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HAMADA Hirohumi  濱田 洋文

ORCIDConnect your ORCID iD *help
… Alternative Names

濱田 博文  ハマダ ヒロフミ

浜田 洋文  ハマダ ヒロフミ

濱田 洋文  ハマダ ヒロフミ

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Researcher Number 00189614
Other IDs
Affiliation (based on the past Project Information) *help 2011 – 2013: 東京薬科大学, 生命科学部, 教授
1999 – 2010: Sapporo Medical College, Medicine, Professor, 医学部, 教授
2007: 札幌医科大学, 医学部, 准教授
2005: 札幌医科大学, 医学部分子医学部門, 教授
2003: Sapporo Medical University, Dept. of Molecular Medicine, Professor, 分子医学研究部門, 教授 … More
2003: 札幌医科大学, 医学部・分子医学研究部門, 教授
2001: 札幌以下大学, 医学部, 教授
2001: 札幌医科大学, 医学部・分子医学研究部門, 教授
1998 – 2000: 癌研究会, 癌科学療法センター, 分子生物治療研究部長
1999: (財)癌研究会, 分子生物治療研究部, 部長
1999: 札幌医科大学, 分子医学, 教授
1998: (財)癌研究会, 分子生物治療研究部, 部長(研究職)
1998: Japanese Cancer Institute, Cancer Chemotherapy Center, Chief., 部長
1998: Cancer Institute, virology, Director, 化学療法センター・分子生物治療研究部, 部長
1998: 癌研究会, 癌化学療法センター分子生物治療研究部, 部長
1998: 癌研究会化学療法センター, 分子生物治療研究部, 部長
1998: 癌研究所分子生物治療部, 部長(研究職)
1997 – 1998: (財)癌研究会癌化学療法センター, 分子生物治療研究部, 部長
1997: 癌研究会, 化学療法センター分子生物治療研究部, 部長
1997: 財団法人癌研究会, 癌化学療法センター・分子生物治療研究部, 部長
1996: 癌研究会, 化学療法センター, 部長
1996: 癌研究会, 化学療法センター・分子生物治療研究部, 部長
1996: JAPANESE FOUNDATION FOR CANCER RESEARCH,CANCER CHEMOTHERAPY CENTER,DEPARTMENT OF, 分子生物治療研究部, 部長
1993 – 1996: 財団法人癌研究會, 癌化学療法センター・分子生物治療研究部, 部長
1995: 財団法人癌研究曾, 癌化学療法センター・分子生物治療研究部, 部長
1994 – 1995: (財)癌研究会癌化学療法センター, 分子生物治療研究部, 部長
1994: がん研究所, 部長
1994: 癌化学療法センター, 分子生物治療、研究部, 部長
1993: (財)癌研究会癌研究所, 癌化学療法センター・分子生物治療研究部, 部長
1993: Cancer Chemotherapy Center, 癌化学療法センター, 部長
1993: 財団法人癌研究會, 癌化学療法センター・分子生物治療研究部・部長10DA01:99999999
1989: 癌研究会, 癌化学療法センター・基礎研究部, 研究員
1988 – 1989: 癌研究会癌化学療法センター, 基礎研究部, 研究員
1987: (財)癌研究会, 癌化学療法センター・基礎研究部, 研究員
1986: (財)癌研究会癌化学療法センター, 基礎研究部, 嘱託研究員 Less
Review Section/Research Field
Principal Investigator
Cerebral neurosurgery / Biological Sciences / Dermatology / Immunology / Hematology
Except Principal Investigator
General surgery / Cerebral neurosurgery / Gastroenterology / Cerebral neurosurgery / Circulatory organs internal medicine … More / Digestive surgery / Hematology / Circulatory organs internal medicine / Gastroenterology / Metabolomics / Dermatology / Clinical oncology / Laboratory medicine / Digestive surgery / 病態科学系歯学(含放射線系歯学) / General anatomy (including Histology/Embryology) / 内分泌・代謝学 Less
Keywords
Principal Investigator
遺伝子治療 / アデノウイルスベクター / ファイバー / 悪性黒色腫 / receptor / がん / ペプチドリガンド / 受容体 / 悪性脳腫瘍 / モノクローナル抗体 … More / 悪性神経膠腫 / レトロウイルス・ベクター / adenoviral fiber / peptide ligand / malignant glioma / Gene therapy / モノクローン抗体 / ファイバー変異型 / 前立腺癌 / B細胞系の腫瘍 / 膵癌 / 樹状細胞 / CD82 / 腫瘍ワクチン / アデノウイルス / アポトーシス / T細胞活性化 / p53 / EIA / 脳腫瘍 / malignant melanoma / integrin / adenoviral vector / 養子免疫療法 / サイトカイン / cancer treatment / gene therapy / RGDモチーフ / 間葉系幹細胞 / 癌治療 / 浸潤 / 変異型アデノウイルスベクター / 標的化 / fiber / cancer / Adenoviral vector / 悪性黒色癌 / インテグリン / tumor / malignant melanama / Adeno viral vector / 悪性黒色種 / Brain Tumor / Apoptosis / Fiber mutant / Cancer Gene Therapy / Adenoviral Vector / Bax / アデノウイルス ファイバー / がん遺伝子治療 / アテノイルスベクター / 遺伝子冶療 / 標的化遺伝子導入 / 標的化抗体 / アデノウィルスベクター / 安全性評価 / 膀胱癌 / 口腔癌 / NG2 / 分子標的 / がん治療 / アデノウルスベクター / 発現クローニング / 抗原提示 / 腫瘍ワクチン療法 / ウイルスベクター / IL-4 / GM-CSF / サイトカイン遺伝子 / 癌免疫 / 抗原提示細胞 / レトロウイルス / 自殺遺伝子導入療法 / 免疫遺伝子治療 / グリオーマ / 免疫制御 / 腫瘍抑制遺伝子 / gastrin releasing peptide / melanocyte stimutating hormone / melanoma / fiber mutant / cancer gene therapy / 殺細胞Tリンパ球 / TIA1 / アデノウイルス・ベクター / 癌転移 / タンパク精製 / ボイデンチェンバー / 細胞運動促進因子 … More
Except Principal Investigator
遺伝子治療 / gene therapy / アデノウイルス / モノクローナル抗体 / transplantation / stroke / infarction / human / gene / adult / VEGF / 遺伝子導入 / 腫瘍ワクチン / サイトカイン / 耐性遺伝子 / 耐性タンパク / アドリアマイシン / ビンクリスチン / 抗癌剤耐性 / 抗癌剤 / 血管新生 / adenovirus / 癌 / レトロウイルス・ベクター / 免疫遺伝子治療 / カルシウム拮抗薬 / CEA / VLA4 / Angiopoietin-1 / plasmid DNA / electroporation / neural stem cell / bone marrow / Ex vivo / Ephrin B2 / bFGF / ラビット / TRAF / ウサギ / gene transfer / inflammation / PAF-AH / TFPI / 炎症 / 糖尿病 / CTLA4Ig / adenoviral vector / p53 / CD82 / IL-12 / thrombomodulin / 悪性神経膠腫 / Gene Therapy / 細胞接着 / AML / 胆道癌 / 発生・分化 / 脳・神経 / 神経科学 / 再生医学 / 移植・再生医療 / 抗体 / ウイルスベクター / アデノウィルス / アポトーシス / 脳腫瘍 / 樹状細胞 / 悪性脳腫瘍 / gastric cancer / antibody / 胃癌 / neuroprotection / integrin / bile duct cancer / gallbladder cancer / biliary cancer / コクサッキー・アデノウイルス受容体 / インテグリン / 胆管癌 / 胆嚢癌 / Humanized chimeric antibodies / キメラ抗体 / 急性白血病 / ヒト化キメラ抗VLA4抗体 / 急性骨髄性白血病 / Viral Vector / Ischemic Heart Disease / Myocardial Infarction / 間葉系幹細胞 / 虚血性心疾患 / 心筋梗塞 / tumor / spinal cord injury / microarray analysis / PDX-1 gene / pancreatic islet regeneration / insulin secreting cell / pancreatic ductal epithelium / 膵再生 / PDX-1 / angiopoietin / 膵ラ島 / マイクロアレイ / PDX1 / ラ島 / 膵管上皮細胞 / マイクロアレイ解析 / PDX-1遺伝子 / 膵ラ島再生 / インシュリン産生細胞 / 膵管上皮細 / advanced gastrointestinal cancer / novel mutant p53 / アデノウイスルベクター / 進行消火器癌 / アデノウイルスベクター / 進行消化器癌 / 新規変異p53遺伝子 / Gene therapy / Rabbit / Angiogenic therapy / 虚血肢 / ラテンウイエルス / Ephrine B2 / Therapeutic angiogenesis / ポリエチレンイミン / CD40リガンド / Eph B4 / Ex vivo法 / ウサギ下肢虚血モデル / 血管新生療法 / smooth muscle cell / intimal hyperplasia / rabbit / reinjury / stent / Protein kinase C / Protein kinase B / 再障害モデル / 血管内ステント / p70^<S6k> / Pootion kinase C / Phosphatidylinositol-3-kinase / 平滑筋細胞 / 内膜肥厚 / 再障害 / ステント / C-type natriuretic peptide / extracelluar matrix protein / injured arteries / thrombosis / TGF-β / 人工血管 / 抗血栓分子 / 不全心筋 / 傷害血管 / 再狭窄 / 血栓症 / CNP / 細胞外基質 / 障害血管 / 血栓 / TKY rat / W / BB / diabetes mellitus / 膵島移植 / BBラット / BB rat / resistance / mutant adenoviral vector / proteasome / apoptosis / brain tumor / アデノウイルスペクター / 悪性髄膜腫 / 抗アポトーシス因子 / K20 fiber mutant adenovirus / F / アボトーシス / 耐性 / 変異アデノウィルスベクター / ブロテアソーム / アデノウィルスベクター / CANCER VACCINATION / CELL ADHESION / MELANOMA / メラノーマ / angiogenesis / cancer / gene gun / 抗腫瘍療法 / 遺伝子統 / P53 / 細胞死 / 腫瘍免疫 / BAI-1 / 抗腫瘍免疫 / 腫瘍血管新生 / 癌の遺伝子治療 / 遺伝子銃 / plasminogen activators / endothelial cell / hybrid-type vascular prosthesis / small caliber vascular prosthesis / PDGF / 小口径人工血管 / 血管内皮細胞 / thrombomonodulin / tissue plasminegen activator / Plasminogen activators / tissue plasminogen activator / ハイブリッド型人工血管 / 内皮細胞 / RETROVIRUS VECTOR / CYTOKINE / TUMOR VACCINE / MALIGNANT GLIOMA / レトロウィルス・ベクター / Drug Design / Cell Adhesion / Cell Cycle / Signal Transduction / Information Exchange / Cancer / International Scientific Research / 細胞増殖 / 癌化学療法 / 癌遺伝子治療 / ドラッグデザイン / 情報交換 / 化学発癌 / 癌治療 / ウイルス発癌 / 薬品設計 / 細胞周期 / シグナル伝達 / 細胞社会学 / 海外派遣 / 国際学術 / Transcriptional regulation / Growth control / Cancer cells / Tumor suppressor gene / Tumor promoter / Tumor virus / Oncogene / Information exchange / 研究集会 / 研究室訪問 / 北米 / 研究交流 / がん研究 / 転写調節 / 増殖制御 / がん細胞 / がん抑制遺伝子 / 発がんプロモーター / ウイルス発がん / がん遺伝子 / 研究情報交換 / カルシウム培抗薬 / ADC / DT3C / イミュノトキシン / 標的治療 / 遺伝子化学療法 / UPRT / 5-fluorouracil / サイクロフォスファマイド / 腫瘍融解ウイルス / 膀胱がん / 大腸がん / 体外診断 / 膀胱癌 / 大腸癌 / 検査・診断 / バイオマーカー / 癌抗原 / 免疫血清学 / skinfold chamber / 変異アデノウイルス / drug delivery system / RGDモチーフ / 増殖型アデノウイルス / 血管内皮前駆細胞 / ミサイル療法 / マネジメント・システム / 品質管理 / cGMP / 組織因子 / 組織特異性 / RB遺伝子 / P53遺伝子 / in vivo / T細胞 / マウス / DNA組換 / oval cell / cell line / 細胞培養 / D-galactosamine / 細胞移植 / 肝細胞 Less
  • Research Projects

