• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

SUGINO Akio  杉野 明雄

ORCIDConnect your ORCID iD *help
Researcher Number 90231737
Affiliation (based on the past Project Information) *help 2006: 大阪大学, 大学院生命機能研究科, 教授
2006: 阪大, 教授
2003 – 2005: 大阪大学, 大学院・生命機能研究科, 教授
2003 – 2004: 大阪大学, 生命機能研究科, 教授
2002: 教授 … More
1992 – 2001: 大阪大学, 微生物病研究所, 教授
1993: 大阪大学, 微生物研究所, 教授
1992 – 1993: 大阪大学, 微研, 教授 Less
Review Section/Research Field
Principal Investigator
Molecular biology / Biological Sciences / Molecular biology
Except Principal Investigator
Molecular biology / Cell biology
Keywords
Principal Investigator
DNAポリメラーゼ / 出芽酵母 / Cdc7 / Dbf4 protein kinase / DNAポリメラーゼε / 染色体DNA複製 / クローニング / DNAヘリカーゼ / 細胞周期 / Dbf4複合体 … More / Dbf4 protein kinase complex / RF-C複合体 / Eukaryotic chromosomal DNA replication / Cdc7-Dbf4複合体 / In vitro DNA複製 / Saccharomyces cerevisiae / 遺伝子発現 / 分裂酵母 / 蛋白リン酸化酵素 / Xenopus egg in vitro replication system / Protein kinase / Rad53p / S-phase checkpoint / Mcm10 protein / Mcm2-7 protein complex / Chromosomal DNA replication / Sー期チェックポイント / Xenopus egg / in vitro 複製系 / Dbf4p複合体 / Cdc7p / MCM10蛋白 / Xenopus egg in Vitro Replication system / Rad53蛋白 / S-期チェックポイント / Mcm10蛋白 / Mcm2-7蛋白群 / 染色体DNA複製開始機構 / Checkpoint control / Mcm2-7 complex / DNA helicase / Lagging strand synthesis apparatus / Leading strand synthesis apparatus / 細胞周期チェックポイント / PCNA / Lagging鎖合成装置 / Leading鎖合成装置 / 真核生物染色体DNA複製 / Mcm蛋白複合体 / ヘリカーゼ / Bloom症候群原因遺伝子産物 / チェックポイント制御 / Dbf4プロテインキナーゼ / Mcm2-7蛋白複合体 / Lagging鎖複製装置 / Leading鎖複製装置 / 真核生物染色体複製機構 / Sld / Dpb11 / DNA polymeraseII (epsilon) / Mcm10 / Mcm2-7 proteins / S.pombe / S.cerevisiae / Dbf-Cdc7複合体 / ORC / 複製開始因子 / Mcm蛋白群 / 複製ライセンス因子 / DNA polymerase complex / RF-C complex / Budding yeast / Insect cells / Baculovirus expression vector / Expression vector / DNA Replication protein complex / RFC複合体 / YACベクター / バキュロウイルスベクター / DNAポリメラーゼ複合体 / Cdc7-Dbf4 protein kinase複合体 / 昆虫細胞 / バキューロウイルスベクター / 多量発現ベクター / DNA複製複合体 / phosphatase / Cdc 7-Dbf4 complex / three DNA polymerase model / DNA polymerase subunits / DNA polymerase III (delta) / DNA polymerase II (epsilon) / 蛋白精製 / DNAポリメラーゼ補助因子 / 複製開始部位 / ORC蛋白 / 細胞周期チェックポイント制御 / Phosphatase / 細胞周期チェックポイントコントロール / DNAポリメラーゼサブユニット / DNAボリメラーゼ / 真核細胞染色体DNA複製 / ミューテーター / マウスES細胞 / 癌 / 遺伝学 / pre RC (複製開始名複合体) / 複製開始 / セントロメア / アフリカツメガエル卵粗抽出液 / Polε複合体 / GINS / Db4f protein kinase / Cdc / Mcm蛋白 / pre RC(複製開始前複合体) / ほ乳動物細胞 / チェックポイント / 哺乳動物細胞 / アフリカツメガエル / 染色体複製 / YEL055C / DNAポリメラーゼβ / DNA修復 / double strand break repair / in vitro DNA repair / Yeast Saccharomyces cerevisiae / DNA ポリメラーゼε / DNA ポリメラーゼβ / DNA repair / 塩基配列 / DNA polymerase II / Drosophila melanogaster / Northern hybridization / CDC7 homolog / DBF4 / CDC7 / 出芽酵母S.cerevisiae / protein kinase / 染色体DNA複製開始 / PCR / 発生と分化 / ショウジョウバエ / ガン化の機構 / 突然変異株 / CDC7遺伝子 / ヒト染色体DNA複製開始 / DNAポリメラーゼα-プライマーゼ / 一本鎖DNA結合蛋白 / CDC / 真核細胞染色体複製 / ORC複合体 / multicopy suppressor / チェックポイントコントロール / CDC7-DBF4複合体 / 染色体複製開始 … More
Except Principal Investigator
DNA複製 / ゲノム情報 / ノックアウトマウス / DNA修復 / ライセンス因子 / 細胞分裂 / 染色体分配 / 複製起点 / 複製蛋白 / がん遺伝子 / サイクリン / 細胞周期 / International collabolation / Proteomics / Genomics / Asia-Pacific Molecular Biology Network / Asia and Pacific Rim region / Frontier Life Sciences / プロテオーム / 国際共同研究 / プロテオミックス / ゲノミックス / 分子生物学ネットワーク(A-IMBN) / アジア環太平洋地域 / 先端生命科学 / XAB / importin / ターゲティング / DNA polymerase / コケイン症候群 / POU / SOX / 細胞分化 / インポーティン / DNA損傷 / レチノイン酸 / 転写調節因子 / アポトーシス / 細胞内物質輸送 / シグナル分子 / 転写調節 / 遺伝病 / がん / 遺伝的不安定性 / 自然突然変異 / 遺伝子 / DNAポリメラーゼ / DNA組換え / DNA / 突然変異 / 酸素ラジカル / 繰り返し配列 / フレームシフト / 酵素ラジカル / ミスマッチ修復 / 複製エラー / 複製開始 / DnaA / SeqA / 複製開始の調節 / 複製装置 / チェックポイント / 複製開始蛋白 / 転写 / 組換え / 修復 / 複製 / 遺伝情報維持 / DNAトランスアクション / TGFbeta / RB蛋白質 / cdc2キナーゼ / DNAポリメラーゼalpha / がん抑制遺伝子 / RecA / RAD51 / ホットスポット / 遺伝子組換え / 減数分裂 / 組換えホットスポット / 非相同組換え / 相同組換え / 核骨格 / ホリデー構造 / 組換え蛋白 / 組換え遺伝子 / 複製酵素 / 複製遺伝子 / ARS配列 / 複製開始点 / ゲノム複製 / ^<cdc2>キナーゼ / RV蛋白質 / TGFβ / ユビキチン / 癌抑制遺伝子 / 癌遺伝子 Less
  • Research Projects

