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Shimada Ichio  嶋田 一夫

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SHIMADA Ichio  嶋田 一夫

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Researcher Number 70196476
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームディレクター
Affiliation (based on the past Project Information) *help 2019 – 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, チームリーダー
2016 – 2018: 東京大学, 大学院薬学系研究科(薬学部), 教授
2014 – 2015: 東京大学, 大学院薬学系研究科, 教授
2009 – 2015: 東京大学, 薬学研究科(研究院), 教授
2013: 東京大学, 大学院薬学系研究科 … More
2007 – 2011: The University of Tokyo, 大学院・薬学系研究科, 教授
2007 – 2008: 東京大学, 大学院・薬学系, 教授
2006: The University of Tokyo, Graduate School of Pharmaceutical Sciences, Professor, 大学院薬学研究科, 教授
2006: 東京大学, 大学院薬学系研究科, 教授
1998 – 2005: Graduate School of Pharmaceutical Sciences, University of Tokyo, Professor, 大学院・薬学系研究科, 教授
2001: Graduate School of Pharmaceutical sciences, The University of Tokyo, Professor, 大学院・薬学研究科, 教授
1998: 東京大学, 大学院薬学研究科, 教授
1994 – 1997: The Univ.of Tokyo, Fac.of Pharm.Sc., Professor, 薬学部, 教授
1991 – 1993: 東京大学, 薬学部, 助教授
1990: 東京大学, 薬学部, 講師 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Physical pharmacy / Complex systems / Biological Sciences
Except Principal Investigator
Biological Sciences / Physical pharmacy / Science and Engineering / Chemistry / Biological pharmacy / Structural biochemistry
Keywords
Principal Investigator
NMR / 構造生物学 / 核磁気共鳴法 / 相互作用 / 交差飽和法 / ケモカイン / HIV / 抗体 / 動的立体構造 / 膜タンパク質 … More / 転移交差飽和法 / 立体構造 / Fv / 安定同位体標識 / 分子認識 / イオンチャネル / タンパク・タンパク相互作用 / タンパク-タンパク相互作用 / 抗原認識 / CPD photolyase / ハイスループット / 損傷DNA / 触媒抗体 / GPCR / 動的構造 / 動的構造平衡 / 多剤耐性トランスポーター / Gタンパク質共役型受容体 / interaction / membrane Protein / transferred cross saturation / cross-saturation / Stable-isotope labeling / 安定同位体認識法 / 安定同位体 / 相互作用解析 / 膜蛋白質 / 移転交差飽和法 / 安定同位体標識法 / Drug Design / Gating Modifier / Ion Channel / Structural Biology / Nuclear Magnetic Resonance / ブロッカー / ゲーディングモディファイアー / 創薬 / ゲーテリング変調剤 / KINETIC ANALYSIS / AFFINITY MATURATION / ANTIBODY / 親和性 / 速度論解析 / 親和力マチュレーション / dynamical structure / protein-protein interaction / antigen recognition / antibody / NVR / タンパクタンパク相互作用 / Dynamics / Recognition / Antibodies / 安定同位体標式 / 動的 / 認識 / 構造平衡 / 過渡的複合体 / ケミカルバイオロジ / ケミカル・バイオロジ / X線結晶構造解析 / ケミカルバイオロジー / 一分子計測学 / X線結晶構造解析 / 領域とりまとめ / 分子間相互作用 / 光回復酵素 / 多次元NMR法 / ケモカイン受容体 / タンパク質複合体 / FAD / ゲノム / photolyase / 紫外線 / 核酸 / 遷移状態 / CDR grafting / エステル加水分解反応 / ダイナミックス … More
Except Principal Investigator
NMR / 構造生物学 / 相互作用解析 / 蛋白質 / X線結晶構造解析 / 核磁気共鳴法 / 紫外線損傷DNA / 抗原抗体反応 / 抗体 / Grb2 / SH3 / Vav / S-II / Biosensor / 電位依存性イオンチャネル / 分子認識 / 膜蛋白質 / ユビキチン / 不均一系 / 超分子 / 第二補酵素 / 高熱菌 / (6-4)photolyase / CPD-photolyase / CPD / 光修復酵素 / GPCR / シグナル伝達 / 膜タンパク質 / ヒドロペルオキシド / α-リノレン酸 / ピ-マン / ダイズ / ヘム鉄 / 緑の香り / リポキシゲナーゼ / 蛋白質-蛋白質相互作用 / 動的構造平衡 / 蛋白質ー蛋白質相互作用 / 蛋白質-蛋白質複合体 / tertiary structure IP3 / praline rich region / Neurop / PB2 / PBI / 好中級活性酸素発生系 / タイトジャンクション / N-WASP / Rho / 多核体病ウィルス / バキュロウィルス / Grb2-cSH3 / PRR / Vav-nSH3 / PTB様ドメイン / IP3 / radixin / 蛋白質立体構造 / PRR領域 / X-ray crystallography / Single-chain antibody / Molecular recognition / UV-damaged DNA / X線結晶学 / 合成DNA / 抗光損傷DNA抗体 / 光損傷DNA / 1本鎖抗体 / Transcriptional factor / Crystallin gene / Polycomb genes / Transgenics / B cell / Immunological tolerance / T cell / 転写因子 / 有機リン系農薬センサー / 水晶体特異的遺伝子発現 / ポリコ-ム遺伝子 / 発生工学 / B細胞 / 免疫寛容 / T細胞 / RT-PCR method / domain structure / Transcriptional regulation / Transcription elongation factors / Interaction between DNA and transcription factors / Basal transcription factor / Transcriptional regulatory factor / TFIIB / RT-PCR法 / ドメイン構造 / 転写調節 / 転写伸長因子 / 相互作用 / 転写基本因子 / 転写調節因子 / X-ray Crystallography / Chemical Synthesis / Solid-state NMR / Protein Nucleic Acid Interaction / Analytical Method / 3-dimensional Structure / Protein / 化学合成 / 固体NMR / 蛋白質・核酸相互作用 / 解析法 / 高次構造 / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 細胞周期 / 温度感受性突然変異体 / ATPase / 免疫病 / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / 薬学 / 分子モーター / 電子顕微鏡 / モーター蛋白質 / クライオ電顕 / rHDL / 膜電位依存性 / 電位依存性K+チャネル / 構造変化 / SS-locking / イオンゲート / イオンチャネル / 分子認識様式 / gating modifier toxin / 電位センサードメイン / 複合体構造 / 安定同位体標識 / 常磁性 / (6-4) photolyase / 交差飽和法 / レクチン / 糖鎖 / mRNA分解酵素 / ポリA結合蛋白質(PABP) / 翻訳終結因子eRF3 / mRNA分解 / ポリA結合タンパク質 / Budded virus / HIV / CCR5 / RANTES / ケモカイン受容体 / ケモカイン / 転移交差飽和法 / 分子間相互作用 / ソフトな相互作用 / 核磁気共鳴法(NMR) / 物質輸送 / ソフトな分子間相互作用 / 生命秩序 / 膜インターフェイス / ヒドロペルオキシライエ-ス / ヒドロペルオキシドライエ-マ Less
  • Research Projects

    (51 results)
  • Research Products

    (429 results)
  • Co-Researchers

    (147 People)
  •  In situ functional analyses of membrane proteins by NMRPrincipal Investigator

    • Principal Investigator
      Shimada Ichio
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
      The University of Tokyo
  •  Development of methods for studying conformational dynamics of ubiquitin-ubiquitin binding protein complex

    • Principal Investigator
      Ueda Takumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  Structural elucidation of the mechanism underlying biased signaling of GPCRs

    • Principal Investigator
      Ueda Takumi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  Voltage-dependent structural changes and functinal mechanism of voltage-dependent ion channels

    • Principal Investigator
      OSAWA Masanori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  Affinity regulation mechanism of microtubule-binding domain of cytoplasmic dynein

    • Principal Investigator
      NISHIDA Noritaka
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo
  •  Integrative understanding of biological processes mediated by transient macromolecul ar complexes; New technology for visualizing physiologically metastable statesPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Structural analyses of the metastable ligand-receptor interactionsPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Motional linkage between voltage sensor and ion gate in voltage-dependent ion channels

    • Principal Investigator
      OSAWA Masanori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  Integrative understanding of biological processes mediated by transient macromolecular complexes; New technology for visualizing physiologically metastable states.Area Organizer

    • Area Organizer
      SHIMADA Ichio
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  不均一系超分子における分子認識機構を解明するNMR戦略の開発

    • Principal Investigator
      大澤 匡範
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Development of an NMR strategy for the structural analysis of themolecular recognition in the membrane protein complex in lipidbilayers

    • Principal Investigator
      OSAWA Masanori
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNA修復機構の構造生物学的解析

    • Principal Investigator
      寺沢 宏明
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  NMRを用いた生体機能分子-標的蛋白質複合体の相互作用解析法の開発

    • Principal Investigator
      坂倉 正義
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  不均一系超分子における分子認識機構を解明するNMR戦略の開発

    • Principal Investigator
      大澤 匡範
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNA修復機構の構造生物学的解析

    • Principal Investigator
      寺沢 宏明
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  翻訳終結と共役したmRNA分解制御機構の構造生物学的解明

    • Principal Investigator
      OSAWA Masanori
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  NMRを用いた生体機能分子・標的蛋白質複合体の相互作用解析法の開発

    • Principal Investigator
      坂倉 正義
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      The University of Tokyo
  •  不均一系超分子における分子認識機構を解明するNMR戦略の開発

    • Principal Investigator
      大澤 匡範
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HIV感染機構の解明:ケモカイン受容体・リガンド相互作用の構造生物学的研究

    • Principal Investigator
      寺沢 宏明
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  原子レベルでの病態解明に向けたハイスループットな分子間相互作用解析法の開発Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HIV感染機構の解明:ケモカイン受容体・リガンド相互作用の構造生物学的研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNA修復機構の構造生物学的解析Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Molecular soft interactions regulating membrane-interface activities in living systems

    • Principal Investigator
      AKUTSU Hideo
    • Project Period (FY)
      2003 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Development of NMR methodology for soft interaction of proteinsPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      2003 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  原子レベルでの病態解明に向けたハイスループットな分子間相互作用解析法の開発Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HIV感染機構の解明:ケモカイン受容体・リガンド相互作用の構造生物学的研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNA修復機構の構造生物学的解析Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Nobel strategy of structural biology for investigation of membrane proteins-ligandsPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  原子レベルでの病態解明に向けたハイスループットなタンパク質相互作用解析法の開発Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNAの構造生物学的解析Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  HIV感染機構の解明:ケモカイン受容体・リガンド相互作用の構造生物学的研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  触媒抗体の触媒機能発現メカニズムの解明と活性向上を目指した改変Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  NMRを用いた紫外線損傷DNAの構造生物学的研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  触媒抗体の触媒機能発現メカニズムの解明と活性向上を目指した改変Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  がん診断治療を目指した免疫グロブリンFvフラグメントの構造生物学的研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Structural Biological Study of Ion Channel Blockers and Development of Drug DesignPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  Protein-protein interaction in intracellular signal transduction

    • Principal Investigator
      INAGAKI Fuyuhiko
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Hokkaido University
      Tokyo Metropolitan Organization for Medical Research
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University, School of Medicine
  •  Elucidation of recognition mechanisms of antibodies specific for nucleic aicd derivatives

    • Principal Investigator
      OHTSUKA Eiko
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Chemistry
    • Research Institution
      Hokkaido University
  •  "緑の香り"発現酵素-基質複合体(超分子)の精密構造とその形成機構の解明

    • Principal Investigator
      畑中 顕和
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of East Asia
  •  NMRを用いたタンパク質分子に内在するダイナミックスの研究Principal Investigator

    • Principal Investigator
      嶋田 一夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis of the function of transcription clongation factor S-II family based on the structural analyzes

    • Principal Investigator
      HORIKOSHI Masami
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      The University of Tokyo
  •  Elucidation of the structural mechanisms of the affinity maturation in the immune response of anti-NP antibodies.Principal Investigator

    • Principal Investigator
      TAKAHASHI Hideo, 嶋田 一夫
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  “緑の香り"発現酵素-基質複合体(超分子)の精密構造とその形成機構の解明

    • Principal Investigator
      畑中 顯和
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of East Asia
  •  Development of Novel Methods for Structural Analyses of Proteins

    • Principal Investigator
      AIMOTO Saburo
    • Project Period (FY)
      1994 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  抗体工学に関する基礎的・応用的研究

    • Principal Investigator
      荒田 洋治
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Development of dynamical structural analysis for the active site of multi functional proteinsPrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokyo
  •  抗体工学に関する基礎的・応用的研究

    • Principal Investigator
      荒田 洋治
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Molecular Recognition and Signal Transduction in AntibodiePrincipal Investigator

    • Principal Investigator
      SHIMADA Ichio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      University of Tokyo
  •  抗体工学に関する基礎的・応用的研究

    • Principal Investigator
      荒田 洋治
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Book Patent

  • [Book] Large Protein Complexes Revealed by Solution-State NMR: G Proteins and G Protein-Activated Inwardly Rectifying Potassium Ion Channel2013

    • Author(s)
      Osawa M., Mase Y., Yokogawa M., Takeuchi K. and Shimada I.
    • Total Pages
      32
    • Publisher
      Royal Society of Chemistry
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Book] 【試料分析講座】「蛋白質の分析」, 分析化学会2012

    • Author(s)
      大澤匡範、今井駿輔、嶋田一夫.
    • Total Pages
      34
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Book] Encyclopedia of Biophysics, GCR. Roberts (ed.)2011

    • Author(s)
      Ichio Shimada
    • Total Pages
      1
    • Publisher
      Springer-Verlag Berlin Heidelberg Ichio Sliimada
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Book] Encyclopedia of Biophysics(GCR.Roberts (ed.))2011

    • Author(s)
      Ichio Shimada
    • Total Pages
      1
    • Publisher
      Springer-Verlag Berlin Heidelberg Ichio Shimada
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Book] 生体の科学(不溶性の細胞外マトリックスとの相互作用を解明する新しいNMR測定法)2008

    • Author(s)
      西田紀貴・嶋田一夫
    • Data Source
      KAKENHI-PROJECT-15083101
  • [Book] コラーゲン結合タンパク質を介した生命プロセスの活性化機構2008

    • Author(s)
      西田紀貴、嶋田一夫
    • Publisher
      生化学
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Book] NMRによるソフトな分子間相互作用解析法の開発2008

    • Author(s)
      松本昌彦、上田卓見、嶋田一夫
    • Publisher
      生化学
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Book] 交換系利用NMRによるリガンド分子の標的分子結合状態の構造解析 高橋栄夫・嶋田一夫2007

    • Author(s)
      高橋栄夫、嶋田一夫
    • Publisher
      蛋白質・核酸・酵素
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Book] 「等温滴定型カロリメトリー(ITC)-熱量測定による相互作用の定量的解析-」実験医学別冊「生命科学のための機器分析実験ハンドブック2007

    • Author(s)
      大澤匡範、嶋田一夫
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Activation mechanism of the μ-opioid receptor by an allosteric modulator.2022

    • Author(s)
      Kaneko S, Imai S, Asao N, Kofuku Y, Ueda T, Shimada I.
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 119 Issue: 16

    • DOI

      10.1073/pnas.2121918119

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-23K21289
  • [Journal Article] Function-related dynamics of GPCRs2022

    • Author(s)
      Ueda Takumi、Imai Shunsuke、Shimada Ichio
    • Journal Title

      Journal of Magnetic Resonance

      Volume: 336 Pages: 107164-107164

    • DOI

      10.1016/j.jmr.2022.107164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02619, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375
  • [Journal Article] Conformational Plasticity of Cyclic Ras‐Inhibitor Peptides Defines Cell Permeabilization Activity2021

    • Author(s)
      Takeuchi Koh、Misaki Imai、Tokunaga Yuji、Fujisaki Miwa、Kamoshida Hajime、Takizawa Takeshi、Hanzawa Hiroyuki、Shimada Ichio
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 60 Issue: 12 Pages: 6567-6572

