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YAMADA Nobuhiro  山田 信博

ORCIDConnect your ORCID iD *help
Researcher Number 40200729
Other IDs
Affiliation (based on the past Project Information) *help 2011: 筑波大学, 学長
2007 – 2008: University of Tsukuba, GraduateSchool of Comprehensive Human Sciences, Professor
2006: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Professor, 大学院人間総合科学研究所, 教授
2005 – 2006: 筑波大学, 大学院人間総合科学研究科, 教授
2004 – 2005: 筑波大学, 大学院・人間総合科学研究科, 教授 … More
2004: 筑波大学, 臨床医学系, 教授
2003 – 2004: 筑波大学, 医学部, 教授
1999 – 2002: 筑波大学, 臨床医学系, 教授
2001: Tsukuba University, Internal Medicine, Professor, 医学部, 教授
2000: 筑波大学, 臨床医学系内科, 教授
2000: 筑波大学, 附属病院, 教授
1999: 筑波大学, 医学研究科, 教授
1996 – 1999: University of Tokyo, Faculty of Medicine, Associate Prof., 医学部・附属病院, 助教授
1998: 東京大学, 医学部・付属病院, 助教授
1996 – 1998: 東京大学, 医学部附属病院, 助教授
1997: 東京大学, 医学部付属病院, 助教授
1995: University of Tokyo, Faculty of Medicine, Associate Prof., 医学部(病), 助教授
1994: 東京大学, 医学部(病), 講師
1990 – 1993: 東京大学, 医学部(病), 助手
1988 – 1993: 東京大学, 医学部, 助手
1992: 東京大学, 医学部・(病), 助手
1991: 東京大学, 医学部・(病)・当手
1990: Faculty of Medicine, University of Tokyo, Assistant Prof., 医学部・附属病院, 助手
1989: 東京大学, 医学部(病)・第三内科, 助手
1989: 東京大学, 医学部(病)第三内科, 助手 Less
Review Section/Research Field
Principal Investigator
内分泌・代謝学 / Metabolomics / Metabolomics / Biological Sciences
Except Principal Investigator
Metabolomics / 内分泌・代謝学 / Hematology / Sports science / Pathological medical chemistry / General surgery / Digestive surgery / Applied health science / Biological Sciences
Keywords
Principal Investigator
動脈硬化 / インスリン抵抗性 / 糖尿病 / アポE / atherosclerosis / M-CSF / 肥満 / トランスジェニックマウス / SREBP / 発生工学 … More / 脂肪細胞 / 高脂血症 / transcription factor / メタボリックシンドローム / insulin resistance / ACAT / Atheroscherosis / Molecular engineering / ノックアウトマウス / LPL / 動脈硬化症 / 平滑筋細胞 / マクロファージ / 遺伝子治療 / 合併症 / コレステロール / WHHLウサギ / コレステロ-ル / リポ蛋白 / LDLレセプタ- / diabetes mellitus / energy metabolism / metabolic syndrome / エネルギー代謝 / 転写調節因子 / Diabetes / Insulin sensitivity / Metabolic syndrome / 転写因子 / cell differentiation / CDK inhibitor / cell cycle / Atherosclerosis / シグナル伝達 / アポトーシス / 細胞分化 / CDK阻害因子 / 細胞周期 / transcription / fatty acid / 脂肪酸 / knockout mouse / hormone-sensitive lipase / obesity / ホルモン感受性リパーゼ / smooth / macrophage / foam cell / 泡沫細胞 / Hormone-sensitive lipase / Gene targeting / 遺伝子ターゲティング / 分子工学 / gene therapy / LDL receptor / Apo E / ジーンターゲティング / リポタンパクリパーゼ / LDL受容体 / LDLレセプター / Smooth musclecell / Macrophage / cytokine / スキャベンジャ-受容体 / マクロファ-ジ / MーCSF / サイトカイン / アポB100 / トランスレーショナルリサーチ / 科学研究費 / トランスレーションリサーチ / 基礎医学研究 / 臨床医学研究 / ストレス応答 / 腫瘍抑制因子 / p53 / 骨髄移植 / 分泌タンパク / DNAチップ / 血管合併症 / 染色体 / QTL / SHR / 遺伝子 / 高血圧 / インスリン / 遺伝子診断 / β-APP / アポE4 / 痴呆 / アルツハイマー病 / リポタンパク / 酵素 / 遺伝子変異 / 脂質代謝 / アポリポ蛋白E / α_2マクログロブリン / LRP / アポEレセプタ- / 神経再生 / 糖尿病性神経症 / アポリポ蛋白 … More
Except Principal Investigator
コレステロール / ノックアウトマウス / マクロファージ / 酸化LDL / 動脈硬化 / Atherosclerosis / Cholesterol / HDL / 糖尿病 / アポトーシス / プラーク / 血管新生 / 血管内皮細胞 / PPARδ / CRP / 脂質代謝 / 遺伝子改変 / Portocaval shunt / Animal model / QTL / Galectin-3 / RAGE / AGE / 遊離脂肪酸 / 膵臓移植 / インスリン / ジーンターゲティング / Triglyceride / 高脂血症 / ノックアウアトマウス / トリグリセリド / アデノウイルス / Bcl2 / リポタンパクリパーゼ / LDLレセプター / トランスジェニックマウス / コレステロール逆転送系 / リゾフォスファチジルコリン / Oxidized LDL / Macrophages / LDL / 肥満 / 中性脂肪 / Bcl-2 / オキシステロール / 細胞死 / アポリポタンパクE / 肝臓 / Aplastic anemia / Bone marrow transplantation / Leukemia / Hematopoietic growth factors / Neutropenia / Colony-stimulating factor / コロニー刺激因子 / 造血幹細胞 / エリスロポエチン / インタ-ロイキンー1 / インタ-ロイキンー3 / GMーCSF / MーCSF / GーCSF / 再生不良性貧血 / 骨髄移植 / 白血病 / コロニ-刺激因子 / 好中球減少症 / 造血因子 / diabetes mellitus / exercise tolerance / skeletal muscle / PPARdelta / 糖代謝 / 有酸素運動 / 運動耐容能 / 骨格筋 / Inflammation / Plaque / Hypercholesterolemia / Transgenic rabbits / 遺伝子導入 / 動物モデル / C-反応蛋白 / 炎症 / 実験モデル / C反応性蛋白 / 遺伝子改変ウサギ / Free fatty acid / Mesocaval shunt / TGSR : triglyceride secretion rate / 高インスリン血症 / TGSR:triglyceride secretion rate / 下大静脈 / 上腸間膜静脈 / Mesocaal shunt / Chromosome 9 / Gene / Insulin resistance / キヌレニン / 高血圧 / ラット / QTL解析 / SHR / 9番染色体 / モデル動物 / 遺伝子 / インスリン抵抗性 / Reverse Cholesterol Transport / Scavenger Receptor / AGE Receptor / Maillard Reaction endproduct / Diabetic Complications / スカベンジャー受容体 / AGE受容体 / メイラード反応後期生成物 / 糖尿病合併症 / catecholamoine / Free fatty acids / Infertility / Triacylglycerol / Hormone-sensitive lipase / Adipocytes / Obesity / リパーゼ / カテコラミン / 不妊 / ホルモン感受性リパーゼ / 脂肪細胞 / Bcl2 (anti-apoptotic gene) / adenovirus / insulin / transplantation / pancreas / 拒絶反応 / Bcl_2 / アデノウィルス / 膵移植 / Neural tube defect / Farneso1 / Hedgehog / Knockout mouse / Gene targeting / Squalene synthase / Development / キメラマウス / ES細胞 / ターゲティング / スクアレン合成酵素 / HMGCoA還元酵素 / 発生分化 / 神経管閉鎖不全 / ヘッジホッグ / 先天奇形 / スクワレン合成酵素 / スクワレン / Trasgenic / Knockout / Lipoprotein lipase / Apolipoprotein / Lipoprotein / 細胞間質 / レムナント / トランスジェニック / ノックアウト / アポタンパク / リポタンパク / Adhesion molecule / Phenotypic conversion / Vascular smooth muscle cell / Angiogenesis / Vasculogenesis / Vascular endothelial cell / 酸化LDL受容体 / ずり応力 / LOX-1 / CD36 / 接着分子 / 形質転換 / 血管平滑筋細胞 / 血管形成 / 粥状動脈硬化 / asiaoglycoprotein receptor / apolipoprotein E / low density lipoprotein receptor / lipoprotein lipase / knockout mice / transgenic mice / familial hypercholesterolemia / gene therapy / コレステロール 7α-ヒドロキシラーゼ / 肝幹細胞 / コレステロール7α水酸化酵素 / 相同的組換え / 移植 / シアル酸 / ガラクトース / アシアロ糖蛋白受容体 / アシアロ糖タンパクレセプター / アポリポタンパク / 家族性高コレステロール血症 / 遺伝子治療 / Small G Protein / 増殖因子 / VLDL容体 / VLDL受容体 / Rho / SDMF / CETP / M-CSF / Smooth muscle cell / WHHL rabbit / 泡沫細胞 / リポタンパクリパ-ゼ / マクロファ-ジ / 平滑筋細胞 / WHHLウサギ / ヒストリカル・コホート / メタアナリシス / 生活習慣病 / 生活習慣改善 / 健康寿命 / 生活習慣病・科学的エビデンス / メタボリックシンドローム / エネルギー代謝 / 転写調節 / HMG-CoA還元酵素 / メバロン酸 / ミトコンドリア / caspase 3 / CPP32 / カイロミクロンレムナント、 / トリグリセリド、 / リポタンパクリパーゼ、 / LDLレセプター、 / ノックアウトマウス、 / 動脈硬化、 / リポタンパク代謝、 / thymidine phosphorylase / 燐酸化 / (血小板由来血管内皮細胞増殖因子) / PD-ECGF / 血小板由来血管内皮細胞増殖因子 Less
  • Research Projects