    (25 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (68 People)
  •  DNAポリメラーゼεミューテーター変異マウスの構築とその発がん機構の解析Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  DNAポリメラーゼεミューテーター変異マウスの構築とその発がん機構の解析Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  真核生物染色体DNA複製フォークの分子ダイナミズムPrincipal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  個体生命を支える素機構の統合

    • Principal Investigator
      近藤 寿人 (近藤 壽人)
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for COE Research
    • Research Institution
      Osaka University
  •  Development of frontier life science research for prevention and therapy of endemic diseases in Asia and the Pacific Rim Region

    • Principal Investigator
      KOIKE Katsuro
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Special Purposes
    • Research Institution
      Japanese Foundation for Cancer Research
  •  DNA Replication Apparatus and S-Phase Checkpoint ControlPrincipal Investigator

    • Principal Investigator
      SUGINO Akio
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  細胞複製装置:染色体の複製・分配機構

    • Principal Investigator
      平賀 壮太 (平賀 壯太 / 平賀 莊太)
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  突然変異の分子病態

    • Principal Investigator
      真木 寿治
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nara Institute of Science and Technology
  •  Molecular Mechanism of Initiation of DNA ReplicationPrincipal Investigator

    • Principal Investigator
      SUGINO Akio
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  Molecular Mechanism of Chromosomal DNA Replication ApparatusPrincipal Investigator

    • Principal Investigator
      SUGINO Akio
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Research Institute for Microbial Diseases, Osaka University
  •  真核生物DNA修復反応におけるDNAポリメラーゼβ及びεの役割Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  細胞複製装置:染色体の複製・分配機構

    • Principal Investigator
      平賀 壯太
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kumamoto University
  •  EXPRESSION OF EUKARYOTIC DNA REPLICATION PROTEIN COMPLEXS AND THEIR SIMPLE PURIFICATION METHODPrincipal Investigator

    • Principal Investigator
      SUGINO Akio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  真核生物DNA修復反応におけるDNAポリメラーゼβ及びεの役割Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  DNAトランスアクションと遺伝情報の安定性

