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MARUYAMA Ikuro  丸山 征郎

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… Alternative Names

MARUYAMA IKUROU  丸山 征朗

丸山 征朗  マルヤマ イクロウ

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Researcher Number 20082282
Other IDs
External Links
Affiliation (Current) 2025: 鹿児島大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help 2023 – 2024: 鹿児島大学, 医歯学総合研究科, 客員研究員
2015 – 2022: 鹿児島大学, 医歯学総合研究科, 特任教授
2017: 鹿児島大学, 大学院医歯学総合研究科, 特任教授
2013 – 2016: 鹿児島大学, 医歯(薬)学総合研究科, 教授
2012 – 2016: 鹿児島大学, 医歯(薬)学総合研究科, 特任教授 … More
2013 – 2015: 鹿児島大学, 大学院医歯学総合研究科, 特任教授
2014: 鹿児島大学, 医歯学総合研究科, 教授
2013: 鹿児島大学, 大学院医歯(薬)学総合研究科, 特任教授
2010 – 2012: Kagoshima University, 医歯学総合研究科, 特任教授
2010 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 特任教授
2011: 鹿児島大学, 大学院・医歯学総合研究科システム血栓制御学(メディポリス連携医学)講座, 特任講師
2011: 鹿児島大学, 大学院・医歯総合研究科, 特任教授
2010: 鹿児島大学, 医歯(薬)学総合研究科, 教授
2009: 鹿児島大学, 大学院・歯学総合研究科, 教授
2002 – 2009: Kagoshima University, Graduate School of Medicine and Dental Sciences, Professor, 大学院・医歯学総合研究科, 教授
2008: 鹿児島大学, 医歯(薬)学総合研究科, 教授
2006: Kagoshima University, Department of Laboratory and Molecular Medicine, Professor
2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 教授
2001 – 2002: Kagoshima University, Faculty of Medicine, Professor, 歯学部, 教授
1992 – 2002: Kagoshima University, Faculty of Medicine, Professor, 医学部, 教授
2001: 鹿児島大学, 医学部・臨床検査医学, 教授
1999: 鹿児島大学, 医学研究科, 教授
1999: 鹿児島大学, 歯学部, 教授
1994 – 1995: 鹿児島大学, 医学部・臨床検査医学講座, 教授
1993: 鹿児島大学, 医学部・, 教授
1993: 鹿児島大学, 医学部・臨床検査医学, 教授
1988 – 1991: 鹿児島大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Emergency medicine / Hematology / Hematology / Circulatory organs internal medicine / Laboratory medicine / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Anesthesiology/Resuscitation studies / Neurology
Except Principal Investigator
Emergency medicine / Laboratory medicine … More / Circulatory organs internal medicine / 病態科学系歯学(含放射線系歯学) / Neurology / Basic Section 55060:Emergency medicine-related / Basic Section 52010:General internal medicine-related / Veterinary medical science / Neurology / Ophthalmology / 内科学一般 / Basic Section 59010:Rehabilitation science-related / Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 52:General internal medicine and related fields / Digestive surgery / Conservative dentistry / リハビリテーション科学 / Biomedical engineering/Biological material science / Biological Sciences / Eating habits, studies on eating habits / Biomedical engineering/Biological material science / Basic Section 56050:Otorhinolaryngology-related / Basic Section 42020:Veterinary medical science-related / General internal medicine(including psychosomatic medicine) / Neurosurgery / Respiratory organ internal medicine / General surgery / General surgery / Periodontal dentistry / Laboratory medicine / Human pathology / General physiology / Pathological medical chemistry / 膠原病・アレルギー・感染症内科学 / Applied health science / Digestive surgery / General internal medicine (including Psychosomatic medicine) / Periodontal dentistry / Surgical dentistry / Hematology / 内分泌・代謝学 / Pathological medical chemistry Less
Keywords
Principal Investigator
HMGB1 / トロンビン / トロンボモジュリン / DIC / Thrombomodulin / DAMPs / PAMPs / PAMPs / DAMPs / ARDS … More / アポトーシス / トロンビン受容体 / Histones / 感染症 / HMG-1 / 敗血症性ショック / 血管内皮細胞 / exosome / Exosome / エクソソーム / septic shock / anandamide / アナンダマイド / 敗血症 / 感染症性ショック / Thrombin / ヒストン / protein C / thrombomodulin / RAMPs / DAMP / プロテインC / TLR-4 / TLR-2 / トロンボモデュリン / ショック / 細胞・組織 / 循環器・高血圧 / 多臓器不全 / RAGE / HMGB-1 / 糖尿病 / shock / skimming / sludging / Thrombomodulin(TM) / Blood sludging / Blood skimming / 組織因子 / 第Ⅶ因子 / 血栓塞栓症 / 癌 / blood sludging / blood skimming / Trousseau syndrome / Thrombosis / Cancer Procoagulant / 血球成分 / 血漿成分 / 出血 / 血栓・塞栓 / T-TAS / Sludging / Skimming / 血流動態異常 / thrombin / EPCR / Protein C / TM / 修復 / 止血 / 組織損傷 / 生体損傷 / RAMPs / alarmins / Organ failure / メラノーマ細胞株A375 / Alix / Heat shock protein / 糖鎖構造 / microRNA / radical / sprvqis / ock / thromb in / hrombomodulin / 免疫学 / 救命 / 播種性血管内凝固症候群(DIC) / ラディカル / ALI / 2-arachidonylglyceorol / endocannabinoides / High Mobility Group Box-1 / endocannabinoid / 2-arachidonylglycerol(2-AG) / 急性肺障害(ALI) / 2-アラキドニールグリセロール / 内因性マリファナ / polymyxin B / 2-arachidonylflyceorol / endocannabinoids / ポリミキシンB / エンドトキシンショック / 妊娠中毒症 / ショックのメディエーター / 内因性カンナビノイド / atherosclerosis / MAP kinase / Thrombin receptor / アテローム / MAPキナーゼ / Coronary Artery Thrombosis / Coronary Artery / Vascular Smooth Nusle Cells / Thrombin Receptor / Cultured Endothelilal Cells / 膠原病 / 腎系球体 / endothelium / 冠動脈血栓〓 / 冠動脈血栓症 / 冠動脈 / 血管平滑筋細胞 / 培養血管内皮細胞 / cytokine / cyclic AMP / endothelial cells / テラトカルチノ-マ / 血栓症 / 動脈硬化 / ILーI / TNF / プロスタサイクリン / サイクリックAMP / エピジェネティック / HMGB1酸化還元型 / ヒト化モノクローナル抗体 / レドックス状態 / NETs / histones / Shock / Alarmin / IL-18 / IL-1β / Inflammasome / Adenosine / ATP / inflammation / platelet / PAMP / ATP / des-HMGB1 / 止血学 / 血栓 / 発現制御 / 蛋白質 / シグナル伝達 / NF-kB / PAR-1 / inflammasome / 感染病 / 侵襲 / IL-1 / CpG DNA / エンドトキシン / alarmin / 病理学 / 微生物 / 細菌 / 個体死 / 核内蛋白 / 細胞壊死 / TNFα / トロンボモヂュリン / EC-SOD / セレノプロテインP / ASK / p38 / 糖尿病合併症 / 血小板 … More
Except Principal Investigator
敗血症 / 血管内皮細胞 / HMGB1 / DAMPs / トロンボモジュリン / VEGF / 炎症 / アポトーシス / 血管新生 / POEMS syndrome / 動脈硬化 / platelet / Crow-Fukase syndrome / ヒストン / サイトカイン / DIC / 血栓 / megakaryocyte / 炎症性サイトカイン / HTLV-I / miRNA / microRNA / 血栓症 / NF-kB / 血小板 / transgenic mouse / Rho-kinase / 一酸化窒素 / 肝細胞癌 / IL-6 / マクロファージ / 漢方薬 / diabetic retinopathy / atherosclerosis / vascular endothelial growth factor / Angiogenesis / 冠動脈攣縮 / 虚血性心疾患 / 腫瘍 / アラーミン / ヌクレオフォスミン / thrombomodulin / 集中治療医学 / E3ユビキチンリガーゼ / 転写制御 / 滑膜細胞増殖 / シノビオリン / 関節リウマチ / 肝癌 / β2-microglobulin / 小胞体ストレス / 1,5-AF / HMGB-1 / lethality / sepsis / NO / トロンビン / 滑膜細胞 / 遺伝子治療 / エンドセリン / 希少糖 / コンディショニング運動 / 脳神経保護 / non-coding RNA / 犬 / ノンコーディングRNA / 五苓散 / 腎炎 / 予防運動 / 集中治療 / 網膜色素上皮細胞 / anti-inflammatory peptide / IP6K-1 / ROS / IL8 / TNFa / 内皮細胞 / DNAマイクロアレイ / MMP-1 / DX-9065a / gingipain / Porphyromonas gingivalis / Roxithromycin / MMP / ロキシスロマイシン / 血管内皮機能 / リハビリテーション医学 / c-fos mRNA / MRI / Nitric Oxide / 顎関節症 / iNOS / P-selectin / マトリゲル / ヘパリン / bFGF / nitric oxide / 血管リモデリング / mRNA / Thrombomodulin / 抗血栓性 / TEM / Vascular smooth muscle cell / LPS / 血管平滑筋細胞 / NF-κB / Ca^<2+> / PACAP / HTLV-I associated myelopathy / TSP / HAM / 血管平滑筋 / 受容体 / 細胞外ヒストン / マイクロRNA / 単球 / エクソゾーム / 乳腺腫瘍 / メラノーマ / イヌ / 救急医学 / DAMPs / ショック / 加齢黄斑変性 / 網膜剥離 / vitreous body / 硝子体 / VEGF-A / B cell / B細胞 / 神経 / 糖尿病 / 硝子体細胞 / 慢性炎症 / ノックアウトマウス / 基質 / 健康教育プログラム / 食道癌 / RAGE / 蛋白折り畳み異常 / 酸化ストレス / degradome / inflammation / proteome / peptidome / 生体分子 / プロテオーム / 歯周炎 / ネクローシス / 歯肉線維芽細胞 / アナンダマイド / 歯周病 / 1,5-AG / 宇宙飛行 / AP-1 / NF-_KB / 酸化LDL / ずり応力 / 血管形成 / アンチセンスオリゴ / HTLV-I tax / EDRF / 細胞接着分子 / 血管壁弛緩因子 / 血管壁収縮因子 / 線維素溶解現象 / 平滑筋細胞 / マウス喉頭手術 / 気道粘膜再生 / 粘膜傷害抑制 / 喉頭気管粘膜 / 悪性腫瘍 / 感染 / 創傷治癒 / 粘膜免疫 / 上気道傷害 / 腸内細菌叢 / メタボローム / 腸内細菌 / micro vesicles / AI / sncRNA / Y RNA / トランスクリプトーム / 人工知能(AI) / 高齢者 / 活動量 / 有酸素運動 / コンディショニング / 脳梗塞モデル / 認知症 / 予防 / プレコンディショニング / 脳卒中リハビリテーション / 神経可塑性 / 脳梗塞 / 神経炎症 / 機能回復 / リハビリテーション / 遠隔虚血コンディショニング / 運動 / PGC-1α / BDNF / 1,5-anhydro-D-fructose / AMPK / klotho / 酸化 / 老化 / 組織損傷 / メディエーター / 診断 / 治療 / 播種性血管内凝固(DIC) / 抗体 / アイソフォーム / 核内タンパク質 / exosome / ASO / 血管 / p53 / コンドロイチン硫酸 / 播種性血管内凝固症候群 / small RNA / エキソソーム / イヌ腫瘍 / 診断・治療 / 犬腫瘍 / エクソソーム / 炎症制御 / 脳神経疾患 / 脳血管攣縮 / pre-conditioning / 予防的運動 / クモ膜下出血 / 獣医学 / 血栓形成観測システム / 血液凝固検査 / 出血傾向 / T-TAS / 新規血液凝固検査 / 全血血栓観測システム / 播種性血管内凝固 / 血液凝固 / ヘパリン起因性血小板減少症(HIT) / ポイントオブケア / HIT / ヘパリン起因性血小板減少症 / 抗凝固薬 / NETosis / プログラム細胞死 / 白血球 / 生理学 / シグナル伝達 / 細胞・組織 / トランスレーショナルリサーチ / thrombosis / programmed cell death / eryptosis / 赤血球 / molecular clock / program cell death / apoptosis / erythrocyte / セロトニン / prognosis / exhaust platelet / hepatocellular carcinoma / serotonin / 獲得免疫 / ホスホリパーゼA2 / 膠原病関連間質性肺炎 / 炎症性肺疾患 / 呼吸器 / 自然免疫 / choroid / vitrectomy / image analysis / ヒアロサイト / 光干渉断層計 / 網膜疾患 / 画像診断 / 脈絡膜 / 網膜色素上皮 / 画像 / 機械学習 / 画像処理 / 単核球 / invasion / metastasis / invasion-MTT assay / MATRIGEL / basement membrane / モノクローナル抗体 / 細胞膜成分 / レクチン / MTT assay / 再構成基底膜 / Invasion Assay / 転移抑制 / モノクロ-ナル抗体 / 細胞膜 / 癌細胞 / 血行性転移 / 浸潤 / 転移 / invasionーMTTassay / 基底膜 / Rat / Liver / reperfusion injury / 肝虚血再灌流障害 / nerve / brain / proteomics / Syndrome / 脳 / syndrome / プロテオミクス / POEMS / Crow-Fukase / unfolded protein resnonce / ER stress / dialysis related amyloidosis / hemodialysis / 透析アミロイド症 / 血液透析 / Industry-University Alignment / Surface / Polysulfone / Physical Adsorption / Polymeric thinfilm / Biomedical Material / Anticoagulant Activity / プロテインC活性 / 産学官連携 / 表面 / ポリスルホン / 物理吸着 / 高分子超薄膜 / 医療材料 / embryonic lethality / 胎生致死 / 骨髄巨核球 / POEMS症候群 / Crow-Fukase症候群 / Mechanism / DNA microarray / Dentin Hypersensitivity / 発症メカニズム / 象牙質知覚過敏症 / roxithromicin / hepatocarcinogenesis / 1L-8 / TNF-a / IL6 / TNF / 活性酸素 / IL-8 / 肝発癌 / DNA array method / Radiation response gene / Mitochondria / Radiosensitivity / DNAアレイ法 / 放射線応答遺伝子 / ミトコンドリア / 放射線感受性 / CBI receptor antagonist / anandamide / cannabinoid / Acute pancreatitis / TNF-alpha / CB1受容体拮抗薬 / カンナビノイド / 急性膵炎 / Crow-Rukase syndrome / VFGF / Drug for periodontitis / Periodontitis / P.gingivalis / KIAA 0263 / cDNAマイクロアレイ / 活性化血液凝固第X因子 / プロテアーゼ阻害剤 / DX9065a / 歯周病治療薬 / Oxidative stress / Angiotensin II / Arteriosclerosis / Inflammation / 虚血性心臓病 / 冠動脈 / アンジオテンシンII / extracellularmatrix / periodontitis / pulpitis / chronic inflammation / アンチセンスオリゴヌクレオチド / 分化 / 遊走 / tenascin / 歯髄細胞 / 歯髄炎 / in vivo / 歯槽骨再生 / 歯髄再生 / 覆罩 / 細胞外基質 / 歯随炎 / 血管内皮増殖因子 / Transgenic mouse / glioblastoma / coagulation / intraneural injection / isoform / matrix metalloproteinase / nude mouse / neuropathy / naked VEGF cDNA / brain natriuretic peptide / cardiac rehabilitation / heart failure / dilated cardiomyopathy / endothelial function / sauna bathing / thermal therapy / 温熱性血管拡張療法 / 脳ナトリウム利尿ペプチド / 脳性利尿ペプチド / 心臓リハビリテーション / 心不全 / 拡張型心筋症 / サウナ浴 / 温熱療法 / rehabilitation Medicine / Muscle Strengthning / Muscle Specific Transcription Factors / Stretch of Skeletal Muscle / 筋特異的遺伝子転写制御因子 / ミオシンmRNA / 骨格筋の電気刺激 / 筋力増強 / 筋特異的転写制御因子 / 骨格筋のストレッチ / cytokine / serum / TMD / 血清 / Cytokine / Estrogen / MR Images / Posterior Disk Attachment / Joint Pain / Temporomandibular Joint Disorders / TMJ / エストロゲン / MR画像 / 関節円板後部組織 / 関節疼痛 / Contrast media / nitruc oxide / NF-kappa B / Endothelial cells / Late phase / Adverse reaction / NOの産生 / 誘導型NO合成酵素(NOS) / P-selectin,ICAM-1 / NOの生産 / 誘導型NO合成酵素(iNOS) / NF-κBの活性化 / P-selectin、ICAM-1 / 造影剤 / Nltric Oxide / NF-KappaB / 遅延型 / 副作用 / antiseise oligodeoxynucleotides / Tube formation / cornel vascular / phosphorothioate / oligodeoxynucleotides / ホスホロチオエ-ト / FGF / 荷電 / アンチセンス核酸 / 管腔形成 / 角膜血管 / ホスフォロチオエート / オリゴ核酸 / gene therapy / small G proteins / vascular remodeling / coronary artery spasm / atherosclerosis. / cytokines / 冠攣縮 / 血管外膜 / Rho-Kinase / 低分子量G蛋白 / Oxidized LDL / Adhesion molecule / Phenotypic conversion / Vasculogenesis / Vascular endothelial cell / Atherosclerosis / 酸化LDL受容体 / LOX-1 / CD36 / リゾフォスファチジルコリン / 接着分子 / 形質転換 / 粥状動脈硬化 / cloning / metal composition / microgravity / remodeling / bone atrophy / rat / Space-flight / Diffential display / 椎体骨 / 骨モデリング / MEF-2 / ストレス蛋白 / 萎縮 / 傍背柱筋 / クローニング / 微量元素 / 微小重力 / モデリング / 骨萎縮 / ラット / 宇宙旅行 / Prognosis of patient carrying cancer / Sialic acid / MUC5AC mucin / MUC2 mucin / MUC1 mucin / Adenocarcinoma / Squamous cell carcinoma / ムチン抗原 / 肺癌 / in situ hybridization / 消化器癌 / ムチン / 癌患者の予後 / シアル酸 / MUC5ACムチン / MUC2ムチン / MUC1ムチン / 腺癌 / 扁平上皮癌 / surface plasmon resonance / affinity interaction / cellulose film / dialyzer / poly (ethylene) film / antithrombogenicity / immobilization / human thrombomodulin / 医用材料 / 表面プラズモン共鳴(SPR) / 固定化 / フラグメント / static SIMS / angle dependent XPS / liquid-vapor method / micro-domain structure / oxygen permeation / aramid-silicone resin / 人工肺 / 血液適合性 / 機械的特性 / 超薄膜 / マルチブロック共重合体 / アラミドシリコーン樹脂 / 生体適合性 / 熱機械特性他 / 表面解析 / シリコーン / ブロック共重合体 / static-SIMS / angle dependent-XPS / ミクロ相分離構造 / 気液法 / 酸素透過性 / アラミド・シリコーン樹脂 / Aramid-silicon / Mouse / Antisense oligo / Genetherapy / NF-kappaB / Transcription factor / Artherosclerosis / 人工血管 / エンドトキシンショック / アラミドシリコーン / マウス / 転写因子 / myocardial infarction / coronary thrombosis / coronary spasm / arteriosclerosis / ischemic heart disease / inflammatory cytokine / 冠動撃縮 / 冠動脈硬化 / 細胞増殖因子 / 心筋梗塞 / 冠動脈血栓 / PACAP receptor / beta-cells / autocrine / islet / insulin secretion / サイクリックAMP / PACAP受容体 / 膵β細胞 / オートクリン / ランゲルハンス島 / インスリン分泌 / Ocular manifestations / Myopathy / DNA mutation / Type 2 muscle fiber atrophy / Fas antigen / Apoptosis / Mitochondrial encephalomyopathy / タイプ2線維 / 培養血管内皮細胞 / 培養筋芽細胞 / ミトコンドリアDNA / タイプ2筋線維 / Fas mRNA / 眼病変 / ミオパチー / DNA異常 / タイプ2筋線維萎縮 / Fas抗原 / ミトコンドリア脳筋症 / T cell receptor / apoptois / flavivirus / retrovirus / HTLV-1 / 単球マクロファージ / tax遺伝子 / HTLV-I tax遺伝子 / HTLV-Itax遺伝子 / 抗Fas抗体 / 単クローン性滑膜細胞 / HTLV-1 tax遺伝子 / Retrovirus / HTLVーI筋炎 / シェグレン症候群 / HTLVーI関連症候群 / 脊髄症 / HTLVーI脊髄症 / HTLVーI / 成人T細胞白血病ウイルス / HTLV-I associated mylopathy / レトロウイルス / 増殖因子 / 線維素溶解 / 凝固 / 外科系臨床医学 / 血栓性微小血管障害症 / von Willebrand因子 / オートファジー / インフラマソーム / TP53 / 病理学 / 免疫学 / p53遺伝子 / リンパ腫 / 遺伝子導入 / 腫瘍治療 / 腫瘍マーカー / 次世代シーケンス / ファゴサイトーシス / 免疫活性化 / バソプレシン / 敗血症性ショック / 糖尿病網膜症 / デグラドーム / cell reaction / hyaluronan / retina / histone / 硝子体手術 / 細胞破壊物 / ヒアルロン酸 / 血栓形成 / mouse / high endothelial venule / lymph node / nervus system / immune system / angiogenesis / HEV / iron / spleen / lymph / immune / LPS tolerance / 高内皮小静脈 / リンパ節 / 免疫 / アディポサイトカイン / コミュニティー・オーガニゼーション / 動脈硬化予防 / 栄養教育 / インスリン抵抗性 / 代謝異常 / 脂質 / 栄養学 / 補体 / プラットフォーム分子 / 治療薬物 / 超音波 / 薬物治療 / 硝子体免疫 / SDF-1 / T細胞 / 生化学的手法 / 化合物 / コンディショナルノックアウトマウス / 小胞体関連分解 / ユビキチン化 / 分泌 / 滑膜細胞細胞 / 肝硬変 / コンディショナルノックアウト / 分泌タンパク質 / 線維化 / 転写複合体 / ESコビキチンリガーゼ / 親子 / 学童期 / 食教育 / 食育 / 健康教育 / reactive hyperemia / smoking / lifestyle / motivation / health education / endothelial cell / ケモカイン / 炎症と癌化 / Carcinogenseis / Esophageal ca / HCC / 臨床検査 / ELISA / β2mミクログロブリ / β2-ミクログロブリン / MOF / diagnosis / cancer / biomarker / peptide / 蛋白質 / 酵素 / 検査 / 癌 / 質量分析 / バイオマーカー / ペプチド / ペプチドーム / 細胞周期 / 抗炎症作用 / アポプトーシス / メイラード反応 / アスコパイロン-P / エンドトキシン / レセプター / 内因性カンナビノイド / 歯肉溝滲出液 / 炎症抑制 / 歯肉線維牙細胞 / 炎症性細胞浸潤 / 歯肉上皮細胞 / IL-11 / 歯根膜細胞 / HMGBI / 嫌気 / APP / 低酸素・嫌気代謝 / 敗血症・多臓器不全 / HMGB1蛋白 / Ascopyrone-P (APP) / α-1,3-ガラクトース転移酸素 / 樹状細胞 / gene targeting / 内在性レトロウイルス(PERV) / α-1,3-ガラクトース転移酵素 / 制御性T細胞 / ブタ内在性レトロウイルス(PERV) / 転移酵素 / α-1,3-ガラクトース / クローンミニブタ / クラウン系ミニブタ / 異種移植 / decoy ODN / anti-inflammatory oligonucleotide / Guided Bone Regeneration / スズコロイド / 一次リンパ節 / 微少転移 / 予後因子 / 口腔扁平上皮癌 / Myocyte Enhancer factor 2C / 筋アルドラーゼ / ヒートショック蛋白 / 脊椎柱筋 / 筋萎縮 / 無重力 / mRNA Differential Display / CREB / トランスフォーム / HTLV-Itax / プロテインC / トロンビン受容体 / 細胞内カルシウム / TNF-α / アンチセンス療法 / HVJ-リポソーム法 / 骨芽細胞 / 慢性関節リウマチ / HL-60 / PC12 / 神経細胞 / 細胞分化 / 電離放射線 / 血管平滑筋細胞増殖 / 血管内皮細胞障害 / 遊離トロンビン レセプター / DIC(播種性血管内凝固症候群) / トロンビン レセプター / 関節炎 / 成人T細胞白血病 Less
  • Research Projects

