Mashimo Tomoji 真下知士

… Alternative Names

MASHIMO Tomoji 真下知士

Less

Researcher Number	80397554
Other IDs	https://orcid.org/0000-0001-7543-7301
External Links
Affiliation (Current)	2025: 東京大学, 医科学研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 東京大学, 医科学研究所, 教授 2015 – 2020: 大阪大学, 医学系研究科, 准教授 2018: 大阪大学, 大学院医学系研究科, 准教授 2017: 京都大学, 大学院医学研究科, 准教授 2017: 大阪大学, 大学院医学系研究科附属動物実験施設, 准教授 … More 2016: 大阪大学, 大学院医学研究科, 准教授 2016: 大阪大学, 大学院医学系研究科, 准教授 2015 – 2016: 大阪大学, 医学(系)研究科(研究院), 准教授 2014: 京都大学, 医歯学系, 准教授 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 准教授 2013: 京都大学, 大学院医学研究科附属動物実験施設, 特定准教授 2012: 京都大学, 大学院・医学研究科, 特定准教授 2011: 京都大学, 医学系研究科, 准教授 2009 – 2011: Kyoto University, 医学研究科, 特定准教授 2008: 京都大学, 医学研究科, 准教授 2007 – 2008: Kyoto University, Graduate School of Medicine, Research Associate Professor 2005 – 2006: 京都大学, 医学研究科, COE助教授 Less
Review Section/Research Field	Principal Investigator Laboratory animal science / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Medium-sized Section 90:Biomedical engineering and related fields / Laboratory animal science Except Principal Investigator Laboratory animal science / Risk sciences of radiation and chemicals / Medium-sized Section 63:Environmental analyses and evaluation and related fields / Pediatrics / Basic Section 56060:Ophthalmology-related … More / Basic Section 57070:Developmental dentistry-related / Metabolomics / Intelligent informatics / Otorhinolaryngology / Integrative animal science / Molecular biology / Basic / Social brain science / Experimental pathology / Kidney internal medicine Less
Keywords	Principal Investigator ゲノム編集 / ラット / 疾患モデル / 受精卵 / CRISPR-Cas3 / 診断薬 / 遺伝子 / ポジショナルクローニング / マウス / in vivoゲノム編集 … More / 脂質ナノ粒子 / 遺伝子改変マウス / コラテラル切断 / 原子間力顕微鏡 / モデル動物 / 核酸検出法 / in vivoゲノム編 / in vitroゲノム編集 / マウス受精卵 / CRISPR/Cas / 培養細胞 / CRISPR-Cas / DNA修復 / オフターゲット / 肝移植 / 免疫不全ラット / iPS細胞 / ヒト肝細胞 / 実験動物 / 脳神経疾患 / ENUミュータジェネシス / ENU ミュータジェネシス / てんかん / メッセンジャーRNA / ゲノムDNA / スクリーニング / トランスポゾンMu / ミュータジェネシス / トランスジェニック / 遺伝解析 / 運動失調 / プルキンエ細胞 / 小脳 … More Except Principal Investigator ゲノム編集 / 遺伝子改変ラット / 疾患モデル / ラット / てんかん / DNA修復欠損性疾患 / ゲノムインスタビリティ / 分子探索・プロファイリング / 分子プロファイリング / 生理機能解析 / 病理形態解析 / モデル動物作製 / 修復 / DNA修復 / 放射線発がん / 高血圧 / 疾患モデル動物 / 実験動物 / オントロジー / 情報統合 / 表現型 / マルチオミクス解析 / 損傷DNA修復・損傷応答機構 / 環境ストレス / がん・老化関連疾患 / DNA修復・転写共役修復 / 環境ストレス・環境変異原 / 角膜内皮細胞 / フックス角膜内皮ジストロフィ / リピート病 / 行動解析 / 分子探索・ブロファイリング / 遺伝子変異 / ゲノム / 口唇口蓋裂 / Gata3 / レチノイン酸シグナル / ゲノム解析 / 動物モデル / 希少疾患 / 顎顔面形成不全 / 増幅経路 / 惹起経路 / インスリン顆粒 / グルコース応答性 / 糖尿病 / インクレチン分泌 / インスリン分泌 / 知識抽出 / 知識モデル / 生命科学 / 科学データ / 生命科学データ / 知識の相互利用 / 計測データ / ロール概念 / 視点転換 / 大規模データ / オープンデータ / 分野横断 / 相互利用 / 転写共役修復 (TC-NER) / 次世代オミクス解析 / DNA損傷応答 / ゲノム不安定性疾患 / transgenic mice / oral HPV infection / human papillomavirus / 癌 / ウイルス / CRISPR/Cas9 / liquid biopsy / 咽頭感染率 / トランスジェニックマウス / リキッドバイオプシー / 咽頭感染 / 中咽頭癌 / ヒトパピローマウイルス / miR181a / 胚中心 / 老化関連T細胞 / 自己抗体 / 自己免疫疾患 / 貪食 / 死細胞処理 / 全身性エリテマトーデス / オステオポンチン / CD153 / PD-1 / T細胞 / 免疫老化 / 遺伝子改変動物 / シグネチャ変異トレーシング / 変異追跡 / 改変ラット / 生物影響 / ラットモデル / 放射線 / 変異 / 発がん / 放射線影響 / DNA損傷 / 転写と共役したヌクレオチド除去修復 / 連合学習 / 光遺伝学 / Gene-modified rat / Epilepsy gene / Chlorambucil / Disease model / Etyl nitrosourea / Mutagenesis / Epilepsy / Rat / てんかん遺伝子 / クロラムブチル / エチルニトロソウレア / ミュータジェネシス / 熱性痙攣 / 炎症 / 熱性けいれん / けいれん重積 / 急性脳症 / 低線量 / ノックアウト / 動脈硬化 / TALENs / 人工ヌクレアーゼ / 遺伝子改変 / 上皮間葉化現象 / 高血圧自然発症ラット / ジンクフィンガーヌクレアーゼ / 補体 / 人工知能 / モデル動物 / 病態 / バイオリソース / マウス / 疾患 / データベース / CACNA1A / SCN1A / パッチクランプ / 難治 / チャネル / 小児神経学 / BACクローン / 遺伝解析 / コンジェニック系統 / NER / 原因遺伝子 Less

Development of novel gene editing methods based on the elucidation of the Type I CRISPR genome editing mechanismsPrincipal Investigator
- Principal Investigator
  
  真下知士
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
人はなぜ老い・病(やまい)になるのか－環境ストレス病態相関の理解
- Principal Investigator
  
  荻朋男
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Nagoya University
Fuchs角膜内皮変性症に対するゲノム医療の開発
- Principal Investigator
  
  宮井尊史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  The University of Tokyo
先端モデル動物支援プラットフォーム
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
Molecular pathogenesis of human disorders associated with deficiencies in the DNA repair and environmental stress response systems
- Principal Investigator
  
  OGI Tomoo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Nagoya University
Investigation of genetic etiology of rare diseases with craniofacial deformities
- Principal Investigator
  
  Kurosaka Hiroshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Osaka University
In vivo mass culture system of human iPS cell-derived hepatocytesPrincipal Investigator
- Principal Investigator
  
  Mashimo Tomoji
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokyo
  Osaka University
New development of genome editing technologies and disease modelsPrincipal Investigator
- Principal Investigator
  
  Mashimo Tomoji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  The University of Tokyo
  Osaka University
Molecular pathogenesis of human genetic disorders associated with deficiency in the DNA repair and damage response system
- Principal Investigator
  
  OGI Tomoo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Nagoya University
Comprehensive study for control of human papillomavirus-related oropharyngeal squamous cell carcinoma
- Principal Investigator
  
  Inohara Hidenori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Osaka University
Advanced Animal Model Support
- Principal Investigator
  
  INOUE Jun-ichiro, IMAI Kohzoh
- Principal Investigator(Support)
  
  IMAI Kohzoh
- Project Period (FY)
  2016 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
- Research Institution
  The University of Tokyo
Development of technologies for elucidating mechanisms how dynamic neural activities are generated by multiple inputs from other regions
- Principal Investigator
  
  OGAWA MASAAKI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Basic / Social brain science
- Research Institution
  Kyoto University
  National Institute for Physiological Sciences
Development of rat models as a component technology for visualizing the process of radiation-induced carcinogenesis
- Principal Investigator
  
  Imaoka Tatsuhiko
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Expansion of the informational technologies for mutual use of measurement data in biological science
- Principal Investigator
  
  MASUYA Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Intelligent informatics
- Research Institution
  Institute of Physical and Chemical Research
Significance of simultaneous secretion of insulin and incretin regulated by SKIP molecule
- Principal Investigator
  
  Harashima Shinichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
Development of genome editing technologies in laboratory ratsPrincipal Investigator
- Principal Investigator
  
  Mashimo Tomoji
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Osaka University
  Kyoto University
Establishment of a genetic rat model for combined hypertension and atherosclerosis using the genome editing technology.
- Principal Investigator
  
  NABIKA TORU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shimane University
Development of novel breast cancer model for understanding individual susceptibility to low dose radiation
- Principal Investigator
  
  Imaoka Tatsuhiko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institutes for Quantum and Radiological Science and Technology
Development of a animal model of acute encephalopathy and an antibody therapy
- Principal Investigator
  
  Ohmori Iori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
  Kyoto University
In vitro reconstitution of the initiation process of transcription-coupled nucleotide-excision repair
- Principal Investigator
  
  OGI Tomoo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Molecular biology
- Research Institution
  Nagoya University
  Nagasaki University
Study on the mechanism(s) of immunosenescence and its application for vaccine development.
- Principal Investigator
  
  HATTORI Masakazu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  Kyoto University
Role of complement 3 in the pathogenesis of hypertension
- Principal Investigator
  
  FUKUDA Noboru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Nihon University
Production of knockout rats using TALENs
- Principal Investigator
  
  KANEKO Takehito
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Development of fundamental technology for phenotype data integration in mouse and rat
- Principal Investigator
  
  MAUSUYA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  The Institute of Physical and Chemical Research
Genetic modifiers of an intractable epilepsy with channel gene mutations
- Principal Investigator
  
  OMORI Iori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Okayama University
Development of novel rat models for epilepsy and their molecular pathologic analysisPrincipal Investigator
- Principal Investigator
  
  MASHIMO Tomoji
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Elucidation of the genetic factors in rat epileptic seizures
- Principal Investigator
  
  SERIKAWA Tadao
- Project Period (FY)
  2008 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
ENUミュージェネシスにおける高速突然変異検出法Principal Investigator
- Principal Investigator
  
  真下知士
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
小脳性運動失調モデルマウスtambaleanteの原因遺伝子同定研究Principal Investigator
- Principal Investigator
  
  真下知士
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Development of rat models for human epilepsy by methods of gene modification
- Principal Investigator
  
  SERIKWA Tadao
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University

[Book] 真の実臨床応用をめざした再生医療20232023
- Author(s)
  渡辺祥司，吉見一人，真下知士
- Total Pages
  226
- Publisher
  羊土社
- ISBN
  9784758104081
- Data Source
  KAKENHI-PROJECT-18KK0307
[Book] 腫瘍内科2023
- Author(s)
  藤井智明、真下知士
- Total Pages
  123
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-18KK0307
[Book] Medical Science Digest　特集　遺伝子治療の最前線2022
- Author(s)
  藤井智明、真下知士
- Total Pages
  54
- Publisher
  ニューサイエンス社
- Data Source
  KAKENHI-PROJECT-18KK0307
[Book] 再生医療2022
- Author(s)
  吉見一人、真下知士
- Total Pages
  57
- Publisher
  日本再生医療学会雑誌
- Data Source
  KAKENHI-PROJECT-18KK0307
[Book] 研究年報第30集 2019 Annual Report of the Japan Epilepsy Research Foundation2019
- Author(s)
  大内田守, 真下知士, 豊國伸哉, 大守伊織
- Total Pages
  149
- Publisher
  公益財団法人てんかん治療研究振興財団
- Data Source
  KAKENHI-PROJECT-16H06276
[Book] 医療応用をめざすゲノム編集2018
- Author(s)
  真下　知士、金田　安史
- Total Pages
  274
- Publisher
  化学同人
- ISBN
  9784759817294
- Data Source
  KAKENHI-PROJECT-18H03974
[Book] 実験医学増刊号、All About ゲノム編集2016
- Author(s)
  真下知士、山本卓（監修）
- Total Pages
  234
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26290033
[Book] ゲノム編集入門－ZFN・TALEN・CRISPR-Cas9－2016
- Author(s)
  宮坂佳樹、真下知士
- Total Pages
  240
- Publisher
  裳華房
- Data Source
  KAKENHI-PROJECT-26290033
[Book] 創薬のひろば2016
- Author(s)
  真下知士
- Total Pages
  54
- Publisher
  エーイー企画
- Data Source
  KAKENHI-PROJECT-26290033
[Book] マウス表現型解析スタンダード、実験医学別冊2016
- Author(s)
  真下知士
- Total Pages
  351
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26290033
[Book] 論文だけではわからないゲノム編集成功の秘訣Q&A2015
- Author(s)
  真下知士
- Total Pages
  269
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-26290033
[Book] 進化するゲノム編集技術監修：真下知士、城石俊彦2015
- Author(s)
  真下知士
- Total Pages
  341
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-26290033
[Book] Engineered Nucleases Lead to Genome Editing Revolution in Rats. in Yamamoto T (eds): Targeted Genome Editing Using Site-Specific Nucleases2015
- Author(s)
  Yoshimi K, Kaneko T, Voigt B, Mashimo T
- Total Pages
  205
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-26290033
[Book] ジンクフィンガーヌクレアーゼ(ZFN)、細胞工学2012
- Author(s)
  真下知士、芹川忠夫
- Data Source
  KAKENHI-PROJECT-21680037
[Book] 生物機能モデルと新しいリソース・リサーチツール(モデル動物利用マニュアル):ジンクフィンガーヌクレアーゼ(ZFN)によるノックアウトラットの作製方法2011
- Author(s)
  真下知士
- Publisher
  LIC
- Data Source
  KAKENHI-PROJECT-21680037
[Book] ENU ミュータジェネシスによる標的遺伝子変異ラットの作製方法、生物機能モデルと新しいリソース・リサーチツール(モデル動物利用マニュアル)2011
- Author(s)
  真下知士
- Data Source
  KAKENHI-PROJECT-21680037
[Book] 生物機能モデルと新しいリソース・リサーチツール(モデル動物利用マニュアル):ENUミュータジェネシスによる標的遺伝子変異ラットの作製方法2010
- Author(s)
  真下知士
- Publisher
  LIC
- Data Source
  KAKENHI-PROJECT-21680037
[Book] ラット:多様なニーズに応える実験動物、バイオリソース&データベース活用術(細胞工学別冊)2009
- Author(s)
  真下知士、芹川忠夫
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-21680037
[Book] バイオリソース&データベース活用術(細胞工学別冊)2009
- Author(s)
  真下知士、芹川忠夫
- Total Pages
  3
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-21680037
[Book] 無敵のバイオテクニカルシリーズマウス・ラット実験ノート2009
- Author(s)
  真下知士
- Total Pages
  17
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] Brca2(p.T1942fs/+) dissipates ovarian reserve in rats through oxidative stress in follicular granulosa cells.2024
- Author(s)
  Tanaka H, Motooka Y, Maeda Y, Sonehara R, Nakamura T, Kajiyama H, Mashimo T, Toyokuni S.
- Journal Title
  
  Free Radic Res
  
  Volume: 58(2) Issue: 2 Pages: 130-143
- DOI
  10.1080/10715762.2024.2320405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23H00367
[Journal Article] Age-related ciliopathy: Obesogenic shortening of melanocortin-4 receptor-bearing neuronal primary cilia2024
- Author(s)
  Oya Manami、Miyasaka Yoshiki、Nakamura Yoshiko、Tanaka Miyako、Suganami Takayoshi、Mashimo Tomoji、Nakamura Kazuhiro
- Journal Title
  
  Cell Metabolism
  
  Volume: 36 Issue: 5 Pages: 1044-1058
- DOI
  10.1016/j.cmet.2024.02.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15343, KAKENHI-PROJECT-21K06767, KAKENHI-PROJECT-21K08526, KAKENHI-PROJECT-20H03418, KAKENHI-PUBLICLY-23H04776, KAKENHI-PROJECT-22H04922
[Journal Article] ゲノム編集技術のオーバービューおよび医療応用をめぐる国内外の動向2024
- Author(s)
  真下　知士
- Journal Title
  
  実験医学
  
  Volume: Vol.42 No.6 Pages: 870-875
- Data Source
  KAKENHI-PROJECT-23H00367
[Journal Article] A novel Kit mutant rat enables hematopoietic stem cell engraftment without irradiation2024
- Author(s)
  Iida Ryuya、Ishida Saeko、Wang Jinxi、Hattori Kosuke、Yoshimi Kazuto、Yamazaki Satoshi、Mashimo Tomoji
- Journal Title
  
  Experimental Hematology
  
  Volume: 132 Pages: 104174-104174
- DOI
  10.1016/j.exphem.2024.104174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19238, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-21K05987, KAKENHI-PROJECT-23H00367
[Journal Article] A missense mutation in the Hspa8 gene encoding heat shock cognate protein 70 causes neuroaxonal dystrophy in rats2024
- Author(s)
  Tanaka M, Fujikawa R, Sekiguchi T, Johnson OT, Tanaka D, Kumafuji K, Serikawa T, Trung HH, Hattori K, Mashimo T, Kuwamura M, Gestwicki JE, Kuramoto T
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 18 Pages: 0-0
- DOI
  10.3389/fnins.2024.1263724
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-23H00367
[Journal Article] ゲノム編集ラットの作製と遺伝子治療研究への応用2023
- Author(s)
  吉見一人, 真下　知士
- Journal Title
  
  遺伝子治療開発研究ハンドブック
  
  Volume: 第2版 Pages: 100-104
- Data Source
  KAKENHI-PROJECT-23H00367
[Journal Article] Protocol for highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence in rodents2023
- Author(s)
  Matsushita Natsuki、Kato Shigeki、Nishizawa Kayo、Sugawara Masateru、Takeuchi Kosei、Miyasaka Yoshiki、Mashimo Tomoji、Kobayashi Kazuto
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 4 Pages: 102667-102667
- DOI
  10.1016/j.xpro.2023.102667
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PROJECT-22K20687, KAKENHI-PUBLICLY-22H04786, KAKENHI-PROJECT-23H00367
[Journal Article] BRCA1 haploinsufficiency impairs iron metabolism to promote chrysotile‐induced mesothelioma via ferroptosis resistance2023
- Author(s)
  Luo Yaguang、Akatsuka Shinya、Motooka Yashiro、Kong Yingyi、Zheng Hao、Mashimo Tomoji、Imaoka Tatsuhiko、Toyokuni Shinya
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 4 Pages: 1423-1436
- DOI
  10.1111/cas.15705
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07588, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-23K21752, KAKENHI-PROJECT-23H00367
[Journal Article] The rat Downunder (Du) coat color mutation is associated with eye anomalies and embryonic lethality and maps to a 3.9-Mb region on chromosome 32023
- Author(s)
 Hieu Hoang Trung、Tanaka Miyuu、Kuwamura Mitsuru、Mashimo Tomoji、Serikawa Tadao、Kuramoto Takashi
- Journal Title
 
 Exp. Anim.
 