    (45 results)
  • Research Products

    (130 results)
  • Co-Researchers

    (69 People)
  •  脂質合成系調節転写因子SREBP-1/2の標的配列特異性を決定する共因子の解明

    • Principal Investigator
      島野 仁
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Establishing clinical evidence for prevention of lifestyle-related disease and lifestyle intervention

    • Principal Investigator
      SONE Hirohito
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied health science
    • Research Institution
      University of Tsukuba
      Ochanomizu University
  •  Global survey on clinical research supporting and promoting system, aiming Japanese clinical research improvement.Principal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Special Purposes
    • Research Institution
      University of Tsukuba
  •  Transcriptional regulation of energy metabolism in metabolic syndrome.Principal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  Establishment of an animal model for muscle-specific overexpression of peroxisome proliferator-activated receptor (PPAR) δ and analysis of the effect of skeletal muscle PPAR δ on exercise tolerance and glucose metabolism

    • Principal Investigator
      SUZUKI Hiroaki, 飯田 薫子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Sports science
    • Research Institution
      University of Tsukuba
  •  腫瘍抑制因子p53活性化によるインスリン抵抗性発症の新しい分子機構の解明Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  Elucidation of C-reactive proteins in atherosclerosis

    • Principal Investigator
      FAN Jianglin
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Yamanashi
      University of Tsukuba
  •  Animal model for metabolic syndrome and its molecular basis.Principal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  Liver atrophy and Lipid metabolism after mesocaval and portocaval shunt in the rats

    • Principal Investigator
      ABE Hideki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
  •  糖尿病性血管合併症の発症に関わる細胞外分泌タンパク遺伝子の同定Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  骨髄移植によるインスリン抵抗性および肥満治療の試みと脂肪幹細胞の単離Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  糖尿病性血管合併症に特異的な遺伝子マーカーの分離同定Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Regulation of signaling pathway, cell cycle, and cell growth in atherosclerosisPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  病態モデル動物を用いた動脈硬化及びインスリン抵抗性遺伝子マップの作成Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Genetic analysis of the molecular basis of insulin resistance both in animal models and in humans.

    • Principal Investigator
      GOTODA Takanari
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Tokyo Woman's Medical University
      The University of Tokyo
  •  Roles of fatty acids in pathogenesis of insulin resisitance and atherosclerosisPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      University of Tsukuba
  •  Transgenic study on the heterogeneity of intacellular triacylglycerol lipase

    • Principal Investigator
      ISHIBASHI Shun
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      University of Tokyo
  •  Role of AGE Receptors in Diabetic Complications

    • Principal Investigator
      HORIUCHI Seikoh
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Metabolomics
    • Research Institution
      Kumamoto University
  •  自然高血圧発症ラット(SHR)におけるインスリン抵抗性発現の原因遺伝子の同定Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  アポトーシスの誘導と死細胞除去におけるオキシステロールの役割

    • Principal Investigator
      石橋 俊
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Development of a novel animal model to investigate the role of cholesterol metabolism in the development and differentiation

    • Principal Investigator
      ISHIBASHI Shun
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo
  •  Adenovirus-mediated anti-apoptotic gene (bcl-2) transfer in the transplant pancreas

    • Principal Investigator
      MAKUUCHI Masatoshi, 青柳 信嘉
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tokyo University
  •  プラークの形成と破綻における泡沫細胞の細胞死の役割を解明するためのモデルの樹立

    • Principal Investigator
      石橋 俊
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  糖尿病性血管合併症に特異的な遺伝子マーカーの分離同定Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Molecular Mechanism of Atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      KYOTO UNIVERSITY
  •  Molecular biology of form cell generation in atherosclerosisPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Study on the role of arterial retention of lipoprotein and its regulators in the development of atheroselerosis

    • Principal Investigator
      ISHIBASHI Syun
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Development of animal models for atherosclerosis and obesity, and molecular mechanism of the common pathwayPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  動脈硬化形成における小腸由来リポタンパクに関する発生工学的研究

    • Principal Investigator
      石橋 俊
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Gene targeting study on mechanisms for cholesterol accumulation in the arteryPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Development of basic techniques for the liver-directed gene therapy

    • Principal Investigator
      ISHIBASHI Shun
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  アルツハイマー病発症におけるアポEの意義Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  アポリポ蛋白Eのトランスジェニックマウスの開発と応用Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Establishment of animal models for atheroscherosis and gene therapyPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  血小板由来血管内細胞増殖因子の生理的意義の解析

    • Principal Investigator
      豊島 秀男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  LPLおよびLCAT遺伝子変異に基く高脂血症,低HDL血症の発症メカニズムPrincipal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  動脈硬化症の分子生物学的解析と予防・抑制対策に関する総合的研究

    • Principal Investigator
      北 徹
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  血小板由来血管内皮細胞増殖因子の生理的意義の解析

    • Principal Investigator
      TOYOSHIMA Hideo
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  粥状動脈硬化症の成因におけるアポEの意義Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  コレステロ-ル代謝におけるアポEレセプタ-の機能Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Therapeutic trial of atherosclerosis by M-CSFPrincipal Investigator

    • Principal Investigator
      YAMADA Nobuhiro
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  糖尿病性神経症におけるアポEの役割Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Study for the pathogenesis of atherosclerosis.