    (125 results)
  • Research Products

    (384 results)
  • Co-Researchers

    (207 People)
  •  コンディショニングによる脳保護を考慮した予防リハビリテーションの構築

    • Principal Investigator
      榊間 春利
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kagoshima University
  •  Research for damage suppression and regenerative therapy in vocal fold mucosa

    • Principal Investigator
      山下 勝
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Kagoshima University
  •  circRNA-miRNAによる大動脈弁狭窄症病態解明とバイオマーカー創出の挑戦

    • Principal Investigator
      山口 宗一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kagoshima University
  •  Elucidating the pathophysiological factors for the clinical application using an artificial intelligence analysis to the snRNA transcriptome data of canine tumors

    • Principal Investigator
      Miura Naoki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      Kagoshima University
  •  Reconstruction of metabolism in sepsis by targeting gut microbiota

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kumamoto University
  •  Prevention and Treatment of Age-Related Macular Degeneration by a Novel Functional Monosaccharide with AMPK-regulated Antioxidant Activity

    • Principal Investigator
      Terasaki Hiroto
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kagoshima University
  •  The regulatory mechanism of vascular inflammation convergence by temporal and spatial axes

    • Principal Investigator
      Yamakuchi Munekazu
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Kagoshima University
  •  Large metabolic nexus of the concept of renal deficiency as seen from Klotho

    • Principal Investigator
      Oyama Yoko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kagoshima University
  •  1,5-AF induces anti-aging effects on aging-associated brain diseases by increasing AMPK activity

    • Principal Investigator
      Kikuchi Kiyoshi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Kurume University
  •  Adaptation of the neuroprotective mechanism by conditioning after cerebral ischemia and its application to stroke rehabilitation

    • Principal Investigator
      Sakakima Harutoshi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kagoshima University
  •  The role of p53 in atherosclerosis

    • Principal Investigator
      Yamakuchi Munekazu
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Kagoshima University
  •  Cellular and molecular mechanism of blood sludging/skimming. Causative role of cancer exosomes and their pathophysiological view pointsPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Kagoshima University
  •  Construction of A New Paradigm for Diagnosis and Treatment of Atherosclerosis Obliterans

    • Principal Investigator
      Yamakuchi Munekazu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Kagoshima University
  •  A novel therapeutic strategy targeting HMGB1 isoforms in sepsis

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kagoshima University
  •  Research on the interaction of histones in pathophysiology of sepsis and its application

    • Principal Investigator
      Kawahara Ko-ichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Osaka Institute of Technology
  •  Can Kampo Medicines treat chronic kidney disease? : Challenge to elucidate the inflammation control mechanism of traditional herbal medicine

    • Principal Investigator
      OYAMA Yoko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Kagoshima University
  •  Establishment of smart-diagnosis&treatment for canine tumor by exosome

    • Principal Investigator
      Miura Naoki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  Novel therapeutic proposal for DIC/Shock: from Damage-Sensing/-Control to Damage ResolutionPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Analysis for pro grammed cell death of anuclear platelets and erythrocytes for application of laboratory medicine

    • Principal Investigator
      Hashiguchi Teruto
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Pathophysiological significance of two types of DAMPs, naked- and exosomal type.Principal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Novel simulation technique for diagnosing heparin-induced thrombocytopenia (HIT)

    • Principal Investigator
      Ito Takashi
    • Project Period (FY)
      2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  The evaluation of novel examination of diagnosis of Disseminated intravascular coagulation (DIC) in dogs

    • Principal Investigator
      Iwanaga Tomoko
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  DAMPs as vasospasm and DCI after SAH.

    • Principal Investigator
      Kikuchi Kiyoshi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Kurume University
  •  The mechamism of novel alarmin

    • Principal Investigator
      Kawahara Ko-ichi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Osaka Institute of Technology
  •  Construction of the system of

    • Principal Investigator
      Yamakuchi Munekazu
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Study of comprihensive vitreology

    • Principal Investigator
      SAKAMOTO Taiji
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kagoshima University
  •  Proposal of novel concept, Exosome cargo as a novel DAMPs delivery systemPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Therapeutic strategy targeting extracellular histones in sepsis-associated DIC

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  The role of Endothelial miRNA in the regulation of vascular integrity

    • Principal Investigator
      Yamakuchi Munekazu
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Multi-layered and topological regulatory system of PAMPs and DAMPs. Its relevance in various pathophysiology.Principal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  The analysis of inflammasome activation in extracellular histones

    • Principal Investigator
      Kawahara Ko-ihi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Osaka Institute of Technology
  •  Extracellular histones stimulate endothelial cells to release unusually-large von Willebrand factor multimer: mechanistic insight into the pathogenesis of lethal coagulopathy

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  PAMPs, DAMPs regulation by thrombomodulin(TM). Probable role of epithelial TMPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  The receptor and inhibitor of Nucleophosmin

    • Principal Investigator
      Kawahara Ko-ichi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Osaka Institute of Technology
  •  Identification of novel canine tumor related microRNA for elucidating the pathology and clinical relevance

    • Principal Investigator
      Miura Naoki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Veterinary medical science
    • Research Institution
      Kagoshima University
  •  Extracellular histones as a myocardial depressant factor

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Localization and regulation in reactive sites of DAMPs/PAMPs. Role of ATP from the activated platelesPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Innate immune responses and chronic inflammatory lung diseases

    • Principal Investigator
      Inoue Hiromasa
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kagoshima University
  •  Study of biology and regulation of vitreous body

    • Principal Investigator
      SAKAMOTO Taiji
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kagoshima University
  •  HMGB1-induced vaspressin deficiency contributes to septic shock

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  A role of extracellular histones as mediators of death in sepsis

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Comprehensive regulatory system of PAMPs/DAMPs by TM-PC/EPCR systemPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Nucleophosmin: immunoactivity as a novel alarmin

    • Principal Investigator
      KAWAHARA Ko-ichi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Osaka Institute of Technology
  •  Cellular mechanism in thrombin mediated HMGB1 release. Effect of cluster formation of HMGB1 on the cell-surface receptors.Principal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Establishment and dynamism of des-HMGB1, degraded HMGB1 by thrombin-thrombomodulinPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  DAMPs : novel molecular targets for DIC therapy

    • Principal Investigator
      ITO Takashi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Immunomodulatory effects ofB cell derivedVEGF-A in mice

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  HMGB1の生体内分子修飾による機能変化・病態発現とその制御Principal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Development of a novel anti-inflammation effect in a Thrombomodulin as a platform type molecule

    • Principal Investigator
      KAWAHARA Ko-ichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Osaka Institute of Technology
      Kagoshima University
  •  炎症性の生理活性をもつ“新規アディポサイトカインとしてのHMGB1"の提唱

    • Principal Investigator
      清水 利昭
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kagoshima University
  •  The education of arteriosclerosis prevention that enhanced family support and community support.

    • Principal Investigator
      IMAMURA Kayoko
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Kagoshima Immaculate Heart University
  •  二元的アポトーシス制御因子シノビオリンを標的としたがん研究

    • Principal Investigator
      中島 利博
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Choju Medical Institute, Fukushimura Hospital.
  •  シノビオリンの二方向性シグナル制御の生物学的意義

    • Principal Investigator
      中島 利博
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Choju Medical Institute, Fukushimura Hospital.
  •  Integrated study on implication of Synoviolin in multiprocesses of rheumatoid arthritis.

    • Principal Investigator
      NAKAJIMA Toshihiro
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      Tokyo Medical University
      Choju Medical Institute, Fukushimura Hospital.
  •  Defense system by thrombin-HMGB1 axisPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Study of vitreous body : Analysis of microenvironmental control and development of novel treatment.

    • Principal Investigator
      SAKAMOTO Taiji
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kagoshima University
  •  Diagnostic value of peptidome analyses for protease activated pathological conditions beyond cancer diagnosis

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Established the measurements methods of ER stress levels by using our new antibody.

    • Principal Investigator
      UCHIMURA Tomonori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Identification of Perpetuating Factor for Liver Tissue Inflammation in Hepatic Carcinogenesis

    • Principal Investigator
      UENO Shinichi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kagoshima University
  •  動脈硬化予防に用いる健康学習教材としての血管内皮細胞機能検査の有効性の検証

    • Principal Investigator
      大野 佳子
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied health science
    • Research Institution
      Kagoshima University
  •  壊死細胞由来の核由来生体レスキュー因子:"Alarmins"の概念のスケッチPrincipal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Implementation of the Health Education and Consideration of Physical Condition of Japanese School-age Children and Parents.

    • Principal Investigator
      IMAMURA Kayoko
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Kagoshima Immaculate Heart University
  •  A new therapeutic concept for the treatment against sepsis using a functional material, 1,5-anhydrofructose

    • Principal Investigator
      ABEYAMA Kazuhiro
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Elucidation and reguration of the periodontal disease progression mechanism based on new inflammation adjustments(ANA and HMGB-1)

    • Principal Investigator
      IZUMI Yuichi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Tokyo Medical and Dental University
      Kagoshima University
  •  加熱食品由来の化学反応中間体を用いた生体機能分子修飾:新規創薬法の開発

    • Principal Investigator
      阿邉山 和浩
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General internal medicine (including Psychosomatic medicine)
    • Research Institution
      Kagoshima University
  •  A fundamental study on xenotransplantation

    • Principal Investigator
      TAKAO Sonshin
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kagoshima University
  •  凝固外因系と自然免疫系のクロストークとシナージズムPrincipal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Thrombomodulin : As a regulator of multiple mediatorsPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Evaluation of molecular mechanisms of dialysis related amyloidosis and the diagnosis method of early detection

    • Principal Investigator
      UCHIMURA Tomonori
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Proteomic analysis of Crow-Fukase syndrome

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Kinetics of HMGB1 during ischemia-reperfusion injury of rat liver

    • Principal Investigator
      YAMANOI Akira, 小野 隆司
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Shimane University
  •  重症感染症における炎症誘導因子と致死性因子に対する同時性多重分子標的治療法の開発

    • Principal Investigator
      阿邊山 和浩
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Immobilization of human thrombomodulin onto polymeric thinfilms for biomedical material

    • Principal Investigator
      AKASHI Mitsuru
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Osaka University
  •  Newly development of functional low molecular therapeutics : Study of the pathomechanism of lethal multiple organ failure

    • Principal Investigator
      ABEYAMA Kazuhiro
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Investigations on pathomechanism, diagnosis and treatment in bacterial shock-For preposal of new padadigmPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Emergency medicine
    • Research Institution
      Kagoshima University
  •  Investigation of the unknown factor over stimulating the VEGF prodution in Crow-Fukase syndrome.

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  "死のメディエーター":HMG-1の高感度測定と多臓器不全の診断法の確立Principal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  Radiation Sensitivity and Mitochondrial Related Responding Genes.

    • Principal Investigator
      MAJIMA Hideyuki
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  Fundamental research on identification and its control of the priming factor in liver cancer proliferation

    • Principal Investigator
      UENO Shinichi
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Kagoshima University
  •  Molecular biological analysis of dentin hypersensitivity

    • Principal Investigator
      TORII Mitsuo
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kagoshima University
  •  新規レドックス制御因子:セレノプロテインPの機能とその分子病態Principal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kagoshima University
  •  Molecular and cellular basis of septic shock : Involvement of anandamide and HMG-1Principal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Kagoshima University
  •  Proposal of the new concept, "Platelet VEGF"

    • Principal Investigator
      HASHIGUCHI Teruto
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  A new thrapy for severe acute pancreatitis by regulating the cannabinoid

    • Principal Investigator
      TAKEDA Kazunori
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  口腔扁平上皮癌における予後因子の遺伝子学的、免疫組織学的検討と抗腫瘍効果について

    • Principal Investigator
      田畑 雅士
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kagoshima University
  •  プロテアーゼと新規受容体を介した神経細胞アポトーシスの分子細胞機構Principal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Basic and clinical studies on the role of inflammatory mechanisms in the pathogenesis ischemic heart disease

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Development of a new therapy for periodontitis by regulation of proteinase cascades

    • Principal Investigator
      TORII Mitsuo, 松下 健二
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Kagoshima University
  •  無重力下で誘導されるタイプI 筋萎縮関連新規遺伝子のクローニングと分子機能解析

    • Principal Investigator
      北島 勲
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Research for the pathogenesis and treatment of Crow-Fukase syndrome

    • Principal Investigator
      ARIMURA Kimiyoshi
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Application of vascular endothelial growth factor in conservative dentistry

    • Principal Investigator
      TORII Mitsuo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      KagoshimaUniversity
  •  Involvement of thrombin/thrombin receptor signaling in the development of vascular remodelingPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kagoshima University
  •  The Molecular Mechanism of Late Phase Adverse Reaction of Contrast Media

    • Principal Investigator
      NOIKURA Takenori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  Analysis of Angiogenesis for the Intra-Articular Lesions of Temporomandibular Joint Disorders by Mechanical Stress

    • Principal Investigator
      SATO Tsuyoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  A study of NO in serum from patient with temporomandibular disorders

    • Principal Investigator
      HASEGAWA Hiroko, 奥 猛志
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  MOLECULAR BIOLOGICAL RESEARCH ABOUT EFFECTS OF NEURONAL AND MUSCULAR REHABILITATION

    • Principal Investigator
      TANAKA Nobuyuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      リハビリテーション科学
    • Research Institution
      KAGOSHIMA UNIVERSITY
  •  The Clinical Study for the Mechanism of Thermal Therapy to Patients with Chronic Heart Failure and Prognosis

    • Principal Investigator
      TEI Chuwa
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      リハビリテーション科学
    • Research Institution
      Kagoshima University
  •  Molecular Mechanism of Atherosclerosis

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      KYOTO UNIVERSITY
  •  Experimental and Clinical Studies on the Role of Inflammatory Mechanisms in the Pathogenesis of Ischemic Heart Disease

    • Principal Investigator
      SHIMOKAWA Horoaki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      KYUSHU UNIVERSITY
  •  Molecular constructions of oligodeoxynucleotides binding to bFGF targeting for angiogenesis

    • Principal Investigator
      KITAJIMA Isao
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kagoshima University
  •  動脈硬化の分子機構

    • Principal Investigator
      KITA Toru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyoto University
  •  電離放射線による細胞の分化とアポトーシスの分子機構に関する研究

    • Principal Investigator
      河野 一典
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  トロンビン受容体遊離ペプチド高感度アッセイ系の確立と内皮細胞「活性化」の診断Principal Investigator

    • Principal Investigator
      丸山 征郎
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  関節リウマチの滑膜細胞増殖情報伝達機構解明とその制御によるアンチセンス療法開発

    • Principal Investigator
      北島 勲
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      内科学一般
    • Research Institution
      Kagoshima University
  •  HTLV-I tax遺伝子発現を介するアポトーシス誘導の分子生物学機構の解明Principal Investigator

    • Principal Investigator
      丸山 征郎, SHINMYOUZU Kohichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  Expression of new cell-cell adhesion molecule and mucin genes in cancers : its relationship with invasion or metastasis of cancers

    • Principal Investigator
      YONEZAWA Suguru
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Kagoshima University
  •  Molecular cloning related to skeletal or muscle atrophy under microgravity

    • Principal Investigator
      KITAJIMA Isao
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory medicine
    • Research Institution
      Kagoshima University
  •  脳血栓準備状態の把握に関する研究-流血中遊離トロンビンレセプターの測定系の確立とその臨床応用-

    • Principal Investigator
      丸山 芳一
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  The role of inflammatory mechanisms in the pathogenesis of ischemic heart disease. Basic and clinical studies.

    • Principal Investigator
      SHIMOKAWA Hiroaki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kyushu University
  •  Gene therapy for atherosclerosis by inhibition of nuclear transcriptional factor

    • Principal Investigator
      KITAJIMA Isao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Kagoshima University
  •  The development of the high-performance resin for medical use by using the multi-block copolymer of aramid and silicone

    • Principal Investigator
      SERIZAWA Takeshi, 明石 満
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kagoshima University
  •  A study on human thrombomodulin-immobilized antithrombogenic biomaterials

    • Principal Investigator
      AKASHI Mitsuru, 岸田 晶夫
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      Kagoshima University
  •  アンチセンスオリゴ法によるHTLV-I関連疾患に対する遺伝子調節治療法の開発

    • Principal Investigator
      KITAJIMA Isao
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kagoshima University
  •  Extraordinarily Potent Insulinotropin PACAP : Its Characterization as a Pancreatic Peptide and Action Mechanisms in Islet beta-Cells

    • Principal Investigator
      YADA Toshihiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Kagoshima University
  •  血管病変の成因究明を指向した血管内皮細胞の特性と機能に関する総合的研究

    • Principal Investigator
      室田 誠逸
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular Genetics Program in the Pathogenesis of Rheumatoid Arthritis Institute of Medical Science

    • Principal Investigator
      NISHIOKA Kusuki
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内科学一般
    • Research Institution
      St.Marianna University School of Medicine
  •  Study of apoptosis in mitochondrial diseases

    • Principal Investigator
      NAKAGAWA Masanori
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Kagoshima University
  •  Regulation of Expression of Thrombomodulin on the Cultured Human Umbilical Vein Endothelila Cells and Pathomechanism of ThrombosisPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      KAGOSHIMA UNIVERSITY
  •  血管病変の成因究明を指向した血管内皮細胞の特性と機能に関する総合的研究

    • Principal Investigator
      室田 誠逸
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokyo Medical and Dental University
  •  RESEARCH FOR THE PATHOMECHANISM, EPIDEMILOGY AND TREATMENTS FOR HAM AND HTLV-I RELATED DISORDERS.

