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SASATSUKI Takehiko  笹月 健彦

ORCIDConnect your ORCID iD *help
… Alternative Names

笹月 建彦  ササヅキ タケヒコ

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Researcher Number 50014121
External Links
Affiliation (based on the past Project Information) *help 2016 – 2020: 九州大学, 高等研究院, 特別主幹教授
2010 – 2014: Kyushu University, 生体防御医学研究所, その他
2010 – 2014: 九州大学, 生体防御医学研究所, 特別主幹教授
2012: 九州大学, 高等研究院, 特別主幹教授
2009: 東京大学, 国立国際医療センター, 総長 … More
2009: Research Institute, International Medical Center of Japan, 特任研究員
2003 – 2009: RESEARCH INSTITUTE, INTERNATIONAL MEDICAL CENTER OF JAPAN, DIRECTOR-GENERAL, 所長
2007: 東京大学, 国立国際医療センター, 総長
2001 – 2006: 国立国際医療センター, 研究所長
2004: 国立国際医療センター研究所, 総長
2001 – 2003: International Medical Center of Japan, Research Institute, Director, 研究所, 所長
2001 – 2003: 国立国際医療センター, 研究所, 所長(研究職)
2001 – 2002: 国立国際医療センター研究所, 所長
2000 – 2001: 九州大学, 医学研究院, 教授
1986 – 2001: Kyushu University・ Professor, 生体防御医学研究所, 教授
2000: 九州大学, 生体防御研究所, 教授
1999: 九州大学, 生態防御医学研究所, 教授
1994 – 1997: 九州大学, 生医研, 教授
1996: 九州大学, 生体防御医学研究所, 助手
1995: 九州大学, 生体防衛医学研究所, 教授
1992: Medical Institute of Bioregulation, Kyusyu University, 生体防御研究所, 教授
1989 – 1991: 九州大学, 生医研, 教授
1990: Kyushu University Genetics Medical Institute of Bioregulation, 生体防御研究所, 教授
1990: 九州大学生体防御医学研究所, 教授
1988: Kyushu University, Medical Institute of Biorequlation, 生体防衛医学研究所, 教授
1986: Kyushu University . Professor, 生体防医研, 教授
1986: 九州大学, 体防御医学研究所, 教授
1985: 九州大学, 生体防医研, 教授 Less
Review Section/Research Field
Principal Investigator
Immunology / Biological Sciences / Biological Sciences / Human genetics / 内科学一般
Except Principal Investigator
Immunology / Biological Sciences / 内科学一般 / Biological Sciences / Otorhinolaryngology … More / Urology / Pediatrics / Human genetics / Orthopaedic surgery / Digestive surgery / Metabolomics / Urology / Laboratory medicine / 遺伝 Less
Keywords
Principal Investigator
HLA / トランスジェニックマウス / 免疫制御 / 免疫応答 / 自己免疫疾患 / DNAタイピング / MHC / がん遺伝子 / 免疫寛容 / 家族性大腸ポリポーシス … More / TCR / 環境要因 / 抗原ペプチド / 抗原提示 / 免疫遺伝 / 遺伝要因 / DNA typing / トランスフェクタント / 遺伝的多型性 / 遺伝子 / サプレッサーT細胞 / スギ花粉症 / 疾患感受性 / SNP / ペプチド / T細胞レパトア / 珪肺症 / 大腸がん / ペプチド複合体 / HLA-DM / immune regulation / HLA-B27 / HLA-A2 / Immune response / 免疫抑制 / T細胞レパトワ / サイトカイン / 多重遺伝子族 / RFLP解析 / 連鎖検定 / HLA-DQ / 単クローン抗体 / 免疫応答遺伝子 / 免疫抑制遺伝子 / グレーブス病 / ゲノム / 疾病感受性 / 立体構造 / HLA / 相関解析 / マイクロサテライトマーカー / 罹患同胞対法 / 連鎖解析 / 胃がん / c-myc遺伝子 / 第5染色体 / HLAクラスII遺伝子 / 遺伝子増幅 / 免疫遺伝学 / p53遺伝子 / がん抑制遺伝子 / Transfectant / Polymerase chain reaction / Antigen presentation / Disease susceptibility gene / Immune suppression / Immunogenetics / 前駆体T細胞頻度 / 限界希釈分析法 / L細胞 / リンパ球混合培養反応 / HLAーDQ分子 / HLAーDR分子 / T細胞増殖反応 / 溶連菌抗原 / ポリメラ-ゼ鎖反応 / 形質転換細胞 / ポリメラ-ゼ連鎖反応 / 疾病感受性遺伝子 / cryptomeria pollen / schistosoma japonicum / streptococcal cell wall / immune response genes / immune suppression genes / らい菌抗原 / スギ花粉抗原 / 日本住血吸虫抗原 / 溶連菌細胞壁抗原 / HLA-クラス【II】分子 / microsatellite / association / linkage / polymorphism / genome / gastric cancer / LOD値 / 全ゲノムスクリーニング / 多因子疾患 / SNPs / 全ゲノムスキャン / 相関 / 連鎖 / 罹患同胞対 / マイクロサテライト / 遺伝子多型 / homeostasis / chromosome / immune system / multistep carcinogenesis / environmental factors / gene / oncogenesis / cancer / 細胞 / 環境 / 染色体 / 発生工学 / 免疫 / 家系 / 多段階発がん / がん / affinity / off rate / leucine zipper / peptide complex / soluble MHC / soluble TCR / Leucin Zipper / 高親和性 / PI-PLC / GPIアンカー / 親和性 / 解離定数 / ロイシンジッパー / ペプチド複合体(3) / 可溶性MHC / 可溶性TCR / kinetic stability / T cell repertoire selection / peptide / 胸腺T細胞の選択 / TAP / 胸腺内T細胞の選択 / HLA-DO / プロセシング / T細胞受容体 / 主要組織適合抗原 / ノックアウトマウス / 単-MHC / 安定性 / T細胞レパートリーの選択 / K-ras gene / homologous recombination / Colon cancer cell lines / 相同組み換え / P53 / K-ras / 血管内皮増殖因子 / 大腸癌細胞株 / K-ras遺伝子 / 遺伝子相同組み換え / 大腸菌細胞株 / proteosome / prosessing / antigenic peptide / プロテオゾーム / アポトーシス / γδ型T細胞 / プロテアゾーム / プロセッシング / gene knockout mouse / transgenic mouse / international symposium / information exchanges / providing information / group of generalization / immune tolerance / ジーンノックアウトマウス / 国際シンポジウム / 情報交換 / 情報提供 / 総括班 / cedar pollinosis / Hepatitis B vaccine / T細胞エピトープ / HLA結合ペプチド / HLA-A遺伝子 / HBs抗原 / 溶連菌M蛋白 / トランスジェニックスマウス / HLA-B52 / HLA-B51 / B型肝炎ワクチン / Genetic polymorphism / Transgenic mouse / Antigenic peptide / HLA-DP9 / MHC結合性ペプチド / T cell repertoire / Autoimmune disease / Transgenic mice / Disease susceptibility / Polymorphism / 細胞傷害活性 / CD8^+T細胞 / 対立遺伝子 / 抗原ぺプチド / スーパー抗原 / 分子進化 / 細胞免疫学 / 蛋白化学 / 分子生物学 / 臓器移殖 / 蛋白質 / 多型 / 国際HLAワークショップ / 臓器移植 / プロモーター / 核蛋白 / サザンハイブリダイゼーション法 / T細胞レセプター遺伝子 / 免疫グロブリン / 補体遺伝子 / 高ガンマグロブリン血症 / 対立遺伝子欠損 / 多重遺伝子属 / 遺伝子重複 / 遺伝子変換 / 先天性副腎過形成 / 分子進化, 遺伝病 / 補体第4成分 / がん関連抗原 / ヘテロザイゴシティの消失 / cーfos / cーmyc / 大腸癌 / HLA抗原 / 遺伝子発現 / 日本住血吸虫症 / HLA-クラス【II】抗原 / HLA-抗原系 / 硅肺症 / 二次元ゲル電気泳動 / TPA / C-myc発がんプロモーター / C-Ha-ras / HLA-DQ抗原 / HLA-DR抗原 / サプレッサー因子 / IgE免疫応答 / 4B4 / 免疫抑制因子 / アレルギー / 花粉症 / HLA-DR53 / HLA-DP5 / DP5 / 自己免疫性甲状腺炎 / VAV3 / ゲノム解析 / エピスターシス / HLA立体構造 / 橋本病 / HLA-DR53 / HLA-DP5 / 自己免疫病 / HLA立体構造 / 疾病 / データベース / 進化 / 移植 / 疾患抵抗性 / ゲノム多様性 / SLE / ZEAT / FCRL3 / リンパ球 / 転写制御因子 / 遺伝子改変マウス / ZFAT / 疾患感受性遺伝子 / 自己免疫性甲状腺疾患(AITD) / 発がん / DNA多型マーカー / 全ゲノムスキャニング / 慢性関節リュウマチ / HLA-DR / プロテアソーム / NK1.1 / CD40 / MHCの進化 / T細胞分化 / T細胞活性化 / 抗原提示細胞 / T細胞 / Toll-like receptor / プロテマソーム / HLAゲノム解析 / γδT細胞 / 樹状細胞 / T細胞抗原受容体 / P53遺伝子 / APC遺伝子 / MDC遺伝子 / 乳がん / 高発がん家系 / 免疫病 / ras遺伝子 / 遺伝子ターゲッティング / レパトア欠失 / ジ-ンタ-ゲッティング / Kーras遺伝子 / 癌抑制遺伝子 / 癌遺伝子 / FPC(家族性大腸腺腫症) / ヒト・マウス融合細胞 / 大腸腺腫 / Dcc遺伝子 / FPC主遺伝子 / 家族性大腸ポリポ-シス / M蛋白 / 抗原 / T細胞レセプタ- / プロモ-タ-領域 / 多型性 / HLAクラスIII領域 / 合成オリゴヌクレオチド / PCR法 / 高感受性集団 / 国際主要組織適合性ワ-クショップ / 臓器移植学 / 臨床遺伝学 / 進化遺伝学 / 集団遺伝学 / ヒト主要組織適合抗原複合体(HLA) / 微少核融合法 / 腺腫 / 高発がん性遺伝性疾患 … More
Except Principal Investigator
HLA / 自己免疫疾患 / MHC / サイトカイン / シグナル伝達 / HLAタイピング / 免疫応答 / 転写因子 / ゲノム / マイクロサテライトマーカー / 家族性大腸ポリポージス / TCR / アレルギー / HLA-DR / T細胞 / autoimmune disease / signal transduction / cytokine / トランスジェニックマウス / IL-6 / IL-5 / 疾患感受性遺伝子 / 免疫病 / ペプチド / がん抑制遺伝子 / 自己免疫 / 対立遺伝子のヘテロ接合型消失 / DNA修復 / 色素性乾皮症 / IgE / SNP / SNPs / EST / ペプチド複合体 / analogue peptide / molecular mimicry / ミトコンドリア抗原 / T細胞エピトープ / 自己免疫性疾患 / 抗ミトコンドリア抗体 / アナログペプチド / 分子相同性 / 原発性胆汁性肝硬変 / Lyn / Src / SSl-1 / STAT / FasL / 免疫制御 / 免疫異常 / B細胞 / 免疫寛容 / T cell / 増殖因子 / 正の選択 / 抗原ペプチド / B70 / Biosensor / NMR / transcription factor / 主要組織適合抗原 / HLA-Bw52 / FK506 / T cell receptor / Aortography / TNF / 遺伝子発現 / 染色体分析 / ポリープ発生関連cDNAクローン / 連鎖分析 / 連鎖解析 / 罹患同胞対法 / Graves病 / 橋本病 / 甲状腺 / 情報伝達 / レパートリー形成 / 腫瘍免疫 / アポトーシス / がん遺伝子 / 細胞分化 / 分化 / 遺伝子 / がん / ミスマッチ修復酵素 / マイクロサテライト不安定性 / T細胞レパートリー / 移植抗原 / 遺伝病 / 染色体異常 / 蛋白質 / 立体構造 / アレルギー・ぜんそく / タンパク質 / 免疫学 / German-Japanese collaborative program in cancer research / French-Japanese collaborative programe in cancer research / Growth Factors / Cytokines / Tumor Suppressor Genes / Oncogenes / Human Gene Mapping / International Exchange Program / 発がん / ヒトがん遺伝子 / ヒトレトロウイルス / disease susceptibility / HLA class II antigen / クラス【II】抗原 / 第3回アジア・オセアニア組織適合性ワークショップ・コンフェレンス / 制限酵素断片長多型解析 / 遺伝子クローニング / クラス11抗原 / トランスジュニックマウス / トランスフェクション / 疾患感受性 / HLAクラスII抗原 / Allergy / Cryptomeria pollinosis / Suppressor T cells / Immune response gene / Immune suppression gene / 4B4 / 活性化T細胞 / サプレッサーT細胞スギ花粉症 / 免疫応答遺伝子 / 免疫抑制遺伝子 / genome / polymorphism / prostate cancer / 遺伝子多型 / 前立腺癌 / Linkage analysis / Cytotoxicity of Tlymphocytes / NK activity / MUNC13-4 gen / Performn gene / Familial hemophagocytic lymphohistiocytosis / マウスモデル / 原発性血球貪食症候群 / 細胞障害活性 / 遺伝子導入 / linkage analysis / リンパ球細胞障害活性 / NK活性 / MUNC13-4遺伝子 / perforin遺伝子 / 家族性血球貪食症候群 / antisense RNA / association / linkage / affected sib-pairs / microsatellite marker / susceptibility gene / AITD / ZFAT / アンチセンスRNA / 相関解析 / 罹患同胞対 / 自己免疫性甲状腺疾患 / Diabetes / high blood pressure / circulatory organ / A genome / Allergic asthma / DNAチップ / リュウマチ / 多因子疾患 / 喘息 / 高血圧 / 糖尿病 / 循環器・高血圧 / アレルギー喘息 / Outreach / Resources / Genome Sequencing / 医科学倫理問題 / マイクロサテライト / 多型タイピング / ESTシーケンシング / ヒト多型タイピング / 産学連携 / アウトリーチ活動 / 発生進化 / 霊長類ゲノム / 比較ゲノム / 脊椎動物進化 / 遺伝子機能 / 計算機モデル化 / モデル生物 / 社会との接点 / リソース / ゲノムシーケンシング / autoimmunity / positive and negative selection / antigenic peptides / CDR3 / 単一MHC / 胸腺内T細胞分化 / 