ENOMOTO Takemi 榎本武美

Researcher Number	80107383
Affiliation (based on the past Project Information) *help	2010 – 2016: Tohoku University, 薬学研究所, 教授 2007 – 2009: Tohoku University, Tohoku University, Graduate School of Pharmaceutical Sci., Professor 2006: 東北大学, 大学院薬学研究科, 教授 2001 – 2005: 東北大学, 薬学研究科, 教授 1999 – 2005: 東北大学, 大学院・薬学研究科, 教授 … More 2004: Tohoku Uni., Grad. Scihool Phan. Sci., Professor, 大学院薬学研究科, 教授 1995 – 1999: 東北大学, 薬学部, 教授 1994: 東京大学, 薬学部, 教授 1991 – 1994: 東京大学, 薬学部, 助教授 1989 – 1990: 東京大学, 薬学部, 講師 1987 – 1988: 東京大学, 薬学部, 助手 1986: Faculty of Pharmaceutical Sciences, University of Tokyo, Assistant professor., 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / Biological Sciences / 代謝生物化学 / Functional biochemistry Except Principal Investigator Biological pharmacy / 代謝生物化学 / Biological Sciences / Structural biochemistry
Keywords	Principal Investigator ブルーム症候群 / DNA複製 / WRN / BLM / ワーナー症候群 / 哺乳類細胞 / targeted integration / 老化 / WRNIP1 / ATM … More / SCE / DNAヘリカーゼ / Werner syndrome / RecQL1 / 酵母Sgs1 / Sgs1 / RecQヘリカーゼ / 癌 / DNAトポイソメラーゼIII / 酵母SGS1 / 胞子形成 / 温度感受性変異株 / Swiss 3T3 / SOD2 / SOD1 / DNA polymerase δ / homologous recombination / Top3 / Bloom syndrome / RecQL5 / 相同組換え / yeast Sgs1 / aging / WHIP / ヘリカーゼ / Bloom's syndrome / 癌化 / DNA helicase / DNA replication / SGS1 / RecQ / DNAヘリカーゼQ1 / 活性促進因子 / DNAポリメラーゼα / DNAまきもどし活性 / RECQL5 / 発がん抑制 / ウェルナー症候群 / Sgsl / 姉妹染色分体交換 / 精巣 / 減数分裂 / TPS1 / RecQホモローグ / DNA依存性ATPase / Primase / DNA polymerase <alpha> / in vitro reconstitution / プライマーゼ / in vitro再構成系 / reactive oxigen / cancer / gene / 糖尿病 / 活性酸素 / 遺伝子 / RecQ family helicase / progeria / 複製後修復 / RecQファミリーヘリケース / 早老症 / cartinogenesis / chromosome abberation / sister chromatid exchange / MRE11 / BASC / ゲノム / Xrcc3 / Top3α / SUMO化 / 発癌 / 相同組換え / 染色体異常 / homologous recobination / 阻害剤スクリーニング / targeted-integration / RecQファミリーヘリカーゼ / carcinogenesis / Helicase / RecQ family / Whip / Werner症候群 / RecQファミリー / SUMO-1 / yeast SGS1 / SUMO-1化 / Werner's syndrome / DNA topoisomerase III / Aging / Carcinogenesis / DNA helicase Q1 / RecQ protein / Rad18 / ウエルナー症候群 / RecQタンパク質 / mammalian cells / anti-cancer drug / screening / inhibitor / DNA-dependent ATPase / 抗癌剤 / スクリーニング / 阻害剤 / Meiosis / Spermatogenesis / Methyl methanesulfonate / Transgenic fly / DNA helicae Q1 / DNA repair-recombination / Rch1 / Two-hybrid system / 精子形成 / メチルメタンスルホン酸 / トランスジェニックフライ / DNA修復・組み換え / PI-3 kinase / GTP binding protein / thrombin / MAP kinase / Protein kinase Fa / Insulin / Swiss3T3 / プロティンキナーゼF_A / PI-3キナーゼ / GTP結合蛋白質 / トロンビン / MAPキナーゼ / プロテインキナーゼF_A / インスリン / DNAプライマーゼ / T抗原 / ポリオーマウイルス / RAD52 / ゲノム安定維持 / RECQL1 / 遺伝子組換え / ゲノム安定維持機構 / WRNTP1 / RAK18 / WPN / ユビキチン化 / 複製フォーク / DNA損傷回避 / RAD18 / 早期老化 / 障害回避 / 傷害回避 / DNA複製フォーク / RECL4 / RecQフミリーヘリカーゼ / ブルーム症侯群 / KNA組換え / RECQL4 / DNA傷害回避 / RecQファミリーヘレカーゼ / 姉妹染色分体接着 / DNA組換え / RecQファミリーへリカーゼ / ロスモンド・トムソン症候群 / チェックポイント / MSH2 / BLMヘリカーゼ / 蛍光染色 / 核内構造体 / 結合ドメイン / Wip1 / SUMO1 / Ubc9 / メチルメタンスルホン酸感受性 / RexQヘリカーゼ / cell-free DNA複製系 / RecD / ヘリカーゼモチーフ / DNAヘリカーゼB / 遺伝子破壊株 / アルキル化剤 / DNA修復 / cDNA / 一本鎖DNA結合蛋白 / プライマーRNA合成 / 細胞周期 / リン酸化 / DNAトポイソメラ-ゼII / DNAヘリカ-ゼ / C群 / XP / 色素性乾皮症 … More Except Principal Investigator 百日咳毒素 / GTP結合蛋白質 / 細胞増殖 / 情報伝達 / DNA修復 / 遺伝子 / 色素性乾皮症 / EAAC1 / CD98lc / CD98hc / CD98 / DNAポリメラーゼ / Cdc7 / NAD / 結晶化 / ブルーム症候群 / G蛋白質 / 修復酵素 / アデノウイルス / ポリオーマウイルス / DNA複製 / DNA腫瘍ウイルス / 核内癌遺伝子産物 / aging / cancer / genome instability / genetics / chicken DT40 / RecQ helicase / translesion DNA synthesis / homologous recombination / 2重鎖切断 / Rad18 / Werner症候群 / DT40 / 複製後修復 / WRNIPI1 / ポリメラーゼkappa / WRNヘリカーゼ / タモキシフェン / 染色体安定性 / Rev3 / H2AX / 複製フォーク停止 / 損傷乗り越え修復 / 相同組換え / ニワトリDT40 / 老化 / ゲノム / 癌 / 遺伝学 / Glutamate transporter / Tropomyosin / Monoclonal antibody / 細胞悪性化 / グルタミン酸トランスポーター / モノクローナル抗体(mAB) / トロポミオシン / グルタミン酸受容体 / EAACl / モノクローナル抗体 / Checkpoint control / Dbf4 protein kinase / Mcm2-7 complex / DNA helicase / Lagging strand synthesis apparatus / Leading strand synthesis apparatus / Eukaryotic chromosomal DNA replication / 細胞周期チェックポイント / PCNA / RF-C複合体 / Lagging鎖合成装置 / Leading鎖合成装置 / 真核生物染色体DNA複製 / Dbf4複合体 / Mcm蛋白複合体 / ヘリカーゼ / Bloom症候群原因遺伝子産物 / チェックポイント制御 / Dbf4プロテインキナーゼ / Mcm2-7蛋白複合体 / DNAヘリカーゼ / Lagging鎖複製装置 / Leading鎖複製装置 / 真核生物染色体複製機構 / signal transduction / radioimmunoassay / CD38 / ADP-ribosyl cyclase / NAD-cleavage enzyme / cyclic ADP-ribose / カルシウムイオン / ラジオイムノアッセイ / ヒトリンパ球表面抗原CD38 / ADPリボース環化酵素 / NAD代謝酵素 / 環状ADPリボース / DNA binding protein / DNA damages / protein structure / DNA repair / 遺伝情報 / 分子生物学 / DNA結合蛋白質 / DNA損傷 / 蛋白質の構造 / adrenergic receptor / pertussis toxin / protein tyrosine phosphorylation / PI 3-kinase / wortmannin / cell adhesion / cell differentiation / heterotrimeric G proteins / 3T3細胞 / HL-60細胞 / 細胞分化 / 肝蔵細胞 / Caチャネル / Gq / Gs / alpha_1アドレナリン受容体 / betaアドレナリン受容体 / 肝臓初代培養 / 3量体G蛋白質 / 細胞接着 / チロシンキナーゼ / ワ-トマニン / PI-3-キナーゼ / 食細胞 / 肝臓細胞 / 細胞膜受容体 / 百日咳素素(IAP) / 細胞周期 / 蛋白質のADPリボシル化 / 百日咳毒素(IAP) / ユビキチン / ts変異株 / DNA複製開始 / 増殖制御機構 / 突然変異株 / DNA合成 / 情報伝達系 / 正常細胞 / 変異株 / IAP / 増殖制御 / 大量発現系 / ヌクレオソーム構造変換 / X線結晶構造解析 / 大量発現 / 動的光散乱 / FACT / 精製 / ヒストンシャペロン / ヌクレオソーム / ヒストン / 結晶構造解析 / 組換えホットスポット / 二重鎖切断 / ウエルナ-症候群 / 結晶解析 / 不稔 / 接合伝達 / DNA複製フォーク / Rad54 / Mre11 / RuvABC / 減数分裂 / 相同的DNA組換え / MRC11タンパク質 / DMC1タンパク質 / RAD51タンパク質 / SOS反応 / hjc遺伝子 / RuvBタンパク質 / 組換え修復 / DNA組換え / トポイソメラーゼ / ウェルナ-症候群 / RecQヘリカーゼ / ミスマッチ修復酵素 / APEXヌクレアーゼ / 発癌性遺伝子突然変異 / 損傷認識抗体 / 紫外線DNA損傷 / 色素性乾皮症相補蛋白 / 色素性乾皮症遺伝子 / エリスロポエチンレセプター / リン脂質 / 脂溶性ビタミン / 免疫抑制 / 抗発癌プロモーター / 抗酸化剤 / ビタミン / エリスロポエチン / アレルゲン / 免疫 / 発がん抑制物質 / 抗酸化物質 / アトピー性皮膚炎 / 機能性食品 / 発現制御 / ADP-リボシル化 / 人為的変異導入法 / 癌転移 / 発癌性突然変異 / UV損傷に対する特異抗体 / 修復遺伝子 / 色素性乾皮症A群の遺伝子診断 / in vitro修復検出系 / UV誘発突然変異 / UV損傷単クロ-ン抗体 / DNA依存性ATPase / DNA除去修復 / A群色素性乾皮症相神遺伝子 / パピロ-マウイルス / ポリオ-マウイルス / パピローマウイルス Less