    • DOI

      10.1002/anie.202016647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21494, KAKENHI-PROJECT-17H06097
  • [Journal Article] 分子夾雑系が変調するタンパク質の構造と機能2021

    • Author(s)
      趙慶慈、嶋田一夫、西田紀貴
    • Journal Title

      月刊「細胞」

      Volume: 53 Pages: 352-355

    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] NMR法を用いた中分子環状ペプチドの立体構造解析と細胞内移行活性の理2021

    • Author(s)
      竹内恒、嶋田一夫
    • Journal Title

      Pharm Stage

      Volume: 21 Pages: 8-8

    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] Mechanism of hERG inhibition by gating-modifier toxin, APETx1, deduced by functional characterization2021

    • Author(s)
      Matsumura Kazuki、Shimomura Takushi、Kubo Yoshihiro、Oka Takayuki、Kobayashi Naohiro、Imai Shunsuke、Yanase Naomi、Akimoto Madoka、Fukuda Masahiro、Yokogawa Mariko、Ikeda Kazuyoshi、Kurita Jun-ichi、Nishimura Yoshifumi、Shimada Ichio、Osawa Masanori
    • Journal Title

      BMC Molecular and Cell Biology

      Volume: 22 Issue: 1 Pages: 1-16

    • DOI

      10.1186/s12860-020-00337-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07284, KAKENHI-PUBLICLY-19H04973, KAKENHI-PUBLICLY-20H05449, KAKENHI-PROJECT-20H03424, KAKENHI-PROJECT-18K06152, KAKENHI-PROJECT-18K06606, KAKENHI-PROJECT-17H06097
  • [Journal Article] Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR2021

    • Author(s)
      Takeuchi Koh、Kofuku Yutaka、Imai Shunsuke、Ueda Takumi、Tokunaga Yuji、Toyama Yuki、Shiraishi Yutaro、Shimada Ichio
    • Journal Title

      Membranes

      Volume: 11 Issue: 8 Pages: 604-604

    • DOI

      10.3390/membranes11080604

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21494, KAKENHI-PUBLICLY-20H04722, KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-21H02619, KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-20H03378, KAKENHI-PROJECT-23K21289
  • [Journal Article] Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR2021

    • Author(s)
      Shiraishi Yutaro、Kofuku Yutaka、Ueda Takumi、Pandey Shubhi、Dwivedi-Agnihotri Hemlata、Shukla Arun K.、Shimada Ichio
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 7158-7158

    • DOI

      10.1038/s41467-021-27482-3

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21473, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-21H05509, KAKENHI-PROJECT-20H03375, KAKENHI-PROJECT-23K21289
  • [Journal Article] Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS2020

    • Author(s)
      Zhao Qingci、Fujimiya Ryu、Kubo Satoshi、Marshall Christopher B.、Ikura Mitsuhiko、Shimada Ichio、Nishida Noritaka
    • Journal Title

      Cell Reports

      Volume: 32 Issue: 8 Pages: 108074-108074

    • DOI

      10.1016/j.celrep.2020.108074

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-20H04693, KAKENHI-PROJECT-20J14841, KAKENHI-PROJECT-17H06097
  • [Journal Article] Structural basis for two-way communication between dynein and microtubules2020

    • Author(s)
      Nishida Noritaka、Komori Yuta、Takarada Osamu、Watanabe Atsushi、Tamura Satoko、Kubo Satoshi、Shimada Ichio、Kikkawa Masahide
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 1038-1038

    • DOI

      10.1038/s41467-020-14842-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] Structural equilibrium underlying ligand-dependent activation of b2-adrenoreceptor2020

    • Author(s)
      Shunsuke Imai, Tomoki Yokomizo, Yutaka Kofuku, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
    • Journal Title

      Nature Chemical Biology

      Volume: 16 Issue: 4 Pages: 430-439

    • DOI

      10.1038/s41589-019-0457-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04946, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-20H03375
  • [Journal Article] In situ structural biology using in-cell NMR2020

    • Author(s)
      Nishida Noritaka、Ito Yutaka、Shimada Ichio
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - General Subjects

      Volume: 1864 Issue: 2 Pages: 129364-129364

    • DOI

      10.1016/j.bbagen.2019.05.007

    • Peer Reviewed
    • Data Source
      KAKENHI-WRAPUP-19H05452, KAKENHI-PLANNED-19H05773, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-19H05645
  • [Journal Article] Activation of adenosine A2A receptor by lipids from docosahexaenoic acid revealed by NMR2020

    • Author(s)
      Takuya Mizumura, Keita Kondo, Masatoshi Kurita, Yutaka Kofuku, Mei Natsume, Shunsuke Imai, Yutaro Shiraishi, Takumi Ueda, Ichio Shimada
    • Journal Title

      Science Advances

      Volume: 6 Issue: 12

    • DOI

      10.1126/sciadv.aay8544

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04946, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-20H03375
  • [Journal Article] Structural Fingerprints of an Intact Monoclonal Antibody Acquired under Formulated Storage Conditions via 15N Direct Detection Nuclear Magnetic Resonance2020

    • Author(s)
      Tokunaga Yuji、Takeuchi Koh、Okude Junya、Ori Kazutomo、Torizawa Takuya、Shimada Ichio
    • Journal Title

      Journal of Medicinal Chemistry

      Volume: - Issue: 10 Pages: 5360-5366

    • DOI

      10.1021/acs.jmedchem.0c00231

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07040, KAKENHI-PROJECT-18K19415, KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-17H06097
  • [Journal Article] Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties2020

    • Author(s)
      Yuya Terashima, Etsuko Toda, Kouji Matsushima et al.
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 1-16

    • DOI

      10.1038/s41467-020-14338-5

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15716, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-17K08241, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-18K06991
  • [Journal Article] Conformational equilibrium shift underlies altered K+ channel gating as revealed by NMR2020

    • Author(s)
      Iwahashi Yuta、Toyama Yuki、Imai Shunsuke、Itoh Hiroaki、Osawa Masanori、Inoue Masayuki、Shimada Ichio
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 5168-5168

    • DOI

      10.1038/s41467-020-19005-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-19K15704, KAKENHI-PROJECT-17H06097
  • [Journal Article] Targeting the cryptic sites: NMR-based strategy to improve protein druggability by controlling the conformational equilibrium2020

    • Author(s)
      Mizukoshi Yumiko、Takeuchi Koh、Tokunaga Yuji、Matsuo Hitomi、Imai Misaki、Fujisaki Miwa、Kamoshida Hajime、Takizawa Takeshi、Hanzawa Hiroyuki、Shimada Ichio
    • Journal Title

      Science Advances

      Volume: 6 Issue: 40

    • DOI

      10.1126/sciadv.abd0480

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-20H04722, KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-20H03378, KAKENHI-PROJECT-17H06097
  • [Journal Article] Conformational equilibrium defines the variable induction of the multidrug-binding transcriptional repressor QacR2019

    • Author(s)
      Koh Takeuchi, Misaki Imai, and Ichio Shimada
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 116 Issue: 40 Pages: 19963-19972

    • DOI

      10.1073/pnas.1906129116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-17H06097
  • [Journal Article] 夾雑系の構造生物学2019

    • Author(s)
      西田紀貴、嶋田一夫
    • Journal Title

      化学と工業

      Volume: 72 Pages: 404-406

    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] NMR 解析の最前線:分子間相互作用と動的構造2019

    • Author(s)
      上田卓見、嶋田一夫
    • Journal Title

      月刊細胞

      Volume: 51 Pages: 596-599

    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel2019

    • Author(s)
      Kano Hanaho、Toyama Yuki、Imai Shunsuke、Iwahashi Yuta、Mase Yoko、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 1-13

    • DOI

      10.1038/s41467-019-10038-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06606, KAKENHI-PUBLICLY-18H04679, KAKENHI-PUBLICLY-19H04973, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-17H06097
  • [Journal Article] Frequency selective coherence transfer NMR spectroscopy to study the structural dynamics of high molecular weight proteins2019

    • Author(s)
      Toyama Yuki、Shimada Ichio
    • Journal Title

      Journal of Magnetic Resonance

      Volume: 304 Pages: 62-77

    • DOI

      10.1016/j.jmr.2019.05.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] Decreased conformational stability in the oncogenic N92I mutant of Ras-related C3 botulinum toxin substrate 12019

    • Author(s)
      Toyama Y, Kontani K, Katada T, Shimada I.
    • Journal Title

      Sci. Adv.

      Volume: 5 Issue: 8

    • DOI

      10.1126/sciadv.aax1595

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07351, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-17H03981
  • [Journal Article] Function-related conformational dynamics of G protein-coupled receptors revealed by NMR2019

    • Author(s)
      Takumi Ueda, Yutaka Kofuku, Junya Okude, Shunsuke Imai, Yutaro Shiraishi, Ichio Shimada
    • Journal Title

      Biophysical Reviews

      Volume: 11 Issue: 3 Pages: 409-418

    • DOI

      10.1007/s12551-019-00539-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H06097
  • [Journal Article] NMR Studies of Function-related Conformational Equilibria of GPCRs2019

    • Author(s)
      上田卓見、嶋田一夫
    • Journal Title

      Seibutsu Butsuri

      Volume: 59 Issue: 4 Pages: 181-187

    • DOI

      10.2142/biophys.59.181

    • NAID

      130007683541

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04540, KAKENHI-PUBLICLY-19H04951, KAKENHI-PROJECT-17H06097
  • [Journal Article] Conformational landscape alternations promote oncogenic activities of Ras-related C3 botulinum toxin substrate 1 as revealed by NMR2019

    • Author(s)
      Toyama Yuki、Kontani Kenji、Katada Toshiaki、Shimada Ichio
    • Journal Title

      Science Advances

      Volume: 5 Issue: 3

    • DOI

      10.1126/sciadv.aav8945

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07351, KAKENHI-PROJECT-17H03981, KAKENHI-PROJECT-17H06097
  • [Journal Article] Phosphorylation-induced conformation of β2-adrenoceptor related to arrestin recruitment revealed by NMR2018

    • Author(s)
      Yutaro Shiraishi, Mei Natsume, Yutaka Kofuku, Shunsuke Imai, Kunio Nakata, Toshimi Mizukoshi, Takumi Ueda, Hideo Iwai, Ichio Shimada
    • Journal Title

      Nature Communications

      Volume: 9 Issue: 1 Pages: 164-164

    • DOI

      10.1038/s41467-017-02632-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01353, KAKENHI-PUBLICLY-16H01531, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17J11420
  • [Journal Article] Endogenous Membrane Receptor Labeling by Reactive Cytokines and Growth Factors to Chase Their Dynamics in Live Cells2018

    • Author(s)
      Takaoka Yousuke、Uchinomiya Shohei、Kobayashi Daichi、Endo Masataka、Hayashi Takahiro、Fukuyama Yoshiaki、Hayasaka Haruko、Miyasaka Masayuki、Ueda Takumi、Shimada Ichio、Hamachi Itaru
    • Journal Title

      Chem

      Volume: 4 Issue: 6 Pages: 1451-1464

    • DOI

      10.1016/j.chempr.2018.03.021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08481, KAKENHI-PLANNED-17H06348, KAKENHI-PUBLICLY-18H04540, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097
  • [Journal Article] Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif2018

    • Author(s)
      Sugiki Toshihiko、Egawa Daichi、Kumagai Keigo、Kojima Chojiro、Fujiwara Toshimichi、Takeuchi Koh、Shimada Ichio、Hanada Kentaro、Takahashi Hideo
    • Journal Title

      Journal of Biological Chemistry

      Volume: 293 Issue: 28 Pages: 11206-11217

    • DOI

      10.1074/jbc.ra118.002465

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06649, KAKENHI-PUBLICLY-17H05836, KAKENHI-PUBLICLY-17H05873, KAKENHI-PLANNED-17H06417, KAKENHI-PUBLICLY-18H04626, KAKENHI-PROJECT-18H02393, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-17H03641
  • [Journal Article] GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures2018

    • Author(s)
      Shimada Ichio、Ueda Takumi、Kofuku Yutaka、Eddy Matthew T.、Wuthrich Kurt
    • Journal Title

      Nature Reviews Drug Discovery

      Volume: 18 Issue: 1 Pages: 59-82

    • DOI

      10.1038/nrd.2018.180

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04540, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097
  • [Journal Article] Structural basis for the ethanol action on G-protein?activated inwardly rectifying potassium channel 1 revealed by NMR spectroscopy2018

    • Author(s)
      Toyama Yuki、Kano Hanaho、Mase Yoko、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 115 Issue: 15 Pages: 3858-3863

    • DOI

      10.1073/pnas.1722257115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-18J13147
  • [Journal Article] Characterization of the multimeric structure of poly(A)-binding protein on a poly(A) tail2018

    • Author(s)
      Sawazaki Ryoichi、Imai Shunsuke、Yokogawa Mariko、Hosoda Nao、Hoshino Shin-ichi、Mio Muneyo、Mio Kazuhiro、Shimada Ichio、Osawa Masanori
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 1455-1455

    • DOI

      10.1038/s41598-018-19659-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PUBLICLY-17H05539, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-17H03635
  • [Journal Article] Application of C-terminal 7-azabicyclo[2.2.1]heptane to stabilize β?strand-like extended conformation of a neighboring α-amino acid2018

    • Author(s)
      Luhan Zhai  et al
    • Journal Title

      J. Org. Chem.,

      Volume: 83 Issue: 21 Pages: 13063-13079

    • DOI

      10.1021/acs.joc.8b01756

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02552, KAKENHI-PROJECT-16K08157, KAKENHI-PROJECT-17H06097
  • [Journal Article] Balanced Regulation of Redox Status of Intracellular Thioredoxin Revealed by in-Cell NMR2018

    • Author(s)
      Mochizuki Ayano、Saso Arata、Zhao Qingci、Kubo Satoshi、Nishida Noritaka、Shimada Ichio
    • Journal Title

      Journal of the American Chemical Society (selected as JACS Spotlights)

      Volume: 140 Issue: 10 Pages: 3784-3790

    • DOI

      10.1021/jacs.8b00426

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PLANNED-26119005
  • [Journal Article] Deuteration and Selective Labeling of Alanine Methyl Groups of β 2-Adrenergic Receptor Expressed in a Baculovirus-Insect Cell Expression System2018

    • Author(s)
      Yutaka Kofuku, Tomoki Yokomizo, Shunsuke Imai, Yutaro Shiraishi, Mei Natsume, Hiroaki Itoh, Masayuki Inoue, Kunio Nakata, Shunsuke Igarashi, Hideyuki Yamaguchi, Toshimi Mizukoshi, Ei-Ichiro Suzuki, Takumi Ueda, Ichio Shimada
    • Journal Title

      Journal of Biomolecular NMR

      Volume: 印刷中 Issue: 3 Pages: 185-192

    • DOI

      10.1007/s10858-018-0174-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17K15421, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01353, KAKENHI-PUBLICLY-16H01531, KAKENHI-PROJECT-17H06110, KAKENHI-PROJECT-17H04999, KAKENHI-PROJECT-17J11420, KAKENHI-PUBLICLY-18H04540
  • [Journal Article] Functional roles of Mg2+ binding sites in ion-dependent gating of a Mg2+ channel, MgtE, revealed by solution NMR2018

    • Author(s)
      Maruyama Tatsuro、Imai Shunsuke、Kusakizako Tsukasa、Hattori Motoyuki、Ishitani Ryuichiro、Nureki Osamu、Ito Koichi、Maturana Andr?s D、Shimada Ichio、Osawa Masanori
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.31596

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-18H04679, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
  • [Journal Article] 特集 いかに創薬を進めるか NMRで標的タンパク質の機能から創薬を2018

