Okumura Ko 奥村康

… Alternative Names

OKUMURA Ko 奥村康

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Researcher Number	50009700
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 順天堂大学, 医学部, 特任教授 2017: 順天堂大学, 医学研究科, 特任教授 2016 – 2017: 順天堂大学, 医学部, 特任教授 2013 – 2016: 順天堂大学, 医学部, 教授 2008 – 2012: 順天堂大学, 医学部, 特任教授 … More 2010: Juntendo University, 大学院・医学研究科, 特任教授 2008: Juntendo University, 医学部, 准教授 2004 – 2007: 順天堂大学, 医学部, 教授 1986 – 2002: 順天堂大学, 医学部, 教授 2001: 順天堂大, 医学部, 教授 1994: 順天堂大, 医学部, 教授 1992: 順天堂大, 医, 教授 1990: 順天堂大学, 医学部・免疫学, 教授 1988: 順天堂大学, 医学部免疫学研究室, 教授 1986: 順天堂大, 医学部, 教授 1985: 順天堂大学, 医, 教授 Less
Review Section/Research Field	Principal Investigator Immunology / 膠原病・アレルギー・感染症内科学 / Experimental pathology / Immunology / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Biological Sciences Except Principal Investigator Immunology / 内科学一般 / Hematology / Radiation science … More / General surgery / Immunology / 生物物性学 / Pediatrics / Orthopaedic surgery / General pharmacology / Biological Sciences / Functional biochemistry / Cerebral neurosurgery / Ophthalmology Less
Keywords	Principal Investigator CD2 / LFA / VLA / FasL / アポトーシス / パーフォリン / NK / MHC / TWEAK / HIV … More / Lyn / CD86 / CD80 / tolerance / 自己免疫疾患 / コラーゲン誘発性関節炎 / TNF / CD48 / CD28 / Fas / CD8 / CD4 / 炎症 / Fn14 / Src / SSl-1 / STAT / cytokine / サイトカイン / CD95L / TNF-R / CD40 / signal transduction / HSI / 遺伝子 / monoclonal antibody / 拒絶反応 / 免疫寛容 / 移植拒絶 / トランスフェクタント / TcR / lymphocyte / mAb / 自己免疫 / GVHD / T細胞レセプター / IgE / B細胞 / アレルギー / B70 / LAK / パ-フォリン / ILー2レセプター / レトロウイルス / FcεRI / FCER2 / FCER1A / 一塩基置換多型 / アレルギー学 / 移植免疫 / 制御性T細胞 / 肝移植 / アレルギー・ぜんそく / アレルギー疾患 / 免疫学 / Monoclonal Antibody / Ts / T細胞機能分子 / サプレッサーT細胞 / DNAクローニング / FACS / リンパ球機能分子 / CD2遺伝子 / CD8遺伝子 / トランスフェクション / モノクローナル抗体 / TS / TNF-TNFR family / CD28-B7 family / costimulatory molecules / experimental autoimmune encephalomyelitis / murine model of asthma / experimental autoimmune uveoretinitis / collagen-induced arthritis / autoimmune diseases / B7RP-1 / TNF-TNFRファミリー / CD28-B7ファミリー / 補助シグナル分子 / 実験的自己免疫性脳脊髄炎 / OVA誘発性喘息 / 実験的自己免疫性ぶどう膜網膜炎 / 関節炎モデル / tumor rejection / angiogenesis / apoptosis / tumor / RANTES / GM-CSF / IL-8 / IκBα / 腫瘍拒絶 / 血管新生 / 腫瘍 / TGF-beta / CD40-CD40L / TCR-peptides / Smad / TGF-β / TCR / IL-6 / CD80, CD86 / CD40, CD40L / シグナル伝達 / anergy / エイズ / アナジー / CTLA-4 / Th2 / Th1 / 寛容 / CD27 / CD80,CD86 / ジーンターゲッティン / transplantation / B cell / autoantibody / gene / I-E / IL-5 / NZB / DR / 抗原ペプチド / SLE / ADF / IL-5リセプター / 同種心移植 / 自己抗体 / シグナル伝達機構 / auto immune disease / allograft rejection / ヘルパーT細胞 / Thy-1 / T cell / モノクロナール抗体 / 移植 / トレランス / lympocyte / 自然免疫 / HTLV-1 / 自己認識 / 免疫機能分子 / リンフォカイン / バイオテクノロジー / TATA / Oncgene / MRL / 免疫グロブリン遺伝子 / T細胞レセプター遺伝子 / クローナリティー / 分化抗原 / ホーミング / リンパ球の分化 / リンパ腫 / AKR白血病 / SJLリンパ腫 / クロノタイプ / 抗炎症作用 / TIM-4 / アレルギー・喘息 / アレルギー･喘息 / 喘息 / 抗体療法 / 関節リウマチ / クロスプレゼンテーション / 貪食 / 樹状細胞 / Tim-3 / CD63 / 脱顆粒 / ノックアウトマウス / Liht chain(LC)3 / インターフェロン / オートファジー / Th17細胞 / Th2細胞 / Th1細胞 / T細胞 / TIM-2 / T cell immunoglobulin and mucin domain (TIM)ファミリー / マスト細胞 / TIMファミリー / 細胞傷害活性 / IFN / CTL / 抗腫瘍効果 / 生体防御 / Fasリガンド / TRAIL / 細胞障害性リンパ球 / SIV感染カニクイサル / マトリックスメタロプロテアーゼ / AIDS / キラー細胞 / B7 / 細胞障害機序 / キラーT細胞 / Killer T / ECM / 8 T cell / r / Perforin / NK細胞 / IL-2R / HVG … More Except Principal Investigator Fas / IL-4 / IgE / FasL / GVHD / 免疫寛容 / HVGD / TNF-α / アポトーシス / GVL / metalloproteinase inhibitor / GVH / HVG / MPI / CD2 / 自己免疫疾患 / サイトカイン / メタロプロテナーゼインヒビター / TNF-alpha / 接着分子 / RA / インテグリン / T cell receptor / TNF / シグナル伝達 / T細胞抗原レセプター / キラーT細胞 / IL-12 / 免疫病 / NK細胞 / ILー2 / CCR4 / CCR5 / chemokine / TNF family / Th2 / Th1 / SLE / B cell / T cell / B細胞 / T細胞 / インターロイキン4 / 副作用 / VLA-5 / VLA-4 / 活性化 / フィブロネクチン / apoptosis / self-tolerance / B70 / Biosensor / NMR / 転写因子 / M.T.T / IL-2 / ICAM-1 / LFA-1 / CD48 / CD8 / CD4 / IL-6 / IL-5 / 遺伝子治療 / トレランス / 免疫制御 / T細胞活性化 / T細胞分化 / 胸腺 / HLA / 分子遺伝学 / Treg / 妊娠 / 酪酸 / GPR41 / Aire / 制御性T細胞 / 短鎖脂肪酸 / 食物繊維 / 腸内細菌 / 移植免疫 / 細胞治療 / 移植外科学 / 移植・再生医療 / Monoclonal antibody / Adhesion molecule / Activation / Differentiation / NK cell / B細胞の分化 / T細胞の分化 / リンパ球機能 / トランスフェクタント / モノクローナル抗体 / cDNA / マウス / 単クロ-ン抗体 / 分化 / Nuclear Magnetic Resonance / T-Cell Receptor / Immunoglobulin / 細胞間相互作用 / ストップト・フロー法 / X線結晶解析 / タンパク質の高次構造 / 免疫学 / Apoptosis / Fas ligand / ケモカイン受容体 / co-stimulatory分子 / 関節リウマチ / gene therapy / bone marrow transplantation / gld mice / autoimmunity / 骨髄移植 / gldマウス / 自己免疫 / Transcriptional factor / Crystallin gene / Polycomb genes / Transgenics / Immunological tolerance / 有機リン系農薬センサー / 水晶体特異的遺伝子発現 / ポリコ-ム遺伝子 / 発生工学 / super antigen / Kawasaki disease / HHV-6 / Heat shock protein / Vβレパトア / スーパー抗原 / 川崎病 / Interleukin-4 / Adversed Reaction / Iodimated Contrast Media / 水溶性ヨード造影剤 / extracellular matrix / chondrocyte / integrin / 接着因子 / マトリックスメタロプロテアーゼ / 分子生物学 / 機械的ストレス / 細胞外マトリックス / 軟骨細胞 / IgE allotype / アロタイプ / sIL-4R / sIL-1R / IgG1 / 可溶性IL-1リセプター / 可溶性IL-4リセプター / IL-4レセプター / IL-1レセプター / IL-4リセプター / IL-1リセプター / Interleukin 4 / contrast media / Adverse reaction / Iodinated contrast media / 抗原抗体反応 / 造影剤 / ヨード造影剤 / gene knockout mouse / transgenic mouse / international symposium / information exchanges / providing information / group of generalization / immune tolerance / immune regulation / 免疫応答 / ジーンノックアウトマウス / トランスジェニックマウス / 国際シンポジウム / 情報交換 / 情報提供 / 総括班 / rat mast cells / fibronectin receptor / fibronectin / 抗VLA-4抗体 / RGDペプチド / VLA-3,4,5 / コラーゲン(CL) / ラミニン(LM) / ビトロネクチン(VN) / フィブロネクチン(FN) / ECM / FcεRI / マスト細胞 / antigenic peptide / MHC molecule / adhesion molecule / CD5^+B cells / autoimmune disease / 抗原ペプチド / MHC分子 / CD5^+B細胞 / アポプトーシス / 自己トレランス / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / major histocompatibility antigen / autoimmune diseases / gene expression / transcription factor / signal transduction / receptor / cytokine / lymphocytes / 主要組織適合抗原 / 遺伝子発現 / レセプター / リンパ球 / Immunotherapy / Gold therapy / IgE supprossion / ILー4 / MTT / 免疫療法 / 慢性関節リウマチ / 金製剤 / IgE産生抑制 / Autoimmune disease / Superantigen / Antigen processing / RAG 1 / Cytokine receptor / ス-パ-抗原 / 抗体のプロセッシング / RAG1 / サイトカインレセプタ- / Cancer Metastasis / DNA Repair / Signal Transduction / Tumor Suppressor Genes / Oncogenes / German-Japanese Collaborative Program in Cancer Research / French-Japanese Collaborative Program in Cancer Research / International Exchange Program / がん抑制遣伝子 / がん遣伝子 / 2国間共同研究 / ヒトゲノム / DNA修復 / がん転移 / がん細胞 / がん抑制遺伝子 / がん遺伝子 / integrins / tolerance / T cell activation / extracellular matrix receptor / adhesion molecules / CD54 / 18 / CD11a / CD_2 / ICAMー1 / LFAー1 / 細胞外マトリクス受容体 / 細胞間接着分子 / Acute phase reaction / NF-IL-6 / Interleukin / Recombinase / IgM receptor / Major histocompatibility complex (MHC) / The US-Japan Immunology Symposium / 急性期反応 / MF-IL-6 / インタ-ロイキン / リコンビナ-ゼ / IgMレセプタ- / 主要組織適合抗原(MHC) / Tリンパ球レセプタ- / 日米免疫シンポジウム / Poreforming Protein / ヒト脳腫瘍の治療 / CD16 / CD3 / Lybhokine-activatedkiller / 組みかえDNA / インターロイキン / トランスゲニックマウス / サブトラクション / cDNAクローニング / ハプテン / 抑制性T細胞 / 臓器移植 / 移植免疫寛容 / 腎臓移植 / TRAILレセプター / PSC / Importin β1 / 胆管閉塞 / がん抗体療法 / 局在 / 腫瘍細胞 / DR5 / TRAIL / 抗腫瘍免疫 / 抗アポトーシス遺伝子 / ノックアウトマウス / マイクロアレイ / NF-κB / Btk / 自己抗原 / ケモカイン / 自己免疫症患 / 免疫不全症 / 免疫病の修復 / 粘膜免疫 / チロシンキナーゼ / 免疫寛容の破綻 / 原発性免疫不全症 / 慢性炎症 / レトロウイルス疾患 / 情報伝達 / 発癌 / 細胞死 / 酸化ストレス / チオレドキシン / ADF / レドックス / 腫瘍浸潤リンパ球 / 悪性グリオーマ / アポートシス / ICE / グランザイム / 細胞障害機序 / 好中球 / Fasリガンド / パ-フォリン / 細胞傷害機序 / ペプチドモチーフ / クラスIMHC / T細胞レパトア / TIL / がん抗原 / 補助シグナル / T細胞エピトープ / MHCペプチド / 養子免疫療法 / NKT細胞 / ドレランス / がん免疫 / レクチン / リガンド分子 / NKレセプター / LAK細胞 / キラー細胞 / ILー2R / 10D1 / ヒトT細胞抗原 / HLAーDNAタイピング / 細胞障害性T細胞 / メラノサイト特異的自己免疫疾患 / EBウイルス / PCR / 免疫抑制剤 / メラノサイト / 細胞接着因子 / 実験的自己免疫網膜ぶどう / HLAクラスII遺伝子 / 免疫抑制治療 / 疫学 / メラノサイト特異的自己免疫症患 / 交感性眼炎 / 原田病 / 二反応性抗体 / パーフォリン / MHC非拘束性認識 / 細胞障害性 / ILー2受容体 / NK / LAK Less