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  アポB100を含むリポ蛋白の代謝とアポEの役割Principal Investigator

    • Principal Investigator
      山田 信博
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Basic Research and Clinical Application of Hematopoietic Growth Factors

    • Principal Investigator
      YAMAJI Tohru, TAKAKU Fumimaro (高久 史麿)
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Faculty of Medicine, University of Tokyo

All 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

  • [Book] 糖尿病診療に必要な知識1 2型糖尿病の血管合併症-JDCSの成果.糖尿病学の進歩2011 第45集2011

    • Author(s)
      曽根博仁, 片山茂裕, 山下英俊, 赤沼安夫, 山田信博
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Book] 大血管症.糖尿病の栄養指導2009

    • Author(s)
      曽根博仁, 山田信博, 赤沼安
    • Publisher
      日本糖尿病学会編診断と治療社
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] the Japanese Elderly Intervention Trial Research Group. Non-high-density lipoprotein cholesterol : An important predictor of stroke and diabetes-related mortality in Japanese elderly diabetic patients2012

    • Author(s)
      Araki A, Iimuro S, Sakurai T, Umegaki H, Iijima K, Nakano H, Oba K, Yokono K, Sone H, Yamada N, Ako J, Kozaki K, Miura H, Kashiwagi A, Kikkawa R, Yoshimura Y, NakanoT, Ohashi Y, Ito H
    • Journal Title

      Geriatr Gerontol Int

      Volume: 12 Pages: 18-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] High normal HbA1c levels were associated with impaired insulin secretion without escalating insulin resistance in Japanese individuals : The Toranomon Hospital Health Management Center Study 8 (TOPICS 8)2012

    • Author(s)
      Heianza Y, Arase Y, Fujihara K, Tsuji H, Saito H, Hsieh SD, Kodama S, Shimano1 H, Yamada N, Hara S, Sone H
    • Journal Title

      Diabet Med

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Longitudinal trajectories of HbA1c and fasting plasma glucose levels during the development of type 2 diabetes : TOPICS 72012

    • Author(s)
      Heianza Y, Arase Y, Fujihara K, Hsieh SD, SaitoK, Tsuji H, Kodama S, Yahagi N, Shimano H, Yamada N, Hara S, Sone H
    • Journal Title

      Diabetes Care

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Management of Type IIb Dyslipidemia2012

    • Author(s)
      Arai H, Ishibashi S, Bujo H, Hayashi T, Yokoyama S, Oikawa S, Kobayashi J, Shirai K, Ota T, Yamashita S, Gotoda T, Harada-Shiba M, Sone H, Eto M, Suzuki H, Yamada N.
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 2 Pages: 105-114

    • DOI

      10.5551/jat.10447

    • NAID

      130004444573

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-20406004, KAKENHI-PROJECT-21590762, KAKENHI-PROJECT-22591004
  • [Journal Article] Effect of Web-based Lifestyle Modification on Weight Control : A Meta-analysis2012

    • Author(s)
      Kodama S, Saito K, Tanaka S, Horikawa C, Fujiwara K, Hirasawa R, Yachi Y, Iida KT, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      Int J Obes

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Longitudinal trajectories of HbAlc and fasting plasma glucose levels during the development of type 2 diabetes : the Toranomon Hospital Health Management Center Study 7 (TOPICS 7)2012

    • Author(s)
      Heianza Y, Arase Y, Fujihara K, Hsieh SD, Saito K, Tsuji H, Kodama S, Yahagi N, Shimano H, Yamada N, Hara S, Sone H.
    • Journal Title

      Diabetes Care

      Volume: 35 Issue: 5 Pages: 1050-1052

    • DOI

      10.2337/dc11-1793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J00046, KAKENHI-PROJECT-20300227, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-24300233
  • [Journal Article] Background to Discuss Guidelines for Control of Plasma HDL-Cholesterol in Japan*2012

    • Author(s)
      Yokoyama S, Yamashita S, Ishibashi S, Sone H, Oikawa S, Shirai K, Ohta T, Bujo H, Kobayashi J, Arai H, Harada-Shiba M, Eto M, Hayashi T, Gotoda T, Suzuki H, Yamada N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 3 Pages: 207-212

    • DOI

      10.5551/jat.11452

    • NAID

      130004444591

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-20406004, KAKENHI-PROJECT-21590762, KAKENHI-PROJECT-22591004, KAKENHI-PROJECT-24614018
  • [Journal Article] Comparison of Various Lipid Variables as Predictors of Coronary Heart Disease in Japanese Men and Women with Type 2 Diabetes. Subanalysis of the Japan Diabetes Complications Study (JDCS)2012

    • Author(s)
      Sone H, Tanaka S, Tanaka S, Iimuro S, Ishibashi S, Oikawa S, Shimano H, Katayama S, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      Diabetes Care

      Volume: (in press) Issue: 5 Pages: 1150-1157

    • DOI

      10.2337/dc11-1412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-23390185, KAKENHI-PROJECT-24300233, KAKENHI-PROJECT-24659346
  • [Journal Article] Impact of introducing HbAlc into the diagnostic criteria on prevalence and cardiovascular risk profiles of individuals with newly diagnosed diabetes in Japan : the Toranomon Hospital Health Management Center Study 2 (TOPICS 2)2012

    • Author(s)
      Heianza Y, Hara S, Arase y Saito K, Tsuji H, Kodama S, Hsieh SD, Mori Y, Okubo M, Yamada N, Kosaka K, Sone H
    • Journal Title

      Diabetes research and clinical practice

      Volume: 95 Issue: 2 Pages: 283-290

    • DOI

      10.1016/j.diabres.2011.10.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J00046, KAKENHI-PROJECT-20300227
  • [Journal Article] Fasting and Post-Challenge Glucose as Quantitative Cardiovascular Risk Factors: A Meta-Analysis2012

    • Author(s)
      Fujiwara K, Hirasawa R, Yachi Y, Sone Y, Tada Iida K, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 4 Pages: 385-396

    • DOI

      10.5551/jat.10975

    • NAID

      130004444600

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Diagnosis and Management of Type I and Type V Hyperlipoproteinemia2012

    • Author(s)
      Gotoda T, Shirai K, Ohta T, Kobayashi J, Yokoyama S, Oikawa S, Bujo H, Ishibashi S, Arai H, Ya mashita S, Harada-Shiba M, Eto M, Hayashi T, Sone H, Suzuki H, Yamada N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 19 Issue: 1 Pages: 1-12

    • DOI

      10.5551/jat.10702

    • NAID

      130004721898

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-20406004, KAKENHI-PROJECT-21590762, KAKENHI-PROJECT-22591004
  • [Journal Article] Low Serum Potassium Levels and Risk of Type 2 Diabetes : Toranomon Hospital Health Management Center Study 1 (TOPICS 1)2011

    • Author(s)
      Heianza Y, Hara S, Arase Y, Saito K, Totsuka K, Tsuji H, Kodama S, Hsieh SD, Yamada N, Kosaka K, Sone H
    • Journal Title

      Diabetologia

      Volume: 54 Issue: 4 Pages: 762-766

    • DOI

      10.1007/s00125-010-2029-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] on behalf of the Japan Diabetes Complications Study Group. Incidence and progression of diabetic retinopathy in Japanese adults with type 2 diabetes : 8 year follow-up study of the Japan Diabetes Complications Study (JDCS)2011

    • Author(s)
      Kawasaki R, Tanaka S, Tanaka S, Yamamoto T, Sone H, Ohashi Y, Akanuma Y, Yamada N, Yama shita Y
    • Journal Title

      Diabetologia

      Volume: 54 Issue: 9 Pages: 2288-2294

    • DOI

      10.1007/s00125-011-2199-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Alcohol Consumption and Risk of Atrial Fibrillation : A Meta-analysis2011

    • Author(s)
      Kodama S, Saito K, Tanaka S, Horikawa C, Saito A, Heianza Y, Anasako Y, Nishigaki Y, Yachi Y, Iida KT, Ohashi Y, Yamada N, Sone H
    • Journal Title

      J Am Coll Cardiol

      Volume: 57 Issue: 4 Pages: 427-36

    • DOI

      10.1016/j.jacc.2010.08.641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Serum Level of Triglycerides is a Potent Risk Factor Comparable to LDL Cholesterol for Coronary Heart Disease in Japanese Patients with Type 2 Diabetes. Subanalysis of the Japan Diabetes Complications Study (JDCS)2011

    • Author(s)
      Sone H, Tanaka S, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      J Clin Endocrinol Metab

      Volume: 96 Issue: 11 Pages: 3448-56

    • DOI

      10.1210/jc.2011-0622

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Alcohol Consumption and Risk of Atrial Fibrillation : A Meta-analysis.2011

    • Author(s)
      Kodama S, Saito K, Tanaka S, Horikawa C, Saito A, Heianza Y, Anasako Y, Nishigaki Y, Yachi Y, Iida KT, Ohashi Y, Yamada N, Sone H.
    • Journal Title

      J Am Coll Cardiol 57

      Pages: 427-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] 血清カリウム低値と2型糖尿病発症リスク2011

