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HORINOUTI Sueharu  堀之内 末治

ORCIDConnect your ORCID iD *help
… Alternative Names

堀ノ内 末治  ホリノウチ スエハル

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Researcher Number 80143410
External Links
Affiliation (based on the past Project Information) *help 2009: 東京大学, 大学院・農学生命科学
2008 – 2009: 東大, 農学生命科学研究科, 教授
2007: The University of Tokyo, 大学院・農学生命科学研究科, 教授
2006: 東京大学, 大学院農学生命科学研究科, 教授
1996 – 2005: 東京大学, 大学院・農学生命科学研究科, 教授 … More
1996: 東京大学, 農学生命科学系研究科, 教授
1995 – 1996: Tokyo Univ., 農業生命科学研究所, 教授
1995: 東京大学, 農学生命科学研究科, 教授
1994 – 1995: UNIV.of TOKYO,DEPT.OF AGRICULTURE PROFESSOR, 農学部, 教授
1987 – 1993: 東京大学, 農学部, 助教授
1986: 東京大学, 農学部, 助手 Less
Review Section/Research Field
Principal Investigator
応用微生物学・応用生物化学 / Biological Sciences / Applied microbiology / 発酵・醸造 / 応用微生物学・発酵学
Except Principal Investigator
発酵・醸造 / 応用微生物学・発酵学 / Biological Sciences / 応用微生物学・応用生物化学 / Bioorganic chemistry
Keywords
Principal Investigator
放線菌 / 形態分化 / 二次代謝 / A-ファクター / 抗生物質生産 / Streptomyces griseus / Streptomyces / A-factor / 抗生物質 / morphogenesis … More / タンパク質リン酸化 / 自己調節因子 / ゲノム / Secondary Metabolism / Japan-UK Joint Study / Signal transduction / コンビナトリアル生合成 / 遺伝子発現 / カルモジュリン / protein phosphorylation / genome / gene expression / antibiotic biosynthesis / ストレプトマイシン / スレオニンキナーゼ / セリン / 転写因子 / アポトーシス / secondary metabolism / microbial hormone / X-ray chrystallography / A-factor receptor / 微生物ホルモン / A-ファクターレセプター / X線結晶構造 / acetic acid resistance / acetic acid fermentation / 挿入配列 / 酢酸耐性 / 食酢醸造 / X-ray crystallography / Morphorogical Differentiation / Receptor Protein / X線結晶構造解析 / レセプター蛋白 / Sterepromyces griseus / Morphological Differentiation / Molecular Breeding / Genetic Engineering / Antibiotics Production / Molecular Biology / 分子育種 / 遺伝子工学 / 分子生物学 / Steptomyces / Mucor pusillus / Host-vector system / Protein engineering / Mucor rennin / Milk-clotting enzyme / ムコールペプシン / Rhigomucor pusillus / 部位特異的変異法 / 蛋白質工学 / ムコールプシルス / 宿主-ベクター系 / 蛋白工学 / ムコールレンニン / 凝乳酵素 / Morphogenesis / Antibiotic / Utoregulator / Streptomycetes / シグナル伝達 / Protein phosphorylation / Antibiotic production / 蛋白質のリン酸化 / 情報伝達機構 / クローニング / 胞子 / 化学調節物質 / カルバペネム / Streptomyves griseus / Nocardia farcinia / チトクロームP-450 / A-ファクター制御カスケード / Nocardia farcinica / Streptomyces avermitilis / ゲノム配列 / 遺伝子発現制御 / 物質生産 / 二次代謝産物 / Streptomyces coelicolor A3(2) / 胞子の出芽 / Streptomyces ambofaciens / Streptomyces coelicolor / カルシウム結合タンパク質 / ストレプトミセス・グリセウス / 翻訳伸長因子 / カルシウム結合タンパク / ストレプトミセス・グリスウス / 発酵生産 / フラボノイド / 人工生合成遺伝子 / 応用微生物 / バイオテクノロジー / 形態形成 / ゲノムライブラリー / 有用物質生産 / 遺伝子操作 / カルコン合成酵素 / ポリケタイド / 1,3,6,8-tetrahydroxynaphthalene / マロニルCoA / CHS / afsR遺伝子 / 放線菌の二次代謝 / レセプタ-蛋白 / A-ファクタ- / <afsR>___ー遺伝子 / 蛋白リン酸化 / 胞子形成 / Aーファクタ- … More