    (49 results)
  • Research Products

    (201 results)
  • Co-Researchers

    (150 People)
  •  Generation of immunotoxins with super-targeting mAb in the acute myelocytic leukemia

    • Principal Investigator
      YAMAGUCHI MIKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Clinical oncology
    • Research Institution
      Sapporo Medical University
  •  Evaluation of efficacy and safety of gene-chemotherapy for biliary cancers using oncolytic adenovirus armed with UPRT

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  Therapeutic benefits of the genetically-engineering mesenchymal stem cells for sub-acute cerebral ischemia

    • Principal Investigator
      HONMOU Osamu
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
  •  Research and development of low-invasive and high-sensitive detection system for novel tumor markers by super-targeting monoclonal antibody

    • Principal Investigator
      KATO Kazunori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Juntendo University
      Sapporo Medical University
  •  Selective targeted drug and gene delivery for cancer treatmentPrincipal Investigator

    • Principal Investigator
      HAMADA Hirohumi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  Targeted therapy of gastrointestinal cancer using human anti-CEA antibody

    • Principal Investigator
      TANAKA Toshihiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Fukuoka University
      Sapporo Medical University
  •  Analyses of VLA4 molecule as a prognostic factor for acute leukemia and development of novel therapy for acute leukemia targeting VLA4 molecule

    • Principal Investigator
      NIITSU Yoshiro
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Experimental Efficacy of Fiber-modified Cancer-selectively Replicating Adenovirus for Gene Therapy of Biliary Cancers

    • Principal Investigator
      ABEI Masato
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      University of Tsukuba
  •  A genetically-engineering bone marrow stem cell therapy for stroke

    • Principal Investigator
      HONMOU Osamu
    • Project Period (FY)
      2004 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
  •  Angiopoietin-1 gene therapy for acute myocardial infarction

    • Principal Investigator
      ITO Yoshinori
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Sapporo Medical University
  •  血管内皮前駆細胞をDDSとした癌転移に対するミサイル療法

    • Principal Investigator
      砂村 眞琴
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Induction of insulin secreting cell and its application for transplantation

    • Principal Investigator
      SUNAMURA Makoto
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Targeted gene therapy for brain tumorPrincipal Investigator

    • Principal Investigator
      HAMADA Hirofumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
  •  Functional recovery of the cerebral tissue following transplantation of the genetically-engineering bone marrow stem cells.

    • Principal Investigator
      HONMOU Osamu
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
  •  Development of gene transfer by in vivo electroporation to the vascular wall

    • Principal Investigator
      MIYATA Tetsuro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  組織特異性を有する遺伝子導入ベクター(改変型アデノウイルス)の開発

    • Principal Investigator
      UENO Hikaru
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  臨床応用可能なウイルスベクター製造のための企画調査

    • Principal Investigator
      市川 直哉
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Novel angiogenic gene therapy for the treatment of ischemic limb

    • Principal Investigator
      MIYATA Tetsuro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Development of gene therapy for advanced gastrointestinal cancer utilizing novel mutant p53 gene with effective nuclear translocation

    • Principal Investigator
      TAKAHASHI Minoru
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  腫瘍の特異的標的化を目指した遺伝子治療法の開発Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Sapporo Medical University
  •  多彩な遺伝子異常に対応可能な風邪ウイルスを用いた癌の治療

    • Principal Investigator
      SUNAMURA Makoto
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Gene transfer-mediated molecular analysis of pathophysiology in injured arteries

    • Principal Investigator
      UENO Hikaru
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Occupational and Environmental Health
  •  Signal transduction regulating intimal cell replication in arterial lesion

    • Principal Investigator
      KOYAMA Hiroyuki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  Targeted gene therapy for brain tumorPrincipal Investigator

    • Principal Investigator
      HAMADA Hirofumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
  •  Targeted gene therapy for malignant melanomaPrincipal Investigator

    • Principal Investigator
      HAMADA Hirofumi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Sapporo Medical University
  •  腫瘍の特異的標的化を目指した遺伝子治療法の開発Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Sapporo Medical University
      Japanese Foundation For Cancer Research
  •  脳腫瘍の遺伝子治療の研究

    • Principal Investigator
      篠浦 伸禎
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      The University of Tokyo
  •  Experimental Studies for the Treatment of Malignant Brain Tumors. - Gene Therapy using viral vectors -

    • Principal Investigator
      TAKADA Yoshiaki, 平川 公義
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Targeted Gene Therapy for Brain TumorPrincipal Investigator

    • Principal Investigator
      HAMADA Hirofumi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Sapporo Medical University
      Japanese Foundation For Cancer Research
  •  Prevention of diabetes by CTLA41g-producing islet transplantation

    • Principal Investigator
      KATAYAMA Shigehiro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Saitama Medical University Department of Medicine
  •  Gene therapy for cancer using the gone gun system

    • Principal Investigator
      SUNAMURA Makoto
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Basic Analysis of Immuno-gene Therapy for Melanoma Using Functional Characteristic of CD82

    • Principal Investigator
      SHIBAGAKI Naotaka
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      YAMANASHI MEDICAL UNIVERSITY
  •  T細胞関連樹状細胞のサイトカイン依存性成熟分化経路をin vivoの系で確認する.