    • Author(s)
      上田 卓見、嶋田 一夫
    • Journal Title

      生体の科学

      Volume: 69 Issue: 4 Pages: 315-319

    • DOI

      10.11477/mf.2425200823

    • ISSN
      0370-9531, 1883-5503
    • Year and Date
      2018-08-15
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Journal Article] Dynamic domain arrangement of CheA-CheY complex regulates bacterial thermotaxis, as revealed by NMR2017

    • Author(s)
      YuYuichi Minato, Takumi Ueda, Asako Machiyama, Hideo Iwai, Ichio Shimada
    • Journal Title

      as revealed by NMR Scientific Reports

      Volume: 7 Issue: 1 Pages: 16462-16462

    • DOI

      10.1038/s41598-017-16755-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01531
  • [Journal Article] ATP-dependent modulation of MgtE in Mg2+ homeostasis2017

    • Author(s)
      Tomita Atsuhiro、Zhang Mingfeng、Jin Fei、Zhuang Wenhui、Takeda Hironori、Maruyama Tatsuro、Osawa Masanori、Hashimoto Ken-ichi、Kawasaki Hisashi、Ito Koichi、Dohmae Naoshi、Ishitani Ryuichiro、Shimada Ichio、Yan Zhiqiang、Hattori Motoyuki、Nureki Osamu
    • Journal Title

      Nature Communications

      Volume: 8 Issue: 1 Pages: 148-148

    • DOI

      10.1038/s41467-017-00082-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16H06294
  • [Journal Article] Forbidden Coherence Transfer of 19F Nuclei to Quantitatively Measure the Dynamics of a CF3-Containing Ligand in Receptor-Bound States2017

    • Author(s)
      Tokunaga Yuji、Takeuchi Koh、Shimada Ichio
    • Journal Title

      Molecules

      Volume: 22 Issue: 9 Pages: 1492-1492

    • DOI

      10.3390/molecules22091492

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K15083, KAKENHI-PROJECT-17H06097
  • [Journal Article] A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis2017

    • Author(s)
      S. Ito, K. Ogawa, K. Takeuchi, M. Takagi, M. Yoshida, T. Hirokawa, S. Hirayama, K. Shin-Ya, I. Shimada, T. Doi, N. Goshima, T. Natsume, K. Nagata
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Issue: 49 Pages: 20076-20085

    • DOI

      10.1074/jbc.m117.815936

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24227009, KAKENHI-PROJECT-17H06097, KAKENHI-PROJECT-16K20998
  • [Journal Article] Nuclear Magnetic Resonance Approaches for Characterizing Protein-Protein Interactions2017

    • Author(s)
      Toyama Yuki、Mase Yoko、Kano Hanaho、Yokogawa Mariko、Osawa Masanori、Shimada Ichio
    • Journal Title

      Methods in Molecular Biology (invited review)

      Volume: 1684 Pages: 115-128

    • DOI

      10.1007/978-1-4939-7362-0_10

    • ISBN
      9781493973613, 9781493973620
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H06097, KAKENHI-PUBLICLY-16H01368, KAKENHI-PROJECT-17H03978, KAKENHI-PROJECT-16K18866, KAKENHI-PROJECT-18K06606
  • [Journal Article] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2016

    • Author(s)
      Minato Y, Suzuki S , Hara T, Kofuku Y, Kasuya G, Fujiwara Y, Igarashi S, Suzuki E, Nureki O, Hattori M, Ueda T, Shimada I
    • Journal Title

      Proc. Natl. Acad. Sci.

      Volume: 発行中 Issue: 17 Pages: 4741-4746

    • DOI

      10.1073/pnas.1600519113

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-25670108, KAKENHI-PUBLICLY-26120506, KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-16K08191, KAKENHI-PROJECT-16K15180, KAKENHI-PUBLICLY-16H01353
  • [Journal Article] Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data2015

    • Author(s)
      Ueda T, Yoshiura C, Matsumoto M, Kofuku Y, Okude J, Kondo K, Shiraishi Y, Takeuchi K, Shimada I
    • Journal Title

      J. Biomol. NMR

      Volume: 印刷中 Issue: 1 Pages: 31-41

    • DOI

      10.1007/s10858-015-9908-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-26893041, KAKENHI-PROJECT-15K18843, KAKENHI-PUBLICLY-26120506, KAKENHI-PROJECT-15J12409
  • [Journal Article] Elucidation of the CCR1- and CCR5-binding modes of MIP-1α by application of an NMR spectra reconstruction method to the transferred cross-saturation experiments.2015

    • Author(s)
      Chie Yoshiura, Takumi Ueda, Yutaka Kofuku, Masahiko Matsumoto, Junya Okude, Keita Kondo, Yutaro Shiraishi, Ichio Shimada
    • Journal Title

      Journal of Biomolecular NMR

      Volume: 63 Issue: 4 Pages: 333-340

    • DOI

      10.1007/s10858-015-9992-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-15J12409, KAKENHI-PROJECT-25460033, KAKENHI-PUBLICLY-26120506
  • [Journal Article] Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor.2015

    • Author(s)
      Junya Okude, Takumi Ueda, Yutaka Kofuku, Motohiko Sato, Naoyuki Nobuyama, Keita Kondo, Yutaro Shiraishi, Takuya Mizumura, Kento Onishi, Mei Natsume, Masahiro Maeda, Hideki Tsujishita, Takefumi Kuranaga, Masayuki Inoue, Ichio Shimada
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 21 Issue: 52 Pages: 15771-15776

    • DOI

      10.1002/anie.201508794

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K18843, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-15J12409, KAKENHI-PROJECT-25460033, KAKENHI-PUBLICLY-26120506
  • [Journal Article] Suppression of problematic compound oligomerization by cosolubilization of nondetergent sulfobetaines2015

    • Author(s)
      Mizukoshi Y, Takeuchi K, Arutaki M, Takizawa T, Hanzawa H, Takahashi H, Shimada I
    • Journal Title

      ChemMedChem

      Volume: 10 Issue: 4 Pages: 736-741

    • DOI

      10.1002/cmdc.201500057

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Dynamic multidrug recognition by multidrug transcriptional repressor LmrR2014

    • Author(s)
      Takeuchi K, Tokunaga Y, Imai M, Takahashi H, Shimada I.
    • Journal Title

      Sci Rep

      Volume: 4 Issue: 1 Pages: 6922-6922

    • DOI

      10.1038/srep06922

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-26102735
  • [Journal Article] Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT2014

    • Author(s)
      Esaki K, Yoshinaga S, Tsuji T, Toda E, Terashima Y, Saitoh T, Kohda D, Kohno T, Osawa M, Ueda T, Shimada I, Matsushima K, Terasawa H
    • Journal Title

      FEBS J

      Volume: 281 Issue: 24 Pages: 552-566

    • DOI

      10.1111/febs.13096

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707, KAKENHI-PROJECT-26670326, KAKENHI-PROJECT-26860317
  • [Journal Article] Functional dynamics of cell surface membrane proteins2014

    • Author(s)
      Nishida N, Osawa M, Takeuchi K, Imai S, Stampoulis P, Kofuku Y, Ueda T, Shimada I
    • Journal Title

      J Magn Reson

      Volume: 241 Pages: 86-96

    • DOI

      10.1016/j.jmr.2013.11.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PUBLICLY-25121743, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
  • [Journal Article] Development of a method for reconstruction of crowded NMR spectra from undersampled time-domain data2014

    • Author(s)
      Ueda T, Yoshiura C, Matsumoto M, Kofuku Y, Okude J, Kondo K, Shiraishi Y, Takeuchi K, Shimada I.
    • Journal Title

      J Biomol NMR

      Volume: なし

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments2014

    • Author(s)
      Ueda T, Takeuchi K, Nishida N, Stampoulis P, Kofuku Y, Osawa M, Shimada I
    • Journal Title

      Q Rev Biophys

      Volume: 47 Issue: 2 Pages: 143-187

    • DOI

      10.1017/s0033583514000043

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-25121707, KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PLANNED-26119005
  • [Journal Article] Backbone resonance assignments for G protein αi3 subunit in the GDP-bound state.2014

    • Author(s)
      Mase Y., Yokogawa M., Osawa M., and Shimada I.
    • Journal Title

      Biomol. NMR Assign.

      Volume: 8 Issue: 2 Pages: 237-241

    • DOI

      10.1007/s12104-013-9491-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
  • [Journal Article] Structure-based approach to improve a small-molecule inhibitor by the use of a competitive peptide ligand.2014

    • Author(s)
      Ono K, Takeuchi K, Ueda H, Morita Y, Tanimura R, Shimada I, Takahashi H.
    • Journal Title

      Angew Chem Int Ed Engl

      Volume: 53 Issue: 10 Pages: 2597-2597

    • DOI

      10.1002/anie.201310749

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-25121743
  • [Journal Article] Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy2014

    • Author(s)
      Kofuku Y, Ueda T, Okude J, Shiraishi Y, Kondo K, Mizumura T, Suzuki S, Shimada I
    • Journal Title

      Angew Chem Int Ed Engl

      Volume: 53 Issue: 49 Pages: 13376-13379

    • DOI

      10.1002/anie.201406603

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PUBLICLY-25121708, KAKENHI-PROJECT-25460033, KAKENHI-PROJECT-26893041, KAKENHI-PUBLICLY-26120506
  • [Journal Article] Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions2014

    • Author(s)
      Tokunaga Y, Takeuchi K, Takahashi H, Shimada I
    • Journal Title

      Nat Struct Mol Biol

      Volume: 21 Issue: 8 Pages: 704-711

    • DOI

      10.1038/nsmb.2861

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-25121743, KAKENHI-PUBLICLY-26102735
  • [Journal Article] Identification of a binding element for the cytoplasmic regulator FROUNTin the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.2014

    • Author(s)
      Toda E, Terashlma Y, Esakii K, Yoshinaga S, Sugihara M, Kofuku Y, Shimada I, Suwa M, Kanegasaki S, Terasawa H, Matsushima K.
    • Journal Title

      Biochemical Journal

      Volume: Vol.457 Issue: 2 Pages: 313-322

    • DOI

      10.1042/bj20130827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J40099, KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24790462, KAKENHI-PROJECT-26670326, KAKENHI-PROJECT-26860317
  • [Journal Article] Backbone resonance assignments for G protein α(i3) subunit in the GDP-bound state2013

    • Author(s)
      Mase Y, Yokogawa M, Osawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Backbone resonance assignments for the cytoplasmic region of the Mg(2+) transporter MgtE in the Mg (2+)-unbound state2013

    • Author(s)
      Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
    • Journal Title

      Biomol NMR Assign

      Volume: 7 Issue: 1 Pages: 93-96

    • DOI

      10.1007/s12104-012-9385-y

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040, KAKENHI-PROJECT-22687007, KAKENHI-PUBLICLY-23107708, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707
  • [Journal Article] Backbone resonance assignments for G protein α(i3) subunit in the GDP-bound state2013

    • Author(s)
      Mase Y, Yokogawa M, Osawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Backbone and side-chain (1)H, (15)N and (13)C resonance assignments of the microtubule-binding domain of yeast cytoplasmic dynein in the high and low-affinity states2013

    • Author(s)
      Takarada O, Nishida N, Kikkawa M, Shimada I
    • Journal Title

      Biomol NMR Assign

      Volume: (印刷中)

    • Data Source
      KAKENHI-PROJECT-24770090
  • [Journal Article] Rapid identification of ligand-binding sites by using an assignment-free NMR approach2013

    • Author(s)
      Kodama Y, Takeuchi K, Shimba N, Ishikawa K, Suzuki E, Shimada I, Takahashi H.
    • Journal Title

      J Med Chem

      Volume: 56 Issue: 22 Pages: 9342-9350

    • DOI

      10.1021/jm4014357

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24102524, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-25121743
  • [Journal Article] A Gel-Encapsulated Bioreactor System for NMR Studies of Protein-Protein Interactions in Living Mammalian Cells2013

    • Author(s)
      Satoshi Kubo, Noritaka Nishida, Yuko Udagawa, Osamu Takarada, Shinji Ogino, Ichio Shimada
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 52 Issue: 4 Pages: 1208-1211

    • DOI

      10.1002/anie.201207243

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J11066, KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24770090
  • [Journal Article] Nuclear magnetic resonance approaches for characterizing interactions between the bacterial chaperonin GroEL and unstructured proteins.2013

    • Author(s)
      Nishida N, Yagi-Utsumi M, Motojima F, Yoshida M, Shimada I, Kato K.
    • Journal Title

      J Biosci Bioeng

      Volume: 116 Issue: 2 Pages: 160-164

    • DOI

      10.1016/j.jbiosc.2013.02.012

    • NAID

      110009657195

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23870043, KAKENHI-PROJECT-24770090, KAKENHI-PLANNED-20107004
  • [Journal Article] Backbone and side-chain 1H, 15N and 13C resonance assignments of the microtubule-binding domain of yeast cytoplasmic dynein in the high and low-affinity states2013

    • Author(s)
      Takarada O, Nishida N, Kikkawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Journal Article] Structure of the Mouse Sex Peptide Pheromone ESP1 Reveals a Molecular Basis for Specific Binding to the Class C G-protein-coupled Vomeronasal Receptor2013

    • Author(s)
      Yoshinaga S, Sato T, Hirakane M, Esaki K, Hamaguchi T, Haga-Yamanaka S, Tsunoda M, Kimoto H, Shimada I, Touhara K, Terasawa H
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 288 Issue: 22 Pages: 16064-72

    • DOI

      10.1074/jbc.m112.436782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02683, KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24780104
  • [Journal Article] Solution NMR study on functional mechanism of membrane proteins2013

    • Author(s)
      Osawa M., Imai S., Takeuchi K, and Shimada I.
    • Journal Title

      Seibutsubutsuri

      Volume: 53 Pages: 236-241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Journal Article] Perdeuteration and methyl-selective (1)H, (13)C-labeling by using a Kluyveromyces lactis expression system2013

    • Author(s)
      Miyazawa-Onami M, Takeuchi K, Takano T, Sugiki T, Shimada I, Takahashi H.
    • Journal Title

      J Biomol NMR

      Volume: 57 Issue: 3 Pages: 297-304

    • DOI

      10.1007/s10858-013-9789-8

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24102524, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-25121743
  • [Journal Article] Backbone and side-chain (1)H, (15)N and (13)C resonance assignments of the microtubule-binding domain of yeast cytoplasmic dynein in the high and low-affinity states.2013

    • Author(s)
      Takarada O, Nishida N, Kikkawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] An NMR method to study prolein-protcin interaction2012

    • Author(s)
      Noritaka Nishida, Ichio Shimadn
    • Journal Title

      Methods Mol. Biol.

      Volume: 757 Pages: 129-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Backbone resonance assignments for the cytoplasmic region of the Mg^<2+> transporter MgtE in the Mg^<2+-> unboundstate2012

    • Author(s)
      Maruyama T, Imai S, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
    • Journal Title

      Biomol NMR Assign

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)2012

    • Author(s)
      Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, Shimada I.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 33706-33718

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Spatial distribution of cytoplasmic domains of the Mg(2+)-transporter MgtE, in a solution lacking Mg(2+), revealed by paramagnetic relaxation enhancement2012

    • Author(s)
      Imai S, Maruyama T, Osawa M, Hattori M, Ishitani R, Nureki O, Shimada I.
    • Journal Title

      Biochim Biophys Acta

      Volume: 1824 Issue: 10 Pages: 1129-1135

    • DOI

      10.1016/j.bbapap.2012.06.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-22687007, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Isotopic labeling of heterologous proteins in the yeast Pichia pastoris and Kluyveromyces lactis2012

    • Author(s)
      Sugiki T, Ichikawa O, Miyazawa-Onami M, Shimada I, Takahashi H.
    • Journal Title

      Methods Mol Biol

      Volume: 831 Pages: 19-36

    • DOI

      10.1007/978-1-61779-480-3_2

    • ISBN
      9781617794797, 9781617794803
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK)by the i/o-family G protein α subunit (Gdi_<i/o>)2012

    • Author(s)
      間瀬瑶子
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 287 Issue: 23 Pages: 19537-19549

    • DOI

      10.1074/jbc.m112.353888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J08566, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Efficacy of the β2-adrenergic receptor is determined by conformational equilibrium in the transmembrane region2012

    • Author(s)
      Kofuku Y, Ueda T, Okude J, Shiraishi Y, Kondo K, Maeda M, Tsujishita H, Shimada I
    • Journal Title

      Nat Commun.