    • Author(s)
      平安座依子, 原茂子, 荒瀬康司, 山田信博, 曽根博仁
    • Journal Title

      肥満と糖尿病

      Volume: 10 Pages: 284-287

    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Contribution of glimepiride to basal-prandial insulin therapy in patients with type 2 diabetes2011

    • Author(s)
      Yokoyama H, Sone H, Yamada D, Honjo J, Haneda M.
    • Journal Title

      Diabet Res Clin Pract

      Volume: 91 Issue: 2 Pages: 148-53

    • DOI

      10.1016/j.diabres.2010.10.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] 日本人糖尿病患者の実態-JDCS2011

    • Author(s)
      曽根博仁, 片山茂裕, 山下英俊, 赤沼安夫, 山田信博
    • Journal Title

      診断と治療

      Volume: 99 Pages: 1805-1812

    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] HbA1c 5.7-6.4% and impaired fasting plasma glucose for diagnosis of prediabetes and risk of progeression to diabetes in Japan (TOPICS 3) : a longitudinal cohort study2011

    • Author(s)
      Heianza Y, Hara S, Arase Y, Saito K, Fujiwara K, Tsuji H, Kodama S, Hsieh SD, Mori Y, Shimano H, Yamada N, Kosaka K, Sone H
    • Journal Title

      Lancet

      Volume: 378 Issue: 9786 Pages: 147-55

    • DOI

      10.1016/s0140-6736(11)60472-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Contribution of glimepiride to basal-prandial insulin therapy in patients with type 2 diabetes.2011

    • Author(s)
      Yokoyama H, Sone H, Yamada D, Honjo J, Haneda M.
    • Journal Title

      Diabetes Res Clin Pract. in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Low Serum Potassium Levels and Risk of Type 2 Diabetes : Toranomon Hospital Health Management Center Study 1 (TOPICS 1)2011

    • Author(s)
      Heianza Y, Hara S, Arase Y, Saito K, Totsuka K, Tsuji H, Kodama S, Hsieh SD, Yamada N, Kosaka K, Sone H.
    • Journal Title

      Diabetologia in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Risks for glomerular filtration rate decline in association with progression of albuminuria in type 2 diabetes2011

    • Author(s)
      Yokoyama H, Kanno S, Takahashi S, Yamada D, Honjo J, Saito K, Sone H, Haneda M.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 26 Issue: 9 Pages: 2924-30

    • DOI

      10.1093/ndt/gfq774

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] 日本人2型糖尿病患者における大血管合併症の疫学2011

    • Author(s)
      曽根博仁, 山田信博, 赤沼安夫
    • Journal Title

      糖尿病

      Volume: 54 Pages: 2-5

    • NAID

      10028116475

    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] — Interrelations with Arterial Thickness and Stiffness2011

    • Author(s)
      Yokoyama H, Sone H, Saito K, Yamada D, Honjo J, Haneda M
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 18 Issue: 9 Pages: 744-752

    • DOI

      10.5551/jat.7526

    • NAID

      130004845387

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Skipping Breakfast and Prevalence of Overweight and Obesity in Asian and Pacific Regions : A Meta-analysis2011

    • Author(s)
      Horikawa C, Kodama S, Yachi Y, Heianza Y, Hira sawa R, Ibe Y, Saito K, Shimano H, Yamada N, Sone H
    • Journal Title

      Prev Med

      Volume: 53 Issue: 4-5 Pages: 260-7

    • DOI

      10.1016/j.ypmed.2011.08.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] 糖尿病と動脈硬化-疫学的知見2011

    • Author(s)
      曽根博仁, 山田信博
    • Journal Title

      動脈硬化予防

      Volume: 10 Pages: 5-13

    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Low Transition Rate from Normo and Low Microalbuminuria to Proteinuria in Japanese Type 2 Diabetics : the Japan Diabetes Complications Study (JDCS)2011

    • Author(s)
      Katayama S, Moriya T, Tanaka S, Tanaka S, Yajima Y, Sone H, Iimuro S, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      Diabetologia

      Volume: 54 Issue: 5 Pages: 1025-31

    • DOI

      10.1007/s00125-010-2025-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Self-reported fast eating is a potent predictor of development of impaired glucose tolerance in Japanese men and women : Tsukuba Medical Center Study2011

    • Author(s)
      Totsuka K, Maeno T, Saito K, Kodama S, Asumi M, Yachi Y, Hiranuma Y, Shimano H, Yamada N, Ono Y, Naito T, Sone H
    • Journal Title

      Diabet Res Clin Prac

      Volume: 94 Issue: 3 Pages: e72-e74

    • DOI

      10.1016/j.diabres.2011.08.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Macrophage Elovl6 deficiency ameliorates foam cell formation and reduces atherosclerosis in low-density lipoprotein receptor-deficient mice2011

    • Author(s)
      Saito R, Matsuzaka T, Karasawa T, Sekiya M, Okada N, Igarashi M, Matsumori R, Ishii K, Nakagawa N, Kobayashi K, Yatoh S, Takahashi A, Sone H, Suzuki H, Yahagi N, Yamada N Shimano H
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 31 Issue: 9 Pages: 1973-9

    • DOI

      10.1161/atvbaha.110.221663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227, KAKENHI-PROJECT-21591123, KAKENHI-PLANNED-23116006, KAKENHI-PROJECT-23659473
  • [Journal Article] Long-term lifestyle intervention lowers incidence of stroke in Japanese patients with type 2 diabetes : a nationwide multicenter randomised controlled trial. (the Japan Diabetes Complications Study)2010

    • Author(s)
      Sone H, Tanaka S, Iimuro S, Tanaka S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Yamashita H, Ito H, Yoshimura Y, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      Diabetologia

      Volume: 53 Issue: 3 Pages: 419-428

    • DOI

      10.1007/s00125-009-1622-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit2010

    • Author(s)
      Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga JI, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H.
    • Journal Title

      J Biol Chem 285

      Pages: 11681-11691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] A Hierarchical Regression Model for Dietary Data Adjusting for Covariates Measurement Error by Regression Calibration : An Application to a Large Prospective Study for Diabetic Complications2010

    • Author(s)
      Taguri T, Matsuyama Y, Ohashi Y, Sone H, Yoshimura Y, Yamada N
    • Journal Title

      Jpn J Biometrics

      Volume: 31 Pages: 49-61

    • NAID

      10027840240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] The liver-enriched transcription factor CREBH is nutritionally regulated and activated by fatty acids and PPARalpha2010

    • Author(s)
      Danno H, Ishii KA, Nakagawa Y, Mikami M, Yamamoto T, Yabe S, Furusawa M, Kumadaki S, Watanabe K, Shimizu H, Matsuzaka T, Kobayashi K, Takahashi A, Yatoh S, Suzuki H, Yamada N, Shimano H
    • Journal Title

      Biochem Biophys Res Commun 391

      Pages: 1222-1227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Long-term lifestyle intervention lowers incidenceof stroke in Japanese patients with type 2 diabetes : a nationwide multicenter randomised controlled trial. (the Japan Diabetes Complications Study).2010

    • Author(s)
      Sone H, Tanaka S, Iimuro S, Tanaka S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Yamashita H, Ito H, Yoshimura Y, Ohashi Y, Akanuma Y, Yamada N.
    • Journal Title

      Diabetologia 53

      Pages: 419-428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Hormone-sensitive lipase deficiency suppresses insulin secretion from pancreatic islets of Lep(ob)(/)(ob)mice2009

    • Author(s)
      Sekiya M, Yahagi N, Tamura Y, Okazaki H, Igarashi M, Ohta K, Takanashi M, Kumagai M, Takase S, Nishi M, Takeuchi Y, Izumida Y, Kubota M, Ohashi K, Iizuka Y, Yagyu H, Gotoda T, Nagai R, Shimano H, Yamada N, Kadowaki T, Ishibashi S, Osuga JI.
    • Journal Title

      Biochem Biophys Res Commun 387

      Pages: 511-515

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Influence of fat and carbohydrate proportions on the metabolic profile in patients with type 2 diabetes : a meta-analysis2009

    • Author(s)
      Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Sato M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      Diabetes Care 32