    • Principal Investigator
      角田 力弥
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Fukushima Medical University
  •  樹状細胞のT細胞活性化能を応用した口腔癌に対する免疫遺伝子治療法の開発

    • Principal Investigator
      山口 聰
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Development of hybrid-type vascular prosthesis with application of gene transfer technique

    • Principal Investigator
      MIYATA Tetsuro
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  抗原提示樹状細胞の機能修飾による免疫誘導療法Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  IMMUNE THERAPY FOR MALIGNANT GLIOMA USING GENETICALLY-MODIFIED TUMOR CELLS AND T-LYMPHOCYTES

    • Principal Investigator
      HIRAKAWA Kimiyoshi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      TOKYO MEDICAL AND DENTAL UNIVERSITY
  •  肝臓幹細胞培養系を用いた遺伝子治療の基礎的研究

    • Principal Investigator
      林 道夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Japanese Foundation For Cancer Research
  •  サイトカイン発現腫瘍ワクチンを用いた悪性神経膠腫に対する免疫遺伝子治療の基礎研究

    • Principal Investigator
      平川 公義
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  サイトカインを発現するレトロウイルス・ベクターを用いた癌の遺伝子治療の基礎研究Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  アポトーシスを誘導するTIA1の機能の解析Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Japanese Foundation For Cancer Research
  •  レトロウイルス・ベクターを用いた悪性グリオーマに対する遺伝子導入の基礎的研究

    • Principal Investigator
      HIRAKAWA Kimiyoshi
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Tokyo Medical and Dental University
  •  Information Exchange on Cancer Research with North American Countries.

    • Principal Investigator
      YAMAGUCHI Nobuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  抗がん剤耐性の分子機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  癌細胞運動促進因子の精製と機能の解析Principal Investigator

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research

All 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Drug Delivery System2007

    • Author(s)
      加藤和則、濱田洋文
    • Publisher
      標的細胞への選択的遺伝子導入法の開発
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Book] Recent Development in Gene Therapy2007

    • Author(s)
      Tanaka T, Hamada H, Kuroki Ma, et al.
    • Publisher
      RANSWORLD RESERCH NETWORK
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591421
  • [Book] Stem Cell Repair and Regeneration2005

    • Author(s)
      Hamada H
    • Publisher
      Imperial College Press
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Book] Recent Development in Gene Therapy

    • Author(s)
      Tanaka T, Hamada H, Kuroki Ma, et al.
    • Publisher
      RANSWORLD RESERCH NETWORK(In press)
    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Cyclophosphamide enhances antitumor efficacy of oncolytic adenovirus expressing uracil phosphoribosyltransferase (UPRT) in immunocompetent Syrian hamsters2013

    • Author(s)
      Hasegawa N, Abei M, Yokoyama KK, Fukuda K, Seo E, Kawashima R, Nakano Y, Yamada T, Nakade K, Hamada H, Obata Y, Hyodo I
    • Journal Title

      Int. J.Cancer

      Volume: PMID: 23444104(印刷中) Issue: 6 Pages: 1479-1488

    • DOI

      10.1002/ijc.28132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590755, KAKENHI-PROJECT-23501277
  • [Journal Article] IKAROS isoform 6 enhances BCR-ABL1-mediated proliferation of human CD34+ hematopoietic cells on stromal cells2012

    • Author(s)
      Suzuki K, et al
    • Journal Title

      Int J Oncol

      Volume: 40 Pages: 53-62

    • DOI

      10.3892/ijo.2011.1192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591200, KAKENHI-PROJECT-22390206, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23501309
  • [Journal Article] EpCAM- and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber-modified adenovirus2011

    • Author(s)
      Kawashima R, Abei M, Fukuda K, Nakamura K, Murata T, Wakayama M, Seo E, Hasegawa N, Mizuguchi H, Obata Y, Hyodo I, Hamada H, Yokoyama KK.
    • Journal Title

      INTERNATIONAL JOURNAL OF CANCER

      Volume: Sep;129(5) Issue: 5 Pages: 1244-1253

    • DOI

      10.1002/ijc.25758

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Journal Article] EpCAM- and EGFR- targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus2011

    • Author(s)
      Kawashima R, Abei M, Fukuda K, Nakamura K, Murata T, Wakayama M, Seo E, Hasegawa N, Mizuguchi H, Obata Y, Hyodo I, Hamada H, Yokoyama KK
    • Journal Title

      Int. J. Cancer

      Volume: 129巻 Pages: 1244-1253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Journal Article] Bone marrow stromal cell line promotes the proliferation of mast cell progenitors derived from cord blood CD34+ cells under serum-free conditions with a combination of both cell-cell interaction and soluble factors.2011

    • Author(s)
      Fujihara M, Azuma H, Ikeda H, Yamaguchi M, Hamada H.
    • Journal Title

      Artif Cells Blood Substit Immobil Biotechnol

      Volume: Apr;39(2) Issue: 2 Pages: 51-58

    • DOI

      10.3109/10731199.2010.501754

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Journal Article] E1A, E1B double-restricted adenovirus enhances the cytotoxicity and antitumor activity of gemcitabine to renal cell carcinoma.2011

    • Author(s)
      Wang H, Satoh M, Chen GP, Li DC, Hamada H, Arai Y.
    • Journal Title

      CHINESE MEDICAL JOURNAL

      Volume: APR;124(7) Pages: 1082-1087

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Journal Article] Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts2011

    • Author(s)
      Takenouchi M, Hirai S, Sakuragi N, Yagita H, Hamada H, Kato K
    • Journal Title

      Clin Cancer Res

      Volume: 17(9) Pages: 2819-2829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Journal Article] Therapeutic time window of mesenchymal stem cells derived from bone marrow after cerebral ischemia2010

    • Author(s)
      Komatsu K, Honmou O, Suzuki J, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Brain Res

      Volume: 1334 Pages: 84-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia2010

    • Author(s)
      Zheng W, Honmou O, Miyata K, Harada K, Suzuki J, Liu H, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Brain Res

      Volume: 1310 Pages: 8-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia.2010

    • Author(s)
      Zheng W, Honmou O, Miyata K, Harada K, Suzuki J, Liu H, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Brain Res 1310

      Pages: 8-16

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic time window of mesenchymal stem cells derived from bone marrow after cerebral ischemia.2010

    • Author(s)
      Komatsu K, Honmou O, Suzuki J, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Brain Res 1334

      Pages: 84-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia.2009

    • Author(s)
      Toyama K, Honmou O, Harada K, Suzuki J, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Exp Neurol 216

      Pages: 47-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions2009

    • Author(s)
      Song CH, Honmou O, Ohsawa N, Nakamura K, Hamada H, Furuoka H, Hasebe R, Horiuchi M
    • Journal Title

      Journal of Virology

      Volume: 83 Pages: 5918-5927

    • NAID

      120001629752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia2009

    • Author(s)
      Toyama K, Honmou O, Harada K, Suzuki J, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      Exp Neurol

      Volume: 213 Pages: 47-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions.2009

    • Author(s)
      Song CH, Honmou O, Ohsawa N, Nakamura K, Hamada H, Furuoka H, Hasebe R, Horiuchi M
    • Journal Title

      Journal of Virology 83

      Pages: 5918-5927

    • NAID

      120001629752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Sendai viral vector mediated angiopoietin-1 gene transfer for experimental ischemic limb disease.2009

    • Author(s)
      Huang J, Inoue M, Hasegawa M, Tomihara K, Tanaka T, Chen J, Hamada H
    • Journal Title

      Angiogenesis 12(3)

      Pages: 243-249

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Therapeutic benefits by human mesenchymal stem cells (hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia.2008

    • Author(s)
      Onda T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      J Cereb Blood Flow Metab 28

      Pages: 329-340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits by human mesenchymal stem cells(hMSCs) and Ang-1 gene-modified hMSCs after cerebral ischemia2008

    • Author(s)
      Onda T, Honmou O, Harada K, Houkin K, Hamada H, Kocsis JD
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 28 Pages: 329-340

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390388
  • [Journal Article] Therapeutic benefits by Ang-1 gene-modified2008

    • Author(s)
      Onda, T., Honmou, O., Harada, K, Houkin, K., Hamada, H., Koosis, J.D
    • Journal Title

      human mesenchvmal stem cells after cerebral ischemia. Journal of Cerebral Blood Flow & Metabolism 28

      Pages: 329-340

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Gene transfer of CD40-ligand to dendritic cells stimulates interferon-gamma production to induce growth arrest and apoptosis of tumor cells2008

    • Author(s)
      Tomihara K, Kato K, Masuta Y, Nakamura K, Uchida H, Sasaki K, Tanaka T, Huang J, Hiratsuka H and Hamada H
    • Journal Title

      Gene Therapy 15

      Pages: 203-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Gene transfer of CD40-ligand to dendritic cells stimulates interferon-γproduction to induce growth arrest and apoptosis of tumor cells.2008

    • Author(s)
      Tomihara K, Kato K, Masuta Y, Nakamura K, Uchida H, Sasaki K, Tanaka T, Huang J, Hiratsuka H, Hamada H
    • Journal Title

      Gene Therapy 15

      Pages: 203-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Selective gene transfer into neurons via Na, K-ATPase beta1. Targeting gene transfer with monoclonal antibody and adenovirus vector.2008

    • Author(s)
      Ishii K, Nakamura K, Kawaguchi S, Li R, Hirai S, Sakuragi N, Wada T, Kato K, Yamashita T, Hamada H
    • Journal Title

      J. Gene Med. 10(6)

      Pages: 597-609

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Selective gene transfer into neurons via Na, K-ATPase beta 1 targeting gene transfer with monoclonal antibody and adenovirus2008

    • Author(s)
      Ishii, K., Nakamura, K., Kawaguchi, S., Li, R., Hirai, S., Sakuragi, N., Wada, T., Kato, K., Yamashita T., and Hamada, H
    • Journal Title