正と負の選択 / T細胞受容体 / mitochondrial antigen / PDC-E2 / antigen-specific immunotherapy / immune-regulation / primary biliary cirrhosis / 原発性胆汁性肝研変 / 抗原特異的治療法 / anti-mitochondria antibody / autoantigen / auto-reactive T cell / autoantibody / autoimmune / Primary Biliary Cirrhosis / MHC複合体 / 自己抗原 / 自己反応性T細胞 / 自己抗体 / inflammation / cell differentiation / co-receptor / antigen receptor / immune response / ノックアウトマウス / 炎症疾患 / 補助受容体 / 抗原受容体 / Molecular Target Therapy / Gene Manipulated Animals / Cancer Genome / Support for Young Investigators / International Scientific Exchange / Screening / Research Materials / Cancer / 若手支授 / 研究資材 / 医療・福祉 / 癌 / 分子標的治療 / 遺伝子操作動物 / がんゲノム / 若手支援 / 国際学術研究交流 / スクリーニング / 研究資料 / TGF-beta / CD40-CD40L / TCR-peptides / CD40 / Smad / TGF-β / xenogeneic response / allogeneic response / transgenic mouse / 異種MLR / 自己抗原ペプチド / HLA-DQ6 / 移植 / ゼノ反応性 / アロ反応性 / Signal transduction / Immunological disorders / Inflammation / Tyrosine kinase / Immunodiversity / Antigen receptor / Repertoire selection / 免疫不全 / 自己認識 / 免疫病の分子機構 / 自己免疫病 / 抗原レセプター / MHCと抗原ペプチド / 免疫職別の多様性 / 免疫職別の多型性 / 新しい診断法 / 免疫病とその修復 / リンパ球の機能分化 / 免疫識別の多様性 / 免疫識別の多型性 / CD95L / HSI / CD80, CD86 / CD40, CD40L / Transcriptional factor / Crystallin gene / Polycomb genes / Transgenics / B cell / Immunological tolerance / 有機リン系農薬センサー / 水晶体特異的遺伝子発現 / ポリコ-ム遺伝子 / 発生工学 / antigen / peptide / HLA-DP antigen / allergy / HLA-DP / GvH病 / 抗原 / スギ花粉症 / positive selection / stromal cell / progenitor / hematopoietic stem cell / differentiation / thymus / 正・負の選択 / 胸腺ストローマ細胞 / 骨髄 / 生長因子 / 決定 / ストローマ細胞 / 前駆細胞 / 造血幹細胞 / 胸腺 / antigenic peptide / MHC molecule / adhesion molecule / CD5^+B cells / apoptosis / self-tolerance / MHC分子 / 接着分子 / CD5^+B細胞 / アポプトーシス / 自己トレランス / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / major histocompatibility antigen / autoimmune diseases / gene expression / receptor / lymphocytes / レセプター / リンパ球 / Autoimmune disease / Superantigen / Antigen processing / RAG 1 / Cytokine receptor / ス-パ-抗原 / 抗体のプロセッシング / RAG1 / サイトカインレセプタ- / Hypertension / Aortic regurgitation / Takayasu arteritis / 磁気共鳴画像 / 腎性高血圧症 / 高血圧症 / 大動脈弁閉鎖不全 / 大動脈造影 / 高安動脈炎 / Cell fusion / HLA transgenic mouse / Allo-specificity / Hybridoma / Monoclonal antibody / HLA-DQトランスジェニックマウス / ヒト主要組織適合抗原系(HLA) / HLAアロ抗原 / 細胞融合 / ハイブリド-マ / HLAトランスジェニックマウス / アロ抗原性 / 単クロ-ン抗体 / neutrophils / G-CSF / passive arthritis / anti-type II collagen antibody / collagen-induced arthritis / rheumatoid arthritis / 血清移入 / 好中球 / 顆粒球コロニ-形成刺激因子 / 受け身移入関節炎 / 抗II型コラ-ゲン抗体 / コラ-ゲン関節炎 / 慢性関節リウマチ / Transcription factor / Expression / Promoter region / Polymorphisms / 核蛋白 / 転写調節 / HLAクラスII遺伝子 / DNAタイピング / IFN / 発現調節 / 発現制御 / プロモ-タ- / 遺伝的多型性 / Acute phase reaction / NF-IL-6 / Interleukin / Recombinase / IgM receptor / Major histocompatibility complex (MHC) / The US-Japan Immunology Symposium / 急性期反応 / MF-IL-6 / インタ-ロイキン / リコンビナ-ゼ / IgMレセプタ- / 主要組織適合抗原(MHC) / Tリンパ球レセプタ- / 日米免疫シンポジウム / Takayasu arteritis in Korea / 血管造影 / 補体蛋白多型性 / HLA typing / 韓国人の高安動脈炎 / 日本人の高安動脈炎 / CTF / インターフェロン / 組織特異性 / 組みかえDNA / インターロイキン / トランスゲニックマウス / 肺癌 / 日本住血吸虫性肝硬変 / 硅肺症 / 遺伝標識 / 遺伝因子 / 環境因子 / 高感受性集団 / 環境疫学 / 環境毒性 / 人体影響 / cDNAクローン / c-sis / DNA多型マーカー / 多臓器癌 / 膵癌 / IPMT / 遺伝子データベース / 全ゲノムスキャン / 生活習慣病 / テーラーメード医療 / 罹患同胞対解析 / 2型糖尿病 / ゲノムインフォーマティックス / 遺伝医学 / 生命倫理 / ゲノムインフォーマティック / 病原微生物 / 有用微生物 / 多型解析 / 分子遺伝学 / 社会医学 / 微生物 / 臨床 / 産業微生物ゲノム / 微生物ゲノム / メディカルインフォマティクス / ヒトゲノム配列再解析 / ゲノムワイド関連解析 / 疾患関連遺伝子 / 発癌 / 前立腺がん / インフォームドコンセント / 胎児診断 / 日本遺伝子診療学会 / UNESCO / ガイドライン / 非メンデル遺伝 / 遺伝子診断 / データベース / 遺伝子情報 / 機能分化 / 免疫識別 / 細胞傷害性T細胞 / ファンコニ貧血 / 肺がん / 乳がん / 大腸がん / 高発がん家系 / 癌遺伝子 / Ki-ras / HLA-クラスI / アボトーシス / 細胞生物学 / がん細胞 / ヒトがん / がん転移 / 細胞増殖 / 細胞間相互作用 / 転移 / 細胞死 / 増殖 / 継世代変異 / がん多発家系 / cohort / project / support / steering / cancer research / 成果とりまとめ / 文部省がん研究 / 起源と進化 / MHC拘束 / 非古典的MHC / 下等脊椎動物MHC / クローニング / 染色体地図 / ファンコニ-貧血症 / 突然変異 / 遺伝子地図 / 皮膚がん / 紫外線 / マイクロ波固定癌組織のインサイチュウハイブリダイゼ-ショ / 大腸関連癌遺伝子のcDNAクロ-ニング / 大腸癌培養細胞への単一染色体移入 / 家族性大腸ポリポ-ジス / 遺伝 / ブルーム症候群 / 微小核融合 / Kras遺伝子 / ヘテロ接合型消失 / 5番染色体 Less
  • Research Projects

