organizer
      American Society Neurochemistry Joint Meeting
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] In vitro-to-in vivo re-construction of blood-brain barrier penetration integrating P-glycoprotein absolute expression, its in vitro activity, and free fractions in plasma and brain2009

    • Author(s)
      内田康雄, 寺崎哲也
    • Organizer
      8th Cerebral Vascular International Conference
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pericyte forming blood-brain and blood-nerve barriers express tight junctional molecules and transporters as barrier-forming cells2009

    • Author(s)
      Shimizu F, Terasaki T, Kanda T
    • Organizer
      8th Cerebral Vascular Biology International Conference
    • Place of Presentation
      Sendai, Excel Hotel Sendai
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Conditionally immortalized cell line of rat choroid plexus epithelial cell(TR-CSFB)as an useful in vitro model for the blood-cerebrospinal fluid barrier.2009

    • Author(s)
      寺崎哲也
    • Organizer
      22th Biennal Meeting of the International Society for Neurochemistry(ISN), American Society Neurochemistry Joint Meeting
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 質量分析装置を用いたトランスポータータンパク質の絶対定量とin vivo機能の再構築2009

    • Author(s)
      寺崎哲也
    • Organizer
      第82回生化学会大会 シンポジウム「トランスポーター研究のパラダイムシフト:ヒトシステムの理解を目指して」
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 創薬研究の新地平:血液脳関門ファーマコプロテオミクス2009

    • Author(s)
      寺崎哲也
    • Organizer
      東北大学バイオフォーラム(産学官連携の展開を図るため)、脳科学の革新的発展を目指して、東京ステーションカンファレンス
    • Place of Presentation
      東京
    • Year and Date
      2009-06-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 新薬開発のボトルネック解消を目指した解収束型プロテオミクスの新展開:高感度多検体同時普遍的タンパク質絶対定量法を用いたファーマコプロテオミクス、S2タンパク質研究から医薬品開発への道2009

    • Author(s)
      寺崎哲也
    • Organizer
      日本ヒトプロテオーム機構第7回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-07-27
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Alteration of protein expression profile of transporters and the in vitro-to-in vivo re-construction of P-gp function at the blood-brain barrier in mouse model of epilepsy2009

    • Author(s)
      内田康雄, 寺崎哲也
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels(USA)
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] In vitro-to-in vivo re-construction of brain distribution for P-glycoprotein substrates in mouse and monkey based on its absolute expression, intrinsic transport activity, and unbound fraction in plasma and brain2009

    • Author(s)
      内田康雄、寺崎哲也
    • Organizer
      第31回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Prediction of In Vivo ADME Based on the Transporter Protein Quantification2009

    • Author(s)
      寺崎哲也
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels(USA)
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] ファーマコプロテオミクス解析によるガン薬剤耐性機構の解明2009

    • Author(s)
      大槻純男, 寺崎哲也
    • Organizer
      日本医療薬学会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Transporter protein qunatification for the future of thransporter science2009

    • Author(s)
      寺崎哲也
    • Organizer
      Advanced Technologies for the Future of Transporter Sciences, The 36th Congress of the International Union of Physiological Sciences
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative protein expression profiles of membrane transporters at isolated human brain capillaries2009

    • Author(s)
      内田康雄, 寺崎哲也
    • Organizer
      8th Cerebral Vascular International Conference
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Conditionally immortalized cell line of rat choroid plexus epithelial cell(TR-CSFB)as an useful in vitro model for the blood-cerebrospinal fluid barrier2009

    • Author(s)
      寺崎哲也
    • Organizer
      22th Biennal Meeting of the International Society for Neurochemistry(ISN), American Society Neurochemistry Joint Meeting
    • Place of Presentation
      Busan(韓国)
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] QUANTITATIVE TARGETED ABSOLUTE PROTEOMICS(QTAP)FOR MEMBRANE TRANSPORTERS AT HUMAN BLOOD-BRAIN BARRIERS2009

    • Author(s)
      内田康雄、寺崎哲也
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Prediction of In Vivo ADME Based on the Transporter Protein Quantification2009

    • Author(s)
      T. Terasaki
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels, CA, USA
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Prediction of In Vivo ADME Based on the Transporter Protein Quantification2009

    • Author(s)
      寺崎哲也
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels, USA
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative transporter protein analysis of human brain capillary endothelial2009