      J. Gene Med 10

      Pages: 597-209

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Metalloprotease inhibitors block release of soluble CD27 and enhance the immune stimulatory activity of chronic lymphocytic leukemia cells2007

    • Author(s)
      Kato K, Chu P, Takahashi S, Hamada H and Kipps TJ
    • Journal Title

      Exp Hematol 35

      Pages: 434-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers.2007

    • Author(s)
      Wakayama M, Abei M, Kawashima R, Seo E, Fukuda K, Uqai H, Murata T, Tanaka N, Hyodo I, Hamada H, Yokoyama K
    • Journal Title

      Clin. Cancer Res. 13(10)

      Pages: 3043-3050

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Exploration of target molecules for prostate cancer gene therapy2007

    • Author(s)
      Suzuki K, Nakamura K, Kato K, Hamada H and Tsukamoto T
    • Journal Title

      Prostate 67

      Pages: 1163-1173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Gene transfer of non-cleavable cell surface mutants of human CD154 induces the immune response and diminishes systemic inflammatory reactions2007

    • Author(s)
      Masuta Y, Kato K, Tomihara K, Nakamura K, Sasaki K, Takahashi S and Hamada H
    • Journal Title

      J Immunother 30

      Pages: 694-704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated anti-tumor effects against human carcinoma cells2007

    • Author(s)
      Tomihara K, Kato K, Masuta Y, Nakamura K, Tanaka T, Hiratsuka H and Hamada H
    • Journal Title

      Int J Cancer 120

      Pages: 1491-1498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK- mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Hamada H et al.
    • Journal Title

      Int J Cancer 120

      Pages: 1491-1498

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Kato K, Masuta Y, Nakamura K, Tanaka T, Hiratsuka H, Hamada H
    • Journal Title

      Int. J. Cancer 120(7)

      Pages: 1491-1498

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Mesenchymal stem cells derived from peripheral blood protects against ischemia2007

    • Author(s)
      Ukai, R., Honmou, O., Harada, K., Houkin, K, Hamada, H., Kocsis, J.D
    • Journal Title

      J Neurotrauma 24(3)

      Pages: 508-520

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Gene transfer of noncleavable cell surface mutants of human CD154 induces the immune response and diminishes systemic inflammatory reactions.2007

    • Author(s)
      Masuta Y, Kato K, Tomihara K, Nakamura K, Sasaki K, Takahashi S, Hamada H
    • Journal Title

      J. Immunother. 30(7)

      Pages: 694-704

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Targetting strategies by coupling of adenovirus vector and antibody for cancer gene therapy2007

    • Author(s)
      Tanaka T, Hamada H, Kuroki, M, Kato K, Kinugasa T, Shibaguchi H and Kuroki M
    • Journal Title

      Recent Development in Gene Therapy

      Pages: 319-326

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007

    • Author(s)
      Sano M.et al., Hamada H.
    • Journal Title

      Nature 446(7134)

      Pages: 444-448

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Hamada H.
    • Journal Title

      Int.J.Cancer 120(7)

      Pages: 1491-1498

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Metalloprotease inhibitors block release of soluble CD27 and enhance the immune stimulatory activity of chronic lymphocytic leukemia cells.2007

    • Author(s)
      Kato K, Hamada H et al.
    • Journal Title

      Exp Hematol 35

      Pages: 434-442

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007

    • Author(s)
      Sano M, Hamada H et al.
    • Journal Title

      Nature 446(7134)

      Pages: 444-448

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Tanaka T, Hamada H, et al.
    • Journal Title

      Int.J.Cancer 120(7)

      Pages: 1491-1498

    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload.2007

    • Author(s)
      Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I
    • Journal Title

      Nature 446(7134)

      Pages: 444-448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Gene transfer of the CD40- ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Hamada H et al.
    • Journal Title

      Int J Cancer 120

      Pages: 1491-1498

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Gene transfer of the CD40-ligand to human dendritic cells induces NK-mediated antitumor effects against human carcinoma cells.2007

    • Author(s)
      Tomihara K, Tanaka T, Hamada H, et al.
    • Journal Title

      Int. J. Cancer 120(7)

      Pages: 1491-1498

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Cancer-targeting gene therapy usingtropism-modified adenovirus2007

    • Author(s)
      Tanaka T, Kuroki M, Hamada H, Kato K, Kinugasa T, Shibaguchi H, Zao J and Kuroki M
    • Journal Title

      Anticancer Res 27

      Pages: 3679-3684

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Journal Article] Intravenous administration of glial cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in the adult rat.2006

    • Author(s)
      Horita Y, Hamada H et al.
    • Journal Title

      J Neurosci Res 84

      Pages: 1495-1504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region.2006

    • Author(s)
      Saito Y.et al., Hamada H.
    • Journal Title

      Cancer Gene Therapy 13

      Pages: 242-252

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Detailed characterization of the mouse glioma 261 tumor model for experimental ghoblastoma therapy.2006

    • Author(s)
      Szatmari T, Hamada H et al.
    • Journal Title

      Cancer Sci 97

      Pages: 546-553

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Intravenous administration of ghal cell line-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against iniurv in a cerebral ischemia model in the adult rat.2006

    • Author(s)
      Horita Y, Hamada H et al.
    • Journal Title

      J Neurosci Res 84

      Pages: 1495-1504

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy2006

    • Author(s)
      Szatmari T, Hamada H et al.
    • Journal Title

      Cancer Sci 97

      Pages: 546-553

    • NAID

      10018176511

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Neural differentiation potential of peripheral blood- and bone marrow-derived precursor cells2006

    • Author(s)
      Kim, S., Honmou, O., Kato, K., Nonaka, T., Houkin, K., Hamada, H., Kocsis, J.D
    • Journal Title

      Brain Research 1123, 19

      Pages: 27-33

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Neuroprotection by P1GF gene-modified human mesenchymal stem cells after cerehral ischaemia.2006

    • Author(s)
      Liu H, Hamada H et al.
    • Journal Title

      Brain 129

      Pages: 2734-2745

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Carcinoembryonic antigen targeted selective genetherapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006

    • Author(s)
      Tanaka T, Hamada H et al.
    • Journal Title

      Clinical Cancer Research 12

      Pages: 3803-3813

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006

    • Author(s)
      Tanaka T, Kuroki Ma, Hamada H, et al.
    • Journal Title

      Clin.Cancer Res. 12(12)

      Pages: 3803-3813

    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy.2006

    • Author(s)
      Szatm, aacute, ri T. et al., Hamada H.
    • Journal Title

      Cancer Science 97(6)

      Pages: 546-553

    • NAID

      10018176511

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Neural differentiation potential of peripheral blood-and bone-marrow-derived precursor cells.2006

    • Author(s)
      Kim S, Hamada H et al.
    • Journal Title

      Brain Res (Epub ahead of print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat2006

    • Author(s)
      Honma, T., Honmou, O., Iihoshi, S., Houkin, K., Hamada, H., Kocsis, J.D
    • Journal Title

      Exp Neurol 199

      Pages: 56-66

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Ex vivo large scale generation of human platelets from cord blood CD34+cells.2006

    • Author(s)
      Matsunaga T.et al., Hamada H.
    • Journal Title

      Stem Cells 24(12)

      Pages: 2877-2887

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Ex vivo expansion of G-CSF- mobilized peripheral blood CD133+ progenitor cells on coculture with human stromal cells.2006

    • Author(s)
      Kawano Y, Hamada H et al.
    • Journal Title

      Exp Hematol 34

      Pages: 150-158

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Carcinoembryonic antigen targeted selective genetherapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006

    • Author(s)
      Tanaka T.et al., Hamada H.
    • Journal Title

      Clinical Cancer Research 12(12)

      Pages: 3803-3813

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region..2006

    • Author(s)
      Saito Y, Hamada H et al.
    • Journal Title

      Cancer Gene Ther 13

      Pages: 242-252

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Ex vivo expansion of G-CSF-mobihzed peripheral blood CD133+ progenitor cells on coculture with human stromal cells.2006

    • Author(s)
      Kawano Y, Hamada H et al.
    • Journal Title

      Exp Hematol 34

      Pages: 150-158

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Carcinoembryonic antigen targeted selective genetherapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006

    • Author(s)
      Tanaka T, Huang J, Hirai S, Kuroki M, Watanabe N, Tomihara K, Kato K, Hamada H
    • Journal Title

      Clinical Cancer Research 12(12)

      Pages: 803-3813

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Neural differentiation potential of peripheral blood- and bone-marrow-denved precursor cells.2006

    • Author(s)
      Kim S, Hamada H et al.
    • Journal Title

      Brain Res Epub ahead of print

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Delivery of condensed DNA by liposomal non-viral gene delivery system into nucleus of dendritic cells.2006

    • Author(s)
      Nakamura T, Hamada H et al.
    • Journal Title

      Biol Pharm Bull 29

      Pages: 1290-1293

    • NAID

      110005602287

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Neuroprotection by P1GF gene- modified human mesenchymal stem cells after cerebral ischaemia.2006

    • Author(s)
      Liu H, Hamada H et al.
    • Journal Title

      Brain 129

      Pages: 2734-2745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Ex vivo large scale generation of human platelets from cord blood CD34+ cells.2006