 Volume: 72 Issue: 1 Pages: 88-94
- DOI
 10.1538/expanim.22-0086
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-18KK0307
[Journal Article] Developmental changes in brain activity of heterozygous Scn1a knockout rats2023
- Author(s)
  Tahara Mayu、Higurashi Norimichi、Hata Junichi、Nishikawa Masako、Ito Ken、Hirose Shinichi、Kaneko Takehito、Mashimo Tomoji、Sakuma Tetsushi、Yamamoto Takashi、Okano Hirotaka James
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 14 Pages: 1125089-1125089
- DOI
  10.3389/fneur.2023.1125089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06137, KAKENHI-PROJECT-21K07780, KAKENHI-PROJECT-18KK0307
[Journal Article] ゲノム編集技術の応用2023
- Author(s)
  石田紗恵子、真下　知士
- Journal Title
  
  医学のあゆみ「mRNAワクチンやゲノム編集で注目が集まる遺伝子治療」
  
  Volume: Vol.285(5) Pages: 328-333
- Data Source
  KAKENHI-PROJECT-23H00367
[Journal Article] Txn1 mutation is a monogenic cause of chronic kidney disease associated with mitochondrial dysfunction in rats2023
- Author(s)
  Ohmori I, Ouchida M, Hada Y, Uchida HA, Toyokuni S, Mashimo T.
- Journal Title
  
  BioRxiv
  
  Volume: -
- DOI
  10.1101/2023.08.14.553187
- Open Access
- Data Source
  KAKENHI-PROJECT-22H04922
[Journal Article] Remnant tissue enhances early postoperative biomechanical strength and infiltration of Scleraxis-positive cells within the grafted tendon in a rat anterior cruciate ligament reconstruction model2023
- Author(s)
  Kawakami Junki, Hisanaga Satoshi ,Yoshimoto Yuki (他11名) Okamoto Nobukazu、Masuda Tetsuro、Miyamoto Takeshi
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 11 Pages: 0293944-0293944
- DOI
  10.1371/journal.pone.0293944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09242, KAKENHI-PROJECT-22K09427, KAKENHI-PROJECT-23K08614, KAKENHI-PROJECT-23H00367, KAKENHI-PROJECT-21H03057
[Journal Article] In vivo18F-DOPA PET imaging identifies a dopaminergic deficit in a rat model with a G51D α-synuclein mutation2023
- Author(s)
  Morley Victoria、Dolt Karamjit Singh、Alcaide-Corral Carlos J.、Walton Tashfeen、Lucatelli Christophe、Mashimo Tomoji、Tavares Adriana A. S.、Kunath Tilo
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 17 Pages: 0-0
- DOI
  10.3389/fnins.2023.1095761
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00367
[Journal Article] CRISPR-Casシステム―ゲノム編集と医療への応用2023
- Author(s)
  吉見一人, 真下　知士
- Journal Title
  
  日本医師会雑誌
  
  Volume: 第152巻・特別号（１） Pages: 194-197
- Data Source
  KAKENHI-PROJECT-23H00367
[Journal Article] A senolytic immunotoxin eliminates p16-positive T cells and ameliorates age-associated phenotypes of CD4+ T cells in a surface marker knock-in mouse2023
- Author(s)
  Sugiyama Yuma、Harada Tanenobu、Kamei Yuka、Yasuda Tomoharu、Mashimo Tomoji、Nishikimi Akihiko、Maruyama Mitsuo
- Journal Title
  
  Experimental Gerontology
  
  Volume: 174 Pages: 112130-112130
- DOI
  10.1016/j.exger.2023.112130
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17820, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-23K24781, KAKENHI-PROJECT-21H02751
[Journal Article] Imbalance of glutamatergic and GABAergic neurotransmission in audiogenic seizure-susceptible L?eucine-rich glioma-inactivated 1?(Lgi1)-mutant rats2023
- Author(s)
  Masato Kinboshi, Saki Shimizu, Kentaro Tokudome, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Ryosuke Takahashi, Akio Ikeda, Yukihiro Ohno
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 7 Pages: e17984-e17984
- DOI
  10.1016/j.heliyon.2023.e17984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21573, KAKENHI-PROJECT-23H00367
[Journal Article] Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner2023
- Author(s)
 MORI Masayuki、DAI Jian、MIYAHARA Hiroki、LI Ying、KANG Xiaojing、YOSHIMI Kazuto、MASHIMO Tomoji、HIGUCHI Keiichi、MATSUMOTO Kiyoshi
- Journal Title
 
 Exp. Anim.
 
 Volume: 72 Issue: 2 Pages: 233-241
- DOI
 10.1538/expanim.22-0122
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-22K19238, KAKENHI-PROJECT-19KK0401
[Journal Article] 2. Highly selective transgene expression through the flip-excision switch system by using a unilateral spacer sequence.2023
- Author(s)
  Matsushita, N.*, Kato, S.*, Nishizawa, K., Sugawara, M., Takeuchi, K., Miyasaka, Y., Mashimo, T. and Kobayashi, K. * Equal contribution
- Journal Title
  
  Cell Rep. Methods
  
  Volume: 3 Issue: 2 Pages: 100393-100393
- DOI
  10.1016/j.crmeth.2022.100393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PLANNED-21H05244, KAKENHI-PROJECT-21H02817, KAKENHI-PROJECT-19K16264, KAKENHI-PROJECT-18KK0307, KAKENHI-ORGANIZER-21H05238, KAKENHI-PUBLICLY-21H00442, KAKENHI-PROJECT-22K20687, KAKENHI-PROJECT-22K19590, KAKENHI-PUBLICLY-22H04786
[Journal Article] Hydrogen sulfide and polysulfides induce GABA/glutamate/d-serine release, facilitate hippocampal LTP, and regulate behavioral hyperactivity2023
- Author(s)
  Hiroki Furuie#、Yuka Kimura#、Tatsuhiro Akaishi#、Misa Yamada、Yoshiki Miyasaka、Akiyoshi Saitoh、Norihiro Shibuya、Akiko Watanabe、Naoki Kusunose、Tomoji Mashimo、Takeo Yoshikawa、Mitsuhiko Yamada、Kazuho Abe、Hideo Kimura
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-19
- DOI
  10.1038/s41598-023-44877-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11814, KAKENHI-PROJECT-23K06016, KAKENHI-PROJECT-19K06554, KAKENHI-PROJECT-21K03136, KAKENHI-PROJECT-23H00367
[Journal Article] Brca1^L63X/+ rat is a novel model of human BRCA1 deficiency displaying susceptibility to radiation-induced mammary cancer2022
- Author(s)
  Yuzuki Nakamura, Jo Kubota, Yukiko Nishimura, Kento Nagata, Mayumi Nishimura, Kazuhiro Daino, Atsuko Ishikawa, Takehito Kaneko, Tomoji Mashimo, Toshiaki Kokubo, Masaru Takabatake, Kazumasa Inoue, Masahiro F
- Journal Title
  
  Cancer science
  
  Volume: 113 Issue: 10 Pages: 3362-3375
- DOI
  10.1111/cas.15485
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04932, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-23K21752
[Journal Article] A high-quality severe combined immunodeficiency (SCID) rat bioresource.2022
- Author(s)
  Yoshiki Miyasaka, Jinxi Wang, Kosuke Hattori, Yuko Yamauchi, Miho Hoshi, Kazuto Yoshimi, Saeko Ishida, Tomoji Mashimo,
- Journal Title
  
  PloS one
  
  Volume: 17 Issue: 8 Pages: e0272950-e0272950
- DOI
  10.1371/journal.pone.0272950
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19238, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-18KK0307
[Journal Article] 受精卵のゲノム編集2022
- Author(s)
  石田紗恵子、真下知士
- Journal Title
  
  HORMONE FRONTIER IN GYNECOLOGY
  
  Volume: Vol.29 No.1 Pages: 31-36
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] Filaggrin-deficient rats generated using zinc-finger nucleases spontaneously exhibit dry scaly skin2022
- Author(s)
  Nakashima Chisa、Doi Hiromi、Nakajima Saeko、Mashimo Tomoji、Oga Toru、Ishida-Yamamoto Akemi、Honda Tetsuya、Ishida Yoshihiro、Otsuka Atsushi、Kabashima Kenji
- Journal Title
  
  Allergol. Int.
  
  Volume: 71 Issue: 4 Pages: 545-547
- DOI
  10.1016/j.alit.2022.04.001
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K16210, KAKENHI-PROJECT-20K08689, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-20H05697
[Journal Article] Novel animal model of combined generalized and focal epilepsy.2022
- Author(s)
  Ohmori I, Ouchida M, Shinohara M, Kobayashi K, Ishida S, Mashimo T.
- Journal Title
  
  Epilepsia
  
  Volume: 63 Issue: 7
- DOI
  10.1111/epi.17295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07914, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18KK0307
[Journal Article] CRISPR-mediated Bmpr2 point mutation exacerbates late pulmonary vasculopathy and reduces survival in rats with experimental pulmonary hypertension2022
- Author(s)
  Kabwe JC, Sawada H, Mitani Y, Oshita H, Tsuboya N, Zhang E, Maruyama J, Miyasaka Y, Ko H, Oya K, Ito H, Yodoya N, Otsuki S, Ohashi H, Okamoto R, Dohi K, Nishimura Y, Mashimo T, Hirayama M, Maruyama K.
- Journal Title
  
  Respir Res.
  
  Volume: ;23 Issue: 1 Pages: 1-22
- DOI
  10.1186/s12931-022-02005-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08192, KAKENHI-PROJECT-22K07843, KAKENHI-PROJECT-22K08098, KAKENHI-PROJECT-19K08578, KAKENHI-PROJECT-20K08565, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-21K07817
[Journal Article] Thioredoxin deficiency increases oxidative stress and causes bilateral symmetrical degeneration in rat midbrain2022
- Author(s)
  Ohmori I, Ouchida M, Imai H, Ishida S, Toyokuni S, Mashimo T.
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 175 Pages: 105921-105921
- DOI
  10.1016/j.nbd.2022.105921
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18KK0307
[Journal Article] Dynamic mechanisms of CRISPR interference by Escherichia coli CRISPR-Cas32022
- Author(s)
  Yoshimi Kazuto、Takeshita Kohei、Kodera Noriyuki、Shibumura Satomi、Yamauchi Yuko、Omatsu Mine、Umeda Kenichi、Kunihiro Yayoi、Yamamoto Masaki、Mashimo Tomoji
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 4917-4917
- DOI
  10.1038/s41467-022-32618-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K04849, KAKENHI-PROJECT-22K19238, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-23K23533
[Journal Article] A heterozygous LAMA5 variant may contribute to slowly progressive, vinculin-enhanced familial FSGS and pulmonary defects.2022
- Author(s)
  Kaimori JY, Kikkawa Y, Motooka D, Namba-Hamano T, Takuwa A, Okazaki A, Kobayashi K, Tanigawa A, Kotani Y, Uno Y, Yoshimi K, Hattori K, Asahina Y, Kajimoto S, Doi Y, Oka T, Sakaguchi Y, Mashimo T, Sekiguchi K, Nakaya A, Nomizu M, Isaka Y.
- Journal Title
  
  JCI insight
  
  Volume: 7 Issue: 23 Pages: 522-524
- DOI
  10.1172/jci.insight.158378
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19238, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-19K06629, KAKENHI-PROJECT-20K07622, KAKENHI-PROJECT-18KK0307
[Journal Article] 受精卵のゲノム編集2022
- Author(s)
  石田紗恵子、真下知士
- Journal Title
  
  HORMONE FRONTIER IN GYNECOLOGY
  
  Volume: Vol.29 No.1 Pages: 31-36
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] 3. Catecholaminergic cell type-specific expression of Cre recombinase in knock-in transgenic rats generated by the Combi-CRISPR technology.2022
- Author(s)
  Matsushita, N., Nishizawa, K., Kato, S., Iguchi, Y., Fukabori, R., Takeuchi, K., Miyasaka, Y., Mashimo, T. and Kobayashi, K.
- Journal Title
  
  J. Neurosci. Methods
  
  Volume: 381 Pages: 109707-109707
- DOI
  10.1016/j.jneumeth.2022.109707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06912, KAKENHI-PROJECT-22K20687, KAKENHI-PLANNED-21H05244, KAKENHI-PROJECT-21H02817, KAKENHI-PROJECT-19K16264, KAKENHI-PROJECT-18KK0307, KAKENHI-ORGANIZER-21H05238, KAKENHI-PUBLICLY-21H00442, KAKENHI-PROJECT-22K19590
[Journal Article] A humanised rat model of osteosarcoma reveals ultrastructural differences between bone and mineralised tumour tissue2022
- Author(s)
  Lahr Christoph A.、Landgraf Marietta、Wagner Ferdinand、Cipitria Amaia、Moreno-Jimenez Ines、Bas Onur、Schmutz Beat、Meinert Christoph、Cavalcanti Amanda Dos Santos、Mashimo Tomoji、Miyasaka Yoshiki、Holzapfel Boris M.、Shafiee Abbas、McGovern Jacqui A.、Hutmacher Dietmar W.
- Journal Title
  
  Bone
  
  Volume: 158 Pages: 116018-116018
- DOI
  10.1016/j.bone.2021.116018
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18KK0307
[Journal Article] Impact of GAD65 and/or GAD67 deficiency on perinatal development in rats.2022
- Author(s)
  Jiang W, Kakizaki T, Fujihara K, Miyata S, Zhang Y, Suto T, Kato D, Saito S, Shibasaki K, Ishizaki Y, Isoda K, Yokoo H, Obinata H, Hirano T, Miyasaka Y, Mashimo T, Yanagawa Y.
- Journal Title
  
  .FASEB J .
  
  Volume: 36(2) Issue: 2
- DOI
  10.1096/fj.202101389r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17628, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-19K06881, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-22K06434, KAKENHI-PUBLICLY-21H05632
[Journal Article] BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance2022
- Author(s)
  Kong Yingyi、Akatsuka Shinya、Motooka Yashiro、Zheng Hao、Cheng Zhen、Shiraki Yukihiro、Mashimo Tomoji、Imaoka Tatsuhiko、Toyokuni Shinya
- Journal Title
  
  Redox Biology
  
  Volume: 54 Pages: 102356-102356
- DOI
  10.1016/j.redox.2022.102356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07588, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-23K21752
[Journal Article] Study of the CRISPR/Cas3 System for Xenotransplantation2022
- Author(s)
  Miyagawa S, Watanabe M, Nagashima H, Sato K, Kogata S, Toyama C, Masahata K, Kamiyama M, Yamamoto R, Eguchi H, Maeda A, Yoshimi K, Mashimo T, Okuyama H.
- Journal Title
  
  Transplant Proc
  
  Volume: 54 Issue: 2 Pages: 522-524
- DOI
  10.1016/j.transproceed.2021.09.070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-21K19527, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-18KK0307
[Journal Article] CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus2022
- Author(s)
  Yoshimi K, Takeshita K, Yamayoshi S, Shibumura S, Yamauchi Y, Yamamoto M, Yotsuyanagi H, Kawaoka Y, Mashimo T.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 2 Pages: 103830-103830
- DOI
  10.1016/j.isci.2022.103830
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-23K23533
[Journal Article] Response to correspondence on “Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation”2021
- Author(s)
  Gurumurthy Channabasavaiah B.、O’Brien Aidan R.、・・・・・・・・・・・・・・・・・・Mashimo Tomoji、・・・・・・・・・・・・・・・Burgio Gaetan
- Journal Title
  
  Genome Biology
  
  Volume: 22 Issue: 1
- DOI
  10.1186/s13059-021-02320-3
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18KK0307
[Journal Article] Genetic Deletion of Glutamate Decarboxylase 67-kDa Isoform Alters Conditioned Fear Behavior in Rats.2021
- Author(s)
  Fujihara K, Sato T, Miyasaka Y, Mashimo T, Yanagawa Y.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 11 Issue: 2 Pages: 340-353
- DOI
  10.1002/2211-5463.13065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06881, KAKENHI-PROJECT-17K17628, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-16H06276
[Journal Article] Behavioral consequences of a combination of Gad1 haplodeficiency and adolescent exposure to NMDA receptor antagonist in Long-Evans rat.2021
- Author(s)
  Fujihara K, Sato T, Higeta K, Miyasaka Y, Mashimo T, Yanagawa Y.
- Journal Title
  
  Front Pharmacol.
  
  Volume: 12 Pages: 646088-646088
- DOI
  10.3389/fphar.2021.646088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06881, KAKENHI-PROJECT-17K17628, KAKENHI-PROJECT-16H06276
[Journal Article] Aberrant accumulation of TMEM43 accompanied by perturbed transmural gene expression in arrhythmogenic cardiomyopathy2021
- Author(s)
  Shinomiya Haruki、Kato Hisakazu、・・・・・・・・Mashimo Tomoji、・・・・・・・・・・・・・・・・Sakata Yasushi、Asano Yoshihiro
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 11
- DOI
  10.1096/fj.202100800r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-19H03652
[Journal Article] Deletion of B-cell translocation gene 2 (BTG2) alters the responses of glial cells in white matter to chronic cerebral hypoperfusion2021
- Author(s)
  Suzuki Kaoru、Shinohara Mitsuru、Uno Yoshihiro、Tashiro Yoshitaka、Gheni Ghupurjan、Yamamoto Miho、Fukumori Akio、Shindo Akihiko、Mashimo Tomoji、Tomimoto Hidekazu、Sato Naoyuki
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 18 Issue: 1
- DOI
  10.1186/s12974-021-02135-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] CRISPR技術を用いた核酸検出2021
- Author(s)
  吉見一人、真下知士
- Journal Title
  
  実験医学
  
  Volume: 2021年5月号 Vol.39 No.8 Pages: 1214-1218
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Txnl mutation causes epilepsy associated with vacuolar degeneration in the midbrain2021
- Author(s)
  Iori Ohmori, Mamoru Ouchida, Hirohiko Imai, Saeko Ishida, Shinya Toyokuni, Tomoji Mashimo
- Journal Title
  
  bioRxiv
- DOI
  10.1101/2021.10.07.463470
- Open Access
- Data Source
  KAKENHI-PROJECT-16H06276
[Journal Article] PHF24 is expressed in the inhibitory interneurons in rats2021
- Author(s)
  Numakura Yuki、Uemura Risa、Tanaka Miyuu、Izawa Takeshi、Yamate Jyoji、Kuramoto Takashi、Kaneko Takehito、Mashimo Tomoji、Yamamoto Takashi、Serikawa Tadao、Kuwamura Mitsuru
- Journal Title
  
  Exp. Anim.
  