    • Author(s)
      寺崎哲也
    • Organizer
      8th Cerebral Vascular Biology International Conference
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] PHARMACOPROTEOMICS(PPX) : QUANTITATIVE TARGET ED ABSOLUTE PROTEOMICS(QTAP)BASED PHARMACO KINETICS, PHARMACODYNAMICS AND TOXICOKINETICS2009

    • Author(s)
      寺崎哲也
    • Organizer
      日本薬物動態学会第24回年会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] ファーマコプロテオミクス解析によるガン薬剤耐性機構の解明2009

    • Author(s)
      大槻純男, 寺崎哲也
    • Organizer
      日本薬剤学会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] アミロイドトランスポーターの発現に及ぼすエストロゲンの影響2009

    • Author(s)
      前田敏彦, 寺崎哲也, 神田隆
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台,仙台国際センター
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] AGEが血液神経関門に及ぼす影響の解析2009

    • Author(s)
      清水文崇, 寺崎哲也, 神田隆
    • Organizer
      第20回日本末梢神経学会学術集会
    • Place of Presentation
      大宮,大宮ソニックシティ
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Expression profile of membrane transporter proteins at isolated human brain capillaries by targeted absolute proteomics2009

    • Author(s)
      内田康雄, 寺崎哲也
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels(USA)
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Establishment and characterization of a stable immortalized human brain microvascular endothelial cell line2009

    • Author(s)
      Kashiwamura Y, Terasaki T, Kanda T
    • Organizer
      8th Cerebral Vascular Biology International Conference
    • Place of Presentation
      Sendai, Excel Hotel Sendai
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] The comparison of absolute expression profiles of membrane proteins between immortalized human cerebral microvascular endothelial cells(hCMEC/D3)and isolated human brain capillaries2009

    • Author(s)
      C.Ikeda, T.Terasaki
    • Organizer
      8th Cerebral Vascular International Conference
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Quantitative targeted absolute proteomics(QTAP)for the tumor drug resistance2009

    • Author(s)
      寺崎哲也
    • Organizer
      Global COE Network Medicine The 1st International Symposium-Challenge to Medical Innovation-
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] ヒト脳微小血管内皮細胞の安定細胞株の樹立2009

    • Author(s)
      柏村陽子, 寺崎哲也, 神田隆
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台,仙台国際センター
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Pharmacoproteomics (PPx): Quantitative Targeted Absolute Proteomics (QTAP) based Pharmacokinetics as a New Path for the Drug Discovery and Development2009

    • Author(s)
      T. Terasaki
    • Organizer
      Asian Federation for Pharmacutical Sciences 2009
    • Place of Presentation
      Fukuoka, Japan
    • Year and Date
      2009-10-16
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics in Cancer Research2009

    • Author(s)
      大槻純男, 寺崎哲也
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels, USA
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative transporter protein analysis of human brain capillary endothelial2009

    • Author(s)
      T. Terasaki
    • Organizer
      8the Cerebral Vascular Biology International Conference (CVB2009)
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Quantitative transporter protein analysis of human brain capillary endothelial2009

    • Author(s)
      T. Terasaki
    • Organizer
      8the Cerebral Vascular Biology International Conference (CVB2009)
    • Place of Presentation
      Sendai, Japan
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Quantitative transporter protein analysis of human brain capillary endothelial2009

    • Author(s)
      寺崎哲也
    • Organizer
      8th Cerebral Vascular International Conference
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 高血糖が血液神経関門に及ぼす影響2009

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台,仙台国際センター
    • Data Source
      KAKENHI-PROJECT-21390268
  • [Presentation] Targeted absolute proteomics analysis of localization of transporters in mouse liver using LC-MS/MS2008

    • Author(s)
      T. Terasaki
    • Organizer
      2008 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 最近の薬剤学 : Pharmacoproteomics : Targeted Absolute Proteomicsに基づく薬剤学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      平成20年度国公私立大学病院薬剤部職員研修会、主催 : 文部科学省後援
    • Place of Presentation
      東京大学医学部附属病院
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Pharmacoproteomics in Cancer Research2008

    • Author(s)
      S. Ohtsuki, R. Iwase, J. Kamiie, K. Ohmine, H. Harigae, T. Terasaki
    • Organizer
      2009 AAPS Annual Meeting and Exposition
    • Place of Presentation
      Los Angels, CA, USA
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 動的インターフェースとしての血液脳関門の分子機構2008