    • Author(s)
      Matsunaga T, Hamada H et al.
    • Journal Title

      Stem Cells 24

      Pages: 2877-2887

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Oncolytic replication-competent adenovirus suppresses tumor angiogenesis through preserved E1A region.2006

    • Author(s)
      Saito Y, Hamada H et al.
    • Journal Title

      Cancer Gene Ther 13

      Pages: 242-252

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Carcinoembryonic antigen-targeted selective gene therapy for gastric cancer through FZ33 fiber-modified adenovirus vectors.2006

    • Author(s)
      Tanaka T, Kuroki Ma, Hamada H, et al.
    • Journal Title

      Clin. Cancer Res. 12(12)

      Pages: 3803-3813

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat.2006

    • Author(s)
      Honma T, Hamada H et al.
    • Journal Title

      Exp Neurol 199

      Pages: 56-66

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Oncolytic viral therapy by bladder instillation using an E1A, E1B double-restricted adenovirus in an orthotopic bladder cancer model.2006

    • Author(s)
      Wang H, Hamada H et al.
    • Journal Title

      Urology 68

      Pages: 674-681

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] CEA-targeted Selective Gene Therapy for Gastric Cancer Through FZ33 Fiber Modified Adenovirus Vectors.2006

    • Author(s)
      Tanaka T, Jianhua Huang, Hirai S, Kuroki Mo, Kuroki Ma, Watanabe N, Tomihara K, Kato K, Hamada H
    • Journal Title

      Clin Can Res. (in press)

    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischemia2006

    • Author(s)
      Liu, H., Honmou, O., Harada, K., Nakamura, K., Houkin, K., Hamada, H., Kocsis, J.D
    • Journal Title

      BRAIN 129

      Pages: 2734-2745

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Intravenous administration of GDNF gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat2006

    • Author(s)
      Horita, Y., Honmou, O., Harada, K., Houkin, K., Hamada, H., Kocsis, J.D
    • Journal Title

      J.Neuroscience Research 84

      Pages: 1495-1504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner.2005

    • Author(s)
      Linwong W, Hamada H et al.
    • Journal Title

      Br J Pharmacol 145

      Pages: 818-828

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Neurorescue effects of VEGF on a rat model of Parkinson's disease.2005

    • Author(s)
      Yasuhara T, Hamada H et al.
    • Journal Title

      Brain Res Brain Res 1053

      Pages: 10-18

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.2005

    • Author(s)
      Sato Y.et al., Hamada H.
    • Journal Title

      Blood 106(2)

      Pages: 756-763

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank..2005

    • Author(s)
      Ugai H, Hamada H et al.
    • Journal Title

      J Gene Med 7

      Pages: 1148-1157

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotect : ve and angiogenic effects on focal cerebral ischemia.2005

    • Author(s)
      Yano A, Hamada H et al.
    • Journal Title

      J Neurosurg 103

      Pages: 104-114

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Inhibition of the antigen- induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner.2005

    • Author(s)
      Linwong, W, Hamada H et al.
    • Journal Title

      Br J Pharmacol 145

      Pages: 818-828

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Dual effects of adenovirus-mediated thrombopoietin gene transfer on hepatic oval cell proliferation and platelet counts.2005

    • Author(s)
      Ichiba M, Hamada H et al.
    • Journal Title

      Biochem Biophys Res Coramun 335

      Pages: 723-729

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Bc1-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J, Tanaka T, Hamada H, et al.
    • Journal Title

      Circulation 112(1)

      Pages: 76-83

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005

    • Author(s)
      Kurozumi K, Nakamura K, Tamiya T, Kawano Y, Ishii K, Kobune M, Hirai S, Uchida H, Sasaki K, Ito Y, Kato K, Honmou O, Houkin K, Date I, Hamada H
    • Journal Title

      Mol. Ther. 11(1)

      Pages: 96-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Dual effects of adenovirus- mediated thrombopoietin gene transfer on hepatic oval cell proliferation and platelet counts.2005

    • Author(s)
      Ichiba M, Hamada H et al.
    • Journal Title

      Biochem Biophys Res Commun 335

      Pages: 723-729

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Enhanced brain angiogenesis in chronic cerebral hypoperfusion after administration of plasmid human vascular endothehal growth factor in combination with indirect vasoreconstructive surgery.2005

    • Author(s)
      Kusaka N, Hamada H et al.
    • Journal Title

      J Neurosurg 103

      Pages: 882-890

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber-mutant adenoviral BMP2 gene.2005

    • Author(s)
      Tsuda H.et al., Hamada H.
    • Journal Title

      J Gene Med. 7(10)

      Pages: 1322-1334

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Effective gene therapy of biliary tract cancers by a conditionally rephcative adenovirus expressing uracil phosphonbosyltransferase significance of timing of 5-fluorouracil administration.2005

    • Author(s)
      Seo E, Hamada H et al.
    • Journal Title

      Cancer Res 65

      Pages: 546-552

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy.2005

    • Author(s)
      Hamada H, Niitsu Y et al.
    • Journal Title

      Cancer Sci 96

      Pages: 149-156

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model2005

    • Author(s)
      Kurosumi, K., Nakaniura, K., Tamiya, T., Kawano, Y., Kobune, M., Hirai, S., Uchida, H., Sasaki, K., Ito, Y., Kato, K.,Honmou, O., Houkin, K., Date, I., Hamada, H
    • Journal Title

      Mol. Ther 11(1)

      Pages: 96-104

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Intravenous infusion of BDNF gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat2005

    • Author(s)
      Nomura, T., Honmou, O., Harada, H., Houkin, K., Hamada, H., Kocsis, J.D
    • Journal Title

      Neuroscience 136

      Pages: 161-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Expansion of CD34+ cells on telomenzed human stromal cells without losing erythroid-differentiation potential in a serum-free condition.2005

    • Author(s)
      Kobune M, Hamada H et al.
    • Journal Title

      Int J Hematol 81

      Pages: 18-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005

    • Author(s)
      Kurozumi K, Hamada H et al.
    • Journal Title

      Mol Ther 1

      Pages: 96-104

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase : significance of timing of 5-fluorouracil administration..2005

    • Author(s)
      Seo E, Hamada H et al.
    • Journal Title

      Cancer Res 65

      Pages: 546-552

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J, Nakamura K, Ito Y, Uzuka T, Morikawa M, Hirai S, Tomihara K, Tanaka T, Masuta Y, Ishii K, Kato K, Hamada H
    • Journal Title

      Circulation 112(1)

      Pages: 76-83

    • Data Source
      KAKENHI-PROJECT-17591421
  • [Journal Article] Matsunaga T and Niitsu Y. Mesenchymal stem cells (MSC) as therapeutic cytoreagents for gene therapy.2005

    • Author(s)
      Hamada H. et al.
    • Journal Title

      Cancer Science, (Review) (in press)

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Telomenzed human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.2005

    • Author(s)
      Kobune M, Hamada H et al.
    • Journal Title

      Exp Hematol 33

      Pages: 1544-1553

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells as therapeutic cytoreagents for gene therapy2005

    • Author(s)
      Hamada, H., et al.
    • Journal Title

      Cancer Sci (In press)

    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Bcl-xL transfer inhibits Bax translocation and prologs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J.et al., Hamada H.
    • Journal Title

      Circulation (in press)

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold reservation time in rat.2005

    • Author(s)
      Huang J.et al., Hamada H.
    • Journal Title

      Circulation 112(1)

      Pages: 76-83

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Adenovirus-mediated gene transfer of caspase-8 sensitizes human adenocarcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand.2005

    • Author(s)
      Yasui H, Hamada H et al.
    • Journal Title

      Int J Oncol 26

      Pages: 537-544

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005

    • Author(s)
      Kurozumi K.et al., Hamada H.
    • Journal Title

      Mol Ther. 11(1)

      Pages: 96-104

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] ElB-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis.2005

    • Author(s)
      Harada N, Hamada H et al.
    • Journal Title

      Oncol Rep 14

      Pages: 1155-1163

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Neurorescue effects of VEGF on a rat mod el of Parkinson's disease.2005

    • Author(s)
      Yasuhara T, Hamada H et al.
    • Journal Title

      Brain Res Brain Res 1053

      Pages: 10-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.2005

    • Author(s)
      Sato Y, Hamada H et al.
    • Journal Title

      Blood 106

      Pages: 756-763

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model.2005

    • Author(s)
      Kurozumi K.et al., Hamada H.
    • Journal Title

      Mol.Ther. 11(1)

      Pages: 96-104

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J, Hamada H et al.
    • Journal Title

      Circulation 112

      Pages: 76-83

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase: significance of timing of 5-fluorouracil administration.2005

    • Author(s)
      Seo E, Abei M, Wakayama M, Fukuda K, Ugai H, Murata T, Todoroki T, Matsuzaki Y, Tanaka N, Hamada H, Yokoyama K
    • Journal Title

      Cancer Res. 65(2)

      Pages: 546-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Purification of infectious adenovirus in two hours by ultracentnfugation and tangential flow filtration.2005