Multidimensional Analysis of operationally tolerance in living donor liver transplant patientsPrincipal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Juntendo University
Maternal high fiber diet during pregnancy and lactation influences regulatory T cell differentiation in offspring in mice
- Principal Investigator
  
  NAKAJIMA Akihito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
体外誘導免疫制御性リンパ球を用いた細胞治療による免疫寛容誘導に関する研究
- Principal Investigator
  
  山下健一郎
- Project Period (FY)
  2014 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General surgery
- Research Institution
  Hokkaido University
Immune regulation on autoimmune and allergic diseases by the TIM family moleculesPrincipal Investigator
- Principal Investigator
  
  Okumura Ko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Juntendo University
Immunotolerance induction in kidney transplantation by infusion of regulatory cells
- Principal Investigator
  
  Koyama Ichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Women's Medical University
Development of the antibody medical treatment to autoimmune and asthmatic diseases based on new target molecule.Principal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
Development of strategy to treat allergic diseases via targeting surface molecules on lymphocytes and intracellular signaling moleculesPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
Contribution of intracellular TRAIL receptor to regulation of apoptosis induced by TRAIL
- Principal Investigator
  
  KOJIMA Yuko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Juntendo University
Statistical analyses of allergy-related polymorphismsPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Functional analysis of costimulatory molecules for autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Juntendo University
REGULATION OF TUMOR VESSEL FORMATION BY THE IMMUNE SYSTEMPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  JUNTENDO UNIVERSITY
TNFにより誘導される遺伝子群の同定とその治療への応用
- Principal Investigator
  
  NAKANO Hiroyasu
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Differential effects of anti Fas ligand and MPI on GVHD pathologies
- Principal Investigator
  
  HIRANO Takao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
Differential effects of anti Fas ligand and anti TNF-alpha antibodies on GVHD pathologies
- Principal Investigator
  
  HIRANO takao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Juntendo University
免疫病とその修復
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
細胞障害性リンパ球による標的細胞破壊機構の解明およびその制御Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving graft-versus-leukemia effect of allogeneic bone marrow transplantation
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  JUNTENDO UNIVERSITY
がん免疫寛容のメカニズムとその制御
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Chiba University
細胞死(アポトーシス)誘導分子をターゲットとしたAIDS発症抑制Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Immune regulation and signal tranductionPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  Juntendo University School of Medicine
Role of Fas/FasL interaction in self-tolerance : evaluated by bone marrow transplantation
- Principal Investigator
  
  KOBATA Tetsuji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Molecular Mechanism of Autoimmunity and its regulation
- Principal Investigator
  
  NAKAJIMA Atsuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Nippon Medical School
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University, School of Medicine
Immune regulation and signal tranductionPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Juntendo University School of Medicine
レドックスによる情報伝達と病態制御に関する総合的研究
- Principal Investigator
  
  YODOI Junji
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyoto University
Study on Etiology and Pathogenesis of Kawasaki Disease
- Principal Investigator
  
  KATO Hirohisa
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pediatrics
- Research Institution
  Kurume University
Studies on the differention and activation mechanisms of T cell vi lymphocye functioning antigen (LFA).Principal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University School of Medicine
抗潰瘍エフェクター機序の解析
- Principal Investigator
  
  八木田秀雄
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
悪性グリオーマ浸潤リンパ球に於けるT細胞抗原レセプターの分子生物学的解析
- Principal Investigator
  
  新田泰三
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Juntendo University
In vivo effects of sIL-IR and sIL-4R on IgE production and regulation of allergic reaction
- Principal Investigator
  
  MIYAJIMA Hiroaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Juntendo University School of Medicine
Regulation of immunities induce by GVHD, HVGD with cytokine abnormalities
- Principal Investigator
  
  HIRANO Takao
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Juntendo University School of Medicine
A study on response to mechanical stress in human chondrocytes
- Principal Investigator
  
  YAMAUCHI Yasuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Juntendo University School of Medicine, Deparyment of Orthopedic surgery
Immunological Aspect for Adversed Reaction of Contrast Media
- Principal Investigator
  
  MIYAUCHI Teruyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University School of Medicine
Regulation of Gene Expression
- Principal Investigator
  
  TANIGUCHI Masaru
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Chiba University
Studies on molecular mechanisms of autoimmune diseases
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
Analysis of adhesion molecules on mast cellsPrincipal Investigator
- Principal Investigator
  
  HIRANO Takao, 奥村康
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Juntendo University
Molecular mechanism of immune regulation and immune tolerance
- Principal Investigator
  
  SASAZUKI Takehiko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Molecular mechanisms of immune diseases.Principal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Immunological Investigation on the adverse reaction of iodinated contrast media
- Principal Investigator
  
  KATAYAMA Hitoshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  Juntendo University School of Medicine
研究課的ヒトキラー細胞に発現する新しいレクチン様分子の構造と腫瘍障害性における機能の解析
- Principal Investigator
  
  屋部登志雄
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
キラーT細胞による腫瘍細胞の認識と破壊機構の解明Principal Investigator
- Principal Investigator
  
  八木田秀雄, 奥村康
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
免疫制御・寛容の分子機構
- Principal Investigator
  
  SASAZUKI Takehiko
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Institution
  Kyushu University
Studies on the regulation of gene expression in lymphoid cells.
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
Sudies on the differention and activation mechanisms of T cell via lymphocye functioning antigen (LFA).Principal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of Tokyo
Studies on the regulation of gene expression in lymphoid cells.
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Osaka University
サイトカインによるIgE抑御機構にもとずくI型アレルギー疾患治療への試み
- Principal Investigator
  
  HIRANO Takao
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Juntendo University School of Medicine
キラ-T細胞による腫瘍細胞の認識と破壊機構の解明Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
原田病の発症機構に関する研究
- Principal Investigator
  
  大野重昭
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Yokohama City University
ヒトT細胞膜抗原10D1の胸線内T細胞分化・活性化における役割の解析
- Principal Investigator
  
  OBATA Tetsuji
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
キラ-T細胞による腫瘍細胞の認識と破壊機構の解明Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Molecular biological study on intercellular adhesion molecules involved in activation and differentiation of hematopoietic cells.
- Principal Investigator
  
  YAGITA Hideo
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University School of Medicine
宿主側からみた腫瘍増殖機序の分子免疫学的解析Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
キラー細胞による腫瘍細胞障害性とその誘導機序及びそれに対する抵抗性の分子的解析
- Principal Investigator
  
  YAGITA Hideo
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
HIV感染によるCD4陽性T細胞減少機序の分子免疫学的解析Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Juntendo University
Exchange of the informations in the cooperative immunology research between the US-Japan Bords.
- Principal Investigator
  
  KISHIMOTO Tadamitsu
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Institute for Molecular and Cellular Biology, Osaka University
Immuno-Melecular characterization of lymphocyte functioning antigen (LFA)Principal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University School of Medicine
MHC非抱亜性キラー細胞による腫瘍の認識及び破壊機構の解明とその制癌への応用
- Principal Investigator
  
  八木田秀雄
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
Importance of CD2-LFA-3 interaction in differentiation and function of T and NK cells.
- Principal Investigator
  
  YAGITA Hideo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University School of Medicine
宿主側から見た腫瘍増殖機序の分子免疫学的解析Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
生命科学技術の進展への象疫学の対応Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
マウス及びヒトT細胞白血病の転移におけるT細胞クロノタイプ及び分化抗原の転換Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
生命科学技術の進展への免疫学の対応
- Principal Investigator
  
  多田富雄
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
宿主側から見た腫瘍増殖機序の分子免疫学的解析Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
Immuno Molecular Analysis of Suppressor T cell receptorPrincipal Investigator
- Principal Investigator
  
  OKUMURA Ko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
T細胞系腫瘍のクロノタイプ発現様式の解明と抗クロノタイプ抗体の制癌への応用Principal Investigator
- Principal Investigator
  
  奥村康
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Juntendo University
抑制性T細胞抗源レセプター遺伝子の単離・構造解析と機能
- Principal Investigator
  
  KUMAGAI Yoshihiro
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Juntendo University
Structure and Functions of Proteins of Immunological Interest
- Principal Investigator
  
  ARATA Yoji
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  The University of Tokyo

[Journal Article] Maternal High Fiber Diet during Pregnancy and Lactation Influences Regulatory T Cell Differentiation in Offspring in Mice2017
- Author(s)
  Nakajima, A. Kaga, N. Nakanishi, Y. Ohno, H. Miyamoto, J. Kimura, I. Hori, S. Sasaki, T. Hiramatsu, K. Okumura, K. Miyake, S. Habu, S. Watanabe, S.
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 10 Pages: 3516-3524
- DOI
  10.4049/jimmunol.1700248
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-17H04218, KAKENHI-PROJECT-15H05344, KAKENHI-PROJECT-15K08533
[Journal Article] Subcutaneous Allergic Sensitization to Protease Allergen Is Dependent on Mast Cells but Not IL-33: Distinct Mechanisms between Subcutaneous and Intranasal Routes2016
- Author(s)
  Kamijo S, Suzuki M, Hara M, Shimura S, Ochi H, Maruyama N, Matsuda A, Saito H, Nakae S, Suto H, Ichikawa S, Ikeda S, Ogawa H, Okumura K, Takai T.
- Journal Title
  
  J Immunol
  
  Volume: 196 Issue: 9 Pages: 3559-3569
- DOI
  10.4049/jimmunol.1500717
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860759, KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26462698
[Journal Article] Innate basophil IL-4 responses against allergens, endotoxin, and cytokines require the Fc receptor γ-chain.2016
- Author(s)
  Kamijo S, Nunomura S, Ra C, Kanaguchi Y, Suzuki Y, Ogawa H, Okumura K, Takai T.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 137 Issue: 5 Pages: 1613-1615
- DOI
  10.1016/j.jaci.2015.10.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26860759
[Journal Article] An antimicrobial peptide with angiogenic properties, AG-30/5C, activates human mast cells through the MAPK and NF-κB pathways.2016
- Author(s)
  Kanazawa K, Okumura K, Ogawa H, Niyonsaba F.
- Journal Title
  
  Immunol Res
  
  Volume: 64 Issue: 2 Pages: 594-603
- DOI
  10.1007/s12026-015-8759-5
- NAID
  130007632014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26461703
[Journal Article] Release from Th1-type immune tolerance in spleen and enhanced production of IL-5 in Peyer's patch by cholera toxin B induce the glomerular deposition of IgA.2016
- Author(s)
  Yamanaka T, Tamauchi H, Suzuki Y, Suzuki H, Horikoshi S, Terashima M, Iwabuchi K, Habu S, Okumura K, Tomino Y.
- Journal Title
  
  Immunobiol
  
  Volume: 221 Issue: 4 Pages: 577-585
- DOI
  10.1016/j.imbio.2015.12.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460502, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-15K09274
[Journal Article] Role of PU.1 in MHC class II Expression via CIITA Transcription in Plasmacytoid Dendritic Cells2016
- Author(s)
  Miura R, Kasakura K, Nakano N, Hara M, Maeda K, Okumura K, Ogawa H, Yashiro T, Nishiyama C
- Journal Title
  
  PLOS ONE
  
  Volume: 11 Issue: 4 Pages: e0154094-e0154094
- DOI
  10.1371/journal.pone.0154094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18702, KAKENHI-PROJECT-16J03241, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-16K15092
[Journal Article] Angiogenic peptide (AG)-30/5C activates human keratinocytes to produce cytokines/chemokines and to migrate and proliferate via MrgX receptors.2016
- Author(s)
  Kiatsurayanon C, Niyonsaba F, Chieosilapatham P, Okumura K, Ikeda S, Ogawa H.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 83 Issue: 3 Pages: 190-9
- DOI
  10.1016/j.jdermsci.2016.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26461703
[Journal Article] Epicutaneous allergic sensitization by cooperation between allergn protease activity and mechanical skin barrier damage in mice2016
- Author(s)
  Shimura S, Takai T, Iida H, Maruyama N, Ochi H, Kamijo S, Nishioka I, Hara M, Matsuda A, Saito H, Nakae S, Ogawa H, Okumura K, Ikeda S.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Issue: 7 Pages: 1408-1417
- DOI
  10.1016/j.jid.2016.02.810
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26462698, KAKENHI-PROJECT-26860759
[Journal Article] Presensitization to Ascaris antigens promotes induction of mite-speciﬁc IgE upon mite antigen inhalation in mice2016
- Author(s)
  Suzuki M, Hara M, Ichikawa S, Kamijo S, Nakazawa T, Hatanaka H, Akiyama K, Ogawa H, Okumura K, Takai T
- Journal Title
  
  Allergol. Int.
  