  Volume: 70 Issue: 1 Pages: 137-143
- DOI
  10.1538/expanim.20-0105
- NAID
  130007981760
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974
[Journal Article] Combi-CRISPR: combination of NHEJ and HDR provides efficient and precise plasmid-based knock-ins in mice and rats2020
- Author(s)
  Yoshimi K, Oka Y, Miyasaka Y, Kotani Y, Yasumura M, Uno Y, Hattori K, Tanigawa A, Sato M, Oya M, Nakamura K, Matsushita N, Kobayashi K, Mashimo T
- Journal Title
  
  Hum Genet
  
  Volume: 140 Issue: 2 Pages: 277-287
- DOI
  10.1007/s00439-020-02198-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06923, KAKENHI-PROJECT-19K22474, KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-20J40056, KAKENHI-PROJECT-19K22471, KAKENHI-PROJECT-17K15571, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-20H03414, KAKENHI-PROJECT-21K06409, KAKENHI-PROJECT-20H03418
[Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020
- Author(s)
  Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 8 Issue: 1 Pages: 206-206
- DOI
  10.1186/s40478-020-01082-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06886, KAKENHI-PROJECT-18KK0307, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17K07063, KAKENHI-PROJECT-17K07126, KAKENHI-PROJECT-18K07577, KAKENHI-PLANNED-16H06528, KAKENHI-PLANNED-16H06532, KAKENHI-PROJECT-18H02538
[Journal Article] Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome2020
- Author(s)
  Oka Y, Hamada M, Nakazawa Y, ..., Tanaka M, Suganami T, Nakada S, Mitsutake N, Hara Y, Kato K, ..., Kaneko H, Matsumoto N, Matsuda F, Matsuo K, Takahashi Y, Mashimo T, Kojima S, Ogi T
- Journal Title
  
  Science Advances
  
  Volume: 6 Issue: 51 Pages: 7197-7197
- DOI
  10.1126/sciadv.abd7197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21718, KAKENHI-PROJECT-20KK0217, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K08508, KAKENHI-PROJECT-18K19585, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-20H03447, KAKENHI-PROJECT-20H00629
[Journal Article] ゲノム編集医療－技術開発・治療応用戦略を中心に、特集コーディネーター2020
- Author(s)
  真下知士・吉見一人
- Journal Title
  
  遺伝子医学
  
  Volume: 第10巻第4号（通巻34号） Pages: 1-176
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] Aspects of Gene Therapy Products Using Current Genome-Editing Technology in Japan2020
- Author(s)
  Yamaguchi Teruhide、Uchida Eriko、Okada Takashi、Ozawa Keiya、Onodera Masafumi、Kume Akihiro、Shimada Takashi、Takahashi Satoru、Tani Kenzaburo、Nasu Yasutomo、Mashimo Tomoji、Mizuguchi Hiroyuki、Mitani Kohnosuke、Maki Kazushige
- Journal Title
  
  Human Gene Therapy
  
  Volume: 31 Issue: 19-20 Pages: 1043-1053
- DOI
  10.1089/hum.2020.156
- NAID
  120007147867
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K07853, KAKENHI-PROJECT-23K20328
[Journal Article] Pathophysiological significance of Stim1 mutation in sympathetic response to stress and cardiovascular phenotypes in SHRSP/Izm: In vivo evaluation by creation of a novel gene knock-in rat using CRISPR/Cas92020
- Author(s)
  Odongoo Batbayar、Ohara Hiroki、Ngarashi Davis、Kaneko Takehito、Kunihiro Yayoi、Mashimo Tomoji、Nabika Toru
- Journal Title
  
  Clinical and Experimental Hypertension
  
  Volume: 43 Issue: 1 Pages: 34-41
- DOI
  10.1080/10641963.2020.1797085
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974
[Journal Article] 効率的なゲノム編集ラットの作製方法2020
- Author(s)
  服部晃佑、吉見一人、松下夏樹、小林和人、真下知士
- Journal Title
  
  マウス・ラットモデル作製・解析プロフェッショナル. あなたの研究をステップアップさせる最新・最適手技. 先端モデル動物支援プラットフォーム（AdAMS）
  
  Volume: - Pages: 54-63
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] 高血圧関連疾患モデル動物作製の現状と展望2020
- Author(s)
  山内祐子、真下知士
- Journal Title
  
  日本臨牀増刊号「高血圧学（上）
  
  Volume: 78巻 Pages: 379-384
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] Photoactivatable Cre knock-in mice for spatiotemporal control of genetic engineering in vivo2020
- Author(s)
  Yoshimi Kazuto、Yamauchi Yuko、Tanaka Takao、Shimada Toshio、Sato Moritoshi、Mashimo Tomoji
- Journal Title
  
  Laboratory Investigation
  
  Volume: 101 Issue: 1 Pages: 125-135
- DOI
  10.1038/s41374-020-00482-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-19KK0401, KAKENHI-PROJECT-18H03974
[Journal Article] Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus2020
- Author(s)
 Konishi S, Tanaka N, Mashimo T, Yamamoto T, Sakuma T, Kaneko T, Tanaka M, Izawa T, Yamate J, Kuwamura M
- Journal Title
 
 Exp. Anim.
 
 Volume: 69 Issue: 1 Pages: 26-33
- DOI
 10.1538/expanim.19-0005
- NAID
 130007791587
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-19K16111, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974
[Journal Article] 効率的なゲノム編集ラットの作製方法2020
- Author(s)
  服部晃佑、吉見一人、松下夏樹、小林和人、真下知士
- Journal Title
  
  マウス・ラットモデル作製・解析プロフェッショナル. あなたの研究をステップアップさせる最新・最適手技. 先端モデル動物支援プラットフォーム（AdAMS）
  
  Volume: - Pages: 54-63
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] ゲノム編集技術を用いた遺伝子改変ラットの作製2020
- Author(s)
  宮坂佳樹、真下知士
- Journal Title
  
  医学のあゆみ「ゲノム編集の未来」
  
  Volume: Vol.273(9) Pages: 785-794
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair2020
- Author(s)
  Nakazawa Y, Hara Y, Oka Y, Komine O, van den Heuvel D, Guo C, Daigaku Y, Isono M, He Y, Shimada M, Kato K, Jia N, Hashimoto S, Kotani Y, Miyoshi Y, Tanaka M, Sobue A, Mitsutake N, Suganami T, Masuda A, Ohno K, Nakada S, Mashimo T, Yamanaka K, Luijsterburg MS, Ogi T
- Journal Title
  
  Cell
  
  Volume: 19 Issue: 6 Pages: 1228-1244
- DOI
  10.1016/j.cell.2020.02.010
- NAID
  120006871293
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-18K08508, KAKENHI-PROJECT-18K11639, KAKENHI-PROJECT-18K19585, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17H01877, KAKENHI-PROJECT-18H03372, KAKENHI-PROJECT-16H06151, KAKENHI-PROJECT-17K12821, KAKENHI-PROJECT-19K21221
[Journal Article] ゲノム編集技術CRISPR-Cas3とその遺伝子治療および診断への応用2020
- Author(s)
  藤井智明、吉見一人、真下知士
- Journal Title
  
  実験医学（増刊）新規の創薬モダリティ　細胞医療
  
  Volume: Vol.38, No.17 Pages: 49-54
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Assembly and Function of a Bioengineered Human Liver for Transplantation Generated Solely from Induced Pluripotent Stem Cells2020
- Author(s)
  Takeishi Kazuki、Collin de l’Hortet Alexandra、Wang Yang、Handa Kan、Mashimo Tomoji、Fox Ira J.、Soto-Gutierrez Alejandro
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 9 Pages: 107711-107711
- DOI
  10.1016/j.celrep.2020.107711
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K08701
[Journal Article] 新規ゲノム編集ツールCRISPR-Cas32020
- Author(s)
  真下　知士、吉見　一人
- Journal Title
  
  Precision Medicine
  
  Volume: 3(6) Pages: 512-515
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Generation of knockout rabbits with X-linked severe combined immunodeficiency (X-SCID) using CRISPR/Cas92020
- Author(s)
  Hashikawa Yoshiko、Hayashi Ryuhei、Tajima Masaru、Okubo Toru、Azuma Shohei、Kuwamura Mitsuru、Takai Naofumi、Osada Yasuyuki、Kunihiro Yayoi、Mashimo Tomoji、Nishida Kohji
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 9957-9957
- DOI
  10.1038/s41598-020-66780-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-20H03842, KAKENHI-PROJECT-19H01063
[Journal Article] CRISPR/Cas9-engineered Gad1 elimination in rats leads to complex behavioral changes: implications for schizophrenia2020
- Author(s)
  Fujihara Kazuyuki、Yamada Kazuo、Ichitani Yukio、Kakizaki Toshikazu、Jiang Weiru、Miyata Shigeo、Suto Takashi、Kato Daiki、Saito Shigeru、Watanabe Masahiko、Kajita Yuki、Ohshiro Tomokazu、Mushiake Hajime、Miyasaka Yoshiki、Mashimo Tomoji、Yasuda Hiroki、Yanagawa Yuchio
- Journal Title
  
  Translational Psychiatry
  
  Volume: 10 Issue: 1 Pages: 426-426
- DOI
  10.1038/s41398-020-01108-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06516, KAKENHI-PROJECT-19K03365, KAKENHI-PROJECT-19K06881, KAKENHI-PROJECT-19K22464, KAKENHI-PROJECT-17K17628, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-16H06276
[Journal Article] CRISPR-Cas3を用いた新しいゲノム編集2020
- Author(s)
  吉見一人、真下知士
- Journal Title
  
  医学のあゆみ「ゲノム編集の未来」
  
  Volume: Vol.273(9) Pages: 751-755
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] ゲノム編集医療－技術開発・治療応用戦略を中心に、特集コーディネーター2020
- Author(s)
  真下　知士、吉見　一人
- Journal Title
  
  遺伝子医学
  
  Volume: 第10巻第4号（通巻34号） Pages: 1-176
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] ゲノム編集技術を用いた遺伝子改変ラットの作製2020
- Author(s)
  宮坂佳樹、真下知士
- Journal Title
  
  医学のあゆみ「ゲノム編集の未来」
  
  Volume: Vol.273(9) Pages: 785-794
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] 高血圧関連疾患モデル動物作製の現状と展望2020
- Author(s)
  山内祐子、真下知士
- Journal Title
  
  日本臨牀増刊号「高血圧学（上）」
  
  Volume: 78巻 Pages: 379-384
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Effects of the Prdx2 depletion on blood pressure and life span in spontaneously hypertensive rats2019
- Author(s)
  Mahal Zinat、Fujikawa Koichi、Matsuo Hiroyuki、Zahid Hasan M.、Koike Masamichi、Misumi Masaki、Kaneko Takehito、Mashimo Tomoji、Ohara Hiroki、Nabika Toru
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 5 Pages: 610-617
- DOI
  10.1038/s41440-019-0207-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] CRISPR-Cas3 induces broad and unidirectional genome editing in human cells2019
- Author(s)
  Morisaka Hiroyuki、Yoshimi Kazuto、Okuzaki Yuya、Gee Peter、Kunihiro Yayoi、Sonpho Ekasit、Xu Huaigeng、Sasakawa Noriko、Naito Yuki、Nakada Shinichiro、Yamamoto Takashi、Sano Shigetoshi、Hotta Akitsu、Takeda Junji、Mashimo Tomoji
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 5302-5302
- DOI
  10.1038/s41467-019-13226-x
- NAID
  120006848247
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16025, KAKENHI-PROJECT-17H01409, KAKENHI-PROJECT-18H03974
[Journal Article] Null mutation of the endothelin receptor type B gene causes embryonic death in the GK rat2019
- Author(s)
  Wang Jinxi、Dang Ruihua、Miyasaka Yoshiki、Hattori Kousuke、Torigoe Daisuke、Okamura Tadashi、Tag-EI-Din-Hassan Hassan T.、Morimatsu Masami、Mashimo Tomoji、Agui Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 6 Pages: e0217132-e0217132
- DOI
  10.1371/journal.pone.0217132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974
[Journal Article] 疾患モデルラットの国内外トレンド2019
- Author(s)
  真下知士
- Journal Title
  
  実験動物技術
  
  Volume: 54 Pages: 91-95
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] 免疫不全ラットの開発と利用2019
- Author(s)
  15.山内祐子、吉見一人、真下知士
- Journal Title
  
  LABIO21実験動物としてのラットの有用性
  
  Volume: 78 Pages: 16-19
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] ゲノム編集技術によるモデル動物の作製2019
- Author(s)
  真下知士
- Journal Title
  
  メディカル・サイエンス・ダイジェスト
  
  Volume: 45 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] ラット受精卵でのゲノム編集2019
- Author(s)
  吉見一人、真下知士
- Journal Title
  
  実験医学別冊　ゲノム編集実験スタンダード
  
  Volume: X
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver2019
- Author(s)
  Ueda Tomoaki、Yokota Takafumi、Okuzaki Daisuke、Uno Yoshihiro、Mashimo Tomoji、Kubota Yoshiaki、Sudo Takao、Ishibashi Tomohiko、Shingai Yasuhiro、Doi Yukiko、Ozawa Takayuki、Nakai Ritsuko、Tanimura Akira、Ichii Michiko、Ezoe Sachiko、Shibayama Hirohiko、Oritani Kenji、Kanakura Yuzuru
- Journal Title
  
  Stem Cell Reports
  
  Volume: 13 Issue: 6 Pages: 992-1005
- DOI
  10.1016/j.stemcr.2019.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08355, KAKENHI-PROJECT-19K08861, KAKENHI-PROJECT-19K08863, KAKENHI-PROJECT-19K17622, KAKENHI-PROJECT-18KK0307, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-18K16114
[Journal Article] 疾患モデルラットの国内外トレンド2019
- Author(s)
  真下知士
- Journal Title
  
  実験動物技術
  
  Volume: 54 Pages: 91-95
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] ゲノム編集技術によるモデル動物の作製2019
- Author(s)
  真下知士
- Journal Title
  
  メディカル・サイエンス・ダイジェスト
  
  Volume: 45 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] 免疫不全ラットの開発と利用2019
- Author(s)
  山内祐子、吉見一人、真下知士
- Journal Title
  
  LABIO21実験動物としてのラットの有用性
  
  Volume: 78 Pages: 16-19
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Down-Regulation of Astrocytic Kir4.1 Channels during the Audiogenic Epileptogenesis in Leucine-Rich Glioma-Inactivated 1 (Lgi1) Mutant Rats.2019
- Author(s)
  Masato Kinboshi , Saki Shimizu, Tomoji Mashimo, Tadao Serikawa, Hidefumi Ito, Akio Ikeda, Ryosuke Takahashi, Yukihiro Ohno
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 5 Pages: 001-015
- DOI
  10.3390/ijms20051013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-INTERNATIONAL-15K21731, KAKENHI-ORGANIZER-15H05871, KAKENHI-PLANNED-15H05874, KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-17K08324, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-19H03574
[Journal Article] ラット受精卵でのゲノム編集2019
- Author(s)
  吉見一人、真下知士
- Journal Title
  
  実験医学別冊　ゲノム編集実験スタンダード
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-18KK0307
[Journal Article] CLICK: one-step generation of conditional knockout mice.2018
- Author(s)
  Miyasaka Y, Uno Y, Yoshimi K, Kunihiro Y, Yoshimura T, Tanaka T, Ishikubo H, Hiraoka Y, Takemoto N, Tanaka T, Ooguchi Y, Skehel P, Aida T, Takeda J, Mashimo T.
- Journal Title
  
  BMC Genomics.
  
  Volume: 19 Issue: 1 Pages: 318-318
- DOI
  10.1186/s12864-018-4713-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17KT0126, KAKENHI-PROJECT-17K08632, KAKENHI-PROJECT-16K18402, KAKENHI-PROJECT-18H03974
[Journal Article] Involvement of complement 3 in the salt-sensitive hypertension by activation of renal renin-angiotensin system in spontaneously hypertensive rats2018
- Author(s)
  Negishi Eriko、Fukuda Noboru、Otsuki Tomoyasu、Katakawa Mayumi、Komatsu Kazutoshi、Chen Lan、Tanaka Sho、Kobayashi Hiroki、Hatanaka Yoshinari、Ueno Takahiro、Endo Morito、Mashimo Tomoji、Nishiyama Akira、Abe Masanori
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 315 Issue: 6 Pages: F1747-F1758
- DOI
  10.1152/ajprenal.00370.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H03974
[Journal Article] Rats deficient C-type natriuretic peptide suffer from impaired skeletal growth without early death.2018
- Author(s)
  Fujii T, Hirota K, Yasoda A, Takizawa A, Morozumi N, Nakamura R, Yotsumoto T, Kondo E, Yamashita Y, Sakane Y, Kanai Y, Ueda Y, Yamauchi I, Yamanaka S, Nakao K, Kuwahara K, Jindo T, Furuya M, Mashimo T, Inagaki N, Serikawa T, Nakao K.
- Journal Title
  
  PROS ONE
  
  Volume: 13 Issue: 3 Pages: e0194812-e0194812
- DOI
  10.1371/journal.pone.0194812
- NAID
  120006466606
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09881, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-16K15442
[Journal Article] Creating a stem cell niche in the inner ear using self-assembling peptide amphiphiles2017
- Author(s)
  Matsuoka Akihiro J.、Sayed Zafar A.、Stephanopoulos Nicholas、Berns Eric J.、Wadhwani Anil R.、Morrissey Zachery D.、Chadly Duncan M.、Kobayashi Shun、Edelbrock Alexandra N.、Mashimo Tomoji、Miller Charles A.、McGuire Tammy L.、Stupp Samuel I.、Kessler John A.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 12 Pages: e0190150-e0190150
- DOI
  10.1371/journal.pone.0190150
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Tremor dominant Kyoto ( Trdk ) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca 2+ -activated K + channel2017
- Author(s)
  Kuramoto Takashi、Yokoe Mayuko、Kunisawa Naofumi、Ohashi Kana、Miyake Takahito、Higuchi Yuki、Yoshimi Kazuto、Mashimo Tomoji、Tanaka Miyuu、Kuwamura Mitusru、Kaneko Shuji、Shimizu Saki、Serikawa Tadao、Ohno Yukihiro
- Journal Title
  
  Brain Research
  
  Volume: 1676 Pages: 38-45
- DOI
  10.1016/j.brainres.2017.09.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K21501, KAKENHI-PROJECT-26290033
[Journal Article] A rat model of ataxia-telangiectasia: evidence for a neurodegenerative phenotype.2017
- Author(s)
  Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 26(1) Pages: 109-123
- DOI
  10.1093/hmg/ddw371
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Application of genome editing technologies in rats for human disease models2017
- Author(s)
  Yoshimi Kazuto、Mashimo Tomoji
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Issue: 2 Pages: 115-123
- DOI
  10.1038/s10038-017-0346-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18402, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-16H06276
[Journal Article] From engineering to editing the rat genome2017
- Author(s)
  Meek Stephen、Mashimo Tomoji、Burdon Tom
- Journal Title
  
  Mamm Genome
  
  Volume: 28 Issue: 7-8 Pages: 302-314
- DOI
  10.1007/s00335-017-9705-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-16H06276
[Journal Article] Synaptic vesicle glycoprotein 2A (SV2A) regulates kindling epileptogenesis via GABAergic neurotransmission.2016
- Author(s)
  Tokudome K, Okumura T, Shimizu S, Mashimo T, Takizawa A, Serikawa T, Terada R, Ishihara S, Kunisawa N, Sasa M, Ohno Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 2742-2742
- DOI
  10.1038/srep27420
- NAID
  120006349333
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage.2016
- Author(s)
  Quek H, Luff J, Cheung K, Kozlov S, Gatei M, Lee CS, Bellingham MC, Noakes PG, Lim YC, Barnett NL, Dingwall S, Wolvetang E, Mashimo T, Roberts TL, Lavin MF.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: - Issue: 4 Pages: 927-947
- DOI
  10.1189/jlb.4vma0716-316r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26291005
[Journal Article] Depdc5 knockout rat: A novel model of mTORopathy.2016
- Author(s)
  Marsan E, Ishida S, Schramm A, Weckhuysen S, Muraca G, Lecas S, Liang N, Treins C, Pende M, Roussel D, Le Van Quyen M, Mashimo T, Kaneko T, Yamamoto T, Sakuma T, Mahon S, Miles R, Leguern E, Charpier S, Baulac S.
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 9;89 Pages: 180-189
- DOI
  10.1016/j.nbd.2016.02.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes.2016
- Author(s)
  Yoshimi K, Kunihiro Y, Kaneko T, Nagahora H, Voigt B, Mashimo T.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 10431-10431
- DOI
  10.1038/ncomms10431
- NAID
  120005743652
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] A Missense Mutation of the Gene Encoding Synaptic Vesicle Glycoprotein 2A (SV2A) Confers Seizure Susceptibility by Disrupting Amygdalar Synaptic GABA Release.2016
- Author(s)
  Tokudome K, Okumura T, Terada R, Shimizu S, Kunisawa N, Mashimo T, Serikawa T, Sasa M, Ohno Y.
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 7 Pages: 210-210
- DOI
  10.3389/fphar.2016.00210
- NAID
  120006331984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26460111
[Journal Article] Fat Mass Reduction With Adipocyte Hypertrophy and Insulin Resistance in Heterozygous PPARγ Mutant Rats.2016
- Author(s)
  Gumbilai V, Ebihara K, Aizawa-Abe M, Ebihara C, Zhao M, Yamamoto Y, Mashimo T, Hosoda K, Serikawa T, Nakao K.
- Journal Title
  
  Diabetes
  
  Volume: 65(10) Issue: 10 Pages: 2954-65
- DOI
  10.2337/db15-1422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26461335
[Journal Article] Generation of a new model rat: Nrf2 knockout rats are sensitive to aflatoxin B1 toxicity.2016
- Author(s)
  Taguchi K, Takaku M, Egner PA, Morita M, Kaneko T, Mashimo T, Kensler TW, Yamamoto M.
- Journal Title
  
  Toxicol Sci
  
  Volume: in press Issue: 1 Pages: 40-52
- DOI
  10.1093/toxsci/kfw065
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460384, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26291005, KAKENHI-PROJECT-15KK0325, KAKENHI-INTERNATIONAL-15K21759
[Journal Article] Advances on genetic rat models of epilepsy2015
- Author(s)
  Serikawa T, Mashimo T, Kuramoto T, Voigt B, Ohno Y, Sasa M.
- Journal Title
  
  Exp. Anim.
  