    • Author(s)
      Ugai H, Hamada H et al.
    • Journal Title

      Biochem Biophys Res Commun 331

      Pages: 1053-1060

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Effective gene therapy of biliary tract cancers by a conditionally replicative adenovirus expressing uracil phosphoribosyltransferase : significance of timing of 5-fluorouracil administration.2005

    • Author(s)
      Seo E.et al., Hamada H.
    • Journal Title

      Cancer Res. 65(2)

      Pages: 546-552

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] A database of recombinant viruses and recombinant viral vectors available from the RIKEN DNA bank.2005

    • Author(s)
      Ugai H, Hamada H et al.
    • Journal Title

      J Gene Med 7

      Pages: 1148-1157

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Encapsulated vascular endothelial growth factor-secreting cell grafts have neuroprotective and angiogenic effects on focal cerebral ischemia.2005

    • Author(s)
      Yano A, Hamada H et al.
    • Journal Title

      J Neurosurg 103

      Pages: 104-114

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] I.v. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat.2005

    • Author(s)
      Nomura T, Hamada H et al.
    • Journal Title

      Neuroscience 136

      Pages: 161-169

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Mesenchymal stem cells as therapeutic cytoreagents for gene therapy2005

    • Author(s)
      Hamada, H., et al.
    • Journal Title

      Cancer Sci 96

      Pages: 149-156

    • Data Source
      KAKENHI-PROJECT-16390414
  • [Journal Article] Enhanced brain angiogenesis in chronic cerebral hypoperfusion after administration of plasmid human vascular endothelial growth factor in combination with indirect vasoreconstructive surgery.2005

    • Author(s)
      Kusaka N, Hamada H et al.
    • Journal Title

      J Neurosurg 103

      Pages: 882-890

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber-mutant adenoviral BMP2 gene.2005

    • Author(s)
      Tsuda H, Hamada H et al.
    • Journal Title

      J Gene Med 7

      Pages: 1322-1334

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] E1B-deleted adenovirus replicates in p53-deficient lung cancer cells due to the absence of apoptosis.2005

    • Author(s)
      Harada, Hamada H et al.
    • Journal Title

      Oncol Rep 14

      Pages: 1155-1163

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid-differentiation potential in a serum-free condition.2005

    • Author(s)
      Kobune M.et al., Hamada H.
    • Journal Title

      Int J Hematol. 81(1)

      Pages: 18-25

    • NAID

      10014282469

    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat.2005

    • Author(s)
      Nomura T, Hamada H et al. I.v.
    • Journal Title

      Neuroscience 136

      Pages: 161-169

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] The differences between high and low-dose administration of VEGF to dopaminergic neurons of in vitro and in vivo Parkinson's disease model.2005

    • Author(s)
      Yasuhara T, Hamada H et al.
    • Journal Title

      Brain Res 1038

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Purification of infectious adenovirus in two hours by ultracentrifugation and tangential flow filtration.2005

    • Author(s)
      Ugai H, Hamada H et al.
    • Journal Title

      Biochem Biophys Res Commun 331

      Pages: 1053-1060

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Accumulation of infectious mutants in stocks during the propagation of fiber-modified recombinant adenoviruses.2005

    • Author(s)
      Ugai H, Hamada H et al.
    • Journal Title

      Biochem Biophys Res Commun 337

      Pages: 806-814

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Expansion of CD34+ cells on telomerized human stromal cells without losing erythroid- differentiation potential in a serum-free condition.2005

    • Author(s)
      Kobune M, Hamada H et al.
    • Journal Title

      Int J Hematol 81

      Pages: 18-25

    • NAID

      10014282469

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Enhanced osteoinduction by mesenchymal stem cells transfected with a fiber-mutant adenoviral BMP2 gene.2005

    • Author(s)
      Tsuda H, Wada T, Yamashita T, Hamada H
    • Journal Title

      J. Gene Med. 7(10)

      Pages: 1322-1334

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Bcl-xL gene transfer inhibits Box translocation and prolongs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J, Hamada H et al.
    • Journal Title

      Circulation 112

      Pages: 76-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Bcl-xL gene transfer inhibits Bax translocation and prolongs cardiac cold preservation time in rat.2005

    • Author(s)
      Huang J, Nakamura K, Ito Y, Uzuka T, Morikawa M, Hirai S, Tomihara K, Tanaka T, Masuta Y, Ishii K, Kato K, Hamada H
    • Journal Title

      Circulation 112(1)

      Pages: 76-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Journal Article] Conduction performance of collateral vessels induced by vascular endothehal growth factor or basic fibroblast growth factor.2004

    • Author(s)
      Kondoh K, Hamada H et al.
    • Journal Title

      Cardiovasc Res 61

      Pages: 132-142

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Conduction performance of collateral vessels induced by vascular endothelial growth factor or basic fibroblast growth factor.2004

    • Author(s)
      Kondoh K, Hamada H et al.
    • Journal Title

      Cardiovasc Res 61

      Pages: 132-142

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Wnt3 modulates the characteristics and cobblestone area-supporting activity of human stromal cells.2004

    • Author(s)
      Chiba H, Hamada H et al.
    • Journal Title

      Exp Hematol 232

      Pages: 1194-1203

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Apoptosis induction with 5-fluorocytosine/cytosine deaminase gene therapy for human malignant ghoma cells mediated by adenovirus.2004

    • Author(s)
      Kurozumi K, Hamada H et al.
    • Journal Title

      J Neurooncol 66

      Pages: 117-127

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan clinical and immunological findings.2004

    • Author(s)
      Tani K, Hamada H et al.
    • Journal Title

      Mol Ther 10

      Pages: 799-816

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV- tk suicide gene : therapy in vitro and in vivo.2004

    • Author(s)
      Okada T, Hamada H et al.
    • Journal Title

      J Gene Med 6

      Pages: 288-299

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Appropriate control of ex vivo gene therapy delivering basic fibroblast growth factor promotes successful and safe development of collateral vessels in rabbit model of hind limb ischemia.2004

    • Author(s)
      shu S, Hamada H et al.
    • Journal Title

      J Vase Surg 39

      Pages: 629-638

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Combination of porous hydroxyapatite and cationic liposomes as a vector for BMP-2 gene therapy.2004

    • Author(s)
      Ono I, Hamada H et al.
    • Journal Title

      Biomaterials 25

      Pages: 4709-4718

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of rephcable E1B-55K-deleted adenovirus with E1A expressed by CEA promoter.2004

    • Author(s)
      Sagawa T, Hamada H et al.
    • Journal Title

      Mol Ther 10

      Pages: 1043-1050

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] In vivo electroporation enhances plasmid-based gene transfer of basic fibroblast growth factor for the treatment of ischemic limb.2004

    • Author(s)
      Nishikage S, Hamada H et al.
    • Journal Title

      J Surg Res 120

      Pages: 37-46

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Appropriate control of ex vivo gene therapy delivering basic fibroblast growth factor promotes successful and safe development of collateral vessels in rabbit mod, A of hind limb ischemia2004

    • Author(s)
      Ishii S, Hamada H et al.
    • Journal Title

      J Vasc Surg 39

      Pages: 629-638

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] In situ generation of pseudotyped retroviral progeny by adenovirus-mediated transduction of tumor cells enhances the killing effect of HSV-tk suicide gene therapy in vitro and in vivo.2004

    • Author(s)
      Okada T, Hamada H et al.
    • Journal Title

      J Gene Med 6

      Pages: 288-299

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model.2004

    • Author(s)
      Kurozumi K.et al., Hamada H.
    • Journal Title

      Mol.Ther. 9(2)

      Pages: 189-197

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Adenovirus-Mediated Transfer of siRNA against Survivin Induced Apoptosis and Attenuated Tumor Cell Growth in Vitro and in Vivo.2004

    • Author(s)
      Uchida H.et al., Hamada H.
    • Journal Title

      Mol.Ther. 10(1)

      Pages: 162-171

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Transduction of soluble Flt-1 gene to peritoneal mesothelial cells can effectively suppress peritoneal metastasis of gastric cancer2004

    • Author(s)
      Sako A, Hamada H et al.
    • Journal Title

      Cancer Res 64

      Pages: 3624-3628

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease.2004

    • Author(s)
      Yasuhara T, Hamada H et al.
    • Journal Title

      Eur J Neurosci 19

      Pages: 1494-1504

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta-2m-/- repopulating cells.2004

    • Author(s)
      Kobune M, Hamada H et al.
    • Journal Title

      Blood 104

      Pages: 1002-1009

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Local administration of hepatocyte growth factor gene enhances the regeneration of dermis in acute incisional wounds.2004

    • Author(s)
      Ono I, Hamada H et al.
    • Journal Title

      J Surg Res 120

      Pages: 47-55

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model.2004

    • Author(s)
      Kurozumi K, Hamada H et al.
    • Journal Title

      Mol Ther 9

      Pages: 189-197

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] BDNF gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model.2004

    • Author(s)
      Kurozumi K, Hamada H et al.
    • Journal Title

      Vol Ther 9

      Pages: 189-197

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Anti-tumor effect of genetically engineered mesenchymal stem cells in a rat glioma model.2004