    (102 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (381 People)
  •  Structural analysis of neo-self

    • Principal Investigator
      YOKOYAMA Shigeyuki
    • Project Period (FY)
      2016 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  Integrated redearch for HLA disease and evolutionPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Genetic and immunological analysis for HLA-DP5 and HLA-DR53 related diseases.Principal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  HLA polymorphism, disease and evolutionArea Organizer

    • Area Organizer
      SASAZUKI Takehiko
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Kyushu University
  •  Immunogenetic Analysis of Autoimmune Thyroid DiseasesPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Research Institute, International Medical Center of Japan
  •  Applied Genomics

    • Principal Investigator
      TSUJI Shoji
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  罹患同胞対を利用した2型糖尿病感受性遺伝子の解明に関する研究

    • Principal Investigator
      中島 直樹
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyushu University
  •  IPMT(膵管内乳頭状粘液性腫瘍)DNA多型解析のための発癌と遺伝要因調査

    • Principal Investigator
      田中 雅夫
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  The identification of prostate cancer susceptible gene by whole genome search and candidate gene approach

    • Principal Investigator
      YOKOMIZO Akira
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyushu University
  •  全ゲノムにわたる相関解析を用いた前立腺がん発症に関する責任遺伝子の検索

    • Principal Investigator
      奥村 幸司
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kyushu University
  •  Analysis of the pathogenesis and identification of candidate genes in familial hemophagocytic lymphohistiocytosis

    • Principal Investigator
      ISHII Eiichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Saga University
  •  がん研究の総合的推進に係る研究

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  橋本病における疾患感受性遺伝子の同定

    • Principal Investigator
      SHIRASAWA Senji
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Genome science towards the understanding of life

    • Principal Investigator
      KOHARA Yuji
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Genetics
  •  Genomic analysis on genetic factors of human diseases and elucidation of their molecular mechanisms

    • Principal Investigator
      SUGANO Sumio
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Genome-wide analyses to identify genes involved in gastric cancerPrincipal Investigator