      Pages: 959-965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women2009

    • Author(s)
      Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      JAMA

      Volume: 301 Issue: 19 Pages: 2024-2035

    • DOI

      10.1001/jama.2009.681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women : a meta-analysis2009

    • Author(s)
      Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      JAMA 301

      Pages: 2024-2035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Influence of Fat and Carbohydrate Proportions on the Metabolic Profile in Patients with Type 2 Diabetes : A Meta-analysis2009

    • Author(s)
      Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Sato M, Sugawara A, Totsuka K, Shimano H, Ohashi Y, Yamada N, Sone H
    • Journal Title

      Diabetes Care

      Volume: 32 Issue: 5 Pages: 959-965

    • DOI

      10.2337/dc08-1716

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] The up-regulation of microRNA-335 is associated with lipid metabolism in liver and white adipose tissue of genetically obese mice2009

    • Author(s)
      Nakanishi N, Nakagawa Y, Tokushige N, Aoki N, Matsuzaka T, Ishii K, Yahagi N, Kobayashi K, Yatoh S, Takahashi A, Suzuki H, Urayama O, Yamada N, Shimano H
    • Journal Title

      Biochem Biophys Res Commun 385

      Pages: 492-496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Components of Metabolic Syndrome and their Combinations as Predictors of Cardiovascular Disease in Japanese Patients with Type 2 Diabetes. Implications for Improved Definition. Analysis from Japan Diabetes Complications Study (JDCS)2009

    • Author(s)
      Sone H, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Oikawa S, Ishibashi S, Katayama S, Ito H, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 16 Issue: 4 Pages: 380-387

    • DOI

      10.5551/jat.No117

    • NAID

      130004444297

    • ISSN
      1340-3478, 1880-3873
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Low HDL-cholesterol is associated with the risk of stroke in elderly diabetic individuals : Changes in the risk for atherosclerotic diseases at various ages2009

    • Author(s)
      Hayashi T, Kawashima S, Itoh H, Yamada N, Sone H, Watanabe H, Hattori Y, Ohrui T, Yokote K, Nomura H, Umegaki H, Iguchi A
    • Journal Title

      Diabetes Care

      Volume: 32 Issue: 7 Pages: 1221-1223

    • DOI

      10.2337/dc08-1677

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Determinants of decline in glomerular filtration rate in nonproteinuric subjects with or without diabetes and hypertension2009

    • Author(s)
      Yokoyama H, Kanno S, Takahashi S, Yamada D, Itoh H, Saito K, Sone H, Haneda M
    • Journal Title

      Clin J Am Soc Nephrol

      Volume: 4 Issue: 9 Pages: 1432-1440

    • DOI

      10.2215/cjn.06511208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] Wais tcircumference as a cardiovascular and metabolic risk in Japanese patients with type 2 diabetes2009

    • Author(s)
      Sone H, Tanaka S, Iimuro S, Oida K, Yamasaki Y, Ishibashi S, Oikawa S, Katayama S, Ito H, Ohashi Y, Akanuma Y, Yamada N
    • Journal Title

      Obesity

      Volume: 17 Issue: 3 Pages: 585-92

    • DOI

      10.1038/oby.2008.481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Journal Article] SPARC is a major secretory gene expressed and involved in the development of proliferative diabetic retinopathy2009

    • Author(s)
      Watanabe K, Okamoto F, Yokoo T, Tada Iida K, Suzuki H, Shimano H, Oshika T, Yamada N, Toyoshima H
    • Journal Title

      J Atheroscler Thromb 16

      Pages: 69-76

    • NAID

      10025764920

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20052006
  • [Journal Article] Crucial role of a long-chain fatty acid elongase, Elov16, in obesity-induced insulin resistance.2007

    • Author(s)
      Matsuzaka T, Yamada N, et. al.
    • Journal Title

      Nat Med 13

      Pages: 1193-1202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] SREBP-1-endependent regulation of lipogenic gene expression in adipocytes.2007

    • Author(s)
      Sekiya M, Yamada N, Shimano H, et. al.
    • Journal Title

      J Lipid Res 48(7)

      Pages: 1581-1591

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Protein Kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.2007

    • Author(s)
      Yamamoto T, Shimano H, Takahashi A, Yamada N, et. al.
    • Journal Title

      J Biol Chem 282(16)

      Pages: 11687-11695

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Risk imparted bu various parameters of smoking in Japanese men with type 2 deabetes on their development of microalbuminuria : analysis from the Tsukuba kawai Diabetes Registry.2007

    • Author(s)
      Saito K, Shimano H, Yamada N, et. al.
    • Journal Title

      Diabetes Care 30(5)

      Pages: 1286-1288

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Polymorphisms of apolipoprotein e and methylenetetrahydrofolate reductase in the Japanses population.2007

    • Author(s)
      Arai H, Yamada N, et. al.
    • Journal Title

      J Atheroscler Thromb 14(4)

      Pages: 167-171

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.2007

    • Author(s)
      Taleuchi Y, Yamada N, Shimano H, et. al.
    • Journal Title

      Biochem Biophys Res Commun 363(2)

      Pages: 329-335

    • NAID

      120007139072

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Protein kinase A suppresses sterol regulatory element-binding protein-1Cexpression via phosphorylation of liver X receptor in the liver.2007

    • Author(s)
      Yamamoto T, Yamada N, et. al.
    • Journal Title

      J Biol Chem 282

      Pages: 11687-11695

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Cross-sectional association between BMI, glycemic control and energy intake in Japanese patients with type 2 deabetes. Analysis from the Japan Diabetes Complications Study.2007

    • Author(s)
      Sone H, Yamada N, Japan Diabetes Complications Study(JDCS)Group, et. al.
    • Journal Title

      Diabetes Res Clin Pract 77(Supp l)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Identification of ISG 12b as a putative interferon-inducible adipocytokine which is highly expressed in white asipose tissue2007

    • Author(s)
      Ohgaki S, Shimano H, Yamada N, et. al.
    • Journal Title

      J Atherpscler Thromb 14(4)

      Pages: 179-184

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Effect of aerobic exercise training on serum levels of high-density lipoprotein cholesterol: a meta-analysis.2007

    • Author(s)
      Kodama S, Yamada N, et. al.
    • Journal Title

      Arch Intern Med 167

      Pages: 999-1008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Effect of aerobic exercese training on serum levels of high-density lipoprotein cholesterol : a meta-analysis.2007

    • Author(s)
      Kodama S, Shimano H, Yamada N, et. al.
    • Journal Title

      Arch Intern Med 167(10)

      Pages: 999-1008

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Even low-intensity and low-volume exercise training may improve insulin resistance in the elderly.2007

    • Author(s)
      Kodama S, Takahashi A, Shimano H, Yamada N, et. al.
    • Journal Title

      Intern Med 46(14)

      Pages: 1071-1077

    • NAID

      130000076125

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Effects of pioglitazone hydrochloride on Japanese patients with type diabetes mellitus.2007

    • Author(s)
      Teramoto T, Yamada N, et. al.
    • Journal Title

      J Atheroscler Thromb 14(2)

      Pages: 86-93

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Crucial role of a long-chain fatty acid elongase, Elov16, in obesity-induced insulin resistance.2007

    • Author(s)
      Matsuzaka T, Shimano H, Takahashi A, Yamada N, et. al.
    • Journal Title

      Nat Med 13(10)

      Pages: 1193-1202

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Effect of rosuvastatin 5-20 mg on triglycerides and other lipid parameters in Japanese patients with hypertriglyceridemia2007

    • Author(s)
      Saito Y, Yamada N, et. al.
    • Journal Title

      Atherosclerosis 194(2)

      Pages: 505-511

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction.2007

    • Author(s)
      Shimano H, Takahashi A, Yamada N, et. al.
    • Journal Title

      Doabetes Obe Metab 9(Suppl 2)

      Pages: 133-139

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Granuphilin is avtivated bu SREBP-1c and involved in inpaired insulin secretion in diabetic mice.2006

    • Author(s)
      Kato T, Shimano H, Takahashi A, Yamada N, et. al.
    • Journal Title

      Cell Metab 4(2)