    • Author(s)
      Nakamura K, Hamada H et al.
    • Journal Title

      Gene Ther 11

      Pages: 1155-1164

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Indian hedgehog gene transfer augments hematopoietic support of human stromal cells including NOD/SCID-beta-2m-/-repopulating cells.2004

    • Author(s)
      Kobune M.Hamada H et al.
    • Journal Title

      Blood 104

      Pages: 1002-1009

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Anti-tumor effect of genetically engineered mesenchymal stem cells in a rat ghoma model.2004

    • Author(s)
      Nakamura K, Hamada H et al.
    • Journal Title

      Gene Ther 11

      Pages: 1155-1164

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Combined administration of basic fibroblast growth factor protein and the hepatocyte growth factor gene er hances the regeneration of dermis in acute incisional wounds.2004

    • Author(s)
      Ono I, Hamada H et al.
    • Journal Title

      Wound Repair Regen 12

      Pages: 67-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Anti-tumor effect of genetically engineered mesenchymal stem cells in a rat glioma model.2004

    • Author(s)
      Kurozumi K.et al., Hamada H.
    • Journal Title

      Gene Ther. 11(14)

      Pages: 1155-1164

    • Data Source
      KAKENHI-PROJECT-12217123
  • [Journal Article] Prolonged survival of mice with multiple liver metastases of human colon cancer by intravenous administration of replicable E1B-55K-deleted adenovirus with ElA expressed by CEA promoter.2004

    • Author(s)
      Sagawa T, Hamada H et al.
    • Journal Title

      Mol Ther 10

      Pages: 1043-1050

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Combined administration of basic fibroblast growth factor protein and the hepatocyte growth factor gene enhances the regeneration of dermis in acute mcisional wounds.2004

    • Author(s)
      Ono I, Hamada H et al.
    • Journal Title

      Wound Repair Regen 12

      Pages: 67-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Phase I study of autologous tumor vaccines trar sduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan : clinical and immunological findings.2004

    • Author(s)
      Tani K, Hamada H et al.
    • Journal Title

      Mol Ther 10

      Pages: 799-816

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Apoptosis induction with 5- fluorocytosine /cytosine deaminase gene therapy for human malignant glioma cells mediated by adenovirus.2004

    • Author(s)
      Kurozumi K, Hamada H et al.
    • Journal Title

      J Neurooncol 66

      Pages: 117-127

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Adenovirus-Mediated Transfer of siRNA against Survivin Induced Apoptosis and Attenuated Tumor Cell Growth in Vitro and in Vivo.2004

    • Author(s)
      Uchida H, Hamada H et al.
    • Journal Title

      Mol Ther 10

      Pages: 162-171

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Transduction of soluble Flt-1 gene to peritoneal mesothehal cells can effectively suppress peritoneal metastasis of gastric cancer.2004

    • Author(s)
      Sako A, Hamada H et al.
    • Journal Title

      Cancer Res 64

      Pages: 3624-3628

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Journal Article] Conduction performance of collateral vessels induced by vascular endothelial growth factor or basic fibroblast growth factor.2003

    • Author(s)
      Kondoh K, Koyama H, Mi yata T, Takato T, Hamada H, Shigematsu H.
    • Journal Title

      Cardiovascular Research (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Exvivo gene transfer of basic fibroblast growth factor improves cardiac function and blood flow in a swine chronic myocardial ischemia model2003

    • Author(s)
      Ninomiya M, Koyama H, Miyata T, Hamada H, Miyatake S, Shigematsu H, Takamoto S.
    • Journal Title

      Gene Therapy 10

      Pages: 1152-1160

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Appropriate control of ex vivo gene therapy delivering basic fibroblast growth factor promotes successful and safe development of collateral vessels in rabbit model of hind limb ischemia2003

    • Author(s)
      Ishii S, Koyama H, Miyata T, Nishikage S, Hamada H, Miyatake S, Shigematsu H
    • Journal Title

      Journal of Vascular Surgery (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Conduction performance of collateral vessels induced by vascular endothelial growth factor or basicfibroblast growth factor.2003

    • Author(s)
      Kondoh K, Koyama H, Miyata T, Takato T, Hamada H, Shigematsu H
    • Journal Title

      Cardiovascular Research (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Ex vivo gene transfer of basic fibroblast growth factor improves cardiac function and blood flow in a swine chronic myocardial ischemia model2003

    • Author(s)
      Ninomiya M, Koyama H, Miyata T, Hamada H, Miyatake S, Shigematsu H, Takamoto S
    • Journal Title

      Gene Therapy 10

      Pages: 1152-1160

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Appropriate control of ex vivo gene therapy delivering basic fibroblast growth factor promotes successful and safe development of collateral vessels in rabbit model of hind I imbischemia.2003

    • Author(s)
      Ishii S, Koyama H, Miyata T, Nishikage S, Hamada H, Miyatake S, Shigematsu H.
    • Journal Title

      Journal of Vascular Surgery (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12470236
  • [Journal Article] Telomerized human bone marrow-derived cell clones maintain the phenotype of hematopoietic-supporting osteoblastic and myofibroblastic stromal cells after long-term culture.

    • Author(s)
      Kobune M, Hamada H et al.
    • Journal Title

      EXP Hematol 33

      Pages: 1544-1553

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16209034
  • [Patent] 抗Trop-2 抗体2011

    • Inventor(s)
      山口美樹、加藤和則、濱田洋文、他
    • Industrial Property Rights Holder
      札幌医科大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Patent] IL-13Ra2に対する抗体およびこれを含む診断・治療薬2009

    • Inventor(s)
      濱田洋文、加藤和則、中村公則
    • Industrial Property Rights Holder
      札幌医大
    • Industrial Property Number
      2007-147478
    • Filing Date
      2009-06-01
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] IL13Ra2に対する抗体およびこれを含む診断・治療薬2008

    • Inventor(s)
      濱田洋文加藤和則中村公則
    • Industrial Property Rights Holder
      札幌医科大学
    • Filing Date
      2008-05-30
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2008

    • Inventor(s)
      濱田洋文、加藤和則、中村公則
    • Industrial Property Rights Holder
      札幌医大
    • Acquisition Date
      2008-03-21
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2008

    • Inventor(s)
      濱田 加藤 中村
    • Industrial Property Rights Holder
      札幌医大
    • Acquisition Date
      2008-03-21
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] 抗CEA抗体を用いた標的化遺伝子治療2007

    • Inventor(s)
      濱田洋文、田中俊裕、加藤和則, ら
    • Industrial Property Rights Holder
      札幌医大
    • Industrial Property Number
      2005-208800
    • Filing Date
      2007-07-19
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2007

    • Inventor(s)
      濱田 加藤 中村
    • Industrial Property Rights Holder
      札幌医大
    • Filing Date
      2007-12-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] PAP2aに対する抗体ならびにその診断的および治療的使用2006

    • Inventor(s)
      濱田, 加藤, 中村
    • Industrial Property Rights Holder
      北海道
    • Filing Date
      2006
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Patent] PAP2aに対する抗体ならびにその診断的および治療的応用

    • Inventor(s)
      濱田洋文、加藤和則、中村公則
    • Industrial Property Rights Holder
      札幌医科大学
    • Overseas
    • Data Source
      KAKENHI-PROJECT-19390157
  • [Presentation] Application of in-house monoclonal antibody resources to a fully retargeted oncolytic herpes simplex virus platform2013

    • Author(s)
      Yu Okubo1, Takuma Suzuki1, Tomoko Shibata1, Mao Komai1, Takeshi Fukuhara1, Miki Yamaguchi2, Sachie Hirai2, Yoshitaka Miyagawa3, Justus B. Cohen3, Joseph C. Glorioso3, Hirofumi Hamada1, and Hiroaki Uchida1
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Establishment of highly functional monoclonal antibodies through novel screening methods for targeted cancer therapy2013

    • Author(s)
      Moegi Sato1, Miki Yamaguchi2, Hitomi Ikeda1, Yuta Matsuura1, Takeshi Fukuhara1, Hirofumi Hamada1, and Hiroaki Uchida1
    • Organizer
      第81回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Generation of Immunotoxins against AML: Cytocidal activities with anti-CD71 mAb2013

    • Author(s)
      Yukari Nishii1, Miki Yamaguchi1, Hirofumi Hamada1,2
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Application of monoclonal antibody resources to a fully retargeted HSV platform2013

    • Author(s)
      Tomoko Shibata1, Takuma Suzuki1, Yu Okubo1, Mao Komai1, Takeshi Fukuhara1, Miki Yamaguchi2, Sachie Hirai2, Yoshitaka Miyagawa3, Justus B. Cohen3, Joseph C. Glorioso3, Hirofumi Hamada1, and Hiroaki Uchida1
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Development of fully retargeted oncolytic herpes simplex virus vectors by insertion of tumor-specific single-chain antibodies into viral envelope glycoprotein D2013

    • Author(s)
      Takuma Suzuki1, Tomoko Shibata1, Yu Okubo1, Takeshi Fukuhara1, Yoshitaka Miyagawa2, Justus B. Cohen2, Joseph C. Glorioso2, Kenji Nakano3, Izumi Kumagai4, Masahide Kuroki5, Miki Yamaguchi6, Sachie Hirai6, Hirofumi Hamada1, and Hiroaki Uchida1
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] 白血病/リンパ腫に対するスーパー標的化抗体を用いたイムノトキシンの開発2013