    • Principal Investigator
      SASAZUKI Tekehiko
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      International Medical Center of Japan
      Kyushu University
  •  GENETIC ANALYSIS ON AUTOIMMUNE THYROID DISEASE

    • Principal Investigator
      SHIRASAWA Senji
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human genetics
    • Research Institution
      RESEARCH INSTITUTE, INTERNATIONAL MEDICAL CENTER OF JAPAN
      Kyushu University
  •  がんの生物学的特性の研究の総括Principal Investigator

    • Principal Investigator
      笹月 健彦, 黒木 登志夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
      Showa University
      The University of Tokyo
  •  免疫識別と応答の多様性の分子機構Principal Investigator

    • Principal Investigator
      西村 泰治, 笹月 健彦
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
      Kyushu University
  •  罹患同胞対法を用いた胃がん関連遺伝子の解明Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  General Promotion of Cancer Research in Japan

    • Principal Investigator
      TSURUO Tahashi
    • Project Period (FY)
      1999 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Mechanisms of oncogenesis and anti-oncogenesisPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1999 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      International Medical Center of Japan
      Kyushu University
  •  Regulatory mechanism of signal transduction in the immune system.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  The analysis of epitope and immunological response of primary biliary cirrhosis

    • Principal Investigator
      HAYASHIDA Kazuhiro, 石橋 大海
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Identification and characterization of T cell epitope in primary biliary cirrhosis

    • Principal Investigator
      NAKAMURA Minoru, 石橋 大海
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular basis for T cell repertoire selection in the thymusPrincipal Investigator

    • Principal Investigator
      FUKUI Yoshinori, 笹月 健彦
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  自己免疫疾患の原因解明・制御を目的としたペプチドライブラリーによる原因抗原の解明Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Kyushu University
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Juntendo University School of Medicine
  •  遺伝子診断推進への基礎的検討-遺伝子情報環境の調査と提言

    • Principal Investigator
      上田 國寛
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kyoto University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  Molecular Basis of Immunological Tolerance and Non-ResponsePrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Juntendo University School of Medicine
  •  Molecular Mechanisms and Intervention of Immunological Diseases.

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Development of soluble TCR and soluble MHC/peptide compelx with high affinity for their ligandsPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  Development of model mouse for human immune system.

    • Principal Investigator
      KAMIKAWAJI Nobuhiro
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  高発がん家系の解析

    • Principal Investigator
      木村 影方
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  HLA結合ペプチドの解析による癌細胞抗原群の同定

    • Principal Investigator
      上川路 信博
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  免疫病の分子機構とその修復

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  Studies on the mechanism of T cell development in the thymus

    • Principal Investigator
      KATSURA Yoshimoto
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      KYOTO UNIVERSITY
  •  Basic research for the development of antigen specific immunosuppressive therapy using HLA.

    • Principal Investigator
      KAMIKAWAJI Nobuhiro
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  高発がん家系の解析

    • Principal Investigator
      木村 彰方
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  HLA結合ペプチドの解析による癌細胞抗原群の同定

    • Principal Investigator
      上川路 信博
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  in vitro manipulation of genes relevant to oncogenesisPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Medical Institute of Bioregulation, Kyushu University
  •  高発がん家系の解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  自己・非自己識別分子MHCの起源と進化

    • Principal Investigator
      高畑 尚之
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      遺伝
    • Research Institution
      The Graduate University for Advanced Studies
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Studies on molecular mechanisms of autoimmune diseases

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Molecular mechanism of immune response requlated by HLAPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular mechanism of immune regulation and immune tolerancePrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Molecular mechanisms of immune regulation.Principal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  FPC発症におけるがん遺伝子とがん抑制遺伝子の役割Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  免疫制御・寛容の分子機構Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  Studies on the regulation of gene expression in lymphoid cells.

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Development of HLA bound peptitides which have supressive activity.Principal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  FPC発症におけるがん遺伝子とガン抑制遺伝子の役割Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  HLAクラスII遺伝子を発現したトランスジェニックマウスの開発Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  ヒト主要組織適合遺伝子複合体の総合的研究

    • Principal Investigator
      片桐 一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Asahikawa Medical College
  •  Comparative Studies on Takayasu Arteritis in Asian Countries

    • Principal Investigator
      NUMANO Fujio
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies on the regulation of gene expression in lymphoid cells.

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Osaka University
  •  Research on the molecular basis for genetic control of immune response in humanPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      KYUSHU UNIVERSITY
  •  HLAおよびT細胞レセプター遺伝子によるヒト免疫応答の遺伝子支配に関する研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kyushu University
  •  FPC発症におけるがん遺伝子とがん抑制遺伝子の役割Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  HAL遺伝子を発現したトランスジェニックマウスの開発Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  ヒト主要組織適合遺伝子複合体の総合的研究

    • Principal Investigator
      片桐 一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Asahikawa Medical College
  •  HLAの分子医学生物学的研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  家族性大腸ポリポージスにおける発癌機構の解析

    • Principal Investigator
      外村 晶
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  高発がん性遺伝病の遺伝子解析

    • Principal Investigator
      TAKEBE Hiraku
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  家族性大腸ポリポーシス由来の大腸がんを用いたがん抑制遺伝子の解明Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  ヒト主要組織適合抗原複合体の総合的研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  HLAクラスIIおよびクラスIII領域遺伝子の分子進化学的研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  高発がん性遺伝病の遺伝子解析

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  高発がん性遺伝病の遺伝子解析

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyoto University
  •  Comparative Studies on Takayasu Arteritis Between Japan and Korea

    • Principal Investigator
      NUMANO Fujio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tokyo Medical and Dental University
  •  Exchange of the informations in the cooperative immunology research between the US-Japan Bords.

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Overseas Scientific Survey.
    • Research Institution
      Institute for Molecular and Cellular Biology, Osaka University
  •  Regulation of ectopic expression of HLA class II genes.