Except Principal Investigator
細胞周期 / ヒストンアセチル化 / SCOP / FK228 / HDAC / symbiosis / Biosensor / NMR / 凝乳酵素 / 絶対共生細菌 / 共生 / トラポキシン / トリコスタチン / 分裂酵母 / セルラーゼ / レプトマイシン / エタノ-ル / Saccharomyces cerevisiae / キシロ-ス / セルラ-ゼ / キシラン / リグニンペルオキシダ-ゼ / 爆砕 / リグノセルロ-ス / tryptophan / heat-stable enzyme / thermophile / cloning / gene / tryptophanase / 耐熱性 / 発現 / トリプトファン / 耐熱性酵素 / 好熱菌 / クローン化 / 遺伝子 / トリプトファナーゼ / Enzyme activity / Site-directed mutagenesis / Inclusion body / Prochymosin / チロシン77 / 部位指定変異 / 酸性プロテアーゼ / inclusion body / 蛋白質工学 / 酵素活性 / Site directed mutagenesis / inclusior body / プロキモシン / THIOL / DRUG DESIGN / CYCLIC TETRAPEPTIDES / MICROTUBULE / ACETYLATION / クロマチン / 転写制御 / ラディシコール / グルタチオン / ヒストン / チューブリン / 酸化還元 / ヒストンデアセチラーゼ / エンドサイトーシス / プロドラッグ / チオール / ドラッグデザイン / 環状テトラペプチド / 微小管 / アセチル化 / Transcriptional factor / Crystallin gene / Polycomb genes / Transgenics / B cell / Immunological tolerance / T cell / 転写因子 / 有機リン系農薬センサー / 水晶体特異的遺伝子発現 / ポリコ-ム遺伝子 / 発生工学 / B細胞 / 免疫寛容 / T細胞 / 16 sDNA / growth factor / 絶体共生細菌 / 16sDNA / Symbiobacterium / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 温度感受性突然変異体 / ATPase / 免疫病 / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / unsaturated fatty acid synthetase / caroxypeptidase / chitin synthetase / taka-amylaseA / chymosin / cellulase / amine oxidase / gene structure and expression in filamentous fingi / キチン合成・分解酵素 / チトクロームP-450 / タカアミラーゼA遺伝子 / グリコシルトランスフェラーゼ遺伝子 / 糸状菌 / タカアミラーゼA / キチン合成酵素 / カルボキシペプチダーゼ / 不飽和脂肪酸合成酵素 / アミン酸化酵素 / 糸状菌遺伝子の構造と発現制御 / クローニング / β-チロシナーゼ / 遺伝子クロ-ニング / トリプトファナ-ゼ / β-チロシナ-ゼ / 好熱性共生細菌 / 核外移行 / サイクリン依存症キナーゼ / シグナル伝達 / アポトーシス / 遺伝子発現 / MAPキナーゼ / CDK / 細胞死 / CRM1 / 核外移行シグナル / 代謝制御 / バイオテクノロジー / 生合成工学 / 活性天然物 / 生合成遺伝子 / 生合成酵素 / 二次代謝 / 多剤耐性 / 倍数性 / preussin / radicicol / Hsp70 / cdc mutant / Preussin / Radicicol / two-hybrid system / Ras / T細胞受容体 / シアリダーゼ / トランスジェニックマウス / Gal転移酵素 / 癌細胞 / シアル酸転移酵素 / ベイシジン / GnT-III / 糖タンパク質 / 糖鎖 / ミドカイン / シアリルルイスX / α1-6フコシルトランスフェラーゼ / 遺伝子クローニング / 細胞導入 / 糖鎖遺伝子 / 染色体高次構造 / チロシンキナーゼ / がん遺伝子 / アクチンストレスファイバー / キシロース / キシラーゼ / 抽出発酵 / パーオキシダーゼ / 水蒸気爆砕 / エタノール / リグノセルロース / チロシンキナ-ゼ / ラディシコ-ル / 多剤耐性遺伝子 / P‐糖蛋白質 / 多倍体 / プロテインキナ-ゼ / リフォ-ルデイング / リフォ-ルディング / 反応遷移状態 / サブサイト / 部位特異的変異 / 蛋白工学 / ムコ-ルレンニン / キモシン / アスパラギン酸プロテア-ゼ / Flow cytometry / Protein kinase / Histone acetylation / Staurosporine / Leptomycin / Trichostatin / Cell cycle control Less
  • Research Projects