    • Author(s)
      寺崎哲也
    • Organizer
      第23回新潟腎シンポジウム
    • Place of Presentation
      新潟市・有壬記念館
    • Year and Date
      2008-08-02
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics : Targeted Absolute Proteomicsに基づく薬剤学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      Frontier's Nanomedicine-Summer Workshop 2008-、(主催 : 日本薬学会北海道支部会、共催 : 日本生化学会北海道支部、北海道分子生物学研究会)
    • Place of Presentation
      札幌、北海道大学大学院薬学研究院
    • Year and Date
      2008-08-05
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Biomedical Sciences2008

    • Author(s)
      T. Terasaki
    • Organizer
      Leibniz-Institut of Molekulare Pharmakologie (FMP)
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-04-14
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] A new conditionally immortalized human brain microvascular endothelial cell line2008

    • Author(s)
      Sano Y, Terasaki T, Kanda T
    • Organizer
      American Neurological association 133rd Annual Meeting Salt Lake City
    • Place of Presentation
      Utah, USA
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Targeted absolute proteomics as a new path to the drug discovery and development2008

    • Author(s)
      T. Terasaki
    • Organizer
      Winter Symposium of Research Triangle Park -Drug Metabolizing Discussion Group (RTP-DMDG)
    • Place of Presentation
      Chapel Hill, North Carolina, USA
    • Year and Date
      2008-03-05
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics (PPx) : Targeted absolute proteomics-based pharmacokinetics as a new path for the blood-brain barrier research2008

    • Author(s)
      T. Terasaki
    • Organizer
      BLOOD-BRAIN BARRIER CONSORTIUM CLUB Symposium : The impact of efflux transports on CNS drug distribution
    • Place of Presentation
      London, United Kingdo
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 血液脳関門トランスポートソームの生理的役割2008

    • Author(s)
      寺崎哲也
    • Organizer
      特定領域研究「生体膜トランスポートソームの分子機構と生理機能』平成20年度第1回班会議
    • Place of Presentation
      淡路島
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Biomedi cal Sciences2008

    • Author(s)
      T. Terasaki
    • Organizer
      Leibniz-Institut of Molekulare Pharmakolo gie (FMP)
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-04-14
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Pharmaceutical and Biomedical Sciences both for Academia and Industry2008

    • Author(s)
      T. Terasaki
    • Organizer
      Special Seminar at the University Paris 5, Faculty of Pharmaceutical Sciences
    • Place of Presentation
      Paris, France
    • Year and Date
      2008-04-21
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Targeted Absolute Proteomicsを用いた創薬科学と薬物治療学への新たな挑戦2008

    • Author(s)
      寺崎哲也
    • Organizer
      日本薬剤学会第23年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absoiute Proteomicsを用いた創薬科学と薬物治療学への新たな挑戦2008

    • Author(s)
      寺崎哲也
    • Organizer
      日本薬剤学会第23年会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Pharmaceutical and Biomedical Sciences both for Academia and Industry2008

    • Author(s)
      T. Terasaki
    • Organizer
      Special Seminar at the University Paris 5, Faculty of Pharmaceutical Sciences
    • Place of Presentation
      Paris, France 14.
    • Year and Date
      2008-04-21
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Pharmacoproteomics : Targeted Absolute Proteomlcsに基づく薬剤学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      成20年度国公私立大学病院薬剤部職員研修会、(文部科学省後援)
    • Place of Presentation
      東京大学医学部附属病院中央診療棟
    • Year and Date
      2008-05-30
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Pharmaceutical and Biomedical Sciences both for Academia and Industry2008

    • Author(s)
      T. Terasaki
    • Organizer
      Special Seminar at the University Paris 5, Faculty of Pharmaceutical Sciences
    • Place of Presentation
      Paris, France
    • Year and Date
      2008-04-21
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted Absolute Proteomics as A New Path to the Biomedical Sciences2008

    • Author(s)
      T. Terasaki
    • Organizer
      Leibniz-Institut of Molekulare Pharmakologie (FMP)
    • Place of Presentation
      Berlin, Germany
    • Year and Date
      2008-04-14
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Blood-brain barrier and blood-cerebrospinal fluid barrier transport of amyloid beta peptide2008

    • Author(s)
      T. Terasaki
    • Organizer
      International Symposium on Biologically Active Peptides : Peptide Diversity
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2008-08-31
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 三連四重極型質量分析装置を用いた癌薬剤耐性関連蛋白質の絶対発現量解析2008