      Pages: 143-154

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] TFE 3 transcriptionally cativates hepatic IRS-2, participates in insulin signaling and ameliorates diabetes.2006

    • Author(s)
      Nakagawa Y, Shimano H, Takahashi A, Yamada N, et. al.
    • Journal Title

      Nat Med 12(1)

      Pages: 107-113

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Outcome of one-year of specialist care of patients with type 2 diabetes : a multi-center prospevtive survey(JDDM 2).2006

    • Author(s)
      Sone H, Yamada N, et. al.
    • Journal Title

      Intern Med 45(9)

      Pages: 589-597

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] The effect of exercise training on adiponectin receptor expression in KKAy obese/diabetic mice.2006

    • Author(s)
      Huang Hu, Kaoruko Tada Iida, Hirohito Sone, Tomotaka Yokoo, Nobuhiro Yamada, Ryuichi Ajisaka.
    • Journal Title

      Journal of Endocrinology 189(3)

      Pages: 643-53

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17500414
  • [Journal Article] Regulation of hepatic cholesterol synthesis by o novel protein(SPF) that accelerates cholesterol biosynthesis.2006

    • Author(s)
      Shibata N, Shimano H, Yamada N, et. al.
    • Journal Title

      FASEB J. 20(14)

      Pages: 2642-2644

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] The new worldwide definition of metabolic syndrome is not a better diagnostic predictor of cardiovascular disease in Japanese diabetic patients than the existing definitions : additional analysis from the Japan Diabetes Complications Study.2006

    • Author(s)
      Sone H, Yamada N, Japan Diabetes Complications Study(JDCS)Group, et. al.
    • Journal Title

      Diabetes Care 29(1)

      Pages: 145-147

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] The effect of exercise training on adiponectin receptor expression in KKAy obese/diabetic mice.2006

    • Author(s)
      Huang H, Iida KT, Sone H, Yokoo T, Yamada N, Ajisaka R
    • Journal Title

      Journal of Endocrinology 189 (3)

      Pages: 643-653

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17500414
  • [Journal Article] The effect of exercise training on adiponectin receptor expression in KKAy obese/diabetic mice.2006

    • Author(s)
      Huang H, Yamada N, et. al.
    • Journal Title

      J Endpcronol 189(3)

      Pages: 643-653

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Distinct Effects of Pravastain, Atorvastain, and Simvastain on Insulin Secretion from a beta-cell Line, MIN6 Cells.2006

    • Author(s)
      Ishikawa M, Takahashi A, Yamada N, Shimano H, et. al.
    • Journal Title

      J Altheroscler Thromb 13(6)

      Pages: 329-335

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol : a potential role in asipocyte liplysis.2006

    • Author(s)
      Okazaki H, Shimano H, Yamada N, et. al.
    • Journal Title

      Diabetes 55(7)

      Pages: 2091-2097

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390268
  • [Journal Article] Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed transgenic rabbits.2005

    • Author(s)
      Ichikawa T, Liang J, Kitajima S, Koike T, Wang X, Sun H, Morimoto M, Shikama H, Watanabe T, Yamada N, Fan J.
    • Journal Title

      Atherosclerosis. 179

      Pages: 87-95

    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells.2005

    • Author(s)
      Takahashi A, Yamada N, et al.
    • Journal Title

      Diabetes 54

      Pages: 492-499

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] High mobility group protein-B1 (HMGB1) interacts with sterol regulatory element-binding proteins (SREBPs) to enhance their DNA binding.2005

    • Author(s)
      Najima Y, Yamada N, et al.
    • Journal Title

      J Biol Chem 280(30)

      Pages: 27523-27532

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits.2005

    • Author(s)
      Ichikawa, T., Liang, J., Kitajima, S., Koike, T., Wang, X., Sun, H., Morimoto, M., Shikama, H., Watanabe, T., Yamada, N., Fan, J.
    • Journal Title

      Atherosclerosis 179

      Pages: 87-95

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Sterol Regulatory Element-binding Proteins Activate Insulin Gene Promoter Directly and Indirectly through Synergy with BETA2/E47.2005

    • Author(s)
      Amemiya-Kudo M, Yamada N, et al.
    • Journal Title

      J Biol Chem 280(41)

      Pages: 34577-34589

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] High lipoprotein lipase activity increases insulin sensitivity in transgenic rabbits.2005

    • Author(s)
      Liu, E., Kitajima, S., Higaki, Y., Morimoto, M., Sun, H., Watanabe, T., Yamada, N., Fan, J.
    • Journal Title

      Metabolism Clinical and Experimental 54

      Pages: 132-138

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed transgenic rabbits2005

    • Author(s)
      Ichikawa T, Liang J, Kitajima S, Koike T, Wang X, Sun H, Morimoto M, Shikama H, Watanabe T, Yamada N, Fan J
    • Journal Title

      Atherosclerosis 179

      Pages: 87-95

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Lipid synthetic transcription factor SREBP-1a activates p21 WAF1/CIP1, a universal cyclin-dependent kinase inhibitor.2005

    • Author(s)
      Inoue N, Yamada N, et al.
    • Journal Title

      Mol Cell Bid 25(20)

      Pages: 8938-8947

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] High lipoprotein lipase increases insulin sensitivity in transgenic rabbits2005

    • Author(s)
      Liu E, Kitajima S, Morimoto M, Sun H, Watanabe T, Yamada N, Fan J
    • Journal Title

      Metabolism 54

      Pages: 132-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Scavenger receptor expressed by endothelial cells I (SREC-I) mediates the uptake of acetylated low density lipoproteins by macrophages stimulated with lipopolysaccharide.2004

    • Author(s)
      Tamura Y, Yamada N, et al.
    • Journal Title

      J Biol Chem. 279(30)

      Pages: 30938-30944

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] Overexpression of lipoprotein lipase in transgenic Watanabe heritable hyperlipidemic rabbits improves hyperlipidemia and obesity2004

    • Author(s)
      Koike T, Liang J, Wang X, Ichikawa T, Shiomi M, Liu G, Sun H, Kitajima S, Morimoto M, Watanabe T, Yamada N, Fan J
    • Journal Title

      J Biol Chem 279

      Pages: 7521-7529

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis.2004

    • Author(s)
      Ichikawa, T., Kitajima, S., Liang, J., Koike, T., Wang, X., Sun, H., Okazaki, M., Morimoto, M., Shikama, H., Watanabe, T., Yamada, N., Fan, J.
    • Journal Title

      Laboratory Investigation 84

      Pages: 715-726

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis2004

    • Author(s)
      Ichikawa T, Kitajima S, Liang J, Koike T, Wang X, Sun H, Okazaki M, Morimoto M, Shikama H, Watanabe T, Yamada N, Fan J
    • Journal Title

      Lab Invest 84

      Pages: 715-726

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Overexpression of lipoprotein lipase improves insulin resistance induced by a high-fat diet in transgenic rabbits.2004

    • Author(s)
      Kitajima, S., Morimoto, M., Liu, E., Koike, T., Higaki, Y., Taura, Y., Mamba, K., Itamoto, K., Watanabe, T., Tsutsumi, K., Yamada, N., Fan, J.
    • Journal Title

      Diabetologia 47

      Pages: 1202-1209

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] SREBPs suppress IRS-2-mediated insulin signalling in the liver.2004

    • Author(s)
      Ide T, Yamada N, et al.
    • Journal Title

      Nat Cell Biol 6(4)

      Pages: 351-357

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390260
  • [Journal Article] Overexpression of Lipoprotein Lipase in Transgenic Watanabe Heritable Hyperlipidemic Rabbits Improves Hyperlipidemia and Obesity.2004

    • Author(s)
      Koike, T., Liang, J., Wang, X., Ichikawa, T., Shiomi, M., Liu, G., Sun, H., Kitajima, S., Morimoto, M., Watanabe, T., Yamada, N., Fan, J.
    • Journal Title

      J Biol Chem 279・9

      Pages: 7521-7529

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Journal Article] Overexpression of lipoprotein lipase improves insulin resistance induced by a high-fat diet in transgenic rabbits2004