    (42 results)
  • Research Products

    (57 results)
  • Co-Researchers

    (140 People)
  •  放線菌の二次代謝、形態分化を司る制御機構の統括的解明Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied microbiology
    • Research Institution
      The University of Tokyo
  •  High efficient production of secondary metabolites on the basis of genomes of StreptomycesPrincipal Investigator

    • Principal Investigator
      IKEDA Haruo, 堀之内 末治
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kitasato University
      The University of Tokyo
  •  放線菌ストレプトミセス・グリセウスのA‐ファクター制御カスケードの網羅的解明Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  微生物カルモジュリン:放線菌における増殖、形態分化の制御Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      The University of Tokyo
  •  放線菌ストレプトミセス・グリセウスのA-ファクター制御カスケードの網羅的解明Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  放線菌ストレプトミセス・グリセウスのA-ファクター制御カスケードの網羅的解明Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  カルモジュリン制御のプロトタイプ:放線菌における二次代謝、形態分化の制御Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  放線菌ストレプトミセス・グリセウスのゲノム解析のための基盤研究Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  人工的生合成遺伝子クラスターを賦与した放線菌によるフラボノイド化合物の発酵生産Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Comprehensive study on regulatory systems for the initiation of secondary metabolism and morphological development in StreptomycesPrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  放線菌ストレプトミセス・グリセウスのゲノム解析のための基盤整備Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  DEVELOPMENT OF CANCER THERAPEUTICS BASED ON REGULATION OF CHROMATIN STRUCTURE AND FUNCTION

    • Principal Investigator
      YOSHIDA Minoru
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      RIKEN
      The University of Tokyo
  •  放線菌のカルコン合成酵素様遺伝子を用いたフラボノイド醗酵生産の基盤研究Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Studies on the structure and function of A-factor receptor based on its X-ray crystallographic structurePrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      THE UNIVERSITY OF TOKYO
  •  コンビナトリアル生合成法によるフラボノイドの発酵生産Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  細胞周期と細胞死のシグナル伝達阻害剤の開発とその分子作用機構

    • Principal Investigator
      吉田 稔
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Japan-UK Joint Study on Molecular Genetics of StreptomycesPrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Studies on A-factor receptor protein involved in secondary metabolism and morphorogical differentiation in Streptomyces griseusPrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Study on the genetics of acetic acid bacteria for the efficient vinegar productionPrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  細胞周期の分子機構とその抑制剤の開発

    • Principal Investigator
      吉田 稔
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  天然物の生合成機構とその人為的制御

    • Principal Investigator
      柿沼 勝巳
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Bioorganic chemistry
    • Research Institution
      Tokyo Institute of Technology
  •  Regulation of secondary metabolism and cell differentiation by A-factor and protein phosphorylation in Streptomyces.Principal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Improvement of milk-clotting enzyme, Mucor rennin, by protein engineering and 「genetic engineering.Principal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      The University of Tokyo
  •  Analysis of a growth factor of a thermophilic symbiotic bacteria

    • Principal Investigator
      BEPPU Teruhiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Nihon University
  •  新しいG1,G2期特異的細胞周期阻害剤の探索とそれを用いた増殖制御機構の解析

    • Principal Investigator
      別府 輝彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  糖鎖遺伝子の特異性

