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TSURUO Takashi  鶴尾 隆

ORCIDConnect your ORCID iD *help
Researcher Number 00012667
Affiliation (based on the past Project Information) *help 2009: (財)癌研究会, 癌化学療法センター, 所長
2007: Japanese Foundation For Cancer Research, 癌化学療法センター, 所長
2006: (財)癌研究会, 癌化学療法センター, 所長
1993 – 2005: 東京大学, 分子細胞生物学研究所, 教授
1999 – 2000: 東京大学, 分子細胞生物学研究所, 所長 … More
1999 – 2000: 東京大学, 分子細胞生物学研究所・分子生物活性研究分野, 教授
1999: Dept. Surgery, Faculty of Medicine, University of Tokyo, Professor, 分子生物学研究所, 教授
1998: 東京大学, 分子細胞生物学, 教授
1997: 東京大学, 分子細胞生物学・研究所, 教授
1996: 東京大学, 分子細胞学研究所, 教授
1993: 東京大学, 応用微生物学研究所, 教授
1989 – 1992: 東京大学, 応用微生物研究所, 教授
1991: (財)癌研究会, 癌化学療法センター, 部長
1991: 東京大学応用微生物研究所, 教授
1989 – 1990: 癌研究会, 癌化学療法センター, 部長
1988 – 1990: 東京大学, 応用微生物学研究所, 教授
1988: 癌研, 癌化学療法センター, 部長
1988: 癌研究会, 癌化学療法センター・基礎研究部, 部長
1988: 癌研究会癌化学療法センター, 基礎研究部, 部長
1987: (財)癌研究会, 癌化学療法センター・基礎研究部, 部長
1987: 癌研究所, 化学療法センター, 部長
1986 – 1987: 癌研, 化学療法センター, 部長
1986: (財)癌研究会癌化学療法センター, 基礎研究部, 部長
1986: 癌研究会, その他, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences
Except Principal Investigator
Biological Sciences / 応用薬理学・医療系薬学 / General surgery / Digestive surgery / Chemical pharmacy / 内分泌・代謝学
Keywords
Principal Investigator
耐性遺伝子 / 耐性タンパク / 抗癌剤耐性 / カルシウム拮抗薬 / モノクローナル抗体 / アドリアマイシン / ビンクリスチン / 抗癌剤 / 医療・福祉 / 癌 … More / 癌転移 / アポトーシス / 耐性克服 / 分子標的 / P-糖タンパク / ユビキチン / モノクロ-ナル抗体 / Molecular Target Therapy / Gene Manipulated Animals / Cancer Genome / Support for Young Investigators / International Scientific Exchange / Screening / Research Materials / Cancer / 若手支授 / 研究資材 / 分子標的治療 / 遺伝子操作動物 / がんゲノム / 若手支援 / 国際学術研究交流 / スクリーニング / 研究資料 / がん / カルシウム培抗薬 / シゲナル伝達 / 薬学 / ゲノム / シグナル伝達 / 癌移転 / カルシウム拮抗剤 / トポイソメラ-ゼ / P‐糖タンパク / Pー糖タンパク … More
Except Principal Investigator
KB細胞 / P388白血病 / 制がん剤 / ヒト胃癌細胞 / 薬剤耐性 / 化学療法 / スクリーニング / シグナル伝達 / 増殖因子 / 癌転移 / ランダム・スクリーニング / Yunnan Provience / cytotoxity / Antitumor activity / 雲南植物圏 / 抗酸化活性 / BRM活性 / 雲南植物園 / 細胞毒性 / 抗がん活性 / P53 / p21 / BCL-2 / RAS / APC / 多剤耐性 / ヒト胃癌細胞株 / 制癌剤 / リゾキシン / サフラマイシン / 癌 / 腫瘍血管 / がん遺伝子 / 細胞接着 / 分子標的治療 / 放射線治療 / MDR1mRNA発現 / 多剤耐性遺伝子(MDR1) / 多剤耐性(MDR)腫瘍 / チロシンキナ-ゼ / チロシンリン酸化 / IGFーI / HIV / エイズ / 超ラセン / Lymphokine / Immune Desponse / T Cell Growth / Tumor Antigen / Tumor Supressor Gene / Tumor Promoter / Viral Oncogene / Oncogene / リンフォカイン / 免疫応答 / T細胞の増殖 / 腫瘍抗原 / がん抑制遺伝子 / 発がんプロモ-タ- / ウイルス発がん / Cancer Treatment / Monoclonal Antibodies / Endothelial Cells / Tumor Endothelium / モノクローナル抗体 / 血管内皮細胞 / 治療 / 癌治療 / 抗体 / 内皮細胞 / Protective