  Volume: 64 Issue: 1 Pages: 1-7
- DOI
  10.1538/expanim.14-0066
- NAID
  130004694009
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Creating Knockout and Knockin Rodents Using Engineered Endonucleases via Direct Embryo Injection.2015
- Author(s)
  Kaneko T, Mashimo T.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1239 Pages: 307-315
- DOI
  10.1007/978-1-4939-1862-1_18
- ISBN
  9781493918614, 9781493918621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] X-linked severe combined immunodeficiency (X-SCID) rats for xeno-transplantation and behavioral evaluation2015
- Author(s)
  Bumpei Samata, Tetsuhiro Kikuchi, Yoshifumi Miyawaki, Asuka Morizane, Tomoji Mashimo, Masato Nakagawa, Keisuke Okita, Jun Takahashi
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: 243 Pages: 68-77
- DOI
  10.1016/j.jneumeth.2015.01.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-14J02729, KAKENHI-PROJECT-24590353, KAKENHI-PROJECT-25293308, KAKENHI-PROJECT-26290033
[Journal Article] ・Seipin is necessary for normal brain development and spermatogenesis in addition to adipogenesis.2015
- Author(s)
  Ebihara C, Ebihara K, Aizawa-Abe M, Mashimo T, Tomita T, Zhao M, Gumbilai VM, Kusakabe T, Yamamoto Y, Aotani D, Yamamoto-Kataoka S, Sakai T, Hosoda K, Serikawa T, Nakao K
- Journal Title
  
  Hum Mol Genet
  
  Volume: 24 Issue: 15 Pages: 4238-4249
- DOI
  10.1093/hmg/ddv156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461333, KAKENHI-PROJECT-24390237, KAKENHI-PROJECT-26290033
[Journal Article] 実験用ラットにおけるゲノム編集技術の福音2015
- Author(s)
  真下知士
- Journal Title
  
  医学のあゆみ
  
  Volume: 252(2) Pages: 171-176
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Novel ENU-induced mutation in Tbx6 causes dominant spondylocostal dysostosis-like vertebral malformations in the rat.2015
- Author(s)
  Abe K, Takamatsu N, Ishikawa K, Tsurumi T, Tanimoto S, Sakurai Y, Lisse T, Serikawa T, Mashimo T.
- Journal Title
  
  PLoS ONE
  
  Volume: 10 Issue: 6 Pages: e0130231-e0130231
- DOI
  10.1371/journal.pone.0130231
- NAID
  120005947155
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25290036, KAKENHI-PROJECT-26290033
[Journal Article] Simple Genome Editing of Rodent Intact Embryos by Electroporation2015
- Author(s)
  Kaneko T, Mashimo T.
- Journal Title
  
  PLoS One
  
  Volume: 10(11) Issue: 11 Pages: e0142755-e0142755
- DOI
  10.1371/journal.pone.0142755
- NAID
  120005743644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Methylphenidate improves learning impairments and hyperthermia-induced seizures caused by an Scn1a mutation.2014
- Author(s)
  Ohmori, I., Kawakami, N., Liu, S., Wang, H., Miyazaki, I., Asanuma, M., Michiue, H., Matsui, H., Mashimo, T. and Ouchida, M.
- Journal Title
  
  Epilepsia
  
  Volume: 55 Issue: 10 Pages: 1558-1567
- DOI
  10.1111/epi.12750
- NAID
  120005522498
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659431, KAKENHI-PROJECT-25461279, KAKENHI-PROJECT-26670500
[Journal Article] 効率的な遺伝子改変動物の作製方法について2014
- Author(s)
  真下知士
- Journal Title
  
  遺伝子治療・診断の最先端技術と新しい医薬品・診断薬の開発
  
  Volume: 13(1) Pages: 499-503
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] ラットにおけるゲノム編集技術革命2014
- Author(s)
  吉見一人、金子武人、真下知士
- Journal Title
  
  実験医学
  
  Volume: 32(11) Pages: 1715-1720
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platform.2014
- Author(s)
  Kazuto Yoshimi, Takehito Kaneko, Birger Voigt, Tomoji Mashimo
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 4240-4240
- DOI
  10.1038/ncomms5240
- NAID
  120005451811
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25890011, KAKENHI-PROJECT-26290033
[Journal Article] Simple knockout by electroporation of engineered endonucleases into intact rat embryos2014
- Author(s)
  Kaneko T, Sakuma T, Yamamoto T, Mashimo T
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 6382-6382
- DOI
  10.1038/srep06382
- NAID
  120005477670
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25890014, KAKENHI-PROJECT-26290033
[Journal Article] 人工ヌクレアーゼによる新しい遺伝子改変動物の作製法2014
- Author(s)
  真下知士
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 44(2) Pages: 79-82
- Data Source
  KAKENHI-PROJECT-26290033
[Journal Article] ラットにおける遺伝子改変技術の新展開2013
- Author(s)
  真下知士、金子武人
- Journal Title
  
  細胞工学
  
  Volume: Vol. 32、No.5 Pages: 564-569
- Data Source
  KAKENHI-PROJECT-24700427
[Journal Article] Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes2013
- Author(s)
  Tomoji Mashimo
- Journal Title
  
  Scientific Reports
  
  Volume: 3 Issue: 1 Pages: 1253-1253
- DOI
  10.1038/srep01253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J06938, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-24310041, KAKENHI-PROJECT-24700427
[Journal Article] Repeating pattern of non-RVD variations in DNA-binding modules enhances TALEN activity.2013
- Author(s)
  Sakuma T, Ochiai H, Kaneko T, Mashimo T, Tokumasu D, Sakane Y, Suzuki K, Miyamoto T, Sakamoto N, Matsuura S, Yamamoto T
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Issue: 1 Pages: 3379-3379
- DOI
  10.1038/srep03379
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22124001, KAKENHI-PROJECT-23710068, KAKENHI-PROJECT-24310043, KAKENHI-PROJECT-24651222, KAKENHI-PROJECT-24657156, KAKENHI-PROJECT-24700427, KAKENHI-PUBLICLY-25113521, KAKENHI-PUBLICLY-25124708, KAKENHI-PROJECT-25890014
[Journal Article] Generation and characterization of severe combined immune deficientrats.2012
- Author(s)
  Mashimo T, Takizawa A, Kobayashi J, Kunihiro Y, Yoshimi K, Ishida S, Tanabe K, Yanagi A, Tachibana A, Hirose J, Yomoda J, Morimoto S, Kuramoto T, Voigt B, Watanabe T, Hiai H, Tateno C, Komatsu K, Serikawa T.
- Journal Title
  
  Cell Reports
  
  Volume: 2(3) Issue: 3 Pages: 685-694
- DOI
  10.1016/j.celrep.2012.08.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J03639, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-23241021, KAKENHI-PROJECT-24310041, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111009
[Journal Article] A rat model for Lgi1-related epilepsies2012
- Author(s)
  *Baulac S, Ishida S, *Mashimo T, Boillot M, Fumoto N, Kuwa mura M, Ohno Y, Takizawa A, Aoto T, Ueda M, Ikeda A, Leguern E, Takahashi R, Serikawa T
- Journal Title
  
  Hum Mol Genet
  
  Volume: 21(16) Issue: 16 Pages: 3546-57
- DOI
  10.1093/hmg/dds184
- NAID
  120005244992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-23390232, KAKENHI-PROJECT-23591275, KAKENHI-ORGANIZER-23111001, KAKENHI-PLANNED-23111002
[Journal Article] ジンクフィンガーヌクレアーゼ(ZFN)2012
- Author(s)
  真下知士、芹川忠夫
- Journal Title
  
  細胞工学
  
  Volume: 31(3) Pages: 296-301
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] ジンクフィンガーヌクレアーゼによる遺伝子改変動物の作製2012
- Author(s)
  真下知士、芹川忠夫
- Journal Title
  
  Medical Science Digest
  
  Volume: 38(1) Pages: 10-11
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] 新しい遺伝子改変技術「ジンクフィンガーヌクレアーゼ(ZFN)」2011
- Author(s)
  真下知士
- Journal Title
  
  化学と生物
  
  Volume: 49(4) Pages: 220-222
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] Kcnal-mutant rats dominantly display myokymia, neuromyotonia and spontaneous epileptic seizures2011
- Author(s)
  Ishida S, et al
- Journal Title
  
  Brain Research
  
  Volume: 1435 Pages: 154-166
- DOI
  10.1016/j.brainres.2011.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21390022, KAKENHI-PROJECT-21680037
[Journal Article] The rapy for hyper ther mia-induced seizures in Scn1a mutant rats2011
- Author(s)
  Hayashi K, Ueshima S, Ouchida M, Mashimo T, Nishiki T, Sendo T, Serikawa T, Matsui H, Ohmori I
- Journal Title
  
  Epilepsia
  
  Volume: 52(5) Issue: 5 Pages: 1010-1017
- DOI
  10.1111/j.1528-1167.2011.03046.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-23659522
[Journal Article] Scnla missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures2011
- Author(s)
  Y.Ohno, et al
- Journal Title
  
  Neurobiol.Dis
  
  Volume: 41 Issue: 2 Pages: 261-269
- DOI
  10.1016/j.nbd.2010.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22590092
[Journal Article] Therapy for hyperthermia-induced seizures in Scn1a mutant rats2011
- Author(s)
  Hayashi K, Ueshima S, Ouchida M, Mashimo T, Nishiki T, Sendo T, Serikawa T, Matsui H, Ohmori I
- Journal Title
  
  Epilepsia
  
  Volume: 52(5) Pages: 1010-7
- NAID
  120005468280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390312
[Journal Article] Scn1a missense mutation impairs GABAA receptor-mediated synaptic transmission in the rat hippocampus2010
- Author(s)
  Ohno Y, Sofue N, Ishihara S, Mashimo T, Sasa M, Serikawa T
- Journal Title
  
  Biophys Res Commun
  
  Volume: 400(1) Pages: 117-122
- URL
  http://dx.doi.org/10.1016/j.bbrc.2010.08.021
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel(Na_v1. 1) confers susceptibility to febrile seizures in rats2010
- Author(s)
  Mashimo T, Ohmori I, Ouchida M, Ohno Y, Tsurumi T, Miki T, Wakamori M, Takizawa A, Kato M, Hirabayashi M, Sasa M, Mori Y, Serikawa T
- Journal Title
  
  J Neurosci
  
  Volume: 30 Pages: 5744-5753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390312
[Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel(Nav1. 1) confers susce ptibility to febrile seizures in rats2010
- Author(s)
  Mashimo T, Ohmori I, Ouchida M, Ohno Y, Tsurumi T, Miki T, Wakamori M, Ishihara S, Yoshida T, Takizawa A, Kato M, Hirabayashi M, Sasa M, Mori Y, Serikawa T
- Journal Title
  
  J Neurosci
  
  Volume: 30(16) Issue: 16 Pages: 5744-5753
- DOI
  10.1523/jneurosci.3360-09.2010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042, KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22659335
[Journal Article] ナトリウムチャネル遺伝子Scn1a変異ラットの開発解析研究2010
- Author(s)
  芹川忠夫, 大守伊織, 大内田守, 大野行弘, 鶴見東志子, 三木崇史, 若森実, 石原靜, 吉田卓史, 滝沢明子, 加藤めぐみ, 平林真澄, 笹征史, 森泰生, 真下知士
- Journal Title
  
  てんかん治療研究振興財団研究年報
  
  Volume: 第21集 Pages: 29-36
- Data Source
  KAKENHI-PROJECT-21390312
[Journal Article] A missense mutation of the geneencoding voltage-dependent sodiumchannel (Nav1.1) confers susceptibility tofebrile seizures in rats.2010
- Author(s)
  Mashimo T, Ohmori I, Ouchida M,Ohno Y, Tsurumi T, Miki T, Wakamori M,Ishihara S, Yoshida T, Takizawa A, Kato M,Hirabayashi M, Sasa M, Mori Y, SerikawaT.
- Journal Title
  
  J Neurosci 30
  
  Pages: 5744-5753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Scn1a missense mutation causes limbic hype rexcitability and vulne rability to expe rimental febrile seizures2010
- Author(s)
  Ohno Y, Ishihara S, Mashimo T, Sofue N, Shimizu S, Imaoku T, Tsurumi T, Sasa M, Serikawa T
- Journal Title
  
  Neurobiol Dis
  
  Volume: 41(2) Pages: 261-269
- URL
  http://dx.doi.org/10.1016/j.nbd.2010.09.013
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] ナトリウムチャネル遺伝子 Scn1a 変異ラットの開発解析研究2010
- Author(s)
  芹川忠夫、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、石原靜、吉田卓史、滝沢明子、加藤めぐみ、平林真澄、笹征史、森泰生、真下知士
- Journal Title
  
  てんかん治療研究振興財団研究年報
  
  Volume: 第21集
- URL
  http://jglobal.jst.go.jp/public/20090422/201102212688654898
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel(Navl. 1)confers susceptibility to febrile seizures in rats2010
- Author(s)
  Mashimo T
- Journal Title
  
  J Neuroscience 32巻第16号
  
  Pages: 5744-5753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390312
[Journal Article] Generation of knockout rats with X-linked severe combined immunodeficiency (X-SCID) using zinc-finger nucleases2010
- Author(s)
  Mashimo, et al., (他6人)
- Journal Title
  
  PLoS One 5(1)
- NAID
  120001850620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] A missense mutation of the gene encoding voltage-dependent sodium channel Na_v1.1 confers susceptibility to febrile seizures in rats.2010
- Author(s)
  Mashimo T, et al., (他14人)
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 30(16) Pages: 5744-5753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] Scn1a missense mutation impairs GABA(A) receptor-mediated synaptic transmission in the rat hippocampus.2010
- Author(s)
  Ohno Y, Sofue N, Ishihara S, Mashimo T, Sasa M, Serikawa T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 400(1) Issue: 1 Pages: 117-22
- DOI
  10.1016/j.bbrc.2010.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21680037, KAKENHI-PROJECT-22590092
[Journal Article] Rat resources in biomedical research.2009
- Author(s)
  Mashimo T, Serikawa T
- Journal Title
  
  Current Phamaceutical Biotechnology 10(2)
  
  Pages: 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] Rat resources in biomedical research.2009
- Author(s)
  *Mashimo T, Serikawa T
- Journal Title
  
  Curr Pharm Biotechnol
  
  Volume: 10(2) Pages: 214-20
- URL
  http://www.eurekaselect.com/68487/article
- Data Source
  KAKENHI-PROJECT-21680037
[Journal Article] Rat resources in biomedical research.2009
- Author(s)
  Mashimo T, Serikawa T.
- Journal Title
  
  Curr Pharm Biotechnol. 10(2)
  
  Pages: 214-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] An ENU-induced mutant archive for gene-targetting in rats.2008
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Nature Genet (in Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] An ENU-induced mutant archive for gene targeting in rats2008
- Author(s)
  Mashimo, T., et. al.
- Journal Title
  
  Nat Genet 40(5)
  
  Pages: 514-515
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] An ENU-induced mutant archive for gene-targeting in rats.2008
- Author(s)
  Mashimo T, et al., 他9人
- Journal Title
  
  Nature Genetics 40(5)
  
  Pages: 514-515
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] An ENU-induced mutant archive for gene targeting in rats.2008
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  Nat Genet. 40(5)
  
  Pages: 514-515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20240042
[Journal Article] Innate resistance to flavivirus infections and the functions of 2'-5' oligoadenylate synthetases.2008
- Author(s)
  Mashimo T, Simon D, Guenet JL
- Journal Title
  
  Current Topics in Microbiology and Immunology 321
  
  Pages: 85-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] A missense mutation in an ubiquitin E3 ligase gene results in Purkinje cells degeneration with severe ataxiia in mice.2008
- Author(s)
  Mashimo T, et al., 他3人
- Journal Title
  
  Neuroscience Research 61(S1)
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] AnENU-induced mutant archive for gene targeting in rats.2008
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Nat Genet. 40(5)
  
  Pages: 514-515
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] Scnla mutant rats established by gene-driven ENU mutagenesis.2007
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Neuroscience Research 58(S1)
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] A comprehensive QTL analysis of serum cholesterol levelsbefore and after a high-cholesterol diet in SHRSP.2007
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Physiological Genomics 30
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19650106
[Journal Article] A comprehensive QTL analysis of serum cholesterol levels before and after a high-cholesterol diet in SHRSP.2007
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Physiological Genomics 30(2)
  
  Pages: 95-101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] A comprehensive QTL analysis of serum cholesterol levels before and after a high-cholesterol diet in SHRSP.2007
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  Physiological Genomics (in press)
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] Two quantitative trait loci affecting progressive hearing loss in 101/H mice.2006
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  Mammalian Genome 17・8
  
  Pages: 841-850
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains.2006
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  BMC Genetics in press
- NAID
  120004770256
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] A set of highly informative rat simple sequence length polymorphism (SSLP) markers and genetically defined rat strains.2006
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  BMC Genetics 7
  
  Pages: 19-19
- NAID
  120004770256
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] ラットフェノームプロジェクト:NBRP-Ratに寄託されたラット系統の体系的特性評価2006
- Author(s)
  真下知士, 他
- Journal Title
  
  疾患モデル通信 21
  
  Pages: 3-4
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] Application for the National Bio Resource Project for the Rat (NBRP-Rat).2006
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  Clinical Experimental Hypertension 28・6
  
  Pages: 578-578
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] ラットフェノームプロジェクト:ラット既存系統の体系的特性評価2005
- Author(s)
  真下知士, 他
- Journal Title
  
  日本疾患モデル学会記録 21
  
  Pages: 17-21
- NAID
  130000760626
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] Rat Phenome Project : the untapped potential of existing rat strains.2005
- Author(s)
  Mashimo T, et al.
- Journal Title
  
  J Appl Physiol Jan ; 98(1)
  
  Pages: 371-379
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] ラットフェノームプロジェクト:ラット既存系統の体系的特性評価2005
- Author(s)
  真下知士, 他
- Journal Title
  
  日本疾患モデル学会記録 21
  
  Pages: 17-21
- NAID
  130000760626
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] 実験用ラットの有用性-ナショナルバイオリソースプロジェクト「ラット」2005
- Author(s)
  真下知士, 他
- Journal Title
  
  遺伝 59・3
  
  Pages: 79-84
- NAID
  40006736598
- Data Source
  KAKENHI-PROJECT-17700378
[Journal Article] 実験用ラットの有用性-ナショナルバイオリソースプロジェクト「ラット」-2005
- Author(s)
  真下知士, 他
- Journal Title
  
  遺伝 59(3)
  
  Pages: 79-84
- NAID
  40006736598
- Data Source
  KAKENHI-PROJECT-16200029
[Journal Article] An ENU-induced mutant archive for gene-targeting in rats.
- Author(s)
  Mashimo T, et. al.
- Journal Title
  