    • Principal Investigator
      谷口 直之
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Genetical and biochemical analyzes of multiple functions in filamentous fungi

    • Principal Investigator
      TSUKAGOSHI Norihiro
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      NAGOYA UNIVERSITY
  •  Regulation of secondary metabolism and cellular differentiation by A-factor and signal transduction systems in StreptomycesPrincipal Investigator

    • Principal Investigator
      HORINOUCHI Sueharu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      The University of Tokyo
  •  リグノセルロ-ス資源の生物燃料への変換

    • Principal Investigator
      吉田 敏臣
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  新しいG1,G2期特異的細胞周期阻害剤の探索とそれを用いた増殖制御機構の解析

    • Principal Investigator
      別府 輝彦
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  リグノセルロ-ス資源の生物燃料への変換

    • Principal Investigator
      吉田 敏臣
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  新しいG_1,G_2期特異的細胞周期阻害剤の探索とそれを用いた増殖制御機構の解析

    • Principal Investigator
      BEPPU Teruhiko
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  ウシキモシンおよびムコ-ルレンニンの蛋白工学的研究

    • Principal Investigator
      別府 輝彦
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      応用微生物学・発酵学
    • Research Institution
      The University of Tokyo
  •  リグノセルロース資源の生物燃料への変換

    • Principal Investigator
      吉田 敏臣
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  放線菌の化学調節物質Aーファクタ-をめぐる調節ネットワ-クに関する研究Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      発酵・醸造
    • Research Institution
      The University of Tokyo
  •  絶対共生細菌の生産する耐熱性β-チロシナ-ゼ遺伝子のクロ-ン化と共生機構の解明

    • Principal Investigator
      別府 輝彦
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      発酵・醸造
    • Research Institution
      The University of Tokyo
  •  カルバペネム生産性放線菌における微量調節因子に関する研究Principal Investigator

    • Principal Investigator
      堀之内 末治
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      発酵・醸造
    • Research Institution
      The University of Tokyo
  •  諸外国におけるバイオサイエンスの研究動向調査

    • Principal Investigator
      軽部 征夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
  •  Improvement and reconstitution of procymosin by recombinant DNA techniques

    • Principal Investigator
      BEPPU Teruhiko.
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      発酵・醸造
    • Research Institution
      The University of Tokyo
  •  Cloning of a gene for heat-stable tryptophanase produced by an obligatorily symbiotic and thermophilic bacterium.

    • Principal Investigator
      UOZUMI Takeshi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      発酵・醸造
    • Research Institution
      The University of Tokyo

All 2009 2008 2007 2006 2005 2004 2003 2002 2001

All Journal Article Presentation Book

  • [Book] Chemical Communication among Bacteria2008

    • Author(s)
      Sueharu Horinouchi
    • Total Pages
      15
    • Publisher
      American Society for Microbiology
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Book] 「農芸化学の事典」(鈴木昭憲, 荒井綜一 編)2003

    • Author(s)
      堀之内末治
    • Publisher
      朝倉書店、東京
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Book] Encyclopedia of Agricultural Chemistry2003

    • Author(s)
      Sueharu Horinouchi
    • Publisher
      Asakura-shoten
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] Identification and gene disruption of small noncoding RNAs in Streptomyces griseus.2009

    • Author(s)
      Tezuka T, Hara H.Ohnishi Y, Horinouchi S
    • Journal Title

      J.Bacteriol. 191

      Pages: 4896-4904

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-producing type III polyketide synthases.2009

    • Author(s)
      Miyanaga, A., Horinouchi, S.
    • Journal Title

      J. Antibiot 62

      Pages: 371-376

    • NAID

      10030635764

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] CebR as a master regulator for cellulose/cellooligosaccharide catabolism affects morphological development in Streptomyces griseus.2009

    • Author(s)
      Marushima, K., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      J. Bacteriol 191

      Pages: 5930-5940

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Identification and characterization of target genes of the GinI/GinR quorum-sensing system in Gluconacetobacter intermedius.2009