Analyses of function of RecQ helicase and its related proteins and detection of endogenous DNA damaging agentsPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Musashino University
Functions of RECQL1 and RECQL5 in the maintenance of genome stabilityPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Musashino University
Crystallographic analysis of the FACT-histone complex
- Principal Investigator
  
  SENDA Toshiya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Study on the functions of WRN and WRNIP1 that interacts with WRNPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Studies on the function of Werner syndrome gene product and analyses of the mechanism to induce aging related symptomsPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Functions of RecQ family helicases in DNA replication, repair, and damage avoidancePrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Molecular mechanism to couple DNA replication with avoidance of DNA lesions, the defect in which induces cancer and agingPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Reverse genetic study on replication, recombination, and replication using animal cell lines.
- Principal Investigator
  
  SONODA Eiichiro
- Project Period (FY)
  2001 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Molecular mechanism to cause high incidence of cancer in Bloom syndrcmePrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2001 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku Universty
ブルーム症候群の高発癌性の分子機構Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Development of a highly efficient method to integrate genes into genome of higher eukaryotic cells by homologous recombinationPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Molecular mechanism of the high incidence of cancer of Bloom's syndromePrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
Basic study on the mechanisms of carcinogenesis and aging with special reference to the function of RecQ family helicasesPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Analysis of CD98 Signal Transduction Related to Malignant Transformation
- Principal Investigator
  
  MASUKO Takashi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kinki University
  Tohoku University
ブルーム症候群の高発癌性の分子病理学的解析Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
SUMO1タンパク質を介するDNA修復・組み換え修復系の分子構築Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
Studies on the roles of RecQ family proteins in DNA repair and recombination in relation to carcinogenesis and agingPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
真核細胞RecQヘリカーゼのかかわる新規DNA修復系の解析
- Principal Investigator
  
  SEKI Masayuki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
DNA組換えと組換え修復の普遍的機構
- Principal Investigator
  
  品川日出夫
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Osaka University
Molecular Mechanism of Chromosomal DNA Replication Apparatus
- Principal Investigator
  
  SUGINO Akio
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Research Institute for Microbial Diseases, Osaka University
真核細胞の新規DNA修復系の検出と修復機構の解析Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
真核細胞のRecQホモローグの減数分裂における役割Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
DNAヘリカーゼを用いた哺乳類細胞のDNA複製の研究Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
Novel Mechanism & Developmental Roles of Repair・RecombinationPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Tohoku University
Establishment of the basis for developing inhibitors that target the DNA helicase involved in DNA replicationPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku University
哺乳類細胞のDNA複製に関与するDNAヘリカーゼの分子遺伝・生化学的研究Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Development of Assay Methods for a Novel Intracellular Messenger, Cyclic ADP-ribose
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo (Faculty of Pharmaceutical Sciences)
色素性乾皮症の修復欠損に関する遺伝子とタンパクの異常
- Principal Investigator
  
  藤原美定
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
哺乳類細胞のDNA複製に関与するDNAヘリカーゼの分子遺伝・生化学的研究Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Structure and function of DNA repair enzymes
- Principal Investigator
  
  YASUI Akira
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
色素性乾皮症の修復欠損に関する遺伝子とタンパク質の異常
- Principal Investigator
  