    • Author(s)
      Kitajima S, Morimoto M, Liu E, Koike T, Higaki Y, Taura Y, Mamba K, Itamoto K Watanabe T, Tsutsumi K, Yamada N, Fan J
    • Journal Title

      Diabetologia 47

      Pages: 1202-1209

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390089
  • [Presentation] 2型糖尿病発症予測に最適なHbA1cと空腹時血糖値の閾値の組み合わせの検討:TOPICS2012

    • Author(s)
      平安座依子, 原茂子, 謝勲東, 齋藤和美, 辻裕之, 菅原歩美, 齋藤あき, 児玉暁, 荒瀬康司, 山田信博, 曽根博仁
    • Organizer
      第46回日本成人病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-15
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] HbA1cを導入した新しい2型糖尿病予測スコアリングシステムの開発2012

    • Author(s)
      平安座依子, 謝勲東, 原茂子, 辻裕之, 藤原和哉, 堀川千嘉, 谷内洋子, 児玉暁, 山田信博, 荒瀬康司, 曽根博仁
    • Organizer
      第46回日本成人病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-14
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 2型糖尿病発症前のHbA1c値と空腹時血糖値の変化に関する大規模縦断的検討2012

    • Author(s)
      平安座依子, 荒瀬康司, 辻裕之, 齋藤和美, 藤原和哉, 謝勲東, 児玉暁, 山田信博, 原茂子, 曽根博仁
    • Organizer
      第46回日本成人病学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-14
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] HbA1cの変動が微量アルブミン尿発症に及ぼす影響の検討2012

    • Author(s)
      菅原歩美, 川井紘一, 齋藤和美, 本橋しのぶ, 島野仁, 山田信博, 曽根博仁
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-26
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 震災時の精神的ストレスが血糖に与える影響2012

    • Author(s)
      藤原和哉, 宜保英彦, 小林和人, 高橋昭光, 矢藤繁, 鈴木浩明, 島野仁, 山田信博, 曽根博仁
    • Organizer
      第20回臨床内分泌代謝:Update
    • Place of Presentation
      浜松
    • Year and Date
      2012-01-27
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 異なる空腹時血糖値異常とHbA1c高値の判定基準を用いた2型糖尿病予測スクリーニング精度の比較:TOPICS2012

    • Author(s)
      平安座依子, 原茂子, 謝勲東, 児玉暁, 辻裕之, 藤原和哉, 由澤咲子, 伊部陽子, 齋藤和美, 山田信博, 荒瀬康司, 曽根博仁
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-26
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 抗GAD抗体が陽性であった高齢発症の激症1型糖尿病の1例2012

    • Author(s)
      村山友樹, 藤原和哉, 宜保英彦, 尾本美代子, 小林和人, 高橋昭光, 矢藤繁, 鈴木浩明, 島野仁, 山田信博, 曽根博仁
    • Organizer
      第85回日本内分泌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-04-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 2型糖尿病発症10年間のHbA1c値の変化:TOPICS2012

    • Author(s)
      平安座依子, 荒瀬康司, 辻裕之, 齋藤和美, 藤原和哉, 謝勲東, 児玉暁, 山田信博, 原茂子, 曽根博仁
    • Organizer
      第22回日本疫学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-26
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Association between the severity of diabetic retinopathy and the incidence of the macrovascular diseases onset : 8-year follow-up study of the Japan Diabetes Complications Study (JDCS)2011

    • Author(s)
      Abe S, Tanaka S, Yamamoto T, Ohashi Y, Sone H, Yamada N, Yamashita H
    • Organizer
      4th Annual Meeting of the D&CVD EASD Study Group
    • Place of Presentation
      Munich, Germany
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] HbA1cと空腹時血糖値による糖尿病型の判定基準と臨床指標の比較(TOPICS)2011

    • Author(s)
      平安座依子, 原茂子, 齋藤和美, 藤原和哉, 辻裕之, 児玉暁, 謝勲東, 島野仁, 荒瀬康司, 山田信博, 小坂樹徳, 曽根博仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 生涯最大体重や20歳時の体重はその後の未診断糖尿病や前糖尿病状態の発症と関連する(TOPICS)2011

    • Author(s)
      平安座依子, 原茂子, 齋藤和美, 児玉暁, 飯田薫子, 赤松利恵, 鈴木恵美子, 近藤和雄, 荒瀬康司, 山田信博, 小坂樹徳、 曽根博仁
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 経口ブドウ糖負荷前・負荷後血糖の心血管疾患リスクの量的関係の解析(メタアナリシス)2011

    • Author(s)
      齋藤和美, 児玉暁, 堀川千嘉, 伊部陽子, 平澤玲子, 谷内洋子, 菅原歩美, 小林和人, 高橋昭光, 島野仁, 山田信博, 曽根博仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] IMTの規定因子とIMT変化へ影響する介入因子の検討2011

    • Author(s)
      猪苅冬樹, 奥田昌恵, 高橋直穂, 菅野咲子, 本庄潤, 山田大志郎, 曽根博仁, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Impact of serum lipid level on number of vulnerable coronary plaque (VP) detected by CT angiography (CTA) in asymptomatic patients with type 2 diabetes2011

    • Author(s)
      藤原和哉, 鈴木浩明, 佐藤明, 大崎芳典, 尾本美代子, 豊崎晶子, 平安座依子, 児玉暁, 齋藤和美, 小林和人, 高橋昭光, 矢藤繁, 山田信博, 曽根博仁, 野仁
    • Organizer
      第43回日本動脈硬化学会総会・学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-07-16
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Screening using various cutoffs of HbA1c and impaired fasting plasma glucose for predicting future diabetes : The Toranomon hospital health management center study2011

    • Author(s)
      Horikawa C, Heianza Y, Hara S, Arase Y, Saito K, Fujiwara K, Sugawara A, Tsuji H, Kodama S, Hsieh SD, Shimano H, Yamada N, Sone H
    • Organizer
      47th EASD Annual Meeting
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] New HbA1c 5.7-6.4% Criterion and Impaired Fasting Plasma Glucose To Identify Pre-Diabetes and Predict Risk of Diabetes in Japan (TOPICS)2011

    • Author(s)
      Heianza Y, Fujiwara K, Yoshizawa S, Hara S, Tsuji H, Hsieh SD, Kodama S, Saito K, Arase Y, Yamada N, Kosaka K, Sone H
    • Organizer
      71th American Diabetes Association Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] HbA1cとFPGによる糖代謝異常評価とその後の糖尿病発症リスク(TOPICS)2011

    • Author(s)
      原茂子, 平安座依子, 齋藤和美, 辻裕之, 児玉暁, 謝勲東, 島野仁, 荒瀬康司, 山田信博, 小坂樹徳, 曽根博仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 2型糖尿病のインスリン導入率とインスリン導入予知因子の探索2011

    • Author(s)
      山下りさ, 菅野咲子, 高橋直穂, 山田大志郎, 本庄潤, 曽根博仁, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] わが国における2型糖尿病患者の食事摂取の状況:Japan Diabetes Complication Study (JDCS)2011

    • Author(s)
      西垣結佳子, 田中司朗, 井藤英喜, 田中佐智子, 鎌田智恵実, 奥村亮太, 堀川千嘉, 片桐あかね, 大橋靖雄, 島野仁, 赤沼安夫, 山田信博, 曽根博仁, 吉村幸雄, JDCSグループ
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Potential impact of elevated HbA1c and impared fasting glucose on population for predicting risk of diabetes : The Toranomon Hospital Health Management Center Study2011

    • Author(s)
      Heianza Y, Hara S, Horikawa C, Saito K, Suga wara A, Fujiwara K, Kodama S, Hsieh SD, Tsuji H, Shimano H, Yamada N, Arase Y, Sone H
    • Organizer
      47th EASD Annual Meeting
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] PWVの改善に影響する介入因子の検討2011

    • Author(s)
      奥田昌恵, 猪苅冬樹, 高橋直穂, 佐藤舞菜見, 菅野咲子, 本庄潤, 山田大志郎, 曽根博仁, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 生涯最大体重や20歳時の体重はその後の未診断糖尿病や前糖尿病状態の発症と関連する(TOPICS)2011