    • Principal Investigator
      OSAME Mitsuhiro
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      KAGOSHIMA UNIVERSITY
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      居石 克夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  An Investigation of the Expression of Thrombomodulin in Cultured Human Umbilical Vein Endothelial CellsPrincipal Investigator

    • Principal Investigator
      MARUYAMA Ikuro
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Hematology
    • Research Institution
      Kagoshima University
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      SUEISHI Katsuo
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  血管内皮細胞由来の血栓調節因子の機能解析

    • Principal Investigator
      居石 克夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Studies for Control of Metastasis Using Monoclonal Antibodies to Components of Blood-borne Metastatic Cancer Cells Surface

    • Principal Investigator
      SHIMAZU Hisaaki
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kagoshima University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] 血栓止血血管学2015

    • Author(s)
      一瀬白帝、丸山征郎、内山真一郎、山口宗一
    • Total Pages
      250
    • Publisher
      金芳堂
    • Data Source
      KAKENHI-PROJECT-15K15196
  • [Book] 血管内皮細胞研究フロンティア2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Publisher
      血管内皮細胞による炎症・凝固系制御(炎症反応系と血液凝固系のクロストーク)
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Book] 血管の発生と新生-基礎と臨床- 血小板性VEGF増多症としてのCrow-Fukase症候群2003

    • Author(s)
      橋口照人, 梅原藤雄, 有村公良, 丸山征郎
    • Publisher
      メディカルレビュー社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590901
  • [Book] 血管の発生と新生 -基礎と臨床- 血小板性VEGF増多症としてのCrow-Fukase症候群(p60-67)2003

    • Author(s)
      橋口照人, 梅原藤雄, 有村公良, 丸山征郎
    • Total Pages
      149
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-15590901
  • [Journal Article] Stimulation of functional recovery via neurorepair mechanisms by the traditional Japanese Kampo medicine, Ninjin'yoeito, and physical exercise in a rat ischemic stroke model2023

    • Author(s)
      Tani Akira、Sakakima Harutoshi、Otsuka Shotaro、Mizuno Keita、Nakanishi Kazuki、Norimatsu Kosuke、Takada Seiya、Matsuoka Teruki、Matsuzaki Ryoma、Nakakogawa Tomomi、Maruyama Ikuro
    • Journal Title

      Journal of Ethnopharmacology

      Volume: 302 Pages: 115927-115927

    • DOI

      10.1016/j.jep.2022.115927

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17632, KAKENHI-PROJECT-20H04039
  • [Journal Article] Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats2023

    • Author(s)
      Otsuka Shotaro、Itashiki Yuki、Tani Akira、Matsuoka Teruki、Takada Seiya、Matsuzaki Ryoma、Nakanishi Kazuki、Norimatsu Kosuke、Tachibe Yuta、Kitazato Riho、Nojima Nao、Kakimoto Shogo、Kikuchi Kiyoshi、Maruyama Ikuro、Sakakima Harutoshi
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 2158-2158

    • DOI

      10.1038/s41598-023-29475-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K17632, KAKENHI-PROJECT-23K16543, KAKENHI-PROJECT-20H04039
  • [Journal Article] 1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5'-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway2023

    • Author(s)
      Kikuchi K, Otsuka S, Takada S, Nakanishi K, Setoyama K, Sakakima H, Tanaka E, Maruyama I
    • Journal Title

      Aging

      Volume: 15 Issue: 21 Pages: 11740-11763

    • DOI

      10.18632/aging.205228

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K10949, KAKENHI-PROJECT-20K11640
  • [Journal Article] Damage-associated molecular patterns and fibrinolysis perturbation are associated with lethal outcomes in traumatic injury.2023

    • Author(s)
      Shimono K, Ito T, Kamikokuryo C, Niiyama S, Yamada S, Onishi H, Yoshihara H, Maruyama I, Kakihana Y.
    • Journal Title

      Thromb J

      Volume: 21(1) Issue: 1 Pages: 91-91

    • DOI

      10.1186/s12959-023-00536-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09291, KAKENHI-PROJECT-21H03033
  • [Journal Article] E8002 Reduces Adhesion Formation and Improves Joint Mobility in a Rat Model of Knee Arthrofibrosis2022

    • Author(s)
      Takada Seiya、Setoyama Kentaro、Norimatsu Kosuke、Otsuka Shotaro、Nakanishi Kazuki、Tani Akira、Nakakogawa Tomomi、Matsuzaki Ryoma、Matsuoka Teruki、Sakakima Harutoshi、Tancharoen Salunya、Maruyama Ikuro、Tanaka Eiichiro、Kikuchi Kiyoshi、Uchikado Hisaaki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 3 Pages: 1239-1239

    • DOI

      10.3390/ijms23031239

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K19312, KAKENHI-PROJECT-20J14080, KAKENHI-PROJECT-20K11640
  • [Journal Article] Preconditioning Exercise in Rats Attenuates Early Brain Injury Resulting from Subarachnoid Hemorrhage by Reducing Oxidative Stress, Inflammation, and Neuronal Apoptosis2021

    • Author(s)
      Otsuka Shotaro、Setoyama Kentaro、Takada Seiya、Nakanishi Kazuki、Terashi Takuto、Norimatsu Kosuke、Tani Akira、Sakakima Harutoshi、Maruyama Ikuro、Tancharoen Salunya、Tanaka Eiichiro、Kikuchi Kiyoshi
    • Journal Title

      Molecular Neurobiology

      Volume: 58 Issue: 11 Pages: 5602-5617

    • DOI

      10.1007/s12035-021-02506-7

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K19312, KAKENHI-PROJECT-20H04039, KAKENHI-PROJECT-20J14080, KAKENHI-PROJECT-20K11640
  • [Journal Article] Effects of detraining on preconditioning exercise-induced neuroprotective potential after ischemic stroke in rats2021

    • Author(s)
      Otsuka Shotaro、Sakakima Harutoshi、Tani Akira、Nakanishi Kazuki、Takada Seiya、Norimatsu Kosuke、Maejima Hiroshi、Maruyama Ikuro
    • Journal Title

      Brain Structure and Function

      Volume: 226 Issue: 7 Pages: 2169-2180

    • DOI

      10.1007/s00429-021-02317-5

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K19312, KAKENHI-PROJECT-20H04039, KAKENHI-PROJECT-20H04048, KAKENHI-PROJECT-20J14080
  • [Journal Article] 1,5-Anhydro-D-fructose Protects against Rotenone-Induced Neuronal Damage In Vitro through Mitochondrial Biogenesis2021

    • Author(s)
      Kasamo Yuki、Kikuchi Kiyoshi、Yamakuchi Munekazu、Otsuka Shotaro、Takada Seiya、Kambe Yuki、Ito Takashi、Kawahara Ko-ichi、Arita Kazunori、Yoshimoto Koji、Maruyama Ikuro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Issue: 18 Pages: 9941-9941

    • DOI

      10.3390/ijms22189941

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K19312, KAKENHI-PROJECT-21H03037, KAKENHI-PROJECT-20K11640, KAKENHI-PROJECT-21K19454, KAKENHI-PROJECT-21K19544
  • [Journal Article] Endotheliopathy in septic conditions: mechanistic insight into intravascular coagulation2021

    • Author(s)
      Ito Takashi、Kakuuchi Midori、Maruyama Ikuro
    • Journal Title

      Critical Care

      Volume: 25 Issue: 1 Pages: 95-95

    • DOI

      10.1186/s13054-021-03524-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904
  • [Journal Article] Protective effects of recombinant human soluble thrombomodulin on ischemia reperfusion injury of spinal cord in rabbits2021

    • Author(s)
      Imagama I, Kawahara K, Ueno H, Maruyama I, Imoto H
    • Journal Title

      Medical Journal of Kagoshima University

      Volume: 73 Pages: 16-22

    • NAID

      120007001538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02906
  • [Journal Article] Potential roles of 1,5-anhydro-d-fructose in modulating gut microbiome in mice2021

    • Author(s)
      Ito Takashi、Totoki Takaaki、Takada Seiya、Otsuka Shotaro、Maruyama Ikuro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 19648-19648

    • DOI

      10.1038/s41598-021-99052-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21H03033
  • [Journal Article] Circulating Syndecan-1 as a Predictor of Persistent Thrombocytopenia and Lethal Outcome: A Population Study of Patients With Suspected Sepsis Requiring Intensive Care2021

    • Author(s)
      Hatanaka Kosaku、Ito Takashi、Madokoro Yutaro、Kamikokuryo Chinatsu、Niiyama Shuhei、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Frontiers in Cardiovascular Medicine

      Volume: 8 Pages: 730553-730553

    • DOI

      10.3389/fcvm.2021.730553

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H03033, KAKENHI-PROJECT-20K09291
  • [Journal Article] Effects of thrombomodulin alfa on hemostatic parameters in disseminated intravascular coagulation: Post hoc analysis of a phase 3 randomized controlled trial2020

    • Author(s)
      Ito Takashi、Maruyama Ikuro、Shimazaki Shuji、Yamamoto Yasuhiro、Aikawa Naoki、Hirayama Akio、Honda Goichi、Saito Hidehiko
    • Journal Title

      Research and Practice in Thrombosis and Haemostasis

      Volume: 4 Issue: 7 Pages: 1141-1149

    • DOI

      10.1002/rth2.12419

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904
  • [Journal Article] TLR4/MD-2 is a receptor for extracellular nucleophosmin 12020

    • Author(s)
      Nakatomi Kota、Ueno Hikari、Ishikawa Yuto、Salim Ronny、Mori Yuki、Kanemoto Issey、Tancharoen Salunya、Kikuchi Kiyoshi、Miura Naoki、Omori Taketo、Okuda?ashitaka Emiko、Matsumura Kiyoshi、Imaizumi Hitoshi、Motomiya Yoshihiro、Maruyama Ikuro、Kawahara Ko-Ichi
    • Journal Title

      Biomedical Reports

      Volume: 14 Issue: 2 Pages: 1-6

    • DOI

      10.3892/br.2020.1397

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11640, KAKENHI-PROJECT-18H02906
  • [Journal Article] E8002 Inhibits Peripheral Nerve Adhesion by Enhancing Fibrinolysis of l-Ascorbic Acid in a Rat Sciatic Nerve Model2020

    • Author(s)
      Kikuchi Kiyoshi、Setoyama Kentaro、Takada Seiya、Otsuka Shotaro、Nakanishi Kazuki、Norimatsu Kosuke、Tani Akira、Sakakima Harutoshi、Kawahara Ko-ichi、Hosokawa Kazuya、Kiyama Ryoji、Sumizono Megumi、Tancharoen Salunya、Maruyama Ikuro、Hattori Gohsuke、Morioka Motohiro、Tanaka Eiichiro、Uchikado Hisaaki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 11 Pages: 3972-3972

    • DOI

      10.3390/ijms21113972

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K11640, KAKENHI-PROJECT-18K08955
  • [Journal Article] Recombinant thrombomodulin alleviates oxidative stress without compromising host resistance to infection in rats infected with methicillin-resistant Staphylococcus aureus2020

    • Author(s)
      Ito Takashi、Shrestha Binita、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 17413-17413

    • DOI

      10.1038/s41598-020-74529-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904
  • [Journal Article] Leukocyte-derived extracellular DNA contributes to abnormal pressure elevation in the extracorporeal circulation circuit2020

    • Author(s)
      Yashima Nozomi、Ito Takashi、Kajiyama Kenji、Maeda Hiroyuki、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1

    • DOI

      10.1038/s41598-019-57173-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18K19587
  • [Journal Article] Dynamics of Soluble Thrombomodulin and Circulating miRNAs in Patients with Atrial Fibrillation Undergoing Radiofrequency Catheter Ablation2019

    • Author(s)
      Namino F, Yamakuchi M, Iriki Y, Okui H, Ichiki H, Maenosono R, Oketani N, Masamoto I, Miyata M, Horiuchi M, Hashiguchi T, Ohishi M, Maruyama I
    • Journal Title

      Clin Appl Thromb Hemost

      Volume: 25 Pages: 107602961985157-107602961985157

    • DOI

      10.1177/1076029619851570

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09593, KAKENHI-PROJECT-19K17608, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Circulating histone H3 levels in septic patients are associated with coagulopathy, multiple organ failure, and death: a single-center observational study2019

    • Author(s)
      Yokoyama Yayoi、Ito Takashi、Yasuda Tomotsugu、Furubeppu Hiroaki、Kamikokuryo Chinatsu、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Thrombosis Journal

      Volume: 17 Issue: 1 Pages: 1-1

    • DOI

      10.1186/s12959-018-0190-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Generation of the heterogeneity of extracellular vesicles by membrane organization and sorting machineries2019

    • Author(s)
      Harada Yoichiro、Suzuki Takehiro、Fukushige Tomoko、Kizuka Yasuhiko、Yagi Hirokazu、Yamamoto Mika、Kondo Kiyotaka、Inoue Hiromasa、Kato Koichi、Taniguchi Naoyuki、Kanekura Takuro、Dohmae Naoshi、Maruyama Ikuro
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1863 Issue: 4 Pages: 681-691

    • DOI

      10.1016/j.bbagen.2019.01.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] N‐glycome inheritance from cells to extracellular vesicles in B16 melanomas2019

    • Author(s)
      Harada Yoichiro、Kizuka Yasuhiko、Tokoro Yuko、Kondo Kiyotaka、Yagi Hirokazu、Kato Koichi、Inoue Hiromasa、Taniguchi Naoyuki、Maruyama Ikuro
    • Journal Title

      FEBS Letters

      Volume: 印刷中 Issue: 9 Pages: 942-951

    • DOI

      10.1002/1873-3468.13377

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Serum histone H3 levels and platelet counts are potential markers for coagulopathy with high risk of death in septic patients: a single-center observational study2019

    • Author(s)
      Ito Takashi、Totoki Takaaki、Yokoyama Yayoi、Yasuda Tomotsugu、Furubeppu Hiroaki、Yamada Shingo、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Journal of Intensive Care

      Volume: 7 Issue: 1 Pages: 63-63

    • DOI

      10.1186/s40560-019-0420-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Application of high-mannose-type glycan-specific lectin from Oscillatoria Agardhii for affinity isolation of tumor-derived extracellular vesicles2019

    • Author(s)
      Yamamoto Mika、Harada Yoichiro、Suzuki Takehiro、Fukushige Tomoko、Yamakuchi Munekazu、Kanekura Takuro、Dohmae Naoshi、Hori Kanji、Maruyama Ikuro
    • Journal Title

      Analytical Biochemistry

      Volume: 580 Pages: 21-29

    • DOI

      10.1016/j.ab.2019.06.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08272, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02734, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19523, KAKENHI-PROJECT-18K19587
  • [Journal Article] Effects of glycemic control and hypoglycemia on Thrombus formation assessed using automated microchip flow chamber system: an exploratory observational study.2019

    • Author(s)
      Yamamoto K, Ito T, Nagasato T, Shinnakasu A, Kurano M, Arimura A, Arimura H, Hashiguchi H, Deguchi T, Maruyama I, Nishio Y.
    • Journal Title

      Thromb J.

      Volume: 17 Issue: 1

    • DOI

      10.1186/s12959-019-0206-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Immunological evidence for in vivo production of novel advanced glycation end-products from 1,5-anhydro-D-fructose, a glycogen metabolite2019

    • Author(s)
      Sakasai-Sakai Akiko、Takata Takanobu、Suzuki Hirokazu、Maruyama Ikuro、Motomiya Yoshihiro、Takeuchi Masayoshi
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 10194-10194

    • DOI

      10.1038/s41598-019-46333-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K11003, KAKENHI-PROJECT-18K11139, KAKENHI-PROJECT-16H01811, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Recombinant Thrombomodulin Suppresses Histone-Induced Neutrophil Extracellular Trap Formation2019

    • Author(s)
      Shrestha Binita、Ito Takashi、Kakuuchi Midori、Totoki Takaaki、Nagasato Tomoka、Yamamoto Mika、Maruyama Ikuro
    • Journal Title

      Frontiers in Immunology

      Volume: 10 Pages: 2535-2535

    • DOI

      10.3389/fimmu.2019.02535

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587
  • [Journal Article] Comparison between blood coagulability in the intra-atrial and peripheral regions during the acute phase after rapid atrial pacing2019

    • Author(s)
      Yamada S, Hirao D, Miura N, Iwanaga T, Kawaguchi T, Yoshimura A, Oomori T, Nagasato T, Maruyama I, Fukushima R
    • Journal Title

      Exp. Anim.

      Volume: 68 Issue: 2 Pages: 137-146

    • DOI

      10.1538/expanim.18-0100

    • NAID

      130007642989

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08054, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-17H03926, KAKENHI-PROJECT-16K10746, KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-16H05845
  • [Journal Article] Application of a Novel Anti-Adhesive Membrane, E8002, in a Rat Laminectomy Model.2018

    • Author(s)
      Kikuchi K, Setoyama K, Terashi T, Sumizono M, Tancharoen S, Otsuka S, Takada S, Nakanishi K, Ueda K, Sakakima H, Kawahara KI, Maruyama I, Hattori G, Morioka M, Tanaka E, Uchikado H.
    • Journal Title

      Int J Mol Sci.

      Volume: 19(5) Issue: 5 Pages: 1-9

    • DOI

      10.3390/ijms19051513

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-18H02906, KAKENHI-PROJECT-16K10746
  • [Journal Article] Circulating activated protein C levels are not increased in septic patients treated with recombinant human soluble thrombomodulin2018

    • Author(s)
      Arishima Takuro、Ito Takashi、Yasuda Tomotsugu、Yashima Nozomi、Furubeppu Hiroaki、Kamikokuryo Chinatsu、Futatsuki Takahiro、Madokoro Yutaro、Miyamoto Shotaro、Eguchi Tomohiro、Haraura Hiroyuki、Maruyama Ikuro、Kakihana Yasuyuki
    • Journal Title

      Thrombosis Journal

      Volume: 16 Issue: 1 Pages: 24-24

    • DOI

      10.1186/s12959-018-0178-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-17H04363
  • [Journal Article] Circulating histone H3 levels are increased in septic mice in a neutrophil-dependent manner: preclinical evaluation of a novel sandwich ELISA for histone H32018

    • Author(s)
      Ito Takashi、Nakahara Mayumi、Masuda Yoshiki、Ono Sachie、Yamada Shingo、Ishikura Hiroyasu、Imaizumi Hitoshi、Kamikokuryo Chinatsu、Kakihana Yasuyuki、Maruyama Ikuro
    • Journal Title

      Journal of Intensive Care

      Volume: 6 Issue: 1 Pages: 79-79

    • DOI

      10.1186/s40560-018-0348-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-18H02904
  • [Journal Article] Comparison of chronological changes in blood characteristics in the atrium and peripheral vessels after the development of non-valvular atrial fibrilation2018

    • Author(s)
      Yamada S,Hirao D, Miura N, Iwanaga T, Kawaguchi T,Yoshimura A, Oomori T, Nagasato T, Maruyama I, Fukushima R
    • Journal Title

      Thrombosis Reserch

      Volume: 171 Pages: 31-37

    • DOI

      10.1016/j.thromres.2018.09.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08054, KAKENHI-PROJECT-18K19587, KAKENHI-PROJECT-16H05845
  • [Journal Article] HMGB proteins and arthritis.2018

    • Author(s)
      Taniguchi N, Kawakami Y, Maruyama I, Lotz M.
    • Journal Title

      Hum Cell

      Volume: 31(1) Issue: 1 Pages: 1-9

    • DOI

      10.1007/s13577-017-0182-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04363, KAKENHI-PROJECT-15K10484, KAKENHI-PROJECT-18K09036
  • [Journal Article] Uric acid enhances alteplase-mediated thrombolysis as an antioxidant.2018

    • Author(s)
      Kikuchi K, Setoyama K, Tanaka E, Otsuka S, Terashi T,Nakanishi K, Takada S, Sakakima H, Ampawong S, Kawahara KI, Nagasato T, Hosokawa K, Harada Y, YamamotoM, Kamikokuryo C, Kiyama R, Morioka M, Ito T, Maruyama I, Tancharoen S.
    • Journal Title

      Sci Rep.

      Volume: 8(1) Issue: 1 Pages: 15844-15844

    • DOI

      10.1038/s41598-018-34220-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-18H02906, KAKENHI-PROJECT-16K10746
  • [Journal Article] 敗血症における血栓形成の生理と病理2017

    • Author(s)
      八島望, 伊藤隆史, 垣花泰之, 丸山征郎
    • Journal Title

      日本外科感染症学会雑誌

      Volume: 14 Pages: 705-711

    • Data Source
      KAKENHI-PROJECT-15H05684
  • [Journal Article] Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis.2017

    • Author(s)
      Kikuchi K, Setoyama K, Kawahara KI, Nagasato T, Terashi T, Ueda K, Nakanishi K, Otsuka S, Miura N, Sameshima H, Hosokawa K,Harada Y, Shrestha B, Yamamoto M, Morimoto-Yamashita Y, Kikuchi H, Kiyama R, Kamikokuryo C, Tancharoen S, Sakakima H, Morioka M, Tanaka E, Ito T, Maruyama I.
    • Journal Title

      Oxid Med Cell Longev.

      Volume: Article ID 6873281 Issue: 1 Pages: 14-14

    • DOI

      10.1155/2017/6873281

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05845, KAKENHI-PROJECT-15H05684
  • [Journal Article] Decreased Expression of Thrombomodulin in Endothelial Cells by Fibroblast Growth Factor-23/α-Klotho.2017

    • Author(s)
      Tanaka K, Salunya T, Motomiya Y, Motomiya Y, Oyama Y, Yamakuchi M, Maruyama I.
    • Journal Title

      Ther Apher Dial

      Volume: 21(4) Issue: 4 Pages: 395-404

    • DOI

      10.1111/1744-9987.12524

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Journal Article] Potential diagnostic markers for disseminated intravascular coagulation of sepsis2016

    • Author(s)
      Toshiaki Iba, Takashi Ito, Ikuro Maruyama, Bernd Jilma, Thorsten Brenner, Marcella C.A. Muller, Nicole P. Juffermans, Jecko Thachil
    • Journal Title

      Blood Reviews

      Volume: 30 Issue: 2 Pages: 149-155

    • DOI

      10.1016/j.blre.2015.10.002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05684, KAKENHI-PROJECT-25462831, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-26293385
  • [Journal Article] HMGB1 Promotes Intraoral Palatal Wound Healing through RAGE-Dependent Mechanisms.2016

    • Author(s)
      Tancharoen S, Gando S, Binita S, Nagasato T, Kikuchi K, Nawa Y, Dararat P, Yamamoto M, Narkpinit S, Maruyama I.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 17(11) Issue: 11 Pages: 1961-1961

    • DOI

      10.3390/ijms17111961

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-16K15763
  • [Journal Article] HMGB1 is secreted by 3T3-L1 adipocytes through JNK signaling and the secretion is partially inhibited by adiponectin.2016

    • Author(s)
      Shimizu T, Yamakuchi M, Biswas KK, Aryal B, Yamada S, Hashiguchi T, Maruyama I.
    • Journal Title

      Obesity (Silver Spring).