  Nature Genetics (in press)
- Data Source
  KAKENHI-PROJECT-19650106
[Patent] ＣＲＩＳＰＲ－Ｃａｓシステム、標的ＤＮＡを編集する方法、標的ＤＮＡが編集された細胞を製造する方法、標的ＤＮＡを検出する方法、及びキット2024
- Inventor(s)
  真下知士、吉見一人、阿部洋、阿部奈保子
- Industrial Property Rights Holder
  真下知士、吉見一人、阿部洋、阿部奈保子
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-047341
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23H00367
[Patent] 改良されたＣＲＩＳＰＲ－Ｃａｓ３システム2024
- Inventor(s)
  雑賀啓明、真下知士、吉見一人、村中俊哉、安本周平
- Industrial Property Rights Holder
  雑賀啓明、真下知士、吉見一人、村中俊哉、安本周平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2024-042105
- Filing Date
  2024
- Data Source
  KAKENHI-PROJECT-23H00367
[Patent] 試料中の特定のＤＮＡを検出する方法2021
- Inventor(s)
  真下知士、吉見一人、渋村里美
- Industrial Property Rights Holder
  大阪大学、C4U株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-18H03974
[Patent] Cas3タンパク質を製造する方法2021
- Inventor(s)
  真下知士、吉見一人、竹下浩平、山本雅貴、渋村里美
- Industrial Property Rights Holder
  東京大学、理化学研究所、C4U株式会社
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-031907
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-18H03974
[Patent] 試料中の特定のＤＮＡを検出する方法2020
- Inventor(s)
  真下知士、吉見一人、渋村里美
- Industrial Property Rights Holder
  大阪大学、C4U株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18H03974
[Patent] 遺伝子改変非ヒトモデル動物2019
- Inventor(s)
  大守伊織, 大内田守, 真下知士
- Industrial Property Rights Holder
  大守伊織, 大内田守, 真下知士
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-514326
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-16H06276
[Patent] ゲノム編集方法2016
- Inventor(s)
  真下知士、宮坂佳樹
- Industrial Property Rights Holder
  大阪大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-11-28
- Data Source
  KAKENHI-PROJECT-26290033
[Patent] 哺乳動物の標的ゲノム領域にDNAをノックインする方法及び細胞2014
- Inventor(s)
  真下知士、吉見一人、金子武人
- Industrial Property Rights Holder
  真下知士、吉見一人、金子武人
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-235898
- Filing Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-26290033
[Patent] 標的遺伝子中にミスマッチを有する生物のスクリーニング方法2006
- Inventor(s)
  真下知士, 他
- Industrial Property Rights Holder
  京都大学
- Filing Date
  2006-01-11
- Data Source
  KAKENHI-PROJECT-16200029
[Patent] 標的遺伝子中にミスマッチを有する生物のスクリーニング方法2006
- Inventor(s)
  真下知士, 他
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-003855
- Filing Date
  2006-01-11
- Data Source
  KAKENHI-PROJECT-17700378
[Patent] 標的遺伝子中にミスマッチを有する生物のスクリーニング方法2006
- Inventor(s)
  真下知士、柳原克彦、徳田智子、芹川忠夫
- Industrial Property Rights Holder
  京都大学
- Industrial Property Number
  2006-003855
- Filing Date
  2006-01-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] ゲノム編集の研究2024
- Author(s)
  真下　知士
- Organizer
  ゲノム創薬・創発フォーラム第14回シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA2変異のフェロトーシス抵抗性獲得因子の探索2024
- Author(s)
  前田勇貴、真下知士、豊國伸哉
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] ゲノム編集技術による遺伝子改変動物の作製2024
- Author(s)
  真下　知士
- Organizer
  第4回有性生殖研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA2の生殖細胞変異は卵胞発育を促進し卵巣予備能の低下を惹起する2024
- Author(s)
  田中秀明、本岡大社、前田勇貴、真下知士、梶山広明、豊國伸哉
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] BRCA2変異はp53活性を抑制しフェロトーシス抵抗性を獲得する2023
- Author(s)
  前田勇貴、真下知士、豊國伸哉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] Genome editing technologies and humanized rats, The 36th International Mammalian Genome Conference (IMGC2023)2023
- Author(s)
  Tomoji Mashimo
- Organizer
  第36回国際哺乳類ゲノム会議
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集研究の現状と課題2023
- Author(s)
  真下　知士
- Organizer
  第87回生化学会中部支部例会・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA2変異は酸化ストレス環境下でAKTシグナルを介したふぇろトーシス抵抗性を誘導する2023
- Author(s)
  前田勇貴、真下知士、豊國伸哉
- Organizer
  日本酸化ストレス学会東海支部　第12回学術集会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] BRCA1ハプロ不全とフェントン反応による発癌過程：ミトコンドリア代謝への影響2023
- Author(s)
  孔穎怡、真下知士、今岡達彦、豊國伸哉
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] BRCA2 変異はDNA傷害下でp21の局在を変化させ細胞周期チェックポイント破綻を引き起こす2023
- Author(s)
  前田勇貴、真下知士、豊國伸哉
- Organizer
  第30回日本がん予防学会総会会長　祖父江友孝・第46回日本がん疫学・分子疫学研究会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] ゲノム編集がひらく明るい未来2023
- Author(s)
  真下知士
- Organizer
  ゲノム編集の未来を考える会メディアセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] Genome Editing technologies in mice and rats2023
- Author(s)
  真下　知士
- Organizer
  AHLAS CONGRESS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] ゲノム編集技術とゲノム編集モデル動物を用いた研究2023
- Author(s)
  真下　知士
- Organizer
  第26回日本小児心血管分子医学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA2の生殖細胞変異は卵胞発育を促進し卵巣予備能の低下を惹起する2023
- Author(s)
  田中秀明、本岡大社、前田勇貴、真下知士、梶山広明、豊國伸哉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] Txn1遺伝子変異ラットにおける慢性腎臓病は、ミトコンドリア異常と複数の細胞死パスウェイが関与する2023
- Author(s)
  大守伊織、大内田守、秦昌紫子、内田治仁、豊國伸哉、真下知士
- Organizer
  第34回腎とフリーラジカル研究会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] BRCA2生殖細胞系列変異が卵巣予備能低下へ及ぼす影響について2023
- Author(s)
  田中秀明、本岡大社、前田勇貴、真下知士、梶山広明、豊國伸哉
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] CRISPR-Cas3, a Genome Editing Technology, in Genome Therapy2023
- Author(s)
  Tomoji Mashimo
- Organizer
  IMSUT NY Seminar 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術による神経科学研究に有用なモデル動物の開発2023
- Author(s)
  真下　知士
- Organizer
  第46回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA2変異モデルラットの卵巣機能に対する加齢とPARP阻害剤オラパリブの影響2023
- Author(s)
  曽根原玲奈、本岡大社、真下知士、今岡龍彦、梶山広明、豊國伸哉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] フェントン反応による発癌過程においてミトコンドリア代謝に注目したBRCA1ハプロ不全の追跡2023
- Author(s)
  孔穎怡、真下知士、今岡龍彦、豊國伸哉
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] Neuropathological analyses of a novel neuroaxonal dystrophy model rat 新たに確立した神経軸索ジストロフィーモデルラットの神経病理学的解析2023
- Author(s)
  藤川諒子，田中美有，関口隆寛，服部晃佑，井澤武史，真下知士，桑村充，芹川忠夫，庫本高志
- Organizer
  The 10th ASVP and 10th JCVP Joint Conference 第10回アジア獣医病理学会/第10回日本獣医病理学専門家協会合同学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] Post-Cas9” Genome Editing - Paving the Way for Industrial Applications2023
- Author(s)
  真下　知士
- Organizer
  JAACT2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23H00367
[Presentation] BRCA1 欠損は腎臓における鉄代謝の変化と酸化ストレスによる腎発がんに関わる2022
- Author(s)
  孔穎怡、真下知士、今岡達彦、豊國伸哉
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] 遺伝子編集技術 CRISPR-Cas3 の概要と応用事例について2022
- Author(s)
  真下知士
- Organizer
  第40回JBDAバイオベンチャーフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 新規ゲノム編集法の開発2022
- Author(s)
  真下知士
- Organizer
  名古屋大学生命農学研究科大学院セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] シンポジウム20：個別化予防医療・先制医療　BRCA1のハプロ不全は、腎臓発がん過程においてフェロトーシス抵抗性を獲得することにより染色体増幅を促進する2022
- Author(s)
  孔穎怡、赤塚慎也、本岡大社、鄭好、白木之浩、真下知士、今岡達彦、豊國伸哉
- Organizer
  第81回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] げっ歯類癌モデルにおけるフェロトーシス抵抗性2022
- Author(s)
  豊國伸哉、孔穎怡、赤塚慎也、本岡大社、鄭好、真下知士、今岡達彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] ゲノム編集動物作製とCRISPR診断薬CONAN2022
- Author(s)
  吉見一人・真下知士
- Organizer
  UTOPIAキックオフミーティング
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集CRISPR-Cas3の遺伝子治療に向けた研究開発について2022
- Author(s)
  真下知士
- Organizer
  ヒトゲノム編集技術のガバナンスと基礎研究・臨床応用に関する委員会（第２５期・第３回）
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] A genome editing technology CRISPR-Cas3 in gene therapy, Institute for the Advanced Study of Human Biology2022
- Author(s)
  真下知士
- Organizer
  WPI-ASHBi　Seminar.
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] BRCA1欠損はフェロトーシス抵抗性を誘導することによりアスベスト誘発性腹膜中皮腫を促進する2022
- Author(s)
  羅亜光、本岡大社、赤塚慎也、真下知士、今岡達彦、豊國伸哉
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] BRCA1 生殖細胞系列変異による卵巣予備能低下と脂質過酸化の関与2022
- Author(s)
  曽根原玲菜、本岡大社、梶山広明、真下知士、今岡達彦、豊國伸哉
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] RISPR-Cas3を中心とした最新のゲノム編集技術と応用2022
- Author(s)
  真下知士
- Organizer
  富士フィルム株式会社Rゼミ講演
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] BRCA1 haploinsufficiency promotes chromosomal amplification under Fenton reaction-based carcinogenesis through ferroptosis-resistance.2022
- Author(s)
  Kong Y, Akatsuka S, Motooka Y, Zheng H, Cheng Z, Shiraki Y, Mashimo T, Imaoka T, Toyokuni S
- Organizer
  第29回日本がん予防学会総会
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] ラットにおける遺伝子改変技術とヒト化動物の現状と展望2022
- Author(s)
  真下知士
- Organizer
  公益社団法事日本実験動物学会主催第10回実験動物科学シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術とその医療応用/ゲノム編集を応用した毒性病理学の新展開2022
- Author(s)
  真下知士
- Organizer
  第38回日本毒性病理学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集CRISPR-Cas3の現状と展開2022
- Author(s)
  真下知士
- Organizer
  第127回日本解剖学会全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] A novel genome editing technology2022
- Author(s)
  Tomoji Mashimo
- Organizer
  CRISPR-Cas3, PASTEUR JAPAN 2022 SYMPOSIUM
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 遺伝子編集技術CRISPR-Cas3の概要と応用事例について2022
- Author(s)
  真下知士
- Organizer
  第3回エリクサジェンサイエンティフィックセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] A new genome editing technology CRISPR-Cas32022
- Author(s)
  Tomoji Mashimo
- Organizer
  World Science Leaders' Seminar in Doctoral Program in Human Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] BRCA1ハプロ不全はフェントン反応を基盤とする発がんにおいてフェロトーシス抵抗性と染色体増幅を促進する2022
- Author(s)
  孔穎怡、赤塚慎也、本岡大社、鄭好、白木之浩、真下知士、今岡達彦、豊國伸哉
- Organizer
  第33回日本微量元素学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22H04922
[Presentation] 次世代型ゲノム編集技術の開発2021
- Author(s)
  真下知士
- Organizer
  第73回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集が拓く疾患モデル研究2021
- Author(s)
  真下知士
- Organizer
  第17 回北海道実験動物研究会(HALAS)学術集会特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術概論と新規国産ゲノム編集技術について2021
- Author(s)
  真下知士
- Organizer
  第 427 回 CBI 学会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 新規ゲノム編集技術CRISPR－Cas３の開発と応用2021
- Author(s)
  真下知士
- Organizer
  シンポジウム2021－維新の地から挑む革新的医療技術の創出ー文部科学省
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集が拓く疾患モデル研究2021
- Author(s)
  真下知士
- Organizer
  第17 回北海道実験動物研究会(HALAS)学術集会特別講演
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3を用いたゲノム編集の可能性2021
- Author(s)
  真下知士
- Organizer
  第38回日本植物バイオテクノロジー学会（つくば）大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 新規国産ゲノム編集技術 CRISPR-Cas3 の開発と医療応用/Development of a Novel Genome Editing Tool CRISPR-Cas32021
- Author(s)
  真下知士
- Organizer
  日本ゲノム編集学会第６回大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集技術の最新動向2021
- Author(s)
  真下知士
- Organizer
  第21回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] A novel genome editing tool CRISPR Cas32021
- Author(s)
  真下知士
- Organizer
  48 th IMSUT Founding Commemorative Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3 の遺伝子治療応用と今後の可能性について2021
- Author(s)
  真下知士
- Organizer
  JBA創薬モダリティ基盤研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集が拓く疾患モデル研究の最先端2021
- Author(s)
  真下知士
- Organizer
  第68回日本実験動物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集とヒト化動物2021
- Author(s)
  真下知士
- Organizer
  実験動物に感謝する集い（招待講演）
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集とヒト化動物2021
- Author(s)
  真下知士
- Organizer
  実験動物に感謝する集い
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 次世代型ゲノム編集技術の開発2021
- Author(s)
  真下知士
- Organizer
  第73回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] グルタミン酸脱炭酸酵素67kDaアイソフォーム(GAD67)ノックアウトラットが示す恐怖記憶の変化2021
- Author(s)
  藤原和之、佐藤匠、宮坂佳樹、真下知士、柳川右千夫
- Organizer
  先端モデル動物支援プラットフォーム若手技術講習会2021
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集技術の開発や新しいモデル動物の開発動向などについて2021
- Author(s)
  真下知士
- Organizer
  日本実験動物協同組合(JCALA)の研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 脳神経疾患・モデルの開発2021
- Author(s)
  真下知士
- Organizer
  日中ハイレベル研究者交流会～パブリックヘルスと生命システム科学～
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 脳神経疾患・モデルの開発2021
- Author(s)
  真下知士
- Organizer
  日中ハイレベル研究者交流会～パブリックヘルスと生命システム科学～
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 創薬モダリティの進化2021
- Author(s)
  真下知士
- Organizer
  Bio Japan　2021セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集技術の最新動向2021
- Author(s)
  真下知士
- Organizer
  第21回日本抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] チオレドキシンの機能低下は神経細胞とオリゴデンドロサイトの細胞死を惹起する2021
- Author(s)
  大守伊織, 大内田守, 今井宏彦, 豊國伸哉, 真下知士
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Application of genome editing technology CRISPR-Cas3 in gene therapy2021
- Author(s)
  真下知士
- Organizer
  第27回東アジアシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集技術の開発や新しいモデル動物の開発動向などについて2021
- Author(s)
  真下知士
- Organizer
  日本実験動物協同組合(JCALA)の研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 慢性腎臓病を伴う早発老化モデル動物の発見2021
- Author(s)
  大内田守, 大守伊織, 今井宏彦, 豊國伸哉, 真下知士
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新型コロナウイルスの迅速診断法を語る2021
- Author(s)
  真下知士
- Organizer
  サイエンス映像学会（SVS）月例研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集が拓く疾患モデル研究の最先端2021
- Author(s)
  真下知士
- Organizer
  第68回日本実験動物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] CRISPER-Cas3によるゲノム編集と医療応用2021
- Author(s)
  真下知士
- Organizer
  第15回iPS細胞産学合同研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 遺伝子編集が拓く疾患モデル研究のフロンティア2020
- Author(s)
  真下知士
- Organizer
  第56回高血圧関連疾患モデル学会学術総会、理事長企画／未病栄養シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3がもたらす新たなゲノム編集基盤技術2020
- Author(s)
  真下知士
- Organizer
  千里ライフサイエンスセミナー「ゲノム編集がもたらす革新と更なる展望」
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] CRISPR-Cas3 による新しいゲノム編集2020
- Author(s)
  真下知士
- Organizer
  第72回日本細胞生物学会大会S10次世代型ゲノム編集技術の開発とその応用
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 転写と共役したDNA修復機構にはRNAPIIのユビキチン化修飾が必須である.2020
- Author(s)
  中沢由華, 原雄一郎, 岡泰由, 小峯起, Diana van den Heuvel, 郭朝万, 大学保一, 磯野真由, 何予希, 嶋田繭子, 加藤香奈, 賈楠, 橋下悟, 田中都, 祖父江顕, 光武範吏, 菅波孝祥, 増田章男, 大野欽司, 中田慎一郎, 真下知士, 山中宏二, Martijn S. Luijsterburg, 荻朋男.
- Organizer
  第10回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-20H00629
[Presentation] 遺伝子編集が拓く疾患モデル研究のフロンティア2020
- Author(s)
  真下知士
- Organizer
  第56回高血圧関連疾患モデル学会学術総会、理事長企画／未病栄養シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術とその医療応用：基礎技術的視点から2020
- Author(s)
  真下知士
- Organizer
  第2回 Translational and Regulatory Sciences Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術開発の現状と今後2020
- Author(s)
  真下知士
- Organizer
  ゲノム問題検討会議
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3: a new tool for genome editing and nucleic acid detection2020
- Author(s)
  Tomoji Mashimo
- Organizer
  The 15th International Symposium of the Institute Network for Biomedical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3: a new tool for genome editing and nucleic acid detection2020
- Author(s)
  Tomoji Mashimo
- Organizer
  The 15th International Symposium of the Institute Network for Biomedical Sciences ～Cutting Edge of Biomedical and Metabolic Sciences～
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 知財化された国産の新規ゲノム編集技術 Cas32020
- Author(s)
  真下知士
- Organizer
  iPS 細胞ビジネス協議会第34回情報交換会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] GABA合成酵素GAD67ハプロ不全と新生仔期NMDA型グルタミン酸受容体遮断の組み合わせにより生じる行動学的表現型2020
- Author(s)
  藤原和之、佐藤匠、宮坂佳樹、真下知士、柳川右千夫
- Organizer
  NPBPPP2020合同年会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] New CRISPR Technology for Genome Editing2020
- Author(s)
  Tomoji Mashimo
- Organizer
  第84回日本循環器学会学術集会Genome editing: CRISPR, Stem cells, and Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術とその医療応用：基礎技術的視点から2020
- Author(s)
  真下知士
- Organizer
  第2回 Translational and Regulatory Sciences Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] New CRISPR Technology for Genome Editing2020
- Author(s)
  Tomoji Mashimo
- Organizer
  第84回日本循環器学会学術集会Genome editing: CRISPR, Stem cells, and Beyond
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 新規ゲノム編集技術を用いた次世代CAR-T細胞療法の開発2020
- Author(s)
  真下知士
- Organizer
  先端的バイオ創薬等基盤技術開発事業研究者交流会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] Rapid and accurate detection of novel coronavirus SARS-CoV-2 using CRISPR-Cas32020
- Author(s)
  Tomoji Mashimo
- Organizer
  A Paradigm shift in Infectious Diseases: A Virtual Conference hosted by Merck KGaA
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 国産新規ゲノム編集技術 CRISPR-Cas32020
- Author(s)
  真下知士
- Organizer
  細胞・遺伝子治療―遺伝子解析のその先へー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Cas3がもたらす新たなゲノム編集基盤技術2020
- Author(s)
  真下知士
- Organizer
  基盤技術」」千里ライフサイエンスセミナー「ゲノム編集がもたらす革新と更なる展望」
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 動物生命科学におけるゲノム編集技術の利用2019
- Author(s)
  真下知士
- Organizer
  TARAセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] RISPR/Cas9-mediated genome editing in zygotes2019
- Author(s)
  Mashimo T
- Organizer
  The 9th International Forum on Laboratory Animal Science &Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 動物生命科学におけるゲノム編集技術の利用2019
- Author(s)
  真下知士
- Organizer
  TARAセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-mediated genome engineering and its application in animal models2019
- Author(s)
  Mashimo T
- Organizer
  22nd US-Japan Cellular and Gene Therapy Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] Roles of rat glutamate decarboxylase isoforms in the perinatal period2019
- Author(s)
  姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、柴崎貢志、石崎泰樹、宮坂佳樹、真下知士、柳川右千夫
- Organizer
  第42回日本神経科学大会第62回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Txn1遺伝子変異ラットのてんかんの表現型2019
- Author(s)
  大守伊織, 真下知土, 大内田守, 内藤有香, 今井宏彦, 豊國伸哉
- Organizer
  第53回日本てんかん学会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Txnl遺伝子ミスセンス変異をもつ新規CKDモデルラット2019
- Author(s)
  大守伊織, 真下知士, 大内田守, 豊國伸哉
- Organizer
  第62回日本腎臓病学会学術総会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集と重症免疫不全ラットの開発について2019
- Author(s)
  真下知士
- Organizer
  第90回信州実験動物研究会秋期勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 新規ゲノム編集ツール：CRISPR-Cas32019
- Author(s)
  真下知士
- Organizer
  関西スマートセルフォーラム2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集研究の進展と医工薬への応用2019
- Author(s)
  真下知士
- Organizer
  関西大学・大阪医科大学・大阪薬科大学医工薬連環科学教育研究機構研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR/Cas9-mediated genome editing in zygotes2019
- Author(s)
  Mashimo T
- Organizer
  The 9th International Forum on Laboratory Animal Science &Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 転写共役ヌクレオチド除去修復機構に重要なRNAポリメラーゼユビキチン化部位の同定.2019
- Author(s)
  中沢由華, 原雄一郎, 岡泰由, 小峯起, Diana van den Heuvel, 郭朝万, 大学保一, 磯野真由, 何予希, 嶋田繭子, 加藤香奈, 賈楠, 橋下悟, 小谷祐子, 三好由夏, 田中都, 祖父江顕, 光武範吏, 菅波孝祥, 増田章男, 大野欽司, 中田慎一郎, 真下知士, 山中宏二, Martijn S. Luijsterburg, 荻朋男.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H00783
[Presentation] ゲノム編集研究の進展と医工薬への応用2019
- Author(s)
  真下知士
- Organizer
  関西大学・大阪医科大学・大阪薬科大学医工薬連環科学教育研究機構研究セミナ
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] CRISPR/Cas3-mediated genome editing2019
- Author(s)
  Mashimo T
- Organizer
  The 3rd Frontiers in Genome Engineering Intl. Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム・細胞編集2019
- Author(s)
  真下知士
- Organizer
  JST-CRDS「治療用デザイナー細胞（微生物）」チームワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ラットにおける最先端生殖工学技術2019
- Author(s)
  真下知士
- Organizer
  第66回日本実験動物学会総会ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] GAD67ノックアウトラットの認知機能障害2019
- Author(s)
  藤原和之、柿崎利和、Jiang Weiru、宮田茂雄、須藤貴史、齋藤繁、山田一夫、一谷幸男、梶田裕貴、大城朝一、虫明元、渡邊雅彦、宮坂佳樹、真下知士、安田浩樹、柳川右千夫
- Organizer
  第41回日本生物学的精神医学会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 乳がんモデルラットにおいてBrca1遺伝子変異が放射線誘発乳がんリスクに及ぼす影響2019
- Author(s)
  久保田　丈, 今岡　達彦, 西村　まゆみ, 臺野　和広, 宮坂　佳樹, 真下　知士, 井上　一雅, 福士　政広, 島田　義也, 柿沼　志津子
- Organizer
  令和元年度若手放射線生物学研究会専門研究会
- Data Source
  KAKENHI-PROJECT-15H02824
[Presentation] ゲノム編集と重症免疫不全ラットの開発について2019
- Author(s)
  真下知士
- Organizer
  第90回信州実験動物研究会秋期勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 新規ゲノム編集技術CRISPR/Cas3の概要2019
- Author(s)
  真下知士
- Organizer
  武田薬品湘南研究所
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集による疾患モデルの作製2019
- Author(s)
  真下知士
- Organizer
  第53回日本実験動物技術者協会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ChIP-seqを利用したDNA損傷およびヌクレオチド除去修復のモニタリング.2019
- Author(s)
  原雄一郎, 中沢由華, 岡泰由, 小峯起, Diana van den Heuvel, 郭朝万, 大学保一, 磯野真由, 何予希, 嶋田繭子, 加藤香奈, 賈楠, 橋下悟, 小谷祐子, 三好由夏, 田中都, 祖父江顕, 光武範吏, 菅波孝祥, 増田章男, 大野欽司, 中田慎一郎, 真下知士, 山中宏二, Martijn S. Luijsterburg, 荻朋男.
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H00783
[Presentation] 先端モデル動物とゲノム編集2019
- Author(s)
  真下知士
- Organizer
  東京大学医科学研究所
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] Brca1遺伝子改変ラットにおける放射線誘発乳がんの解析2019
- Author(s)
  久保田　丈, 今岡　達彦, 西村　まゆみ, 臺野　和広, 宮坂　佳樹, 真下　知士, 井上　一雅, 福士　政広, 島田　義也, 柿沼　志津子
- Organizer
  第13回日本診療放射線学教育学会学術集会
- Data Source
  KAKENHI-PROJECT-15H02824
[Presentation] トランスレーショナルリサーチにおけるゲノム編集への期待と限界2019
- Author(s)
  真下知士
- Organizer
  塩見雅志准教授退職記念祝賀会・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-mediated genome engineering and its application in animal models2019
- Author(s)
  Tomoji Mashimo
- Organizer
  22nd US-Japan Cellular and Gene Therapy Conference, Adeno-associated Virus-Mediated Gene Therapy Gene Therapy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] Brca1遺伝子改変動物モデルにおける放射線誘発乳がんの解析2019
- Author(s)
  久保田　丈, 今岡　達彦, 西村　まゆみ, 臺野　和広, 宮坂　佳樹, 真下　知士, 井上　一雅, 福士　政広, 島田　義也, 柿沼　志津子
- Organizer
  2019年度関東甲信越診療放射線技師学術大会
- Data Source
  KAKENHI-PROJECT-15H02824
[Presentation] ゲノム編集による疾患モデルの作製2019
- Author(s)
  真下知士
- Organizer
  第53回日本実験動物技術者協会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集を使った超簡単ノックインマウスの作成2019
- Author(s)
  真下知士
- Organizer
  がん研究ツール最前線2019
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 新規ゲノム編集ツール、遺伝子改変ラット、ヒト化動物の未来2019
- Author(s)
  真下知士
- Organizer
  第144回関西実験動物研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] A novel model rat of chronic kidney disease2019
- Author(s)
  Ohmori Iori, Mashimo Tomoji, Ouchida Mamoru, Toyokuni Shinya
- Organizer
  The 9th Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Phenotype characterization of GAD65/GAD67 double mutant rats2019
- Author(s)
  姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、柴崎貢志、石崎泰樹、宮坂佳樹、真下知士、柳川右千夫
- Organizer
  日本ゲノム編集学会第4回大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] トランスレーショナルリサーチにおけるゲノム編集への期待と限界2019
- Author(s)
  真下知士
- Organizer
  塩見雅志准教授退職記念祝賀会・シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] 新規ゲノム編集ツール、遺伝子改変ラット、ヒト化動物の未来2019
- Author(s)
  真下知士
- Organizer
  第144回関西実験動物研究会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集で作製したグルタミン酸脱炭酸酵素ノックアウトラットの表現型2018
- Author(s)
  柳川右千夫、藤原和之、柿崎利和、宮田茂雄、渡辺雅彦、大城朝一、虫明元、宮坂佳樹、真下知士
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集の最新技術動向2018
- Author(s)
  真下知士
- Organizer
  2018年度第3回「ヒトゲノム研究倫理を考える会」
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 受精卵におけるゲノム編集の潮流2018
- Author(s)
  真下知士
- Organizer
  日本ゲノム編集学会第3回大会ランチョンセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-mediated genome engineering in mice, rats, and rabbits.2018
- Author(s)
  Mashimo T
- Organizer
  The 9th Takeda Science Foundation Symposium on PharmaSciences, Center for Learning and Innovation (CLI), Takeda Pharmaceutical Company Ltd. Osaka, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術によるモデル動物の作製2018
- Author(s)
  真下知士
- Organizer
  日本実験動物技術者協会関西支部平成29年度春季大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集の最新技術概要2018
- Author(s)
  真下知士
- Organizer
  日本高血圧学会・高血圧関連疾患モデル学会合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集によるヒト化動物の作製2018
- Author(s)
  真下知士
- Organizer
  公益財団法人実験動物中央研究所CIEA
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] マウス・ラットにおける新規ゲノム編集技術の開発2018
- Author(s)
  真下知士
- Organizer
  JST-OPERA産学共創会議（第2回）
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集CRISPR/Cas9による新規モデル動物の開発2018
- Author(s)
  真下知士
- Organizer
  第20回教育研究推進センター講演会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] An overview of recent genome editing technologies2018
- Author(s)
  真下知士
- Organizer
  第77回日本癌学会学術総会、シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集ラットの作製2018
- Author(s)
  真下知士
- Organizer
  一般財団法人動物繁殖研究所
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] マウス・ラットにおけるゲノム編集技術の現状2018
- Author(s)
  吉見一人、真下知士
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集CRISPR/Cas9システムの今とこれから2018
- Author(s)
  真下　知士
- Organizer
  平成29年度大阪府高校生物教育研究会
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] マウス・ラットモデル作成の新展開2018
- Author(s)
  真下知士
- Organizer
  第41回日本分子生物学会年会バイオテクノロジーセミナーアプライドステムセル
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集による遺伝子改変動物の作製技術2018
- Author(s)
  真下知士
- Organizer
  国立長寿医療研究センターNCGGセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] マウス・ラットモデル作成の新展開2018
- Author(s)
  真下知士
- Organizer
  第41回日本分子生物学会年会バイオテクノロジーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集の最新技術動向2018
- Author(s)
  真下知士
- Organizer
  第24回国立大学法人動物実験施設協議会高度技術研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18KK0307
[Presentation] ゲノム編集技術によるモデル動物の作製2018
- Author(s)
  真下　知士
- Organizer
  日本実験動物技術者協会関西支部平成29年度春季大会
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集とその活用2018
- Author(s)
  真下知士
- Organizer
  2018年度西宮市ライフサイエンスセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集技術と新規モデル動物2018
- Author(s)
  真下知士
- Organizer
  先導的学際研究機構創薬サイエンス部門シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 新しいヒト化動物の創成　ゲノム編集の成果と展望2018
- Author(s)
  真下　知士
- Organizer
  平成29年度生命科学連携推進協議会市民公開シンポジウム平成29年度生命科学連携推進協議会市民公開シンポジウムグランフロント大阪コングレコンベンションセンター、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集の新展開2018
- Author(s)
  真下知士
- Organizer
  福島県立医科大学生体情報伝達研究所第68回Molecular Medicine Seminar
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] GAD65/67二重変異ラットの作製と解析2018
- Author(s)
  姜玮茹、柿崎利和、藤原和之、宮田茂雄、張月、須藤貴史、加藤大樹、齋藤繁、宮坂佳樹、真下知士、柳川右千夫
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集の最新技術動向2018
- Author(s)
  真下知士
- Organizer
  第24回国立大学法人動物実験施設協議会高度技術研修会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] CRISPR-Casシステムを用いたヒト細胞におけるゲノム編集2018
- Author(s)
  真下知士森坂広行、吉見一人、竹田潤二
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] ゲノム編集の最新技術概要2018
- Author(s)
  真下知士
- Organizer
  科学委員会ゲノム編集専門部会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03974
[Presentation] 動物実験施設におけるゲノム編集技術の活用2017
- Author(s)
  真下知士
- Organizer
  第43回国立大学法人動物実験施設協議会総会技術職員懇談会、香川
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated genome engineering in rats.2017
- Author(s)
  Mashimo T
- Organizer
  dinburgh Rat Meeting, SCRM building, The University of Edinburgh, Edinburgh, UK,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集－その可能性の先にあるものとは2017
- Author(s)
  真下知士
- Organizer
  ナレッジキャピタル超学校 MOU-ICHIDO 自分進化論
- Place of Presentation
  グランフロント大阪北館ナレッジキャピタル1F（大阪市）
- Year and Date
  2017-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] Efficient generation of conditional knockout mice by CLICK2017
- Author(s)
  Mashimo T
- Organizer
  INFRAFRONTIER/IMPC Stakeholder Meeting, Royal Olympic Hotel, Athens, Greece,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated genome engineering in animals.2017
- Author(s)
  Mashimo T
- Organizer
  International Conference of the Genetics Society of Korea (ICGSK) 2017,
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集による疾患モデル動物の開発2017
- Author(s)
  真下知士
- Organizer
  第57回日本先天異常学会第6回日本DOHaD学会合同学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集による疾患モデル動物の開発2017
- Author(s)
  真下知士
- Organizer
  第57回日本先天異常学会・第6回日本DOHaD学会合同学術集会、早稲田大学理工学術院西早稲田キャンパス、東京
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] フランス留学から始まったゲノム編集研究！？2017
- Author(s)
  真下　知士
- Organizer
  第187回日仏生物学会、京都府立医科大学、京都
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 動物実験施設におけるゲノム編集技術の活用2017
- Author(s)
  真下知士
- Organizer
  第60回日本神経化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] Highly efficient genome editing in embryos using the Super Electroporator NEPA212017
- Author(s)
  Mashimo T
- Organizer
  The 4th World Congress of Reproductive Biology 2017 (WCRB 2017), Okinawa, Japan
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] マウス・ラットにおける新規ゲノム編集技術の開発2017
- Author(s)
  真下知士
- Organizer
  JST-OPERA「ゲノム編集による革新的な有用細胞・生物作成技術の創出」キックオフシンポジウム（招待講演）
- Place of Presentation
  2017年3月17日ホテルグランヴィア広島4F（広島市）
- Year and Date
  2017-03-17
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated genome engineering in animals.2017
- Author(s)
  真下知士
- Organizer
  International Conference of the Genetics Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 動物実験施設におけるゲノム編集技術の活用2017
- Author(s)
  真下知士
- Organizer
  第60回日本神経化学会大会、仙台国際センター、仙台
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 動物実験施設におけるゲノム編集技術の活用2017
- Author(s)
  真下知士
- Organizer
  第43回国立大学法人動物実験施設協議会総会技術職員懇談会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] CRISPR-mediated genome engineering in rats.2017
- Author(s)
  真下知士
- Organizer
  Edinburgh Rat Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集による再生医療モデル動物の開発2017
- Author(s)
  真下知士
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2017-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated genome engineering in zygotes.2017
- Author(s)
  Mashimo T
- Organizer
  14th Transgenic Technology Meeting, The International Society for Transgenic Technologies (ISTT), Snowbird Resort, Salt Lake City, Utah, USA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] Efficient generation of conditional knockout mice by CLICK2017
- Author(s)
  Mashimo T
- Organizer
  9th Workshop on Innovative Mouse Models, IMM2017, Leiden, The Netherlands
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術によるモデル動物開発研究2017
- Author(s)
  真下　知士
- Organizer
  先端医療技術開発センターシンポジウム、自治医科大学、栃木
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated Genome Engineering in Mice, Rats, and Rabbits2017
- Author(s)
  Mashimo T
- Organizer
  24th Asia Pacific Cancer Conference (APCC), Seoul, Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR-mediated genome ongineering in zygotes.2017
- Author(s)
  真下知士
- Organizer
  14th Transgenic Technology Meeting, The International Society for Transgenic Technologies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ラットの遺伝子改変2017
- Author(s)
  真下　知士
- Organizer
  017年度遺伝研研究会、国立遺伝学研究所、三島、静岡
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] Highly efficient genomo editing in embryos using the super electroporator NEPA21.2017
- Author(s)
  真下知士
- Organizer
  The 4th World Congress of Reproductive Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ラットの遺伝子改変2017
- Author(s)
  真下知士
- Organizer
  2017年度遺伝研研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] ゲノム編集技術と新規モデル動物2017
- Author(s)
  真下　知士
- Organizer
  先導的学際研究機構創薬サイエンス部門シンポジウム、グランフロント大阪北館タワー、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 次世代ゲノム編集ラットの作製支援事業2017
- Author(s)
  真下知士
- Organizer
  第３回KBRPワークショップ
- Place of Presentation
  2017年3月17日熊本大学生命資源研究支援センター（熊本市）
- Year and Date
  2017-03-10
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術によるモデル動物開発研究2017
- Author(s)
  真下知士
- Organizer
  先端医療技術開発センターシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H06276
[Presentation] 哺乳動物におけるゲノム編集技術の開発2016
- Author(s)
  真下知士
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  メルパルク京都（京都市）
- Year and Date
  2016-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] モデル動物作製のための最先端CRISPR技術2016
- Author(s)
  真下知士
- Organizer
  BioJapan 2016 World Business Forum
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9によるゲノム編集動物の超簡単作製法2016
- Author(s)
  真下知士
- Organizer
  ゲノム編集 2016 ～ Genome Editing 2016の可能性～
- Place of Presentation
  中央大学駿河台記念館（東京都千代田区））
- Year and Date
  2016-05-26
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術の基礎と応用～ゲノム編集動物の現状と可能性・克服すべき課題～2016
- Author(s)
  真下知士
- Organizer
  情報機構セミナー
- Place of Presentation
  [東京・大井町]きゅりあん4階（東京大井町）
- Year and Date
  2016-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術によるモデル動物の作製支援事業2016
- Author(s)
  真下知士
- Organizer
  大阪大学大学院医学系研究科共同研附属ゲノム編集センター第1回セミナー
- Place of Presentation
  大阪大学大学院医学系研究科臨床研究棟3階
- Year and Date
  2016-12-14
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ssODN-mediated knock-in with CRISPR-Cas for large genomic regions.2016
- Author(s)
  真下知士
- Organizer
  University of Copenhagen PhD course “Genome Editing using CRISPR/Cas9
- Place of Presentation
  Copenhagen Biocenter（Copenhagen Denmark）
- Year and Date
  2016-09-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9と長鎖一本鎖DNAによる超簡単ノックイン法2016
- Author(s)
  真下知士
- Organizer
  第38回日本分子生物学会バイオテクノロジーセミナー
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集とは何か？遺伝子操作の最新事情2016
- Author(s)
  真下知士
- Organizer
  第96回北天満サイエンスカフェ
- Place of Presentation
  天五中崎通商店街路上（大阪市北区）
- Year and Date
  2016-05-22
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 哺乳動物におけるゲノム編集基盤技術の開発2016