  藤原美定
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
細胞の腫瘍化における3量体G蛋白質の変異の役割
- Principal Investigator
  
  UI Michio
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
哺乳類細胞のDNA複製に関与するDNAヘリカーゼの分子遺伝・生化学的研究Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
食品の生体防御因子の解析と設計
- Principal Investigator
  
  小清水弘一
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kinki University
  Kyoto University
Signal Transduction Systems for Cell Proliferation, Differentiation and Adhesion with Emphasis upon the Role of GTP-binding Proteins
- Principal Investigator
  
  UI Michio
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  代謝生物化学
- Research Institution
  The Institute of Physical and Chemical Chemical Research (RIKEN)
  The University of Tokyo
Analysis of signal transduction of insulin with special reference to protein kinase FAPrincipal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  代謝生物化学
- Research Institution
  Tokyo University
色素性乾皮症の修復欠損に関わる遺伝子とタンパクの異常
- Principal Investigator
  
  藤原美定
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kobe University
トポインメラ-ゼIIの活性調節をする特異的蛋白質リン酸化酵素の研究Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
ウイルス癌遺伝子産物による細胞およびウイルスDNA複製の調節
- Principal Investigator
  
  吉池邦人
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  国立予防衛生研究所
色素性乾皮症細胞の欠損蛋白の同定とDNA除去修復機構の分子レベルでの解析Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
ウイルス癌遺伝子産物による細胞およびウイルスDNA複製の調節
- Principal Investigator
  
  吉池邦人
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  国立予防衛生研究所
細胞の増殖・分化を支配する情報伝達系ーGTP結合蛋白質とくに百日咳毒素(IAP)標的蛋白質の役割を中心にー
- Principal Investigator
  
  宇井理生
- Project Period (FY)
  1988 – 1991
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  The University of Tokyo
正常およびがん化細胞の増殖におけるGTP結合蛋白質の役割
- Principal Investigator
  
  宇井理生
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  The University of Tokyo
細胞増殖を支配する情報伝達系ーGTP結合蛋白質の関与を中心にー
- Principal Investigator
  
  宇井理生
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
哺乳類細胞のDNA複製開始制御機構の分子レベルでの解析Principal Investigator
- Principal Investigator
  
  榎本武美
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
突然変異株を用いた哺乳類細胞増殖制御機構の研究
- Principal Investigator
  
  花岡文雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  The University of Tokyo
Peconstitution and analysis of mammalian DNA replication system in vitro.Principal Investigator
- Principal Investigator
  
  ENOMOTO Takemi
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] 染色体サイクル(蛋白質核酸酵素別冊)2009
- Author(s)
  関政幸・Mong Sing Lai・榎本武美
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20390020
[Book] 蛋白質核酸酵素別冊;染色体サイクル2009
- Author(s)
  関政幸・Mong Sing Lai・榎本武美
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17013005
[Book] Reviews and protocols in DT40 research2006
- Author(s)
  Seki, M., Tada, S., Enomoto, T
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] The role of WRNIP1 in genome maintenance.2017
- Author(s)
  Yoshimura, A., Seki, M., and Enomoto, T.
- Journal Title
  
  Cell cycle
  
  Volume: 16 Issue: 6 Pages: 515-521
- DOI
  10.1080/15384101.2017.1282585
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440065, KAKENHI-PROJECT-15K07009
[Journal Article] Simultaneous depletion of WRNIP1 and RAD52 restores resistance to oxidative stress.2017
- Author(s)
  Yoshimura, A., Yabe, H., Akatani, M., Seki, M., and Enomoto, T.
- Journal Title
  
  Fundam. Toxicol. Sci.
  
  Volume: 4 Pages: 1-7
- NAID
  130005303928
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440065
[Journal Article] Excess Cdt1 inhibits nascent strand elongation by repressing the progression of replication forks in Xenopus egg extracts.2016
- Author(s)
  Nakazaki Y, Tsuyama T, Seki M, Takahashi M, Enomoto T, Tada S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 470 Issue: 2 Pages: 405-410
- DOI
  10.1016/j.bbrc.2016.01.028
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K07009, KAKENHI-PROJECT-15K07948, KAKENHI-PROJECT-26440065, KAKENHI-PROJECT-15H06638
[Journal Article] Roles of common subunits within distinct multisubunit complexes2014
- Author(s)
  Y. Nakabayashi, S. Kawashima, T. Enomoto, M. Seki, M. Horikoshi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 111 Issue: 2 Pages: 699-704
- DOI
  10.1073/pnas.1316433111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065, KAKENHI-PUBLICLY-24113703, KAKENHI-PROJECT-24370052
[Journal Article] Tumor suppressor RecQL5 controls recombination induced by DNA crosslinking agents2014
- Author(s)
  Yoshifumi Hosono, Takuya Abe, Masamichi Ishiai, M. Nurul Islam, Hiroshi Arakawa, Weidong Wang, Shunichi Takeda, Yutaka Ishii, Minoru Takata, Masayuki Seki, Takemi Enomoto
- Journal Title
  
  Biochimica et Biophysica Acta-Molecular Cell Research
  
  Volume: 1843 Issue: 5 Pages: 1002-1012
- DOI
  10.1016/j.bbamcr.2014.01.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-12J07075, KAKENHI-PLANNED-23114010, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-24310042, KAKENHI-PUBLICLY-25131706, KAKENHI-PROJECT-26550026, KAKENHI-PLANNED-22131002
[Journal Article] WRNIP1 functions upstream of DNA polymerase η in the UV-induced DNA damage response.2014
- Author(s)
  Yoshimura, A., Kobayashi, Y., Tada, S., Seki, M., Enomoto, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 452 Issue: 1 Pages: 48-52
- DOI
  10.1016/j.bbrc.2014.08.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590089, KAKENHI-PROJECT-26440065, KAKENHI-PLANNED-22131002
[Journal Article] Tipin Function in the Protection against Topoisomerase I Inhibitor2014
- Author(s)
  Yoshifumi Hosono, Takuya Abe, Masato Higuchi, Kosa Kajii, Shuichi Sakuraba, Shusuke Tada, Takemi Enomoto, Masayuki Seki
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 289 Issue: 16 Pages: 11374-11384
- DOI
  10.1074/jbc.m113.531707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07075, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-24590089, KAKENHI-PLANNED-22131002
[Journal Article] Protective roles of ascorbic acid in oxidative stress induced by depletion of superoxide dismutase in vertebrate cells2013
- Author(s)
  Tamari, Y., Nawata, H., Inoue, E., Yoshimura, A., Yoshii, H., Kashino, G., Seki, M., Enomoto, T., Watanabe, M., and Tano, K
- Journal Title
  
  Free Rad. Res
  
  Volume: 47 Issue: 1 Pages: 1-7
- DOI
  10.3109/10715762.2012.734916
- NAID
  120005398557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-24510072
[Journal Article] Embryonic lethality in mice lacking mismatch-specific thymine DNA glycosylase is partially prevented by DOPS a precursor of noradrenarine2012
- Author(s)
  Saito, Y., Ono, T., Takeda, N., Nohmi, T., Seki, M., Enomoto, T., Noda, T., and Uehara Y
- Journal Title
  