      Volume: 3 Issue: 1 Pages: 1045-1045

    • DOI

      10.1038/ncomms2046

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PUBLICLY-23121511, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Isotopic labeling of heterologous proteins in the yeast Pichia pastoris and Kluyveromyces lactis2012

    • Author(s)
      Toshihiko Sugiki, Osamu Ichikawa, Mayumi Miyazawa, -Onami, Ichio Shimada, Hideo Takahashi
    • Journal Title

      Methods Mol.Biol.(2012)831,19-36

      Volume: 831 Pages: 19-36

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Backbone resonance assignments for Gproteinτ(i3) subunit in the GTP-boundstate2012

    • Author(s)
      Mase Y, Yokogawa M, Osawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)2012

    • Author(s)
      Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, Shimada I.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 33706-33718

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] An NMR method to study protein-protein interaction2012

    • Author(s)
      Noritaka Nishida, Ichio Shimada
    • Journal Title

      Methods Mol.Biol.

      Volume: 757 Pages: 129-37

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] NMR study of ligand release from asialoglycoprotein receptor under solution conditions in early endosomes2012

    • Author(s)
      Onizuka T, Shimizu H, Moriwaki Y, Nakano T, Kanai S, Shimada I, Takahashi H.
    • Journal Title

      FEBS J

      Volume: 279 Issue: 15 Pages: 2645-2656

    • DOI

      10.1111/j.1742-4658.2012.08643.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23570146, KAKENHI-PROJECT-24370048, KAKENHI-PUBLICLY-24102524, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Functional equilibrium of the KcsA structure revealed by NMR2012

    • Author(s)
      Imai S, Osawa M, Mita K, Toyonaga S, Machiyama A, Ueda T, Takeuchi K, Oiki S, Shimada I.
    • Journal Title

      J Biol Chem

      Volume: 287 Issue: 47 Pages: 39634-39641

    • DOI

      10.1074/jbc.m112.401265

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23370067, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24659096, KAKENHI-PROJECT-24659097, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Backbone resonance assignments for G protein α(i3) subunit in the GTP-bound state2012

    • Author(s)
      Mase Y, Yokogawa M, Osawa M, Shimada I.
    • Journal Title

      Biomol NMR Assign

      Volume: 6 Issue: 2 Pages: 217-220

    • DOI

      10.1007/s12104-012-9361-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040, KAKENHI-PUBLICLY-23107708, KAKENHI-PROJECT-24590048, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Functional dynamics of proteins revealed by solution NMR2012

    • Author(s)
      Osawa M, Takeuchi K, Ueda T, Nishida N, Shimada I.
    • Journal Title

      Curr Opin Struct Biol

      Volume: 22 Issue: 5 Pages: 660-669

    • DOI

      10.1016/j.sbi.2012.08.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24770090, KAKENHI-PUBLICLY-23107708, KAKENHI-PUBLICLY-23107735, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structural Basis of Efficient Electron Transport between Photosyn thetic Membrane Proteins and Plastocyanin in Spinach Revealed using Nuclear Magnetic Resonance2012

    • Author(s)
      Takumi Ueda, Naoko Nomoto, Masamichi Koga, Hiroki Ogasa, Yuuta Ogawa, Masahiko Matsumoto, Pavlos Stampoulis, Koji Sode, Hiroaki Terasawa and Ichio Shimada
    • Journal Title

      Plant Cell

      Volume: 24 Issue: 10 Pages: 4173-4186

    • DOI

      10.1105/tpc.112.102517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J00159, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23790042, KAKENHI-PUBLICLY-23121511, KAKENHI-ORGANIZER-21121001
  • [Journal Article] An NMR method to study protein-protein interactions2012

    • Author(s)
      Nishida N, Shimada I.
    • Journal Title

      Methods Mol Biol

      Volume: 757 Pages: 129-137

    • DOI

      10.1007/978-1-61779-166-6_10

    • ISBN
      9781617791659, 9781617791666
    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24770090, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Biological role of the two overlapping poly(A)-binding protein interacting motifs 2 (PAM2) of eukaryotic releasing factor eRF3 in mRNA decay.2012

    • Author(s)
      Osawa M, Hosoda N, Nakanishi T, Uchida N, Kimura T, Imai S, Machiyama A, Katada T, Hoshino S, Shimada I.
    • Journal Title

      RNA

      Volume: 18 Issue: 11 Pages: 1957-1967

    • DOI

      10.1261/rna.035311.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-23659045, KAKENHI-PUBLICLY-24113513, KAKENHI-PROJECT-24570050, KAKENHI-PROJECT-24590048, KAKENHI-PROJECT-24657081, KAKENHI-PLANNED-20112005, KAKENHI-PUBLICLY-23107708, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Segmental isotopic labeling of a 140 kDa dimeric multi-domain protein CheA from Escherichia coli by expressed protein ligation and protein trans-splicing2012

    • Author(s)
      Minato Y, Ueda T, Machiyama A, Shimada l, Iwai H
    • Journal Title

      Journal of Biomolecular NMR

      Volume: 53 Issue: 3 Pages: 191-207

    • DOI

      10.1007/s10858-012-9628-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J11124, KAKENHI-PLANNED-21121002, KAKENHI-ORGANIZER-21121001
  • [Journal Article] Isolopic labeling of heterologous proteins in the yeast Pichia pastoris and Kluyvcromyccs lactis2012

    • Author(s)
      Toshihiko Sugiki, Osamu Ichikawa, Mayumi Miyazawa,-Onami, Ichio Shimada, Hideo Takaliashi
    • Journal Title

      Methods Mol. Biol. (2012) 831, 19-36.,

      Volume: 831 Pages: 19-36

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] NMR Analyses of the GβγBinding and Conformational Rearrangements of the Cytoplasmic Pore of G Protein-activated Inwardly Rectifying Potassium Channel 1(GIRK1)2011

    • Author(s)
      Yokogawa M, Osawa M, Takeuchi K, MaseY, Shimada I.
    • Journal Title

      J. Biol. Chem

      Volume: 286 Issue: 3 Pages: 2215-2223

    • DOI

      10.1074/jbc.m110.160754

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling : a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment2011

    • Author(s)
      Koh Takeuchi, Maayan Gal, Hideo Takahashi, Ichio Shimada, Gerhard Wagner
    • Journal Title

      J.Biomol.NMR

      Volume: 49 Pages: 17-26

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structure determination of a protein assembly by amino acid selective cross-saturation2011

    • Author(s)
      Eiji Kanamori, Shunsuke Igarashi, Masanori Osawa, Yoshifumi Fukunishi, Ichio Shimada, Haruki Nakamura
    • Journal Title

      Proteins

      Volume: 79 Pages: 179-190

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] CD44の準安定なヒアルロン酸認識機構と細胞ローリング2011

    • Author(s)
      西田紀貴,嶋田一夫
    • Journal Title

      生化学

      Volume: 83(10) Pages: 893-901

    • NAID

      10029850105

    • URL

      http://www.jbsoc.or.jp/seika/wp-content/uploads/2013/05/83-10-02.pdf

    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Affinity transfer to human protein by CDR3 grafting of camelid VHH2011

    • Author(s)
      Hidetoshi Inoue, Akiko IIhara, Hideo Takahashi, Ichio Shimada, Isao Ishida, Yoshitake Maeda
    • Journal Title

      Protein Sci.

      Volume: 20 Pages: 1971-81

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structure determination of a protein assembly by amino acid selective cross-saturation2011

    • Author(s)
      Eiji Kanamori, Shunsuke Igarashi, Masanori Osawa, Yoshifumi Fukunishi, Ichio Shimada, Haruki Nakamura
    • Journal Title

      Proteins

      Volume: 79 Pages: 179-190

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structure determination of a protein assembly by amino acid selective cross-saturation2011

    • Author(s)
      Kanamori E., Igarashi S., Osawa M., Fukunishi Y., Shimada I., Nakamura H.
    • Journal Title

      Proteins

      Volume: 79 Issue: 1 Pages: 179-190

    • DOI

      10.1002/prot.22871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Protein-ligand docking guided by ligand pharmacophore-mapping experiment by NMR2011

    • Author(s)
      Yoshifumi Fukunishi, Yumiko Mizukoshi, Koh Takeuchi, Ichio Shimada, Hideo Takahashi, Haruki Nakamura
    • Journal Title

      J. Mol. Graph. Model.

      Volume: 31 Pages: 20-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] An Accurate Pharmacophore Mapping Method by NMR2011

    • Author(s)
      Yumiko Mizukoshi, Aya Abe, Takeshi Takizawa, Hiroyuki Hanzawa, Yoshifumi Fukunishi, Ichio Shimada, Hideo Takahashi
    • Journal Title

      Angew.Chem.In Ed Engl.(2011)

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Affinity transfer to human protein by CDR3 grafting of camelid VHH2011

    • Author(s)
      Hidetoshi Inoue, Akiko Ilhara, Hideo Takahashi, Ichio Shimada, Isao Ishidal, Yoshitake Maeda
    • Journal Title

      Protein Sci.

      Volume: 20 Pages: 1971-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] HNCA-TOCSY-CANH experiments with alternate 13C-12C labeling : a set of 3D experiment with unique supra-sequential information for mainchain resonance assignment2011

    • Author(s)
      Koh Takeuchi, Maayan Gal, Hideo Takahashi, Ichio Shimada, Gerhard Wagner
    • Journal Title

      J.Biomol.NMR

      Volume: 49 Pages: 17-26

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Protein-ligand docking guided by ligand pharmacophore-mapping experiment by NMR2011

    • Author(s)
      Yoshifumi Fukunishi, Yumiko Mizukoshi, Koh Takeuchi, Ichio Shimada, Hideo Takahashi, Haruki Nakamura
    • Journal Title

      J.Mol.Graph.Model.

      Volume: 31 Pages: 20-7

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Rapid Identification of Protein-Protein Interfaces and Construction of Complex Model Based on Multiple Unassigned Signals By Using Time-sharing NMR Measurement2011

    • Author(s)
      Yuya Kodama, Michael L.Reese, Nobuhisa Shimba, Volker Dotsch, Ei-ichiro Suzuki, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J.Struct.Biol.

      Volume: 174 Pages: 434-42

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] An Accurate Pharmacophore Mapping Method by NMR2011

    • Author(s)
      Yumiko Mizukoshi, Aya Abe, Takeshi Takizawa, Hiroyuki Hanzawa, Yoshifumi Fukunishi, Ichio Shimada, Hideo Taknhashi
    • Journal Title

      Angew. Chem. In Ed Engl. (2011)

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Rapid Identification of Protein-Protein Interfaces and Construction of Complex Model Based on Multiple Unassigned Signals By Using Time-sharing NMR Measurement2011

    • Author(s)
      Yuya Kodama, Michael L, Reese, Nobuhisa Shimba, Volker Dotsch, Ei-ichiro Suzuki, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J. Struct. Biol.

      Volume: 174 Pages: 434-42

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Quantitative characterization of the Tob interactions provides the thermodynamic basis on the translation termination-coupled deadenylase regulation2010

    • Author(s)
      Lin Ruan, Masanori Osawa, Nao Hosoda, Shunsuke Imai, Asako Machiyama, Toshiaki Katada, Shin-ichi Hoshino, Ichio Shimada
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 27624-27631

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010

    • Author(s)
      Yoshiura C, Kofuku Y, Ueda T, Mase Y, Yokogawa M, Osawa M, Terashima Y, Matsushima K, Shimada I
    • Journal Title

      J Am Chem Soc.

      Volume: 132(19) Issue: 19 Pages: 6768-77

    • DOI

      10.1021/ja100830f

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040
  • [Journal Article] Real-time assay method of lipid extraction activity2010

    • Author(s)
      Toshihiko Sugiki, Hideo Takahashi, Michiko Nagasu, Kentaro Hanada, Ichio Shimada
    • Journal Title

      Anal.Biochem.

      Volume: 399 Pages: 162-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Theoretical analyses of the transferred cross-saturation method, Epub 20102010

    • Author(s)
      Matsumoto M, Ueda T, Shimada I
    • Journal Title

      J Magn Reson.

      Volume: 205(1) Issue: 1 Pages: 114-24

    • DOI

      10.1016/j.jmr.2010.04.011

    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Production of isotopically labeled heterologous proteins in non-E.coli prokaryotic and eukaryotic cells2010

    • Author(s)
      Hideo Takahashi, Ichio Shimada
    • Journal Title

      J.Biomol.NMR

      Volume: 46 Pages: 3-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Quantitative characterization of the Tob interactions provides the thermodynamic basis on the translation termination-coupled deadenylase regulation2010

    • Author(s)
      Lin Ruan, Masanori Osawa, Nao Hosoda, Shunsuke Imai, Asako Machiyama, Toshiaki Katada, Shin-ichi Hoshino, Ichio Shimada
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 27624-27631

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Two-state conformations in the hyaluronan-binding domain regulate CD44 adhesiveness under flow condition2010

    • Author(s)
      Ogino S, Nishida N, Umemoto R, Suzuki M, Takeda M, Terasawa H, Kitayama J, Matsumoto M, Hayasaka H, Miyasaka M, Shimada I
    • Journal Title

      Structure.

      Volume: 18(5) Issue: 5 Pages: 649-56

    • DOI

      10.1016/j.str.2010.02.010

    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010

    • Author(s)
      Chie Yoshiura, Yutaka Kofuku, Takumi Ueda, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Yuya Terashima, Kouji Matsushima, Ichio Shimada
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 6768-6777

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments2010

    • Author(s)
      Takefumi Nakamura, Hideo Takahashi, Mitsuo Takahashi, Nobuhisa Shimba, Ei-ichiro Suzuki, Ichio Shimada
    • Journal Title

      J.Med.Chem.

      Volume: 53 Pages: 2087-2093

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Direct determination of the insulin-insulin receptor interface using transferred cross-saturation experiments2010

    • Author(s)
      Takefumi Nakamura, Hideo Takahashi, Mitsuo Takahashi, Nobuhisa Shimba, Ei-ichiro Suzuki, Ichio Shimada
    • Journal Title

      J.Med.Chem.

      Volume: 53 Pages: 2087-2093

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Two-state conformational equilibrium of the hyaluronan-binding domain regulates adhesiveness of CD44 under flow condition2010

    • Author(s)
      Shinji Ogino, Noritaka Nishida, Ryo Umemoto, Miho Suzuki, Mitsuhiro Takeda, Hiroaki Terasawa, Joji Kitayama, Masanori Matsumoto, Haruko Hayasaka, Masayuki Miyasaka, Ichio Shimada
    • Journal Title

      Structure

      Volume: 18 Pages: 649-656

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] NMR analyses of the interaction between CCR5 and its ligand using functional reconstitution of CCR5 in lipid bilayers2010

    • Author(s)
      Chie Yoshiura, Yutaka Kofuku, Takumi Ueda, Yoko Mase, Mariko Yokogawa, Masanori Osawa, Yuya Terashima, Kouji Matsushima, Ichio Shimada
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 132 Pages: 6768-6777

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Backbone resonance assignments for the ligand binding subunit of the histidine permease complex (HisJ) from Escherichia coli, under histidine-bound and unbound states.2010

    • Author(s)
      Igarashi S, Osawa M, Ozawa S, Shimada I.
    • Journal Title

      Biomol NMR Assign.