- Author(s)
  真下知士
- Organizer
  第１０回家畜ＤＮＡ西郷シンポジウム
- Place of Presentation
  (独)家畜改良センター講堂（福島県西白河郡）
- Year and Date
  2016-09-28
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集とヒト化動物2016
- Author(s)
  真下知士
- Organizer
  大阪大学未来戦略機構第六部門創薬基盤科学研究部門シンポジウム
- Place of Presentation
  大阪大学銀杏会館（大阪府吹田市）
- Year and Date
  2016-01-15
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ラットにおけるゲノム編集技術の最前線2016
- Author(s)
  真下知士
- Organizer
  群馬大学遺伝発達行動学セミナー『ラットを用いた医学生命科学研究―最近の知見』
- Place of Presentation
  群馬大学基礎大学院講義室（群馬県前橋市）
- Year and Date
  2016-09-15
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9による哺乳動物でのゲノム編集2015
- Author(s)
  真下知士
- Organizer
  第127回関西実験動物研究会
- Place of Presentation
  大阪大学銀杏会館（大阪府吹田市）
- Year and Date
  2015-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 生物種を超えた表現型情報統合のためのデータ作成2015
- Author(s)
  高月照江、矢田有加里、斎藤実香子、高田豊行、真下知士、成瀬清、若菜茂晴、田中信彦、桝屋啓志
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2015-06-08
- Data Source
  KAKENHI-PROJECT-15H02755
[Presentation] ゲノム編集技術をもちいたゲノム改変ラット2015
- Author(s)
  真下知士
- Organizer
  第一回「ゲノム編集技術」に関する戦略ワークショップ
- Place of Presentation
  JST東京本部別館（東京都千代田区）
- Year and Date
  2015-07-20
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Casシステムによるノックインラットの作製2015
- Author(s)
  真下知士
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ（京都市南区）
- Year and Date
  2015-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9 with ssODNs enables gene knock-in and replacement of large genomic regions in rats.2015
- Author(s)
  Mashimo T
- Organizer
  Nara Kasugano International Forum IRAKA
- Place of Presentation
  奈良県奈良市
- Year and Date
  2015-11-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 疾患モデル動物の作製と利用2015
- Author(s)
  真下知士
- Organizer
  第40回懇話会、日本実験動物技術者協会関東支部
- Place of Presentation
  川崎市産業振興会館
- Year and Date
  2015-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集とは2015
- Author(s)
  真下知士
- Organizer
  ヒトゲノム解析研究倫理審査を考える会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-08-09
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9による効率的なモデル動物の開発2015
- Author(s)
  真下知士
- Organizer
  第51回高血圧関連疾患モデル学会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Casシステムを使った遺伝子組換え2015
- Author(s)
  真下知士
- Organizer
  平成27年度共同研機器分析セミナー
- Place of Presentation
  大阪学院医系研究科附属共同研究実習センター（大阪府吹田市）
- Year and Date
  2015-04-15
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術の最前線：CRISPRによるヒト疾患モデル動物の開発2015
- Author(s)
  真下知士
- Organizer
  第86回未来医療セミナー
- Place of Presentation
  大阪大学医学部講義棟C講堂
- Year and Date
  2015-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Cas9 with ssODNs enables gene knock-in and replacement of large genomic regions in rats.2015
- Author(s)
  Tomoji Mashimo, Kazuto Yoshimi, Yayoi Kunihiro, Takehito Kaneko, Birger Voigt
- Organizer
  Rat Genomics & Models
- Place of Presentation
  Cold Spring Harbor Laboratory (New York, USA)
- Year and Date
  2015-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] CRISPR/Casシステムを使った遺伝子改変動物の作製2015
- Author(s)
  真下知士
- Organizer
  平成27年度和光純薬工業代理店講習会
- Place of Presentation
  和光純薬工業株式会社（大阪市中央区）
- Year and Date
  2015-05-12
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ゲノム編集技術がもたらす実験動物学の新しい潮流2015
- Author(s)
  真下知士
- Organizer
  東京都健康長寿医療センター研究所実験動物慰霊祭
- Place of Presentation
  東京都健康長寿医療センター
- Year and Date
  2015-02-09
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] Production of knockout rats by using zinc finger nucleases and TAL effector nucleases2014
- Author(s)
  Takehito Kaneko, Tomoji Mashimo
- Organizer
  40th annual conference International Embryo Transfer Sciety
- Place of Presentation
  John Ascuaga’s Nugget Hotel, Navada, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] CRISPR/Casシステム：自由自在な遺伝子改変技術2014
- Author(s)
  真下知士
- Organizer
  島根大学医学部セミナー
- Place of Presentation
  島根大学医学部
- Year and Date
  2014-04-04
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] HR/Izm全ゲノムシーケンスでの補体C3構造とジンクフィンガーヌクレアーゼ(ZFN)法によるC3ノックアウトSHR/Izmの病態解析2014
- Author(s)
  根岸英理子、福田　昇、片川まゆみ、上野高浩、相馬正義、真下知士
- Organizer
  第50回　高血圧関連疾患モデル学会
- Place of Presentation
  和歌山
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] 補体C3は高血圧自然発症ラット(SHR)の間葉系組織を脱分化し組織RA系を介して高血圧を引き起こす2014
- Author(s)
  根岸英理子、福田　昇、片川まゆみ、上野高浩、小松一俊、相馬正義、真下知士
- Organizer
  第18回　日本心血管内分泌代謝学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-21
- Data Source
  KAKENHI-PROJECT-24591242
[Presentation] Production of knockout rats by using zinc finger nucleases and TAL effector nucleases2014
- Author(s)
  Takehito Kaneko, Tomoji Mashimo
- Organizer
  40th annual conference International Embryo Transfer Sciety (IETS)
- Place of Presentation
  Nevada, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Efficient gene targeting with engineered nucleases in rats2013
- Author(s)
  Tomoji Mashimo, Kazuto Yoshimi, Takehito Kaneko
- Organizer
  The 5th EMBO meeting
- Place of Presentation
  Amsterdam, Netherlands
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] The third term of the national bioresource project - rat in Japan2013
- Author(s)
  Birger Voigt, Tomoji Mashimo, Takehito Kaneko, Hiroaki Taketsuru, Kazuto Yoshimi, Yuki Neoda, Zohg-hu Cui, Yayoi Kunihiro, Kumi Kosako, Kosuke Hattori, Machiko Hayashi, Ken-ichi Yamasaki, Satoshi Nakanishi, Tadao Serikawa, Takashi Kuramoto
- Organizer
  Rat genomics & models
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Knockout and knock-in mutation for rat albino gene generated by CRISPR/Cas2013
- Author(s)
  Kazuto Yoshimi, Takehito Kaneko, Tomoji Mashimo
- Organizer
  Rat genomics & models
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] TALエフェクターヌクレアーゼ（TALENs）を用いたノックアウトラット作製技術2013
- Author(s)
  金子武人、佐久間哲史、山本卓、芹川忠夫、真下知士
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場（つくば市）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Gene targeting technologies in rats : ZFN, TALEN, and CRISPR2013
- Author(s)
  Tomoji Mashimo, Kazuto Yoshimi, Takehito Kaneko, Tadao Serikawa
- Organizer
  Rat genomics & models
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 実験用ラットにおけるゲノム編集技術 : ZFN、TALENそしてCRISPRへ2013
- Author(s)
  真下知士、吉見一人、金子武人
- Organizer
  第36回日本分子生物学会年会シンポジウムゲノム編集研究の新展開
- Place of Presentation
  神戸ポートアイランド、兵庫県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] CRISPR/Casを用いたSNP特異的遺伝子改変ラットの作製2013
- Author(s)
  吉見一人、金子武人、芹川忠夫、真下知士
- Organizer
  第3回ゲノム編集研究会
- Place of Presentation
  広島大学理学部、広島県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 実験用ラットにおけるゲノム編集技術：ZFN、TALENそしてCRISPRへ2013
- Author(s)
  真下知士、吉見一人、金子武人
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（神戸市）
- Invited
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 遺伝子改変ラットの開発研究2013
- Author(s)
  真下知士
- Organizer
  第6回ラットリソースリサーチ研究会・第1回実験動物科学シンポジウム
- Place of Presentation
  京都
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] マウス・ラット表現型から疾患を推論するソフトウェアの開発2013
- Author(s)
  桝屋啓志, 古崎晃司, 高田豊行, 真下知士, 若菜茂晴, 大江和彦, 溝口理一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば
- Year and Date
  2013-05-15
- Data Source
  KAKENHI-PROJECT-23300161
[Presentation] The third term of the national bioresource project–rat in Japan2013
- Author(s)
  Birger Voigt, Tomoji Mashimo, Takehito Kaneko, Hiroaki Taketsuru, Kazuto Yoshimi, Yuki Neoda, Zohg-hu Cui, Yayoi Kunihiro, Kumi Kosako, Kosuke Hattori, Machiko Hayashi, Ken-ichi Yamasaki, Satoshi Nakanishi, Tadao Serikawa, Takashi Kuramoto
- Organizer
  Rat genomics & models
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] ZFNおよびTALENを用いたノックアウトラットの作製2013
- Author(s)
  金子武人、真下知士
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  東京農工大学農学部（東京都）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 実験用ラットにおけるゲノム編集技術 : ZFN, TALENそしてCRISPR2013
- Author(s)
  真下知士、吉見一人、金子武人、芹川忠夫
- Organizer
  第3回ゲノム編集研究会
- Place of Presentation
  広島大学理学部、広島県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Gene targeting technologies in rats: ZFN, TALEN, and CRISPR2013
- Author(s)
  Tomoji Mashimo, Kazuto Yoshimi, Takehito Kaneko, Tadao Serikawa
- Organizer
  Rat genomics & models
- Place of Presentation
  Cold Spring Harbor Laboratory, New York, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] TALエフェクターヌクレアーゼ(TALENs)を用いたノックアウトラット作製技術2013
- Author(s)
  金子武人、佐久間哲史、山本卓、芹川忠夫、真下知士
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場、茨城県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Knockout and knock-in mutation for rat albino gene generated by CRISPR/Cas2013
- Author(s)
  Kazuto Yoshimi, Takehito Kaneko, Tomoji Mashimo
- Organizer
  Rat genomics & models
- Place of Presentation
  New York, USA
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] ZFNおよびTALENを用いたノックアウトラットの作製2013
- Author(s)
  金子武人、真下知士
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  東京農工大学農学部、東京都
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] ラットにおける遺伝子改変技術の新展開2013
- Author(s)
  芹川忠夫、金子武人、佐久間哲史、山本卓、真下知士
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場、福岡県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 実験用ラットにおけるゲノム編集技術：ZFN, TALENそしてCRISPR2013
- Author(s)
  真下知士、吉見一人、金子武人、芹川忠夫
- Organizer
  第3回ゲノム編集研究会
- Place of Presentation
  広島大学理学部（広島県）
- Invited
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] CRISPR/Casを用いたSNP特異的遺伝子改変ラットの作製2013
- Author(s)
  吉見一人、金子武人、芹川忠夫、真下知士
- Organizer
  第3回ゲノム編集研究会
- Place of Presentation
  広島大学理学部（広島県）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] TALENを用いた遺伝子改変ラットの効率的な作製方法2012
- Author(s)
  真下知士、金子武人、国広弥生、芹川忠夫
- Organizer
  第2回ゲノム編集研究会
- Place of Presentation
  岡崎コンファレンスセンター、愛知県
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] ラットにおける遺伝子改変技術の新展開2012
- Author(s)
  芹川忠夫、金子武人、佐久間哲史、山本卓、真下知士
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Efficient gene targeting by TAL effector nucleases in rats2012
- Author(s)
  Tomoji Mashimo, Takehito Kaneko, Tetsushi Sakuma, Yayoi Kunihiro, Birger Voigt, Takashi Yamamoto, Tadao Serikawa
- Organizer
  Rat Genome and Models
- Place of Presentation
  ケンブリッジ（イギリス）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 重症免疫不全SCIDラットとその応用研究について2012
- Author(s)
  真下知士
- Organizer
  第5回ラットリソースリサーチ研究会
- Place of Presentation
  京都、京都大学百周年時計台記念館
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Efficient gene targeting by TAL effector nucleases in rats2012
- Author(s)
  Tomoji Mashimo, Takehito Kaneko, Tetsushi Sakuma, Yayoi Kunihiro, Birger Voigt, Takashi Yamamoto, Tadao Serikawa
- Organizer
  Rat Genome and Models, A Welcome Trust Scientific Conference
- Place of Presentation
  Cambridge, UK
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] ラットを中心とした遺伝子改変動物研究の現状2012
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡、福岡国際会議場
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes.2012
- Author(s)
  Tomoji Mashimo, Takehito Kaneko, Tetsushi Sakuma, Junya Kobayashi, Yayoi Kunihiro, Birger Voigt, Takashi Yamamoto, Tadao Serikawa
- Organizer
  Rat Genome and Models
- Place of Presentation
  ケンブリッジ（イギリス）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 人工ヌクレアーゼTALENによるノックアウトラットの作製2012
- Author(s)
  真下知士、金子武人、国広弥生、佐久間哲史、山本卓、芹川忠夫
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府国際コンベンションセンター、大分県
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 人工ヌクレアーゼTALENによるノックアウトラットの作製2012
- Author(s)
  真下知士、金子武人、国広弥生、佐久間哲史、山本卓、芹川忠夫
- Organizer
  日本実験動物科学・技術九州2012
- Place of Presentation
  別府国際コンベンションセンター（大分県）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] 人工ヌクレアーゼZFN/TALENによる遺伝子改変ラットの作製2012
- Author(s)
  真下知士, 他2名
- Organizer
  第1回ゲノム編集研究会
- Place of Presentation
  広島、広島大学理学部
- Year and Date
  2012-02-03
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] LGI1 変異ラット音刺激誘発けいれんモデルにおけるc-Fos 免疫染色による解析2012
- Author(s)
  麓直浩、真下知士、増井淳、水口祐登、南本翔子、石田紗恵子、池田昭夫、高橋良輔、芹川忠夫、大野行弘
- Organizer
  第8回日本てんかん学会近畿地方会
- Place of Presentation
  大阪、薬業年金会館
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes2012
- Author(s)
  Tomoji Mashimo, Takehito Kaneko, Tetsushi Sakuma, Junya Kobayashi, Yayoi Kunihiro, Birger Voigt, Takashi Yamamoto, Tadao Serikawa
- Organizer
  Techniques and Procedures for Rat Gene Targeting, Reproduction, and Cryopreservation
- Place of Presentation
  Cambridge, UK
- Year and Date
  2012-12-03
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] Zinc-finger nucleases (ZFNs) as gene-targeting technology in animals2011
- Author(s)
  真下知士
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜、パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラット遺伝子改変技術の進歩:ヒト化ラットの開発に向けて2011
- Author(s)
  真下知士
- Organizer
  AK拠点招聘セミナー
- Place of Presentation
  京都、京都大学医学研究科
- Year and Date
  2011-04-20
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Creation of Knockout Rats Using Zinc-Finger Nucleases2011
- Author(s)
  真下知士
- Organizer
  Australasian Gene Therapy Society Meeting
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラット遺伝子改変技術のめざましい進歩2011
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第47回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Zinc-finger nucleases (ZFNs) as gene-targeting technology in animals2011
- Author(s)
  真下知士
- Organizer
  Queensland Institute of Medical Research
- Place of Presentation
  Brisbane, New Zealand
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] SCID rats as an animal model for preclinical xenotransplantation2011
- Author(s)
  真下知士, 他14名
- Organizer
  The 2011 meeting on Rat Genomics & Models
- Place of Presentation
  Cold Spring Harbor, New York, USA
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ZFNによる遺伝子改変ラットの作製法2011
- Author(s)
  真下知士
- Organizer
  自然科学研究機構・基礎生物学研究所共同利用共同研究・研究会
- Place of Presentation
  岡崎、基礎生物学研究所
- Year and Date
  2011-07-11
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラット遺伝子改変技術のめざましい進歩2011
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第47回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  札幌、北海道大学医学研究科
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の進歩:再生医療に役立つモデル動物2011
- Author(s)
  真下知士
- Organizer
  第42回再生医療・臓器再建医学コースミーティング
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-02-18
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ジンクフィンガーヌクレアーゼを利用した遺伝子改変動物の作製2011
- Author(s)
  真下知士
- Organizer
  第58回日本実験動物学会総会
- Place of Presentation
  東京、タワーホール船堀
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 遺伝子改変動物作製技術の新しい展開2011
- Author(s)
  真下知士
- Organizer
  シグマアルドリッチライフサイエンスセミナー2011
- Place of Presentation
  大阪、大阪ハイテクノロジー専門学校
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ジンクフィンガーヌクレアーゼにより作製したIl2rgノックアウト(XSCID)ラット2010
- Author(s)
  真下知士
- Organizer
  第84回彩都バイオサイエンスセミナー
- Place of Presentation
  茨木(招待講演)
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] KURMA - Kyoto University Rat Mutant Archive2010
- Author(s)
  Mashimo T, Takizawa A, Voigt B, Kuramoto T, Serikawa T
- Organizer
  EURAT Meeting 2010
- Place of Presentation
  Berlin, Germany
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Creation of Knockout Rats : A New Paradigm for Target Validation and Preclinical Development.2010
- Author(s)
 Mashimo T
- Organizer
 22^<nd> Annual Meeting of the KSMCB
- Place of Presentation
 Seoul, Korea(招待講演)
- Year and Date
 2010-10-07
- Data Source
 KAKENHI-PROJECT-21680037
[Presentation] Genetically modified rat models of human epilepsy produced by a gene-targeting approach2010
- Author(s)
  Mashimo T
- Organizer
  Hopital de la Pitie-Salpetriere
- Place of Presentation
  Paris
- Year and Date
  2010-10-25
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Creation of Knockout Rats: A New Paradigm for Target Validation and Preclinical Development2010
- Author(s)
  Mashimo T
- Organizer
  22ndAnnual Meeting of the KSMCB
- Place of Presentation
  Seoul, Korea
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Recent progress of gene-targeting technologies in rats: ENU mutagenesis and zinc finger nucleases2010
- Author(s)
  Mashimo T
- Organizer
  14thinternational SHR symposium
- Place of Presentation
  Montreal, Canada
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Pharma cological analysis of the hyper the rmia-induced seizure-susceptible(Hiss) rats, a novel rat model of febrile seizure2010
- Author(s)
  Ohno Y, Ishihara S, Sofue N, Mashimo T, Sasa M, Serikawa T
- Organizer
  The XVIIIth International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Scn1a Mutant Rats Display Ataxia and Memory Deficit2010
- Author(s)
  Liu S, Ohmori I, Hayashi K, Nishiki T, Mashimo T, 以下2人略
- Organizer
  第87回日本生理学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21390312
[Presentation] 遺伝子組み換えモデル動物作成の新技術2010
- Author(s)
  真下知士
- Organizer
  京都大学大学院医学研究科神経科学ミニコース
- Place of Presentation
  京都
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発2010
- Author(s)
  真下知士
- Organizer
  BioJapan2010 アカデミックシーズ発表会
- Place of Presentation
  横浜
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Recent progress of gene-targeting technologies in rats : ENU mutagenesis and zinc forger nucleases.2010
- Author(s)
 Mashimo T
- Organizer
 14^<th> international SHR symposium
- Place of Presentation
 Montreal, Canada(招待講演)
- Year and Date
 2010-09-24
- Data Source
 KAKENHI-PROJECT-21680037
[Presentation] ジンクフィンガーヌクレアーゼ(ZFN)により作製したX連鎖重症複合免疫不全(XSCID)ラット2010
- Author(s)
  真下知士
- Organizer
  iPS・ES・体性幹細胞Forum2010
- Place of Presentation
  東京
- Year and Date
  2010-06-29
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Scn1a遺伝子変異ラットを用いた抗てんかん薬の熱性けいれん抑制効果2010
- Author(s)
  林桂一郎, 大守伊織, 西木禎一, 真下知士, 以下2人略
- Organizer
  第87回日本生理学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21390312
[Presentation] 遺伝子機能解析の新展開:ノックアウトラットの作製法2010
- Author(s)
  真下知士
- Organizer
  高血圧学会・高血圧関連疾患モデル学会合同シンポジウム
- Place of Presentation
  博多
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Scn1a変異ラットにおける反復熱性けいれんが脳機能に及ぼす影響2010
- Author(s)
  劉素梅, 大守伊織, 林桂一郎, 真下知士, 以下2人略
- Organizer
  てんかん学会中国四国地方会
- Place of Presentation
  山口
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21390312
[Presentation] KURMA-Kyoto University Rat Mutant Archive.2010
- Author(s)
  Mashimo T, (他4人)
- Organizer
  EURAT Meeting 2010
- Place of Presentation
  Berlin, Germany
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] SCID rats : targeted disruption of the DNA-PKcs gene via zinc finger nucleases.2010
- Author(s)
  Mashimo T, (他9人)
- Organizer
  The XVIIIth International Workshop on Genetic Systems in the Rat
- Place of Presentation
  Kyoto
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発2010
- Author(s)
  真下知士
- Organizer
  京都大学「医学領域」産学連携推進機構/(社)芝蘭会平成22年度第1回産学情報交流会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Severe combined immunodeficiency (SCID) rats generated by zinc finger nuclease technology.2010
- Author(s)
 Mashimo T, (他6人)
- Organizer
 24^<th> International Mammalian Genome Conference
- Place of Presentation
 Crete, Greece
- Year and Date
 2010-10-18
- Data Source
 KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発:ENU ミュータジェネシスとジンクフィンガーヌクレアーゼ2010
- Author(s)
  真下知士
- Organizer
  筑波大学人間総合科学研究科医学セミナー
- Place of Presentation
  筑波
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発2010
- Author(s)
  真下知士
- Organizer
  東海医学会講演会
- Place of Presentation
  伊勢原
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発:ENUミュータジェネシスとジンクフィンガーヌクレアーゼ2010
- Author(s)
  真下知士
- Organizer
  筑波大学人間総合科学研究科医学セミナー
- Place of Presentation
  筑波(招待講演)
- Year and Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発」京都大学「医学領域」産学連携推進機構/(社)芝蘭会2010
- Author(s)
  真下知士
- Organizer
  平成 22 年度第1回産学情報交流会
- Place of Presentation
  京都
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 遺伝子組み換えモデル動物作成の新技術2010
- Author(s)
  真下知士
- Organizer
  京都大学大学院医学研究科神経科学ミニコース
- Place of Presentation
  京都(招待講演)
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ジンクフィンガーヌクレアーゼにより作製したX連鎖重症複合免疫不全ラット2010
- Author(s)
  真下知士, (他7人)
- Organizer
  第57回日本実験動物学会総会
- Place of Presentation
  京都
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術と表現型解析によるゲノム機能解析の現状2010
- Author(s)
  真下知士
- Organizer
  日本遺伝学会第82回大会
- Place of Presentation
  札幌
- Year and Date
  2010-09-20
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 遺伝子機能解析の新展開:ノックアウトラットの作製法2010
- Author(s)
  真下知士
- Organizer
  高血圧学会・高血圧関連疾患モデル学会合同シンポジウム
- Place of Presentation
  博多(招待講演)
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラットにおける遺伝子改変技術の開発2010
- Author(s)
  真下知士
- Organizer
  東海医学会講演会
- Place of Presentation
  伊勢原(招待講演)
- Year and Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 熱性けいれんモデルラットを用いた最適治療薬選択の試み2010
- Author(s)
  林桂一郎, 大守伊織, 西木禎一, 真下知士, 以下2人略
- Organizer
  てんかん学会中国四国地方会
- Place of Presentation
  山口
- Year and Date
  2010-02-13
- Data Source
  KAKENHI-PROJECT-21390312
[Presentation] ラットにおける遺伝子改変技術の開発2010
- Author(s)
  真下知士
- Organizer
  BioJapan2010 アカデミックシーズ発表会「京都大学」
- Place of Presentation
  横浜(招待講演)
- Year and Date
  2010-09-29
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、森泰生、芹川忠夫
- Organizer
  Neuro2009(第32回日本神経科学大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] Severe combined immunodeficiency (X-SCID) rats developed by targeted gene disruption using zinc-finger nucleases2009
- Author(s)
  Mashimo, et al., (他6人)
- Organizer
  The 2009 meeting on Rat Genomics & Models
- Place of Presentation
  Cold Spring Harbor, New York, USA
- Year and Date
  2009-12-04
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ラット ENU ミュータジェネシスプロジェクト2009
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、森泰生、芹川忠夫
- Organizer
  Neuro2009(第32 回日本神経科学大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] ラットENUミュータジェネシスプロジェクト2009
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第56回日本実験動物学会総会
- Place of Presentation
  大宮
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士, 大守伊織, 大内田守, 以下6人略
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-21390312
[Presentation] 熱刺激誘発けいれん感受性ラットの開発:新たな熱性けいれんモデルとして2009
- Author(s)
  真下知士、大守伊織、大内田守、大野行弘、鶴見東志子、三木崇史、若森実、森泰生、芹川忠夫
- Organizer
  Neuro2009(第32回日本神経科学大会)
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] チャネル病のモデル動物:電位依存性Na+チャネルNav1.1変異ラット2009
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第295回CBI学会研究講演会
- Place of Presentation
  東京
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] チャネル病のモデル動物:電位依存性Na+チャネルNav1. 1変異ラット2009
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第295回CBI学会研究講演会
- Place of Presentation
  東京
- Year and Date
  2009-04-03
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] ENUミュータジェネシスを利用した標的遺伝子変異ラットの作製2008
- Author(s)
  真下知士, 芹川忠夫
- Organizer
  第44回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  島根
- Year and Date
  2008-11-22
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスによる標的遺伝子変異ラットの開発2008
- Author(s)
  真下知士
- Organizer
  第1回ラットリソースリサーチ研究会
- Place of Presentation
  京都
- Year and Date
  2008-01-18
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスを利用した標的遺伝子変異ラットの作製2008
- Author(s)
  真下知士, ら
- Organizer
  第44回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  島根
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] TBLマウスの小脳性運動失調はユビキチンE3リガーゼのミスセンス変異に起因する2008
- Author(s)
  真下知士, ら
- Organizer
  第55回日本実験動物学会総会
- Place of Presentation
  仙台
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] ユビキチンE3リガーゼのミスセンス変異により小脳性運動失調をおこすマウス2008
- Author(s)
  真下知士, 他3人
- Organizer
  Neuro2008 (第31回神経科学大会)
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] KURMA : an ENU-induced mutant archive for gene-targeting in rats., Prasue, Czech Republic, Nov 2-5, 20082008
- Author(s)
  Mashimo T, et al., 他4人
- Organizer
  22nd International Mammalian Genome Conference
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスを利用した標的遺伝子変異ラツトの作製方法2008
- Author(s)
  真下知土
- Organizer
  第11回生命工学トレーニングコース
- Place of Presentation
  金沢
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] 標的遺伝子変異ラット作製のためのENUミュータントアーカイブ2008
- Author(s)
  真下知士
- Organizer
  高温耐性ラットシンポジウム2008
- Place of Presentation
  名古屋
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] KURMA : an ENU-induced mutant archive for gene-targeting in rats.2008
- Author(s)
  真下知士, ら
- Organizer
  The 22nd International Mammalian Genome Conference.
- Place of Presentation
  Prague, Czech Republic
- Year and Date
  2008-11-04
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] ユビキチンE3リガーゼのミスセンス変異により小脳性運動失調をおこすマウス2008
- Author(s)
  真下知士, ら
- Organizer
  Neuro2008 (第31回神経科学大会)
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] TBLマウスの小脳性運動失調はユビキチンE3リガーゼのミスセンス変異に起因する2008
- Author(s)
  真下知士, 他3人
- Organizer
  第55回日本実験動物学会総会
- Place of Presentation
  仙台
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] Gene-targeted rat models of human diseases developed by ENU mutagenesis.2008
- Author(s)
  Mashimo T, et al., 他6人
- Organizer
  The 3rd AFLAS Congress
- Place of Presentation
  Beijing, China
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] Gene-targeted rat models of human diseases developed by ENU mutagenesis.2008
- Author(s)
  真下知士, ら
- Organizer
  The 3rd AFLAS Congress & the 8th CALAS Annual Meeting.
- Place of Presentation
  Beijing, China
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-20240042
[Presentation] ENUミュータジェネシスにより作製したSCN1A遺伝子変異ラットの特徴について2007
- Author(s)
  真下知士、他
- Organizer
  第3回日本てんかん学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] NBRPラットリソースのデータベース2007
- Author(s)
  真下知士
- Organizer
  第33回筑波実験動物研究会
- Place of Presentation
  筑波
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスによる標的遺伝子改変ラットの作出方法2007
- Author(s)
  真下知士
- Organizer
  第64回理研BRCセミナー
- Place of Presentation
  筑波
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] Gene-targeted rat models of human epilepsy efficiently developed by ENU mutagenesis.2007
- Author(s)
  Mashimo T, et. al.
- Organizer
  The 2007 meeting on Rat Genomics & Models
- Place of Presentation
  New York, USA
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスにより作製したSCN1A遺伝子変異ラットの特徴について2007
- Author(s)
  真下知士, ら
- Organizer
  第3回日本てんかん学会近畿地方会
- Place of Presentation
  京都
- Year and Date
  2007-11-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] A missense mutation in the mouse gene encoding Hercl ubiquitin ligase results in Purkinje cells degeneration with severe ataxia.2007
- Author(s)
  Mashimo T, et. al.
- Organizer
  21st International Mammalian Genome Conference
- Place of Presentation
  Kyoto
- Year and Date
  2007-10-30
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスにより作製されたScnla遺伝子変異ラット2007
- Author(s)
  真下知士, ら
- Organizer
  Neuro2007
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] ENUミュータジェネシスによるSCNIA遺伝子変異ラットの開発2007
- Author(s)
  真下知士、他
- Organizer
  第54回日本実験動物学会総会
- Place of Presentation
  東京
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] ENUミュータジェネシスによるSCN1A遺伝子変異ラットの開発2007
- Author(s)
  真下知士, ら
- Organizer
  第54回日本実験動物学会総会
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] Gene-targeted rat models of human epilepsy efficiently developed by ENU mutagenesis2007
- Author(s)
  Mashimo, T., et. al.
- Organizer
  The 2007 meeting on Rat Genomics & Models
- Place of Presentation
  Cold Spring Harbor, New York, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] Gene-targeted rat models of human epilepsy efficiently developed by ENU mutagenesis.2007
- Author(s)
  Mashimo T, et. al.
- Organizer
  The 2007 meeting on Rat Genomics & Models
- Place of Presentation
  Cold Spring Harbor
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] Efficient generation of rat models of human diseases by gene driven ENU mutaenesis2007
- Author(s)
  Mashimo T
- Organizer
  The Jackson Laboratory Seminar,
- Place of Presentation
  Maine, USA
- Year and Date
  2007-12-10
- Data Source
  KAKENHI-PROJECT-19650106
[Presentation] MuT-POWER: ENUミュータジェネシスにおける新規DNAスクリーニング法2006
- Author(s)
  真下知士, ら
- Organizer
  第53回日本実験動物学会総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] ENUミュータジェネシスによる新規ラットリソース資源2006
- Author(s)
  真下知士, ら
- Organizer
  第23回日本疾患モデル学会
- Place of Presentation
  渋川
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] MuT-POWER : a high-throughput DNA screening method for detecting ENU-induced mutations2006
- Author(s)
  Mashimo, T., et. al.
- Organizer
  20th International Mouse Genome Conference
- Place of Presentation
  South Carolina
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] ENUミュータジェネシスによるラットリソース:新規てんかんモデルの開発2006
- Author(s)
  真下知士, ら
- Organizer
  第92回関西実験動物研究会
- Place of Presentation
  京都
- Year and Date
  2006-12-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] MuT-POWER: a high-throughput DNA screening method for detecting ENU-induced mutations2006
- Author(s)
  Mashimo T, et. al.
- Organizer
  20th International Mouse Genome Conference,
- Place of Presentation
  South Carolina
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16200029
[Presentation] ゲノム編集技術の最前線：CRISPR/Casシステムを用いた肥満モデル動物の開発
- Author(s)
  真下知士
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎シーガイアコンベンションセンター
- Year and Date
  2014-10-24 – 2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] 遺伝子改変ラットの開発研究
- Author(s)
  真下知士
- Organizer
  第6回ラットリソースリサーチ研究会・第1回実験動物科学シンポジウム
- Place of Presentation
  京都大学（京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] TALENを用いた遺伝子改変ラットの効率的な作製方法
- Author(s)
  真下知士（他3人、1番目）
- Organizer
  第２回ゲノム編集研究会
- Place of Presentation
  岡崎コンファレンスセンター（岡崎市）
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] TALENを用いた遺伝子改変ラットの効率的な作製方法
- Author(s)
  真下知士、金子武人、国広弥生、芹川忠夫
- Organizer
  第2回ゲノム編集研究会
- Place of Presentation
  岡崎コンファレンスセンター（愛知県）
- Data Source
  KAKENHI-PROJECT-24700427
[Presentation] SCID rats as an animal model for preclinical xenotransplantation
- Author(s)
  真下知士
- Organizer
  京都大学医学研究科大学院教育コース腫瘍学エリアミーティング
- Place of Presentation
  京都大学（京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] DNA-PKのラット特異的な機能制御について
- Author(s)
  真下知士（他3人、1番目）
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Generation of severe combined immune deficient (SCID) rats.
- Author(s)
  真下知士（他4人、1番目）
- Organizer
  The 4th EMBO Meeting
- Place of Presentation
  Nice Acropolis（フランス）
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 新たに作製した免疫不全症モデルの創薬への応用（ZFN・TALEN遺伝子改変技術/SCIDラット）
- Author(s)
  真下知士・芹川忠夫
- Organizer
  ＤＳＡＮＪ疾患別商談会（免疫、炎症、アレルギー性疾患領域）
- Place of Presentation
  大阪産業創造館（大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Efficient gene targeting by TAL effector nucleases coinjected with exonucleases in zygotes.
- Author(s)
  真下知士（他7人、1番目）
- Organizer
  Techniques and Procedures for Rat Gene Targeting, Reproduction, and Cryopreservation
- Place of Presentation
  Moler Centre（イギリス）
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Efficient generation of knockin rats by CRISPR/Cas9 with single-stranded oligonucleotides
- Author(s)
  真下知士
- Organizer
  第5回新潟大学脳研究所共同研究拠点国際シンポジウム（BRI International Symposium 2015）
- Place of Presentation
  新潟大学脳研究所
- Year and Date
  2015-03-05 – 2015-03-06
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] マウス・ラット表現型から疾患を推論するソフトウェアの開発
- Author(s)
  桝屋啓志、古崎晃司、高田豊行、真下知士、若菜茂晴、大江和彦、溝口理一郎
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Data Source
  KAKENHI-PROJECT-23300161
[Presentation] TALEN技術について
- Author(s)
  真下知士
- Organizer
  平成24年度和光純薬工業代理店夏期講習会
- Place of Presentation
  和光純薬工業株式会社（大阪市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] ゲノム編集技術が実験動物科学を変える！」、、
- Author(s)
  真下知士
- Organizer
  日本実験動物科学技術さっぽろ2014
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2014-05-15 – 2014-05-17
- Invited
- Data Source
  KAKENHI-PROJECT-26290033
[Presentation] ラットを中心とした遺伝子改変動物研究の現状
- Author(s)
  真下知士、芹川忠夫
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場（福岡市）
- Invited
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] 人工ヌクレアーゼTALENによるノックアウトラットの作製
- Author(s)
  真下知士（他5人、1番目）
- Organizer
  第59回日本実験動物科学・技術九州2012
- Place of Presentation
  別府国際コンベンションセンター（別府市）
- Data Source
  KAKENHI-PROJECT-21680037
[Presentation] Generation of GFP-knockin Rats at the Rosa26 Loci by the CRISPR/Cas9 System
- Author(s)
  Mashimo T, Yoshimi Y, Kaneko T, Voigt B
- Organizer
  Rat Genomics & Models 2014
- Place of Presentation
  Hinxton, UK
- Year and Date
  2014-12-01 – 2014-12-04
- Data Source
  KAKENHI-PROJECT-26290033
[]