      Volume: 24(9) Issue: 9 Pages: 1913-21

    • DOI

      10.1002/oby.21549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-16K15763
  • [Journal Article] Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases2016

    • Author(s)
      Takashi Ito, Yasuyuki Kakihana & Ikuro Maruyama
    • Journal Title

      Expert Opinion on Therapeutic Targets

      Volume: 20 Issue: 2 Pages: 151-158

    • DOI

      10.1517/14728222.2016.1086750

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05684
  • [Journal Article] Secondhand smoke exposure-induced nucleocytoplasmic shuttling of HMGB1 in a rat premature skin aging model.2015

    • Author(s)
      Chaichalotornkul S, Nararatwanchai T, Narkpinit S, Dararat P, Kikuchi K, Maruyama I, Tancharoen S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 456(1) Issue: 1 Pages: 92-7

    • DOI

      10.1016/j.bbrc.2014.11.040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-26670790
  • [Journal Article] Gene transfer of high-mobility group box 1 box-A domain in a rat acute liver failure model2015

    • Author(s)
      Tanaka, M
    • Journal Title

      Journal of Surgical Research

      Volume: 194 Issue: 2 Pages: 571-580

    • DOI

      10.1016/j.jss.2014.11.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591888, KAKENHI-PROJECT-26670790, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-26293385
  • [Journal Article] The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.2015

    • Author(s)
      Fujita H, Yagishita N, Aratani S, Saito-Fujita T, Morota S, Yamano Y, Hansson MJ, Inazu M, Kokuba H, Sudo K, Sato E, Kawahara K, Nakajima F, Hasegawa D, Higuchi I, Sato T, Araya N, Usui C, Nishioka K, Nakatani Y, Maruyama I, Usui M, Hara N, Uchino H, Elmer E, Nishioka K, Nakajima T.
    • Journal Title

      EMBO J.

      Volume: 34 Issue: 8 Pages: 1042-55

    • DOI

      10.15252/embj.201489897

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-26670793, KAKENHI-PROJECT-26461478, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293385
  • [Journal Article] Cleavage of host cytokeratin-6 by lysine-specific gingipain induces gingival inflammation in periodontitis patients.2015

    • Author(s)
      Tancharoen S, Matsuyama T, Kawahara K, Tanaka K, Lee LJ, Machigashira M, Noguchi K, Ito T, Imamura T, Potempa J, Kikuchi K,Maruyama I.
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 2 Pages: e0117775-e0117775

    • DOI

      10.1371/journal.pone.0117775

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390402, KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26670790, KAKENHI-PROJECT-26670793, KAKENHI-PROJECT-25460498
  • [Journal Article] Structure and function of Thrombomodulin, a molecule which expressed on the endothelial cell surface and acts as anti-thrombogenic and antiinflammatory in the closed circulatory system2015

    • Author(s)
      Maruyama I.
    • Journal Title

      Seikagaku.

      Volume: 87(2) Pages: 188-93

    • NAID

      40020461501

    • Data Source
      KAKENHI-PROJECT-26293385
  • [Journal Article] Upregulation of non-β Cell-derived Vascular Endothelial Growth FactorA Increases Small Clusters of Insulin producing Cells in the Pancreas.2014

    • Author(s)
      Takenouchi K, Shrestha B, Yamakuchi M, Yoshinaga M, Arimura N, Kawaguchi H, Nagasato T, Feil R, Kawahara K-I, Sakamoto T, Maruyama I, Hashiguchi T.
    • Journal Title

      Experimental and Clinical Endocrinology & Diabetes

      Volume: in press Issue: 05 Pages: 308-15

    • DOI

      10.1055/s-0034-1371811

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293130
  • [Journal Article] Toxic effects of extracellular histones and their neutralization by vitreous in retinal detachment.2014

    • Author(s)
      Kawano H, Ito T, Yamada S, Hashiguchi T, Maruyama I, Hisatomi T, Nakamura M, Sakamoto T.
    • Journal Title

      Laboratory Investigations

      Volume: 94(5) Issue: 5 Pages: 569-585

    • DOI

      10.1038/labinvest.2014.46

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390396, KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659765, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25670763, KAKENHI-PROJECT-26293385, KAKENHI-PROJECT-26670789
  • [Journal Article] Antithrombotic effects of PAR1 and PAR4 antagonists evaluated under flow and static conditions2014

    • Author(s)
      Hosokawa K, Ohnishi T, Miura N, Sameshima H, Koide T, Tanaka KA, Maruyama I
    • Journal Title

      Thromb Res

      Volume: 133(1) Issue: 1 Pages: 66-72

    • DOI

      10.1016/j.thromres.2013.10.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25670764
  • [Journal Article] Overexpression of receptor for advanced glycation end products and high-mobility group box 1 in human dental pulp inflammation.2014

    • Author(s)
      Tancharoen S, Tengrungsun T, Suddhasthira T, Kikuchi K, Vechvongvan N, Tokuda M, Maruyama I.
    • Journal Title

      Mediators Inflamm.

      Volume: 2014 Pages: 754069-754069

    • DOI

      10.1155/2014/754069

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670790
  • [Journal Article] Comparative evaluation of direct thrombin and factor Xa inhibitors with antiplatelet agents under flow and static conditions : an in vitro flow chamber model2014

    • Author(s)
      Hosokawa K, Ohnishi T, Sameshima H, Miura N, Koide T, Maruyama I, Tanaka KA
    • Journal Title

      PLoS One

      Volume: 9(1) Issue: 1 Pages: 86491-86491

    • DOI

      10.1371/journal.pone.0086491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25670764
  • [Journal Article] HMGB1 promotes the development of pulmonary arterial hypertension in rats.2014

    • Author(s)
      Sadamura-Takenaka Y, Ito T, Noma S, Oyama Y, Yamada S, Kawahara K, Inoue H, Maruyama I.
    • Journal Title

      PLoS One.

      Volume: 9 Issue: 7 Pages: e102482-e102482

    • DOI

      10.1371/journal.pone.0102482

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390402, KAKENHI-PROJECT-25293192, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26670793
  • [Journal Article] Hyaluronan protection of corneal endothelial cells against extracellular histones after phacoemulsification.2014

    • Author(s)
      Kawano H, Sakamoto T, Ito T, Miyata K, Hashiguchi T, Maruyama I.
    • Journal Title

      J Cataract Refract Surg

      Volume: 40 Issue: 11 Pages: 1885-93

    • DOI

      10.1016/j.jcrs.2014.07.026

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659765, KAKENHI-PROJECT-26670789, KAKENHI-PROJECT-26670790
  • [Journal Article] Toxic effects of extracellular histones and their neutralization by vitreous in retinal detachment2014

    • Author(s)
      Kawano H, Ito T, Yamada S, Hashiguchi T, Maruyama I, Hisatomi T, Nakamura M, Sakamoto T
    • Journal Title

      Lab Invest

      Volume: 94(5) Pages: 569-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670763
  • [Journal Article] Recombinant thrombomodulin protects mice against histone-induced lethal thromboembolism.2013

    • Author(s)
      Nakahara M, Ito T, et al.
    • Journal Title

      PLoS One

      Volume: 8(9) Issue: 9 Pages: 75961-75961

    • DOI

      10.1371/journal.pone.0075961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02424, KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659700, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25670763, KAKENHI-PROJECT-25670764
  • [Journal Article] Analysing responses to aspirin and clopidogrel by measuring platelet thrombus formation under arterial flow conditions2013

    • Author(s)
      Hosokawa K, Ohnishi T, Sameshima H, Miura N, Ito T, Koide T, Maruyama I
    • Journal Title

      Thromb Haemost

      Volume: 109(1) Issue: 01 Pages: 102-11

    • DOI

      10.1160/th12-06-0441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659798, KAKENHI-PROJECT-24659804
  • [Journal Article] Preventive effects of Morus alba L. anthocyanins on diabetes in Zucker diabetic fatty rats2013

    • Author(s)
      Sarikaphuti A, Nararatwanchai T, Hashiguchi T, Ito T, Thaworanunta S, Kikuchi K, Oyama Y, Maruyama I, Tancharoen S
    • Journal Title

      Exp Ther Med

      Volume: 6(3) Pages: 689-695

    • URL

      http://www.spandidos-publications.com/etm/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Journal Article] Saturated fatty acid palmitate induces extracellular release of histone H3 : a Possible mechanistic basis for high-fat diet-induced inflammation and thrombosis.2013

    • Author(s)
      Shrestha C, Ito T, et al.
    • Journal Title

      Biochemical and biophysical research communications

      Volume: 437(4) Issue: 4 Pages: 573-578

    • DOI

      10.1016/j.bbrc.2013.06.117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12F02424, KAKENHI-PROJECT-24659282, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25293132, KAKENHI-PROJECT-25670764
  • [Journal Article] Coagulation activity and white thrombus formation in the microminipig2013

    • Author(s)
      Miura N, Kawaguchi H, Nagasato T, Yamada T, Ito T, Izumi H, Sameshima H, Miyoshi N, Tanimoto A, Maruyama I
    • Journal Title

      In Vivo

      Volume: 27(3) Pages: 357-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Coagulation activity and white thrombus formation in the microminipig2013

    • Author(s)
      Miura N, Kawaguchi H, Nagasato T, Yamada T, Ito T, Izumi H, Shameshima H, Miyoshi N, Tanimoto A, Maruyama I
    • Journal Title

      In Vivo

      Volume: 27(3) Pages: 357-61

    • URL

      http://iv.iiarjournals.org

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Journal Article] Neutrophil elastase inhibitor improves survival rate after ischemia reperfusion injury caused by supravisceral aortic clamping in rats2013

    • Author(s)
      Fujimura N, Obara H, Suda K, Takeuchi H, Miyasho T, Kawasako K, Du W, Yamada S, Ono S, Matsumoto K, Matsuda S, Yagi H, Kitago M, Shinoda M, Itano O, Tanabe M, Sakamoto M, Maruyama I, Kitagawa Y
    • Journal Title

      J Surg Res

      Volume: 180(1) Issue: 1 Pages: 31-36

    • DOI

      10.1016/j.jss.2012.04.037

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23591875, KAKENHI-PROJECT-24591888
  • [Journal Article] Potential of the angiotensin receptor blockers (ARBs) telmisartan, Irbesartan, and candesartan for inhibiting the HMGB1/RAGE axis in prevention and acute treatment of stroke.2013

    • Author(s)
      Kikuchi K, Tancharoen S, Ito T, Morimoto-Yamashita Y, Miura N, Kawahara K, MaruyamaI, Murai Y, Tanaka E
    • Journal Title

      Int. Mol. Sci.

      Volume: 14 Issue: 9 Pages: 18899-18924

    • DOI

      10.3390/ijms140918899

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590269, KAKENHI-PROJECT-24390402, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25305032
  • [Journal Article] Immunohistochemical expression of thrombomodulin in vestibular schwannoma2013

    • Author(s)
      Yamahata H, Yunoue S, Tokimura H, Hanaya R, Hirano H, Tokudome M, Karki P, Yonezawa H, Sugata S, Kawahara K, Maruyama I, Arita K
    • Journal Title

      Brain Tumor Pathol

      Volume: 30(1) Issue: 1 Pages: 28-33

    • DOI

      10.1007/s10014-012-0095-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-24659804, KAKENHI-PROJECT-25305032
  • [Journal Article] Recombinant Thrombomodulin Protects Mice against Histone-Induced Lethal Thromboembolism2013

    • Author(s)
      Nakahara M, Ito T, Kawahara K, Yamamoto M, Nagasato T, Shrestha B, Yamada S, Miyauchi T, Higuchi K, Takenaka T, Yasuda T, Matsunaga A, Kakihana Y, Hashiguchi T, Kanmura Y, Maruyama I
    • Journal Title

      PLoS One

      Volume: 8(9)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670763
  • [Journal Article] Hemoadsorption of high-mobility group box chromosomal protein 1 using a column for large animals2013

    • Author(s)
      Nishiyama R, Shinoda M, Tanabe M, Oshima G, Takano K, Miyasho T, Fuchimoto Y, Yamada S, Inoue T, Shimada K, Suda K, Tanaka M, Hayashida T, Yagi H, Kitago M, Obara H, Itano O, Takeuchi H, Kawachi S, Maruyama I, Kitagawa Y
    • Journal Title

      Eur Surg Res

      Volume: 51(3-4) Issue: 3-4 Pages: 181-90

    • DOI

      10.1159/000357563

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23591875, KAKENHI-PROJECT-24591888, KAKENHI-PROJECT-24659804
  • [Journal Article] Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction2012

    • Author(s)
      Hashimoto T, Ishii J, Kitagawa F, Yamada S, Hattori K, Okumura M, Naruse H, Motoyama S, Matsui S, Tanaka I, Izawa H, Maruyama I, Nomura M, Ozaki Y
    • Journal Title

      Atherosclerosis

      Volume: 221(2) Issue: 2 Pages: 490-5

    • DOI

      10.1016/j.atherosclerosis.2012.01.040

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Efficacy of MK615 for the treatment of patients with liver disorders2012

    • Author(s)
      Hokari A, Ishikawa T, Tajiri H, Matsuda T, Ishii O, Matsumoto N, Okuse C, Takahashi H, Kurihara T, Kawahara K, Maruyama I, Zeniya M
    • Journal Title

      World J Gastroenterol

      Volume: 18(31) Issue: 31 Pages: 4118-26

    • DOI

      10.3748/wjg.v18.i31.4118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Journal Article] Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction2012

    • Author(s)
      Hashimoto T, Maruyama I, Ozaki Y., et al
    • Journal Title

      Atherosclerosis

      Volume: 221 Pages: 490-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Paucity of CD34-positive cells and increased expression of high-mobility group box 1 in coronary thrombus with type 2 diabetes mellitus.2012

    • Author(s)
      Yamashita A, Nishihira K, Matsuura Y, Ito T, Kawahara K, Hatakeyama K, Hashiguchi T, Maruyama I, Yagi H, Matsumoto M, Fujimura Y, Kitamura K, Shibata Y, Asada Y.
    • Journal Title

      Atherosclerosis.

      Volume: 224 Issue: 2 Pages: 511-514

    • DOI

      10.1016/j.atherosclerosis.2012.07.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591069, KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23591425, KAKENHI-PROJECT-23790410, KAKENHI-PROJECT-24659804
  • [Journal Article] Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice2012

    • Author(s)
      Kohno M, Watanabe M, Izumi Y, Tasaka S, Kitagawa Y, Maruyama I, Kobayashi K
    • Journal Title

      Thorac Cardiovasc Surg

      Volume: 60(2) Issue: 02 Pages: 124-30

    • DOI

      10.1055/s-0030-1271011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims : A pilot study2012

    • Author(s)
      Oda Y, Maruyama I, Maekawa T, et al
    • Journal Title

      Resuscitation

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims2012

    • Author(s)
      Oda Y, Tsuruta R, Fujita M, Kaneda K, Kawamura Y, Izumi T, Kasaoka S, Maruyama I., Maekawa T
    • Journal Title

      A pilot study

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Granulocyte and monocyte adsorption apheresis as an effective treatment for Reiter disease2012

    • Author(s)
      Yoshifuku A, Oyama K, Ibusuki A, Kawasaki M, Sakanoue M, Matsushita S, Kawai K, Kawahara K, Maruyama I, Kanekura T
    • Journal Title

      Clin Exp Dermatol

      Volume: 37 Pages: 241-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Secondary prevention of stroke : Pleiotropic effects of optimal oral pharmacotherapy2012

    • Author(s)
      Kikuchi K, Kawahara K, Miura N, Ito T, Morimoto Y, Tancharoen S, Takeshige N, Uchikado H, Sakamoto R, Miyagi N, Kikuchi C, Iida N, Shiomi N, Kuramoto T, Hirohata M, Maruyama I, Morioka M, Tanaka E
    • Journal Title

      Exp Ther Med

      Volume: 4(1) Pages: 3-7

    • URL

      http://www.spandidos-publications.com/etm/

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Journal Article] Role of high mobility group box chromosomal protein 1 in ischemia-reperfusion injury in the rat small intestine2012

    • Author(s)
      Kojima M, Maruyama I, Kitagawa Y, et al
    • Journal Title

      J Surg Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Increased plasma levels of high mobility group box 1 in patients with acute liver failure2012

    • Author(s)
      Oshima G, Shinoda M, Tanabe M, Ebinuma H, Nishiyama R, Takano K, Yamada S, Miyasho T, Masugi Y, Matsuda S, Suda K, Fukunaga K, Matsubara K, Hibi T, Yagi H, Hayashida T, Yamagishi Y, Obara H, Itano O, Takeuchi H, Kawachi S, Saito H, Hibi T, Maruyama I, Kitagawa Y
    • Journal Title

      Eur Surg Res

      Volume: 48(3) Issue: 3 Pages: 154-62

    • DOI

      10.1159/000338363

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23591875, KAKENHI-PROJECT-23791498, KAKENHI-PROJECT-24591888
  • [Journal Article] MK615, a Prunus mume Steb.Et Zucc (Ume) extract, attenuates the growth of A375 melanoma cells by inhibiting the ERK1/2-Id-1 pathway2012

    • Author(s)
      Tada K
    • Journal Title

      Phytother Res

      Volume: (in press) Issue: 6 Pages: 833-838

    • DOI

      10.1002/ptr.3645

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591438, KAKENHI-PROJECT-22390179, KAKENHI-PROJECT-24659804
  • [Journal Article] Role of high mobility group box chromosomal protein 1 in ischemia-reperfusion injury in the rat small intestine2012

    • Author(s)
      Kojima M, Tanabe M, Shinoda M, Yamada S, Miyasho T, Suda K, Hibi T, Obara H, Itano O, Kawachi S, Kitajima M, Maruyama I, Kitagawa Y
    • Journal Title

      J Surg Res

      Volume: 178(1) Issue: 1 Pages: 466-71

    • DOI

      10.1016/j.jss.2012.01.044

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23591875, KAKENHI-PROJECT-24591888, KAKENHI-PROJECT-24659798
  • [Journal Article] Role of high mobility group box chromosomal protein 1 in ischemia-reperfusion injury in the rat small intestine2012

    • Author(s)
      Kojima M, Maruyama I, Kitagawa Y, et al
    • Journal Title

      J Surg Res

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Granulocyte and monocyte adsorption apheresis as an effective treatment for Reiter disease2012

    • Author(s)
      Yoshifuku A, Oyama K, Ibusuki A, Kawasaki M, Sakanoue M, Matsushita S, Kawai K, Kawahara K, Maruyama I, Kanekura T
    • Journal Title

      Clin Exp Dermatol

      Volume: 37(3) Issue: 3 Pages: 241-4

    • DOI

      10.1111/j.1365-2230.2011.04181.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Journal Article] Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice2012

    • Author(s)
      Kohno M, Watanabe M, Izumi Y, Tasaka S, Kitagawa Y, Maruyama I, Kobayashi K.
    • Journal Title

      Thorac Cardiovasc Surg

      Volume: 60(2) Pages: 124-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Paucity of CD34-positive cells and increased expression of high-mobility group box 1 in coronary thrombus with type 2 diabetes mellitus2012

    • Author(s)
      Yamashita A, Nishihira K, Matsuura Y, Ito T, Kawahara K, Hatakeyama K, Hashiguchi T, Maruyama I, Yagi H, Matsumoto M, Fujimura Y, Kitamura K, Shibata Y, Asada Y.
    • Journal Title

      Atherosclerosis

      Volume: 224(2) Pages: 511-514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] Immunohistochemical expression of thrombomodulin in vestibular schwannoma2012

    • Author(s)
      Yamahata H, Yunoue S, Tokimura H, Hanaya R, Hirano H, Tokudome M, Karki P, Yonezawa H, Sugata S, Kawahara KI, Maruyama I, Arita K
    • Journal Title

      Brain Tumor Pathol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] MK615, a Prunus mume Steb. Et Zucc ('Ume') extract, attenuates the growth of A375 melanoma cells by inhibiting the ERK1/2-Id-1 pathway2012

    • Author(s)
      Tada K, Kawahara K, Matsushita S, Hashiguchi T, Maruyama I, Kanekura T
    • Journal Title

      Phytother Res

      Volume: 26(6) Pages: 833-838

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims : A pilot study2012

    • Author(s)
      Oda Y Maruyama I, Maekawa T, et al
    • Journal Title

      Resuscitation

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction2012

    • Author(s)
      Hashimoto T, Ishii J, Kitagawa F, Yamada S, Hattori K, Okumura M, Naruse H, Motoyama S, Matsui S, Tanaka I, Izawa H, Maruyama I, Nomura M, Ozaki Y.
    • Journal Title

      Atherosclerosis

      Volume: 221(2) Pages: 490-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Role of high mobility group box chromosomal protein 1 in ischemia-reperfusion injury in the rat small intestine2012

    • Author(s)
      Kojima M, Tanabe M, Shinoda M, Yamada S, Miyasho T, Suda K, Hibi T, Obara H, Itano O, Kawachi S, Kitajima M, Maruyama I, Kitagawa Y.
    • Journal Title

      J Surg Res

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Prediction of the neurological outcome with intrathecal high mobility group box 1 and S100B in cardiac arrest victims : a pilot study2012

    • Author(s)
      Oda Y, Tsuruta R, Fujita M, Kaneda K, Kawamura Y, Izumi T, Kasaoka S, Maruyama I, Maekawa T
    • Journal Title

      Resuscitation

      Volume: 83(8) Issue: 8 Pages: 1006-12

    • DOI

      10.1016/j.resuscitation.2012.01.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Circulating high-mobility group box 1 and cardiovascular mortality in unstable angina and non-ST-segment elevation myocardial infarction2012

    • Author(s)
      Hashimoto T, Maruyama I, Ozaki Y., et al
    • Journal Title

      Atherosclerosis

      Volume: 221 Pages: 490-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Valproic acid increases susceptibility to endotoxin shock through enhanced release o f high-mobility group box 12011

    • Author(s)
      Sugiura S, Ishihara Y, Komatsu T, Hagiwara M, Tanigawa N, Kato Y, Mizutani H, Kawahara K, Maruyama I, Noguchi T, Matsushita K.
    • Journal Title

      Shock 2011

      Volume: 36(5) Pages: 494-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation2011

    • Author(s)
      Ito T, Maruyama I.
    • Journal Title

      J Thromb Haemost

      Volume: 9 Pages: 168-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890166
  • [Journal Article] Valproic acid increases susceptibility to endotoxin shock through enhanced release of HMGB12011

    • Author(s)
      Sugiura, et al
    • Journal Title

      Shock

      Volume: 36(5) Issue: 5 Pages: 494-500

    • DOI

      10.1097/shk.0b013e31822f7e58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J09815, KAKENHI-PROJECT-21659436, KAKENHI-PROJECT-22390354, KAKENHI-PROJECT-22592322, KAKENHI-PROJECT-23390412
  • [Journal Article] Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis2011

    • Author(s)
      Ebina M, Maruyama I, Nukiwa T, et al
    • Journal Title

      Pulm Med

      Volume: 2011 Pages: 916486-916486

    • NAID

      120005761658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice2011

    • Author(s)
      Kohno M, Maruyama I, Kobayashi K., et al
    • Journal Title

      Thorac Cardiovasc Surg

      Volume: 60 Pages: 124-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Quantitative peptidomic analysis by a newly developed one-step direct transfer technology without depletion of major blood proteins: its potential utility for monitoring of pathophysiological status in pregnancy-induced hypertension2011

    • Author(s)
      Araki Y, Nonaka D, Tajima A, Maruyama M, Nitto T, Ishikawa H, Yoshitake H, Yoshida E, Kuronaka N, Asada K, Yanagida M, Nojima M, Yoshida K, Takamori K, Hashiguchi T, Maruyama I, Lee LJ, Tanaka K
    • Journal Title

      Proteomics.