    • Author(s)
      寺崎哲也
    • Organizer
      第67回日本癌学会総会ランチョンセミナー
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 血液脳関門(BBB)及び血液神経関門(BNB)におけるペリサイトの役割2008

    • Author(s)
      柏村陽子, 神田隆, 寺崎哲也
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Targeted Absolute Proteomicsに基づく創薬科学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      ヒューマンサイエンス振興財団情報委員会、(主催 : ヒューマンサイエンス振興財団)
    • Place of Presentation
      東京
    • Year and Date
      2008-04-10
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics (PPx) : Targeted absolute proteomics-based pharmacokinetics as a new path for the blood-brain barrier research2008

    • Author(s)
      T. Terasaki
    • Organizer
      BLOOD-BRAIN BARRIER CONSORTIUM CLUB Symposium : 'The impact of efflux transports on CNS drug distribution'
    • Place of Presentation
      London, United Kingdom
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] Pharmacoproteomics : Targeted Absolute Proteomicsに基づく薬剤学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      Frontie's Nanomedicine-Summer Workshop2008、日本薬学会北海道支部会、共催 : 日本生化学会北海道支部、北海道分子生物学研究会
    • Place of Presentation
      北海道大学大学院薬学研究科
    • Year and Date
      2008-08-05
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] argeted Absolute Proteomicsに基づく創薬科学の新展開2008

    • Author(s)
      寺崎哲也
    • Organizer
      1ヒューマンサイエンス振興財団情報委員会
    • Place of Presentation
      東京
    • Year and Date
      2008-04-10
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] 動的インターフェースとしての血液脳関門の分子機構2008

    • Author(s)
      寺崎哲也
    • Organizer
      第23回新潟腎シンポジウム
    • Place of Presentation
      新潟市・有壬記念館
    • Year and Date
      2008-08-02
    • Data Source
      KAKENHI-PROJECT-18109002
  • [Presentation] ヒト由来のBBB とBNB を構成するペリサイトの細胞学的相異の検討2008

    • Author(s)
      清水文崇, 寺崎哲也, 神田隆
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ヒト神経内膜内微小血管内皮細胞(HPnMECs)のcell line の作成2008

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第49回日本神経学会総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ヒト血液神経関門 in vitro モデルの確立2008

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第19回日本末梢神経学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-05
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ヒト神経内膜内微小血管内皮細胞(HPnMECs)のcell line の作成2008

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第109回山口大学医学会学術講演会
    • Place of Presentation
      宇部
    • Year and Date
      2008-02-09
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Blood-Brain Barrier Pharmacoproteomics (PPx): Targeted absolute proteomics-based pharmacokinetics as a new path for the blood-brain barrier research2008

    • Author(s)
      T. Terasaki, Y. Uchida, J. Kamiie, S. Ohtsuki
    • Organizer
      BLOOD-BRAIN BARRIER CONSORTIUM CLUB Symposium: 'The impact of efflux transports on CNS drug distribution'
    • Place of Presentation
      Gordon Museum, Hodgkin Building, King's College Guy's Campus, London, United Kingdom
    • Year and Date
      2008-11-14
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Targeted proteomics analysis of tight junction proteins expressed at the blood-brain barrier2008

    • Author(s)
      S. Ohtsuki, S. Murata, Y. Katsukura, J. Kamiie, P.O. Couraud, T. Terasaki
    • Organizer
      The 11th international symposium on "Signal transduction in the Blood-Brain Barriers"
    • Place of Presentation
      Amsterdam, Netherlands
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 血液神経関門のregulator は血管周皮細胞である2008

    • Author(s)
      清水文崇, 寺崎哲也, 神田隆
    • Organizer
      第19回日本末梢神経学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-09-05
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] 血液神経関門を構成する内皮細胞におけるトランスポーター発現解析2007

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第48回日本神経学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ラット血液脊髄関門in vitroモデルの確立2007

    • Author(s)
      前田敏彦, 寺崎哲也, 帯刀益夫, 高橋利一, 上田正次, 神田隆
    • Organizer
      第108回山口大学医学会学術講演会
    • Place of Presentation
      宇部
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ain barrier transport protein for the brain drug delivery2007

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      6th Retrometabolism Based Drug Design and Targeting Conference
    • Place of Presentation
      Budapest, Hungary
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 温度感受性SV40 ラージT抗原を用いた新たなヒトin vivo BBB modelの樹立2007