  Tohoku J. Exp. Med
  
  Volume: 226 Pages: 75-83
- Data Source
  KAKENHI-PROJECT-23370065
[Journal Article] Rmi1 functions in S phase-mediated cohesion establishment via a pathway involving the Ctf18-RFC complex and Mrc12012
- Author(s)
  Lai, M.S., Seki, M., Tada, S., and Enomoto, T
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 427 Pages: 682-686
- Data Source
  KAKENHI-PROJECT-23370065
[Journal Article] NIH3T3 cells overexpressing CD98 heavy chain resist early G1 arrest and apoptosis induced by serum starvation2012
- Author(s)
  Hara, K., Ueda, S., Ohno, Y., Tanaka, T., Yagi, H., Okazaki, S., Kawahara, R., Masayuki, T., Enomoto, T., Hashimoto, Y., Masuko, K., and Masuko, T
- Journal Title
  
  Cancer Sci
  
  Volume: 103
- Data Source
  KAKENHI-PROJECT-23370065
[Journal Article] Nucleosome surface containing nucleosomal DNA entry/exit site regulates H3-K36me3 via DNA entry/exit site regulates H3-K36me3 via2012
- Author(s)
  H.Endo, Y.Nakabayashi, S.Kawashima, T.Enomoto, M.Seki & M.Horikoshi
- Journal Title
  
  Genes Cells
  
  Volume: 17 Issue: 1 Pages: 65-81
- DOI
  10.1111/j.1365-2443.2011.01573.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PUBLICLY-22113502, KAKENHI-PROJECT-23370065, KAKENHI-PUBLICLY-24113703, KAKENHI-PROJECT-24370052
[Journal Article] An FD-LC-MS/MS proteomic strategy for revealing cellular protein networks : A conditional superoxide dismutase 1 knockout cells2012
- Author(s)
  Ichibangase, T., Sugawara, Y., Yamabe, A., Koshiyama, A., Yoshimura, A., Enomoto, T., and Imai, K
- Journal Title
  
  PLOS ONE
  
  Volume: 7 Issue: 9 Pages: e45483-e45483
- DOI
  10.1371/journal.pone.0045483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370065
[Journal Article] WRNIP1 accumulates at laser light irradiated sites rapidly via its ubiquitin-binding zinc finger domain and independently from its ATPase domain.2012
- Author(s)
  Nomura, H., Yoshimura, A., Edo, T., Kanno, S.I., Tada, S., Seki, M., Yasui, A., and Enomoto, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 417 Issue: 4 Pages: 1145-1150
- DOI
  10.1016/j.bbrc.2011.12.080
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23510059, KAKENHI-PROJECT-24590089, KAKENHI-PLANNED-22131005
[Journal Article] The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells2011
- Author(s)
  Abe, T., Yoshimura, A., Hosono, Y., Tada, S., Seki, M., Enomoto. T
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1813 Issue: 3 Pages: 473-479
- DOI
  10.1016/j.bbamcr.2011.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PROJECT-23370065
[Journal Article] Biphasic chromatin binding of FACT during DNA replication.2011
- Author(s)
  Kundu L.R., Seki M., Watanabe N., Murofusi H, Furukohri A., Waga S., Score A.J., Blow J.J., Horikoshi M., Enomoto T., Tada S.
- Journal Title
  
  Biochim.Biophys.Acta 1813
  
  Pages: 1129-1136
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] The role of SNM1 family nucleases in etoposide-induced apoptosis2011
- Author(s)
  Hosono, Y., Abe, T., Ishiai, M., Takata, M., Enomoto, T., Seki, M.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 410 Issue: 3 Pages: 568-573
- DOI
  10.1016/j.bbrc.2011.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21390094, KAKENHI-PLANNED-23114010, KAKENHI-PUBLICLY-23131505, KAKENHI-PROJECT-23370065, KAKENHI-PROJECT-23590380, KAKENHI-PROJECT-23651046
[Journal Article] The roles of histone chaperone CIA/Asf1 in nascent DNA elongation during nucleosome replication.2011
- Author(s)
  K.Ishikawa, T.Ohsumi, S.Tada, R.Natsume, L.R.Kundu, N.Nozaki, T.Senda, T.Enomoto, M.Horikoshi & M.Seki
- Journal Title
  
  Genes Cells
  
  Volume: 16 Issue: 10 Pages: 1050-1062
- DOI
  10.1111/j.1365-2443.2011.01549.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21590059, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22121005, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065
[Journal Article] Global analysis of core histones reveals nucleosomal surfaces required for chromosomebi-orientation2011
- Author(s)
  S.Kawashima, Y.Nakabayashi, K.Matsubara, N.Sano, T.Enomoto, K.Tanaka, M.Seki & M.Horikoshi
- Journal Title
  
  EMBO J.
  
  Volume: 30 Issue: 16 Pages: 3353-3367
- DOI
  10.1038/emboj.2011.241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21570193, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-23370065
[Journal Article] Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication2011
- Author(s)
  L.R.Kundu, M.Seki, H.Murofushi,A.Furukohri, S.Waga, A.J.Score, J.J.Blow, M.Horikoshi, T.Enomoto & S.Tada
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1813 Issue: 6 Pages: 1129-36
- DOI
  10.1016/j.bbamcr.2011.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21370075, KAKENHI-PUBLICLY-22113502, KAKENHI-PROJECT-23370065
[Journal Article] The histone chaperone FACT maintains replication fork rates2011
- Author(s)
  T.Abe, K.Sugimura, Y.Hosono, Y.Takami, M.Akita, A.Yoshimura, S.Tada, T.Nakayama, H.Murofushi, K.Okumura, S.Takeda, M.Horikoshi, M.Seki & T.Enomoto
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 35 Pages: 30504-30512
- DOI
  10.1074/jbc.m111.264721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-22380188, KAKENHI-PROJECT-22790281, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23370065
[Journal Article] Functional relationship between Claspin and Rad172011
- Author(s)
  Yoshimura, A., Akita, M., Hosono, Y., Abe, T., Kobayashi, M., Yamamoto, K.I., Tada, S., Seki, M., Enomoto, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 414 Issue: 2 Pages: 298-303
- DOI
  10.1016/j.bbrc.2011.09.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PROJECT-22710052, KAKENHI-PROJECT-23370065
[Journal Article] The N-terminal region of RECQL4 lacking the helicase domain is both essential and sufficient for the viability of vertebrate cells.2011
- Author(s)
  Abe T., Yoshimura A., Hosono Y., Tada S., Seki M., Enomoto T.
- Journal Title
  