      Volume: 11(13) Pages: 2727-2737

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] Valproic acid increases susceptibility to endotoxin shock through enhanced release of high-mobility group box 12011

    • Author(s)
      Sugiura S, Ishihara Y, Komatsu T, Hagiwara M, Tanigawa N, Kato Y, Mizutani H, Kawahara K, Maruyama I, Noguchi T, Matsushita K
    • Journal Title

      Shock

      Volume: 36 Pages: 494-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation. J2011

    • Author(s)
      Ito T, Maruyama I
    • Journal Title

      Thromb Haemost

      Volume: 9 Pages: 168-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation2011

    • Author(s)
      Takashi Ito & Ikuro Maruyama.
    • Journal Title

      Journal of Thrombosis and Haemostasis

      Volume: 9 Pages: 168-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] NSAIDs inhibit neovascularization of chroid through HO-1-dpendency pathway2011

    • Author(s)
      Yoshinaga N, Arimura N, Otsuka H, Kawahara K, Hashiguchi T, Maruyama I
    • Journal Title

      Sakamoto T. Lab Invest

      Volume: 91 Pages: 1277-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] 新規DIC 治療薬トロンボモジュリン製剤の作用機序2011

    • Author(s)
      伊藤隆史, 丸山征郎
    • Journal Title

      臨床血液

      Volume: 52巻 Pages: 356-360

    • NAID

      130004501537

    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation J2011

    • Author(s)
      Ito T, Maruyama I
    • Journal Title

      Thromb Haemost

      Volume: 9 Pages: 168-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] 新規DIC治療薬トロンボモジュリン製剤の作用機序2011

    • Author(s)
      伊藤隆史、丸山征郎
    • Journal Title

      臨床血液

      Volume: 52 Pages: 356-360

    • NAID

      130004501537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890166
  • [Journal Article] 新規DIC治療薬トロンボモジュリン製剤の作用機序2011

    • Author(s)
      伊藤隆史・丸山征郎
    • Journal Title

      臨床血液

      Volume: 第52巻6号 Pages: 356-360

    • NAID

      130004501537

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890166
  • [Journal Article] Improvement of Blood Compatibility on Polysulfone-Polyvinylpyrrolidone Blend Films as a Model Membrane of Dialyzer by Physical Adsorption of Recombinant Soluble Human Thrombomodulin (ART-123).2011

    • Author(s)
      Omichi M, Matsusaki M, Maruyama I, Akashi M.
    • Journal Title

      J Biomater Sci Polym Ed.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659327
  • [Journal Article] NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway2011

    • Author(s)
      Yoshinaga N, Arimura N, Otsuka H, Kawahara K, Hashiguchi T, Maruyama I, Sakamoto T.
    • Journal Title

      Lab Invest

      Volume: 91(9) Issue: 9 Pages: 1277-1290

    • DOI

      10.1038/labinvest.2011.101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450, KAKENHI-PROJECT-22390179
  • [Journal Article] NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway2011

    • Author(s)
      Yoshinaga N, Arimura N, Otsuka H, Kawahara K, Hashiguchi T, Maruyama I, Sakamoto T
    • Journal Title

      Lab Invest

      Volume: 91(9) Pages: 1277-1290

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] Gradualincrease of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis2011

    • Author(s)
      Ebina M, Maruyama I, Nukiwa T, et al
    • Journal Title

      Pulm Med

      Volume: 2011 Pages: 916486-916486

    • NAID

      120005761658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Improvement of Blood Compatibility on Polysulfone-Polyvinylpyrrolidone Blend Films as a Model Membrane of Dialyzer by Physical Adsorption of Recombinant Soluble Human Thrombomodulin(ART-123).2011

    • Author(s)
      Omichi M, Matsusaki M, Maruyama I, Akashi M.
    • Journal Title

      J Biomater Sci Polym Ed.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Gradual increase of high mobility group protein b1 in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis2011

    • Author(s)
      Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Ohkouchi S, Tamada T, Nishimura H, Ishizaka A, Maruyama I, Okada Y, Takashi K, Nukiwa T.
    • Journal Title

      Pulm Med

      Volume: 2011 Pages: 916486-916486

    • NAID

      120005761658

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Valproic acid increases susceptibility to endotoxin shock through enhanced release o f high-mobility group box 12011

    • Author(s)
      Sugiura S, Maruyama I, Matsushita K., et al
    • Journal Title

      Shock

      Volume: 36(5) Pages: 494-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation2011

    • Author(s)
      Ito T, Maruyama I.
    • Journal Title

      J Thromb Haemost

      Volume: 1 Pages: 168-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] 新規DIC治療薬トロンボモジュリン製剤の作用機序2011

    • Author(s)
      伊藤隆史、丸山征郎
    • Journal Title

      臨床血液

      Volume: 52 Pages: 356-360

    • NAID

      130004501537

    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Gradual increase of high mobility group protein B 1 (HMGB1) in the lungs after the onset of acute exacerbation of idiopathic pulmonary fibrosis2011

    • Author(s)
      Ebina M, Taniguchi H, Miyasho T, Yamada S, Shibata N, Ohta H, Hisata S, Hirota N, Nishimura H, Ishizaka A, Maruyama I, Takashi K, Nukiwa T
    • Journal Title

      Pulmonary Med

      Volume: 916486 Pages: 1-9

    • DOI

      10.1155/2011/916486

    • NAID

      120003072907

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390164, KAKENHI-PROJECT-23390412
  • [Journal Article] Valproic acid increases susceptibilty to endotoxin shock through enhanced release of high-mobility group box 12011

    • Author(s)
      Sugiura S, Maruyama I, Matsushita K, et al
    • Journal Title

      Shock

      Volume: 36(5) Pages: 494-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Thrombomodulin : protectorate God of the vasculature in thrombosis and inflammation2011

    • Author(s)
      Ito T, Maruyama I
    • Journal Title

      J Thromb Haemost

      Volume: Suppl 1 Pages: 168-73

    • DOI

      10.1111/j.1538-7836.2011.04319.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390412, KAKENHI-PROJECT-23890166
  • [Journal Article] Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice2011

    • Author(s)
      Kohno M, Maruyama I, Kobayashi K, et al
    • Journal Title

      Thorac Cardiovasc Surg

      Volume: 60 Pages: 124-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659491
  • [Journal Article] Neutrophil elastase inhibitor improves survival of rats with clinically relevant sepsis.2010

    • Author(s)
      Suda K, Takeuchi H, Hagiwara T, Miyasho T, Okamoto M, Kawasako K, Yamada S, Suganuma K, Wada N, Saikawa Y, Fukunaga K, Funakoshi Y, Hashimoto S, Yokota H, Maruyama I, Ishizaka A, Kitagawa Y.
    • Journal Title

      Shock. 33(5)

      Pages: 526-531

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.2010

    • Author(s)
      Otsuka H, Arimura N, Sonoda S, Nakamura M, Hashiguchi T, Maruyama I, Nakao S, Hafezi-Moghadam A, Sakamoto T.
    • Journal Title

      Am J Pathol. 177(5)

      Pages: 2268-2277

    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Protective effect of high-mobility group box 1 blockade on acute liver failure in rats.2010

    • Author(s)
      Takano K, Maruyama I, Kitagawa Y., et al.
    • Journal Title

      Shock 34(6)

      Pages: 573-579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] High mobility group box 1 is upregulated after spinal cord injury and is associated with neuronal cell apoptosis.2010

    • Author(s)
      Kawabata H, Setoguchi T, Yone K, Souda M, Yoshida H, Kawahara K, Maruyama I, Komiya S.
    • Journal Title

      Spine (Phila Pa 1976). 35(11)

      Pages: 1109-1115

    • NAID

      10027252218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] B cell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes.2010

    • Author(s)
      Hashiguchi T*, Shrestha B*, Ito T*, Miura N* (*Equal contribution), Takenouchi K, Oyama Y, Kawahara K, Tancharoen S, Ki-i Y, Arimura N, Yoshinaga N, Noma S, Shrestha C, Nitanda T, Kitajima S, Arimura K, Sato M, Sakamoto T, Maruyama I
    • Journal Title

      J Immunol 184

      Pages: 4819-4826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] High mobility group box 1 is upregulated after spinal cord injury and is associated with neuronal cell apoptosis2010

    • Author(s)
      Kawabata H, Setoguchi T, Yone K, Souda M, Yoshida H, Kawahara K, Maruyama I, Komiya S
    • Journal Title

      Spine(Phila Pa 1976)

      Volume: 35 Pages: 1109-15

    • NAID

      10027252218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] ER signaling is activated to protect human HaCaT keratinocytes from ER stress induced by environmental doses of UVB2010

    • Author(s)
      Mera K, Kawahara K, Tada K, Kawai K, Hashiguchi T, Maruyama I, Kanekura T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 397 Pages: 350-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Hemoperfusion with a high-mobility group box 1 adsorption column can prevent the occurrence of hepatic ischemia-reperfusion injury in rats.2010

    • Author(s)
      Yamamoto T, Ono T, Ito T, Yamanoi A, Maruyama I, Tanaka T.
    • Journal Title

      Crit Care Med. 38(3)

      Pages: 879-885

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] The diagnostic value of endothelial function as a potential sensor of fatigue in health.2010

    • Author(s)
      Ohno Y, Hashiguchi T, Maenosono R, Yamashita H, Taira Y, Minowa K, Yamashita Y, Kato Y, Kawahara K, Maruyama I
    • Journal Title

      Vasc Health Risk Manag 6

      Pages: 135-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment2010

    • Author(s)
      Otsuka H, Arimura N, Sonoda S, Nakamura M, Hashiguchi T, Maruyama I, Nakao S, Hafezi-Moghadam A, Sakamoto T
    • Journal Title

      Am J Pathol

      Volume: 177 (5) Pages: 2268-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] High-mobility group box 1 is involved in the initial events of early loss of transplanted islets in mice.2010

    • Author(s)
      Matsuoka N, Itoh T, Watarai H, Sekine-Kondo E, Nagata N, Okamoto K, Mera T, Yamamoto H, Yamada S, Maruyama I, Taniguchi M, Yasunami Y.
    • Journal Title

      J Clin Invest. 120(3)

      Pages: 735-743

    • NAID

      120002142757

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Hyperglycemia enhances excessive superoxide anion radical generation, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats.2010

    • Author(s)
      Tsuruta R, Fujita M, Ono T, Koda Y, Koga Y, Yamamoto T, Nanba M, Shitara M, Kasaoka S, Maruyama I, Yuasa M, Maekawa T.
    • Journal Title

      Brain Res. 1309

      Pages: 155-163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Spherical sulfated cellulose adsorbs high-mobility-group box chromosomal protein 1 in vitro and in vivo.2010

    • Author(s)
      Suda K, Takeuchi H, Maruyama I, Kitagawa Y, et al.
    • Journal Title

      ASAIO J.

      Volume: 56(3) Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659327
  • [Journal Article] High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy2010

    • Author(s)
      Oyama Y, Hashiguchi T, Taniguchi N, Tancharoen S, Uchimura T, Biswas KK, Kawahara K, Nitanda T, Umekita Y, Lotz M, Maruyama I
    • Journal Title

      Lab Invest

      Volume: 90 Pages: 853-66

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Advanced malignant melanoma responds to Prunus mume Sieb. Et Zucc (Ume) extract: Case report and in vitro study.2010

    • Author(s)
      Matsushita S, Tada KI, Kawahara KI, Kawai K, Hashiguchi T, Maruyama I, Kanekura T
    • Journal Title

      Exp Ther Med

      Volume: 1(4) Pages: 569-574

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy.2010

    • Author(s)
      Oyama Y, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Lab Invest. 90(6)

      Pages: 853-866

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Involvement of the endocannabinoid system in periodontal healing2010

    • Author(s)
      Kozono S, Matsuyama T, Biwasa KK, Kawahara K, Nakajima Y, Yoshimoto T, Yonamine Y, Kadomatsu H, Tancharoen S, Hashiguchi T, Noguchi K, Maruyama I
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 394 Pages: 928-33

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Spherical sulfated cellulose adsorbs high-mobility-group box chromosomal protein 1 in vitro and in vivo.2010

    • Author(s)
      Suda K, Takeuchi H, Maruyama I, Kitagawa Y, et al.
    • Journal Title

      ASAIO J. 56(3)

      Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.2010

    • Author(s)
      Otsuka H, Arimura N, Sonoda S, Nakamura M, Hashiguchi T, Maruyama I, Nakao S, Hafbzi-Moghadam A, Sakamoto T.
    • Journal Title

      Am J Pathol.

      Volume: 177(5) Pages: 2268-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Spherical sulfated cellulose adsorbs high-mobility-group box chromosomal protein 1 in vitro and in vivo.2010

    • Author(s)
      Suda K, Takeuchi H, Maruyama I, Kitagawa Y, et al.
    • Journal Title

      ASAIO J.

      Volume: 56(3) Pages: 210-214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] The diagnostic value of endothelial function as a potential sensor of fatigue in health2010

    • Author(s)
      Ohno Y, Hashiguchi T, Maenosono R, Yamashita H, Taira Y, Minowa K, Yamashita Y, Kato Y, Kawahara K, Maruyama I
    • Journal Title

      Vasc Health Risk Manag

      Volume: 24 Pages: 135-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] ER signaling is activated to protect human HaCaT keratinocytes from ER stress induced by environmental doses of UVB2010

    • Author(s)
      Mera K, Kawahara K, Tada K, Kawai K, Hashiguchi T, Maruyama I, Kanekura T
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 397(2) Pages: 350-354

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Journal Article] Protective effect of high mobility group box 1 blockade on acute liver failure in rats.2010

    • Author(s)
      Takano K, Maruyama I, Kitagawa Y, et al.
    • Journal Title

      Shock

      Volume: 34(6) Pages: 573-579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] B Cell-Derived Vascular Endothelial Growth Factor A Promotes Lymphangiogenesis and High Endothelial Venule Expansion in Lymph Nodes2010

    • Author(s)
      Shrestha B, Hashiguchi T, Ito T, Miura N, Takenouchi K, Oyama Y, Kawahara K, Tancharoen S, Ki-I Y, Arimura N, Yoshinaga N, Noma S, Shrestha C, Nitanda T, Kitajima S, Arimura K, Sato M, Sakamoto T, Maruyama I
    • Journal Title

      J Immunol

      Volume: 184 Pages: 4819-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Bcell-derived vascular endothelial growth factor A promotes lymphangiogenesis and high endothelial venule expansion in lymph nodes.2010

    • Author(s)
      Shrestha B, Hashiguchi T, Ito T, Miura N, Takenouchi K, Oyama Y, Kawahara K, Tancharoen S, Ki-I Y, Arimura N, Yoshinaga N, Noma S, Shrestha C, Nitanda T, Kitajima S, Arimura K, Sato M, Sakamoto T, Maruyama I.
    • Journal Title

      J Immunol.

      Volume: 184(9) Pages: 4819-4826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Protective effect of high-mobility group box 1 blockade on acute liver failure in rats.2010

    • Author(s)
      Takano K, Maruyama I, Kitagawa Y., et al.
    • Journal Title

      Shock

      Volume: 34(6) Pages: 573-579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659327
  • [Journal Article] Edaravone : a new therapeutic approach for the treatment of acute stroke2010

    • Author(s)
      Kikuchi K, Kawahara K, Miyagi N, Uchikado H, Kuramoto T, Morimoto Y, Tancharoen S, Miura N, Takenouchi K, Oyama Y, Shrestha B, Matsuda F, Yoshida Y, Arimura S, Mera K, Tada K, Yoshinaga N, Maenosono R, Ohno Y, Hashiguchi T, Maruyama I, Shigemori M
    • Journal Title

      Med Hypotheses

      Volume: 75 Pages: 583-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy2010

    • Author(s)
      Oyama Y, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Lab Invest (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Green tea extract supplement inhibition of HMGB1 release in rats exposed to cigarette smoke2010

    • Author(s)
      Saiwichai T, Sangalangkarn V, Kawahara K, Oyama Y, Chaichalotornkul S, Narkpinit S, Harnyuttanakorn P, Singhasivanon P, Maruyama I, Tancharoen S
    • Journal Title

      Southeast Asian J Trop Med Public Health

      Volume: 41 Pages: 250-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] 1, 5-Anhydroglucitol attenuates cytokine release and protects mice with type 2 diabetes from inflammatory reactions2010

    • Author(s)
      Meng X, Tancharoen S, Kawahara KI, Nawa Y, Taniguchi S, Hashiguchi T, Maruyama I
    • Journal Title

      Int J Immunopathol Pharmacol

      Volume: 23 Pages: 105-19

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Hyperoxia suppresses excessive superoxide anion radical generation in blood, oxidative stress, early inflammation, and endothelial injury in forebrain ischemia/reperfusion rats : laboratory study.2010

    • Author(s)
      Fujita M, Tsuruta R, Kaneko T, Otsuka Y, Kutsuna S, Izumi T, Aoki T, Shitara M, Kasaoka S, Maruyama I, Yuasa M, Maekawa T.
    • Journal Title

      Shock. 34(3)

      Pages: 299-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment2010

    • Author(s)
      Otsuka H, Arimura N, Sonoda S, Nakamura M, Hashiguchi T, Maruyama I, Nakao S, Hafezi-Moghadam A, Sakamoto T.
    • Journal Title

      Am J Pathol

      Volume: 177(5) Issue: 5 Pages: 2268-2277

    • DOI

      10.2353/ajpath.2010.100134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Minocycline attenuates both OGD-induced HMGB1 release and HMGB1induced cell death in ischemic neuronal injury in PC12 cells.-2009

    • Author(s)
      Kikuchi K, Kawahara K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Biochem Biophys Res Commun. 385(2)

      Pages: 132-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009

    • Author(s)
      Araya N, Arimura H, Kawahara K, Yagishita N, Ishida J, Fujii R, Aratani S, Fujita H, Sato T, Yamano Y, Higuchi I, Osame M, Nishioka K, Fukamizu A, Arimura K, Maruyama I, Nakajima T.
    • Journal Title

      Int J Mol Med

      Volume: 24 Issue: 05 Pages: 605-611

    • DOI

      10.3892/ijmm_00000271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-23659176
  • [Journal Article] Nucleophosmin may act as an alarmin : implications for severe sepsis2009

    • Author(s)
      Nawa Y, Kawahara K, Tancharoen S, Meng X, Sameshima H, Ito T, Masuda Y, Imaizumi H, Hashiguchi T, Maruyama I
    • Journal Title

      J Leukoc Biol

      Volume: 86 Pages: 645-53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Diagnostic value of serum peptidome analyses for protease activated pathological conditions beyond cancer diagnosis.2009

    • Author(s)
      Hashiguchi T, Tanaka K, Lee LJ, Sasaki K, Natsugoe S, Kawahara K, Arimura K, Maruyama I
    • Journal Title

      Med Hypotheses 73

      Pages: 760-763

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment2009

    • Author(s)
      Arimura N, Ki-i Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I.
    • Journal Title

      Lab Invest 89(3)

      Pages: 278-289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells2009

    • Author(s)
      Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I
    • Journal Title

      J Pharmacol Exp Ther

      Volume: 329 Pages: 865-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.2009

    • Author(s)
      Arimura N, Ki-i Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I
    • Journal Title

      Lab Invest 89

      Pages: 278-289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] An elevated value of high mobility group box 1 is a potential marker for poor response to high-dose of intravenous immunoglobulin treatment in patients with Kawasaki syndrome.2009

    • Author(s)
      Eguchi T, Nomura Y, Hashiguchi T, Masuda K, Arata M, Hazeki D, Ueno K, Nishi J, Kawano Y, Maruyama I.
    • Journal Title

      Pediatr Infect Dis J. 28(4)

      Pages: 339-341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] High-mobility group box 1 protein in CSF of patients with subarachnoid hemorrhage.2009

    • Author(s)
      Nakahara T, Tsuruta R, Kaneko T, Yamashita S, Fujita M, Kasaoka S, Hashiguchi T, Suzuki M, Maruyama I, Maekawa T.
    • Journal Title

      Neurocrit Care. 11(3)

      Pages: 362-368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha2009

    • Author(s)
      Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
    • Journal Title

      Arthritis Rheum

      Volume: 60 Issue: 1 Pages: 63-72

    • DOI

      10.1002/art.24178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] Vitreous mediators after intravitreal bevacizumab or triamcinolone acetonide in eyes with proliferative diabetic retinopathy.2009