    • Author(s)
      佐野泰照, 寺崎哲也, 神田隆
    • Organizer
      第19回日本神経免疫学会学術集会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Functional expression of transporters for organic anion at the blood-brain barrier2007

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      7th Cerebral Vascular Biology International Conference
    • Place of Presentation
      Ottawa, Canada
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 血液神経関門を構成する内皮細胞におけるtransporter発現解析2007

    • Author(s)
      安部真彰, 寺崎哲也, 神田隆
    • Organizer
      第107回山口大学医学会学術講演会
    • Place of Presentation
      宇部
    • Year and Date
      2007-02-17
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ラット血液神経関門を構成する内皮細胞とpericyte を用いたin vitro BNB model の作成2007

    • Author(s)
      清水文崇, 寺崎哲也, 神田隆
    • Organizer
      第48回日本神経学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Special Lecture: Quantitative proteomics in transporter biology as a new strategy of the drug delivery research2007

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      International Workshop and Symposium on Transport, Metabolism and Disposition
    • Place of Presentation
      Seoul, Korea
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] A new conditionally immortalized human brain microvascular endothelial cell line2007

    • Author(s)
      Sano Y, Terasaki T, Kanda T
    • Organizer
      Neuroscience 2007
    • Place of Presentation
      San Diego, USA
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] ラット血液脊髄関門in vitro モデルの確立2007

    • Author(s)
      前田敏彦, 寺崎哲也, 神田隆
    • Organizer
      第48回日本神経学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Quantitative proteomics as a path to new blood-brain barrier research2007

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      Tenth Symposium Signal Transduction in the Blood-Brain Barriers
    • Place of Presentation
      Potsdam, Germany
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] 血液神経関門(BNB)を構成する血管周皮細胞(pericyte)のcell line の作成2007

    • Author(s)
      清水文崇, 寺崎哲也, 神田隆
    • Organizer
      第108回山口大学医学会学術講演会
    • Place of Presentation
      宇部
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] 温度感受性SV40 ラージT 抗原を用いた新たなヒトin vitro BBB modelの確立2007

    • Author(s)
      佐野泰照, 寺崎哲也, 神田隆
    • Organizer
      第48回日本神学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] BBB構成内皮細胞でのtransporter発現に対するIFN-β1b の効果2007

    • Author(s)
      中山寛人, 寺崎哲也, 神田隆
    • Organizer
      第48回日本神経学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Quantitative and Simultaneous LC-MS/MS Analysis for Membrane Proteins: Its Application for the Blood-Brain Barrier Biology2006

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      Invited lecture at Seminar of Institut Cochin
    • Place of Presentation
      Paris, France
    • Year and Date
      2006-12-22
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] ラット血液神経関門in vitro モデルの確立とtransporter発現解析2006

    • Author(s)
      佐野泰照, 寺崎哲也, 神田隆
    • Organizer
      第47回日本神経学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] 血液神経関門を構成する微小血管内皮細胞の機能解析2006

    • Author(s)
      佐野泰照, 神田隆, 寺崎哲也
    • Organizer
      第6回山陽神経フォーラム
    • Place of Presentation
      山口
    • Year and Date
      2006-10-21
    • Data Source
      KAKENHI-PROJECT-18390259
  • [Presentation] Quantitative proteomics for membrane proteins as a new strategy for the blood-brain barrier biology2006

    • Author(s)
      T. Terasaki, J. Kamiie, S. Ohtsuki
    • Organizer
      Invited lecture at Seminar of Universite d'Atrois
    • Place of Presentation
      Lens, France
    • Year and Date
      2006-12-20
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Brain-to-blood efflux transporters at the blood brain barrier as a CNS detoxifying system2005

    • Author(s)
      T. Terasaki, S. Ohtsuki
    • Organizer
      1th Indo-Japanese Conference on Advances in Pharmaceutical Research and Technology - with special emphasis on Drug Discovery and Drug Delivery
    • Place of Presentation
      Mumbai, India
    • Data Source
      KAKENHI-PROJECT-17081002
  • [Presentation] Drug Transporter Proteomics for Discovery and Profiling.

    • Author(s)
      Terasaki T
    • Organizer
      5th FIP Pharmaceutical Sciences World Congress
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-04-13 – 2014-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Overview: Recent progress in the regulation of blood-brain barrier(BBB)

    • Author(s)
      寺崎哲也
    • Organizer
      第37回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-11 – 2014-09-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Molecular subclassification of glioblastoma based on the absolute quantitative proteomics.