  Biochim.Biophys.Acta 1813
  
  Pages: 473-479
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Werner interacting protein 1 promotes binding ofWerner protein to template-primer DNA2011
- Author(s)
  Kanamori, M., Seki, M., Yoshimura, A., Tsurimoto, T., Tada, S., and Enomoto, T.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34 Pages: 1314-1318
- Data Source
  KAKENHI-PROJECT-23370065
[Journal Article] Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2-7 complex.2010
- Author(s)
  Kundu L.R., Kumata Y., Kakusho N., Watanabe S., Furukohri A., Waga S., Seki M., Masai H., Enomoto T., Tada S.
- Journal Title
  
  Nucleic Acids Res. 38
  
  Pages: 5409-5418
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] RecQL5 promotes genome stabilization through two parallel mechanisms-interacting with RNA polymerase II and acting as a helicase.2010
- Author(s)
  Islam M.N., Fox D.III, Guo R., Enomoto T., Wang W.
- Journal Title
  
  Mol.Cell.Biol. 30
  
  Pages: 2460-2472
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] RecQL5 promotes genome stabilization trough two parallel mechanisms-Interacting with RNA polymerase II and acting as a helicase2010
- Author(s)
  Islam, M.N., Fox. D. III, Guo, R., Enomoto, T., Wang, W
- Journal Title
  
  Mol. Cell. Biol 30
  
  Pages: 2460-2472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] SOD1 is essential for the viability of DT40 cells and nuclear SOD1 functions as a guardian of genomic DNA.2010
- Author(s)
  Inoue E., Tano K., Yoshii H., Nakamura J., Tada S., Watanabe M., Seki M., Enomoto T.
- Journal Title
  
  J.Nuc.Acids (in press)
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Structure of the Cdt1 C-terminal domain: conservation of the winged helix fold in replication licensing factors2009
- Author(s)
  Khayrutdinov, B.I., Bae, W.J., Yun, Y.M., Lee, J.H., Tsuyama, T., Kim. J.J., Hwang, E., Ryu, K.S., Cheong, H.K., Cheong, C., Ko, J.S., Enomoto, T., Karplus, P.A., Guntert. P., Tada, S., Jeon, Y.H., Cho, Y
- Journal Title
  
  Protein Sci 18
  
  Pages: 2252-2264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD2.2009
- Author(s)
  Takada S., Inoue E., Tano K., Yoshii H., Abe T., Yoshimura A., Akita M., Tada S., Watanabe M., Seki M., Enomoto T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 379
  
  Pages: 233-238
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts2009
- Author(s)
  Tsuyama, T., Watanabe, S., Aoki, A., Cho, Y., Seki, M., Enomoto, T., Tada, S
- Journal Title
  
  Mol. Bio. Cell 20
  
  Pages: 937-947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Effect of heliquinomycin on the activity of human MCM4/6/7 helicase2009
- Author(s)
  Ishimi, Y., Sugiyama, T., Nakaya, R., Kanamori, M., Kohno, T., Enomoto, T., Chino, M
- Journal Title
  
  FEBS J 276
  
  Pages: 3382-3391
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Effect of heliquinomycin on the activity of human MCM4/6/7 helicase.2009
- Author(s)
  Ishimi Y., Sugiyama T., Nakaya R., Kanamori M., Kohno T., Enomoto T., Chino M.
- Journal Title
  
  FEBS J. 276
  
  Pages: 3382-3391
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Alternative title: Generation and characterization of cells that can be conditionally depleted of mitochondrial SOD22009
- Author(s)
  Takada, S., Inoue, E., Tano, K., Yoshii, H., Abe, T., Yoshimura, A., Akita, M., Tada, S., Watanabe, M., Seki, M., Enomoto, T
- Journal Title
  
  Biochem. Biophys. Res. Commun 379
  
  Pages: 233-238
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication2009
- Author(s)
  Ohuchi, T., Seki, M., Kugou, K., Tada, S., Ohta, K., Enomoto, T
- Journal Title
  
  DNA Repair 8
  
  Pages: 690-696
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Global analysis of mutual interaction surfaces of nucleosomes with comprehensive point mutants2009
- Author(s)
  Sakamoto, M., Noguchi, S., Kawashima, S., Okada, Y., Enomoto, T., Seki, M., Horikoshi, M
- Journal Title
  
  Genes Cells 14
  
  Pages: 1271-1330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Accumulation of sumoylated Rad52 in checkpoint mutants perturbed in DNA replication.2009
- Author(s)
  Ohuchi T., Seki M., Kugou K., Tada S., Ohta K., Enomoto T.
- Journal Title
  
  DNA Repair 8
  
  Pages: 690-696
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Physical and functional interaction between WRNIP1 and RAD18.2009
- Author(s)
  Yoshimura A., Seki M., Kanamori M., Tateishi S., Tsurimoto T., Tada S., Enomoto T.
- Journal Title
  
  Genes Genet.System 84
  
  Pages: 171-178
- NAID
  10024791852
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.2009
- Author(s)
  Tsuyama T., Watanabe S., Aoki A., Cho Y., Seki M., Enomoto T., Tada S.
- Journal Title
  
  Mol.Bio.Cell 20
  
  Pages: 937-947
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase IIIa.2008
- Author(s)
  Otsuki M., Seki M., Inoue E., Abe T., Narita Y., Yoshimura A., Tada S., Ishii Y., Enomoto T.
- Journal Title
  
  Biochim.Biophys.Acta 1782
  
  Pages: 75-81
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation2008
- Author(s)
  Abe, T., Ishiai, M., Hosono, Y., Yoshimura, A., Tsuji, H., Tada, S., Adachi, N., Koyama, H., Takata, M., Takeda, S., Enomoto, T., Seki, M
- Journal Title
  
  Cell Signal 20
  
  Pages: 1978-1985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Vertebrate WRNIP1 and BLM are required for efficient maintenance of genome stability.2008
- Author(s)
  Hayashi T., Seki M., Yoshimura A., Inoue E., Kusa Y., Tada S., Enomoto T.
- Journal Title
  
  Genes Genet.Syst. 83
  
  Pages: 95-100
- NAID
  10024395708
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Nuclear localization of Rad52 is pre-requisite for its sumoylation2008
- Author(s)
  Ohuchi, T., Seki, M., Enomoto, T
- Journal Title
  
  Biochem. Biophys. Res. Commun 372
  
  Pages: 126-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] A novel function for Rad17 in homologous recombination2008
- Author(s)
  Nishino, K., Inoue, E., Takada, S., Abe, T., Akita, M., Yoshimura, A., Tada, S., Kobayashi, M., Yamamoto, K., Enomoto, T
- Journal Title
  
  Genes Genet. Syst 83
  
  Pages: 427-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Analyses of functional interaction between RECQL1, RECQL5, and BLM which physically interact with DNA topoisomerase III・2008
- Author(s)
  Otsuki, M., Seki, M., Inoue, E., Abe. T., Narita, Y., Yoshimura, A., Tada, S., Ishii, Y., Enomoto, T
- Journal Title
  
  Biochim. Biophys. Acta 1782
  
  Pages: 75-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability.2008
- Author(s)
  Xu D., Guo R., Sobeck A., Bachrati C.Z., Yang J., Enomoto T., Brown G.W., Hoatlin M.E., Hickson I.D., Wang W.
- Journal Title
  