      Volume: 4 Pages: 7-20

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Two-state conformational equilibrium of the hyaluronan-binding domain regulates adhesiveness of CD44 under flow condition2010

    • Author(s)
      Shinji Ogino, Noritaka Nishida, Ryo Umemoto, Miho Suzuki, Mitsuhiro Takeda, Hiroaki Terasawa, Joji Kitayama, Masanori Matsumoto, Haruko Hayasaka, Masayuki Miyasaka, Ichio Shimada
    • Journal Title

      Structure

      Volume: 18 Pages: 649-656

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Real-time assay method of lipid extraction activity2010

    • Author(s)
      Toshihiko Sugiki, Hideo Takahashi, Michiko Nagasu, Kentaro Hanada, Ichio Shimada
    • Journal Title

      Anal.Biochem.

      Volume: 399 Pages: 162-167

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Theoretical analyses of the transferred cross-saturation method2010

    • Author(s)
      Masahiko Matsumoto, Takumi Ueda, Ichio Shimada
    • Journal Title

      J.Magn.Reson.

      Volume: 205 Pages: 114-124

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Structural Basis for Platelet Anti-aggregation by AT1-Receptor Antagonist Losartan via Glycoprotein VI2010

    • Author(s)
      Katsuki Ono, Hiroshi Ueda, Yoshitaka Yoshizawa, Daisuke Akazawa, Ryuji Tanimura, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J.Med.Chem.

      Volume: 53 Pages: 1917-1922

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation2010

    • Author(s)
      Ruan L., Osawa M., Hosoda N., Imai S., Machiyama A., Katada T., Hoshino S., Shimada I.
    • Journal Title

      J. Biol. Chem

      Volume: 285(36) Issue: 36 Pages: 27624-27631

    • DOI

      10.1074/jbc.m110.138867

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Production of isotopically labeled heterologous proteins in non-E.coli prokaryotic and eukaryotic cells2010

    • Author(s)
      Hideo Takahashi, Ichio Shimada
    • Journal Title

      J.Biomol.NMR

      Volume: 46 Pages: 3-10

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] NMR structure of the calponin homology domain of human IQGAP1 and its implications for the actin recognition mode2010

    • Author(s)
      Ryo Umemotoa, Noritaka Nishida, Shinji Oginoa, Ichio Shimada
    • Journal Title

      J.Biomol.NMR

      Volume: 48 Pages: 59-64

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Precise structural determination of weakly binding peptides by utilizing dihedral angle constraints2010

    • Author(s)
      Yumiko Mizukoshi, Michiko Nagasu, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J.Biomol.NMR

      Volume: 46 Pages: 299-305

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structural basis underlying the dual gate properties of KcsA2010

    • Author(s)
      Imai S, Osawa M, Takeuchi K, Shimada I
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 107(14) Issue: 14 Pages: 6216-21

    • DOI

      10.1073/pnas.0911270107

    • Data Source
      KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-21590040
  • [Journal Article] Backbone resonance assignments for the ligand binding subunit of the histidine permeasecomplex(HisJ) from Escherichia coli, under histidine-bound and unbound states2010

    • Author(s)
      Igarashi S., Osawa M., Ozawa S., Shimada I.
    • Journal Title

      Biomol. NMR Assign

      Volume: 4(1) Issue: 1 Pages: 17-20

    • DOI

      10.1007/s12104-009-9200-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Backbone resonance assignments for the ligand binding subunit of the histidine permease complex (HisJ) from Escherichia coli, under histidine-bound and unbound states.2010

    • Author(s)
      Igarashi S, Osawa M, Ozawa S, Shimada I.
    • Journal Title

      Biomol NMR Assign.

      Volume: 4 Pages: 7-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] NMR structure of the calponin homology domain of human IQGAP1 and its implications for the actin recognition mode2010

    • Author(s)
      Ryo Umemotoa, Noritaka Nishida, Shinji Oginoa, Ichio Shimada
    • Journal Title

      J.Biomol.NMR

      Volume: 48 Pages: 59-64

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Theoretical analyses of the transferred cross-saturation method2010

    • Author(s)
      Masahiko Matsumoto, Takumi Ueda, Ichio Shimada
    • Journal Title

      J.Magn.Reson.

      Volume: 205 Pages: 114-124

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structural basis underlying the dual gate properties of KcsA2010

    • Author(s)
      Shunsuke Imai, Masanori Osawa, Koh Takeuchi, Ichio Shimada
    • Journal Title

      Proc.Natl.Acad.Sci.USA.

      Volume: 107 Pages: 6216-6221

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Precise structural determination of weakly binding peptides by utilizing dihedral angle constraints2010

    • Author(s)
      Yumiko Mizukoshi, Michiko Nagasu, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J.Biomol.NMR

      Volume: 46 Pages: 299-305

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Structural basis underlying the dual gate properties of KcsA2010

    • Author(s)
      Shunsuke Imai, Masanori Osawa, Koh Takeuchi, Ichio Shimada
    • Journal Title

      Proc.Natl.Acad.Sci.USA.

      Volume: 107 Pages: 6216-6221

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Structural Basis for Platelet Anti-aggregation by AT1-Receptor Antagonist Losartan via Glycoprotein VI2010

    • Author(s)
      Katsuki Ono, Hiroshi Ueda, Yoshitaka Yoshizawa, Daisuke Akazawa, Ryuji Tanimura, Ichio Shimada, Hideo Takahashi
    • Journal Title

      J.Med.Chem.

      Volume: 53 Pages: 1917-1922

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments.2009

    • Author(s)
      Shimada I
    • Journal Title

      Prog.Nuc.Magn.Reson.Spect. 54

      Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Evidence for the direct interaction of spermine with the inwardly rectifying potassium channel2009

    • Author(s)
      Osawa M., Yokogawa M., Muramatsu T., Kimura T., Mase Y., Shimada I.
    • Journal Title

      J. Biol. Chem

      Volume: 284(38) Issue: 38 Pages: 26117-26126

    • DOI

      10.1074/jbc.m109.029355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments2009

    • Author(s)
      Shimada I
    • Journal Title

      Prog.Nuc.Magn.Reson.Spect. 54

      Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20051005
  • [Journal Article] Observation of NMR signals from proteins introduced into living mammalian cells by reversible membrane permeabilization using a pore-forming toxin2009

    • Author(s)
      S. Ogino, S. Kubo, R. Umemoto, S. Huang, N. Nishida, I. Shimada
    • Journal Title

      Streptolysin O.J. Am. Chem. Soc. 131

      Pages: 10834-10835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083101
  • [Journal Article] Observation of NMR signals from proteins introduced into living mammalian cells by reversible membrane permeabilization using a pore-forming toxin, Streptolysin O2009

    • Author(s)
      Ogino S, Kubo S, Umemoto R, Huang S, Nishida N, Shimada I
    • Journal Title

      J Am Chem Soc.

      Volume: 131(31) Issue: 31 Pages: 10834-5

    • DOI

      10.1021/ja904407w

    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Structural Basis of the Interaction between Chemokine Stromal Cell-derived Factor-1/CXCL12 and Its G-protein-coupled Receptor CXCR42009

    • Author(s)
      Kofuku Y, Yoshiura C, Ueda T, Terasawa H, Hirai T, Tominaga S, Hirose M, Maeda Y, Takahashi H, Terashima Y, Matsushima K, Shimada I
    • Journal Title

      J Biol Chem.

      Volume: 284(50) Issue: 50 Pages: 35240-50

    • DOI

      10.1074/jbc.m109.024851

    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments2009

    • Author(s)
      Ichio Shimada, Takumi Ueda, Masahiko Matsumoto, Masayoshi Sakakura, Masanori Osawa, Koh Takeuchi, Noritaka Nishida, Hideo Takahashi
    • Journal Title

      Prog. Nuc. Magn. Reson. Spect. 54

      Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments2009

    • Author(s)
      Shimada I., Ueda T., Matsumoto M., Sakakura M., Osawa M., Takeuchi K., Nishida N., Takahashi H.
    • Journal Title

      Prog. Nuc. Magn. Reson. Spect

      Volume: 54 Issue: 2 Pages: 123-140

    • DOI

      10.1016/j.pnmrs.2008.07.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Backbone resonance assignments for the cytoplasmic regions of Gprotein-activated inwardly rectifying potassium channel 1(GIRK1)2009

    • Author(s)
      Yokogawa M., Muramatsu T., Takeuchi K., Osawa M., Shimada I.
    • Journal Title

      Biomol. NMR Assign

      Volume: 3(1) Issue: 1 Pages: 125-128

    • DOI

      10.1007/s12104-009-9156-6

    • Data Source
      KAKENHI-PROJECT-21590040
  • [Journal Article] Cross-saturation and transferred cross-saturation experiments2009

    • Author(s)
      Ichio Shimada, el al
    • Journal Title

      Prog.Nuc.Magn.Reson.Spect.

      Volume: 54 Pages: 123-40

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Journal Article] Stable isotope labeling of proteinby Kluyveromyces lactis for NMR study2008

    • Author(s)
      Sugiki T., Shimada I., Takahashi H.
    • Journal Title

      J Biomol NMR 42

      Pages: 159-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Amino acidselective cross-saturation method foridentification of proximal residue pairsin a protein-protein complex2008

    • Author(s)
      Igarashi S., Osawa M., Takeuchi K., Ozawa S., Shimada I.
    • Journal Title

      J Am Chem Soc. 130

      Pages: 12168-12176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Chondroitin sulfate E fragmentsenhance CD44 cleavage andCD44-dependent motility in tumor cells2008

    • Author(s)
      Sugahara K. N., Hirata T., Tanaka T., Ogino S., Takeda M., Terasawa H., Shimada I, Tamura J, ten Dam GB, vanKuppevelt TH, Miyasaka M.
    • Journal Title

      Cancer Res. 68

      Pages: 7191-7199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Carbohydrate bindingmechanism of the macrophagegalactose-type C-type lectin 1 revealedby saturation transfer experiments2008

    • Author(s)
      Sakakura M., Oo-Puthinan S., MoriyamaC., Kimura T., Moriya J., Irimura T., Shimada I.
    • Journal Title

      J Biol Chem 283

      Pages: 33665-33673

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Mechanism of mRNA deadenylation : evidence for a molecular interplaybetween translation termination factoreRF3 and mRNA deadenylases2007

    • Author(s)
      Funakoshi Y, Doi Y, Hosoda N, Uchida N,Osawa M, Shimada I, Tsujimoto M,Suzuki T, Katada T, Hoshino S.
    • Journal Title

      Genes Dev. 21(23)

      Pages: 3135-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Nickel binding to NikA : anadditional binding site reconcilesspectroscopy, calorimetry andcrystallography2007

    • Author(s)
      Addy C, Ohara M, Kawai F, Kidera A,Ikeguchi M, Fuchigami S, Osawa M,Shimada I, Park SY, Tame JR andHeddle JG.
    • Journal Title

      Acta Crystallogr D BiolCrystallogr 63

      Pages: 221-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Backboneresonance assignments for theperiplasmic chaperone LolA fromEscherichia coli2007

    • Author(s)
      Nakada S, Takahashi H, Sakakura M,Kurono M and Shimada I.
    • Journal Title

      Biomolecular NMRAssignments 1

      Pages: 125-127

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] PairwiseNMR Experiments for theDetermination of Protein BackboneDihedral Angle Based onCross-Correlated Spin Relaxation.2007

    • Author(s)
      Takahashi H and Shimada I.
    • Journal Title

      JBiomol NMR 37

      Pages: 179-185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Structural basisof the transition-state stabilization inantibody-catalyzed hydrolysis2007

    • Author(s)
      Sakakura M, Takahashi H, Shimba N,Fujii I, and Shimada I.
    • Journal Title

      J Mol Biol 367

      Pages: 133-147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Structural Basis of the Collagen-binding Mode of Discoidin Domain Receptor 2.2007

    • Author(s)
      O. Ichikawa, M. Osawa, N. Nishida, N. Goshima, N. Nomura, I. Shimada
    • Journal Title

      EMBO.J. 26

      Pages: 4168-4176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083101
  • [Journal Article] Structural Basis of the Collagen-binding Mode of Discoidin Domain Receptor 22007

    • Author(s)
      Osamu Ichikawa, Masanori Osawa, Noritaka Nishida, Naoki Goshima, Nobuo Nomura, and Ichio Shimada
    • Journal Title

      EMBO J. 26

      Pages: 4168-4176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Bovin NV and Irimura T. The aminoacids involved in the distinctcarbohydrate specificities betweenmacrophage galactose-type C-typelectins 1 and 2 (CD301a and b) of mice2007

    • Author(s)
      Oo-puthinan S, Maenuma K, SakakuraM, Denda-Nagai K, Tsuiji M, Shimada I, Nakamura-Tsuruta S, and Hirabayashi S.
    • Journal Title

      Biochim Biophys Acta 1780(2)

      Pages: 89-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Structuralbasis of the collagen-binding mode ofdiscoidin domain receptor 22007

    • Author(s)
      Ichikawa O, Osawa M, Nishida N,Goshima N, and Shimada I.
    • Journal Title

      EMBO J 26

      Pages: 4168-4176

    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Backboneresonance assignment for the outermembrane lipoprotein receptor LolBfrom Escherichia coli2007

    • Author(s)
      Nakada S, Sakakura M, Takahashi H,Tokuda H and Shimada I.
    • Journal Title

      BiomolecularNMR Assignments 1

      Pages: 121-123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19590037
  • [Journal Article] Ligand-induced structural change of the CD44 hyaluronan-binding domain revealed by NMR2006

    • Author(s)
      Mitsuhiro Takeda, Shinji Ogino, Ryo Umemoto, Masayoshi Sakakura, Masahiro Kajiwara, Kazuki Sugahara, Hiroto Kawashima, Masayuki Miyasaka, Hiroaki Terasawa, and Ichio Shimada
    • Journal Title

      J Biol Chem. 281

      Pages: 40089-40095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Conformational dynamics of complementary determining region H3 of an anti-dansyl Fvfragment in the presence of its hapten2005

    • Author(s)
      M.Nakasako, I.Shimada 他
    • Journal Title

      J.Mol.Biol 351

      Pages: 627-640

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Conformational dynamics of complementary determining region H3 of an anti-dansyl Fvfragment in the presence of its hapten2005

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Mol.Biol 351

      Pages: 627-640

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Bead-linked proteoliposomes : a reconstitution method for NMR analyses of membrane protein-ligand interactions2005

    • Author(s)
      M.Yokogawa, I.Shimada 他
    • Journal Title

      J.Am.Chem.Soc. 127

      Pages: 12021-12027

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Bead-linked proteoliposomes : a reconstitution method for NMR analyses of membrane protein-ligand interactions2005

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Am.Chem.Soc. 127

      Pages: 12021-12027

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] An NMR Method for the Determination of Protein Binding Interface Using Dioxygen-Induced Spin-Lattice Relaxation Enhancement2005

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Am.Chem.Soc. 127

      Pages: 5826-5882

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Bead-linked proteoliposomes : a reconstitution method for NMR analyses of membrane protein-ligand interactions2005

    • Author(s)
      Mariko Yokogawa, Koh Takeuchi, and Ichio Shimada
    • Journal Title

      J. Am. Chem. Soc. 127

      Pages: 12021-12027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] An NMR Method for the Determination of Protein Binding Interfaces Using Dioxygen-Induced Spin-Lattice Relaxation Enhancement2005

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Am.Chem.Soc. 127

      Pages: 5826-5832

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] NMR techniques for identifying the interface of a larger protein-protein complex : cross-salutation and transferred cross-saturation experiments.2004

    • Author(s)
      Ichio Shimada
    • Journal Title

      Method. Enzymol. 394

      Pages: 483-506

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] NMR analyses for protein-protein interactions2004

    • Author(s)
      Ichio Shimada
    • Journal Title

      Tanpakushitsu Kakusan Koso 49

      Pages: 1727-1734

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] NMR techniques for identifying the interface of a larger protein-protein complex : cross-salutation and transferred cross-saturation experiments2004

    • Author(s)
      I.Shimada
    • Journal Title

      Method. Enzymol. 394

      Pages: 483-506

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] NMR techniques for identifying the interface of a larger protein-protein complex : cross-salutation and transferred cross-saturation experiments2004

    • Author(s)
      I.Shimada
    • Journal Title

      Method.Enzymol. 394

      Pages: 483-506

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] NMR analyses for protein-protein interactions2004

    • Author(s)
      I.Shimada
    • Journal Title

      Tanpakushitsu Kakusan Koso 49

      Pages: 1727-1734

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Novel Collagen-Binding Mode of the VWA Domain Determined by a Transferred Cross-Saturation Experiment2003

    • Author(s)
      Noritaka Nishida, Hiromi Sumikawa, Masayoshi Sakakura, Nobuhisa Shimba, Hideo Takahashi, Hiroaki Terasawa, Ei-ichiro Suzuki, Ichio Shimada
    • Journal Title

      Nature Struct. Biol. 10

      Pages: 53-58

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] NMR techniques for identifying the interface of a larger protein -protein complex : cross-salutation and transferred cross-saturation experiments

    • Author(s)
      Ichio Shimada
    • Journal Title

      Method.Enzymol (In press)

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Rapid preparation of stable isotope labeled peptides that bind to target proteins by a phage library system

    • Author(s)
      Y.Mizukoshi, I.Shimada 他
    • Journal Title

      J.Biomol.NMR. (in press.)