  Volume: 65 Issue: 1 Pages: 44-51
- DOI
  10.1016/j.alit.2015.07.003
- NAID
  130005290333
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26860759, KAKENHI-PROJECT-26293087
[Journal Article] A pilot study of operational tolerance with a regulatory T cell-based cell therapy in living donor liver transplantation.2016
- Author(s)
  ①Todo S, Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Habu S, Demetris AJ, Okumura K
- Journal Title
  
  Hepatology
  
  Volume: 00 Issue: 2 Pages: 00-00
- DOI
  10.1002/hep.28459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461964, KAKENHI-PROJECT-26253068, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-16K08683, KAKENHI-PROJECT-26670572, KAKENHI-PROJECT-16H05398
[Journal Article] Critical Role of Transcription Factor PU.1 in the Function of the OX40L/TNFSF4 Promoter in Dendritic Cells.2016
- Author(s)
  Yashiro T, Hara M, Ogawa H, Okumura K, Nishiyama C.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 34825-34825
- DOI
  10.1038/srep34825
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-16K15092
[Journal Article] CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway.2015
- Author(s)
  Hatano R, Ohnuma K, Otsuka H, Komiya E, Taki I, Iwata S, Dang NH, Okumura K, Morimoto C.
- Journal Title
  
  J Immunol.
  
  Volume: Vol 194 Issue: 3 Pages: 960-72
- DOI
  10.4049/jimmunol.1402143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J12067, KAKENHI-PROJECT-24591442, KAKENHI-PROJECT-26670486, KAKENHI-PROJECT-26830114, KAKENHI-PROJECT-26860760, KAKENHI-PROJECT-15K15324, KAKENHI-PROJECT-15H04879, KAKENHI-PROJECT-26293087
[Journal Article] Cysteine protease antigens cleave CD123, the α subunit of murine IL-3 receptor, on basophils and suppress IL-3-mediated basophil expansion2015
- Author(s)
  Nishikado H, Fujimura T, Taka H, Mineki R, Ogawa H, Okumura K, Takai T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 印刷中 Issue: 2 Pages: 261-266
- DOI
  10.1016/j.bbrc.2015.03.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-15K00569, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26293087
[Journal Article] Human β-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes2015
- Author(s)
  Smithrithee R, Niyonsaba F, Kiatsurayanon C, Ushio H, Ikeda S, Okumura K, Ogawa H
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 77(1) Issue: 1 Pages: 46-53
- DOI
  10.1016/j.jdermsci.2014.12.001
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461703, KAKENHI-PROJECT-26293087
[Journal Article] Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis.2015
- Author(s)
  Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, Murayama K.
- Journal Title
  
  Sci Rep.
  
  Volume: 8;5 Issue: 1 Pages: 13737-13751
- DOI
  10.1038/srep13737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K00569, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-25430140, KAKENHI-PROJECT-26293087
[Journal Article] Notch signaling enhances FceRI-mediated cytokine production by mast cells through direct and indirect mechanisms2015
- Author(s)
  Nakano, N., Nishiyama, C., Yagita, H., Hara, M., Motomura, Y., Kubo, M., Okumura, K., and Ogawa, H
- Journal Title
  
  J. Immunol
  
  Volume: 194(9) Issue: 9 Pages: 4535-44
- DOI
  10.4049/jimmunol.1301850
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24249058, KAKENHI-PROJECT-24591667, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-15K15158, KAKENHI-PUBLICLY-15H01162, KAKENHI-PUBLICLY-15H01267, KAKENHI-PROJECT-26293087
[Journal Article] Involvement of PU.1 in NFATc1 promoter function in osteoclast development2015
- Author(s)
  Ishiyama K, Yashiro T, Nakano N, Kasakura K, Miura R, Hara M, Kawai F, Maeda K, Tamura N, Okumura K, Ogawa H, Takasaki Y, Nishiyama C
- Journal Title
  
  Allergol. Int.
  
  Volume: 64 Issue: 3 Pages: 241-247
- DOI
  10.1016/j.alit.2015.01.006
- NAID
  130005290298
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-15K18702, KAKENHI-PROJECT-26293087
[Journal Article] An Interleukin-33-Mast Cell-Interleukin-2 Axis Suppresses Papain-Induced Allergic Inflammation by Promoting Regulatory T Cell Numbers.2015
- Author(s)
  Morita H, Arae K, Unno H, Miyauchi K, Toyama S, Nambu A, Oboki K, Ohno T, Motomura K, Matsuda A, Yamaguchi S, Narushima S, Kajiwara N, Iikura M, Suto H, McKenzie AN, Takahashi T, Karasuyama H, Okumura K, Azuma M, Moro K, Akdis CA, Galli SJ, Koyasu S, Kubo M, Sudo K, Saito H, Matsumoto K, Nakae S.
- Journal Title
  
  Immunity
  
  Volume: 43 Issue: 1 Pages: 175-86
- DOI
  10.1016/j.immuni.2015.06.021
- NAID
  40020962854
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09560, KAKENHI-PROJECT-26461491, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-26462834, KAKENHI-PUBLICLY-15H01162, KAKENHI-PUBLICLY-15H01166, KAKENHI-PUBLICLY-15H01267, KAKENHI-PROJECT-15H05786, KAKENHI-PROJECT-15H02515, KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15377, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26293110
[Journal Article] PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells2015
- Author(s)
  Yashiro T, Kubo M, Ogawa H, Okumura K, Nishiyama C
- Journal Title
  
  PLoS One
  
  Volume: 10(9) Issue: 9 Pages: e0137699-e0137699
- DOI
  10.1371/journal.pone.0137699
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01162, KAKENHI-PUBLICLY-15H01267, KAKENHI-PROJECT-26293087
[Journal Article] The Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells.2015
- Author(s)
  Yamazaki S, Nakano N, Honjo A, Hara M, Maeda K, Nishiyama C, Kitaura J, Ohtsuka Y, Okumura K, Ogawa H, Shimizu T
- Journal Title
  
  Journal of immunology
  
  Volume: 195(7) Issue: 7 Pages: 3427-3435
- DOI
  10.4049/jimmunol.1402856
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-26461494, KAKENHI-PROJECT-26461643, KAKENHI-PROJECT-15K15376, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26293231
[Journal Article] Roles of retinoic acid-inducible gene-I-like receptors (RLRs), Toll-like receptor (TLR) 3 and 2'-5' oligoadenylate synthetase as viral recognition receptors on human mast cells in response to viral infection.2015
- Author(s)
  Tsutsui-Takeuchi M, Ushio H, Fukuda M, Yamada T, Niyonsaba F, Okumura K, Ogawa H, Ikeda S.
- Journal Title
  
  Immunol Res
  
  Volume: 61 Issue: 3 Pages: 240-9
- DOI
  10.1007/s12026-014-8617-x
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591470, KAKENHI-PROJECT-26293087
[Journal Article] IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice.2015
- Author(s)
  Morita H, Arae K, Unno H, Toyama S, Motomura K, Matsuda A, Suto H, Okumura K, Sudo K, Takahashi T, Saito H, Matsumoto K, Nakae S.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 7 Pages: e0134226-e0134226
- DOI
  10.1371/journal.pone.0134226
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461491, KAKENHI-PROJECT-15H04866, KAKENHI-PROJECT-15K15377, KAKENHI-PROJECT-26293087
[Journal Article] Characteristics of alveolar macrophages from murine models of OVA-induced allergic airway inflammation and LPS-induced acute airway inflammation2015
- Author(s)
  1)Katsura Y, Harada N, Harada S, Ishimori A, Makino F, Ito J, Kamachi F, Okumura K, Akiba H, Atsuta R, Takahashi K
- Journal Title
  
  Experimental Lung Research
  
  Volume: 41 Issue: 7 Pages: 370-382
- DOI
  10.3109/01902148.2015.1044137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19031, KAKENHI-PROJECT-25461167, KAKENHI-PROJECT-25461503, KAKENHI-PROJECT-26293087
[Journal Article] Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice.2015
- Author(s)
  Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, Shibata S, Shimada S, Nakao A
- Journal Title
  
  J Invest Dermatol
  
  Volume: 135 Issue: 12 Pages: 3001-3008
- DOI
  10.1038/jid.2015.316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19573, KAKENHI-PROJECT-26220201, KAKENHI-PROJECT-15H04864, KAKENHI-PROJECT-26461684, KAKENHI-PROJECT-26670475, KAKENHI-PROJECT-26860874, KAKENHI-PROJECT-26293087
[Journal Article] Circadian regulation of allergic reactions by the mast cell clock in mice.2014
- Author(s)
  Nakamura Y, Nakano N, Ishimaru K, Hara M, Ikegami T, Tahara Y, Katoh R, Ogawa H, Okumura K, Shibata S, Nishiyama C, Nakao A
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 133(2) Issue: 2 Pages: 568-575
- DOI
  10.1016/j.jaci.2013.07.040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591667, KAKENHI-PROJECT-25893265, KAKENHI-PROJECT-26293087
[Journal Article] The human cathelicidin LL-37 host defense peptide upregulates tight junction-related proteins and increases human epidermal keratinocyte barrier function.2014
- Author(s)
  Akiyama T, Niyonsaba F, Kiatsurayanon C, Nguyen TT, Ushio H, Fujimura T, Ueno T, Okumura K, Ogawa H, Ikeda S
- Journal Title
  
  J Innate Immun
  
  Volume: 6 Issue: 6 Pages: 739-53
- DOI
  10.1159/000362789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26430145, KAKENHI-PROJECT-26461703
[Journal Article] Commensal Bacteria Regulate Thymic Aire Expression2014
- Author(s)
  Nakajima A, Negishi N, Tsurui H, Kadowaki-Ohtsuji N, Maeda K, Nanno M, Yamaguchi Y, Shimizu N, Yagita H, Okumura K, Habu S.
- Journal Title
  
  PloS One
  
  Volume: 9 Issue: 8 Pages: e105904-e105904
- DOI
  10.1371/journal.pone.0105904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25330349, KAKENHI-PROJECT-25860818, KAKENHI-PROJECT-26293087
[Journal Article] Host Defense (Antimicrobial) Peptide, Human β-Defensin-3, Improves the Function of the Epithelial Tight-Junction Barrier in Human Keratinocytes.2014
- Author(s)
  Kiatsurayanon C, Niyonsaba F, Smithrithee R, Akiyama T, Ushio H, Hara M, Okumura K, Ikeda S, Ogawa H.
- Journal Title
  
  J invest Deramatol
  
  Volume: 143 Issue: 8 Pages: 2163-73
- DOI
  10.1038/jid.2014.143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591470, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26461703
[Journal Article] OX40 ligand regulates splenic CD8- dendritic cell-induced Th2 responses in vivo.2014
- Author(s)
  Kamachi F, Harada N, Usui Y, Sakanishi T, Ishii N, Okumura K, Miyake S, Akiba H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 444 Issue: 2 Pages: 235-240
- DOI
  10.1016/j.bbrc.2014.01.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10815, KAKENHI-PROJECT-23390261, KAKENHI-PROJECT-24390118, KAKENHI-PROJECT-24659487, KAKENHI-PROJECT-25461167, KAKENHI-PROJECT-25461503, KAKENHI-PROJECT-26293087
[Journal Article] Epicutaneous Administration of Papain Induces IgE and IgG Responses in a Cysteine Protease Activity-Dependent Manner2014
- Author(s)
  Iida H, Takai T, Hirasawa Y, Kamijo S, Shimura S, Ochi H, Nishioka I, Maruyama N, Ogawa H, Okumura K, Ikeda S
- Journal Title
  
  Allergol. Int.
  