    • Author(s)
      西井ゆかり、山口美樹、平井幸恵、内田宏昭、濱田洋
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2013-10-03
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Generation of immunotoxins with super-targeting mAb in the leukemia/lymphoma2013

    • Author(s)
      Yukari Nishii1, Miki Yamaguchi1, Hiroaki Uchida2, Hirofumi Hamada1,2
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Generation of immunotoxins with super-targeting mAb in acute myeloid leukemia2013

    • Author(s)
      Miki Yamaguchi1, Yukari Nishii1, Hirofumi Hamada1,2
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] 急性骨髄性白血病に対するスーパー標的化抗体を用いたイミュノトキシンの開発2013

    • Author(s)
      山口美樹、西井ゆかり、濱田洋文
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] スーパー標的化抗体を用いたimmunotoxin の開発:AML に対する抗CD71 抗体を用いた抗腫瘍活性2012

    • Author(s)
      西井ゆかり、山口美樹、平井幸恵、濱田洋文
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-20
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Efficacy and safety of oncolytic adenovirus combined with UPRT/5-FU suicide gene system: Evaluation in syngenic pancreas cancer model in immunocompetent,adenovirus-permissive Syrian hamsters.2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,Kawashima R,Seo E, WakayamaM, Hamada H, Yokoyama KK, Obata Y, Hyodo I
    • Organizer
      第18回日本遺伝子治療学会総会
    • Place of Presentation
      熊本テルサ,熊本
    • Year and Date
      2012-06-29
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] メラノーマ標的化新規モノクローナル抗体の網羅的解析2012

    • Author(s)
      平井幸恵、山口美樹、濱田洋文
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Year and Date
      2012-09-19
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Systematic screening of novel monoclonal antibodies targeting human melanoma cells2012

    • Author(s)
      Hirai S, Yamaguchi M, Hamada H
    • Organizer
      The 71st Annual Meeting of Japanese Cancer Association
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Efficacy and safety of gene-chemo therapy using oncolytic adenovirus expressing uracil phosphoribosyl transferase (UPRT) followed by 5-fluorouracil administration in syngenic pancreatic and biliary cancers in immunocompetent adenoviruspermissive Syrian ha2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,SeoE, Wakayama M, KawashimaR, Murata T, Hamada H, YokoyamaKK, Obata Y, Hyodo I.
    • Organizer
      第15回米国遺伝子・細胞治療学会
    • Place of Presentation
      ペンシルベニア・コンベンションセンター,フィラデルフィア,アメリカ合衆国
    • Year and Date
      2012-05-17
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] Generation of immunotoxins with super-targeting mAb: superior antitumor activities with anti-CD71 mAb agenst AML2012

    • Author(s)
      Nishii Y, Yamaguchi M, Hirai S, Hamada H
    • Organizer
      The 71st Annual Meeting of Japanese Cancer Association
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Immunosuppression enhances the Efficacy of oncolytic adenovirus-mediated uracil phosphoribosyl Transferase (UPRT)/ 5-fluorouracil suicide gene therapy in immunocompetent adenoviruspermissive Syrian hamsters2012

    • Author(s)
      Hasegawa N, Abei M, Fukuda K,Seo E,Wakayama M, Kawashima R, Hamada H, Yokoyama KK, Obata Y, Hyodo I
    • Organizer
      2012国際癌遺伝子・細胞治療学会(ISCGT)
    • Place of Presentation
      フラマホテル,シンガポール
    • Year and Date
      2012-10-04
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] スーパー標的化抗体を用いたImmunotoxin の開発:非小細胞肺癌に対するCD59 抗体を用いた抗腫瘍活性2011

    • Author(s)
      山口美樹、西井ゆかり、平井幸恵、濱田洋文
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] メラノーマに対する新規標的化抗体の樹立と機能解析2011

    • Author(s)
      平井幸恵、山口美樹、濱田洋文
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] EpCAM and EGFR-targeted selective gene therapy for biliary cancers using Z33-fiber modified adenovirus.2010

    • Author(s)
      Abei M, Kawashima R, Fukuda K, Nakamura K, Murata T,Yokoyama KK,Hamada H, Hyodo I
    • Organizer
      第16回日本遺伝子治療学会総会
    • Place of Presentation
      栃木県総合文化センター,宇都宮
    • Year and Date
      2010-07-02
    • Data Source
      KAKENHI-PROJECT-22590755
  • [Presentation] 腫瘍標的遺伝子治療2009

    • Author(s)
      濱田洋文
    • Organizer
      第68回日本癌学会学術総会教育講演モーニングレクチャー
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Presentation] 膵がんに対する遺伝子治療の展望2009

    • Author(s)
      濱田洋文
    • Organizer
      第68回日本癌学会学術総会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Presentation] 腫瘍の特異的標的化を目指した遺伝子治療法の開発2008

    • Author(s)
      濱田洋文
    • Organizer
      第3次対がん10か年総合戦略、第2回合同シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Presentation] 臓器がん-膵癌「新たな膵癌抗原の探索」2006

    • Author(s)
      濱田洋文
    • Organizer
      日本癌学会総会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2006-09-30
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Presentation] 遺伝子治療現状と近未来腫瘍の標的化を目指した遺伝子治療の開発2005

    • Author(s)
      濱田洋文
    • Organizer
      日本癌学会総会教育講演
    • Place of Presentation
      札幌
    • Year and Date
      2005-09-16
    • Data Source
      KAKENHI-PROJECT-17016059
  • [Presentation] Intravenous administration of immortalized human mesenchymal stem cells repairs the ischemic leisions in the rat middle cerebral artery occulusion model2004

    • Author(s)
      Honmou, O., Iihoshi, S., Honma, T., Harada, K., Hamada, H., Houkin K., Kocsis, JD
    • Organizer
      34th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      San Diego
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390414
  • [Presentation] Generation of immunotoxins with super-targeting mAb: superior antitumor activities with anti-TROP2 mAb against NSCLC

    • Author(s)
      山口美樹、西井ゆかり、平井幸恵、加藤和則、濱田洋文
    • Organizer
      第15回日本がん免疫学会総会
    • Place of Presentation
      大阪府
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] メラノーマに対する新規標的化抗体の樹立と機能解析

    • Author(s)
      平井幸恵、山口美樹、濱田洋文
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PROJECT-23501309
  • [Presentation] Generation of immunotoxins with super-targeting monoclonal antibodies (mAb): superior antitumor activities with anti-CD59 mAb against non-small cell lung cancers (NSCLC).

    • Author(s)
      山口美樹、西井ゆかり、平井幸恵、濱田洋文
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PROJECT-23501309
  • 1.  HONMOU Osamu (90285007)
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  • 3.  HIRAKAWA Kimiyoshi (00010166)
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  • 4.  AOYAGI Masaru (40134704)
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  • 5.  SUNAMURA Makoto (10201584)
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  • 6.  MIYATA Tetsuro (70190791)
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  • 7.  HOUKIN Kiyohiro (90229146)
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  • 37.  脇本 浩明 (30270507)
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  • 42.  UCHIDA Hiroaki (20401250)
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  • 43.  YAMAGUCHI Nobuo (90012723)
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  • 45.  TAKAHASHI Takashi (50231395)
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  • 46.  TANIGUCHI Naoyuki (90002188)
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  • 77.  KOMEDA Kajuro (90074533)
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  • 78.  SASAGURI Yasuyuki (60140646)
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  • 79.  MATSUDA Takehisa (60142189)
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  • 80.  OSHIRO Hidemi (80272558)
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  • 81.  SAIDA Toshiaki (10010381)
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  • 90.  SHIGEMATSU Kunihiro (20215966)
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  • 123.  村上 洋太 (20260622)
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  • 124.  西村 善文 (70107390)
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  • 125.  畠山 昌則 (40189551)
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  • 126.  永田 宏次 (30280788)
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  • 127.  中畑 龍俊 (20110744)
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  • 128.  永井 義之 (20022874)
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  • 131.  仙波 憲太郎 (70206663)
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  • 132.  川畑 正博 (60224838)
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  • 133.  垣塚 彰 (80204329)
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  • 134.  矢守 隆夫 (60200854)
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  • 135.  吉田 純 (40158449)
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  • 136.  成宮 周 (70144350)
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  • 137.  中村 祐輔 (70217909)
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  • 138.  月田 承一郎 (50155347)
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  • 139.  谷口 維紹 (50133616)
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  • 140.  竹縄 忠臣 (40101315)
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  • 141.  曽根 三郎 (40145024)
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  • 142.  浅野 茂隆 (50134614)
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  • 143.  小針 雅男 (30170369)
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  • 144.  振津 琢磨 (20315526)
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  • 145.  北川 剛 (90262021)
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  • 146.  轟 健 (70114105)
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  • 147.  TSUKUMA Hideaki
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    # of Collaborated Products: 0 results
  • 148.  中村 佳子
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  • 149.  寳金 清博
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    # of Collaborated Products: 17 results
  • 150.  阿部井 誠人
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