    • Author(s)
      Iida A, Ohnishi Y, Horinouchi S
    • Journal Title

      Microbiol. 155

      Pages: 3021-3032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.2009

    • Author(s)
      Nakano, C., Ozawa, H., Akanuma, G., Funa, N., Horinouchi, S.
    • Journal Title

      J. Bacteriol 191

      Pages: 4916-4923

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Dynamic changes in the extracellular proteome caused by absence of a pleiotropic regulator AdpA in Streptomyces griseus.2009

    • Author(s)
      Akanuma, G., Hara, H., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      Mol. Microbiol 73

      Pages: 898-912

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Enzymatic synthesis of bis-5-alkylresorcinols by resorcinol-Producing type III polyketide synthases.2009

    • Author(s)
      Miyanaga A, Horinouchi S
    • Journal Title

      J.Antibiot. 62

      Pages: 371-376

    • NAID

      10030635764

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] DNA microarray analysis of global gene regulation by A-factor in Streptomyces griseus.2009

    • Author(s)
      Hara, H., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      Microbiology 155

      Pages: 2197-2210

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Combinatorial biosynthesis of plant medicinal polyketides by microorganisms. Curr.2009

    • Author(s)
      Horinouchi, S.
    • Journal Title

      Opin. Chem. Biol. 13

      Pages: 197-204

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.2009

    • Author(s)
      Nakano C, Ozawa H, Akanuma G, Funa N, Horinouchi S
    • Journal Title

      J.Bacteriol. 191

      Pages: 4916-4923

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Identification and gene disruption of small noncoding RNAs in Streptomyces griseus.2009

    • Author(s)
      Tezuka, T., Hara, H., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      J. Bacteriol 191

      Pages: 4896-4904

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.2009

    • Author(s)
      Katsuyama Y, Kita T, Funa N, Horinouchi S
    • Journal Title

      J.Biol.Chem. 284

      Pages: 11160-11170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase.2009

    • Author(s)
      Awakawa T, Yokota K, Funa N, Doi F, Mori N, Watanabe H, Horinouchi S
    • Journal Title

      Chem.Biol. 161

      Pages: 613-623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.2009

    • Author(s)
      Katsuyama, Y., Kita, T., Funa, N., Horinouchi, S.
    • Journal Title

      J. Biol. Chem. 284

      Pages: 11160-11170

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Combinatorial biosynthesis of Plant medicinal polyketides by microorganisms.2009

    • Author(s)
      Horinouchi S
    • Journal Title

      Curr.Opin.Chem.Biol. 13

      Pages: 197-204

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.2009

    • Author(s)
      Katsuyama, Y., Kita, T., Horinouchi, S.
    • Journal Title

      FEBS Lett. 583

      Pages: 2799-2803

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Physically discrete beta-lactamase-type thioesterase catalyzes product release in atrochrysone synthesis by iterative type I polyketide synthase.2009

    • Author(s)
      Awakawa, T., Yokota, K., Funa, N., Doi, F., Mori, N., Watanabe, H., Horinouchi, S.
    • Journal Title

      Chem. Biol. 16

      Pages: 613-623

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Identification and characterization of multiple curcumin synthases from the herb Curcuma longa.2009

    • Author(s)
      Katsuyama Y, Kita T, Horinouchi S
    • Journal Title

      FEBS Lett. 583

      Pages: 2799-2803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] CebR as a master regulator for cellulose/cellooligosaccharide catabolism affects morphological development in Streptomyces griseus.2009

    • Author(s)
      Marushima K, Ohnishi Y, Horinouchi S
    • Journal Title

      J.Bacteriol. 191

      Pages: 5930-5940

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Conditionally positive effect of the TetR-family transcriptional regulator AtrA on streptomycin production by Streptomyces griseus.2008

    • Author(s)
      Hirano, S., Tanaka, K., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      Microbiology 154

      Pages: 905-914

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] A novel pair of terminal protein and telomere-associated protein for replication of the linear chromosome of Streptomyces griseus.2008

    • Author(s)
      Suzuki, H., Marushima, K., Ohnishi, Y., Horinouchi, S.
    • Journal Title