  Volume: 63 Issue: 2 Pages: 219-226
- DOI
  10.2332/allergolint.13-OA-0621
- NAID
  130004477213
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26860759
[Journal Article] Potential role of myeloid cell/eosinophil-derived IL-17 in LPS-induced endotoxin shock.2014
- Author(s)
  Shimura E, Shibui A, Narushima S, Nambu A, Yamaguchi S, Akitsu A, Leonard WJ, Iwakura Y, Matsumoto K, Suto H, Okumura K, Sudo K, Nakae S
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 453 Issue: 1 Pages: 1-6
- DOI
  10.1016/j.bbrc.2014.09.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26860761
[Journal Article] Expressions of tight junction proteins Occludin and Claudin-1 are under the circadian control in the mouse large intestine: implications in intestinal permeability and susceptibility to colitis2014
- Author(s)
  Kyoko OO, Kono H, Ishimaru K, Miyake K, Kubota T, Ogawa H, Okumura K, Shibata S, Nakao A
- Journal Title
  
  PLoS One
  
  Volume: 9(5) Issue: 5 Pages: e98016-e98016
- DOI
  10.1371/journal.pone.0098016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25860852, KAKENHI-PROJECT-26293087
[Journal Article] Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FceRI-mediated mast cell activation.2014
- Author(s)
  Izawa, K., Isobe, M., Matsukawa, T., Ito, S., Maehara, A., Takahashi, M., Yamanishi, Y., Kaitani, A., Oki, T., Okumura, K., *Kitamura, T., and *Kitaura, J.
- Journal Title
  
  J. Allergy. Clin. Immunol.
  
  Volume: 133 Issue: 1 Pages: 270-273
- DOI
  10.1016/j.jaci.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-25893050, KAKENHI-PROJECT-26293087
[Journal Article] Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A22014
- Author(s)
  Inage E, Kasakura K, Yashiro T, Suzuki R, Baba Y, Nakano N, Hara M, Tanabe A, Oboki K, Matsumoto K, Saito H, Niyonsaba F, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T, and Nishiyama C
- Journal Title
  
  Journal of Immunology
  
  Volume: 192 Issue: 8 Pages: 3936-46
- DOI
  10.4049/jimmunol.1302366
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J10792, KAKENHI-PROJECT-24591475, KAKENHI-PROJECT-24591667, KAKENHI-PROJECT-25860883, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26461643
[Journal Article] TSLP expression induced via Toll-like receptor pathways in human keratinocytes2014
- Author(s)
  Takai T, Chen X, Xie Y, Vu AT, Le TA, Kinoshita H, Kawasaki J, Kamijo S, Hara M, Ushio H, Baba T, Hiramatsu K, Ikeda S, Ogawa H, Okumura K
- Journal Title
  
  Methods Enzymol
  
  Volume: 535 Pages: 371-387
- DOI
  10.1016/b978-0-12-397925-4.00021-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461711, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26860759
[Journal Article] TIM-4 has dual function in the induction and effector phases of murine arthritis.2013
- Author(s)
  Abe Y, Kamachi F, Kawamoto T, Makino F, Ito J, Kojima Y, Moustapha Ael D, Usui Y, Yagita H, Takasaki Y, Okumura K, Akiba H.
- Journal Title
  
  J Immunol
  
  Volume: 191 Pages: 4562-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Transcriptional regulation of the mouse CD11c promoter by AP-1 complex with JunD and Fra2 in dendritic cells2013
- Author(s)
  Hara, M., H. Yokoyama, K. Fukuyama, N. Kitamura, N. Shimokawa, K. Maeda, S. Kanada, T. Ito, Y. Usui, H. Ogawa, K. Okumura, M. Nishiyama, and C. Nishiyama
- Journal Title
  
  Mol Immunol
  
  Volume: 53 Issue: 3 Pages: 295-301
- DOI
  10.1016/j.molimm.2012.08.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Critical contribution of oxidative stress to TNFα-induced necroptosis downstream of RIPK1 activation.2013
- Author(s)
  Shindo R, Kakehashi H, Okumura K, Kumagai Y, Nakano H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 436 Issue: 2 Pages: 212-6
- DOI
  10.1016/j.bbrc.2013.05.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24390100, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25670167
[Journal Article] Human antimicrobial peptide LL-37 modulates proinflammatory responses induced by cytokine milieus and double-stranded RNA in human keratinocytes2013
- Author(s)
  Xue Chen
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 433 Issue: 4 Pages: 532-537
- DOI
  10.1016/j.bbrc.2013.03.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591251, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23591655, KAKENHI-PROJECT-25461711
[Journal Article] TIM-4 has dual function in the induction and effector phases of murine arthritis2013
- Author(s)
  Abe Y, Kamachi F, Kawamoto T, Makino F, Ito J, Kojima Y, Moustapha Ael D, Usui Y, Yagita H, Takasaki Y, Okumura K, Akiba H
- Journal Title
  
  Journal of Immunology
  
  Volume: 191巻 Issue: 9 Pages: 4562-4572
- DOI
  10.4049/jimmunol.1203035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10815, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-25461503
[Journal Article] CD49b-dependent estabhshment of T helper cell memory.2013
- Author(s)
  Hanazawa, A., Hayashizaki, K.,Shinoda, K., Yagita, H., Okumura, K., Löhning, M., Hara, T., Tani-ichi, S., Ikuta, K., Eckes, B.,Radbruch, A., Tokoyoda, K, and Nakayama, T.
- Journal Title
  
  Immuno1. Cell Bio1
  
  Volume: 91 Issue: 8 Pages: 524-531
- DOI
  10.1038/icb.2013.36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J02883, KAKENHI-PROJECT-23390260, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24790468, KAKENHI-PROJECT-24790469, KAKENHI-PUBLICLY-25111504, KAKENHI-PROJECT-25460589, KAKENHI-PROJECT-25860352
[Journal Article] The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions.2013
- Author(s)
  Niyonsaba F, Madera L, Afacan N, Okumura K, Ogawa H, Hancock RE.
- Journal Title
  
  J Leukoc Biol
  
  Volume: 94 Issue: 1 Pages: 159-70
- DOI
  10.1189/jlb.1012497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23591655
[Journal Article] Altered expression and function of hepatic natural killer T cells in obese and diabetic KK-A(y) mice.2013
- Author(s)
  Yamagata H, Ikejima K, Takeda K, Aoyama T, Kon K, Okumura K, Watanabe S.
- Journal Title
  
  Hepatol Res
  
  Volume: 43 Pages: 276-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation2013
- Author(s)
  Seiji Kamijo
- Journal Title
  
  J Immunol
  
  Volume: 190 Issue: 9 Pages: 4489-4499
- DOI
  10.4049/jimmunol.1201212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591251, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-25461711
[Journal Article] Dietary resveratrol prevents the development of food allergy in mice2012
- Author(s)
  Okada, Y., K. Oh-oka, Y. Nakamura, K. Ishimaru, S. Matsuoka, K. Okumura, H. Ogawa, M. Hisamoto, T. Okuda, and A. Nakao
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 9 Pages: e44338-e44338
- DOI
  10.1371/journal.pone.0044338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23659499, KAKENHI-PROJECT-23790904
[Journal Article] Involvement of PU.1 in Mast Cell/Basophil-Specific Function of the Human <i>IL1RL1/ST2</i> Promoter2012
- Author(s)
  Baba, Y., K. Maeda, T. Yashiro, E. Inage, F. Niyonsaba, M. Hara, R. Suzuki, Y. Ohtsuka, T. Shimizu, H. Ogawa, K. Okumura, and C. Nishiyama
- Journal Title
  
  Allergol. Int.
  
  Volume: 61 Issue: 3 Pages: 461-467
- DOI
  10.2332/allergolint.12-OA-0424
- NAID
  130004477155
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Blockade of CD70-CD27 Interaction Inhibits Induction of Allergic Lung Inflammation in Mice2012
- Author(s)
  Makino F, Ito J, Abe Y, Harada N, Kamachi F, Yagita H, Takahashi K, Okumura K, Akiba H
- Journal Title
  
  American journal of respiratory cell and molecular biology
  
  Volume: 47 Issue: 3 Pages: 298-305
- DOI
  10.1165/rcmb.2011-0354oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23390260
[Journal Article] TIM-1 signaling in B cells regulates antibody production2012
- Author(s)
  Ma J, Usui Y, Takeda K, Harada N, Yagita H, Okumura K, Akiba H
- Journal Title
  
  iochem Biophys Res Commun
  
  Volume: 406 Issue: 2 Pages: 223-228
- DOI
  10.1016/j.bbrc.2011.02.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23390260
[Journal Article] Inhibitory receptor PIR-B is exploited by Staphylococcus aureus for virulence2012
- Author(s)
  Nakayama M, Kurokawa K, Nakamura K, Lee BL, Sekimizu K, Kubagawa H, Hiramatsu K, Yagita H, Okumura K, Takai T, Underhill DM, Aderem A, Ogasawara K.
- Journal Title
  
  J Immunol
  
  Volume: 189 Issue: 12 Pages: 5903-5911
- DOI
  10.4049/jimmunol.1201940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390370, KAKENHI-PROJECT-23249009, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23659291, KAKENHI-PROJECT-24249016, KAKENHI-PROJECT-24590158, KAKENHI-PROJECT-24659215
[Journal Article] Expression pattern changes and function of RANKL during mouse lymph node microarchitecture development2012
- Author(s)
  Sugiyama, et al.
- Journal Title
  
  International Immunology
  
  Volume: 24 Issue: 6 Pages: 369-378
- DOI
  10.1093/intimm/dxs002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591375, KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23390260
[Journal Article] The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide.2012
- Author(s)
  Izawa K, Yamanishi Y, Maehara A, Takahashi M, Isobe M, Ito S, Kaitani A, Matsukawa T, Matsuoka T, Nakahara F, Oki T, Kiyonari H, Abe T, 0kumura K, Kitamura T, Kitaura J.
- Journal Title
  
  Immunity
  
  Volume: 16;37(5) Issue: 5 Pages: 827-39
- DOI
  10.1016/j.immuni.2012.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07783, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23791074, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002
[Journal Article] Cyclooxygenase-2 inhibition restores ultraviolet B-induced downregulation of ATP2A2/SERCA2 in keratinocytes : possible therapeutic approach of cyclooxygenase-2 inhibition for treatment of Darier disease2012
- Author(s)
  Kamijo, M., C. Nishiyama, A. Takagi, N. Nakano, M. Hara, S. Ikeda, K. Okumura, and H. Ogawa
- Journal Title
  
  Br J Dermatol
  
  Volume: 166 Issue: 5 Pages: 1017-1022
- DOI
  10.1111/j.1365-2133.2011.10789.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24591667
[Journal Article] GATA2 is a critical transactivator for the human IL1RL1/ST2 promoter in mast cells/basophils : opposing roles for GATA2 and GATA1 in human IL1RL1/ST2 gene expression2012
- Author(s)
  Baba, Y., K. Maeda, T. Yashiro, E. Inage, K. Kasakura, R. Suzuki, F. Niyonsaba, M. Hara, A. Tanabe, H. Ogawa, K. Okumura, Y. Ohtsuka, T. Shimizu, and C. Nishiyama
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 39 Pages: 32689-32696
- DOI
  10.1074/jbc.m112.374876
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Expression and Functional Characterization of Retinoic Acid-Inducible Gene-I-Like Receptors of Mast Cells in Response to Viral Infection.2012
- Author(s)
  Fukuda M, Ushio H, Kawasaki J, Niyonsaba F, Takeuchi M, Baba T, Hiramatsu K, Okumura K, Ogawa H.
- Journal Title
  
  Journal of Innate Immunity
  
  Volume: 5 Issue: 2 Pages: 163-173
- DOI
  10.1159/000343895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590402, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24591470
[Journal Article] Critical role of transcription factor PU. 1 in the expression of CD80 and CD86 on dendritic cells2011
- Author(s)
  Kanada, S., C. Nishiyama, N. Nakano, R. Suzuki, K. Maeda, M. Hara, N. Kitamura, H. Ogawa, and K. Okumura
- Journal Title
  