    • Author(s)
      Arimura N, Otsuka H, Yamakiri K, Sonoda Y, Nakao S, Noda Y, Hashiguchi T, Maruyama I, Sakamoto T
    • Journal Title

      Ophthalmology 116

      Pages: 921-926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Increased Prevalence of Group A b-hemolytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test2009

    • Author(s)
      中島利博、八木下尚子、上昌広、丸山征郎、山野嘉久, 他12名
    • Journal Title

      Molecular Medicine Reports 1(6)

      Pages: 869-874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] Increased Prevalence of Group A b-hemolnytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test.2009

    • Author(s)
      中島利博、八木下尚子、丸山征郎、山野嘉久他13名
    • Journal Title

      Molecular Medicine Reports 1(6)

      Pages: 869-874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059033
  • [Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment2009

    • Author(s)
      Arimura N, Ki-i Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I.
    • Journal Title

      Lab Invest

      Volume: 89(3) Pages: 278-289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Xanthine oxidase is one of the major sources of superoxide anion radicals in blood after reperfusion in rats with forebrain ischemia/reperfusion.2009

    • Author(s)
      Ono T, Tsuruta R, Fujita M, Aki HS, Kutsuna S, Kawamura Y, Wakatsuki J, Aoki T, Kobayashi C, Kasaoka S, Maruyama I, Yuasa M, Maekawa T.
    • Journal Title

      Brain Res. 1305

      Pages: 158-167

    • NAID

      120002220601

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Role of Kenae/CCDC125 in cell motility through the deregulation of RhoGTPase2009

    • Author(s)
      Araya N, Arimura H, Kawahara K, Yagishita N, Ishida J, Fujii R, Aratani S, Fujita H, Sato T, Yamano Y, Higuchi I, Osame M, Nishioka K, Fukamizu A, Arimura K, Maruyama I, Nakajima T
    • Journal Title

      Int J Mol Med

      Volume: 24 Pages: 605-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Mechanism of HMGB1 release inhibition from RAW264.7 cells by oleanolic acid in Prunus mume Sieb. et Zucc2009

    • Author(s)
      Kawahara K, Hashiguchi T, Masuda K, Saniabadi AR, Kikuchi K, Tancharoen S, Ito T, Miura N, Morimoto Y, Biswas KK, Nawa Y, Meng X, Oyama Y, Takenouchi K, Shrestha B, Sameshima H, Shimizu T, Adachi T, Adachi M, Maruyama I
    • Journal Title

      Int J Mol Med

      Volume: 23 Pages: 615-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.2009

    • Author(s)
      Kikuchi K, Kawahara K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      J Pharmacol Exp Ther. 329(3)

      Pages: 865-874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Activation of synoviolin promoter in rheumatoid synovial cells by a novel transcription complex of interleukin enhancer binding factor 3 and GA binding protein alpha.2009

    • Author(s)
      Izumi T, Fujii R, Izumi T, Nakazawa M, Yagishita N, Tsuchimochi K, Yamano Y, Sato T, Fujita H, Aratani S, Araya N, Azakami K, Hasegawa D, Kasaoka S, Tsuruta R, Yokouti M, Ijiri K, Beppu M, Maruyama I, Nishioka K, Maekawa T, Komiya S, Nakajima T
    • Journal Title

      Arthritis Rheum. 60(1)

      Pages: 63-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] Vitreous mediators after intravitreal bevacizumab or triamcinolone acetonide in eyes with proliferative diabetic retinopathy2009

    • Author(s)
      Arimura N, Ohtsuka H, Yamakiri K, Sonoda Y, Nakao S, Noda Y, Hashiguchi T, Maruyama I, Sakamoto T.
    • Journal Title

      Ophthalmology 116(5)

      Pages: 921-926

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.2009

    • Author(s)
      Arimura N, Ki-i Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I
    • Journal Title

      Lab Invest. 89(3)

      Pages: 278-289

    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] MK615 attenuates Porphyromonas gingivalis lipopolysaccharide-induced pro-inflammatory cytokine release via MAPK inactivation in murine macrophage-like RAW264.7 cells2009

    • Author(s)
      Morimoto Y, Kikuchi K, Ito T, Tokuda M, Matsuyama T, Noma S, Hashiguchi T, Torii M, Maruyama I, Kawahara K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 389 Pages: 90-94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Attenuation of LPS-induced iNOS expression by 1, 5-anhydro-d-fructose2009

    • Author(s)
      Meng X, Kawahara K, Matsushita K, Nawa Y, Shrestha B, Kikuchi K, Sameshima H, Hashiguchi T, Maruyama I
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 387 Pages: 42-46

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390483
  • [Journal Article] Minocycline attenuates both OGD-induced HMGB1 release and HMGBlinduced cell death in ischemic neuronal injury in PC12 cells.2009

    • Author(s)
      Kikuchi K, Kawahara K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Biochem Biophys Res Commun. 385(2)

      Pages: 132-136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells2009

    • Author(s)
      Kikuchi K, Kawahara K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      J Pharmacol Exp Ther. 329(3)

      Pages: 865-74

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Intraocular expression and release of high-mobility group box 1 protein in retinal detachment.2009

    • Author(s)
      Arimura N, Ki-i Y, Hashiguchi T, Kawahara K, Biswas KK, Nakamura M, Sonoda Y, Yamakiri K, Okubo A, Sakamoto T, Maruyama I.
    • Journal Title

      Lab Invest. 89(3)

      Pages: 278-289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] Increased Prevalence of Group A b-hemolytic Streptococcus Among Ethnic Population in Kyrgyzstan Defined by Rapid Antigen Detection Test.2009

    • Author(s)
      中島利博、八木下尚子、丸山征郎、山野嘉久他13名
    • Journal Title

      Molecular Medicine Reports 1(6)

      Pages: 869-874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013045
  • [Journal Article] Elevation of jugular venous superoxide anion radical is associated with early inflammation, oxidative stress, and endothelial injury in forebrain ischemia-reperfusion rats.2009

    • Author(s)
      Aki HS, Fujita M, Yamashita S, Fujimoto K, Kumagai K, Tsuruta R, Kasaoka S, Aoki T, Nanba M, Murata H, Yuasa M, Maruyama I, Maekawa T.
    • Journal Title

      Brain Res. 1292

      Pages: 180-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] The effect of chemical and/or mechanical conditioning on the Er : YAG laser treated root cementum : analysis of surface morphology and periodontal ligament fibroblast attachment2008

    • Author(s)
      Maruyama H, Aoki A, Sasaki KM, Takasaki AA, Iwasaki K, Ichinose S, Oda S, Ishikawa I, Izumi Y.
    • Journal Title

      Lasers Surg Med 40(3)

      Pages: 211-222

    • Data Source
      KAKENHI-PROJECT-18390561
  • [Journal Article] High mobility group box chromosomal protein 1 in patients with renal diseases.2008

    • Author(s)
      Sato F, Maruyama S, Hayashi H, Uchimura T, et. al.
    • Journal Title

      Nephron Clin Pract 108

      Pages: 194-201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590564
  • [Journal Article] Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes.2008

    • Author(s)
      Ito T, Kawahara K, Maruyama I, and, et al.
    • Journal Title

      Arterioscler Thromb Vase Biol. 28(10)

      Pages: 1825-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells.2008

    • Author(s)
      Kawahara K, Hashiguchi T, Maruyama I, and, et al.
    • Journal Title

      Int J Mol Med. 22(5)

      Pages: 639-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes.2008

    • Author(s)
      Ito T, Kawahara K, Maruyama I, et al.
    • Journal Title

      Biochem Biophys Res Commun. 377(2)

      Pages: 642-647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Proteolytic cleavage of high mobility group box 1 protein by thrombin-thrombomodulin complexes.2008

    • Author(s)
      Ito T, Kawahara K, Maruyama I, et al.
    • Journal Title

      Arterioscler Thromb Vasc Biol. 28(10)

      Pages: 1825-1830

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] Extracellular high mobility group box chromosomal protein 1 is a coupling factor for hypoxia and inflammation in arthritis2008

    • Author(s)
      Hamada T, Torikai M, Kuwazuru A, Tanaka M, Horai N, Fukuda T, Yamada S, Nagayama S, Hashiguchi K, Sunahara N, Fukuzaki K, Nagata R, Komiya S, Maruyama I, Fukuda T, Abeyama K
    • Journal Title

      Arthritis Rheum(IF : 7.677) 58(9)

      Pages: 2675-2685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] The role of water channel aquaporin 3 in the mechanism of TNF alpha-mediated proinflammatory events2008

    • Author(s)
      Tancharoen S, Matsuyama T, Abeyama K, Matsushita K. Kawahara K , Sangalungkarm V, Tokuda M, Hashiguchi T, Maruyama I, Izumi Y
    • Journal Title

      Implication in periodontal inflammation(IF : 3.643) 217(2)

      Pages: 338-349

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008

    • Author(s)
      中島利博、八木下尚子、山野嘉久、丸山征郎他19名
    • Journal Title

      A&R 60

      Pages: 63-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20013045
  • [Journal Article] High-mobility group box 1 protein in endophthalmitis.2008

    • Author(s)
      Arimura N, Ki-I Y, Hashiguchi T, Sakamoto T, Maruyama I
    • Journal Title

      Graefes Arch Clin Exp Ophthalmol 24

      Pages: 1053-1058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Increased prevalence of group Aβ-hemolytic streptococcus among an ethnic population in Kyrgyzstan detected by the rapid antigen detection test2008

    • Author(s)
      Omurzakova OA, Yamano Y, Sato T, Izumi T, Azakami K, Hasegawa D, Fujii R, Yagishita N, Aratani S, Kabaeva ZS, Mirrakhimov MM, Kami M, Maruyama I, Osame M, Yokota S, Nishioka K, Nakajima T
    • Journal Title

      Molecular Medicine Reports

      Volume: 1 Pages: 869-874

    • DOI

      10.3892/mmr_00000043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] Tumor necrosisi factor-alpha stimulates gingival epithelial cells to release high mobility-group box 12008

    • Author(s)
      Morimoto, Y., Kawahara, K-I., Tancharoen, S., Kikuchi, K., Matsuyama, T., Hashiguchi, T., Izumi, Y., Maruyama, I.
    • Journal Title

      J Periodontal Res. 43

      Pages: 76-83

    • Data Source
      KAKENHI-PROJECT-18390561
  • [Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008

    • Author(s)
      中島利博、八木下尚子、山野嘉久、丸山征郎, 他19名
    • Journal Title

      A&R 60

      Pages: 63-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] A novel function of the receptor for advanced glycation end products (RAGE) in association with tumorigenesis and tumor differentiation of HCC2008

    • Author(s)
      Hiwatashi K, Ueno S, Abeyama K, Kubo F, Sakoda M, Maruyama I, Hamanoue M, Natsugoe S, Aikou T
    • Journal Title

      Ann Surg Oncol(IF : 3.917) 15(3)

      Pages: 923-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] The role of water channel aquaporin 3 in the mechanism of TNF-alpha-mediated proinflammatory events : Implication in periodontal inflammation2008

    • Author(s)
      S. Tancharoen, T. Matsuyama, K. Abeyama, K. Matsushita, K. Kawahara, V. Sangalungkarn, M. Tokuda, T. Hashiguchi, I. Maruyama, Y. Izumi
    • Journal Title

      J Cell Physiol 217

      Pages: 338-349

    • Data Source
      KAKENHI-PROJECT-18390561
  • [Journal Article] Novel transcriptional complex of ILF3-GABP α activates synoviolin promoter in rheumatoid synovial cells2008

    • Author(s)
      中島利博、八木下尚子、山野嘉久、丸山征郎他19名
    • Journal Title

      A&R 60

      Pages: 63-72

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20059033
  • [Journal Article] Induction of high mobility group box 1 release from serotonin-stimulated human umbilical vein endothelial cells.2008

    • Author(s)
      Kawahara K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Int J Mol Med. 22(5)

      Pages: 639-644

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Journal Article] High mobility group box chromosomal protein 1 in patients with renal diseases2008

    • Author(s)
      Sato F, Maruyama S, Hayashi H, Uchimura T et.al.
    • Journal Title

      Nephron Clin Pract 108

      Pages: 194-201

    • Data Source
      KAKENHI-PROJECT-19590564
  • [Journal Article] C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells.2007

    • Author(s)
      Kawahara K, Biswas KK, Maruyama I, et. al.
    • Journal Title

      Cardiovasc Pathol. 17(3)

      Pages: 129-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Serum VEGF-as a prognostic factor of atherosclerosis.2007

    • Author(s)
      Kimura K, Hashiguchi T, Deguchi T, Horinouchi S, Uto T, Oku H, Setoyama S, Maruyama I, Osame M, Arimura K
    • Journal Title

      Atherosclerosis 194

      Pages: 182-188

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] HMGB1 release in co-cultures of porcine endothelial and human T cells2007

    • Author(s)
      Kawahara K, Setoyama K, Maruyama I and, et. al.
    • Journal Title

      Xenotransplantation. 14(6)

      Pages: 636-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659470
  • [Journal Article] Physical Adsorption of Human Thrombomodulin (ART -123) onto Polymeric Biomaterials for Developing an Antithrombogenic Blood-Contacting Material2007

    • Author(s)
      M.Matsusaki, M.Omichi, I.Maruyama, M.Akashi
    • Journal Title

      J. Biomed. Mater. Res. (in press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Journal Article] HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques.2007

    • Author(s)
      Inoue K, Kawahara K, Maruyama I and, et. al.
    • Journal Title

      Cardiovasc Pathol. 16(3)

      Pages: 136-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] HMGB1 release in co-cultures of porcine endothelial and human T cells.2007

    • Author(s)
      Kawahara K, Takao S, Maruyama I.
    • Journal Title

      Xenotransplantation 14

      Pages: 636-641

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17100007
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats2007

    • Author(s)
      Ito T, Kawahara K, Nakamura T, Yamada S, Nakamura T, Abeyama K, Hashiguchi T, Maruyama I
    • Journal Title

      J Thromb Haemost(IF : 5.947) 5(1)

      Pages: 109-1116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase 'Synoviolin'.2007

    • Author(s)
      Yamasaki S, Yagishita N, Sasaki T, Nakazawa M, Kato Y, Yamadera T, Bae E, Toriyama S, Ikeda R, Zhang L, Fujitani K, Yoo E, Tsuchimochi K, Ohta T, Araya N, Fujita H, Aratani S, Eguchi K, Komiya S, Maruyama I, Higashi N, Sato M, Senoo H, Ochi T, Yokoyama S, Amano T, Kim J, Gay S, Fukamizu A, Nishioka K, Tanaka K, Nakajima T
    • Journal Title

      EMBO J 26(1)

      Pages: 113-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249052
  • [Journal Article] HMGB1 release in co-cultures of porcine endothelial and human T cells2007

    • Author(s)
      Kawahara K, Setoyama K, Maruyama I and, et. al.
    • Journal Title

      Xenotransplantation. 14(6)

      Pages: 636-41

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] C-reactive protein induces high-mobility group box-1 protein release through activation of p38MAPK in macrophage RAW264.7 cells.2007

    • Author(s)
      Kawahara K, Biswas KK, Maruyama I, et. al.
    • Journal Title

      Cardiovasc Pathol. 17(3)

      Pages: 129-38

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659470
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats.2007

    • Author(s)
      Ito T, Maruyama I, et al.
    • Journal Title

      J Thromb Haemost. 5(1)

      Pages: 109-116

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] HMGB1 expression by activated vascular smooth muscle cells in advanced human atherosclerosis plaques.2007

    • Author(s)
      Inoue K, Kawahara K, Maruyama I and, et. al.
    • Journal Title

      Cardiovasc Pathol. 16(3)

      Pages: 136-43

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659470
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats2007

    • Author(s)
      Ito T, Maruyama I, et. al.
    • Journal Title

      J Thromb Haemost 5(1)

      Pages: 109-16

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] High-mobility group box 1 protein promotes development of microvascular thrombosis in rats.2007

    • Author(s)
      Ito T, Maruyama I, et al.
    • Journal Title

      J Thromb Haemost. 5(1)

      Pages: 109-16

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Stromal-derived factor-1 and inflammatory cytokines in retinal vein occlusion.2007

    • Author(s)
      Ki-I Y, Arimura N, Noda Y, Yamakiri K, Doi N, Hashiguchi T, Maruyama I, Shimura M, Sakamoto T
    • Journal Title

      Curr Eye Res 32

      Pages: 1065-1072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification2007

    • Author(s)
      Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H
    • Journal Title

      Mol Cell Biol(IF : 6.42) 27(16)

      Pages: 5650-5663

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] High-mobility group box ; protein promotes development of microvascula thrombosis in rats2007

    • Author(s)
      Ito, T., Maruyama, I., et. al.
    • Journal Title

      J Thromb Haemost(peer reviewed) 5(1)

      Pages: 109-16

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition.2006

    • Author(s)
      Nakajima Y, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition2006

    • Author(s)
      Nakajima Y, Furuichi Y, Biswas KK, Hashiguchi T, Kawahara K, Yamaji K, .Uchimura T, Izumi Y, Maruyama I.
    • Journal Title

      FEBS Letter. 580(2)

      Pages: 613-9

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kB pathway inhibition2006

    • Author(s)
      Yumiko Nakajima, Yasushi Furuichi, Kamal Krishna Biswas, Teruto Hashiguchi, Ko-ichi Kawahara, Kazuyo Yamaji, Tomonori Uchimura, Yuichi Izumi, Ikuro Maruyama
    • Journal Title

      FEBS Letters 580

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-18390561
  • [Journal Article] Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.2006

    • Author(s)
      Biswas KK, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580・2

      Pages: 703-710

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition2006

    • Author(s)
      Nakajima, Y., Furuichi, Y., Biswas, KK., Hashiguchi, T., Kawahara, K., Yamaji, K., Uchimura, T., Izumi, Y., Maruyama, I
    • Journal Title

      FEBS Lett 23, 580(2)

      Pages: 613-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] 炎症隔離分子としてのトロンボモジュリン2006

    • Author(s)
      阿辺山和浩、吉元 寧、丸山征郎
    • Journal Title

      血管医学((特集 : 血管炎のオムニバス)) vol. 7.No.3

      Pages: 19-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] 炎症隔離分子としてのトロンボモジュリン2006

    • Author(s)
      阿辺山 和浩、丸山 征郎
    • Journal Title

      血管医学(メディカルレビュー社) 7(3)

      Pages: 19-25

    • Data Source
      KAKENHI-PROJECT-18390481
  • [Journal Article] Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line(HuH-7)through the activation of JNK1/2 and the downxegulation of Akt2006

    • Author(s)
      BisNas KK, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 703-10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line(HuH-7)through the activation of JNK1/2 and the downregulation of Akt2006

    • Author(s)
      Biswas KK, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 703-10

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.2006

    • Author(s)
      Biswas KK, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 703-710

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition.2006

    • Author(s)
      Nakajima Y, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition2006

    • Author(s)
      Nakajima, Y., Hashiguchi, T., Maruyama, I., et. al.
    • Journal Title

      FEBS Letters(peer reviewed) 580(2)

      Pages: 613-9

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Endocannabinoid,anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition2006

    • Author(s)
      Nakajima Y, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 613-9

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB inhibition.2006

    • Author(s)
      Nakajima Y, Furuichi Y, Biswas KK, Hashiguchi T, Kawahara K, Yamaji K, Uchimura T, Izumi Y, Maruyama I
    • Journal Title

      FEBS Letter. 580(2)

      Pages: 613-9

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Endocannabinoid, anandamide in gingival tissue regulates the periodontal inflammation through NF-kappaB pathway inhibition.2006

    • Author(s)
      Nakajima Y, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580・2

      Pages: 613-619

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.2006

    • Author(s)
      Biswas KK, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      FEBS Letters 580(2)

      Pages: 703-710

    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] 腎疾患患者におけるHMGB1の意義に関する検討2005

    • Author(s)
      佐藤文彦, 丸山彰一, 三木祐介, 倉田圭, 森田良樹, 湯澤由紀夫, 内村友則, 丸山征朗, 松尾清一
    • Journal Title

      日本腎臓学会誌 47巻3号

      Pages: 287-287

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Thrombosis Research 115・4

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] HMGB1 contributes to the development of acute lung injury after hemorrhage.2005

    • Author(s)
      Kim JY, Maruyama I, Ishizaka A, Abraham E.et al.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol. 288・(5)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K, Stern DM, Ito Y, Kawahara KI, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I.
    • Journal Title

      J Clin Invest. 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatroban.2005

    • Author(s)
      Sarker KP, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Pathophysiology of Haemostasis and Thrombosis 34(1)

      Pages: 41-47

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Roxithromycin inhibits constitutive activation of nuclear factor {kappa}B by diminishing oxidative stress in a rat model of hepatocellular carcinoma2005

    • Author(s)
      Ueno S, Aoki D, Kubo F, Hiwatashi K, Matsushita K, Oyama T, Maruyama I, Aikou T.
    • Journal Title

      Clin Cancer Res. 11(15)

      Pages: 5645-5650

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370359
  • [Journal Article] HMGB1 contributes to the development of acute lung injury after hemorrhage.2005

    • Author(s)
      Kim JY, Park JS, Strassheim D, Douglas I, Diaz del Valle F, Asehnoune K, Mitra S, Kwak SH, Yamada S, Maruyama I, Ishizaka A, Abraham E.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol. 288(5)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] 維持透析者における偽陽性P-ANCAの対応抗原としてのHMGB12005

    • Author(s)
      内村友則, 丸山征郎 ほか
    • Journal Title

      日本透析医学会雑誌 38・1

      Pages: 681-681

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Abeyama K, Hashiguchi T, Uchimura T, Maruyama I. et al.
    • Journal Title

      Thrombosis Research. 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest (In press)

    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein a novel anti-inflammatory mechanism2005