    • Author(s)
      Nakada M, Obuchi W, Ohtsuki S, Tanaka S, Furuta T, Kitabayashi T, Sabit H, Terasaki T, Hayashi Y.
    • Organizer
      Society for Neuro-Oncology 19th Annual Meeting 2014
    • Place of Presentation
      Loews Miami Beach Hotel (Miami, Florida, USA)
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-26670638
  • [Presentation] Quantitative proteomics-based investigation of regulatory mechanism for P-glycoprotein efflux activity at the blood-brain barrier in central nervous system disease: epilepsy and inflammation.

    • Author(s)
      Uchida Y., Hoshi Y., Tachikawa M., Ohtsuki S., Terasaki T.
    • Organizer
      日本薬物動態学会第28年会
    • Place of Presentation
      東京都江戸川区
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Involvement of caveolin-1 tyrosine 14 and src tyrosine 419 phosphorylation levels in intrinsic P-glycoprotein transport function at human blood-brain barrier.

    • Author(s)
      Hoshi Y,Uchida Y, Tachikawa M, Ohtsuki S, Terasaki T
    • Organizer
      5th FIP Pharmaceutical Sciences World Congress
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-04-13 – 2014-04-16
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Phosphorylation of actin filament-associated protein as a regulatory mechanism of intrinsic P-glycoprotein transport activity in human brain capillary endothelial cells: A study of LC-MS/MS based-comprehensive and comparative phospho-proteomics.

    • Author(s)
      Hoshi Y, Uchida Y, Tachikawa M, Terasaki T
    • Organizer
      19th North American ISSX/29th JSSX Meeting,
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2014-10-19 – 2014-10-23
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 絶対定量プロテオミクスによる新規膠芽腫サブタイプ分類の臨床的有用性の検討

    • Author(s)
      中田光俊,田中慎吾,小渕 航,大槻純男,古田拓也,宮下勝吉,寺崎哲也,林 裕
    • Organizer
      第15回日本分子脳神経外科学会
    • Place of Presentation
      山形(大手門パルズ)
    • Year and Date
      2014-09-25 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-26670638
  • [Presentation] Phosphoproteomic approach to clarify regulatory mechanism for intrinsic transport function of one P-glycoprotein molecule at blood-brain barrier: Involvement of tyrosine 14 phosphorylation in caveolin-1.

    • Author(s)
      Hoshi Y., Uchida Y., Tachikawa M., Ohstuki S., Terasaki T.
    • Organizer
      日本薬物動態学会第28年会
    • Place of Presentation
      東京都江戸川区
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Prediction of in vivo blood-brain barrier drug transport from in vitro study combined with transporter protein quantification.

    • Author(s)
      Terasaki T
    • Organizer
      The Transporter Conference-2014
    • Place of Presentation
      Budapest, Hungary
    • Year and Date
      2014-04-03 – 2014-04-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Quantitative Targeted Absolute Proteomics as A Novel Technology for the Drug Transporter Research

    • Author(s)
      Terasaki T
    • Organizer
      20th International Symposium on Microsomes and Drug Oxidations
    • Place of Presentation
      Stuttgart, Germany
    • Year and Date
      2014-05-18 – 2014-05-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Pharmacoproteomics: 定量的標的絶対プロテオミクスに基づく薬剤学の新展開

    • Author(s)
      寺崎哲也
    • Organizer
      薬剤学教科担当教員会議
    • Place of Presentation
      富山市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Transport characteristics of exosomes in human brain capillary endothelial cells.

    • Author(s)
      Kuroda H, Tachikawa M, Uchida Y, Terasaki T
    • Organizer
      19th North American ISSX/29th JSSX Meeting
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2014-10-19 – 2014-10-23
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] ヒト血液脳脊髄液関門におけるトランスポータータンパク質発現量及びラットとの種差の解明

    • Author(s)
      張正宇、内田康雄、立川正憲、寺崎哲也
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 定量的標的絶対プロテオミクスに基づくDDS研究の新展開

    • Author(s)
      寺崎哲也
    • Organizer
      静岡DDSカンファランス
    • Place of Presentation
      静岡市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 標的絶対定量プロテオミクスに基づくがん分子標的化学療法の個別・層別化基盤の構築

    • Author(s)
      内田康雄、立川正憲、小渕航、大槻純男、中田光俊、濱田潤一郎、寺崎哲也
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] 定量的標的絶対プロテオミクスに基づく癌化学療法の新展開