  Gene Dev. 22
  
  Pages: 2843-2855
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Rad52 sumoylation and its involvement in the efficient induction of homologous recombination2008
- Author(s)
  Ohuchi, T., Seki, M., Branzei, D., Maeda, D., Ui, A., Ogiwara, H., Tada, S., Enomoto, T
- Journal Title
  
  DNA Repair 7
  
  Pages: 879-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Nuclear localization of Rad52 is pre-requisite for its sumoylation.2008
- Author(s)
  Ohuchi T., Seki M., Enomoto T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 372
  
  Pages: 126-130
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] KU70/80, DNA-PKcs, and Artemis are essential for the rapid induction of apoptosis after massive DSB formation.2008
- Author(s)
  Abe T., Ishiai M., Hosono Y., Yoshimura A., Tsuji H., Tada S., Adachi N., Koyama H., Takata M., Takeda S., Enomoto T., Seki M.
- Journal Title
  
  Cell Signal. 20
  
  Pages: 1978-1985
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] Rad52 sumoylation and its involvement in the efficient induction of homologous recombination.2008
- Author(s)
  Ohuchi T., Seki M., Branzei D., Maeda D., Ui A., Ogiwara H., Tada S., Enomoto T.
- Journal Title
  
  DNA Repair 7
  
  Pages: 879-889
- Data Source
  KAKENHI-PROJECT-20390020
[Journal Article] RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability2008
- Author(s)
  Xu, D., Guo, R., Sobeck, A., Bachrati, C.Z., Yang, J., Enomoto, T., Brown, G.W., Hoatlin, M.E., Hickson, I.D., Wang W
- Journal Title
  
  Gene Dev 22
  
  Pages: 2843-2855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] INO80 chromatin remodeling complex functions in sister chromatid cohesion2007
- Author(s)
  Ogiwara, H., Enomoto, T., Seki, M
- Journal Title
  
  Cell Cycle 6
  
  Pages: 1090-1095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Chl1 and Ctf4 are required for damage-induced recombinations. Biochem2007
- Author(s)
  Ogiwara, H., Ui, A., Lai M.S., Enomoto, T., Seki M
- Journal Title
  
  Biophys. Res. Commun 354
  
  Pages: 222-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts2007
- Author(s)
  Kumata, Y., Tada, S., Yamanada, Y., Tsuyama, T., Kobayashi, T., Dong, Y. -P., Ikegami, K., Murofushi, H., Seki, M., Enomoto, T
- Journal Title
  
  Biochim. Biophys. Acta 1773
  
  Pages: 556-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Functional interactions between BLM and XRCC3 in the cell2007
- Author(s)
  Otsuki, M., Seki, M., Inoue, E., Yoshimura, A., Kato, G., Yamanouchi, S., Kawabe, Y., Tada, S., Shinohara, A., Komura, J., Ono, T., Takeda, S., Ishii, Y., Enomoto, T
- Journal Title
  
  J. Cell Biol 179
  
  Pages: 53-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Rmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesion2007
- Author(s)
  Lai M.S., Seki, M., Ui, A., Enomoto, T
- Journal Title
  
  EMBO Reports 8
  
  Pages: 685-690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] INO80 complex is required for damage-induced recombination2007
- Author(s)
  Kawashima, S., Ogiwara, H., Tada, S., Harata, M., Wintersberger, U., Enomoto, T., Seki, M
- Journal Title
  
  Biochem. Biophys. Res. Commun 355
  
  Pages: 835-841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Role of Elg1 protein in the double-strand breaks repair2007
- Author(s)
  Ogiwara, H., Ui, A., Enomoto, T., Seki, M
- Journal Title
  
  Nuc. Acids Res 35
  
  Pages: 353-362
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Actin-related protein Arp4 functions in kinetochore construction2007
- Author(s)
  Ogiwara, H., Ui, A., Kawashima, S., Kugou, K., Onoda, F., Iwahashi, H., Harata, M., Ohta, K., Enomoto, T., Seki, M
- Journal Title
  
  Nuc. Acids Res 35
  
  Pages: 3109-3117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Rad50 is involved in MMS-induced recombination between homologous chromosomes in mitotic cells2007
- Author(s)
  Tomizawa, Y., Ui, A., Onoda, F., Ogiwara, H., Tada, S., Enomoto, T., Seki, M
- Journal Title
  
  Genes Genet. Syst 82
  
  Pages: 157-160
- NAID
  10024394124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Activation of a novel pathway involving Mms1 and Rad59 in sgs1 cells2007
- Author(s)
  Ui, A., Seki, M., Ogiwara, H., Lai, M.S., Yamamoto, K., Tada, S., Enomoto, T
- Journal Title
  
  Biochem. Biophys. Res. Commun 356
  
  Pages: 1031-1037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Ctf18 is required for homologous recombination -mediated double strand break repair2007
- Author(s)
  Ogiwara, H., Ohuchi, T., Ui, A., Tada, S., Enomoto, T., Seki, M
- Journal Title
  
  Nuc. Acids Res 35
  
  Pages: 4989-5000
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Ames test-negative carcinogen, ortho-phenyl phenol, binds tubulin and causes aneuploidy in budding yeast2007
- Author(s)
  Nunoshiba, T., Watanabe, E., Takahashi, T., Daigaku., Y., Ishikawa, S., Mochizuki, M., Ui, A., Enomoto, T., Yamamoto, K
- Journal Title
  
  Mut. Res 617
  
  Pages: 90-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Mgs1 and Rad18/Rad5/Mms2 are required for survival of novel temperature/cold sensitive mutant alleles of Pol31, the second subunit of DNA polymerase・, in Saccharomyces cerevisiae2006
- Author(s)
  Davoodi Vijeh Motlagh, N., Branzei, D., Seki, M., Enomoto, T
- Journal Title
  
  DNA Repair 5
  
  Pages: 1459-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] BLM is an early responder to DNA double-strand breaks. Biochem. Biophys2006
- Author(s)
  Karmakar, P., Seki, M., Kanamori, M., Hashiguchi, K., Ohtsuki, M., Murata, E., Inoue, E., Tada, S., Lan, L., Yasui, A., Enomoto, T
- Journal Title
  
  Res. Commun 348
  
  Pages: 62-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Dpb11, the budding yeast homologue of TopBP1, functions with the checkpoint clamp in recombination repair2006
- Author(s)
  Ogiwara, H., Ui, A., Onoda, F., Tada, S., Enomoto, T., Seki, M
- Journal Title
  
  Nuc. Acids Res 34
  
  Pages: 3389-3398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Loss of heterozygosity in yeast can occur by ultraviolet irradiation during the S phase of the cell cycle2006
- Author(s)
  Daigaku, Y., Mashiko, S., Mishiba, K., Yamamura, S., Ui, A., Enomoto, T., Yamamoto, K
- Journal Title
  