factors / Risk factors / Cancer prevention / Clinical epidemiology / Molecular epidemiology / Case-control study / Cohort study / Ethnoepidemiology / 症例・対照研究 / 大規模共同研究 / 国際比較研究 / 宿主・環境要因 / 宿主・環境交互作用 / コホート研究 / 遺伝子・環境交互作用 / 広報活動 / 予防啓発 / 分子疫学コーホート / 分析疫学 / 予防 / 危険・防御要因 / 臨床疫学 / 分子疫学 / 症例対照研究 / コーホート研究 / 民族疫学 / emdin / kojou / cell cycle inhibition / Antioxdative activity / RRM activity / エモデイン / 虎杖 / 細胞周期阻害 / ferulic acid / Kamebakurin / Benibana / Antioxidative activity / BRM activity / フェルラル酸 / カメバカウリン / 紅花 / Chemotherapy / BCL-XL / Gene mutation / Colorectal cancer / DCC / Cyclin / Apoptosis / Dihydropyrimidine dehydrogenase / Bcl-2 / 癌抑制遺伝子 / 細胞周期 / アポトーシス / replication error / APC遺伝子 / BCC-XC / p53 / Bcl-xL / 遺伝子 / 大腸癌 / MRSA / MDR modifier / mechanism of MDR / tubulin / antitumor / P-glycoprotein / multidrug-resistance / natural products / 耐性菌 / 耐性克服物質 / 薬剤耐性発現機構 / チューブリン / 抗腫瘍活性 / P-糖蛋白質 / 天然物 / エトポシド / カンプトテシン / DNAトポイソメラーゼ / ベラパミール / Epiderstatin / カンプトテシンのヒドロキシ高級脂肪酸エステル / アンスラサイクリンのモルホリノ誘導体 / CPT-11 / 細胞周期特異的抗腫瘍性 / O2-3D / クロモマイシン / 低毒性アンスラサイクリン / バクトボリン / アスカマイシン,スタボマイシン / 癌細胞の薬剤耐性機構 / モルフオリノロドロキシカルミノマイシン / 胃癌細胞株 / ゲニスチン / スタボマイシン / アスカマイシン / 薬剤耐性癌細胞 / アンスラサイクリン誘導体 / 抗癌剤の心毒性 / 新しい物療法 / トランスレーショナルリサーチ / 分子創薬 / トランスレーショナル・リサーチ / 新しい物理療法 / ドラッグデリバリーシステム / 分子標的 / レセプター / ATP / 遺伝病 / 構造解析 / 膜タンパク質 / 動脈硬化 / チャネル / ABCタンパク質 / トランスポーター / 糖尿病 / コレステロール / 生活習慣病 / ABC蛋白質 / Annexin II / 破骨細胞活性化因子 / 骨吸収 / 破骨細胞 / 乳癌 / AnnexinII / 骨転移 / がん研究の推進 / 白血病 / 細胞死 / 先端的研究 / 遺伝子治療 / 免疫療法 / がん診断 / がん治療 / がんの放射線療法 / がん化学療法 / がんの分子標的治療 / がんの遺伝子治療 / がん免疫 / がんの質的診断法 / がんの早期診断法 / cohort / project / support / steering / cancer research / 成果とりまとめ / 文部省がん研究 / ヒト癌培養細胞 / P388マウス白血病 / cyclosporin A(CsA)誘導体 / MDR癌の免疫療法 / 血液脳関門 / 抗P-gp抗体 / P糖蛋白(P-gp) / バイオサイエンス / がん / IL-I / TNF-α / サイトカイン / シアリルLe^x / 類洞内皮細胞 / 接着 / 肝転移 / rhodamino123effluxtest / 免疫磁気ビーズ(MACS)法 / ヒト・マウスキメラ抗体 / 抗P-gp抗体(MRK16,C219,U1C) / P糖蛋白(P-glycoprotain;P-gp) / carbovir(カルボヴィ-ル)誘導体(BCA) / BenanomicinA(ベナノマイシンA) / Alborixin(アルボリキシン) / ポリエ-テル抗生物質 / 増殖抑制 / gag抗原 / 単クロ-ン抗体 / ヒト免疫不全ウイルス / ラ・ダム・スクリ-ニング / ホスファチジルイノシト-ル3キナ-ゼ / magneticーaffinity cell sorring(MACS)法 / ヒトマウスキメラ抗体 / mdr1mRNA発現 / 多剤耐性遺伝子(mdr1) / 抗Pーgp抗体C219 / 抗Pーgp抗体MRK16 / P糖蛋白(Pーglycoprotein;Pーgp) / 多剤耐性腫瘍 / AZT / エネシアスタチンB / キジミシン / 抗生物質 / リポソ-ム / ランダム・スクリ-ニング / 高転移性細胞 / インスリン様増殖因子I / 核マトリックス / DNAトポロジ- / DNAトポイソメラ-ゼ / 単クローン抗体 / NーアセチルベナノマイシンB / ベナノマイシンA / p17 / 抗HIV活性 / 治療剤 / タンパク精製 / ボイデンチェンバー / 細胞運動促進因子 / トポロジー / DNAトポイソラーゼ Less
  • Research Projects