    • Author(s)
      Abeyama, K., Maruyama, I., et. al.
    • Journal Title

      J Clin Invest(peer reviewed) 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・5

      Pages: 1267-1274

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production2005

    • Author(s)
      Aoki D, Ueno S, Kubo F, Oyama T, Sakuta T, Matsushita K, Maruyama I, Aikou T.
    • Journal Title

      Anticancer Res. 25(1A)

      Pages: 133-138

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14370359
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Wang Y, Liu Y, Abeyama K, Hashiguchi T, Uchimura T, Krishna Biswas K, Iwamoto H, Maruyama I.
    • Journal Title

      Thromb Res. 115(4)

      Pages: 319-325

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Roxithromycin inhibits angiogenesis of human hepatoma cells in vivo by suppressing VEGF production.2005

    • Author(s)
      Aoki D, Ueno S, Kubo F, Oyama T, Sakura T, Matsushita K, Maruyama I, Aikou T.
    • Journal Title

      Anticancer Res 25(1A)

      Pages: 133-138

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370359
  • [Journal Article] Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma(NB-1) cells by argatroban.2005

    • Author(s)
      Sarker KP, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Pathophysiology of Haemostasis and Thrombosis 34(1)

      Pages: 41-47

    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatroban.2005

    • Author(s)
      Sarker KP, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Pathophysiology of Haemostasis and Thrombosis 34・1

      Pages: 41-47

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] 腎結石形成モデルにおける腎不全発症機構についての研究2005

    • Author(s)
      大山陽子, 内村友則, 丸山征郎 ほか
    • Journal Title

      臨床化学 34・1

      Pages: 270-270

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Studies on unfolded beta-microglobulin at C-terminal in dialysis-related amyloidosis.2005

    • Author(s)
      Motomiya Y, Ando Y, Amano I, Uchimura T, Maruyama I. et al.
    • Journal Title

      Kidney International 67(1)

      Pages: 314-320

    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji, K., Abeyama, K., Hashiguchi, T.,Uchimura, T., Maruyama, I., et. al.
    • Journal Title

      Thromb Res 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein,a novel anti-inflammatory mechanism2005

    • Author(s)
      Abeyama, K., Maruyama, I., et. al.
    • Journal Title

      J CIin Invest 115・5

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Studies on unfolded beta-microglobulin at C-terminal in dialysis-related amyloidosis2005

    • Author(s)
      Motomiya Y, Ando Y, Amano I, Uchimura T, Maruyama I, et. al.
    • Journal Title

      Kidney International 67(1)

      Pages: 314-20

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma(NB-1) cells by argatroban2005

    • Author(s)
      Sarker, KP., Hashiguchi, T., Maruyama, I., et. al.
    • Journal Title

      Pathophysiology of Haemostasis and Thrombosis(peer reviewed) 34(1)

      Pages: 41-7

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidani properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji, K., Hashiguchi, T., Maruyama, I., et. al.
    • Journal Title

      Thrombosis Research(peer reviewed) 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Studies on unfolded beta-microglobulin at C-terminal in dialysis-related amyloidosis2005

    • Author(s)
      Motomaiya, Y, Amano, I, Uchimura, T., Maruyama, I, et. al.
    • Journal Title

      Kidney International 67(1)

      Pages: 314-20

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1)cells by argatroban2005

    • Author(s)
      Sarker KP, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      Pathophysiology of Haemostasis and Thrombosis 34(1)

      Pages: 41-7

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji K, Abeyama K, Hashiguchi T, Uchimura T, Maruyama I., et. al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590496
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Roxithromycin inhibits constitutive activation of nuclear factor {kappa}B by deminishing oxidative stress in a rat model of hepatocellular carcinoma2005

    • Author(s)
      Ueno S, Aoki D, Kudo F, Hiwatashi K, Matsushita K, Oyama T, Maruyama I, Aikou T.
    • Journal Title

      Clin Cancer Res 11(15):

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14370359
  • [Journal Article] Activated protein C,a natural anticoagulant protein,has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji K, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation2005

    • Author(s)
      Yamaji K, Hashiguchi T, Maruyama I, et. al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-25

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590888
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high mobility group-B1 protein, a novel anti-inflammatory mechanism.2005

    • Author(s)
      Abeyama, K., Maruyama, I., et al.
    • Journal Title

      J Clin Invest 115・5

      Pages: 1267-1274

    • Data Source
      KAKENHI-PROJECT-17659294
  • [Journal Article] Activated protein C, a natural anticoagulant protein, has antioxidant properties and inhibits lipid peroxidation and advanced glycation end products formation.2005

    • Author(s)
      Yamaji K, Hashiguchi T, Maruyama I, et al.
    • Journal Title

      Thrombosis Research 115(4)

      Pages: 319-325

    • Data Source
      KAKENHI-PROJECT-17390282
  • [Journal Article] The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism.2005

    • Author(s)
      Abeyama K, Stern DM, Ito Y, Kawahara K, Yoshimoto Y, Tanaka M, Uchimura T, Ida N, Yamazaki Y, Yamada S, Yamamoto Y, Yamamoto H, Iino S, Taniguchi N, Maruyama I.
    • Journal Title

      J Clin Invest. 115(5)

      Pages: 1267-1274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] The antimetastatic role of thrombomodulin expression in islet cell-derived tumors and its diagnostic value.2004

    • Author(s)
      Iino S, Abeyama K, Kawahara K, Yamakuchi M, Hashiguchi T, Matsukita S, Yonezawa S, Taniguchi S, Nakata M, Takao S, Aikou T, Maruyama I.
    • Journal Title

      Clin Cancer Res. 10(18 pt.1)

      Pages: 6179-6188

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] 3章 血管内皮細胞による炎症・凝固系制御、-炎症反応系と血液凝固系のクロストーク-2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      血管内皮細胞研究フロンティア

      Pages: 21-23

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] 病態生理 : 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Contributions of high mobility group box in experimental and clinical acute lung injury.2004

    • Author(s)
      Ueno H, Matusda T, Tanaka, Maruyama I, Ishizaka A. et al.
    • Journal Title

      Am J Respir Crit Care Med. 170・(12)

      Pages: 1310-1316

    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Regulatory cross-talk between inflammation and blood coagulation. (in Japanese)2004

    • Author(s)
      Abeyama K, Maruyama I.
    • Journal Title

      Kekkan-Naihisaibou kenkyuu Frontier

      Pages: 21-23

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Thrombomodulin expression on Langerhans' islet : can endogenous 'anticoagulant on demand' overcome detrimental thrombotic complications in clinical islet transplantation?2004

    • Author(s)
      Iino S, Abeyama K, Kawahara KI, Aikou T, Maruyama I.
    • Journal Title

      J Thromb Haemost. 2(5)

      Pages: 833-834

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] (総説)病態生理 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Data Source
      KAKENHI-PROJECT-16659493
  • [Journal Article] Contributions of high mobility group box protein in experimental and clinical acute lung injury.2004

    • Author(s)
      Ueno H, Matsuda T, Hashimoto S, Amaya F, Kitamura Y, Tanaka M, Kobayashi A, Maruyama I, Yamada S, Hasegawa N, Soejima J, Koh H, Ishizaka A.
    • Journal Title

      Am J Respir Crit Care Med. 170(12)

      Pages: 1310-1316

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome.2004

    • Author(s)
      Motobe T, Komiya S, Maruyama I., et al.
    • Journal Title

      Shock 21・(1)

      Pages: 8-12

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Inflammation and its regulatory system. (in Japanese)2004

    • Author(s)
      Abeyama K, Maruyama I.
    • Journal Title

      Nippon Rinsho 62(12)

      Pages: 2229-2235

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] (総説)病態生理 炎症とその制御システム2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      日本臨床 62(12)

      Pages: 2229-2235

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Endogenous cannabinoids are candidates for lipid mediators of bone cement implantation syndrome.2004

    • Author(s)
      Motobe T, Hashiguchi T, Uchimura T, Yamakuchi M, Taniguchi N, Komiya S, Maruyama I.
    • Journal Title

      Shock. 21(1)

      Pages: 8-12

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] 3章 血管内皮細胞による炎症・凝固系制御、-炎症反応系と血液凝固系のクロストーク-2004

    • Author(s)
      阿辺山和浩, 丸山征郎
    • Journal Title

      血管内皮細胞研究フロンティア

      Pages: 21-23

    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Contributions of high mobility group box protein in experimental and clinical acute lung injury.2004

    • Author(s)
      Ueno H, Matsuda T, Tanaka, Maruyama I, Ishizaka A.et al.
    • Journal Title

      Am J Respir Crit Care Med. 170・(12)

      Pages: 1310-1316

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Decreased total nitric oxide production in patients with duchenne muscular dystrophy.2004

    • Author(s)
      Kasai T, Abeyama K, Hashiguchi T, Fukunaga H, Osame M, Maruyama I.
    • Journal Title

      J Biomed Sci. 11(4)

      Pages: 534-537

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390516
  • [Journal Article] Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis.2003

    • Author(s)
      Biswas KK, Hashiguchi T, Maruyama I.
    • Journal Title

      Hepatology 38・(5)

      Pages: 1167-1177

    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2.2003

    • Author(s)
      Yamada S, Inoue K, Yakabe K, Imaizumi H, Maruyama I.
    • Journal Title

      Clin Chem. 49(9)

      Pages: 1535-1537

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] High mobility group protein 1 (HMGB1) quantified by ELISA with a monoclonal antibody that does not cross-react with HMGB2.2003

    • Author(s)
      Yamada, S., Inoue, K., Yakabe, K., Imaizumi, H., Maruyama, I.
    • Journal Title

      Clin Chem 49・(9)

      Pages: 1535-1537

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Membrane cholesterol but not putative receptors mediates anandamide-induced hepatocyte apoptosis.2003

    • Author(s)
      Biswas KK, Sarker KP, Abeyama K, Kawahara K, Iino S, Otsubo Y, Saigo K, Izumi H, Hashiguchi T, Yamakuchi M, Yamaji K, Endo R, Suzuki K, Imaizumi H, Maruyama I.
    • Journal Title

      Hepatology. 38(5)

      Pages: 1167-1177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390546
  • [Journal Article] Predictive value of serial platelet count and VEGF determination for the management of DIC in the Crow-Fukase (POEMS) syndrome.2003

    • Author(s)
      Tokashiki T, Hashiguchi T, Arimura K, Eiraku N, Maruyama I, Osame M.
    • Journal Title

      Intern Med. 42(12)

      Pages: 1240-1243

    • NAID

      130000767039

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590901
  • [Journal Article] Highly accumulated platelet vascular endothelial growth factor in coagulant thrombotic region.2003

    • Author(s)
      Arisato T, Hashiguchi T, Sarker KP, Arimura K, Asano M, Matsuo K, Osame M, Maruyama I.
    • Journal Title

      J Thromb Haemost. (12)

      Pages: 2589-2593

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590901
  • [Journal Article] The agonist of the protease-activated receptor-1(PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells.2003

    • Author(s)
      Arisato T, Sarker KP, Kawahara K, Nakata M, Hashiguchi T, Osame M, Kitajima I, Maruyama I.
    • Journal Title

      Cell Mol Life Sci. 60(8)

      Pages: 1716-1724

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590901
  • [Journal Article] Association between reduced ADAMTS13 and diabetic nephropathy

    • Author(s)
      Taniguchi S, Hashiguchi T, Ono T, Takenouchi K, Nakayama K, Kawano T, Kato K, Matsushita R, Nagatomo M, Nakamura S, Nakashima T, Maruyama I
    • Journal Title

      Thromb Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Journal Article] Physical Adsorption of Human Thrombomodulin (ART-123) onto Polymeric Biomaterials for Developing an Antithrombogenic Blood-Contacting Material

    • Author(s)
      M.Matsusaki, M.Omichi, I.Maruyama, M.Akashi
    • Journal Title

      J.Biomed.Mater.Res. (in press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Journal Article] Vitreous Mediators after Intravitreal Bevacizumab or Triamcinolone Acetonide in Eyes with Proliferative Diabetic Retinopathy・

    • Author(s)
      Arimura N, Otsuka H, Yamakiri K, Sonoda Y, Nakao S, Noda Y, Hashiguchi T, Maruyama I, Sakamoto T.
    • Journal Title

      Ophthalmology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Journal Article] High-mobility group box-1 protein promotes granulomatous nephritis in adenine-induced nephropathy.

    • Author(s)
      Oyama Y, Hashiguchi T, Taniguchi N, Tancharoen S, Uchimura T, Biswas KK, Kawahara K, Nitanda T, Umekita Y, Lotz M, Maruyama I
    • Journal Title

      Lab Invest (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 癌の診断デバイス2018

    • Inventor(s)
      堀貫治、平山真、丸山征郎、田口好弘、黒川洋、水口博義、小林謙也
    • Industrial Property Rights Holder
      広島大学、鹿児島大学、アルプスアルパイン、京都モノテック
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-092557
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-18K19587
  • [Patent] タンパク質分離デバイス、タンパク質を分離する方法、および、高マンノース型糖鎖の構造を決定する方法2015

    • Inventor(s)
      丸山征郎、堀貫治、坂口剛正、平山真、黒川洋
    • Industrial Property Rights Holder
      鹿児島大学、広島大学、旭化成メディカル㈱
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-026996
    • Filing Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-26293385
  • [Patent] タンパク質分離デバイス、タンパク質を分離する方法、および、高マンノース型糖鎖の構造を決定する方法2015

    • Inventor(s)
      丸山征郎、堀貫治、坂口剛正、平山真、黒川洋
    • Industrial Property Rights Holder
      鹿児島大学、広島大学、旭化成メディカル㈱
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-026996
    • Filing Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-26670790
  • [Patent] 糖尿病性腎症患者の病態把握方法2011

    • Inventor(s)
      橋口照人 谷口尚太郎 丸山征郎 小野智子 古崎文雄
    • Industrial Property Rights Holder
      鹿児島大学 他
    • Acquisition Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Patent] 歯周病特異的ペプチド、並びにそれを用いた歯周病の治療および診断2010

    • Inventor(s)
      丸山征郎, 橋口照人, タンジャルーンサランヤー, 川原幸一, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Industrial Property Number
      2010-061673
    • Filing Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 歯周病特異的ペプチド、並びにそれを用いた歯周病の治療および診断2010

    • Inventor(s)
      丸山征郎、橋口照人, タンジャルーン サランヤー, 川原幸一, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Industrial Property Number
      2010-061673
    • Filing Date
      2010-03-17
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 新規癌マーカーおよびそれを用いた診断2009

    • Inventor(s)
      橋口照人, 夏越祥次, 丸山征郎, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Filing Date
      2009-01-07
    • Acquisition Date
      2009-07-16
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 新規癌マーカーおよびそれを用いた診断2008

    • Inventor(s)
      丸山征郎、橋口照人、夏越祥次、田中憲次、李 良子
    • Industrial Property Rights Holder
      鹿児島大学(株)プロトセラ
    • Industrial Property Number
      2008-000776
    • Filing Date
      2008-01-07
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 新規癌マーカーおよびそれを用いた診断2008

    • Inventor(s)
      橋口照人, 夏越祥次, 丸山征郎, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Industrial Property Number
      2008-000776
    • Filing Date
      2008-01-07
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 新規疾患マーカーおよびそれを用いた診断2007

    • Inventor(s)
      橋口照人, 夏越祥次, 丸山征郎, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Filing Date
      2007-12-12
    • Acquisition Date
      2008-06-19
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 新規癌マーカーおよびそれを用いた診断2007

    • Inventor(s)
      橋口照人, 夏越祥次, 丸山征郎, 田中憲次, 李良子
    • Industrial Property Rights Holder
      鹿児島大学
    • Industrial Property Number
      2008-549347
    • Filing Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Patent] 多孔質基材2006

    • Inventor(s)
      上野良之, 菅谷博之, 舩木隆文, 加藤真哉, 明石満, 丸山征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムテイーハイブリッド, 明石満, 丸山征郎
    • Patent Publication Number
      2007-029716
    • Filing Date
      2006-06-20
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Patent] 放射線照射された改質基材2005

    • Inventor(s)
      上野良之, 菅谷博之, 舩木隆文, 加藤真哉, 明石満, 丸山征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムテイーハイブリッド, 明石満, 丸山征郎
    • Patent Publication Number
      2006-271809
    • Filing Date
      2005-03-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Patent] 体外循環医療カラム用補助用具2005

    • Inventor(s)
      上野 良之, 菅谷 博之, 舩木 隆文, 加藤 真哉, 明石 満, 丸山 征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムティーハイブリッド, 明石 満, 丸山 征郎
    • Filing Date
      2005
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Patent] 放射線照射された改質基材2005

    • Inventor(s)
      上野 良之, 菅谷 博之, 舩木 隆文, 加藤 真哉, 明石 満, 丸山 征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムティーハイブリッド, 明石 満, 丸山 征郎
    • Filing Date
      2005
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Patent] 多孔質基材2005

    • Inventor(s)
      上野 良之, 菅谷 博之, 舩木 隆文, 加藤 真哉, 明石 満, 丸山 征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムティーハイブリッド, 明石 満, 丸山 征郎
    • Filing Date
      2005
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Patent] 体外循環医療カラム用補助用具2005

    • Inventor(s)
      上野良之, 菅谷博之, 舩木隆文, 加藤真哉, 明石満, 丸山征郎
    • Industrial Property Rights Holder
      東レ株式会社, 株式会社ビーエムテイーハイブリッド, 明石満, 丸山征郎
    • Patent Publication Number
      2006-271839
    • Filing Date
      2005-03-30
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16300156
  • [Presentation] Preconditioning exercise in rats attenuates early brain injury resulting from subarachnoid hemorrhage by reducing oxidative stress, inflammation, and neuronal apoptosis.2022

    • Author(s)
      大塚 章太郎, 松岡輝樹, 松崎凌真, 中小川智美, 谷明, 則松貢輔, 高田聖也, 中西和毅, 丸山征郎, 榊間春利 , 菊池清志
    • Organizer
      第45回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-20H04039
  • [Presentation] 抗酸化力を高める意義| 術後癒着に備える2021

    • Author(s)
      菊池 清志, 瀬戸山 健太郎, 大塚 章太郎, 高田 聖也, 中西 和毅, 則松 貢輔, 谷 明, 榊間 春利, 川原 幸一, 丸山 征郎, 田中 永一郎, 内門 久明
    • Organizer
      第18回 予防医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K11640
  • [Presentation] 抗酸化力を高める意義| 脳梗塞の発症・加療に備える2021

    • Author(s)
      菊池 清志, 瀬戸山 健太郎, 大塚 章太郎, 高田 聖也, 中西 和毅, 則松 貢輔, 谷 明, 榊間 春利, 川原 幸一, 丸山 征郎, 田中 永一郎
    • Organizer
      第18回 予防医学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K11640
  • [Presentation] 細胞外Nucleophosminの受容体は TLR-4である2020

    • Author(s)
      中富康太, 董建暉, 金本一誠, Ronny Christiadi Salim, 上野光理, Salunya Tancharoen, 菊池清志 伊藤隆史, 丸山征郎, 川原幸一
    • Organizer
      日本薬学会
    • Data Source
      KAKENHI-PROJECT-18H02906
  • [Presentation] ヒストンH2AとH2BはMD2/ERK1/2を介してTNF-αを誘導する2020

    • Author(s)
      上野 光理, Ronny Christiadi Salim, 石濱 一貴, 朝田 成重, 山下 侑子, Tancharoen Salunya, 菊池 清志, 伊藤 隆史, 丸山 征郎, 川原 幸一
    • Organizer
      第42回日本血栓止血学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02906
  • [Presentation] Effects of detraining on neuroprotective effects due to preconditioning exercise-induced brain tolerance after ischemic stroke of rat.2020

    • Author(s)
      Shotaro Otsuka, Akira Tani, Yuki Itashiki, Kosuke Norimatu, Seiya Takada, Kazuki Nakanishi, Maruyama Ikuro, Harutoshi Sakakima.
    • Organizer
      第43回日本神経科学学会
    • Data Source
      KAKENHI-PROJECT-20H04039
  • [Presentation] recombinant TM の開発ーDICトリガー因子:トロンビンのベクトル変換によるDIC治療ストラテジー2019

    • Author(s)
      丸山 征郎
    • Organizer
      第41回日本血栓止血学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] TNF-a induction by Histone H2A and H2B is mediated via ERK1/2 in RAW264.7 cells.2019

    • Author(s)
      Hikari Ueno, Kota Nakatomi, Shuto Anan, Salunya Tancharoen, Kiyoshi Kikuchi, Takashi Ito, Ikuro Maruyama, Ko-ichi Kawahara
    • Organizer
      International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02906
  • [Presentation] TNF-a induction by Histone H2A and H2B is mediated via ERK1/2 in RAW264.7 cells.2019

    • Author(s)
      Ueno H, Nakatomi K, Anan S, Tancharoen S, Kikuchi K, Ito T, Maruyama I, Kawahara KI
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03926
  • [Presentation] The extracellular Nucleophosmin Receptor is TLR-42019

    • Author(s)
      Kota Nakatomi, Ronny Christiadi Salim, Issey Kanemoto, Hikari Ueno, Dong Jianhui, Salunya Tancharoen, Kiyoshi Kikuchi, Takashi Ito, Ikuro Maruyama, Ko-ichi Kawahara.
    • Organizer
      International DAMPs and Alarmins Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02906
  • [Presentation] Chinese herbal medicine "Wu Ling San" had a renal protecting function in crystal induced granulomatous nephritis in rats.2019

    • Author(s)
      Oyama Y, Tancharoen S, Ito T, Yamakuchi M, Higashi S, Hashiguchi T, Maruyama I.
    • Organizer
      9th International Symposium DAMPS and HMGB1, Okayama, Japan 2019.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09310
  • [Presentation] Endothelial anticoagulant thrombomodulin binds and neutralizes HMGB1, histones and LPS, and induces resolution of damage through protein C activation2019