    • Principal Investigator
      KIMURA Akinori
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Medical Institute of Bioregulation, Kyushu University
  •  Studies Using Experimental Animal Models of Rheumatoid Arthritis -Induction Mechanisms into Chronic Status of Joint Inflammation-

    • Principal Investigator
      KOGA Toshitaka, 佛淵 孝夫
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kyushu University
  •  Production of monoclonal antibody specific to HLA by utilizing HLA transgenic mice.

    • Principal Investigator
      NISHIMURA Yasuharu
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Medical Institute of Bioreguration, Kyushu University
  •  家族性大腸ポリポ-ジスにおける発癌機構の解析

    • Principal Investigator
      外村 晶
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  家族性大腸ポリポージスにおける発癌機構の解析

    • Principal Investigator
      外村 晶
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  高発がん性疾患におけるがん化機構Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  珪肺症をモデルとした環境要因に対する高感受性集団の分子生物学的解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  HLAクラスIIおよびクラスIII領域遺伝子の分子進化学的研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  HLAクラスII遺伝子群の発現制御機構

    • Principal Investigator
      木村 彰方
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  Molecular Analyses of the Genetic Control of Immune Response in HumansPrincipal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Medical Institute of Bioregulation, Kyushu University
  •  珪肺症をモデルとした環境要因に対する高感受性集団の分子生物学的解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  家族性大腸腺腫症の遺伝学的解析

    • Principal Investigator
      外村 晶
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  珪肺症とモデルとした環境要因に対する高感受性集団の分子生物学的解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  HLAクラスIIおよびIII領域遺伝子の分子進化学的研究Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  米国西海岸地域における分子免疫生物学の進捗に関する調査研究

    • Principal Investigator
      岸本 忠三
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
  •  家族性大腸腺腫症の遺伝学的解析

    • Principal Investigator
      外村 晶
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokyo Medical and Dental University
  •  高発がん性疾患におけるがん化機構Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  環境要因に対する高感受性集団の応答

    • Principal Investigator
      松本 秀雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Environmental Science
    • Research Institution
      Osaka Medical College
  •  生命科学技術の進展への免疫学の対応

    • Principal Investigator
      多田 富雄
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  高発がん性疾患におけるがん化機構Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  Characters and functions of HLA class II antigens

    • Principal Investigator
      AIZAWA Miki
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Immunology
    • Research Institution
      Hokkaido University
  •  家族性大腸ポリポーシス患者の試料の収集と分子遺伝学的解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  環境要因に対する高感受性集団の応答Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Environmental Science
    • Research Institution
      Kyushu University
  •  人体影響に関する基礎班

    • Principal Investigator
      武部 啓
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Environmental Science
    • Research Institution
      Kyoto University
  •  The analysis of HLA-linked immune suppression genes and their expression.Principal Investigator

    • Principal Investigator
      SASAZUKI Takehiko
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
  •  スギ花粉症をモデルとしたIgE免疫応答の機構の解析Principal Investigator

    • Principal Investigator
      笹月 健彦
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Kyushu University
      Tokyo Medical and Dental University
  •  Analysis of the Immune Suppression Gene in Cryptomeria Pollinosis

    • Principal Investigator
      SAITO Yozo
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Tokyo Medical and Dental University

All 2018 2016 2015 2014 2012 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

  • [Book] ゲノム医科学NOW(自己免疫性甲状腺疾患の疾患感受性遺伝子探査)2006

    • Author(s)
      白澤専二, 笹月健彦
    • Publisher
      クバプロ
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation.2018

    • Author(s)
      Morishima S, Shiina T, Suzuki S, Ogawa S, Sato-Otsubo A, Kashiwase K, Azuma F, Yabe T, Satake M, Kato S, Kodera Y, Sasazuki T, Morishima Y
    • Journal Title

      Blood

      Volume: 131(7) Issue: 7 Pages: 808-817

    • DOI

      10.1182/blood-2017-08-801449

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09884, KAKENHI-PROJECT-17K09934, KAKENHI-PLANNED-16H06500, KAKENHI-PLANNED-16H06502, KAKENHI-PUBLICLY-17H05797, KAKENHI-PROJECT-26221308
  • [Journal Article] Identification of a Hashimoto thyroiditis susceptibility locus via a genome-wide comparison with Graves' disease.2015

    • Author(s)
      Oryoji D, Ueda S, Yamamoto K, Yoshimura Noh J, Okamura K, Noda M, Watanabe N, Yoshihara A, Ito K, Sasazuki T.
    • Journal Title

      J Clin Endocrinol Metab.

      Volume: 100 Issue: 2 Pages: E319-E324

    • DOI

      10.1210/jc.2014-3431

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133003, KAKENHI-PLANNED-22133009
  • [Journal Article] β2-glycoprotein I/ HLA class II complexes are novel autoantigens in antiphospholipid syndrome.2015

    • Author(s)
      Tanimura K, Jin H, Suenaga T, Morikami S, Arase N, Kishida K, Hirayasu K, Kohyama M, Ebina Y, Yasuda S, Horita T, Takasugi K, Ohmura K, Yamamoto K, Katayama I, Sasazuki T, Lanier LL, Atsumi T, Yamada H, Arase H.
    • Journal Title

      Blood

      Volume: 125 Issue: 18 Pages: 2835-2844

    • DOI

      10.1182/blood-2014-08-593624

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PROJECT-23390112, KAKENHI-PLANNED-24115005, KAKENHI-PROJECT-24590584, KAKENHI-PUBLICLY-25133705, KAKENHI-PROJECT-25460565, KAKENHI-PROJECT-25670143, KAKENHI-PROJECT-26462489, KAKENHI-PROJECT-26870334, KAKENHI-PROJECT-15K05577, KAKENHI-PROJECT-15K09514, KAKENHI-PROJECT-15K15418, KAKENHI-PROJECT-15K15419, KAKENHI-PUBLICLY-26117714, KAKENHI-PROJECT-24591436, KAKENHI-PROJECT-25670503
  • [Journal Article] Associations of HLA class I alleles in Japanese patients with Crohn's disease.2015

    • Author(s)
      102)Oryoji D, Hisamatsu T, Tsuchiya K, Umeno J, Ueda S, Yamamoto K, Matsumoto T, Watanabe M, Hibi T, Sasazuki T.
    • Journal Title

      Genes Immun.