  Blood
  
  Volume: 117 Issue: 7 Pages: 2211-2222
- DOI
  10.1182/blood-2010-06-291898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Anti-TIM-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells2011
- Author(s)
  Kawamoto T, Abe Y, Ito J, Makino F, Kojima Y, Usui Y, Ma J, Morimoto S, Yagita H, Okumura K, Takasaki Y, Akiba H
- Journal Title
  
  Arthritis Res Ther
  
  Volume: 13 Issue: 2
- DOI
  10.1186/ar3288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591098, KAKENHI-PROJECT-23390260
[Journal Article] Notch1-mediated signaling induces MHC class II expression through activation of class II transactivator promoter III in mast cells2011
- Author(s)
  Nakano, N., C. Nishiyama, H. Yagita, A. Koyanagi, H. Ogawa, and K. Okumura
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 14 Pages: 12042-12048
- DOI
  10.1074/jbc.m110.138966
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390260
[Journal Article] Okumura K., Kamradt T., Saito H., Nakae S. Paracrine IL-33 stimulation enhances lipopolysaccharide-mediated macrophage2011
- Author(s)
  Ohno T., Oboki K., Kajiwara N., Tanaka S., Ikeda M., Iikura M., Akiyama T., Inoue J., Matsumoto K., Sudo K., Azuma M.,
- Journal Title
  
  Plos One
  
  Volume: 6 Issue: 4 Pages: 18404-18404
- DOI
  10.1371/journal.pone.0018404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390148, KAKENHI-PUBLICLY-22021012, KAKENHI-PROJECT-22659094, KAKENHI-PROJECT-22790951, KAKENHI-PROJECT-22790952, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23390262, KAKENHI-PROJECT-23590475, KAKENHI-PROJECT-21390303
[Journal Article] Notch1-mediated signaling induces MHC class II expression through the activation of class II transactivator promoter III in mast cells.2011
- Author(s)
  Nakano N., C.Nishiyama, H.Yagita, A.Koyanagi, H.Ogawa, K.Okumura.
- Journal Title
  
  J Biol Chem. (in press)
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Critical role of transcription factor PU.1 in the expression of CD80 and CD86 on dendritic cells.2011
- Author(s)
  Kanada S., C.Nishiyama, N.Nakano, R.Suzuki, K.Maeda, M.Hara, N.Kitamura, H.Ogawa, K.Okumura.
- Journal Title
  
  Blood 117
  
  Pages: 2211-2222
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Tumor necrosis factor receptor-associated factor (TRAF)2 controls homeostasis of the colon to prevent spontaneous development of murine inflammatory bowel disease.2011
- Author(s)
  Piao J.H., M.Hasegawa, B.Heissig, K.Hattori, K.Takeda, Y.Iwakura, K.Okumura, N.Inohara, H.Nakano.
- Journal Title
  
  J Biol Chem (selected as "Papers of the Week" (in press)
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Crucial role for autophagy in degranulation of mast cells.2011
- Author(s)
  Ushio H., T.Ueno, Y.Kojima, M.Komatsu, S.Tanaka, A.Yamamoto, Y.Ichimura, J.Ezaki, K.Nishida, S.Komazawa-Sakon, F.Niyonsaba, T.Ishii, T.Yanagawa, E.Kominami, H.Ogawa, K.Okumura, H.Nakano.
- Journal Title
  
  J Allergy Clin Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Anti-T cell immunoglobulin and mucin domain-2 monoclonal antibody exacerbates collagen-induced arthritis by stimulating B cells.2011
- Author(s)
  Kawamoto T., Y.Abe, J.Ito, F.Makino, Y.Kojima, Y.Usui, J.Ma, S.Morimoto, H.Yagita, K.Okumura, Y.Takasaki, H.Akiba.
- Journal Title
  
  Arthritis Res Ther 13(in press)
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Extracellular double-stranded RNA induces TSLP via an endosomal acidification-and NF-κB-dependent pathway in human keratinocytes2011
- Author(s)
  Anh Tuan Vu, et al
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131 Issue: 11 Pages: 2205-2212
- DOI
  10.1038/jid.2011.185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591251, KAKENHI-PROJECT-22790943, KAKENHI-PROJECT-23390260
[Journal Article] Crucial role for autophagy in degranulation of mast cells2011
- Author(s)
  Ushio, et al
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 127 Issue: 5 Pages: 1267-1276
- DOI
  10.1016/j.jaci.2010.12.1078
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117717, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23590576, KAKENHI-PROJECT-23659404
[Journal Article] Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells2011
- Author(s)
  Kitamura N., et al
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: (未定)(in press) Issue: 3 Pages: 814-824
- DOI
  10.1016/j.jaci.2011.10.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791091, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-24591667
[Journal Article] Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.2010
- Author(s)
  Ohki M., Y.Ohki, M.Ishihara, C.Nishida, Y.Tashiro, H.Akiyama, H.Komiyama, L.R.Lund, A.Nitta, K.Yamada, Z.Zhu, H.Ogawa, H.Yagita,K.Okumura, H.Nakauchi, Z.Werb, B.Heissig, K.Hattori
- Journal Title
  
  Blood 115
  
  Pages: 4302-4312
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells.2010
- Author(s)
  Niyonsaba F., H.Ushio, M.Hara, H.Yokoi, M.Tominaga, K.Takamori, N.Kajiwara, H.Saito, I.Nagaoka, H.Ogawa, K.Okumura
- Journal Title
  
  J Immunol 184
  
  Pages: 3526-3534
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Staphylococcus aureus membrane and diacylated lipopeptide induce thymic stromal lymphopoietin in keratinocytes through the Toll-like receptor 2-Toll-like receptor 6 pathway.2010
- Author(s)
  Vu,A.T., T.Baba, X.Chen, T.A.Le, H.Kinoshita, Y.Xie, S.Kamijo, K.Hiramatsu, S.Ikeda, H.Ogawa, K.Okumura, T.Takai
- Journal Title
  
  J Allergy Clin Immunol 126
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] GATA2 and Sp1 positively regulate the c-kit promoter in mast cells.2010
- Author(s)
  Maeda K., C.Nishiyama, H.Ogawa, K.Okumura
- Journal Title
  
  J Immunol 185
  
  Pages: 4252-4260
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] TIM1 is an endogenous ligand for LMIR5/CD300b : LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.2010
- Author(s)
  Yamanishi Y., J.Kitaura, K.Izawa, A.Kaitani, Y.Komeno, M.Nakamura, S.Yamazaki, Y.Enomoto, T.Oki, H.Akiba, T.Abe, T.Komori, Y.Morikawa, H.Kiyonari, T.Takai, K.Okumura, T.Kitamura
- Journal Title
  
  J Exp Med 207
  
  Pages: 1501-1511
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Combination therapy of established tumors by antibodies targeting immune activating and suppressing molecules.2010
- Author(s)
  Takeda K., Y.Kojima, T.Uno, Y.Hayakawa, M.W.Teng, H.Yoshizawa, H.Yagita, F.Gejyo, K.Okumura, M.J.Smyth.
- Journal Title
  
  J Immunol 184
  
  Pages: 5493-5501
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.2009
- Author(s)
  Kinoshita H., T.Takai, T.A.Le, S.Kamijo, X.L.Wang, H.Ushio, M.Hara, J.Kawasaki, A.T.Vu, T.Ogawa, H.Gunawan, S.Ikeda, K.Okumura, H.Ogawa
- Journal Title
  
  J Allergy Clin Immunol 123
  
  Pages: 179-186
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Notch signaling confers antigen-presenting cell functions on mast cells.2009
- Author(s)
  Nakano N., C.Nishiyama, H.Yagita, A.Koyanagi, H.Akiba, S.Chiba, H.Ogawa, K.Okumura
- Journal Title
  
  J Allergy Clin Immunol 123
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] RANK-RANKL signaling pathway is critically involved in the function of CD4+CD25+ regulatory T cells in chronic colitis.2009
- Author(s)
  Totsuka T., T.Kanai, Y.Nemoto, T.Tomita, R.Okamoto, K.Tsuchiya, T.Nakamura, N.Sakamoto, H.Akiba, K.Okumura, H.Yagita, M.Watanabe
- Journal Title
  
  J Immunol 182
  
  Pages: 6079-6087
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] NKG2A inhibits invariant NKT cell activation in hepatic injury.2009
- Author(s)
  Kawamura T., K.Takeda, H.Kaneda, H.Matsumoto, Y.Hayakawa, D.H.Raulet, Y.Ikarashi, M.Kronenberg, H.Yagita, K.Kinoshita, T.Abo, K.Okumura, M.J.Smyth
- Journal Title
  
  J Immunol 182
  
  Pages: 250-258
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation.2009
- Author(s)
  Nakayama M., H.Akiba, K.Takeda, Y.Kojima, M.Hashiguchi, M.Azuma, H.Yagita, K.Okumura
- Journal Title
  
  Blood 113
  
  Pages: 3821-3830
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Watanabe Blockade of NKG2D signaling prevents the development of murine CD4+ T cell-mediated colitis2008
- Author(s)
  Ito, Y., T., Kanai, T., Totsuka, R., Okamoto, K., Tsuchiya, Y., Nemoto, A., Yoshioka, T., Tomita, T., Nagaishi, N., Sakamoto, T., Sakanishi, K., Okumura, H., Yagita, M
- Journal Title
  
  American journal of physiology 294
  
  Pages: 199-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Monomeric IgE and lipopolysaccharide synergistically prevent mast-cell apoptosis2008
- Author(s)
  Jayawardana, S., T., H. Ushio, F., Niyonsaba, S. P., Gondokaryono, H., Takenaka, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  Biochemical and biophysical research communications 365
  
  Pages: 137-142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] B7-H3 contributes to the development of pathogenic Th2 cells in a murine model of asthma.2008
- Author(s)
  Nagashima O., N.Harada, Y.Usui, T.Yamazaki, H.Yagita, K.Okumura, K.Takahashi, H.Akiba
- Journal Title
  
  J Immunol 181
  
  Pages: 4062-4071
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Two different transcription factors discriminate the -315C>T polymorphism of the Fc epsilon RI alpha gene : binding of Sp1 to -315C and of a high mobility group-related molecule to -315T.2008
- Author(s)
  Kanada S., N.Nakano, D.P.Potaczek, K.Maeda, N.Shimokawa, Y.Niwa, T.Fukai, M.Sanak, A.Szczeklik, H.Yagita, K.Okumura, H.Ogawa, C.Nishiyama
- Journal Title
  
  J Immunol 180
  
  Pages: 8204-8210
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Human umbilical cord epithelial cells express Notchl : implications for its epidermal-like differentiation2008
- Author(s)
  Ng, W., C., Nishiyama, M., Mizoguchi, N., Nakano, Y., Suga, S., Ikeda, S., Itoh, K., Kinoshita, K., Okumura., H., Ogawa
- Journal Title
  
  Journal of dermatological science 49
  
  Pages: 143-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Runx proteins are involved in regulation of CD 122, Ly49 family and IFN-gamma expression during NK cell differentiation2008
- Author(s)
  Ohno, S., T., Sato, K., Kohu, K., Takeda, K., Okumura, M., Satake, S., Habu
- Journal Title
  
  International immunology 20
  
  Pages: 71-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Role of Sp 1 in transcription of human ATP2A2 gene in keratinocytes2008
- Author(s)
  Takagi, A., C. Nishiyama, K., Maeda, T., Tokura, H., Kawada, S., Kanada, Y., Niwa, N., Nakano, N., Mayuzumi, M., Nishiyama, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  The Journal of investigative dermatology 128
  
  Pages: 96-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article]2008
- Author(s)
  Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Fress S, Ikeda H, Hynes NM, Cretney E, Yagita H, Sueyoshi N, Sato N, Nakanuma Y, Smyth MJ, Okumura K
- Journal Title
  
  Proc Natl Sci USA 105(31)
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590257
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.2008
- Author(s)
  Takeda K, Kojima Y, Ikejima K, Harada K, Yamashina S, Okumura K, Aoyama T, Frese s, Ikeda H, Hynes NM, Cretney E, Yagita H, Sueyoshi N, Sato N, Nakanuma Y, Smyth MJ, Okumura K
- Journal Title
  