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Utilization of Methyl Proton Resonances in Cross-saturation Measurements

    • Author(s)
      H.Takahashi, I.Shimada 他
    • Journal Title

      J.Biomol.NMR. (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] NMR techniques for identifying the interface of a larger protein-protein complex : cross-salutation and transferred cross-saturation experiments

    • Author(s)
      Ichio Shimada
    • Journal Title

      Method.Enzymol (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Backbone resonance assignments for the Fv fragment of catalytic antibody 6D9 complexed with a transition state analogue

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Biomol.NMR (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Rapid preparation of stable isotope labeled peptides that bind to target proteins by a phage library system

    • Author(s)
      Y.Mizukoshi, I.Shimada 他
    • Journal Title

      J.Biomol.NMR. (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Utilization of Methyl Proton Resonances in Cross-saturation Measurements

    • Author(s)
      H.Takahashi, I.Shimada 他
    • Journal Title

      J.Biomol.NMR. (in press)

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Backbone resonance assignments for the Fv fragment of catalytic antibody 6D9 complexed with a transition state analogue

    • Author(s)
      M.Sakakura, I.Shimada 他
    • Journal Title

      J.Biomol.NMR (in press)

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Direct determination of interface between membrane and peptide using NMR cross-saturation method

    • Author(s)
      T.Nakamura, I.Shimada 他
    • Journal Title

      Biophys.J. (in press)

    • Data Source
      KAKENHI-PROJECT-15083202
  • [Journal Article] Direct determination of interface between membrane and peptide using NMR cross-saturation method

    • Author(s)
      T.Nakamura, I.Shimada 他
    • Journal Title

      Biophys.J. (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Journal Article] Identification and characterization of a second chromophore of DNA photolyase from Thermus thermophilus HB27

    • Author(s)
      T.Ueda, I.Shimada 他
    • Journal Title

      J.Biol.Chem (in press)

    • Data Source
      KAKENHI-PROJECT-14104017
  • [Patent] インスリン受容体活性化物質のスクリーニング方法2005

    • Inventor(s)
      中村 壮史, 榛葉 信久, 鈴木 榮一郎, 高橋 栄夫, 嶋田 一夫
    • Industrial Property Rights Holder
      中村 壮史, 榛葉 信久, 鈴木 榮一郎, 高橋 栄夫, 嶋田 一夫
    • Industrial Property Number
      2005-176573
    • Filing Date
      2005-06-16
    • Data Source
      KAKENHI-PROJECT-17035020
  • [Presentation] Function-related dynamics of GPCR by NMR2021

    • Author(s)
      Ichio Shimada
    • Organizer
      Pacifichem
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related Dynamics of GPCRs2021

    • Author(s)
      Ichio Shimada
    • Organizer
      ISMAR-APNMR-NMRSJ2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related Dynamics of G-protein-coupled Receptors2021

    • Author(s)
      Ichio Shimada
    • Organizer
      RIKEN BDR Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-Related Dynamics of Membrane Proteins by NMR2021

    • Author(s)
      Ichio Shimada
    • Organizer
      Xingda Lecture
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Membrane protein function by NMR2021

    • Author(s)
      Ichio Shimada
    • Organizer
      PDB 50th Anniversary Symposium in Asia
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in situ 動的構造からみたタンパク質の機能解明と超高磁場への期待2020

    • Author(s)
      嶋田一夫
    • Organizer
      よこはまNMR研究会 第65回ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in situ function-related dynamical analyses of proteins2020

    • Author(s)
      嶋田一夫
    • Organizer
      第59回 NMR討論会(2020)
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Structural equilibrium underlying ligand-dependent activation of GPCR2020

    • Author(s)
      Ichio Shimada
    • Organizer
      "Emerging Topics in Biomolecular Magnetic Resonance" seminar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Conformational equilibrium defines variable transcriptional repression of a multidrug binding transcriptional repressor, QacR2019

    • Author(s)
      Koh Takeuchi, Imai Misaki, and Ichio Shimada
    • Organizer
      The 8th Asia-Pacific NMR symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in-cell NMR法を用いた細胞内生命反応のリアルタイム観測2019

    • Author(s)
      西田紀貴 嶋田一夫
    • Organizer
      よこはまNMR研究会 第62回ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Targeting the cryptic sites: NMR-based strategy to improve the draggability of proteins by controlling the conformational equilibrium2019

    • Author(s)
      Koh Takeuchi, Yumiko Mizukoshi, Yuji Tokunaga, Hitomi Matsuo, Takeshi Takizawa, Hiroyuki Hanzawa, and Ichio Shimada.
    • Organizer
      第57 回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins2019

    • Author(s)
      嶋田一夫
    • Organizer
      日本薬学会・韓国薬学会合同シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] NMR for high-molecular-weight proteins2019

    • Author(s)
      嶋田一夫
    • Organizer
      第58回NMR討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 構造平衡制御によるタンパク質のドラッガビリティの改善2019

    • Author(s)
      竹内恒,水越弓子,德永裕二,滝沢剛,半沢 宏之、嶋田一夫
    • Organizer
      第58回NMR討論会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins2019

    • Author(s)
      Ichio Shimada
    • Organizer
      PSJ-PSK Joint Symposium, Anual meeting of PSJ
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Conformational equilibrium defines transcriptional repression of multidrug binding transcriptional repressors2019

    • Author(s)
      竹内恒,水越弓子,德永裕二,滝沢剛,半沢 宏之、嶋田一夫
    • Organizer
      日本分子生物学会年会 2019
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Real-time observation of the biological events within living cells using in-cell NMR2019

    • Author(s)
      Noritaka Nishida, Ichio Shimada
    • Organizer
      The 8th Asia-Pacific NMR symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of proteins -G protein signaling-2019

    • Author(s)
      嶋田一夫
    • Organizer
      The 8th Asia-Pacific NMR Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2019

    • Author(s)
      Takumi Ueda, Ichio Shimada
    • Organizer
      The 8th Asia-Pacific NMR symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Gタンパク質共役型受容体のシグナル伝達制御機構の解明2019

    • Author(s)
      白石 勇太郎 夏目 芽依 幸福 裕 今井 駿輔 中田 國夫 水越 利巳 上田 卓見 岩井 秀夫 嶋田 一夫
    • Organizer
      日本薬学会第139年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of GPCR by NMR2019

    • Author(s)
      嶋田一夫
    • Organizer
      第100回日本化学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] NMRによる膜タンパク質のin situ機能解明2018

    • Author(s)
      嶋田一夫
    • Organizer
      平成29年度第2回生物構造学研究会、神楽坂
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] NMR法により解明した、マルチドメイン蛋白質複合体CheA-CheYの動的ドメイン間相互作用による走温性制御機構2018

    • Author(s)
      上田卓見、湊雄一、町山麻子、岩井秀夫、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Studying Proteins inside Eukaryotic Cells in NMR2018

    • Author(s)
      嶋田一夫
    • Organizer
      The 62nd Annual Meeting Biophysical Society, San Francisco
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 酸化ストレスに対する細胞内Trxの細胞応答のin-cell NMR観測2018

    • Author(s)
      望月綾野、佐宗新、久保智史、西田紀貴、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 区分同位体標識を用いたβ2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018

    • Author(s)
      白石勇太郎、夏目芽依、幸福裕、今井駿輔、中田國夫、水越利巳、上田卓見、岩井秀夫、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] β2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018

    • Author(s)
      夏目芽依、白石勇太郎、幸福裕、今井駿輔、中田國夫、水越利巳、上田卓見、岩井秀夫、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of proteins-G protein and arrestins signaling by GPCR2018

    • Author(s)
      Ichio Shimada
    • Organizer
      2.International Conference on Magnetic Resonance in Biological Systems 2018 (プレナリー講演)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 昆虫細胞発現系におけるアラニン選択的安定同位体標識法の開発と脂質二重膜中のβ2-アドレナリン受容体への応用2018

    • Author(s)
      中田國夫、五十嵐俊介、幸福裕、上田卓見、白石勇太郎、夏目芽依、横溝智貴、今井俊輔、水越利巳、鈴木榮一郎、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 多剤耐性転写制御の動的構造機能解析2018

    • Author(s)
      竹内恒 嶋田一夫
    • Organizer
      第18回蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] ゲノム編集技術を活用した細胞内Rasの活性制御機構のin-cell NMR観測2018

    • Author(s)
      Qingci Zhao, 藤宮璃勇, Chris Marshall, 伊倉光彦, 西田紀貴, 嶋田一夫
    • Organizer
      第16回次世代を担う若手のためのフィジカル・ファーマフォーラム(PPF2018)
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Dynamics of Membrane Proteins, -gating mechanism of the ethanol-induced activation of GIRK-2018

    • Author(s)
      Ichio Shimada
    • Organizer
      The 18th World Congress of Basic and Clinical Pharmacology, WCP201
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins -G-protein coupled inwardly rectifying K+ channel-2018

    • Author(s)
      Ichio Shimada
    • Organizer
      The 6th International Symposium on Drug Discovery and Design by NMR
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Developments and applications of novel NMR methods to characterize function-related dynamics of high molecular weight proteins2018

    • Author(s)
      Ichio Shimada
    • Organizer
      XLVII National Congress on Magnetic Resonance (プレナリー講演)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Dynamic structure-guided optimization of ligand using FCT method2018

    • Author(s)
      Koh Takeuchi, Yuji Tokunaga, Yumiko Mizukoshi, Ichio Shimada
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Gタンパク質のファミリー選択的なK+チャネル活性制御機構の構造生物学的解明2018

    • Author(s)
      加納 花穂、外山 侑樹、今井 駿輔、岩橋 優太、間瀬 瑤子、横川 真梨子、大澤 匡範、嶋田 一夫
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] アラニン側鎖メチル基を観測対象としたβ2-アドレナリン受容体のシグナル伝達機構の解明2018

    • Author(s)
      横溝智貴、今井俊輔、幸福裕、上田卓見、白石勇太郎、夏目芽依、中田國夫、五十嵐俊介、水越利巳、鈴木榮一郎、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] カリウムチャネルのミリ秒オーダーの開閉の構造機構の解明2018

    • Author(s)
      岩橋 優太、外山 侑樹、今井 駿輔、大澤 匡範、嶋田 一夫
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 構造平衡により規定される多剤結合転写因子QacRの可変的転写制御2018

    • Author(s)
      竹内恒 嶋田一夫
    • Organizer
      第56回生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] G タンパク質共役型内向き整流性カリウムチャネルのエタノール依存的な活性化機構の解明2018

    • Author(s)
      外山 侑樹 加納 花穂 間瀬 瑶子 横川 真梨子 大澤 匡範 嶋田 一夫
    • Organizer
      第57回NMR討論会(誌上開催)
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in-cell NMR法による細胞内環境下におけるRasの活性状態の評価2018

    • Author(s)
      趙慶慈、藤宮璃勇、Chris Marshall、伊倉光彦、西田紀貴、嶋田一夫
    • Organizer
      日本薬学会第138年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 区分同位体標識を用いたβ2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018

    • Author(s)
      白石 勇太郎 夏目 芽依 幸福 裕 今井 駿輔 中田 國夫 水越 利巳 上田 卓見 岩井 秀夫 嶋田 一夫
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins -G-protein coupled inwardly rectifying K+ channel-2018

    • Author(s)
      Ichio Shimada
    • Organizer
      4.Asian Biophysics Symposium, Australian Society for Biophysic Meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 禁制コヒーレント遷移を用いたリガンドの動的構造最適化2018

    • Author(s)
      竹内恒 水越弓子 德永裕二 滝沢剛 半沢宏之 嶋田一夫
    • Organizer
      第57回NMR討論会(誌上開催)
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] β2アドレナリン受容体のリン酸化によるシグナル制御機構の解明2018

    • Author(s)
      夏目 芽依 白石 勇太郎 幸福 裕 今井 駿輔 中田 國夫 水越 利巳 上田 卓見 岩井 秀夫 嶋田 一夫
    • Organizer
      第91回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] NMRによる膜タンパク質のin situ機能解明2018

    • Author(s)
      嶋田一夫
    • Organizer
      機能タンパク質の構造と機能のダイナミクスとそれに基づく細胞・生体システム作動機構の研究拠点の形成、生理研
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 昆虫細胞発現系における安定同位体標識法の開発とGタンパク質共役型受容体のNMR解析2018

    • Author(s)
      幸福 裕、上田 卓見、奥出 順也、白石 勇太郎、夏目 芽依、横溝 智貴、今井 俊輔、近藤 啓太、水村 拓也、鈴木 志歩、伊藤 寛晃、井上 将行、中田 國夫、五十嵐 俊介、山口 秀幸、水越 利巳、鈴木 栄一郎、嶋田 一夫
    • Organizer
      第20回若手NMR研究会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Developments and applications of novel NMR methods to characterize function-related dynamics of high molecular weight proteins2018

    • Author(s)
      Ichio Shimada
    • Organizer
      Advanced Biological Chemistry Mini-symposium, Institute of Biological Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Real-time observation of the biological events within living cells using in-cell NMR2018

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      JST-Mirai symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins -G-protein coupled inwardly rectifying K+ channel-2018

    • Author(s)
      Ichio Shimada
    • Organizer
      2018 Louis-Jeantet Symposium, Centre Medical Universitaire (CMU)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in-cell NMR法を用いた細胞内生命現象のリアルタイム観測2018

    • Author(s)
      西田紀貴 嶋田一夫
    • Organizer
      日本分子生物学会第41回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Functional dynamics of membrane proteins revealed by NMR2017

    • Author(s)
      上田 卓見、嶋田 一夫
    • Organizer
      第55回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08191
  • [Presentation] Conductance of P2X4 receptor is determined by conformational equilibrium in the transmembrane region2017

    • Author(s)
      Takumi Ueda, Yuichi Minato, Shiho Suzuki, Tomoaki Hara, Yutaka Kofuku, Go Kasuya, Yuichiro Fujiwara, Shunsuke Igarashi, Ei-ichiro Suzuki, Osamu Nureki, Motoyuki Hattori, Ichio Shimada
    • Organizer
      58th Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      Asilomar Conference Grounds, Pacific Grove, CA, USA
    • Year and Date
      2017-03-26
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08191
  • [Presentation] Functional dynamics of proteins by NMR2017

    • Author(s)
      嶋田一夫
    • Organizer
      The Protein Society 31st Annual Symposium, Montreal
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Real-time observation of the biological events within living cells using in-cell NMR2017

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      ConBio2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Functional dynamics of membrane proteins by NMR2017

    • Author(s)
      嶋田一夫
    • Organizer
      Department Seminar, The Scripps Research Institute, La Jolla
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 動的構造解析による多剤耐性転写制御因子の非特異的かつ高親和性な結合メカニズムの解明2017