      Volume: 16 Issue: 1 Pages: 54-56

    • DOI

      10.1038/gene.2014.61

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22133009, KAKENHI-PROJECT-24590935, KAKENHI-PUBLICLY-25114703, KAKENHI-PUBLICLY-25130704
  • [Journal Article] Biological significance of HLA locus matching in unrelated donor bone marrow transplantation.2015

    • Author(s)
      Morishima Y, Kashiwase K, Matsuo K, Azuma F, Morishima S, Onizuka M, Yabe T, Murata M, Doki N, Eto T, Mori T, Miyamura K, Sao H, Ichinohe T, Saji H, Kato S, Atsuta Y, Kawa K, Kodera Y, Sasazuki T; Japan Marrow Donor Program.
    • Journal Title

      Blood

      Volume: 125 Issue: 7 Pages: 1189-1197

    • DOI

      10.1182/blood-2014-10-604785

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133011, KAKENHI-PROJECT-26293277, KAKENHI-PROJECT-26461455
  • [Journal Article] Structural Basis for the Specific Recognition of the Major Antigenic Peptide from the Japanese Cedar Pollen Allergen Cry j 1 by HLA-DP5.2014

    • Author(s)
      Kusano S, Kukimoto-Niino M, Satta Y, Ohsawa N, Uchikubo-Kamo T, Wakiyama M, Ikeda M, Terada T, Yamamoto K, Nishimura Y, Shirouzu M, Sasazuki T, Yokoyama S.
    • Journal Title

      J Mol Biol.

      Volume: 426 Issue: 17 Pages: 3016-3027

    • DOI

      10.1016/j.jmb.2014.06.020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133004, KAKENHI-PLANNED-22133005, KAKENHI-PLANNED-22133007, KAKENHI-PLANNED-22133009
  • [Journal Article] Identification of independent susceptible and protective HLA alleles in Japanese autoimmune thyroid disease and their epistasis.2014

    • Author(s)
      Ueda S, Oryoji D, Yamamoto K, Noh JY, Okamura K, Noda M, Kashiwase K, Kosuga Y, Sekiya K, Inoue K, Yamada H, Oyamada A, Nishimura Y, Yoshikai Y, Ito K, Sasazuki T.
    • Journal Title

      J Clin Endocrinol Metab.

      Volume: 99 Issue: 2 Pages: E379-E383

    • DOI

      10.1210/jc.2013-2841

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22133001, KAKENHI-PLANNED-22133003, KAKENHI-PLANNED-22133005, KAKENHI-PLANNED-22133009
  • [Journal Article] Ly49Q plays a crucial role in neutrophil polarization and migration by regulating raft trafficking.2010

    • Author(s)
      Sasazuki T(8番目), Toyama-Sorimachi N(10番目:全10名)
    • Journal Title

      Immunity 32

      Pages: 200-213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Gasp, a Grb2 associating protein, is critical for positive selection of thymocytes.2009

    • Author(s)
      Sasazuki T(11番目), Suzuki H(12番目:全12名)
    • Journal Title

      Proc. Natl. Acad. Sci. USA 106

      Pages: 16345-16350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] ZFAT is an antiapoptotic molecule and critical for cell survival in MOLT-4 cells.2009

    • Author(s)
      Sasazuki T(7番目), Shirasawa S(8番目:全8名)
    • Journal Title

      FEBS Lett 583(3)

      Pages: 568-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Spatiotemporal regulation of intracellular trafficking of TLR9 by an inhibitory receptor2009

    • Author(s)
      Sasazuki T(7番目), Toyama-Sorimachi N(10番目:全10名)
    • Journal Title

      Ly49Q. BLOOD 114

      Pages: 1518-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Onecut transcription factor OC2 is a direct target of T-bet in type-1 T-helper cells.2008

    • Author(s)
      Sasazuki T(7番目), Yamamoto K(8番目:全8名)
    • Journal Title

      Genes Immun. 9(4)

      Pages: 302-308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] ZFAT expression in B and T lymphocytes and identification of ZFAT-regulated genes.2008

    • Author(s)
      Sasazuki T(10番目), Shirasawa S(11番目:全11名)
    • Journal Title

      Genomics 91(5)

      Pages: 451-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2.2007

    • Author(s)
      Sasazuki T(12番目:全13名)
    • Journal Title

      Nat Immunol. 8(10)

      Pages: 1067-75

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Analysis of KRAP expression and localization, and genes regulated by KRAP in a human colon cancer cell line2007

    • Author(s)
      Fujimoto, T., Koyanagi, M., Baba, I., Nakabayashi, K, Kato, N., Sasazuki, T., Shirasawa, S.
    • Journal Title

      J. Hum. Genet. 52

      Pages: 978-984

    • NAID

      10020022213

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16065101
  • [Journal Article] DOCK2 is required in T cell precursors for development of Valpha14 NK T cells.2006

    • Author(s)
      Sasazuki T(10番目:全11名)
    • Journal Title

      J Immunol 176(8)

      Pages: 4640-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Association of Polycomb group SUZ12 with WD-repeat protein MEP50 that binds to histone H2A selectively in vitro.2006

    • Author(s)
      Furuno, K., Masatsugu, T., Sonoda, M., Sasazuki, T., Yamamoto, K.
    • Journal Title

      Biochem. Biphys. Res. Commun. 345

      Pages: 1051-1058

    • Data Source
      KAKENHI-PROJECT-16065101
  • [Journal Article] A functional variant in FcRL3, encoding Fc Receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.2005

    • Author(s)
      Shirasawa S(5番目), Sasazuki T(22番目:全23名)
    • Journal Title

      Nature Genet. 37(5)

      Pages: 478-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Role of epiregulin in peptidoglycan-induced proinflammatory cytokine production by antigen presenting cells. Biochem Biophys2005