  Proc Natl Acad Sci U S A 105(31)
  
  Pages: 10895-10900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590257
[Journal Article] Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease.2008
- Author(s)
  Takeda K., Y.Kojima, K.Ikejima, K.Harada, S.Yamashina, K.Okumura, T.Aoyama, S.Frese, H.Ikeda, N.M.Haynes, E.Cretney, H.Yagita, N.Sueyoshi, N.Sato, Y.Nakanuma, M.J.Smyth, K.Okumura
- Journal Title
  
  Proc Natl Acad Sci U S A 105
  
  Pages: 10895-10900
- Data Source
  KAKENHI-PROJECT-20390282
[Journal Article] Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells2008
- Author(s)
  Nakajima, A., Y., Kojima, M., Nakayama, H., Yagita, K., Okumura, H., Nakano
- Journal Title
  
  Oncogene 27
  
  Pages: 76-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] A possible role for TSLP in inflammatory arthritis2007
- Author(s)
  Koyama, K., T., Ozawa, K., Hatsushika, T., Ando, S., Takano, M., Wako, F., Suenaga, Y., Ohnuma, T., Ohba, R., Katoh, H., Sugiyama, Y., Hamada, H., Ogawa, K., Okumura, A., Nakao
- Journal Title
  
  Biochemical and biophysical research communications 357
  
  Pages: 99-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Targeting death-inducing receptors in cancer therapy2007
- Author(s)
  Takeda, K., J., Stagg, H., Yagita, K., Okumura, M. J., Smyth
- Journal Title
  
  Oncogene 26
  
  Pages: 3745-3757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Interleukin-12- and interferon-gamma-mediated natural killer cell activation by Agaricus blazei Murill2007
- Author(s)
  Yuminamochi, E., T., Koike, K., Takeda, I., Horiuchi, K., Okumura
- Journal Title
  
  Immunology 121
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Antibodies to T-cell Ig and mucin domain-containing proteins(Tim)-1 and -3 suppress the induction and progression of murine allergic conjunctivitis2007
- Author(s)
  Fukushima, A., T., Sumi, K., Fukuda, N., Kumagai, T., Nishida, H., Akiba, K., Okumura, H., Yagita, H., Ueno
- Journal Title
  
  Biochemical and biophysical research communications 353
  
  Pages: 211-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections2007
- Author(s)
  Nakano, N., C., Nishiyama, S., Kanada, Y., Niwa, N., Shimokawa, H., Ushio, M., Nishiyama, K., Okumura, H., Ogawa
- Journal Title
  
  Blood 109
  
  Pages: 4846-4855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] TACI regulates IgA production by APRIL in collaboration with HSPG2007
- Author(s)
  Sakurai, D., H., Hase, Y., Kanno, H., Kojima, K., Okumura, T., Kobata
- Journal Title
  
  Blood 109
  
  Pages: 2961-2967
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] TGF-beta type I receptor kinase inhibitor down-regulates rheumatoid synoviocytes and prevents the arthritis induced by type II collagen antibody2007
- Author(s)
  Sakuma, M., K., Hatsushika, K., Koyama, R., Katoh, T., Ando, Y., Watanabe, M., Wako, M., Kanzaki, S., Takano, H., Sugiyama, Y., Hamada, H., Ogawa, K., Okumura, A., Nakao
- Journal Title
  
  International immunology 19
  
  Pages: 117-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] T-cell Ig and mucin domain-containing protein(Tim)-2 regulates murine allergic conjunctivitis during the effector phase2007
- Author(s)
  Fukushima, A., T., Sumi, K., Fukuda, N., Kumagai, T., Nishida, K., Okumura, H., Akiba, H., Yagita, H., Ueno
- Journal Title
  
  Immunology letters 110
  
  Pages: 133-138
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Orally administered TGF-beta is biologically active in the intestinal mucosa and enhances oral tolerance2007
- Author(s)
  Ando, T., K., Hatsushika, M., Wako, T., Ohba, K., Koyama, Y., Ohnuma, R., Katoh, H., Ogawa, K., Okumura, J., Luo, T., Wyss-Coray, A., Nakao
- Journal Title
  
  The Journal of allergy and clinical immunology 120
  
  Pages: 916-923
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] The plasminogen fibrinolytic pathway is required for hematopoietic regeneration2007
- Author(s)
  Heissig, B., L. R., Lund, H., Akiyama, M., Ohki, Y., Morita, J., Romer, H., Nakauchi, K., Okumura, E., Ogawa, Z., Werb, K., Dano, K., Hattori
- Journal Title
  
  Cell stem cell 1
  
  Pages: 658-670
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Blockade of the OX40ligand prolongs corneal allograft survival2007
- Author(s)
  Hattori, T., Y., Usui, Y., Okunuki, Y., Sonoda, M., Usui, E., Takada, J., Mizuguchi, H., Yagita, K., Okumura, H., Akiba, M., Takeuchi
- Journal Title
  
  European journal of immunology 37
  
  Pages: 3597-3604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Antimicrobial peptides human beta-defensin(hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability2007
- Author(s)
  Chen, X., F., Niyonsaba, H., Ushio, M., Hara, H., Yokoi, K., Matsumoto, H., Saito, I., Nagaoka, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  European journal of immunology 37
  
  Pages: 434-444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] TACI attenuates antibody production costimulated by BAFF-R and CD402007
- Author(s)
  Sakurai, D., Y., Kanno, H., Hase, H., Kojima, K., Okumura, T., Kobata
- Journal Title
  
  European journal of immunology 37
  
  Pages: 110-118
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Combination antibody-based cancer immunotherapy2007
- Author(s)
  Takeda, K., K., Okumura, M. J., Smyth
- Journal Title
  
  Cancer science 98
  
  Pages: 1297-1302
- NAID
  10019998008
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] B7-H3 regulates the development of experimental allergic conjunctivitis in mice2007
- Author(s)
  Fukushima, A., T., Sumi, K., Fukuda, N., Kumagai, T., Nishida, T., Yamazaki, H., Akiba, K., Okumura, H., Yagita, H., Ueno
- Journal Title
  
  Immunology letters 113
  
  Pages: 52-57
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Cathelicidin LL-37 induces the generation of reactive oxygen species and release of human alpha-defensins from neutrophils2007
- Author(s)
  Zheng, Y., F., Niyonsaba, H., Ushio, I., Nagaoka, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  The British journal of dermatology 157
  
  Pages: 1124-1131
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] TNF receptor-associated factor 2-dependent canonical pathway is crucial for the development of Peyer's patches2007
- Author(s)
  Piao, J. H., H., Yoshida, W. C., Yeh, T., Doi, X., Xue, H., Yagita, K., Okumura, H., Nakano
- Journal Title
  
  J lmmunol 178
  
  Pages: 2272-2277
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Roles of programmed death-1(PD-1)/PD-1 ligands pathway in the development of murine acute myocarditis caused by coxsackievirus B32007
- Author(s)
  Seko, Y., H., Yagita, K., Okumura, M., Azuma, R., Nagai
- Journal Title
  
  Cardiovascular research 75
  
  Pages: 158-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] The extra domain A of fibronectin stimulates murine mast cells via toll-like receptor 42007
- Author(s)
  Gondokaryono, S. P., H., Ushio, F., Niyonsaba, M., Hara, H., Takenaka, S., T., Jayawardana, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  Journal of leukocyte biology 82
  
  Pages: 657-665
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Antimicrobial peptides human beta-defensins stimulate epidermal keratinocyte migration, proliferation and production of proinflammatory cytokines and chemokines2007
- Author(s)
  Niyonsaba, F., H., Ushio, N., Nakano, W., Ng, K., Sayama, K., Hashimoto, I., Nagaoka, K., Okumura, H., Ogawa
- Journal Title
  
  The Journal of investigative dermatology 127
  
  Pages: 594-604
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human NK-cell activity2007
- Author(s)
  Takeda, K., K., Okumura
- Journal Title
  
  The Journal of nutrition 137
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis2006
- Author(s)
  Kamata, K., S., Kamijo, A., Nakajima, A., Koyanagi, H., Kurosawa, H., Yagita, K., Okumura
- Journal Title
  
  J lmmunol 177
  
  Pages: 6433-6439
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] 2006. Ameliorating effect of saporin-conjugated anti-CD llb monoclonal antibody in a murine T-cell-mediated chronic colitis2006
- Author(s)
  Kanai, T., K., Uraushihara, T., Totsuka, Y., Nemoto, R., Fujii, T., Kawamura, S., Makita, D., Sawada, H., Yagita, K., Okumura, M., Watanabe
- Journal Title
  
  Journal of gastroenterology and hepatology 21
  
  Pages: 1136-1142
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Reduction of skin barrier function by proteolytic activity of a recombinant house dust mite major allergen Der f12006
- Author(s)
  Nakamura, T., Y., Hirasawa, T., Takai, K., Mitsuishi, M., Okuda, T., Kato, K., Okumura, S., Ikeda, H., Ogawa
- Journal Title
  
  The Journal of investigative dermatology 126
  
  Pages: 2719-2723
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] FOG-1 represses GATA-1-dependent FcepsilonRl beta-chain transcription : transcriptional mechanism of mast-cell-specific gene expression in mice2006
- Author(s)
  Maeda, K., C., Nishiyama, T., Tokura, H., Nakano, S., Kanada, M., Nishiyama, K., Okumura, H., Ogawa
- Journal Title
  
  Blood 108
  
  Pages: 262-269
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease2006
- Author(s)
  Oikawa, T., Y., Kamimura, H., Akiba, H., Yagita, K., Okumura, H., Takahashi, M., Zeniya, H., Tajiri, M., Azuma
- Journal Title
  
  J lmmuno 1177
  
  Pages: 4281-4287
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Crucial commitment of proteolytic activity of a purified recombinant major house dust mite allergen Der p1 to sensitization toward IgE and IgG responses2006
- Author(s)
  Kikuchi, Y., T., Takai, T., Kuhara, M., Ota, T., Kato, H., Hatanaka, S., Ichikawa, T., Tokura, H., Akiba, K., Mitsuishi, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  J lmmunol 177
  
  Pages: 1609-1617
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] 2006. B7-Hi-induced apoptosis as a mechanism of immune privilege of corneal allografts2006
- Author(s)
  Hori, J., M., Wang, M., Miyashita, K., Tanemoto, H., Takahashi, T., Takemori, K., Okumura, H., Yagita, M., Azuma
- Journal Title
  
  J lmmunol 177
  
  Pages: 5928-5935
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Human cathelicidin LL-37 increases vascular permeability in the skin via mast cell activation, and phosphorylates MAP kinases p38 and ERK in mast cells2006
- Author(s)
  Chen, X., F., Niyonsaba, H., Ushio, I., Nagaoka, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  Journal of dermatological science 43
  
  Pages: 63-66
- NAID
  10020549395
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] 2006. Eradication of established tumors in mice by a combination antibody-based therapy2006
- Author(s)
  Uno, T., K., Takeda, Y., Kojima, H., Yoshizawa, H., Akiba, R. S., Mittler, F., Gejyo, K., Okumura, H., Yagita, M. J., Smyth
- Journal Title
  
  Nature medicine 12
  
  Pages: 693-698
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody2006
- Author(s)
  Kamijo, S., A., Nakajima, K., Ikeda, K., Aoki, K., Ohya, H., Akiba, H., Yagita, K., Okumura
- Journal Title
  
  Biochemical and biophysical research communications 347
  
  Pages: 124-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Application of immunoreaction enhancer solutions to an enzyme-linked immunosorbent assay for antigen-specific IgE in mice immunized with recombinant major mite allergens or ovalbumin2006
- Author(s)
  Kikuchi, Y., T., Takai, M., Ota, T., Kato, K., Takeda, K., Mitsuishi, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  International archives of allergy and immunology 141
  
  Pages: 322-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Development of a whole cell vaccine for acute myeloid leukaemia2006
- Author(s)
  Cheuk, A., T., L., Chan, B., Czepulkowski, S. A., Berger, H., Yagita, K., Okumura, F., Farzaneh, G. J., Mufti, B. A., Guinn
- Journal Title
  
  Cancer Immunol Immunother 55
  
  Pages: 68-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Prolonged MHC class II expression and CIITA transcription in human keratinocytes2006
- Author(s)
  Takagi, A., C., Nishiyama, S., Kanada, Y., Niwa, K., Fukuyama, S., Ikeda, K., Okumura, H., Ogawa
- Journal Title
  