1. OGI Tomoo (80508317)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. INOUE Jun-ichiro (70176428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAKAMURA Takuro (00180373)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. TAKADA Masahiko (00236233)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YAMADA Yasuhiro (70313872)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. TAKAHASHI Satoru (50271896)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. IKAWA Masahito (20304066)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. ARAKI Kimi (90211705)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. YAO Ryoji (80291095)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. KOBAYASHI Kazuto (90211903)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. TOYOKUNI Shinya (90252460)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
12. FUTAKUCHI Mitsuru (60275120)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. UENO Masaki (30322267)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. MIYAZAKI Tatsuhiko (80239384)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. KANDA Hiroaki (90260067)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
16. IKEDA Kazutaka (60281656)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. BITO Haruhiko (00291964)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
18. MIYAKAWA Tsuyoshi (10301780)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
19. TAKAO Keizo (80420397)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
20. MUSHIAKE Hajime (80219849)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
21. SEIMIYA Hiroyuki (50280623)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
22. DAN Shingo (70332202)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
23. KAWADA Manabu (20300808)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
24. TAHARA Hidetoshi (00271065)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
25. MATSUURA Masaaki (40173794)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
26. 光武範吏 (50404215)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
27. 吉見一人 (50709813)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
28. SERIKAWA Tadao (30025655)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
29. OMORI Iori (20403488)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
30. MAUSUYA Hiroshi (40321814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
31. KURAMOTO Takashi (20311409)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
32. OUCHIDA Mamoru (80213635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
33. MIZOGUCHI Riichiro (20116106)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
34. KOZAKI Kouji (00362624)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
35. TAKADA Toyoyuki (20356257)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
36. KANEKO Takehito (30332878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 38 results
37. Imaoka Tatsuhiko (40356134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
38. IMAI Kohzoh (60117603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
39. TAKEKAWA Mutsuhiro (30322332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
40. YOSHIDA Nobuaki (10250341)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
41. SAKIMURA Kenji (40162325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
42. WANIBUCHI Hideki (90220970)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
43. IMAIDA Katsumi (90160043)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
44. OSADA Hiroyuki (80160836)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
45. IMOTO Masaya (60213253)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
46. TASHIRO Etsu (00365446)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
47. YOSHIDA Minoru (80191617)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
48. USHIJIMA Masaru (60328565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
49. 阿部学 (10334674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
50. 井手聡一郎 (30389118)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
51. 小山内実 (90286419)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
52. OHNO Yukihiro (00432534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
53. WAKANA Shigeharu (90192434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
54. FUKUDA Noboru (40267050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
55. UENO Takahiro (40386008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
56. NISHIYAMA Akira (10325334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
57. YAMAMOTO Takashi (90244102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
58. NABIKA TORU (50180534)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
59. ARAI Masami (20232027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
60. DAINO Kazuhiro (90543299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
61. MORIOKA Takamitsu (70253961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
62. SHINOHARA Takashi (30322770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
63. OGAWA MASAAKI (00716186)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
64. HATTORI Masakazu (40211479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
65. Inohara Hidenori (00273657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
66. ONAMI Shuichi (50348843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
67. Harashima Shinichi (80444793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
68. HOSODA Kiminori (40271598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
69. TOMITA Tsutomu (50402897)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
70. Kurosaka Hiroshi (20509369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
71. NISHIKAWA Yuji (90208166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
72. 中島玲子 (50372595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
73. 夘野善弘 (80252683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
74. 家森幸男 (80025600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
75. 福島祐二 (90583146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
76. 森下竜一 (40291439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
77. 大野ゆう子 (60183026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
78. 藤堂剛 (90163948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
79. 武石一樹 (50733713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
80. 鈴木啓一郎 (70433654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
81. 中田慎一郎 (70548528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
82. 犬伏俊博 (30550941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
83. 中谷明弘 (60301149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
84. 山城隆 (70294428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
85. 沖真弥 (90452713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
86. 宮井尊史 (40599007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
87. 高地雄太 (60415156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
88. 山崎聡 (50625580)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
89. 小林憲太 (70315662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
90. 井上謙一 (90455395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
91. 高松学 (00750366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
92. 新田淳美 (20275093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
93. 馬島哲夫 (30311228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
94. 堂前直 (00321787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
95. 松本健 (60222311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
96. 掛谷秀昭 (00270596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
97. 澤崎達也 (50314969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
98. 石田紗恵子 (50777927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
99. 竹下浩平 (80346808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
100. ISHINO Seiya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
101. Cho Hironori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
102. Kishikawa Toshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
103. Yamamoto Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
104. Tokita Yuko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
105. OSHIMA Masanobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
106. OZAWA Manabu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
107. SASAOKA Toshikuni