  Mutat. Res 600
  
  Pages: 177-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Bloom helicase and DNA topoisomerase III・are involved in the dissolution of sister chromatids2006
- Author(s)
  Seki, M., Nakagawa, T., Seki, T., Kato, G., Tada, T., Takahashi, Y., Yoshimura, A., Kobayashi, T., Aoki, A., Otsuki, M., Habermann, F.A., Tanabe, H., Ishii, Y., Enomoto, T
- Journal Title
  
  Mol. Cell. Biol 26
  
  Pages: 6299-6307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] A novel Rad18 function involved in the protection of the vertebrate genome after exposure to camptothecin2006
- Author(s)
  Yoshimura, A., Nishino, K., Takezawa, J., Tada, S., Kobayashi, T., Sonoda, E., Kawamoto, T., Takeda, S., Ishii, Y., Yamada, K., Enomoto, T., Seki, M
- Journal Title
  
  DNA Repair 5
  
  Pages: 1307-1316
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Ubc9 and Mms21 mediated sumoylation counteracts recombinogenic events at damaged replication forks2006
- Author(s)
  Branzei, D., Sollier, J., Liberi, G., Zhao, X, Maeda, D., Seki, M., Enomoto, T., Ohta, K., Foiani, M
- Journal Title
  
  Cell 127
  
  Pages: 509-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Chromatin loading of Smc5/6 is induced by DNA replication but not by DNA double-strand breaks2006
- Author(s)
  Tsuyama, T., Inou, K., Seki, M., Seki, T., Kumata, Y., Kobayashi, T., Kimura, K., Hanaoka, F., Enomoto, T., Tada, S
- Journal Title
  
  Biochem. Biophys. Res. Commun 351
  
  Pages: 935-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] DNA topoisomerase III is essential for damage-induced recombination2005
- Author(s)
  Ui, A., Seki, M., Ogiwara, H., Onodera, R., Fukushige, S., Onoda, F., Enomoto, T
- Journal Title
  
  DNA Repair 4
  
  Pages: 191-201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Human Werner helicase interacting protein 1 (WRNIP1) functions as a novel modulator for DNA polymerase・・2005
- Author(s)
  Tsurimoto, T., Shinozaki, A., Yano, M., Seki, M., Enomoto, T
- Journal Title
  
  Genes Cells 10
  
  Pages: 13-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Caenorhabditis elegans geminin homologue participates in cell cycle regulation and germ line development2005
- Author(s)
  Yanagi, K., Mizuno, T., Tsuyama, T., Tada, S., Iida, Y., Sugimoto, A., Eki, T., Enomoto, T., Hanaoka F
- Journal Title
  
  J. Biol. Chem 280
  
  Pages: 19689-19694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Journal Article] Functional relationships of FANCC to homologous recombination, translesion synthesis, and BLM2005
- Author(s)
  Hirano, S., Yamamoto, K., Ishiai, M., Yamazoe, M., Seki, M., Matsushita, N., Ohzeki, M., Yamashita, Y.M., Arakawa, H., Buerstedde, J. -M., Enomoto, T., Takeda, S., Thompson, L.H., Takata, M
- Journal Title
  