  Biochemical and biophysical research communications 347
  
  Pages: 388-393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Reactive oxygen species mediate crosstalk between NF-kappaB and JNK.2006
- Author(s)
  Nakano, H., A Nakajima, S.Sakon-Komazawa, J.H.Pino, X.Xue, K.Okumura
- Journal Title
  
  Cell Death Differ 13
  
  Pages: 730-737
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Resistance of infant leukemia with MLL rearrangement to tumor necrosis factor-related apoptosis-inducing ligand : a possible mechanism for poor sensitivity to antitumor immunity2006
- Author(s)
  Inukai, T., X., Zhang, M., Goto, K., Hirose, K., Uno, K., Akahane, A., Nemoto, K., Goi, H., Sato, K., Takahashi, H., Honna, K., Kagami, K., Nakamoto, H., Yagita, K., Okumura, T., Koyama-Okazaki, S., Nakazawa, K., Sugita
- Journal Title
  
  Leukemia 20
  
  Pages: 2119-2129
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] An antiapoptotic protein, c-FLIPL, directly binds to MKK7 and inhibits the JNK pathway2006
- Author(s)
  Nakajima, A., S., Komazawa-Sakon, M., Takekawa, T., Sasazuki, W. C., Yeh, H., Yagita, K., Okumura, H., Nakano
- Journal Title
  
  The EMBO journal 25
  
  Pages: 5549-5559
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Glycosylation of recombinant proforms of major house dust mite allergens Der p 1 and Der f 1 decelerates the speed of maturation2006
- Author(s)
  Takai, T., E., Mizuuchi, Y., Kikuchi, T., Nagamune, K., Okumura, H., Ogawa
- Journal Title
  
  International archives of allergy and immunology 139
  
  Pages: 181-187
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Journal Article] Beta2-microglobulin required for cell surface expression of blastocyst MHC.2005
- Author(s)
  Tanaka, T., T Ebata, A.Tajima, K.Kinoshita, K.Okumura, H.Yagita
- Journal Title
  
  Biochem Biophys Res Commun 332
  
  Pages: 311-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2.2005
- Author(s)
  Ota, T., K.Takeda, H.Akiba, Y.Hayakawa, K.Ogasawara, Y.Ikarashi, S.Miyake, H.Wakasugi, T.Yamamura, M.Kronenberg, D.H.Raulet, K.Kinoshita, H.Yagita, M.J.Smyth, K.Okumura
- Journal Title
  
  Blood 106
  
  Pages: 184-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Blockade of B7-H1 on macrophages suppresses CD4+ T cell proliferation by augmenting IFN-gamma-induced nitric oxide production.2005
- Author(s)
  Yamazaki, T., H.Akiba, A.Koyanagi, M.Azuma, H.Yagita, K.Okumura
- Journal Title
  
  J Immunol 175
  
  Pages: 1586-1592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Critical contribution of CD8O and CD86 to induction of anterior chamber-associated immune deviation.2005
- Author(s)
  Tsukahara, R., M.Takeuchi, H.Akiba, T.Kezuka, K.Takeda, Y.Usui, M.Usui, H.Yagita, K.Okumura
- Journal Title
  
  Int Immunol 17
  
  Pages: 523-530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] 2005.TWEAK mediates anti-tumor effect of tumor-infiltrating macrophage.2005
- Author(s)
  Kaduka, Y., K.Takeda, M.Nakayama, K.Kinoshita, H.Yagita, K.Okumura
- Journal Title
  
  Biochem Biophys Res Commun 331
  
  Pages: 384-390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells.2005
- Author(s)
  Kawamura, H., H.Yagita, T.Nisizawa, N.Izumi, C.Miyaji, R.E.Vance, D.H.Raulet, K.Okumura, T.Abo
- Journal Title
  
  Eur J Immunol 35
  
  Pages: 2358-2366
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] ICOS costimulates invariant NKT cell activation.2005
- Author(s)
  Kaneda, H., K.Takeda, T.Ota, Y.Kaduka, H.Akiba, Y.Ikarashi, H.Wakasugi, M.Kronenberg, K.Kinoshita, H.Yagita, K.Okumura
- Journal Title
  
  Biochem Biophys Res Commun 327
  
  Pages: 201-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL identifies immature natural killer cells in newborn mice and adult mouse liver.2005
- Author(s)
  Takeda, K., E.Cretney, Y.Hayakawa, T.Ota, H.Akiba, K.Ogasawara, H.Yagita, K.Kinoshita, K.Okumura, M.J.Smyth
- Journal Title
  
  Blood 105
  
  Pages: 2082-2089
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha.2005
- Author(s)
  Xue, X., J.H.Piao, A.Nakajima, S.Sakon-Komazawa, Y.Kojima, K.Mori, H.Yagita, K.Okumura, H.Harding, H.Nakano
- Journal Title
  
  J Biol Chem 280
  
  Pages: 33917-33925
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Renal allograft rejection is prevented by adoptive transfer of anergic T cells in nonhuman primates.2005
- Author(s)
  Bashuda, H., M.Kimikawa, K.Seino, Y.Kato, F.Ono, A.Shimizu, H.Yagita, S.Teraoka, K.Okumura
- Journal Title
  
  J Clin Invest 115
  
  Pages: 1896-1902
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Immune responses against a single CD8+-T-cell epitope induced by virus vector vaccination can successfully control Trypanosoma cruzi infection.2005
- Author(s)
  Miyahira, Y., Y.Takashima, S.Kobayashi, Y.Matsumoto, T.Takeuchi, M.Ohyanagi-Hara, A.Yoshida, A.Ohwada, H.Akiba, H.Yagita, K.Okumura, H.Ogawa
- Journal Title
  
  Infect Immun 73
  
  Pages: 7356-7365
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] 2005.Regulation of murine chronic colitis by CD4+CD25-programmed death-1+ T cells.2005
- Author(s)
  Totsuka, T., T.Kanai, S.Makita, R.Fujii, Y.Nemoto, S.Oshima, R.Okamoto, A.Koyanagi, H.Akiba, K.Okumura, H.Yagita, M.Watanabe
- Journal Title
  
  Eur J Immunol 35
  
  Pages: 1773-1785
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.2005
- Author(s)
  Akiba, H., K.Takeda, Y.Kojima, Y.Usui, N.Harada, T.Yamazaki, J.Ma, K.Tezuka, H.Yagita, K.Okumura
- Journal Title
  
  J Immunol 175
  
  Pages: 2340-2348
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Induction of RANTES by TWEAK/Fn14 interaction in human keratinocytes.2004
- Author(s)
  Jin, L., A.Nakao, M.Nakayama, N.Yamaguchi, Y.Kojima, N.Nakano, R.Tsuboi, K.Okumura, H.Yagita, H.Ogawa
- Journal Title
  
  J Invest Dermatol 122
  
  Pages: 1175-1179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Contribution of CD1d-unrestricted hepatic DX5+ NKT cells to liver injury in Plasmodium berghei-parasitized erythrocyte-injected mice.2004
- Author(s)
  Adachi, K., H.Tsutsui, E.Seki, H.Nakano, K.Takeda, K.Okumura, L.Van Kaer, K.Nakanishi
- Journal Title
  
  Int Immunol 16
  
  Pages: 787-798
- NAID
  10013085831
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] CAM and NK Cells.2004
- Author(s)
  Takeda, K., K.Okumura
- Journal Title
  
  Evid Based Complement Alternat Med 1
  
  Pages: 17-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS.2004
- Author(s)
  Sasazuki, T., T.Okazaki, K.Tada, S.Sakon-Komazawa, M.Katano, M.Tanaka, H.Yagita, K.Okumura, N.Tominaga, Y.Hayashizaki, Y.Okazaki, H.Nakano
- Journal Title
  
  Mol Immunol 41
  
  Pages: 547-551
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TRAIL and its receptors as targets for cancer therapy.2004
- Author(s)
  Yagita, H., K.Takeda, Y.Hayakawa, M.J.Smyth, K.Okumura
- Journal Title
  
  Cancer Sci 95
  
  Pages: 777-783
- NAID
  10014170265
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy.2004
- Author(s)
  Takeda, K., N.Yamaguchi, H.Akiba, Y.Kojima, Y.Hayakawa, J.E.Tanner, T.J.Sayers, N.Seki, K.Okumura, H.Yagita, M.J.Smyth
- Journal Title
  
  J Exp Med 199
  
  Pages: 437-448
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Inducible costimulator-dependent IL-10 production by regulatory T cells specific for self-antigen.2004
- Author(s)
  Kohyama, M., D.Sugahara, S.Sugiyama, H.agita, K.Okumura, N.Hozumi
- Journal Title
  
  Proc Natl Acad Sci USA 101
  
  Pages: 4192-4197
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] TWEAK/Fn14 interaction stimulates human bronchial epithelial cells to produce IL-8 and GM-CSF.2004
- Author(s)
  Xu, H., A.Okamoto, J.Ichikawa, T.Ando, K.Tasaka, K.Masuyama, H.Ogawa, H.Yagita, K.Okumura, A.Nakao
- Journal Title
  
  Biochem Biophys Res Commun 318
  
  Pages: 422-427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] Sensitization of human glioblastomas to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by NF-kappaB inhibitors.2004
- Author(s)
  Kasuga, C., T.Ebata, N.Kayagaki, H.Yagita, M.Hishii, H.Arai, K.Sato, K.Okumura
- Journal Title
  
  Cancer Sci 95
  
  Pages: 840-844
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390120
[Journal Article] 2006. The role of the ICOS/B7RP-1 T cell costimulatory pathway in murine experimental autoimmune uveoretinitis
- Author(s)
  Usui, Y., H., Akiba, M., Takeuchi, T., Kezuka, A., Takeuchi, T., Hattori, Y., Okunuki, T., Yamazaki, H., Yagita, M., Usui, K., Okumura
- Journal Title
  