    • Author(s)
      竹内 恒、今井 美咲、德永 裕二、嶋田 一夫
    • Organizer
      第55回生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Developments and applications of novel NMR methods to characterize functional dynamics of high molecular weight proteins2017

    • Author(s)
      嶋田一夫
    • Organizer
      2017 Taiwan-Japan Biomedical Symposium on Magnetic Resonance、Tainan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 動的構造に着目したGタンパク質共役型受容体の機能解明2017

    • Author(s)
      幸福裕、上田卓見、嶋田一夫
    • Organizer
      第61回日本薬学会関東支部大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] in-cell NMR法による細胞内環境下におけるRasの活性状態の評価2017

    • Author(s)
      趙慶慈、藤宮璃勇、Chris Marshall、伊倉光彦、西田紀貴、嶋田一夫
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Developments and applications of novel NMR methods to characterize functional dynamics of high molecular weight proteins2017

    • Author(s)
      嶋田一夫
    • Organizer
      The 15th Chinese Biophysics Congress, Shanghai
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Function-related dynamics of membrane proteins by NMR2017

    • Author(s)
      嶋田一夫
    • Organizer
      The 4th membrane protein workshop 2017, Taipei
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Functional dynamics of membrane proteins revealed by NMR2017

    • Author(s)
      上田卓見、嶋田一夫
    • Organizer
      蛋白質科学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Real-time observation of the biological events within living cells using in-cell NMR2017

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      第17回日本蛋白質科学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 安定同位体標識法の応用による、蛋白質の動的構造の解明2017

    • Author(s)
      上田卓見、嶋田一夫
    • Organizer
      第56回NMR討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Functional dynamics of proteins by NMR2017

    • Author(s)
      嶋田一夫
    • Organizer
      J-PARK international symposium, Tokai
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 核磁気共鳴法による膜タンパク質のin situ 機能解明2017

    • Author(s)
      嶋田一夫
    • Organizer
      DDSBシンポジウム 構造生命科学のフロンティア、理研
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Dynamic regulation of GDP binding to G proteins revealed by magnetic field-dependent NMR relaxation analyses2017

    • Author(s)
      Hanaho Kano, Yuki Toyama, Yoko Mase, Mariko Yokogawa, Masanori Osawa, and Ichio Shimada
    • Organizer
      2017 Taiwan-Japan Biomedical Symposium on Magnetic Resonance
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Developments and applications of multiple quantum NMR methods to characterize functional dynamics of high molecular weight proteins2017

    • Author(s)
      嶋田一夫
    • Organizer
      The 5th Conference of the Asia Pacific Protein, Bangsean
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 緩和速度の磁場依存性解析によるGタンパク質へのGDP結合の動的制御機構の解明2017

    • Author(s)
      外山 侑樹,加納花穂, 間瀬瑤子, 横川真梨子, 大澤匡範,嶋田一夫
    • Organizer
      第56回NMR討論会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 核磁気共鳴法によるタンパク質のin situ 機能解明2017

    • Author(s)
      嶋田一夫
    • Organizer
      NMR共用プラットフォームシンポジウム -高磁場NMRを核としたプラットフォームの新たな展開-, 理研
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Mechanism of multidrug resistance transcriptional regulation revealed by quantitative dynamic analysis using site-specific isotope labeling2017

    • Author(s)
      竹内 恒、嶋田 一夫
    • Organizer
      第56回日本核磁気共鳴学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] 安定同位体標識法の応用による、蛋白質の動的構造の解明2017

    • Author(s)
      上田 卓見、嶋田 一夫
    • Organizer
      第56回NMR討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08191
  • [Presentation] Gタンパク質のファミリー選択的なK+チャネル活性制御機構の解明2017

    • Author(s)
      加納 花穂, 外山 侑樹, 岩橋 優太, 間瀬 瑶子, 横川 真梨子, 大澤 匡範, 嶋田 一夫
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] Functional dynamics of membrane proteins by NMR2017

    • Author(s)
      嶋田一夫
    • Organizer
      KMRS Award Lecture, Koran Magnetc Resonance Society Annual Meeing, Busan
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] カリウムチャネルのミリ秒オーダーの開閉の構造機構の解明2017

    • Author(s)
      岩橋 優太、外山 侑樹、今井 駿輔、大澤 匡範、嶋田 一夫
    • Organizer
      第17回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-17H06097
  • [Presentation] NMR studies on drug target proteins2015

    • Author(s)
      Ichio Shimada
    • Organizer
      The 4th International Symposium on Drug Discovery and Design by NMR
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2015-02-05
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional dynamics of GPCR in micelles and lipid bilayers2015

    • Author(s)
      Ichio Shimada
    • Organizer
      Advanced Stable Isotopic Labelling for Integrated Structural Biology AILM 2015
    • Place of Presentation
      Grenoble, France
    • Year and Date
      2015-02-03
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] リガンドとの相互作用に伴う膜蛋白質の 動的立体構造変化2015

    • Author(s)
      上田卓見、幸福裕、嶋田一夫
    • Organizer
      第53回生物物理学会
    • Place of Presentation
      金沢大学角間キャンパス、金沢
    • Year and Date
      2015-09-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-25460033
  • [Presentation] 多次元NMRスペクトル再構成法の開発とケモカイン-ケモカイン受容体複合体の転移交差飽和実験への応用2015

    • Author(s)
      上田卓見, 吉浦知絵, 幸福裕, 松本昌彦, 奥出順也, 近藤啓太, 白石勇太郎, 嶋田一夫
    • Organizer
      第54回NMR討論会
    • Place of Presentation
      千葉工業大学津田沼キャンパス、千葉
    • Year and Date
      2015-11-08
    • Data Source
      KAKENHI-PROJECT-25460033
  • [Presentation] Functional Equilibrium of Membrane Proteins by NMR2014

    • Author(s)
      Ichio Shimada
    • Organizer
      Internatinal Connfrence of Magnetic Resonance in Biological Systems
    • Place of Presentation
      Dallas, USA
    • Year and Date
      2014-08-26
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明2014

    • Author(s)
      野﨑智裕, 小澤新一郎, 原田瞳, 木村友美, 大澤匡範, 嶋田一夫
    • Organizer
      日本薬学会 第134年会
    • Place of Presentation
      熊本大学(熊本県熊本市)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Functional Equilibrium of Membrane Proteins2014

    • Author(s)
      Ichio Shimada
    • Organizer
      the EMBO Workshop on “Magnetic Resonance for Cellular Structural Biology”
    • Place of Presentation
      Principina Terra, Italy
    • Year and Date
      2014-06-01
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMR 法による P2X4 受容体の開閉制御機構の解明2014

    • Author(s)
      湊 雄一、鈴木 志歩,幸福 裕,上田 卓見,服部 素之,濡木 理,嶋田 一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 二次点NMRインターフェログラム再構成法の開発およびCCR5のMIP-1α結合様式の解明への応用2014

    • Author(s)
      上田卓見、吉浦知絵、松本昌彦、幸福裕、奥出順也、近藤啓太、白石勇太郎、嶋田一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県・熊本市総合体育館
    • Data Source
      KAKENHI-PROJECT-25460033
  • [Presentation] 脂質二重膜中の脂質による GPCR の活性制御機構の解明2014

    • Author(s)
      水村 拓也、近藤 啓太、幸福 裕、上田 卓見、嶋田 一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR 法による脂質二重膜中における P2X4受容体の動的構造平衡の解明2014

    • Author(s)
      鈴木 志歩,湊 雄一,幸福 裕,上田 卓見,服部 素之,濡木 理,嶋田 一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of Membrane Proteins2014

    • Author(s)
      Ichio Shimada
    • Organizer
      The Spring International Convention of the Pharmaceutical Society of Korea
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-04-17
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] β2 アドレナリン受容体のリン酸化によるシグナル制御機構の解明2014

    • Author(s)
      白石 勇太郎,幸福 裕,上田 卓見,嶋田 一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 二次元NMRインターフェログラム再構成法の開発およびCCR5のMIP-1α結合様式の解明への応用2014

    • Author(s)
      上田卓見、吉浦知絵、松本昌彦、幸福裕、奥出順也、近藤啓太、白石勇太郎、嶋田一夫
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明2014

    • Author(s)
      野﨑智裕, 小澤新一郎, 原田瞳, 木村友美, 大澤匡範, 嶋田一夫
    • Organizer
      日本薬学会 第134年会
    • Place of Presentation
      熊本県熊本市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of Membrane Proteins2013

    • Author(s)
      嶋田一夫
    • Organizer
      Frontiers of NMR in Biology, Keystone Symposia,
    • Place of Presentation
      Snowbird, Utah, USA
    • Year and Date
      2013-01-17
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Elucidation of the transient interaction between ubiquitin and yeast ubiquitin hydrolase by NMR2013

    • Author(s)
      小笠 広起、上田 卓見、松本 昌彦、嶋田 一夫
    • Organizer
      Nagoya Symposium - Frontiers in Structural Physiology
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Alternate Signal Transduction Mechanism of CheA and CheY revealed by NMR2013

    • Author(s)
      湊 雄一、上田 卓見、町山 麻子、岩井 秀夫、嶋田 一夫
    • Organizer
      Nagoya Symposium - Frontiers in Structural Physiology
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによる膜タンパク質の機能解明2013

    • Author(s)
      嶋田一夫
    • Organizer
      よこはまNMR構造生物学研究会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of Membrane Proteins2013

    • Author(s)
      嶋田一夫
    • Organizer
      Frontiers of NMR in Biology, Keystone Symposia
    • Place of Presentation
      Snowbird, Utah, USA
    • Year and Date
      2013-01-17
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR observation of protein-protein interactions in living mammalian cells using a gel encapsulated bioreactor system2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      兵庫県神戸市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Affinity regulation mechanism of microtubule-binding domain of cytoplasmic dynein2013

    • Author(s)
      西田紀貴、宝田理、吉川雅英、嶋田一夫
    • Organizer
      Dynein2013
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] Functional Equilibrium of Membrane Proteins2013

    • Author(s)
      嶋田一夫
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2013-07-24
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] ゲル包埋型バイオリアクターを用いた生細胞内蛋白質間相互作用のNMR観測2013

    • Author(s)
      西田紀貴,嶋田一夫
    • Organizer
      第51回日本生物物理学会年会ワークショップ「過渡的複合体が関わる生命現象の統合的理解」
    • Place of Presentation
      京都府京都市
    • Year and Date
      2013-10-29
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] A gel-encapsulated bioreactor system for NMR studies of protein-protein interactions in living mammalian cells.2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      生物物理学会 第51回年会
    • Place of Presentation
      京都府京都市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] バイオリアクターを用いたin-cell NMR法による細胞内タンパク質間相互作用の観測2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      日本薬学会第133回年会
    • Place of Presentation
      神奈川県横浜市
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] Functional Equilibrium of GPCR2013

    • Author(s)
      嶋田一夫
    • Organizer
      Symposium "Perspectives of NMR in drug discovery"
    • Place of Presentation
      Novartis, Basel, Switzerland
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Affinity regulation mechanism of microtubule-binding domain of cytoplasmic dynein2013

    • Author(s)
      西田紀貴、宝田理、吉川雅英、嶋田一夫
    • Organizer
      Dynein2013
    • Place of Presentation
      兵庫県神戸市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structurral elucidation of the Mg2+-dependent gating mechanism of a Mg2+ transporter MgtE2013

    • Author(s)
      丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
    • Organizer
      Nagoya Symposium - Frontiers in Structural Physiology
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR observation of protein-protein interactions in living mammalian cells using a gel encapsulated bioreactor system2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] ゲル包埋型バイオリアクターを用いた生細胞内蛋白質間相互作用のNMR観測2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      生物物理学会 第51回年会
    • Place of Presentation
      京都府京都市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] イオンチャネルの機能に関連した動的構造2013

    • Author(s)
      今井駿輔、大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内 恒、老木成稔、嶋田一夫
    • Organizer
      第35回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      東京大学(東京都文京区)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] A gel-encapsulated bioreactor system for NMR studies of protein-protein interactions in living mammalian cells. ゲル包埋型バイオリアクターを用いた生細胞内蛋白質間相互作用のNMR観測2013

    • Author(s)
      西田紀貴、嶋田一夫
    • Organizer
      日本生物物理学会第51回年会
    • Place of Presentation
      京都府京都市
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] Functional Equilibrium of GPCR2013

    • Author(s)
      嶋田一夫
    • Organizer
      5th Asia-Pacific NMR Symposium in conjunction with ANZNAG2013
    • Place of Presentation
      Brisbane, Australia
    • Year and Date
      2013-10-24
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRを用いた高分子量タンパク質複合体の相互作用解析法の開発と応用2013

    • Author(s)
      嶋田一夫
    • Organizer
      ワークショップ「原理まで遡って再確認する核磁気共鳴法の実力」第36回日本分子生物学会年会
    • Place of Presentation
      兵庫県神戸市
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural Basis for Regulation of G Protein Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Protein2013

    • Author(s)
      大澤匡範、間瀬瑤子、横川真梨子、竹内恒、嶋田一夫
    • Organizer
      Nagoya Symposium - Frontiers in Structural Physiology
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] バイオリアクターを用いた in-cell NMR 法による細胞内タンパク質間相互作用の観測2013

    • Author(s)
      西田紀貴、久保智史、嶋田一夫
    • Organizer
      日本薬学会 第133回年会
    • Place of Presentation
      神奈川県横浜市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] イオンチャネルの機能に関連した動的構造2013

    • Author(s)
      今井駿輔、○大澤匡範、三田建一郎、豊永翔、町山麻子、上田卓見、竹内 恒、老木成稔、嶋田一夫
    • Organizer
      第35回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      東京都文京区
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによる膜タンパク質の機能解明2013

    • Author(s)
      嶋田一夫
    • Organizer
      よこはまNMR構造生物学研究会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2013-03-22
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Efficacy of the b2-adrenergic receptor is determined by conformational2013

    • Author(s)
      幸福 裕、上田 卓見、奥出 順也、白石 勇太郎、近藤 啓太、前田 正洋、辻下 英樹、嶋田 一夫
    • Organizer
      Nagoya Symposium - Frontiers in Structural Physiology
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of Membrane Proteins2013

    • Author(s)
      嶋田一夫
    • Organizer
      54th Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      Asilomar, California, USA
    • Year and Date
      2013-04-15
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Elucidation of the mechanism of analgesic tolerance by chronic administration of morphine2012

    • Author(s)
      奥出順也*, 吉浦知絵, 白石勇太郎*, 幸福裕, 上田卓見, 嶋田一夫
    • Organizer
      第132回日本薬学会 年会 日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by G protein α subunit in the i/o-family (Gαi/o)2012

    • Author(s)
      間瀬瑤子、横川真梨子、大澤匡範、嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] An NMR method to observe protein-protein interactions in living mammalian cells using the gel encapsulated bioreactor system2012

    • Author(s)
      久保智史, 西田紀貴, 宇田川侑子, 宝田理, 荻野新治, 嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] The effect of tensile force on CD44 mediated cell rolling2012

    • Author(s)
      鈴木隆*、鈴木美穂#、西田紀貴、嶋田一夫
    • Organizer
      第132回日本薬学会 年会 日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of Membrane Proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      The 3rd International Symposium on Drug Discovery and Design by NMR
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2012-10-11
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRを用いた膜タンパク質の機能解明2012

    • Author(s)
      嶋田一夫
    • Organizer
      第11回日本蛋白質科学会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2012-06-22
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] ATP effect on Mg2+-dependent gating of a Mg2+ channel MgtE2012

    • Author(s)
      丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
    • Organizer
      第85回生化学会大会
    • Place of Presentation
      福岡県福岡市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Dynamics of Membrane Proteins by NMR2012

    • Author(s)
      嶋田一夫
    • Organizer
      第85回生化学会年会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] The effect of tensile force on CD44 mediated cell rolling2012

    • Author(s)
      鈴木隆、鈴木美穂、西田紀貴、嶋田一夫
    • Organizer
      第132回日本薬学会年会日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRによる膜タンパク質の機能解明2012