    • Author(s)
      寺崎哲也
    • Organizer
      APSTJ2025WGシンポジウム
    • Place of Presentation
      東京都千代田区
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Blood-Brain Barrier Research: Background, Methodology and Quantitative Targeted Proteomics, Short Course, VI: How we can deliver Drugs across the Barriers by Transporters

    • Author(s)
      Terasaki T
    • Organizer
      The Globalization of Pharmaceutics Education Network (GPEN-2014)
    • Place of Presentation
      Helsinki, Finland
    • Year and Date
      2014-08-27 – 2014-08-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] 膜タンパク質を標的とした定量的標的プロテオミクスに基づく悪性脳腫瘍に対する個別化分子標的療法

    • Author(s)
      小渕航、大槻 純男、中田 光俊、内田 康雄、立川 正憲、濱田 潤一郎、寺崎 哲也
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-24659063
  • [Presentation] Pharmacoproteomics(PPx)に基づく血液脳関門P-gp・Bcrpの輸送機能の再構築

    • Author(s)
      内田康雄、大槻純男、寺崎哲也
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      名古屋市
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Species difference in transporter protein expression levels at the blood-cerebrospinal fluid barrier between human and rat.

    • Author(s)
      Cho S., Uchida Y., Tachikawa M., Terasaki T.
    • Organizer
      日本薬物動態学会第28年会
    • Place of Presentation
      東京都江戸川区
    • Data Source
      KAKENHI-PROJECT-24249011
  • [Presentation] Pharmacoproteomics: Quantitative targeted absolute proteomics (QTAP) and its application to the re-construction of in vivo protein function.

    • Author(s)
      Terasaki T
    • Organizer
      5th FIP Pharmaceutical Sciences World Congress
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-04-13 – 2014-04-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249011
  • []

  • []

  • []

  • 1.  HOSOYA Ken-ichi (70301033)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 9 results
  • 2.  OHTSUKI Sumio (60323036)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 57 results
  • 3.  SUGIYAMA Yuichi (80090471)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 4.  KATO Yukio (30251440)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  UCHIDA Yasuo (70583590)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 85 results
  • 6.  TSUJI Akira (10019664)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TACHIKAWA Masanori (00401810)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 67 results
  • 8.  YAMAZAKI Masayo (40240741)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 9.  SUZUKI Hiroshi (80206523)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  NAKADA Mitsutoshi (20334774)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 11.  TAKIKAWA Hajime (70197226)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  KAMIIE Junichi (10400269)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 13.  KANDA Takashi (40204797)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 32 results
  • 14.  TAMAI Ikumi (20155237)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  橋田 満 (20135594)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  TAKENAKA Shoji (70006344)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  TOMI Masatoshi (30334717)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 18.  OBINATA Masuo (10099971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  TAKANAGA Hitomi (20284523)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  ASASHIMA Tomoko (00400268)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  井上 正康 (80040278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  安原 眞人 (00127151)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  前田 浩 (90004613)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  MORI Shinobu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  WATANABE Michitoshi (40303127)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  HAMADA Junichiro (40253752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KOBAYASHI Tomoo (70085645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  INABA Makoto (60085636)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  YAMANAKA Masami (20082109)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  NAKAMURA Toshikazu (00049397)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  AOKI Junken (20250219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  CHIBA Kan (40159033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  HARASHIMA Hideyoshi (00183567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  SHINOHARA Yasuo (60226157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  KIKUCHI Akihiko (40266820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  YANAI Nobuaki (80200525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  MATSUI Yasuhisa (40241575)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  ENDO Hiyoshi (20101115)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  ABE Takaaki (80292209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  SAKURADA Shinobu (30075816)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  MIZOGUCHI Hirokazu (30360069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  SHUKURU Hemurasabit (10432113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  佐藤 均 (40187224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  中尾 一和 (00172263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  片岡 一則 (00130245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  高橋 威夫 (70004653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  伊藤 慎吾 (20466535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  石川 智久 (60193281)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  堀 里子 (70313145)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  吉田 将人 (80511906)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 51.  臼井 拓也 (50835296)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 52.  NAMIKI Mitsuo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  SASAHARO Kunihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  FUKUSHIMA Kiyomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  UEDA Masatsugu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  FUROTA Takuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 57.  伊藤 慎悟
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 58.  鈴木 貴
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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