  European journal of immunology 36
  
  Pages: 3071-3081
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390292
[Presentation] 肝移植における移植後免疫寛容の未来2022
- Author(s)
  奥村康
- Organizer
  第40回　肝移植学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00544
[Presentation] 免疫治療の新戦略2022
- Author(s)
  奥村康
- Organizer
  第58回日本移植学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H00544
[Presentation] A clinical trial of cell therapy-based tolerance induction in living donor liver transplantation: Long-term follow-up results2016
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Okumura K, Todo S
- Organizer
  26th International Congress of The Transplantation Society
- Place of Presentation
  Hong Kong, China
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] The role of leukocyte mono-immunoglobulin -like receptor 8 (LMIR8)/CLM-6 in plasmacytoid dendritic cell (pDC)2016
- Author(s)
  KAITANI Ayako, IZAWA Kumi, MAEHARA Akie, ISOBE Masamichi, Takamori Ayako, Uchida Shino, NAKANO Nobuhiro, MAEDA Keiko, ANDO Tomoaki, OKUMURA Ko, KITAMURA Toshio, KITAURA Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] TIM-3 regulates pulmonary fibrosis through apoptotic cell clearance2016
- Author(s)
  ISSHIKI Takuma, AKIBA Hisaya, NAKAYAMA Masafumi, HARADA Norihiro, OKUMURA Ko, MIYAKE Sachiko
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] 食物アレルギーモデルマウスを用いたNotchシグナルによるマスト細胞の機能制御2016
- Author(s)
  本庄明日香、中野信浩、山崎晋、森真理、原むつ子、大塚宜一、奥村康、清水俊明
- Organizer
  第65回日本アレルギー学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] A critical role of ceramide-CD300f interaction in septic peritonitis2016
- Author(s)
  IZAWA Kumi, MAEHARA Akie, ISOBE Masamichi, KAITANI Ayako, NAKANO Nobuhiro, MAEDA Keiko, Takamori Ayako, OKUMURA Ko, KITAMURA Toshio, KITAURA Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] Leukocyte mono-immunoglobulin-like receptor 6 (LMIR6) is an activating receptor expressed in patrolling monocytes2016
- Author(s)
  ISOBE Masamichi, Takamori Ayako, IZAWA Kumi, MAEHARA Akie, KAITANI Ayako, Uchida Shino, NAKANO Nobuhiro, MAEDA Keiko, ANDO Tomoaki, OKUMURA Ko, KITAMURA Toshio, KITAURA Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] 生体肝移植における制御性T細胞を用いた免疫寛容誘導法の臨床試験2016
- Author(s)
  山下健一郎、財津雅昭、後藤了一、長津明久、鈴木友己、嶋村　剛、神山俊哉、場集田　寿、奥村　康、藤堂　省
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  あわぎんホール（徳島県徳島市）
- Year and Date
  2016-07-14
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] フィラグリン発現量の初代培養ヒト鼻粘膜上皮における変化2016
- Author(s)
  三輪正人、Sharif Hasan、廣瀬壮、中島規幸、三輪真由美、大久保公裕、奥村康
- Organizer
  第65回日本アレルギー学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] マスト細胞に発現する活性化型受容体LMIR7のアレルギー反応における役割2016
- Author(s)
  伊沢久未、奥村康、北村俊雄、北浦次郎
- Organizer
  第65回日本アレルギー学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] Inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia2016
- Author(s)
  NAKANO Nobuhiro, HONJO Asuka, YAMAZAKI Susumu, OHTSUKA Yoshikazu, YAGITA Hideo, SHIMIZU Toshiaki, OKUMURA Ko, OGAWA hideoki
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] Notch signaling induces expression of MHC class II and CX3CR1 on mast cells2016
- Author(s)
  HOMMA Yuki, NAKANO Nobuhiro, OKUMURA Ko, OGAWA Hideoki
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] Contribution of IL-17A to papain-induced allergic responses in the skin and production of IL-17A from dendritic epidermal T cells in the papain-exposed skin2016
- Author(s)
  KAMIJO Seiji, NAKAE Susumu, OGAWA Hideoki, OKUMURA Ko, TAKAI Toshiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] CD300f suppresses LPS-induced skin inflammation2016
- Author(s)
  Watanabe Daiki, IZAWA Kumi, KAITANI Ayako, MAEHARA Akie, ISOBE Masamichi, Takamori Ayako, Uchida Shino, NAKANO Nobuhiro, MAEDA Keiko, ANDO Tomoaki, OKUMURA Ko, KITAMURA Toshio, KITAURA Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] アレルゲン，LPSおよびサイトカイン刺激による好塩基球のIL-4産生はFc受容体γ鎖に依存する2016
- Author(s)
  上條清嗣、布村聡、羅智靖、金口泰彦、鈴木祐介、小川秀興、奥村康、高井敏朗
- Organizer
  第65回日本アレルギー学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] GATA2 is involved in the expression of the decoy receptor for IL-33 by binding to the proximal promoter with chromosomal loop formation2016
- Author(s)
  KASAKURA Kazumi, YASHIRO Takuya, HARA Mutsuko, OKUMURA Ko, NISHIYAMA Chiharu
- Organizer
  第45回日本免疫学会
- Place of Presentation
  沖縄コンベンションセンター、ラグナガーデンホテル
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293087
[Presentation] A Clinical trial of cell therapy-based tolerance induction in living donor liver transplantation: An update2015
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  17th Congress of the European Society for Organ Transplantation
- Place of Presentation
  Brussels, Belgium
- Year and Date
  2015-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 樹状細胞におけるOX40L発現制御機構の解析2014
- Author(s)
  八代拓也, 奥村康, 西山千春
- Organizer
  日本農芸化学会 2014
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Inducion of Operational Tolerance by a Cell Therapy using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  World Transplant Congress 2014
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2014-07-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] GATA2によるマスト細胞のST2遺伝子発現制御機構2014
- Author(s)
  笠倉和巳, 八代拓也, 奥村康,　西山千春
- Organizer
  日本農芸化学会 2014
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] 粘膜型マスト細胞分化におけるNotchシグナルとIL-3シグナルの協調作用2014
- Author(s)
  中野信浩, 西山千春, 奥村康, 小川秀興
- Organizer
  日本農芸化学会 2014
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] A clinical trial of cell-therapy based on donor antigen-pulsed regulatory T cells for induction of operational tolerance in living donor liver transplantation2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Demetris AJ, Bashuda H, Okumura K, Todo S
- Organizer
  The 3rd International Conference on Immune Tolerance 2014
- Place of Presentation
  Amsterdam, Netherlands
- Year and Date
  2014-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] 抗CD80抗体、抗CD86抗体下共培養により誘導される免疫抑制性細胞の同定2014
- Author(s)
  長津明久、山下健一郎、江本　慎、旭　火華、財津雅昭、小倉正臣、小野　仁、常俊雄介、後藤了一、五十嵐瑠美、場集田　寿、奥村　康、武冨紹信、藤堂　省
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-04-03
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] Successful Withdrawal of Immunosuppression by a Cell Therapy Using Donor Ag-pulsed Tregs in Living Donor Liver Transplantation: An Update on Clinical Trial2014
- Author(s)
  Yamashita K, Goto R, Zaitsu M, Nagatsu A, Oura T, Watanabe M, Aoyagi T, Suzuki T, Shimamura T, Kamiyama T, Sato N, Sugita J, Hatanaka K, Bashuda H, Okumura K, Todo S
- Organizer
  2014 Joint International Congress of ILTS, ELITA & LICAGE
- Place of Presentation
  London, UK
- Year and Date
  2014-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253068
[Presentation] Involvement of transcription factors PU.1, GATA1 and GATA2 in the expression and function of human FcepsilonRI on mast cells2013
- Author(s)
  C. Nishiyama, E. Inage, K. Kasakura, T. Yashiro, M. Hara, H. Saito, T. Shimizu, H. Ogawa, K. Okumura
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Soluble form of TIM-4 regulates mast cell activation by binding to LMIR5 and TIM-3.2013
- Author(s)
  KAMACHI Fumitaka, HARADA Norihiro, NISHIYAMA Chiharu, IZAWA Kumi, KITAURA Jiro, OKUMURA Ko, MIYAKE Sachiko, AKIBA Hisaya
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Inhibitory receptor PIR-B is exploited by Staphylococcus aureus for virulence.2013
- Author(s)
  NAKAYAMA Masafumi, David M. UNDERHILL, NAKAMURA Kyohei, YAG1TA Hideo, OKUMURA Ko, TAKAI Toshiyuki, Alan ADEREM, OGASAWARA Kouetsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Ceramide and sphingomyelin are physiological ligans for human LMIR3/CD300f that negatively regulates FceRI-mediated activation of mast cell.2013
- Author(s)
  IZAWA Kumi, ISOBE Masamichi, MATSUKAWA Toshihiro, MAEHARA Akie, YAMANISHI Yoshinori, TAKAHASHI Mariko, KAITANI Ayako, OKUMURA Ko, KITAMURA Toshio, KITAURA Jiro
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] NotchシグナルはIL-3存在下において粘膜型マスト細胞の分化を促進する2013
- Author(s)
  中野信浩, 西山千春, 奥村康, 小川秀興
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  ホテルニューオータニ、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Notch1 signaling confers antigen-presenting functions on mast cells2013
- Author(s)
  N. Nakano, C. Nishiyama, H. Yagita, K. Okumura, H. Ogawa
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Regulation of contact hypersensitivity by Interleukin-21.2013
- Author(s)
  SHIMURA Eri, OKUMURA Ko, NAKAE Susumu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] IL-36 cytokines enhance the production of host defense peptides LL-37 and psoriasin by human keratinocytes through activation of MAPKs and NF-kB2013
- Author(s)
  Akiyama T, Nguyen TT, Niyonsaba F, Smithrithee R, Kiatsurayanon C, Ushio H, Okumura K, Ogawa H, Ikeda S
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] TLRリガンド及びサイトカイン刺激はヒトケラチノサイトにlong TSLP mRNA発現を誘導する2013
- Author(s)
  高井敏朗, 謝陽, 陳雪, 原むつ子, 上條清嗣, 小川秀興, 奥村康
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  ホテルニューオータニ、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Serial transfere of anergy status induced by TSST-1 into newly stimulated T cells2013
- Author(s)
  N. Negishi, T. Sato, Y. Kametani, S. Hori, K. Okumura, S. Habu
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Human b-defensin-3 improves the epithelial tight junction (TJ) barrier through activation of glycogen synthase kinase-3 (GSK-3) and protein kinase C (PKC)2013
- Author(s)
  Kiatsurayanon C, Niyonsaba F, Smithrithee R, Nguyen TT, Akiyama T, Ushio H, Ikeda S, Okumura K, Ogawa H
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] IL-33-mediated innate response and adaptive immune cells contribute to maximum responses of protease allergen-induced allergic airway inflammation2013
- Author(s)
  S. Kamijo, T. Takai, M. Hara, A. Matsuda, H. Saito, S. Nakae, K. Sudo, S. Ichikawa, H. Ogawa, K. Okumura
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Involvement of commensal bacteria in thymic Aire expression2013
- Author(s)
  A. Nakajima, N. Negishi, H. Tsurui, M. Nanno, H. Yagita, K. Okumura, S. Habu
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] サイトカインおよび2本鎖RNA刺激に対するケラチノサイト応答の、ヒト抗菌ペプチドLL-37による修飾2013
- Author(s)
  高井敏朗, 陳雪, 謝陽, ニヨンサバフランソワ, 原むつ子, 上條清嗣, 小川秀興, 奥村康
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  ホテルニューオータニ、東京
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Anti-TIM-4 mAb ameliorates allergic lung inflammation by inhibiting TIM-4-mediated mast cell stimulation2013
- Author(s)
  F. Kamachi, M. Hara, N. Harada, Y. Katsura, Y. Kojima, K. Izawa, C. Nishiyama, K. Okumura, H. Akiba
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] PU.1 regulates CCR7 expression in dendritic cells2013
- Author(s)
  T. Yashiro, M. Hara, K. Okumura, C. Nishiyama
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Contribution of IL-33 to allergic airway inflammation in mice sensitized subcutaneously and challenged intranasally with cysteine protease allergen.2013
- Author(s)
  KAMIJO Seiji, TAKAI Toshiro, HARA Mutsuko, MATSUDA Hironori, MATSUDA Akira, SAITO Hirohisa, NAKAE Susumu, ICHlKAWA Saori, OGAWA Hideoki, OKUMURA Ko
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Synthetic immunomodulatory peptides IDR-HH2, IDR-1002 and IDR-1018 regulate neutrophil functions2013
- Author(s)
  F. Niyonsaba, L. Madera, K. Okumura, H. Ogawa, R. E. W. Hancock
- Organizer
  15th International Congress of Immunology
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Effects of human β-defensins on interleukin-37 production by human keratinocytes2013
- Author(s)
  Smithrithee R, Niyonsaba F, Kiatsurayanon C, Nguyen TT, Akiyama T, Ushio H, Ikeda S, Okumura K, Ogawa H
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Characterization of virus recognition receptors: RIG-1-like receptors (RLRs) of mast cells2013
- Author(s)
  Takeuchi M, Fukuda M, Ushio H, Kawasaki J, Niyonsaba F, Okumura K, Ikeda S, Ogawa H
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation] Involvement of commensal bacteria in thymic Aire expression.2013
- Author(s)
  NAKAJIMA Akihito, NEGISHI Naoko, TSURUI Hiromichi, NANNO Masanobu, YAGITA Hideo, OKUMURA Ko, HABU Sonoko
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ、千葉市
- Data Source
  KAKENHI-PROJECT-23390260
[Presentation]2008
- Author(s)
  Takeda K, Kojima Y, Yagita H, Smyth MJ, Okumura K
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590257
[Presentation]2008
- Author(s)
  Kojima Y, Takeda K, Yagita H, Smyth MJ, Okumura K
- Organizer
  第38回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-19590257

1. YAGITA Hideo (30182306)

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Okumura Ko 奥村 康

OKUMURA Ko 奥村 康

Research Projects

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Multidimensional Analysis of operationally tolerance in living donor liver transplant patientsPrincipal Investigator

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Immune regulation on autoimmune and allergic diseases by the TIM family moleculesPrincipal Investigator

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Development of the antibody medical treatment to autoimmune and asthmatic diseases based on new target molecule.Principal Investigator

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Development of strategy to treat allergic diseases via targeting surface molecules on lymphocytes and intracellular signaling moleculesPrincipal Investigator

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Statistical analyses of allergy-related polymorphismsPrincipal Investigator

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Functional analysis of costimulatory molecules for autoimmune diseasesPrincipal Investigator

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REGULATION OF TUMOR VESSEL FORMATION BY THE IMMUNE SYSTEMPrincipal Investigator

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Okumura Ko 奥村康

OKUMURA Ko 奥村康