    • Author(s)
      Ikuro Maruyama
    • Organizer
      9th International DAMPs and Alarmins Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] 尿酸は rtPA線溶効果を増強するか?― 脳梗塞急性期治療における閉塞血管の再開通率向上を目指して―2019

    • Author(s)
      菊池清志, 伊藤隆史, 瀬戸山健太郎, 細川和也, 丸山征郎
    • Organizer
      第19回 TTMフォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K10746
  • [Presentation] 急性血液浄化の新視点:exosomeとRAMPs2018

    • Author(s)
      丸山 征郎
    • Organizer
      第29回日本急性血液浄化学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] 急性血液浄化の新視点:exosomeとRAMPMs2018

    • Author(s)
      丸山 征郎
    • Organizer
      第29回日本急性血液浄化学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19587
  • [Presentation] The impact of endothelial marker on catheter ablation in patients with atrial fibrillation2018

    • Author(s)
      Namino F, Yamakuchi M, Iriki Y, Okui H, Ichiki H, Maenosono R, Masamoto I, Hashiguchi T, Ohishi M, Maruyama I
    • Organizer
      The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05229
  • [Presentation] 病態拡大の新しい使者:exosomeが参画した新しいショック病2018

    • Author(s)
      丸山 征郎
    • Organizer
      第33回日本Shock学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] 血管作動因子としてのPAMPs/DAMPsとその作用2018

    • Author(s)
      丸山征郎
    • Organizer
      第47回日本心脈管作動物質学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] 病態拡大の新しい使者:exosomeが参画した新しいショック病像2018

    • Author(s)
      丸山 征郎
    • Organizer
      第33回日本Shock学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19587
  • [Presentation] エクソソームとshock、炎症との関わり2017

    • Author(s)
      丸山征郎
    • Organizer
      日本集中治療医学会 第1回東海北陸支部学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] 血管内皮細胞と動脈硬化2017

    • Author(s)
      丸山征郎
    • Organizer
      第49回日本動脈硬化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H04363
  • [Presentation] CalDAG-GEFI分子異常による血小板機能異常症2017

    • Author(s)
      古城 剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、波野史典、Sushil Panta 、松下昌風、丸山征郎、髙嶋 博、橋口照人
    • Organizer
      第62回日本臨床検査医学会 九州地方会 第28回日本臨床化学会 九州支部総会
    • Place of Presentation
      久留米大学病院 筑水会館(福岡県久留米市)
    • Data Source
      KAKENHI-PROJECT-16H05229
  • [Presentation] Novel Thrombogenicity Examination of Whoel Blood: Total Thronbus-formation Analysis System in Dogs2017

    • Author(s)
      Tomoko Iwanaga, Shusaku Yamada, Ryuji Fukushima, Tomoka Nagasato, Ikuro Maruyama, Naoki Miura
    • Organizer
      2017 American College of Veterinary Internal Medicine Forum
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08054
  • [Presentation] 感染防御とその破綻のシステムバイオロジー2017

    • Author(s)
      丸山征郎
    • Organizer
      第13回九州小児免疫フォーラム
    • Place of Presentation
      ホテルセントラーザ博多(福岡県福岡市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15763
  • [Presentation] 救急患者体内の役者達:PAMPs/DAMPsそしてRAMPs2016

    • Author(s)
      丸山征郎
    • Organizer
      第20回日本救急医学会九州地方会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293385
  • [Presentation] Anti-inflammatory and anticoagulant roles of thrombomodulin in sepsis-associated DIC2016

    • Author(s)
      Takashi Ito, and Ikuro Maruyama
    • Organizer
      1st joint Meeting of ISFP and PA workshop
    • Place of Presentation
      日本平ホテル(静岡県静岡市)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05684
  • [Presentation] 救急患者体内の役者達:PAMPs/DAMPsそしてRAMPs2016

    • Author(s)
      丸山征郎
    • Organizer
      第20回日本救急医学会九州地方会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15763
  • [Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016

    • Author(s)
      古城 剛, 山口 宗一, 吉村 明子, 竹之内 和則, 伊藤 隆史, 清水 利昭, 大山 陽子, 郡山 豊泰, Sushil Panta, 松下 昌風, 丸山 征郎, 高嶋 博, 橋口 照人
    • Organizer
      第38回日本血栓止血学会学術集会
    • Place of Presentation
      奈良春日野国際フォーラム(奈良県奈良市)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-15K15196
  • [Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016

    • Author(s)
      古城 剛, 山口 宗一, 吉村 明子, 竹之内 和則, 伊藤 隆, 清水 利昭, 大山 陽子, 郡山 豊泰, Panta Sushil, 松下 昌風, 丸山 征郎, 高嶋 博, 橋口 照人
    • Organizer
      第63回日本臨床検査医学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-26293130
  • [Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016

    • Author(s)
      古城 剛、山口宗一、吉村明子、竹之内和則、伊藤隆史、清水利昭、大山陽子、郡山豊泰、Sushil Panta 、松下昌風、丸山征郎、髙嶋 博、橋口照人
    • Organizer
      第38回日本血栓止血学会学術集会
    • Place of Presentation
      奈良春日野国際フォーラム~I・RA・KA~(奈良県奈良市)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-16H05229
  • [Presentation] 血栓形成に関する新しい機序とトロンビンの役割2016

    • Author(s)
      丸山征郎
    • Organizer
      第120回日本循環器学会九州地方会
    • Place of Presentation
      ホルトホール大分(大分県大分市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K15763
  • [Presentation] 出血傾向を全血血栓形成観測システム(T-TAS)により確認できた犬の3例2016

    • Author(s)
      安川洋子、山田修作、河口貴恵、平尾大樹、橋本梨那、永里朋香、丸山征郎、三浦直樹、岩永朋子、福島隆治
    • Organizer
      第37回動物臨床医学年次大会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2016-11-18
    • Data Source
      KAKENHI-PROJECT-16K08054
  • [Presentation] 血栓形成に関する新しい機序とトロンビンの役割2016

    • Author(s)
      丸山征郎
    • Organizer
      第120回日本循環器学会九州地方会
    • Place of Presentation
      ホルトホール大分(大分県大分市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293385
  • [Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016

    • Author(s)
      古城 剛, 山口 宗一, 吉村 明子, 竹之内 和則, 伊藤 隆, 清水 利昭, 大山 陽子, 郡山 豊泰, Panta Sushil, 松下 昌風, 丸山 征郎, 高嶋 博, 橋口 照人
    • Organizer
      第63回日本臨床検査医学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-15K15196
  • [Presentation] Thrombin-thrombomodulin system in the hemostatic system and its clinical implication2016

    • Author(s)
      Ikuro Maruyama,and Takashi Ito
    • Organizer
      The 1st Joint Meeting of ISFP/PA Workshop
    • Place of Presentation
      日本平ホテル(静岡県静岡市)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15763
  • [Presentation] CalDAG-GEFI分子異常により血小板機能異常を呈した一症例2016

    • Author(s)
      古城 剛, 山口 宗一, 吉村 明子, 竹之内 和則, 伊藤 隆史, 清水 利昭, 大山 陽子, 郡山 豊泰, Sushil Panta, 松下 昌風, 丸山 征郎, 高嶋 博, 橋口 照人
    • Organizer
      第38回日本血栓止血学会学術集会
    • Place of Presentation
      奈良春日野国際フォーラム(奈良県奈良市)
    • Year and Date
      2016-06-16
    • Data Source
      KAKENHI-PROJECT-26293130
  • [Presentation] 細胞外ヒストンによる炎症性サイトカインIL-1β放出機構の解明2015

    • Author(s)
      大池加恵、勝野涼太、藤本靖真、安田哲、丸山征郎、菊池清志、川原幸一
    • Organizer
      西日本生理学会
    • Place of Presentation
      久留米
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26670793
  • [Presentation] 細胞外ヒストンにおけるIL-1β放出機構の解明2015

    • Author(s)
      大池加恵、勝野涼太、藤本靖真、安田 哲 丸山征郎、川原幸一
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26670793
  • [Presentation] 細胞外ヒストンによる炎症性サイトカインIL-1β放出機構の解明2015

    • Author(s)
      大池加恵、勝野涼太、藤本靖真、安田哲、丸山征郎、菊池清志、川原幸一
    • Organizer
      西日本生理学会
    • Place of Presentation
      久留米
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-26293387
  • [Presentation] 細胞外ヒストンにおけるIL-1β放出機構の解明2015

    • Author(s)
      大池加恵、勝野涼太、藤本靖真、安田 哲 丸山征郎、川原幸一
    • Organizer
      日本分子生物学会年会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26293387
  • [Presentation] Regulation of Danger Signals from HMGB1and Histones by Endothelial or Circulating Thrombomodulin2013

    • Author(s)
      Ikuro Maruyama
    • Organizer
      The Merinoff World Congress 2013 : HMGB1
    • Place of Presentation
      Manhasset, NY
    • Data Source
      KAKENHI-PROJECT-25670764
  • [Presentation] Massive thrombosis evoked by extracellular histones : Is it DIC?2013

    • Author(s)
      Takashi Ito, Mayumi Nakahara, and Ikuro Maruyama
    • Organizer
      59th Scientific and Standardization Committee Meeting of the ISTH 2013
    • Place of Presentation
      オランダ.
    • Data Source
      KAKENHI-PROJECT-25670763
  • [Presentation] Assay method of des-HMGB12013

    • Author(s)
      Ikuro Maruyama, Takashi Ito, Yoshio Azuma, Mayumi Nakahara, Teruto Hashiguchi, Shingo Yamada
    • Organizer
      N-terminus cleaved out HMGB1 by thrombin-thrombomodulin, and its clinical significance XXIVcongress of the ISTH
    • Place of Presentation
      Amsterdam, The Netherlands
    • Data Source
      KAKENHI-PROJECT-25670764
  • [Presentation] Assay method of des-HMGB1, N-terminus cleaved out HMGB1 by thrombinthrombomodulin, and its clinical significance2013

    • Author(s)
      Ikuro Maruyama, Takashi Ito, Yoshio Azuma, Mayumi Nakahara, Teruto Hashiguchi, Shingo Yamada
    • Organizer
      XXIVcongress of the ISTH
    • Place of Presentation
      Amsterdam, The Netherlands
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Presentation] Assay method of Des-HMGB1, N-terminus cleaved out HMGB1 by thrombin-thrombomodulin and its clinical significance2013

    • Author(s)
      kuro Maruyama, Takashi Ito, Shigo Yamada
    • Organizer
      XXIV Congress of the ISTH
    • Data Source
      KAKENHI-PROJECT-24659798
  • [Presentation] Regulation of Danger Signals from HMGB1and Histones by Endothelial or Circulating Thrombomodulin2013

    • Author(s)
      Ikuro Maruyama
    • Organizer
      The Merinoff World Congress 2013 : HMGB1
    • Place of Presentation
      Manhasset, NY
    • Data Source
      KAKENHI-PROJECT-23390412
  • [Presentation] イチゴエキスはHMGB1の放出を抑制する2013

    • Author(s)
      大池加恵、上村龍平、丸山征郎、川原幸一
    • Organizer
      2013年度日本生物高分子学会
    • Place of Presentation
      大阪
    • Year and Date
      2013-11-20
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Presentation] イチゴの新規機能 : HMGB1放出抑制2012

    • Author(s)
      上村龍平、大池加恵、丸山征郎、川原幸一
    • Organizer
      第85回生化学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-15
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Presentation] 内臓平滑筋 human VEGF-A 発現マウスにおける膵インスリン陽性細胞の構築変化2012

    • Author(s)
      竹之内和則、永里 朋香、清水 利明、丸山 征郎、橋口 照人
    • Organizer
      第59回日本臨床検査医学会学術集
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Presentation] イチゴの新規機能 : HMGB1放出抑制2012

    • Author(s)
      上村龍平、大池加恵、丸山征郎、川原幸一
    • Organizer
      第51回日本栄養・食糧学会近畿支部大会
    • Place of Presentation
      兵庫
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Presentation] 免疫B細胞発現VEGF-Aによるリンパ節リモデリングと免疫環境の機能的制2012

    • Author(s)
      橋口照人、伊藤隆史、SHRESTHA B、三浦直樹、丸山征郎
    • Organizer
      第34回日本血栓止血学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-22390179
  • [Presentation] イチゴの新規機能 : HMGB1放出抑制2012

    • Author(s)
      上村龍平、大池加恵、丸山征郎、川原幸一
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PROJECT-24659804
  • [Presentation] Recombinant thrombomodulin and HMGB12011

    • Author(s)
      Ito T, and Maruyama I.
    • Organizer
      American Heart Association Scientific Sessions 2011(Cardiovascular Seminar CVS. 705)
    • Place of Presentation
      米国オーランド
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-23890166
  • [Presentation] NSAIDs点眼による脈絡膜血管新生抑制2011

    • Author(s)
      吉永就正, 有村昇, 大塚寛樹, 竹之内和則, 貞村ゆかり, 野間聖, 川原幸一, 園田祥三, 橋口照人, 丸山征郎, 坂本泰二
    • Organizer
      第65回日本臨床眼科学会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2011-10-08
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] Nsaids Eye Drop As Anti-oxidant Treatment In Choroidal Neovascularization2011

    • Author(s)
      Narimasa Yoshinaga, Noboru Arimura, Shozo Sonoda, Kazunori Takenouchi, Yukari Sadamura, Satoshi Noma, Ko-ichi Kawahara, Teruto Hashiguchi, Ikuro Maruyama, Taiji Sakamoto
    • Organizer
      ARVO2011
    • Place of Presentation
      Fort Lauderdale・U. S. A
    • Year and Date
      2011-05-02
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] Nsaids Eye Drop As Anti-oxidant Treatment In Choroidal Neovascularization2011

    • Author(s)
      Narimasa Yoshinaga, Noboru Arimura, Shozo Sonoda, Kazunori Takenouchi, Yukari Sadamura, Satoshi Noma, Ko-ichi Kawahara, Teruto Hashiguchi, Ikuro Maruyama, Taiji Sakamoto
    • Organizer
      ARVO2011
    • Place of Presentation
      Fort Lauderdale・U.S.A
    • Year and Date
      2011-05-02
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] Endothelial function as an objective assessment tool of fatigue in healthy individuals2010

    • Author(s)
      Ohno Y, Hashiguchi T, Maenosono R, Yamashita H, Taira Y, Minowa K, Yamashita Y, Kato Y, Kawahara K, Maruyama I
    • Organizer
      ICOHN&ACOHN Joint Conference2010
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Presentation] HMGBIのトロンビン・トロンボモジュリンによる制御機構2009

    • Author(s)
      川原幸一, 伊藤隆史, 橋口照人, 丸山征郎
    • Organizer
      第12回日本異種移植研究会
    • Place of Presentation
      鹿児島
    • Year and Date
      2009-03-07
    • Data Source
      KAKENHI-PROJECT-17100007
  • [Presentation] Therapeutic strategy for circulating "bad" HMGB1 in septic shock.2009

    • Author(s)
      Maruyama I.
    • Organizer
      第2回HMGB1会議
    • Place of Presentation
      ハンブルグ(ドイツ)
    • Year and Date
      2009-09-25
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Presentation] 裂孔原性網膜剥離における硝子体中SDF-1とその他のサイトカイン2009

    • Author(s)
      大塚寛樹, 有村 昇, 山切啓太, 橋口照人, 丸山征郎
    • Organizer
      厚生労働省難治性疾患克服研究事業 網膜脈絡膜・視神経萎縮症調査研究班 平成20年度班会議
    • Place of Presentation
      名古屋市立大学(名古屋市)
    • Year and Date
      2009-01-17
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] 網膜剥離における High-mobility group box 1 protein の関与2009

    • Author(s)
      有村昇, 喜井裕哉, 橋口照人, 川原幸一, 中村誠, 園田恭志, 山切啓太, 大久保明子, 丸山征郎, 坂本泰二
    • Organizer
      第113回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2009-04-17
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] 網膜剥離における視細胞死とHigh-mobility group box 1 Protein2009

    • Author(s)
      有村 昇, 喜井裕哉, 橋口照人, 川原幸一, 中村 誠, 園田恭志, 山切啓太, 大久保明子, 丸山征郎, 坂本泰二
    • Organizer
      厚生労働省難治性疾患克服研究事業 網膜脈絡膜・視神経萎縮症調査研究班 平成20年度班会議
    • Place of Presentation
      名古屋市立大学(名古屋市)
    • Year and Date
      2009-01-17
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] Therapeutic strategy for circulating "bad" HMGB1 in septic shock2009

    • Author(s)
      Maruyama I
    • Organizer
      第2回HMGB1会議
    • Place of Presentation
      ハンブルグ(ドイツ)
    • Year and Date
      2009-09-25
    • Data Source
      KAKENHI-PROJECT-20390274
  • [Presentation] Concentration of Cytokines After Intravitreous Injection of Bevacizumab or Triamcinolone.2008

    • Author(s)
      Otsuka H, Arimura N, Ki-I Y, Yamakiri K, Doi N, Hashiguchi T, Maruyama I, Sakamoto T.
    • Organizer
      The Association for Reseach in Vision and ophthalmology.
    • Place of Presentation
      Fort Lauderdale, U. S. A
    • Data Source
      KAKENHI-PROJECT-20390450
  • [Presentation] ヒトリンパ細胞はブタ内皮細胞を標的・活性化しHigh Mobility Group Box 1 (HMGB1)を発現誘導する2008

    • Author(s)
      川原幸一、高尾尊身、丸山征郎
    • Organizer
      第11回異種移植研究会
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-23
    • Data Source
      KAKENHI-PROJECT-17100007
  • [Presentation] ヒトリンパ球細胞はブタ内皮細胞を標的・活性化しHMGB1を発現誘導する2008

    • Author(s)
      川原幸一、瀬戸山健太郎、菊池清志、上村亮三、三浦直樹、森元陽子、高尾尊身、橋口照人、丸山征郎
    • Organizer
      第11回日本異種移植研究会
    • Place of Presentation
      国立循環器病センター
    • Year and Date
      2008-02-23
    • Data Source
      KAKENHI-PROJECT-17100007
  • [Presentation] RH-PAT(Reactive hyperemia-peripheral arterial tonometry)解析による血管内皮細胞機能に与える影響因子の多様性2008

    • Author(s)
      大野佳子, 前之園隆一, 橋口照人, 丸山征郎, 他
    • Organizer
      第19回九州血管血栓フォーラム
    • Place of Presentation
      鹿児島大学 鶴陵会館(鹿児島市)
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-19650184
  • [Presentation] Degradation of non-hemostatic molecules in the state of DIC/MOF2008

    • Author(s)
      橋口照人, 川原幸一, 丸山征郎, 李良子, 田中憲次
    • Organizer
      第12回エンドトキシン血症救命治療研究会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Presentation] RH-PATによる血管内皮細胞機能の評価第3報-内皮細胞機能障害因子, 性差との関連解析-.2008

    • Author(s)
      前之園隆一, 大野佳子, 橋口照人, 丸山征郎, 他
    • Organizer
      第19回九州血管血栓フォーラム
    • Place of Presentation
      鹿児島大学 鶴陵会館(鹿児島市)
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-19650184
  • [Presentation] DIC/MOFにおける非止血関連分子の崩壊2008

    • Author(s)
      橋口照人, 李良子, 田中憲次, 丸山征郎
    • Organizer
      日本血栓止血学会学術標準化委員会(SSC)シンポジウム
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Presentation] DIC/MOFにおける生体内蛋白分解の網羅的解析2007

    • Author(s)
      橋口照人, 川原幸一, 丸山征郎, 李良子, 田中憲次
    • Organizer
      第13回日本エンドトキシン研究会
    • Place of Presentation
      鹿児島
    • Data Source
      KAKENHI-PROJECT-19390156
  • [Presentation] Reactive hyperemia peripheral arterial tonometory (RH-PAT)を用いた血管内皮細胞機能評価の臨床応用についての研究2007

    • Author(s)
      前之園隆一, 大野佳子, 橋口照人, 黒木辰雄, 丸山征郎
    • Organizer
      第7回臨床血液脈波研究会
    • Place of Presentation
      大阪市
    • Year and Date
      2007-06-02
    • Data Source
      KAKENHI-PROJECT-19650184
  • [Presentation] ヒトリンパ細胞はブタ内皮細胞を標的・活性化しHigh Mobility Group Box 1 (HMGB1)を発現誘導する2007

    • Author(s)
      川原幸一、高尾尊身、丸山征郎
    • Organizer
      第10回日本異種移植研究会
    • Place of Presentation
      東京
    • Year and Date
      2007-03-10
    • Data Source
      KAKENHI-PROJECT-17100007
  • [Presentation] Reactive hyperemia peripheral arterial tonometory (RH-PAT)による血管内皮細胞機能の評価-内皮機能障害因子との関連の解析2007

    • Author(s)
      前之園隆一, 大野佳子, 橋口照人, 黒木辰雄, 丸山征郎
    • Organizer
      第5回日本予防医学学会学術集会
    • Place of Presentation
      指宿市
    • Year and Date
      2007-11-24
    • Data Source
      KAKENHI-PROJECT-19650184
  • [Presentation] 健常人に対するRH-PAT(Reactive hyperemia-peripheral artery tonometry)による血管内皮細胞機能の検証2007

    • Author(s)
      大野佳子, 前之園隆一, 橋口照人, 丸山征郎, 加藤裕子
    • Organizer
      第5回日本予防医学学会学術集会
    • Place of Presentation
      指宿市
    • Year and Date
      2007-11-24
    • Data Source
      KAKENHI-PROJECT-19650184
  • [Presentation] Degradation of homeostatic molecules in the state of DIC/MOF2007

    • Author(s)
      橋口照人、李 良子、田中憲次、丸山征郎
    • Organizer
      第30回日本血栓止血学会学術集会
    • Place of Presentation
      三重県
    • Year and Date
      2007-11-17
    • Data Source
      KAKENHI-PROJECT-19390156
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