    • Author(s)
      Sugiyama, S., Nakabayashi, K., Baba, I., Sasazuki, T., Shirasawa, S
    • Journal Title

      Res Commun 337

      Pages: 271-274

    • Data Source
      KAKENHI-PROJECT-16065101
  • [Journal Article] Role of epiregulin in peptidoglycan-induced proinflammatory cytokine production by antigen presenting cells.2005

    • Author(s)
      Sasazuki T(4番目), Shirasawa S(5番目:全5名)
    • Journal Title

      Biochem. Biophys. Res. Commun. 337(1)

      Pages: 271-274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Journal Article] Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.2004

    • Author(s)
      Shirasawa S, Sugiyama S, Baba I, Inokuchi J, Sekine S, Ogino K, Kawamura Y, Dohi T, Fujimoto M, Sasazuki T.
    • Journal Title

      Proc Natl Acad Sci USA 101・38

      Pages: 1391-1396

    • Data Source
      KAKENHI-PROJECT-16065101
  • [Presentation] The flanking region of cedar pollen peptide in complex with HLA-DP5 facilitates T-cell activation.2016

    • Author(s)
      Kusano, S., Ueda, S., Hamana, H., Kishi, H., Muraguchi, A., Ohsawa, N., Wakiyama, M., Yoshikai, Y., Yamada, H., Yamamoto, K., Kukimoto-niino, M., Nishimura, Y., Shirouzu, M., Sasazuki, T. and Yokoyama, S.
    • Organizer
      16th International Congress of Immunology (ICI2016)
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2016-08-21
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-16H06500
  • [Presentation] Epistatic interaction between protective HLA alleles and susceptible HLA-DP allele in autoimmune thyroid disease.2012

    • Author(s)
      Sasazuki T
    • Organizer
      16th International HLA and Immunogenetics Workshop and Conference.
    • Place of Presentation
      Liverpool, England
    • Year and Date
      2012-05-28
    • Data Source
      KAKENHI-PLANNED-22133009
  • [Presentation] HLA controls the clinical difference, overlap, and conversion between Graves disease and Hashimoto thyroiditis.2012

    • Author(s)
      Sasazuki T
    • Organizer
      Novo nordisk innovation summit.
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2012-04-17
    • Invited
    • Data Source
      KAKENHI-PLANNED-22133009
  • [Presentation] Immunogenetic risk factors for autoimmune thyroid disease (ZFAT, FcRL3 and HLA).2012

    • Author(s)
      Sasazuki T
    • Organizer
      14th International Congress of Immunology.
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2012-08-22
    • Invited
    • Data Source
      KAKENHI-PLANNED-22133009
  • [Presentation] HLA in unrelated hematopoietic stem cell transplantation - high risk alleles mismatching in HSCT.2007

    • Author(s)
      Sasazuki T
    • Organizer
      Euroconference, Leiden
    • Place of Presentation
      the Netherlands
    • Data Source
      KAKENHI-PROJECT-17019069
  • [Presentation] A zinc finger protein ZFAT controls AITD through regulating the expression of immune related genes.2006

    • Author(s)
      Sasazuki T
    • Organizer
      第36回日本免疫学会総会・学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17019069
  • 1.  KIMURA Akinori (60161551)
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  • 2.  NISHIMURA Yasuharu (10156119)
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  • 3.  FUKUI Yoshinori (60243961)
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  • 4.  KAMIKAWAJI Nobuhiro (90224659)
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  • 5.  KISHIMOTO Tadamitsu (10093402)
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  • 6.  OKUMURA Ko (50009700)
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  • 7.  INOKO Hidetoshi (10101932)
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  • 8.  YAMAMOTO Ken (60274528)
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  • 10.  SHIRASAWA Senji (10253535)
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  • 13.  KATAGIRI Makoto (10041823)
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  • 14.  TANIGUCHI Masaru (80110310)
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  • 58.  TAKAI Yoshimi (60093514)
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  • 59.  MINATO Nagahiro (40137716)
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  • 66.  TOKUNAGA Katsushi (40163977)
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  • 69.  平山 兼二 (60189868)
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  • 73.  SAKAGUCHI Nobuo (70192086)
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  • 77.  HORINOUCHI Sueharu (80143410)
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  • 78.  SHIMURA Yoshiro (60025426)
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  • 79.  YAMADA Yasuyuki (50026415)
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  • 80.  KARUBE Isao (50089827)
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  • 81.  KOSEKI Haruhiko (40225446)
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  • 82.  HAYASHIDA Kazuhiro (60180981)
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  • 83.  山泉 克 (70107093)
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  • 84.  雨宮 浩 (80009563)
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  • 88.  渋谷 正史 (10107427)
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  • 158.  OHGA Shinsaku (60233053)
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  • 345.  TSUJI Federick
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 346.  FORSEN Karl
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 347.  COOPER Jonathan
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 348.  HAGAN Iain
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 349.  ROBERTS Gordon
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 350.  NAKASEKO Nobuyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 351.  DUMAS C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 352.  SCHELLER Frieder
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 353.  DELSENY Michel
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 354.  MATHIS Diane
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 355.  BENOIST Christophe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 356.  MALISSEN Bernard
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 357.  BALLING Rudolf
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 358.  RAJEWSKY Klaus
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 359.  和田 雅人
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 360.  スレイマン C.W.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 361.  ラスキー R.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 362.  シュミット R.D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 363.  マリッセン B.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 364.  JONES Sarah
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 365.  MCMICHEAL An
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 366.  MATHIS D.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 367.  BENOIST C
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 368.  PIATIGORSKY ジェイ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 369.  MARTY J.L.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 370.  THOMPSON C.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 371.  GOSSLER A
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 372.  KROPSHOTER H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 373.  KROPSHOFER Harald
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 374.  KROPSHOFER H
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 375.  HAMMERLING G
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 376.  VAN Snick J.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 377.  MITCHISON N.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 378.  BORNKAMM G.W
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 379.  CHEIN K.R.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 380.  HERZENBERG L
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 381.  遠山 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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