  EMBO J 24
  
  Pages: 418-427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] WRNIP1によるPrimPolの発現調節2017
- Author(s)
  吉村明、神保仁美、長谷川有里、関政幸、榎本武美
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] WRNIP1とPrimPolの機能的関連の解析2016
- Author(s)
  吉村明、追川瑞穂、関政幸、榎本武美
- Organizer
  第89回日本生化学大会
- Place of Presentation
  東北大学（仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] WRNIP1/RAD52 遺伝子破壊株の作製と解析2016
- Author(s)
  吉村明、矢部晴菜、関政幸、榎本武美
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] Werner interacting protein 1(WRNIP1)とPrimPolの相互作用の解析2015
- Author(s)
  追川瑞穂、吉村明、榎本武美
- Organizer
  第５９回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] WRNIP1のC末領域がPolη破壊株のUV感受性の制御に関与する2015
- Author(s)
  吉村明、榊原達也、多田周右、関政幸、榎本武美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大（神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] DNA損傷時にWRNIP1はPrimPolと結合する2015
- Author(s)
  吉村明、追川瑞穂、関政幸、榎本武美
- Organizer
  第37回日本分子生物学会年会、第88回日本生化学大会合同大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] Cdt1によるDNA複製抑制作用に関する各種欠失変異体を用いた解析2014
- Author(s)
  中崎祐太、牛田麻理、津山崇、関政幸、榎本武美、多田周右
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] WRNIP1/Polη二重破壊株で作動するUV損傷回避／修復経路の解析2014
- Author(s)
  吉村明、多田周右、関政幸、榎本武美
- Organizer
  第87回日本生化学大会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26440065
[Presentation] WRNIP1 regulates DNA polymerase eta in DNA damage tolerance2013
- Author(s)
  吉村明, 薗田覚, 関政幸, 榎本武美
- Organizer
  第86回日本生化学大会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2013-09-13
- Data Source
  KAKENHI-PROJECT-23370065
[Presentation] Function of RecQL5 helicase in interstrand crosslink repair2012
- Author(s)
  Yoshifumi Hosono, Masayuki Seki, Takuya Abe, Masamichi Ishiai, Shunichi Takeda, Ishii Yutaka, Minoru Takata, Takemi Enomoto
- Organizer
  The 8th 3R Symposium
- Place of Presentation
  淡路夢舞台(淡路市)
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-23370065
[Presentation] RecQヘリカーゼのDNAクロスリンク修復における役割2012
- Author(s)
  細野嘉史, 関政幸, 阿部拓也, 石合正道, 武田俊一, 石井裕, 高田穣, 榎本武美
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡市)
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23370065
[Presentation] Analysis of the functional relationship between WRNIP1 and DNA polymerase eta in the cell2011
- Author(s)
  吉村明, 関政幸, 榎本武美
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23370065
[Presentation] DNAヘリカーゼRecQL5の相同組換え機構における機能の解析2011
- Author(s)
  細野嘉史, 阿部拓也, 関政幸, 榎本武美
- Organizer
  DNAヘリカーゼRecQL5の相同組換え機構における機能の解析
- Place of Presentation
  サンピア福岡(福津市)
- Year and Date
  2011-10-25
- Data Source
  KAKENHI-PROJECT-23370065
[Presentation] WRNIP1(WRN結合タンパク質)とRAD18の相互作用の解析2009
- Author(s)
  吉村明、立石智、関政幸、榎本武美
- Organizer
  遺伝学研究所研究集会
- Place of Presentation
  遺伝学研究所(三島市)
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] The role of FACT in DNA replication2009
- Author(s)
  Takemi Enomoto
- Organizer
  Swiss-Japan joint metting on the molecular mechanisms regulating "Chromosome dynamics and Genome stability"
- Place of Presentation
  Villars Ollons, Switzerland
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] WRNIP1のRAD18-RAD6複合体への結合と複合体のDNA結合に及ぼす影響2009
- Author(s)
  吉村明、金森允、多田周右、立石智、関政幸、榎本武美
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都国際会議場(京都市)
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] DNA複製チェックポイント因子ClaspinとRad17の機能的関連の解析2009
- Author(s)
  細野嘉史、榎本武美
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] The role of FACT in DNA replication(招待講演)2009
- Author(s)
  榎本武美
- Organizer
  Swiss-Japan joint meeting on the molecular mechanisms regulating "Chromosome dynamics and genome stability"
- Place of Presentation
  Villars Ollons(スイス)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] ヒストンシャペロンFACTのDNA複製における機能解析2009
- Author(s)
  阿部拓也、榎本武美
- Organizer
  第6回東北大学バイオサイエンスシンポジウム
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] The role of FACT in DNA replication2009
- Author(s)
  Enomoto, T.
- Organizer
  Swiss-Japan joint meeting on the molecular mechanisms regulating "Chromosome dynamics and genome stability"
- Place of Presentation
  Villars Ollons(スイス)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] Acetylation of histone H3-K56 regulates homologous recombination2009
- Author(s)
  遠藤博人、榎本武美
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] Nuclear superoxide may trigger spontaneous sister chromatid exchanges(招待講演)2009
- Author(s)
  井上絵里、榎本武美
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] 親鎖ヌクレオソーム中のヒストン成分の娘鎖への分配機構解明に向けて(招待講演)2009
- Author(s)
  石川勝幸、榎本武美
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] A mutant protein of histone chaperone CIA/Asf1 defective in disrupting histone(H3-H4)_2 tetramer accelerates rate of DNA replication2009
- Author(s)
  大隅達也、榎本武美
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] Analysis of DNA replication repression by excess Cdt12009
- Author(s)
  牛田磨理、榎本武美
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] DNA複製に必須なCdc45の新規機能の解析2009
- Author(s)
  大隅達也、榎本武美
- Organizer
  第48回日本薬学会東北支部大会
- Place of Presentation
  東北薬科大学(仙台)
- Year and Date
  2009-10-18
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] RecQL4のDNA二本鎖切断誘発時における挙動の解析2008
- Author(s)
  池上京子、多田周右、Li Lan、安井明、関政幸、榎本武美
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] WRNIP1はRAD18-RAD6に結合し、RAD18-RAD6のもつ複製フォーク様構造への結合を阻害する2008
- Author(s)
  吉村明、金森允、多田周右、立石智、関政幸、榎本武美
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20390020
[Presentation] ブルーム症候群原因遺伝子産物BLMのDNA複製及び姉妹染色分体接着における役割2008
- Author(s)
  榎本武美
- Organizer
  日本環境変異原学会第37回大会
- Place of Presentation
  沖縄県宜野湾
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] ブルーム症候群原因遺伝子産物BLMのDNA複製及び姉妹染色分体接着における役割(Functions of the Bloom syndrome responsible gene product in DNA replication and sister chromatid cohesion)2008
- Author(s)
  榎本武美
- Organizer
  日本環境変異原学会第37回大会
- Place of Presentation
  沖縄
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] Rmi1, a member of the Sgs1-Top3 complex in budding yeast, contributes to sister chromatid cohesion2008
- Author(s)
  Mong Sing Lai, Masayuki Seki, Ayako Ui, Takemi Enomoto
- Organizer
  2008 EMBO conference on DNA recombination
- Place of Presentation
  Cioccol, Italy
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] Illegitimate activation of Cdt1 at S-phase possibly leads to a halt of nascent strand elongation in DNA re-replication2007
- Author(s)
  Shusuke Tada, Masayuki Seki, Takemi Enomoto
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] Rmi1/Nce4, a subunit of the Sgs1-Top3 complex of Saccharomyces cerevisiae is involved in homologous recombination and establishment of sister chromatid cohesion2006
- Author(s)
  Mong Sing Lai、宇井彩子、関政幸、榎本武美
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Year and Date
  2006-03-29
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] DNA二本鎖切断修復におけるRecQL4の機能の解析2006
- Author(s)
  山名田弓枝、多田周右、二藤望、熊田裕司、小林貴之、関政幸、榎本武美
- Organizer
  日本薬学会第126年会
- Place of Presentation
  仙台
- Year and Date
  2006-03-28
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] BLM functions together with XRCC3 for resumption of stalled replication forks2006
- Author(s)
  Makoto Otsuki, Masayuki Seki, Eri Inoue, Genta Katoh, Akari Yoshimura, Shusuke Tada, Yutaka Ishii, Shunichi Takeda, Takemi Enomoto
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-18
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] BLM is an early responder to DNA double strand breaks2005
- Author(s)
  Parimal Karmakar, Masayuki Seki, Makoto Kanamori, Shusuke Tada, Li Lan, Kazunari Hashiguchi, Akira Yasui, Takemi Enomoto
- Organizer
  The 5th Symposium on DNA Replication, Recombination and Repair
- Place of Presentation
  Hyogo
- Year and Date
  2005-11-13
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] BLM acts together with XRCC3 upon damage induction2005
- Author(s)
  Makoto Otsuki, Masayuki Seki, Genta Kato, Eri Inoue, Akari Yoshimura, Shusuke Tada, Takemi Enomoto
- Organizer
  第78回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2005-10-22
- Data Source
  KAKENHI-PROJECT-17013005
[Presentation] ブルーム症候群原因遺伝子産物の機能の解析2005
- Author(s)
  関政幸、多田周右、榎本武美
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-14
- Data Source
  KAKENHI-PROJECT-17013005

1. MASUKO Takashi (30157200)

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2. UI Michio (50001037)

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ENOMOTO Takemi 榎本 武美

Research Projects

Research Products

Co-Researchers

Analyses of function of RecQ helicase and its related proteins and detection of endogenous DNA damaging agentsPrincipal Investigator

Principal Investigator

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Research Institution

Functions of RECQL1 and RECQL5 in the maintenance of genome stabilityPrincipal Investigator

Principal Investigator

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Research Institution

Crystallographic analysis of the FACT-histone complex

Principal Investigator

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Research Institution

Study on the functions of WRN and WRNIP1 that interacts with WRNPrincipal Investigator

Principal Investigator

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Research Institution

Studies on the function of Werner syndrome gene product and analyses of the mechanism to induce aging related symptomsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Functions of RecQ family helicases in DNA replication, repair, and damage avoidancePrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Molecular mechanism to couple DNA replication with avoidance of DNA lesions, the defect in which induces cancer and agingPrincipal Investigator

Principal Investigator

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Reverse genetic study on replication, recombination, and replication using animal cell lines.

Principal Investigator

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Molecular mechanism to cause high incidence of cancer in Bloom syndrcmePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ブルーム症候群の高発癌性の分子機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a highly efficient method to integrate genes into genome of higher eukaryotic cells by homologous recombinationPrincipal Investigator

Principal Investigator

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Research Institution

Molecular mechanism of the high incidence of cancer of Bloom's syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Basic study on the mechanisms of carcinogenesis and aging with special reference to the function of RecQ family helicasesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

ENOMOTO Takemi 榎本武美