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
108. TAKEDA Naoki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
109. NODA Taichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
110. TAKANO Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
111. SUGIYAMA Fumihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
112. MIZUNO Seiya

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
113. MATSUZAKI Masanori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
114. KOSHIMIZU Hisatsugu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
115. HAGIHARA Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
116. NAKAO Akito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
117. HATTORI Satoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
118. SHOJI Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
119. FUJII Kazuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
120. FUJII Hajime

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
121. TANAKA Tetsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
122. KATAYAMA Norihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
123. MORIYA Yuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
124. NISHIZONO Hirofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
125. NISHIZAWA Daisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
126. YAMORI Takao

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
127. TOMIDA Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
128. MUROI Makoto

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
129. TANIGUCHI Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
130. KATO Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
131. AKATSUKA Shinya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
132. YOSHIMOTO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
133. YASODA Akihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
134. YOKOTA Takahumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
135. TAGUCHI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
136. KUSAKABE Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
137. ABE Koichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
138. RA Chisei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
139. 安村美里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
140. 大屋愛実

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
141. 関根章博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
142. 浅沼幹人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
143. 宮崎育子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
144. 柳川右千夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
145. 田中智洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
146. 丸山一男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
147. 丸山淳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
148. 佐藤守俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
149. 佐久間哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
150. 梅田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
151. 清水佐紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
152. 金倉譲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
153. 土居由貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
154. 上田智朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
155. 新開泰宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
156. 小澤孝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
157. 増田章男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
158. 杉山悠真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
159. 池田昭夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
160. 藤原和之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
161. 安田浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
162. 赤石樹泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mashimo Tomoji 真下 知士

MASHIMO Tomoji 真下 知士

Research Projects

Research Products

Co-Researchers

Development of novel gene editing methods based on the elucidation of the Type I CRISPR genome editing mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo mass culture system of human iPS cell-derived hepatocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New development of genome editing technologies and disease modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Principal Investigator(Support)

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Mashimo Tomoji 真下知士

MASHIMO Tomoji 真下知士