    (51 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (138 People)
  •  Molecular therapeutics targeting drug-resistance mechanismsPrincipal Investigator

    • Principal Investigator
      TOMIDA Akihiro, 鶴尾 隆
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
      The University of Tokyo
  •  New therapeutic strategies for treatment of cancer based on basic research

    • Principal Investigator
      UEDA Ryuzo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya City University
  •  ABC蛋白の多機能性と生命維持機構

    • Principal Investigator
      植田 和光
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  がん研究の総合的推進に係る研究

    • Principal Investigator
      北川 知行
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  がんの戦略的先端研究

    • Principal Investigator
      渋谷 正史, 吉田 光昭
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  General Promotion of Cancer Research in JapanPrincipal Investigator

    • Principal Investigator
      TSURUO Tahashi
    • Project Period (FY)
      1999 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tokyo
  •  Epidemiologic studies on environmental and host-specific factors for human cancers

    • Principal Investigator
      TAJIMA Kazuo
    • Project Period (FY)
      1999 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center
  •  Development of a New Stragegy for Cancer Treatment by Targeting Tumor Vascular Endothelium Using Monoclonal Antibodies

    • Principal Investigator
      TSUNO Hirokazu
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      The University of Tokyo
  •  Studies of Floral Antitumor Medicines in Yunnan Province

    • Principal Investigator
      NISHIMURA Toshio
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Teikyo University
  •  Studies of Floral Antitumor Medicines in Yunnan Province

    • Principal Investigator
      NISHIMURA Toshio
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Teikyo University
  •  Integrated mutation analysis in colorectal cancer

    • Principal Investigator
      KITAYAMA Joji, 武藤 徹一郎
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Digestive surgery
    • Research Institution
      The University of Tokyo
  •  乳癌細胞におけるAnnexinIIの発現とその骨転移形成過程における意義

    • Principal Investigator
      高橋 俊二
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Search and development for new compounds to overcome drug resistance from natural sources

    • Principal Investigator
      KOBAYASHI Jun'ichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  がん診断治療の基礎研究

    • Principal Investigator
      濱岡 利之
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Osaka University
  •  がん細胞の薬剤感受性と抵抗性の分子機構とその制御Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  難治性癌の薬剤抵抗性の分子機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  モノクロナール抗体遺伝子を用いた耐性癌の基礎的な診断と治療に関する研究

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  モノクロトール抗体,遺伝子を用いた耐性癌の基礎的な診断と治療にする研究

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  大腸癌の肝転移を決定する因子の解析

    • Principal Investigator
      矢守 隆夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  モノクロナ-ル抗体,遺伝子を用いた耐性癌の基礎的な診断と治療に関する研究

    • Principal Investigator
      白川 茂
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Mie University
  •  難治性癌の薬剤抵抗性の分子機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  DNAトポイソメラ-ゼを標的とした癌化学療法開発のための基礎的研究

    • Principal Investigator
      安藤 俊夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  高転移性細胞に対するIGFーIの作用の解析

    • Principal Investigator
      矢守 隆夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  難治性癌の薬剤抵抗性の分子機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  高転移性細胞に対するIGFーIの作用の解析

    • Principal Investigator
      矢守 隆夫
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  バイオサイエンスの進展に基づくがんの重点研究

    • Principal Investigator
      豊島 久真男
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  DNAトポイソメラーゼ(トポ)を標的とした癌化学療法開発のための基礎的研究

    • Principal Investigator
      安藤 俊夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  制がん剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  抗がん剤耐性の分子機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  癌細胞運動促進因子の精製と機能の解析

    • Principal Investigator
      濱田 洋文
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  エイズの総合的基礎研究 柱5.エイズの予防と治療に関する研究

    • Principal Investigator
      上田 重晴
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  制がん剤のスクリ-ニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  エイズの総合的基礎研究 A05 エイズの予防と治療に関する研究

    • Principal Investigator
      上田 重晴
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  制がん剤のスクリ-ニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  エイズの総合的基礎研究.A05エイズの予防と治療に関する研究

    • Principal Investigator
      上田 重晴
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  制がん剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1989 – 1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1989 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  天然物由来制癌物質の探索とその化学的誘導に関する研究

    • Principal Investigator
      瀬戸 治男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  DNAトボイソメラーゼを標的とした癌化学療法のための基礎的研究

    • Principal Investigator
      安藤 俊夫
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Meiji Pharmaceutical University
  •  Information Exchange on Cancer Research with North American Countries

    • Principal Investigator
      YAMAGUCHI Nobuo, 河井 貞明
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  先進諸国におけるエイズの基礎研究に関する調査

    • Principal Investigator
      小高 健
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Overseas Scientific Research
  •  細胞膜に作用する抗生物質の探索と構造-作用相関の研究

    • Principal Investigator
      大岳 望
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  制がん剤耐性機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制がん剤耐性機構とその克服Principal Investigator

    • Principal Investigator
      鶴尾 隆
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  細胞膜に作用する抗癌抗生物質の探索と構造活性相関の研究

    • Principal Investigator
      大岳 望
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  制がん剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1974 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制癌剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1974 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  制癌剤のスクリーニング

    • Principal Investigator
      塚越 茂
    • Project Period (FY)
      1974 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research

All 2009 2008 2007 2005 2003

All Journal Article Presentation Book

  • [Book] がん分子標的治療研究実践マニュアル2009

    • Author(s)
      曽根三郎、鶴尾隆
    • Total Pages
      329
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Book] がんの分子標的治療2008

    • Author(s)
      鶴尾隆
    • Total Pages
      441
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Book] 癌化学療法update2005

    • Author(s)
      西條長宏、鶴尾隆
    • Total Pages
      524
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Dofequidar fumarate sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export2009

    • Author(s)
      Katayama R, Koike S, Sato S, Sugimoto Y, Tsuruo T, Fujita N.
    • Journal Title

      Cancer Sci. 100

      Pages: 2060-8

    • NAID

      10027196750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin2009

    • Author(s)
      Matsuo J, Tsukumo Y, Sakurai J, Tsukahara S, Park HR, Shin-Ya K, Watanabe T, Tsuruo T, Tomida A.
    • Journal Title

      Cancer Sci. 100

      Pages: 327-33

    • NAID

      10025142654

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] A novel endoplasmic reticulum export signal: proline at the +2-position from the signal peptide cleavage site2009

    • Author(s)
      Tsukumo Y, Tsukahara S, Saito S, Tsuruo T, Tomida A.
    • Journal Title

      J Biol Chem. 284

      Pages: 27500-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Acyl-CoA synthetase as a cancer survival factor: its inhibition enhances the efficacy of etoposide2009

    • Author(s)
      Mashima T, Sato S, Okabe S, Miyata S, Matsuura M, Sugimoto Y, Tsuruo T, Seimiya H.
    • Journal Title

      Cancer Sci. 100

      Pages: 1556-62

    • NAID

      10027193846

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation2009

    • Author(s)
      Saito S, Furuno A, Sakurai J, Sakamoto A, Park HR, Shin-Ya K, Tsuruo T, Tomida A.
    • Journal Title

      Cancer Res. 69

      Pages: 4225-34

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions2009

    • Author(s)
      Mashima T, Sato S, Sugimoto Y, Tsuruo T, Seimiya H.
    • Journal Title

      Oncogene 28

      Pages: 9-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy2009

    • Author(s)
      Mashima T, Seimiya H, Tsuruo T.
    • Journal Title

      Br J Cancer. 100

      Pages: 1369-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] PRMT5, a novel TRAIL receptor-binding protein, inhibits TRAIL-induced apoptosis via nuclear factor-kappaB activation2009

    • Author(s)
      Tanaka H, Hoshikawa Y, Oh-hara T, Koike S, Naito M, Noda T, Arai H, Tsuruo T, Fujita N.
    • Journal Title

      Mol Cancer Res. 7

      Pages: 557-69

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Small molecules destabilize cIAP1 by activating auto-ubiquitylation2008

    • Author(s)
      Sekine K, Takubo K, Kikuchi R, Nishimoto M, Kitagawa M, Abe F, Nishikawa K, Tsuruo T, Naito M.
    • Journal Title

      J Biol Chem. 283

      Pages: 8961-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels2008

    • Author(s)
      Morishita D, Katayama R, Sekimizu K, Tsuruo T, Fujita N.
    • Journal Title

      Cancer Res. 68

      Pages: 5076-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Tetraspanin family member CD9 inhibits Aggrus/podoplanin-induced platelet aggregation and suppresses pulmonary metastasis2008

    • Author(s)
      Nakazawa Y, Sato S, Naito M, Kato Y, Mishima K, Arai H, Tsuruo T, Fujita N.
    • Journal Title

      Blood 112

      Pages: 1730-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] TUSC4/NPRL2, a novel PDK1-interacting protein, inhibits PDK1 tyrosine phosphorylation and its downstream signaling2008

    • Author(s)
      Kurata A, Katayama R, Watanabe T, Tsuruo T, Fujita N.
    • Journal Title

      Cancer Sci. 99

      Pages: 1827-34

    • NAID

      10024011166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Telomere elongation by a mutant tankyrase 1 without TRF1 poly(ADP-ribosyl)ation2008

    • Author(s)
      Muramatsu Y, Tahara H, Ono T, Tsuruo T, Seimiya H.
    • Journal Title

      Exp Cell Res. 314

      Pages: 1115-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Platelet aggregation in the formation of tumor metastasis2008

    • Author(s)
      Tsuruo T, Fujita N.
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci. 84

      Pages: 189-98

    • NAID

      130000093935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Freud-1/Aki1, a novel PDK1-interacting protein, functions as a scaffold to activate the PDK1/Akt pathway in epidermal growth factor signaling2008

    • Author(s)
      Nakamura A, Naito M, Tsuruo T, Fujita N.
    • Journal Title

      Mol Cell Biol.

      Pages: 5996-6009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] FOXO transcription factor-dependent p15(INK4b) and p19(INK4d) expression2008

    • Author(s)
      Katayama K, Nakamura A, Sugimoto Y, Tsuruo T, Fujita N.
    • Journal Title

      Oncogene 27

      Pages: 1677-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Impairment of the ubiquitin-proteasome system by cellular FLIP2007

    • Author(s)
      Ishioka T, Katayama R, Kikuchi R, Nishimoto M, Takada S, Takada R, Matsuzawa S, Reed JC, Tsuruo T, Naito M.
    • Journal Title

      Genes Cells. 12

      Pages: 735-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] The platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasis2007

    • Author(s)
      Kunita A, Kashima TG, Morishita Y, Fukayama M, Kato Y, Tsuruo T, Fujita N.
    • Journal Title

      Am J Pathol. 170

      Pages: 1337-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation2007

    • Author(s)
      Tsukumo Y, Tomida A, Kitahara O, Nakamura Y, Asada S, Mori K, Tsuruo T.
    • Journal Title

      J Biol Chem 282

      Pages: 29264-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo2007

    • Author(s)
      Tokuda E, Fujita N, Oh-hara T, Sato S, Kurata A, Katayama R, Itoh T, Takenawa T, Miyazono K, Tsuruo T.
    • Journal Title

      Cancer Res. 67

      Pages: 9666-76

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracilfor patients with advanced or recurrent breast cancer.2007

    • Author(s)
      Saeki, T., Tsuruo, T., et al.
    • Journal Title

      J Clin Oncol. 25 (4)

      Pages: 411-417

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] Evaluation of tankyrase inhibition in whole cells2007

    • Author(s)
      Ohishi T, Tsuruo T, Seimiya H.
    • Journal Title

      Methods Mol Biol. 405

      Pages: 133-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Dofequidar fumarate (MS-209) in combination with cyclophosphamide, doxorubicin, and fluorouracil for patients with advanced or recurrent breast cancer2007

    • Author(s)
      Saeki T, Nomizu T, Toi M, Ito Y, Noguchi S, Kobayashi T, Asaga T, Minami H, Yamamoto N, Aogi K, Ikeda T, Ohashi Y, Sato W, Tsuruo T.
    • Journal Title

      J Clin Oncol. 25

      Pages: 411-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] 3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling2005

    • Author(s)
      Tanaka H, Fujita N, Tsuruo T.
    • Journal Title

      J Biol Chem. 280

      Pages: 40965-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Tankyrase 1 as a target for telomere-directed molecular cancer therapeutics2005

    • Author(s)
      Seimiya H, Muramatsu Y, Ohishi T, Tsuruo T.
    • Journal Title

      Cancer Cell. 7

      Pages: 25-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Defects of the apoptotic pathway as therapeutic target against cancer2005

    • Author(s)
      Mashima T, Tsuruo T.
    • Journal Title

      Drug Resist Updat. 8

      Pages: 339-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Stabilization of integrin-linked kinase by binding to Hsp902005

    • Author(s)
      Aoyagi Y, Fujita N, Tsuruo T.
    • Journal Title

      Biochem Biophys Res Commun 331(4)

      Pages: 1061-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Tankyrase I as a target for telomere-directed molecular cancer therapeutics.2005

    • Author(s)
      Seimiya, H., Tsuruo, T.et al.
    • Journal Title

      Cancer Cell. 7

      Pages: 25-37

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target2005

    • Author(s)
      Mashima T, Oh-hara T, Sato S, Mochizuki M, Sugimoto Y, Yamazaki K, Hamada J, Tada M, Moriuchi T, Ishikawa Y, Kato Y, Tomoda H, Yamori T, Tsuruo T.
    • Journal Title

      J Natl Cancer Inst. 97

      Pages: 765-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016012
  • [Journal Article] Molecular targeting therapy of cancer : drug resistance apoptosis and survival signal.2003

    • Author(s)
      Tsuruo, T.
    • Journal Title

      Cancer Sci 94

      Pages: 15-21

    • NAID

      10016247833

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11177101
  • [Journal Article] Molecular targeting therapy of cancer : drug resistance apoptosis and survival signal.2003

    • Author(s)
      Tsuruo, T., et al.
    • Journal Title

      Cancer Sci 94

      Pages: 15-21

    • NAID

      10016247833

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11177101
  • [Presentation] ミトコンドリアはグルコース飢餓環境下のがん細胞の生存を制御する2009

    • Author(s)
      芳賀直実, 齋藤さかえ, 鶴尾隆, 築茂由則, 冨田章弘
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-17016012
  • 1.  塚越 茂 (60085644)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  稲葉 実 (60085636)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 3.  TANIGUCHI Tadatsugu (50133616)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  矢守 隆夫 (60200854)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  杉本 芳一 (10179161)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 6.  濱田 洋文 (00189614)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TAKAI Yoshimi (60093514)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  UEDA Ryuzo (20142169)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  SHIBUYA Masabumi (10107427)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  吉田 光昭 (80012607)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  内藤 幹彦 (00198011)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 12.  TOMIDA Akihiro (40251483)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 13.  田代 田鶴子 (20085608)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 14.  田代 田鶴子 (50085635)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 15.  IMAI Kohzoh (60117603)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  MUTO Tetsuichiro (20110695)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  安藤 俊夫 (20012693)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  筒井 研 (70108158)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  池田 日出男 (10012775)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  柳田 充弘 (80025428)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  上田 重晴 (90068453)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 23.  竹内 富雄 (30163380)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 24.  豊島 久真男 (90029760)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 25.  井村 裕夫 (10025570)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 26.  八巻 寛 (30013329)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 27.  白川 茂 (20026850)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 28.  曽根 三郎 (40145024)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 29.  玉置 憲一 (50055860)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 30.  下山 正徳 (50110002)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 31.  遊佐 敬介 (30200869)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 32.  大岳 望 (30013303)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 33.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 34.  ITO Yoshiaki (80004612)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 35.  KUROKI Toshio (90006073)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 36.  TSUKITA Shouichiro (50155347)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 37.  MASHIMA Tetsuo (30311228)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 38.  IWASAKI Shigeo (00013326)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 39.  KITAYAMA Joji (20251308)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 40.  NAGAWA Hirokazu (80228064)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 41.  NISHIMURA Toshio (10013327)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 42.  SAKUDA Shohei (80192087)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 43.  TAJIMA Kazuo (30150212)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 44.  KAWAI Sadaaki (70107423)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 45.  中島 元夫 (90240738)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 46.  濱岡 利之 (60028529)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 47.  小宮山 寛機 (00106676)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 48.  三上 襄 (40092100)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 49.  浦本 昌和 (00124363)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 50.  瀬戸 治男 (10013335)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 51.  姚 新生
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 52.  崔 承彬
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 53.  YAO Xin-sheng
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 54.  CUI Cheng-bin
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 55.  MIYAZONO Kohei (90209908)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  SAITO Izumu (70158913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  HASHIDA Mitsuru (20135594)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  ENDO Keigo (10115800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  ITOH Kyogo (50125499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  INAZAWA Johji (30193551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  HAGA Naomi (40376645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 62.  RYOUHEI Katayama (60435542)
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  • 138.  劭 剛
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