    • Author(s)
      齋藤あき, 平安座依子, 原茂子, 齋藤和美, 辻裕之, 児玉暁, 近藤和雄, 荒瀬康司, 山田信博, 小坂樹徳, 曽根博仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 患者動向の10年間の推移2011

    • Author(s)
      畑中麻梨恵, 菅野咲子, 高橋直穂, 山田大志郎, 本庄潤, 曽根博仁, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] CT coronary angiography (CTA)による冠動脈不安定プラーク(VP)と関連する臨床指標に関する検討2011

    • Author(s)
      藤原和哉, 鈴木浩明, 佐藤明, 大崎芳典, 尾本美代子, 豊崎晶子, 平安座依子, 児玉暁, 齋藤和美, 小林和人, 矢藤繁, 高橋昭光, 山田信博, 曽根博仁, 島野仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Weight History as a screening tool for identifying undiagnosed deabetes and pre-diabetes in Japanese men (TOPICS)2011

    • Author(s)
      Yoshizawa S, Heianza Y, Fujihara K, hara S, Saito K, Tsuji H, Kodama S, Arase Y, Yamada N, Kosa ka K, Sone H
    • Organizer
      71th ADA Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 採血不要の臨床指標による未診断糖尿病予測スコアリングシステムの開発(TOPICS)2011

    • Author(s)
      由澤咲子, 平安座依子, 原茂子, 齋藤和美, 飯田薫子, 児玉暁, 謝勲東, 荒瀬康司, 山田信博, 小坂樹徳, 曽根博仁
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Dietary intake in Japanese patients with type 2 diabetes : Japan Diabetes Complication Study (JDCS)2011

    • Author(s)
      Horikawa C, Yoshimura Y, Nishigaki Y, Tanaka S, Tanaka S, Kamada C, Okumura R, Ito H, Ohashi Y, Yamada N, Sone H, Japan Diabetes Complication Study Group
    • Organizer
      71th American Diabetes Association Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Japan Diabetes Complication Study Group. Dietary intake in Japanese patients with type 2 diabetes : Japan Diabetes Complication Study (JDCS)2011

    • Author(s)
      Horikawa C, Yoshimura Y, Nishigaki Y, Tanaka S, Tanaka S, Kamada C, Okumura R, Ito H, Ohashi Y, Yamada N, Sone H
    • Organizer
      71th ADA Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] シタグリプチンの血糖改善効果は?-単剤投与,上乗せ,他剤交換の比較2011

    • Author(s)
      佐藤舞菜見, 高橋直穂, 今田敦子, 鈴木美佑希, 山田大志郎, 本庄潤, 曽根博仁, 中村公英, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-21
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] 1,5AGと受診時血糖値、A1cの関連-食後血糖抑制剤使用を含めた検討2011

    • Author(s)
      今田敦子, 菅野咲子, 高橋直穂, 山田大志郎, 本庄潤, 曽根博仁, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Evalution of clinical predictors of vuulnerable coronary plaque detected by CT angiography in asymptomatic patients with type 2 diabetes (T2DM)2011

    • Author(s)
      Fujihara K, Suzuki H, Sato A, Heianza Y, Kodama S, Saito K, Kobayashi K, Takahashi A, Yatou S, Yamada N, Sone H, Shimano H
    • Organizer
      71th American Diabetes Association Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Weight History as a screening tool for identifying undiagnosed deabetes and pre-diabetes in Japanese men (TOPICS)2011

    • Author(s)
      Yoshizawa S, Heianza Y, Fujihara K, Hara S, Saito K, Tsuji H, Kodama S, Arase Y, Yamada N, Kosaka K, Sone H
    • Organizer
      71th American Diabetes Association Scientific Sessions
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Japan Diabetes Complication Study (JDCS)における日本人2型糖尿病患者の栄養素及び食品摂取状況2011

    • Author(s)
      鎌田智英実, 西垣結佳子, 奥村亮太, 田中司朗, 井藤英喜, 田中佐智子, 堀川千嘉, 高橋あかね, 大橋靖雄, 赤沼安夫, 山田信博, 曽根博仁, 吉村幸雄, JDCSグループ
    • Organizer
      第65回日本栄養・食糧学会大会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-15
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] リラグルチドの多数例での有効無効の検討2011

    • Author(s)
      菅野咲子, 奥田昌江, 佐藤舞菜見, 山下りさ, 曽根博仁, 本庄潤, 山田大志郎, 横山宏樹
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-20
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Impact of introducing HbA1c into the diagnostic criteria and cardiovascular risk profiles of individuals with newly diagnosed diabetes2011

    • Author(s)
      Hara S, Heianza Y, Fujiwara K, Tsuji H, Hsieh SD, Kodama S, Saito K, Arase Y, Yamada N, Sone H
    • Organizer
      47th EASD Annual Meeting
    • Place of Presentation
      Lisbon, Portugal
    • Year and Date
      2011-09-13
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Comparison between Fasting and Post-Load Glucose Values as a Continuous Risk Factor for Cardiovascular Disease : A Meta-Analysis2010

    • Author(s)
      Kodama S, Horikawa C, Anasako Y, Saito K, Hirasawa R, Ibe Y, Yachi Y, Asumi M, Shimano H, Yamada N, Sone H
    • Organizer
      70^<th> ADA Scientific Sessions
    • Place of Presentation
      Orlando, Florida
    • Year and Date
      2010-06-27
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] The Japan Diabetes Complications Study(JDCS).2010

    • Author(s)
      曽根博仁, 赤沼安夫, 山田信博
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] Simple Self-Report Questions on Behavioral or Psychological Symptoms Can Effectively Predict Future Type2 Diabetes (T2DM) : Toranomon Hospital Health Management Center Study (TOPICS)2010

    • Author(s)
      Heianza Y, Nishigaki Y, Saito K, Totsuka K, Kodama S, Tsuji H, Hara S, Arase Y, Yamada N, Kosaka K, Sone H
    • Organizer
      70^<th> ADA Scientific Sessions
    • Place of Presentation
      Orlando, Florida
    • Year and Date
      2010-06-27
    • Data Source
      KAKENHI-PROJECT-20300227
  • [Presentation] メタボリックシンドロームと動脈硬化症の発症・進展2008

    • Author(s)
      山田信博
    • Organizer
      第80回日本医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2008-04-07
    • Data Source
      KAKENHI-PROJECT-18390268
  • 1.  ISHIBASHI Shun (90212919)
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 22.  SHIMADA Masako
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  • 25.  IKEUCHI Takeshi (20372469)
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  • 26.  ARAI Hidenori (60232021)
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  • 28.  MATSUBARA Hisahiro (20282486)
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  • 29.  KAWAI Koji (90272195)
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  • 30.  KASHIWA Atsushi (10301227)
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  • 31.  OYA Mototsugu (00213885)
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  • 32.  OHASHI Yasuo (00134461)
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  • 33.  NARUMIYA Shu (70144350)
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  • 34.  ANDO Joji (20159528)
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  • 35.  MARUYAMA Ikuro (20082282)
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  • 36.  IWAMOTO Yasuhiko (60143434)
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  • 37.  NAGATA Takuya (40303242)
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  • 39.  TSUKADA Kazuhiro (90171967)
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  • 40.  FAN Jianglin (60272192)
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  • 41.  SUGIYAMA Fumihiro (90226481)
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  • 42.  WATANABE Teruo (40037396)
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  • 48.  間野 博行 (90240704)
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  • 49.  中川 嘉 (80361351)
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  • 50.  松坂 賢 (70400679)
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  • 54.  飯田 薫子 (50375458)
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  • 57.  大沢 仲昭 (90010090)
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  • 58.  山田 明 (70175660)
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  • 59.  WATANABE Yoshiro
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  • 60.  SHIONOIRI Futoshi
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  • 61.  MIURA Yasuaki
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  • 62.  KOIKE Hiroyuki
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  • 63.  OHASHI Ken
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  • 64.  SUDOH Takako
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  • 65.  飯塚 陽子
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  • 66.  杢野 浩司
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  • 67.  高橋 照光
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  • 68.  范 江霖
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  • 69.  渡辺 照男
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