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Osaka University
  •  組換え機構の分子的基礎

    • Principal Investigator
      堀田 康雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  細胞周期の制御機構における癌遺伝子、癌抑制遺伝子および関連遺伝子の研究

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ヒト染色体DNA複製開始を制御している遺伝子の単離と解析Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  ショウジョウバエDNAポリメラーゼεの細胞内での役割Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Molecular biological and genetical study on the mechanism of chromosomal DNA replicaiton in eukaryotes -Yeast as a model-Principal Investigator

    • Principal Investigator
      SUGINO Akio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      Osaka University
  •  真核細胞染色体複製開始の細胞周期による制御機構の研究Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  細胞周期の制御機構における癌遺伝子・癌抑制遺伝子および関連遺伝子の研究

    • Principal Investigator
      花岡 文雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The Institute of Physical and Chemical Research
  •  ヒト染色体DNA複製開始を制御している遺伝子の単離と解析Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  ゲノム複製開始の制御

    • Principal Investigator
      吉川 寛
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nara Institute of Science and Technology
      Osaka University
  •  ショウジョウバエDNAポリメラーゼεの細胞内での役割Principal Investigator

    • Principal Investigator
      杉野 明雄
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University

All 2006 2004

All Journal Article

  • [Journal Article] Historical view of DNA replication studies, with special reference to Japan.2006

    • Author(s)
      Sugino, A.
    • Journal Title

      IUBMB Life 58

      Pages: 323-327

    • Data Source
      KAKENHI-PROJECT-15107003
  • [Journal Article] Distinct roles of DNA polymerases, delta and epsilon at the replication fork in Xenopus egg extracts.2004

    • Author(s)
      Fukui, T., Waga, S., Sugino, A., et al.
    • Journal Title

      Genes Cells 9

      Pages: 179-191

    • Data Source
      KAKENHI-PROJECT-12CE2007
  • 1.  川崎 泰生 (30243257)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  MAKI Hisaji (20199649)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIDA Shonen (70090420)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  花岡 文雄 (50012670)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  荒木 弘之 (20151160)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  松影 昭夫 (90019571)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  平賀 壯太 (40027321)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  ITO Yoshiaki (80004612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  MAKI Satoko (60212205)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  TSURIMOTO Toshiki (30163885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  野瀬 清 (70012747)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  田矢 洋一 (60133641)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  金田 澄子 (60152815)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  井出 利憲 (60012746)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  吉川 寛 (70019876)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  堀内 嵩 (60108644)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  清水 喜久雄 (20162696)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  滝澤 温彦 (60154944)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  岡部 勝 (30089875)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 20.  奥野 友紀子 (00372524)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 21.  JOHNSTON Lel
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  LEEM Sun-hee (40263313)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  MASAI Hisao (40229349)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  ITOH Tateo (40051817)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SUGIMOTO Katsunori (90192616)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  OHMORI Haruo (10127061)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  HIRAGA Shin-ichiro (90322172)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  KOIKE Katsuro (30085625)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  ASASHIMA Makoto (00090564)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  MIYAJIMA Atsushi (50135232)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  ARAI Ken-ichi (00012782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  山口 和男 (00019879)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  堀内 賢介 (70219210)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  今本 文男 (00029761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  小笠原 直毅 (10110553)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  堀田 康雄 (30190218)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  城石 俊彦 (90171058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  小林 一三 (30126057)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  大坪 栄一 (10158800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 40.  小川 英行 (70028207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  柴田 武彦 (70087550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  関口 睦夫 (00037342)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 43.  升方 久夫 (00199689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 44.  柳田 充弘 (80025428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 45.  岡崎 恒子 (10022584)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 46.  続 輝久 (40155429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 47.  葛西 宏 (40152615)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 48.  能美 健彦 (30150890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 49.  中村 健司 (90253533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 50.  林 健志 (00019671)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 51.  近藤 寿人 (70127083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 52.  濱田 博司 (00208589)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  田中 亀代次 (80144450)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  辻本 賀英 (70132735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  米田 悦啓 (80191667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  関 丘 (40271118)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  和賀 祥 (60222402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  榎本 武美 (80107383)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  ISHIMI Yukio
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  MORRISON Ala
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  DIFFLEY John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  CAMPBELL Jud
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  TYE BikーKwoo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  JOHN.F.X. Diffey
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  LELAND H. Johnston
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  BIK-KWOON Tye
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  JUDITH L. Campbell
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  TYE Bik Kwoo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi