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ARIGA Hiroyoshi  有賀 寛芳

ORCIDConnect your ORCID iD *help
Researcher Number 20143505
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2013: 北海道大学, 薬学研究科(研究院), 教授
2007 – 2012: Hokkaido University, Gard. School of Pharma, Sci. Prof.
2007: Hokkaido University, 大学院・医学研究科, 教授
2006: Hokkaido Univ., Faculty of Pharmaceutical Sciences, Professor, 大学院薬学研究院, 教授
1998 – 2005: 北海道大学, 大学院・薬学研究科, 教授 … More
2002: 北海道大学, 大学院・医学研究科, 教授
1988 – 1997: 北海道大学, 薬学部, 教授
1995: HOKKAIDO UNIVERSITY,FACULTY OF PHARMACEUTICAL SCIENCES,PROFESSOR, 薬学部, 教授
1989: 北海道大学, 薬学部・微生物薬品化学, 教授
1988: 東京大学, 医科学研究所, 助教授
1988: 東京大学, 医科学研究所ウイルス学, 助手
1988: 東京大学, 医科研 ウイルス研究部, 助手
1986 – 1988: 東京大学, 医科学研究所, 助手
1987: 東京大学, 医科学研究所・ウィルス学, 助手
1986: 東大, 医科学研究所, 助手
1986: 東大, 医科研・ウイルス研究部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological Sciences / Biological pharmacy / Environmental pharmacy / Biological Sciences / Urology / Ophthalmology / Science and Engineering
Except Principal Investigator
Biological Sciences / Biological pharmacy … More / Neurology / Laboratory medicine / 分子遺伝学・分子生理学 / Biological pharmacy / Ophthalmology / 植物生理 / Virology Less
Keywords
Principal Investigator
c-myc / DNA複製 / 癌遺伝子 / DJ-1 / N-myc / ミトコンドリア / パーキンソン病 / 転写因子 / 細胞周期 / 酸化ストレス … More / 活性酸素 / 精子形成 / 転写制御 / hsp70 / アポトーシス / c-Myc / MYC / 神経変性疾患治療薬 / チロシンヒドロキシラーゼ / Pim-1 / 転写調節 / 癌抑制遺伝子 / DNA replication / エンハンサー / プロテアーゼ / タンパク質分解 / SUMO-1 / 内分泌かく乱物質 / アンドロゲン受容体 / BIG2 / AMY-1 / MM-1 / tumor suppressor / oncogene / co-repressor / クロマチン / リン酸化 / apoptosis / cell cycle / 転写 / DNA結合 / 結合タンパク質 / 発現ベクター / p53 / DNA複製開始 / SV40 / 熱ショックタンパク / 転写促進活性 / 遺伝子 / 蛋白質 / ストレス / 癌 / 脳神経疾患 / 創薬 / DJ-1結合化合物 / チロシン水酸化酵素 / 複合体I / ドパミン / ゲノム / 神経変性疾患 / プロテオーム / 遺伝学 / 神経科学 / 受精 / DNA断片化 / DNA結合タンパク質 / 神経細胞 / HSP70 / neurodegeneration disease / reactive oxygen species / tyrosine hydroxylase / mitochondria / oxidative stres / Parkinson's disease / ubiquitin / Golgi apparatu / protein degradatin / PKA / c-fms / AKAP / ユビキチン / ゴルジ体 / spermatogenesis / embryonic lethal / transcription factor / transformation / 胎生致死 / コリプレッサー / 発ガン / chromatin / phosphorylation / transcrition / tumor suppresser / PRC1 / ORC1 / transcroption / cell transformation / cDNAクローニング / 細胞癌化 / transcription / heat shock protein / vector / adenovirus / ベクター / アデノウイルス / CELL CYCLE / TRANSFORMATION / APOPTOSIS / TRANSCRIPTION FACTOR / DNA BINDING / C-MYC / MHC classI / トランスフォーメーション / 癌化 / Expression vector / Gene therapy / Immunoglobulin / Hcp70 / DNA replication origin / トランスジェニックマウス / 自律増殖配列 / 形質発現ベクター / 免疫グロブリンH鎖 / Alu family / immunoglobulin / transcriptional regulation / 複製開始 / Alu配列 / 免疫グロブリン / myc遺伝子 / Aluファミリー / AIuファミリー / イムノグロブリン / DNA結合タンパク / リプレッサー / ori / C-mycタンパク / 熱ショックタンパク遺伝子 / Cーmycタンパク / SV40T抗原 / C-myc蛋白 / T抗原 / パポーバウィルス / 活性酵素 / チロシンヒデロキシラーゼ / CIR / Prp3 / スプライソソーム / 網膜細胞死 / スプライシング / 網膜性色素変性症 / PAP-1 / 神経細胞死 / パーキンソン氏病 / 内分泌攪乱物質 / AR / 不妊 / MSSP / NS-1 / 細胞死 / Nーmyc / cーmyc … More
Except Principal Investigator
c-Myc / 癌抑制遺伝子 / AMY-1 / C-MYC / MSSP / 転写調節 / MM-1 / 癌遺伝子 / タンパク質分解 / DNAポリメラーゼ / アデノウイルス / DNA複製 / DJ-1 / エンハンサー / DNA合成酵素の遺伝子 / ARS / ミトコンドリア / 酸化ストレス / パーキンソン病 / Pim-1 / RP9 / PAP-1 / ORC1 / トポイソメラーゼ / HTLV-1 / プロテアソーム / ユビキチン / リンパ腫 / リン酸化 / 細胞周期 / c-myc / RBタンパク / HBVXタンパク / 発現調節領域 / DNA腫瘍ウイルス / 核内癌遺伝子産物 / German-Japanese collaborative program in cancer research / French-Japanese collaborative programe in cancer research / Growth Factors / Cytokines / Tumor Suppressor Genes / Oncogenes / Human Gene Mapping / International Exchange Program / 増殖因子 / サイトカイン / 発がん / DNA修復 / ヒトがん遺伝子 / ヒトレトロウイルス / がん抑制遺伝子 / がん遺伝子 / Qa gene / novel HLA class I gene / 主要組織適合抗原 / HLAC-Blank遺伝子 / HLA抗原 / Qa遺伝子 / HLA-C blank遺伝子 / 新しいHLAクラスI遺伝子 / transcription / autoregulation / RAN-DNA transition site / origin sequence / initiator protein / ori DNA / Rep蛋白 / 複製開始機構 / プラスミド / 自己制御 / oriDNA / 繰返し配列 / イニシエーター蛋白(Rep蛋白) / neurodegeneration disease / oncogene / reactive oxygen species / tyrosine hydroxylase / mitochondria / oxidative stress / Parkinson's disease / 神経変性疾患治療薬 / 活性酸素 / チロシンヒドロキシラーゼ / cell adhesion activity / collagen fibrillogenesis / serum form / tenascin-X / extracellular matrix / 脂肪酸 / 癌 / 接着活性 / コラーゲン線維形成 / 血清型 / テネイシン / 細胞外マトリックス / genome / neurodegenerative disease / proteome / Genomics / Neuroscience / プロテアーゼ / SUMO-1 / 神細細胞死 / ゲノム / 神経変性疾患 / プロテオーム / 遺伝学 / 神経科学 / retina / phosphorylation / splicing / retinitis pigmentosa / c-MYc / 網膜 / スプライシング / 網膜性色素変性症 / tumor suppressor / spermatogenesis / transcriptional regulation / トランスフォーメイション / 癌抑制因子 / 精子形成 / DNA BINDING PROTEINS / YEAST / CELL CYCLE / TRANSCRIPTION / REPLICATION / 核移行阻止 / DNAポリメラーゼα / DNA結合タンパク / 酵母 / 転写 / 複製 / Kidney bean leaves / Jasmonic acid / Environmental stresses / Linolenic-acid metabolism / Galactolipids / Galactolipase / インゲン葉 / 環境ストレス / ジャスモン酸 / リノレン酸代謝 / ガラクト脂質 / ガラクトリパーゼ / Receptor / Endothelial cells / Host defense / Anaphylatoxin / Immunology / Complement / レセプター / 血管内皮細胞 / 生体防御 / アナフィラトキシン / 免疫 / 補体 / RNAレプリコン / 研究支援組織 / 教育体制 / プロジェクト / 研究費 / 研究推進 / ウイルス / トランスジェニックマウス / DNA合成開始点 / cDNAライブラリーmyc / 網膜芽細胞腫 / 遺伝子発現 / T抗原 / c-mycタンパク質 / 複製開始点 / 転写と複製の相関 / 発現抑制領域 / HPV / BKV / DNA複制開始点 / cーmycタンパク質 / 転写調節因子 / myc産物 / BKウイルス / コレプレッサー / c-fms / 癌化 / コリプレッサー / 転写因子 / 発ガン / クロマチン / 転写制御 / co-repressor / トポイソメラ-ゼ / DNAヘリカ-ゼ / プライマ-ゼ / DNAポリメラ-ゼ / SV40ミニクロモソ-ム / パピロ-マウイルス / ポリオ-マウイルス / DNAアフィニティカラム / ヌクレオソ-ム / 2 / CDC28 / 自律増殖配列 / cーmycタンパク / 試験管内DNA複製系 / C-Mycタンパク質 / c-Fosタンパク質 / 細胞増殖と分化 / サイレンサー / 遺伝子発現調節 / パピローマウイルス / ポリオーマウイルス Less
  • Research Projects

    (57 results)
  • Research Products

    (83 results)
  • Co-Researchers

    (77 People)
  •  DJ-1によるドレブリンを介したスパイン形成調節Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  家族性パーキンソン病PARK7原因遺伝子DJ-1の機能解析と創薬Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Functional analysis of DJ-1, a causative gene for familial Parkinson's disease, and its pharmaceutical applicationPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  パーキンソン病PARK7の原因遺伝子DJ-1の機能解析Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  パーキンソン病PARK7の原因遺伝子DJ-1の機能解析Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  内分泌かく乱物質による精子形成不全と協調するタンパク質DJ-1Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Hokkaido University
  •  Function of DJ-1, a causative gene for familial Parkinson's disease PARK7 and oncogenePrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Function of DJ-1, a causative gene for familial Parkinson's disease PARK7

    • Principal Investigator
      ARIGA Sanae
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Hokkaido University
  •  パーキンソン病PARK7の原因遺伝子DJ-1の機能解析Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  Functional Analysis of extracellular matrix tenascin-X

    • Principal Investigator
      MATSUMOTO Ken-ichi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  パーキンソン病PARK7の原因遺伝子DJ-1の構造と機能Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  網膜性色素変性症RP9の原因遺伝子PAP-1の機能と診断マーカー,治療薬の確立Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Hokkaido University
  •  Function of DJ-1, a causative gene for familial Parkinson's disease PARK7

    • Principal Investigator
      ARIGA Sanae
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能

    • Principal Investigator
      有賀 早苗
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能

    • Principal Investigator
      有賀 早苗
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  内分泌攪乱物質のターゲットタンパク質DJ-1の機能解析Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      Hokkaido University
  •  Function of PAP-1,a causative gene for retinitis pigmentosa

    • Principal Investigator
      ARIGA Sanae
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Functions of Myc and c-Myc-binding proteinsPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  新規C-Myc結合タンパク質MM-1がん抑制遺伝子産物としての機能

    • Principal Investigator
      有賀 早苗
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  内分泌かく乱物質による精子形成不全と協調するタンパク質DJ-1-男性抗不妊薬,不妊マーカーの可能性-Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hokkaido University
  •  新規c-Myc結合タンパク質MM-1のがん抑制遺伝子産物としての機能

    • Principal Investigator
      有賀 早苗
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
  •  内分泌かく乱物質による精子形成不安と協調するタンパク質DJ-1-男性抗不妊薬,不妊マーカーの可能性-Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hokkaido University
  •  Regulation of cell-cycle movement and cell transformation by c-Myc and its binding proteinsPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  化学発癌剤等による精子形成不全と協調するタンパク質DJ-1-男性抗不妊薬の可能性-Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Environmental pharmacy
    • Research Institution
      Hokkaido University
  •  Mechanism of Functional Switching of C-MYC: Formation of Different Protein Complexes and Expression of Activities in DNA Replication, Transcription and Apoptosis Induction during the Cell Cycle.

    • Principal Investigator
      ARIGA Sanae
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Regulation of cell-cycle movement and cell transformation by nuclear oncogenes.Principal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Molecular mechanism of cell proliferation and appoptosis by the actions of transcription/replication factors in mammalian cells.Principal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  MOLECULAR MECHANISMS OF THE CELL CYCLE REGULATION BY REPLICATION/TRANSCRIPTION FACTORS,MSSP

    • Principal Investigator
      ARIGA Sanae
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Establishment of gene therapy vector by using DNA replication origin and virus vectorPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  神経細胞死とmycPrincipal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  Conservative regulation of DNA replication and transcription in mammalian cellsPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  A biochemical role of galactolipase in the metabolic pathway of linolenic acid in higher plants.

    • Principal Investigator
      SAKAKI Takeshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      植物生理
    • Research Institution
      HOKKAIDO TOKAI UNIVERSITY
  •  神経細胞の増殖.分化に関与するmyc遺伝子とアポトーシス、神経難病Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  ヒト熱ショックタンパク質70(HSP70)遺伝子の発現調節と産物タンパク質の機能Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  神経細胞の増殖・分化に関与するmyc遺伝子と神経難病Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Hokkaido University
  •  Studies on molecular constitution and effector functions of complement system

    • Principal Investigator
      NAGASAWA Shigeharu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  Construction of expression vectors using initiation sites of DNA replication and their application to gene therapyPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  DNA複製反応の促進及び抑制のメカニズムと癌化

    • Principal Investigator
      吉田 松年
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  Concerted mechanism of DNA replication initiation and transcription in mammalian cellsPrincipal Investigator

    • Principal Investigator
      ARIGA Hiroyoshi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Hokkaido University
  •  DNA複製反応の促進及び抑制のメカニズムと癌化

    • Principal Investigator
      吉田 松年
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Nagoya University
  •  ウイルス癌遺伝子産物による細胞およびウイルスDNA複製の調節

    • Principal Investigator
      吉池 邦人
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      国立予防衛生研究所
  •  細胞性癌遺伝子mycタンパク質の機能と細胞内情報伝達系における役割Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Hokkaido University
  •  ウイルス癌遺伝子産物による細胞およびウイルスDNA複製の調節

    • Principal Investigator
      吉池 邦人
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      国立予防衛生研究所
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  癌遺伝子の転写と複製の調節

    • Principal Investigator
      吉池 邦人
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      国立予防衛生研究所
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  SV40 T抗原による細胞遺伝子発現の変化

    • Principal Investigator
      菅野 純夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ウイルス研究推進のための調査研究

    • Principal Investigator
      石浜 明
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Virology
    • Research Institution
      National Institute of Genetics
  •  DNA複製開始部位とでDNA複製タンパクの相互作用Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  DNA合成酵素遺伝子の構造と機能

    • Principal Investigator
      松影 昭夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Aichi Cancer Center Research Institute
  •  パポーバウィルス発がん遺伝子産物と細胞内因子との相互作用Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  DNA複製開始部位とDNA複製タンパクとの相互作用Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  癌遺伝子の転写と複製の調節

    • Principal Investigator
      吉池 邦人
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      国立予防衛生研究所
  •  The study of novel HLA class I gene

    • Principal Investigator
      TAKIGUCHI Masafumi M.D.
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      The University of Tokyo
  •  パポーバウイルス発がん遺伝子産物と細胞内因子との相互作用Principal Investigator

    • Principal Investigator
      有賀 寛芳
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  Molecular mechanism of initiation of DNA replication

    • Principal Investigator
      OKAZAKI Tuneko
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Nagoya University

All 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

  • [Book] 別冊・医学のあゆみ「ここまでわかったミトコンドリア研究の新展開」2011

    • Author(s)
      有賀寛芳
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Book] ここまでわかったミトコンドリア研究の新展開2011

    • Author(s)
      有賀寛芳(共著)
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Book] 酸化ストレス防御系の破綻とパーキンソン病、別冊・医学のあゆみ「ここまでわかったミトコンドリア研究の新展開」2011

    • Author(s)
      有賀寛芳、有賀早苗
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Book] ここまでわかったパーキンソン病研究-抗酸化ストレス因子としてのPark7/DJ-1とパーキンソン病2009

    • Author(s)
      有賀寛芳、有賀早苗
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Book] 別冊・医学のあゆみ「ここまでわかったパーキンソン病研究」抗酸化ストレス因子としてのPark7/DJ-1とパーキンソン病2009

    • Author(s)
      有賀寛芳、有賀早苗
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Book] ここまでわかったパーキンソン病研究2009

    • Author(s)
      有賀寛芳
    • Total Pages
      110
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20023003
  • [Book] ここまでわかったパーキンソン病研究-抗酸化ストレス因子としてのPark7/DJ-1とパーキンソン病2009

    • Author(s)
      有賀寛芳、有賀早苗
    • Total Pages
      5
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-20023003
  • [Book] クラーク 分子生物学2008

    • Author(s)
      有賀寛芳
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Book] クラーク 分子生物学2008

    • Author(s)
      有賀寛芳
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-18659467
  • [Book] クラーク 分子生物学2008

    • Author(s)
      有賀寛芳
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-18023002
  • [Book] クラーク 分子生物学2008

    • Author(s)
      有賀寛芳
    • Publisher
      丸善
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390253
  • [Book] 別冊・医学のあゆみ,「パーキンソン病」-最新動向2005

    • Author(s)
      有賀寛芳, 有賀早苗, 平 敬宏
    • Total Pages
      150
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-17025001
  • [Book] 別冊・医学のあゆみ,「パーキンソン病」 最新動向2005

    • Author(s)
      有賀寛芳, 有賀早苗, 平 敬宏
    • Total Pages
      150
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-16390248
  • [Book] 別冊・医学のあゆみ,「パーキンソン病」・最新動向2005

    • Author(s)
      有賀寛芳, 有賀早苗, 平 敬宏
    • Total Pages
      150
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-16659469
  • [Book] 別冊・医学のあゆみ,「パーキンソン病」-最新動向2005

    • Author(s)
      有賀寛芳, 有賀早苗, 平 敬宏
    • Total Pages
      150
    • Publisher
      医歯薬出版
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390248
  • [Journal Article] CHFR regulates the mitotic checkpoint by targeting PARP-1 for ubiquitination and degradation2012

    • Author(s)
      Kashima, L., Idogawa, M., Mita, H., Shitashige, M., Yamada, T., Ogi, K., Suzuki, H., Toyota, M., Ariga, H., Sasaki, Y., Tokino, T.
    • Journal Title

      J. Biol. Chem

      Volume: 287 Issue: 16 Pages: 12975-12984

    • DOI

      10.1074/jbc.m111.321828

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790654, KAKENHI-PROJECT-22791293, KAKENHI-PROJECT-23390469, KAKENHI-PROJECT-23590376, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658
  • [Journal Article] Transcriptional activation of low-density lipoprotein receptor gene by DJ-1 and effect of DJ-1 on cholesterol homeostasis2012

    • Author(s)
      Yamaguchi, S., Yamane, T., Takahashi-Niki, K., Kato, I., Niki, T., Goldberg, M. S., Shen, J., Ishimoto, K., Doi, T., Iguchi-Ariga, S. M. M., Ariga, H.
    • Journal Title

      PLoS ONE

      Volume: 7 Issue: 5 Pages: e38144-e38144

    • DOI

      10.1371/journal.pone.0038144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22300119, KAKENHI-PROJECT-23790087, KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-24390013, KAKENHI-PROJECT-24650191, KAKENHI-PUBLICLY-23117502
  • [Journal Article] Stimulation of vesicular monoamine transporter 2 activity by DJ-1 in SH-SY5Y cells2012

    • Author(s)
      Ishikawa, S., Tanaka, Y., Takahashi-Niki, K., Niki, T., Ariga, H., Iguchi-Ariga, S. M. M.
    • Journal Title

      Biochem. Biophys. Res. Commun

      Volume: 42 Issue: 4 Pages: 813-818

    • DOI

      10.1016/j.bbrc.2012.04.095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22300119, KAKENHI-PROJECT-23790970, KAKENHI-PROJECT-24650191, KAKENHI-PUBLICLY-23117502
  • [Journal Article] Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits2011

    • Author(s)
      Miyazawa, M., Tashiro, E., Kitaura, H., Maita, H., Suto, H., Iguchi-Ariga, S. M. M., Ariga, H.
    • Journal Title

      J. Biol. Chem

      Volume: 286 Issue: 22 Pages: 1919-19203

    • DOI

      10.1074/jbc.m110.216259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] DJ-1-mediated Protective Effect of Protocatechuic Aldehyde against Oxidative Stress in SH-SY5Y cells2011

    • Author(s)
      Gao, J-W., Yamane, T., Maita, H., Ishikawa, S., Iguchi-Ariga, S. M. M., Pu, X-P., Ariga, H.
    • Journal Title

      J. Pharmacol. Sci

      Volume: 115 Pages: 36-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Identification and characterization of an oocyte factor required for development of porcine nuclear transfer embryos2011

    • Author(s)
      Miyamoto, K., Nagai, K., Kitamura, N., Nishikawa, T., Ikegami, H., Binh, N., Tsukamoto, S., Matsumoto, M., Tsukiyama, T., Minami, N., Yamada, M., Ariga, H., Miyake, M., Kawarasaki, T., Matsumoto, K., Imai, H.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 108 Issue: 17 Pages: 7040-7045

    • DOI

      10.1073/pnas.1013634108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22380150, KAKENHI-PROJECT-23380164, KAKENHI-PROJECT-23658292
  • [Journal Article] A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 12011

    • Author(s)
      Kagawa, H., Shino, Y., Kobayashi, D., Demizu, S., Shimada, M., Ariga, H., Kawahara, H.
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 51 Pages: 39718-39731

    • DOI

      10.1074/jbc.m110.137034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790809
  • [Journal Article] DJ-1 associates with synaptic membranes2011

    • Author(s)
      Yukiko Usami, Taku Hatano, Satoshi Imai, Shin-ichiro Kubo, Shigeto Sato, Shinji Saiki, Yoichiro Fujioka, Yusuke Ohba, Fumiaki Sato, Manabu Funayama. Hiroto Eguchi, Kaori Shiba, Hiroyoshi Ariga, Jie Shen, Nobutaka Hattori
    • Journal Title

      Neurobiology of Disease

      Volume: 43 Issue: 3 Pages: 651-662

    • DOI

      10.1016/j.nbd.2011.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J04616, KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22790829, KAKENHI-PUBLICLY-23114501, KAKENHI-PUBLICLY-23129506, KAKENHI-PROJECT-23390090, KAKENHI-PROJECT-23659196, KAKENHI-PROJECT-23700389
  • [Journal Article] Protection Against Dopaminergic Neurodegeneration in Parkinson's Disease-Model Animals by a Modulator of the Oxidized Form of DJ-1, a Wild-type of Familial Parkinson's Disease-Linked PARK72011

    • Author(s)
      Inden, M., Kitamura, M., Takahashi, K., Takata, K., Ito, N., Niwa, R., Funayama, R., Nishimura, K., Taniguchi, T., Honda, T., Taira, T., Ariga, H.
    • Journal Title

      J Pharmacol Sci

      Volume: 117 Issue: 3 Pages: 189-203

    • DOI

      10.1254/jphs.11151FP

    • NAID

      10030453398

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-21590091
  • [Journal Article] Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats2011

    • Author(s)
      Kitamura, Y., Watanabe, S., Taguchi, M., Takagi, K., Kawata, T., Takahashi-Niki, K., Yasui, H., Maita, H., Iguchi-Ariga, S. M. M., Ariga, H.
    • Journal Title

      Mol. Neurodegeneration

      Volume: 6 Issue: 1 Pages: 48-48

    • DOI

      10.1186/1750-1326-6-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014, KAKENHI-PROJECT-22300119, KAKENHI-PUBLICLY-23117502, KAKENHI-PROJECT-23790970
  • [Journal Article] DJ-1, an oncogene and causative gene for familial Parkinson's disease, is essential for SV40 transformation in mouse fibroblasts through up-regulation of c-Myc2010

    • Author(s)
      Kim Y. C., Kitaura, H., Iguchi-Ariga, S. M. M., Ariga, H.
    • Journal Title

      FEBS Lett

      Volume: 584 Issue: 18 Pages: 3891-3895

    • DOI

      10.1016/j.febslet.2010.08.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Oxidation of DJ-1-dependent cell transformation through direct binding of DJ-1 to PTEN. Int2009

    • Author(s)
      Kim, Y.-C., Kitaura, H., Taira, T., Iguchi-Ariga, S. M. M., Ariga, H.
    • Journal Title

      J. Oncol

      Volume: 35 Issue: 06 Pages: 1331-1341

    • DOI

      10.3892/ijo_00000451

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Recombinant human DJ-1 protein has a protective effect for dopaminergic neurons2009

    • Author(s)
      Kitamura, Y., Yanagida, T., Takata, K., Taniguchi, T., Ariga, H.
    • Journal Title

      Current Topics in Peptide & Protein Research

      Volume: 9 Pages: 47-55

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury. Oxid. Med2009

    • Author(s)
      Yanagida, T., Tsushima, J., Kitamura, Y., Yanagisawa, D., Takata, K., Shibaike, T., Yamamoto, A., Taniguchi, T., Yasui, H., Taira, T., Morikawa, S., Inubushi, T., Tooyama, I., Ariga, H.
    • Journal Title

      Cell. Long

      Volume: 1 Pages: 36-42

    • URL

      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763229/?tool=pubmed

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Protection Against Oxidative Stress-Induced Neurodegeneration by a Modulator for DJ-1, the Wild-Type of Familial Parkinson's Disease-Linked PARK72009

    • Author(s)
      Yanagida, T., Kitamura, Y., Yamane, K., Takahashi, K., Takata, K., Yanagisawa, D., Yasui, H., Taniguchi, T., Taira, T., Honda, T., Ariga, H.
    • Journal Title

      J Pharmacol Sci

      Volume: 109 Issue: 3 Pages: 463-468

    • DOI

      10.1254/jphs.08323SC

    • NAID

      130000106980

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's dsease-lnked PARK7. Int2009

    • Author(s)
      Yamane, K., Kitamura, Y., Yanagida, T., Takata, T., Yanagisawa, D., Taniguchi, T., Taira, T., Ariga, H.
    • Journal Title

      J. Mol. Sci

      Volume: 10 Issue: 11 Pages: 4789-4804

    • DOI

      10.3390/ijms10114789

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Oxidative status of DJ-1-dependent activation of dopamine synthesis through interaction of tyrosine hydroxylase and 4-dihydroxy-l-phenylalanine (l-DOPA) decarboxylase with DJ-12009

    • Author(s)
      Ishikawa, S., Taira, T., Niki, T., Takahashi-Niki, K., Maita, C., Maita, H., Ariga, H., Iguchi-Ariga, S. M. M.
    • Journal Title

      J. Biol. Chem

      Volume: 284 Issue: 42 Pages: 28832-28844

    • DOI

      10.1074/jbc.m109.019950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice2009

    • Author(s)
      Inden, M., Kitamura, Y., Tamaki, A., Yanagida, T., Shibaike, T., Yamamoto, A., Takata, K., Yasui, H., Taira, T., Ariga, H., Taniguchi, T.
    • Journal Title

      Neurochem. Int

      Volume: 55 Issue: 8 Pages: 760-767

    • DOI

      10.1016/j.neuint.2009.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Kaempferol Derivatives Prevent Oxidative Stress-Induced Cell Death in a DJ-1-Dependent Manner2009

    • Author(s)
      Qu, W., Fan, L., Kim, Y.-C., Ishikawa, S., Iguchi-Ariga, S. M. M., Pu, X.-P., Ariga, H.
    • Journal Title

      J Pharmacol Sci

      Volume: 110 Issue: 2 Pages: 191-200

    • DOI

      10.1254/jphs.09045FP

    • NAID

      10025737178

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] PAPA-1 is a nuclear binding partner of IGFBP-2 and modulates its growth promoting actions2009

    • Author(s)
      Miyako, K., Cobb, L. J., Francis, M., Huang, A., Peng, B., Pintar, J. E., Ariga, H., Cohen, P.
    • Journal Title

      Mol. Endocrinol

      Volume: 23 Issue: 2 Pages: 169-175

    • DOI

      10.1210/me.2008-0168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] DJ-1 binds to mitochondrial complex I and maintains its activity2009

    • Author(s)
      Hayashi, T., Ishimori, C., Takahashi-Niki, K., Taira, T., Kim, Y-C., Maita, H., Maita, C., Ariga, H.,
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 390 Pages: 667-672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Journal Article] Distinct glycosylation in interstitial and serum tenascin-X.2007

    • Author(s)
      Takeshi Kinoshita, Hiroyoshi Ariga, Ken-ichi Matsumoto.
    • Journal Title

      Biol.Pharm.Bull. 30

      Pages: 354-358

    • NAID

      110006162857

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590048
  • [Journal Article] Characterization of serum tenascin-X in mice.2006

    • Author(s)
      Ken-ichi Matsumoto, Takeshi Kinoshita, Tomohiro Hirose, Hiroyoshi Ariga.
    • Journal Title

      DNA and Cell Biol. 25

      Pages: 448-456

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590048
  • [Journal Article] Parkinson's disease - recent topics2005

    • Author(s)
      Ariga et al.
    • Journal Title

      Igakuno Ayumi

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390248
  • [Journal Article] Transcription regulatory complex including YB-1 controls expression of mouse matrix metalloproteinase-2 Gene in NIH3T3 cells.2005

    • Author(s)
      Ken-ichi Matsumoto, Shun Abiko, Hiroyoshi Ariga.
    • Journal Title

      Biol.Pharm.Bull. 28

      Pages: 1500-1504

    • NAID

      120005350118

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590048
  • [Journal Article] Positive regulation of Fas gene expression by MSSP and abrogation of Fas- mediated apoptosis induction in MSSP-deficient mice.2005

    • Author(s)
      Jun Nomura, Ken-ichi Matsumoto, Sanae M.M.Iguchi-Ariga, Hiroyoshi Ariga.
    • Journal Title

      Exp.Cell Res. 305

      Pages: 324-332

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590048
  • [Patent] 特許2012

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2012-11-20
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24390013
  • [Patent] 神経変性疾患治療薬2011

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2011-03-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Patent] 神経変性疾患治療薬2011

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      有賀寛芳
    • Filing Date
      2011-03-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Patent] 神経変性疾患治療薬2010

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      有賀寛芳
    • Industrial Property Number
      2010-072820
    • Filing Date
      2010-03-26
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Patent] パーキンソン病治療薬としての生薬由来化合物2010

    • Inventor(s)
      蒲小平、有賀寛芳、高建偉
    • Industrial Property Rights Holder
      蒲小平、有賀寛芳、高建偉
    • Filing Date
      2010-10-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Patent] パーキンソン病治療薬としての生薬由来化合物2008

    • Inventor(s)
      蒲小平、有賀寛芳、曲偉、果徳安
    • Industrial Property Rights Holder
      蒲小平、有賀寛芳
    • Filing Date
      2008-12-23
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20023003
  • [Patent] 神経変性疾患治療薬2006

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2006-11-28
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Patent] 神経変性疾患治療薬2006

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2006-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Patent] 神経変性疾患治療薬2006

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2006-11-28
    • Data Source
      KAKENHI-PROJECT-18023002
  • [Patent] 神経変性疾患治療薬2006

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2006-11-28
    • Description
      「研究成果報告書概要(和文)」より
    • Overseas
    • Data Source
      KAKENHI-PROJECT-18390253
  • [Patent] 神経変性疾患治療薬2006

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Filing Date
      2006-11-28
    • Data Source
      KAKENHI-PROJECT-18659467
  • [Patent] 神経変性疾患治療薬2005

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2005-339011
    • Filing Date
      2005-11-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390248
  • [Patent] 神経変性疾患治療薬2005

    • Inventor(s)
      有賀寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2005-339011
    • Filing Date
      2005-11-24
    • Data Source
      KAKENHI-PROJECT-16659469
  • [Patent] 神経変性疾患治療薬2005

    • Inventor(s)
      有賀 寛芳
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2005-339011
    • Filing Date
      2005-11-24
    • Data Source
      KAKENHI-PROJECT-17025001
  • [Presentation] Function of DJ-1 and its therapeutic application to Parkinson' S disease2012

    • Author(s)
      Ariga H.
    • Organizer
      The BRC International Conference 2012
    • Place of Presentation
      ShineVille Luxury Resort (Korea)
    • Year and Date
      2012-06-27
    • Data Source
      KAKENHI-PROJECT-24390013
  • [Presentation] Prefoldin protects neuronal cells from polyglutamine toxicity by preventing aggregation at small oligomer state2011

    • Author(s)
      Tashiro, E, Muto, H., Zako, T., Miyazawa, M., Kitaura, H., Kitamura, A., Kubota, H., Kinjo, M., Ariga, H.
    • Organizer
      The 41th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Washington Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] DJ-1 oxidized at C106 inhibits p53-activated DUSP1 expression by sequestering p53 from the promoter through binding to the DNA-binding region of p532011

    • Author(s)
      Kato, I., Maita, H., Takahashi-Niki, K, Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      The 41th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Washington Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] DJ-1のミトコンドリアにおける機能2011

    • Author(s)
      仁木(高橋)加寿子、仁木剛史、米田千夏、我那覇洋子、有賀(井口)早苗、有賀寛芳
    • Organizer
      日本薬学会第132年会シンポジウム
    • Place of Presentation
      北海道大学(札幌市)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Oxidative stress-response by DJ-1 and its binding compounds2011

    • Author(s)
      Niki, T., Takahashi-Niki, K., Okamoto, A., Endo, J., Ariga, H., Iguchi-Ariga, S. M. M.
    • Organizer
      The 41th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Washington Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Function of DJ-1 and its therapeutic application to Parkinson's disease2011

    • Author(s)
      Ariga, H., Kitamura, Y., Iguchi-Ariga, S. M. M.
    • Organizer
      AACL-2011 Japan-Korea Joint conference on brain aging and neurodegeneration
    • Place of Presentation
      長崎大学(長崎市)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] バーチャルスクリーニングによるパーキンソン病治療薬の開発2011

    • Author(s)
      有賀寛芳
    • Organizer
      第91回日本化学会シンポジウム
    • Place of Presentation
      神奈川大学(横浜市)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] DJ-1 oxidized at C106 inhibits p53-activated DUSP1 expression by sequestering p53 from the promoter2011

    • Author(s)
      Kato, I., Maita, H., Takahashi-Niki, K, Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      ISN-ESN 201123rd Biennial Meeting
    • Place of Presentation
      Athens Convention Center (Greece)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] バーチャルスクリーニングによるパーキンソン病治療薬の開発2011

    • Author(s)
      有賀寛芳
    • Organizer
      第91回日本化学会春秀年会シンポジウム
    • Place of Presentation
      横浜 招待講演
    • Year and Date
      2011-03-26
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Role of DJ-1 as an anti-oxidative stress sensor2011

    • Author(s)
      Niki, K, Niki, T., Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      ISN-ESN 201123rd Biennial Meeting
    • Place of Presentation
      Athens Convention Center (Greece)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Human DJ-1-specific transcriptional activation of the tyrosine hydroxylase gene2010

    • Author(s)
      Ishikawa, S., Taira, T., Niki-Takahashi, K., Niki, T., Ariga, H., Iguchi-Ariga, S. M. M.
    • Organizer
      The 40th annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Oxidative status of DJ-1-dependent regulation of the p53 signaling2010

    • Author(s)
      Kato, I., Maita, H., Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      The 40th annual meeting of the Society for Neuroscience
    • Place of Presentation
      San Diego Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Function of DJ-1 and its therapeutic application to Parkinson's disease2009

    • Author(s)
      Hiroyoshi Ariga
    • Organizer
      The 22nd Biennial Joint Meeting of the International Society for Neurochemistry(ISN)and the Asian Pacific Society for Neurochemistry(APSN)
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PROJECT-20023003
  • [Presentation] Effects of MM-1 and molecular chaperones on formation of polyglutamine aggregation2009

    • Author(s)
      Tashiro, E., Miyazawa, M., Kitaura, H., M., Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Inhibition of PTEN phosphatase activity by the direct interaction of DJ-1 with PTEN under the oxidative conditions2009

    • Author(s)
      Kim, Y-C., Kitaura, H., Taira, T., Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      22rd Annual meeting for International Society for Neurochemistry
    • Place of Presentation
      Busan Exhibition Convention Center (Korea)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Function of DJ-1 and its therapeutic application to Parkinson's disease2009

    • Author(s)
      Ariga, H., Kitamura, Y., Iguchi-Ariga, S. M. M.
    • Organizer
      22rd Annual meeting for International Society for Neurochemistry
    • Place of Presentation
      Busan Exhibition Convention Center (Korea)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Function of DJ-1 and its therapeutic application to Parkinson's disease2009

    • Author(s)
      Hiroyoshi Ariga
    • Organizer
      The 22nd Biennial Joint Meeting of the International Society for Neurochemistry(ISN)and the Asian Pacific Society for Neurochemistry(APSN)
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2009-08-28
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] 大学化合物ライブラリーを用いたパーキンソン病治療薬のin siloco開発2009

    • Author(s)
      有賀寛芳
    • Organizer
      第293回CBI学会
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2009-01-16
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Oxidation of DJ-1-dependent regulation of tyrosine hydroxylase2009

    • Author(s)
      Ishikawa, S., Taira, T., Niki, T., Takahashi, K., Ariga, H., Iguchi-Ariga, S. M. M.
    • Organizer
      The 39th annual meeting of the Society for Neuroscience
    • Place of Presentation
      Chicago Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] Oxidative status of DJ-1-dependent regulation of the p53 signaling2009

    • Author(s)
      Kato, I., Maita, H., Iguchi-Ariga, S. M. M., Ariga, H.
    • Organizer
      22rd Annual meeting for International Society for Neurochemistry
    • Place of Presentation
      Busan Exhibition Convention Center (Korea)
    • Data Source
      KAKENHI-PROJECT-21390014
  • [Presentation] 酸化ストレス防御タンパク質DJ-1とパーキンソン病2008

    • Author(s)
      有賀寛芳
    • Organizer
      第81回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Presentation] Function of DJ-1 and its pharmaceutical application to Parkinson's disease2008

    • Author(s)
      Ariga, H
    • Organizer
      韓国薬学会シンポジウム
    • Place of Presentation
      ホテルソウル教育文化会館
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-20023003
  • [Presentation] 酸化ストレス防御タンパク質DJ-1とパーキンソン病2008

    • Author(s)
      有賀寛芳
    • Organizer
      第81回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390253
  • [Presentation] 酸化ストレン防御タンパク質DJ-1とパーキンソン病2008

    • Author(s)
      有賀寛芳
    • Organizer
      第81回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Presentation] DJ-1, a oxidative stress protein, and Parkinson's disease.2008

    • Author(s)
      Ariga, H. , et. al.
    • Organizer
      Symposium in The 81nd Annual meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Pacifico Yokohama, Yokohama
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390018
  • [Presentation] 酸化ストレス防御タンパク質DJ-1とパーキンソン病2008

    • Author(s)
      有賀寛芳
    • Organizer
      第81回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-18659467
  • [Presentation] 酸化ストレス防御タンパク質DJ-1とパーキンソン病2008

    • Author(s)
      有賀寛芳
    • Organizer
      第81回日本薬理学会年会シンポジウム
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2008-03-17
    • Data Source
      KAKENHI-PROJECT-18023002
  • [Presentation] DJ-1, a oxidative stress protein, and Parkinson's disease.2008

    • Author(s)
      Ariga, H. , et. al.
    • Organizer
      Symposium in The 81nd Annual meeting of The Japanese Pharmacological Society
    • Place of Presentation
      Pacifico Yokohama, Yokohama
    • Year and Date
      2008-03-17
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390253
  • 1.  ARIGA Sanae (90184283)
    # of Collaborated Projects: 26 results
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  • 2.  TAKRA Takahiro.Y. (70197036)
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  • 52.  HINO Shigeo (70012763)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 53.  TAKATSUKI Kiyoshi (80026830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 54.  OSAME Mitsuhiro (10041435)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 55.  YODOI Junji (80108993)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 56.  TAKEICHI Noritoshi (40002133)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 57.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 58.  NISHIDA Yasuyoshi (50107059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 59.  OSHIMURA Mitsuo (20111619)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 60.  NODA Tohru (30146708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 61.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 62.  YOKOTA Jun (10191503)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 63.  NAGAO Minako (40100151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 64.  YAMAMOTO Tadashi (40134621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 65.  TOYOSHIMA Kumao (90029760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 66.  新井 賢一 (00012782)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 67.  瀬川 薫 (30114523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 68.  石浜 明 (80019869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 69.  永田 恭介 (40180492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 70.  渋田 博 (70012721)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 71.  水本 清久 (80092344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 72.  野本 明男 (70112670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 73.  根岸 文子 (40177902)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 74.  WANG Teresa S.-F.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 75.  IVO Galli
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 76.  TERESA S.ーF.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 77.  RUSCONI Sand
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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