      Biosci. Biotechnol. Biochem 72

      Pages: 2973-2980

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article]2008

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Chemical Communication among Bacteria(American Society for Microbiology)

      Pages: 363-377

    • Data Source
      KAKENHI-PROJECT-19208009
  • [Journal Article] Direct transfer of starter substrates from type I fatty acid synthase to type III polyketide synthases in phenolic lipid synthesis.2008

    • Author(s)
      Miyanaga, A., Funa, N., Awakawa, T., Horinouchi, S.
    • Journal Title

      Proc. Natl. Acad. Sci. 105

      Pages: 871-876

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Phenolic lipids synthesized by type III polyketide synthase confer penicillin resistance on Streptomyces griseus.2008

    • Author(s)
      Funabashi, M., Funa, N., Horinouchi, S.
    • Journal Title

      J. Biol. Chem. 283

      Pages: 13983-13991

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Production of curcuminoids by Escherichia coli containing an artificial biosynthesis pathway.2008

    • Author(s)
      Katsuyama, Y., Matsuzawa, M., Funa, N., Horinouchi, S.
    • Journal Title

      Microbiology 154

      Pages: 2620-2628

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Genome sequence of the streptomycin-producing microorganism Streptomyces griseus IFO 13350.2008

    • Author(s)
      Ohnishi, Y., Ishikawa, J., Hara, H., Suzuki, H., Ikenoya, M., Ikeda, H., Yamashita, A., Hattori, M., Horinouchi, S.
    • Journal Title

      J. Bacteriol 190

      Pages: 4050-4060

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] 有用遺伝子の天然保存庫としての放線菌2006

    • Author(s)
      堀之内末治
    • Journal Title

      学術月報 58

      Pages: 762-766

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] 放線菌機能の制御、発掘、応用2005

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 63

      Pages: 11-16

    • NAID

      10014081480

    • Data Source
      KAKENHI-PROJECT-16013210
  • [Journal Article] Streptomyces as a reservoir of useful genes (in Japanese).2005

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Gakujutu-Geppo 58

      Pages: 762-766

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 有用遺伝子の天然保存庫としての放線菌2005

    • Author(s)
      堀之内末治
    • Journal Title

      学術月報 58

      Pages: 762-766

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 放線菌機能の制御、発掘、応用2005

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 63

      Pages: 11-16

    • NAID

      10014081480

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 放線菌機能の制御、発掘、応用2005

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 63

      Pages: 11-16

    • NAID

      10014081480

    • Data Source
      KAKENHI-PROJECT-17019009
  • [Journal Article] Regulation, mining and polishing of Streptomyces functions (in Japanese).2005

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Bioscience & Industry 63

      Pages: 11-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 有用物質生産の場としての放線菌2004

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 59

      Pages: 526-529

    • NAID

      10007291231

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 「目でみるバイオ」 放線菌A-ファクター受容体の構造と機能2004

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 62

      Pages: 503-504

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] Structure and function of the A-factor receptor (in Japanese).2004

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Bioscience & Industry 62

      Pages: 503-504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 「目でみるバイオ」放線菌A-ファクター受容体の構造と機能2004

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 62

      Pages: 503-504

    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 「目でみるバイオ」放線菌A-ファクター受容体の構造と機能2004

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 62

      Pages: 503-504

    • Data Source
      KAKENHI-PROJECT-16013210
  • [Journal Article] AfsR as an integrator of signals that are sensed by multiple serine/threonine kinases in Streptomyces coelicolor A3(2).2003

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      J.Ind.Microbiol.Biotechnol. 30

      Pages: 462-467

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 放線菌の真核型キナーゼは飾りではなく生育必需品2003

    • Author(s)
      堀之内末治
    • Journal Title

      バイオサイエンスとインダストリー 61

      Pages: 330-331

    • NAID

      80015955943

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] Eukaryotic-type protein kinases in Streptomyces are never accessories but necessaries for health growth (in Japanese).2003

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Bioscience & Industry 61

      Pages: 330-331

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus.2002

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Front, Biosci. 7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] A microbial hormone, A-factor, as a master switch for morphological differentiation and secondary metabolism in Streptomyces griseus.2002

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Front.Biosci. 7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] 原核と真核の境界微生物としての放線菌の形態分化2002

    • Author(s)
      堀之内末治
    • Journal Title

      日本農芸化学会誌 76

      Pages: 937-939

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] Morphogenesis of Streptomyces, a boundary microorganism (in Japanese).2002

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Nippon Nogeikagaku-kaishi 76

      Pages: 937-939

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] Streptomyces as a factory for production of useful substances (in Japanese).2001

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      Bioscience & Industry 59

      Pages: 526-529

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] The A-factor regulatory cascade and cAMP in the regulation of physioligical and morpholigical development in Streptomyces griseus.2001

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      J. Ind. Microbiol. Biotechnol. 27

      Pages: 177-182

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Journal Article] The A-factor regulatory cascade and cAMP in the regulation of physiological and morphological development in Streptomyces griseus.2001

    • Author(s)
      Sueharu Horinouchi
    • Journal Title

      J.Ind.Microbiol.Biotechnol. 27

      Pages: 177-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13854005
  • [Presentation] 放線菌遺伝子のコンビナトリアル生合成への利用2007

    • Author(s)
      堀之内末治
    • Organizer
      福山大学グリーンサイエンス研究センター公開講演会-土壌細菌の底力:放線菌と枯草菌-
    • Place of Presentation
      福山大学
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Presentation] コンビナトリアル生合成と微生物2007

    • Author(s)
      堀之内末治
    • Organizer
      豊かな社会を創造する科学技術シンポジウム、長瀬科学技術振興財団
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2007-09-30
    • Data Source
      KAKENHI-PROJECT-17019009
  • [Presentation] コンビナトリアル生合成と微生物2007

    • Author(s)
      堀之内末治
    • Organizer
      豊かな社会を創造する科学技術シンポジウム、長瀬科学技術振興財団
    • Place of Presentation
      大阪国際交流センター
    • Year and Date
      2007-09-30
    • Data Source
      KAKENHI-PROJECT-19208009
  • [Presentation] 放線菌遺伝子のコンビナトリアル生合成への利用2007

    • Author(s)
      堀之内末治
    • Organizer
      福山大学グリーンサイエンス研究センター公開講演会-土壌細菌の底力:放線菌と枯草菌-
    • Place of Presentation
      福山大学
    • Year and Date
      2007-09-15
    • Data Source
      KAKENHI-PROJECT-19208009
  • [Presentation] 「非微生物型」物質の微生物による発酵生産2007

    • Author(s)
      堀之内末治
    • Organizer
      Arnold L. Demain 先生の傘寿を祝う講演会、日本放線菌学会
    • Place of Presentation
      北里研究所
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-19208009
  • [Presentation] 「非微生物型」物質の微生物による発酵生産2007

    • Author(s)
      堀之内末治
    • Organizer
      Arnold L. Demain先生の傘寿を祝う講演会、日本放線菌学会
    • Place of Presentation
      北里研究所
    • Year and Date
      2007-11-30
    • Data Source
      KAKENHI-PROJECT-17019009
  • 1.  BEPPU Teruhiko (80011873)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  YOSHIDA Minoru (80191617)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 3.  OHNISHI Yasuo (90292789)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  NISHIYAMA Makoto (00208240)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  TANIGUCHI Masaru (80110310)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  UOZUMI Takeshi (40011978)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  YASUDA Kunio (30025473)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  IKEDA Haruo (90159632)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 9.  KARUBE Isao (50089827)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  WATANABE Takeshi (40028684)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  吉田 敏臣 (00029290)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  宮川 都吉 (10116676)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  桑原 正章 (40035978)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  沢田 達郎 (80019728)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  SETO Haruo (10013335)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  KAMADA Hiroshi (00169608)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  KISHIMOTO Tadamitsu (10093402)
    # of Collaborated Projects: 2 results
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  • 137.  塚本 義則
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  • 139.  中野 繁
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  • 140.  原口 宏
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