    • Author(s)
      嶋田一夫
    • Organizer
      第34回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      京都府京都市
    • Year and Date
      2012-11-15
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Elucidation of the mechanism of analgesic tolerance by chronic administration of morphine2012

    • Author(s)
      奥出順也, 吉浦知絵, 白石勇太郎, 幸福裕, 上田卓見, 嶋田一夫
    • Organizer
      第132回日本薬学会年会日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Gタンパク質共役型受容体の動的平衡の制御機構の解明2012

    • Author(s)
      近藤 啓太、幸福 裕、上田 卓見、嶋田 一夫
    • Organizer
      第85回日本生化学会年会
    • Place of Presentation
      福岡県福岡市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Elucidation of the affinity switching mechanism of the microtubule-binding domain of cytoplasmic dynein2012

    • Author(s)
      宝田理、西田紀貴、吉川雅英、嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] An NMR method to observe protein-protein interactions in living mammalian cells using the gel encapsulated bioreactor system2012

    • Author(s)
      久保智史, 西田紀貴, 宇田川侑子, 宝田理, 荻野新治, 嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PROJECT-24770090
  • [Presentation] Functional Dynamics of Membrane Proteins by NMR2012

    • Author(s)
      嶋田一夫
    • Organizer
      第85回生化学会年会
    • Place of Presentation
      福岡県福岡市
    • Year and Date
      2012-12-11
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical aspects of membrane proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      INPEC2012
    • Place of Presentation
      台北、台湾
    • Year and Date
      2012-04-06
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 内向き整流性カリウムチャネル開閉機構の解明2012

    • Author(s)
      外山侑樹、大澤匡範、横川真梨子、豊永翔、町山麻子、嶋田一夫
    • Organizer
      第12回日本蛋白質科学会
    • Place of Presentation
      愛知県名古屋市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Dynamics of Membrane Proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      The 3rd International Symposium on Drug Discovery and Design by NM
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2012-10-11
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Elucidation of the affinity switching mechanism of the microtubule-binding domain of cytoplasmic dynein2012

    • Author(s)
      宝田理、西田紀貴、吉川雅英、嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 膜タンパク質を対象としたNMR創薬基盤技術2012

    • Author(s)
      嶋田一夫
    • Organizer
      第25回バイオメディカル分析科学シンポジウム
    • Place of Presentation
      東京都港区
    • Year and Date
      2012-08-09
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRによる膜タンパク質の機能解明2012

    • Author(s)
      嶋田一夫
    • Organizer
      第13回若手NMR研究会
    • Place of Presentation
      北海道、支笏湖
    • Year and Date
      2012-07-20
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Elucidation of the transient interaction between ubiquitin and yeast ubiquitin hydrolase2012

    • Author(s)
      小笠 広起、上田 卓見、松本 昌彦、嶋田 一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] A novel in-cell NMR technique to determine the binding interface of functional protein complexes in mammalian cells2012

    • Author(s)
      久保智史、荻野新治、宇田川侑子、宝田理、西田紀貴、嶋田一夫
    • Organizer
      第132回日本薬学会年会日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 細胞内molecular crowding環境におけるタンパク質間相互作用解析2012

    • Author(s)
      宇田川侑子、久保智史、西田紀貴、嶋田一夫
    • Organizer
      第85回生化学会大会
    • Place of Presentation
      福岡県福岡市
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Elucidation of regulatory mechanism for arrestin activation by G-protein coupled receptor (ポスター)2012

    • Author(s)
      白石勇太郎*, 幸福裕, 奥出順也*, 吉浦知絵, 阿内康平*, 上田卓見, 嶋田一夫
    • Organizer
      第132回日本薬学会 年会 日本薬学会
    • Place of Presentation
      北海道大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Protein-protein docking method utilizing the intermolecular 1H-1H distance restraints obtained by the quantitative cross-saturation method2012

    • Author(s)
      松本 昌彦、上田 真也、上田 卓見、嶋田 一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Elucidation of regulatory mechanism for arrestin activation by G-protein coupled receptor2012

    • Author(s)
      白石勇太郎, 幸福裕, 奥出順也, 吉浦知絵, 阿内康平, 上田卓見, 嶋田一夫
    • Organizer
      第132回日本薬学会年会日本薬学会
    • Place of Presentation
      北海道大学(札幌)(ポスター)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRによる膜タンパク質の機能解明2012

    • Author(s)
      嶋田一夫
    • Organizer
      第34回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      京都大学薬学部京都市
    • Year and Date
      2012-11-15
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Dynamics of Membrane Proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Year and Date
      2012-08-21
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional Dynamics of Membrane Proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      ICMRBS
    • Place of Presentation
      Lyon, France
    • Year and Date
      2012-08-21
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins2012

    • Author(s)
      嶋田一夫
    • Organizer
      INPEC2012
    • Place of Presentation
      台北、台湾
    • Year and Date
      2012-04-06
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Elucidation of the Mg2+-dependent gating mechanism of a Mg2+ transporter MgtE2012

    • Author(s)
      丸山達朗, 今井駿輔, 大澤匡範, 服部素之, 石谷隆一郎, 濡木理, 嶋田一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural Elucidation of the Alternate Signal Transduction Mechanism of CheA and CheY2012

    • Author(s)
      湊 雄一、上田 卓見、町山 麻子、岩井 秀夫、嶋田 一夫
    • Organizer
      25th ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRを用いた膜タンパク質の機能解明2012

    • Author(s)
      嶋田一夫
    • Organizer
      第11回日本蛋白質科学会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2012-06-22
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] A novel in-cell NMR technique to determine the binding interface of functional protein complexes in mammalian cells2012

    • Author(s)
      久保智史*、荻野新治、宇田川侑子*、宝田理#、西田紀貴、嶋田一夫
    • Organizer
      第132回日本薬学会 年会 日本薬学会
    • Place of Presentation
      北海逆大学(札幌)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins2011

    • Author(s)
      小澤新一郎、大澤匡範、木村友美、原田瞳、野崎智裕、嶋田一夫
    • Organizer
      第34回日本分子生物学会年会日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)(ポスター)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      MBSJ2011
    • Place of Presentation
      パシフィコ横浜(横浜)(招待講演)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      The 4th Asia-Pacific NMR Symposium
    • Place of Presentation
      Central Garden Beijing Hotel (北京、中国)(招待講演)
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      AIMECS11
    • Place of Presentation
      京王プラザホテル(東京)(招待講演)
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Analyses of Membrane Proteins by NMR2011

    • Author(s)
      Ichio Shimada
    • Organizer
      The 9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      北海道大学(札幌)(招待講演)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural Mechanism for the Affinity-Regulation of Cytoplasmic Dynein2011

    • Author(s)
      宝田理#, 西田紀貴、吉川雅英、嶋田一夫
    • Organizer
      第34回日本分子生物学会年会 日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)(招待講演)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins2011

    • Author(s)
      小澤新一郎, 大澤匡範, 木村友美, 原田瞳, 野崎智裕, 嶋田一夫
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      The 4th Asia-Pacific NMR Symposium
    • Place of Presentation
      Central Garden Beijing Hotel(北京、中国)(招待講演)
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K+ channels (ポスター)2011

    • Author(s)
      原田瞳#, 大澤匡範, 小澤新一郎#, 木村友美, 野崎智裕*, 嶋田一夫
    • Organizer
      第34回日本分子生物学会年会 日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K^+ channels2011

    • Author(s)
      原田瞳, 大澤匡範, 小澤新一郎, 木村友美, 野崎智裕, 嶋田一夫
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-21590040
  • [Presentation] NMRによる GPCR・リガンド相互作用解析2011

    • Author(s)
      嶋田一夫
    • Organizer
      新学術領域研究「過渡的複合体」公開シンポジウム
    • Place of Presentation
      東京大学薬学部東京
    • Year and Date
      2011-07-21
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural Mechanism for the Affinity-Regulation of Cytoplasmic Dynein2011

    • Author(s)
      宝田理, 西田紀貴、吉川雅英、嶋田一夫
    • Organizer
      第34回日本分子生物学会年会日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural investigation of voltage-sensing mechanism of voltage-dependent K+ channels2011

    • Author(s)
      原田瞳, 大澤匡範, 小澤新一郎, 木村友美, 野崎智裕, 嶋田一夫
    • Organizer
      第34回日本分子生物学会年会日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)(ポスター)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional Analyses of Membrane Proteins by NMR2011

    • Author(s)
      Ichio Shimada
    • Organizer
      The 9th International Symposium for Future Drug Discovery and Medical Care
    • Place of Presentation
      北海道大学(札幌)(招待講演)
    • Year and Date
      2011-09-29
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural basis for the inhibition of voltage-dependent potassium (Kv) channels by gating modifier toxins (ポスター)2011

    • Author(s)
      小澤新一郎#、大澤匡範、木村友美、原田瞳#、野崎智裕*、嶋田一夫
    • Organizer
      第34回日本分子生物学会年会 日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      AIMECS11
    • Place of Presentation
      京王プラザホテル(東京)(招待講演)
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical Aspects of Membrane Proteins2011

    • Author(s)
      Ichio Shimada
    • Organizer
      MBSJ2011
    • Place of Presentation
      パシフィコ横浜(横浜)(招待講演)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Molecular interaction of membrane proteins by NMR2011

    • Author(s)
      Ichio Shimada
    • Organizer
      Functional Proteomics & KIST Symposium
    • Place of Presentation
      Korea Institute of Science and Technology, International Cooperation Bldg(ソウル、韓国)(招待講演)
    • Year and Date
      2011-02-02
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural bases of the interactions between chemokines and their G-protein-coupled receptors2010

    • Author(s)
      嶋田一夫
    • Organizer
      EUROMAR/ISMAR
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによる膜タンパク質の機能解析2010

    • Author(s)
      嶋田一夫
    • Organizer
      日本学術振興会、回折構造生物学第169委員会、第32回研究会
    • Place of Presentation
      ゆうぽうと,東京都
    • Year and Date
      2010-07-20
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによるケモカイン受容体・ケモカイン相互作用解析2010

    • Author(s)
      嶋田一夫
    • Organizer
      第34回阿蘇シンポジウム
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル,熊本県
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 高分子量蛋白質の構造解析に適した安定同位体ラベル法および測定法の開発2010

    • Author(s)
      竹内恒、高橋栄夫、嶋田一夫、Gerhard Wagner
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      船堀タワーホール,東京都
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Frankfurt University seminar
    • Place of Presentation
      Frankfurt, Germany
    • Year and Date
      2010-09-06
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      The International Network of Protein Engineering Centres (INPEC) 2010
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Technische Universitat Munchen/Helmholtz Zentrum Munchen seminar
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Max Planck Institute seminar
    • Place of Presentation
      Gottingen, Germany
    • Year and Date
      2010-10-21
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural bases of the interactions between chemokines and their G-protein-coupled receptors2010

    • Author(s)
      嶋田一夫
    • Organizer
      EUROMAR/ISMAR
    • Place of Presentation
      Florence, Italy
    • Year and Date
      2010-07-06
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] -超高磁場が拓く生体系NMR:最新技術と応用-膜タンパク質のダイナミックスと機能2010

    • Author(s)
      嶋田一夫
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学,大阪府
    • Year and Date
      2010-07-29
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      The International Network of Protein Engineering Centres (INPEC) 2010
    • Place of Presentation
      Uppsala, Sweden
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional analyses of membrane proteins by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 高分子量蛋白質の構造解析に適した安定同位体ラベル法および測定法の開発2010

    • Author(s)
      竹内恒、高橋栄夫、嶋田一夫、Gerhard Wagner
    • Organizer
      第49回NMR討論会
    • Place of Presentation
      船堀タワーホール,東京都
    • Year and Date
      2010-11-15
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Technische Universitat Munchen/Helmholtz Zentrum Munchen seminar
    • Place of Presentation
      Munchen, Germany
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural bases of the interactions between chemokines and their G-protein-coupled receptors2010

    • Author(s)
      嶋田一夫
    • Organizer
      Symposium on Structure and Folding of Disease Related Proteins
    • Place of Presentation
      Seoul National University, Korea
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRによる膜タンパク質の機能解明2010

    • Author(s)
      嶋田一夫
    • Organizer
      構造と機能を基盤とした膜蛋白質研究から覗く未来への展望
    • Place of Presentation
      サントリー研究センター・大阪
    • Year and Date
      2010-01-19
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによる膜タンパク質の機能解析2010

    • Author(s)
      嶋田一夫
    • Organizer
      日本学術振興会、回折構造生物学第169委員会、第32回研究会
    • Place of Presentation
      ゆうぽうと,東京都
    • Year and Date
      2010-07-20
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 過渡的複合体が関わる生命現象の統合的理解2010

    • Author(s)
      嶋田一夫
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター,北海道
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMR法によるactinとactin結合タンパク質との相互作用解析法の開発2010

    • Author(s)
      黄淑嫻、梅本良、上田太郎、西田紀貴、嶋田一夫
    • Organizer
      第33回日本分子生物学会年会 第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド,兵庫県
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] 過渡的複合体が関わる生命現象の統合的理解2010

    • Author(s)
      嶋田一夫
    • Organizer
      第10回日本蛋白質科学会年会ワークショップ「過渡的複合体の視点から生命現象を捉えなおす」
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural bases of the interactions between chemokines and their G-protein-coupled receptors2010

    • Author(s)
      嶋田一夫
    • Organizer
      Symposium on Structure and Folding of Disease Related Proteins
    • Place of Presentation
      Seoul National University, Korea
    • Year and Date
      2010-07-10
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 過渡的複合体が関わる生命現象の統合的理解2010

    • Author(s)
      嶋田一夫
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌コンベンションセンター,北海道
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによるケモカイン受容体・ケモカイン相互作用解析2010

    • Author(s)
      嶋田一夫
    • Organizer
      第34回阿蘇シンポジウム
    • Place of Presentation
      阿蘇リゾートグランヴィリオホテル,熊本県
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRを用いた膜タンパク質の機能解明2010

    • Author(s)
      嶋田一夫
    • Organizer
      日本分光学会NMR分光部会シンポジウム
    • Place of Presentation
      東京大学,東京都
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Frankfurt University seminar
    • Place of Presentation
      Frankfurt, Germany
    • Year and Date
      2010-09-06
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRを用いた膜タンパク質の機能解明2010

    • Author(s)
      嶋田一夫
    • Organizer
      日本分光学会NMR分光部会シンポジウム
    • Place of Presentation
      東京大学,東京都
    • Year and Date
      2010-09-08
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR法によるactinとactin結合タンパク質との相互作用解析法の開発2010

    • Author(s)
      黄淑嫻、梅本良、上田太郎、西田紀貴、嶋田一夫
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド,兵庫県
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] 創薬研究と構造生物学2010

    • Author(s)
      嶋田一夫
    • Organizer
      EMP
    • Place of Presentation
      東京大学・東京
    • Year and Date
      2010-01-09
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Dynamical aspects of membrane proteins2010

    • Author(s)
      嶋田一夫
    • Organizer
      Max Planck Institute seminar
    • Place of Presentation
      Gottingen, Germany
    • Year and Date
      2010-10-21
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional analyses of membrane proteins by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      COLD SPRING HARBOR ASIA CONFERENCES
    • Place of Presentation
      Suzhou, China
    • Year and Date
      2010-05-13
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] -超高磁場が拓く生体系NMR:最新技術と応用-膜タンパク質のダイナミックスと機能2010

    • Author(s)
      嶋田一夫
    • Organizer
      大阪大学蛋白質研究所セミナー
    • Place of Presentation
      大阪大学,大阪府
    • Year and Date
      2010-07-29
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] The 2nd International Symposium on Drug Discovery and Design by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      Functional analyses of membrane proteins by NMR
    • Place of Presentation
      横浜市立大学,神奈川県
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] The 2nd International Symposium on Drug Discovery and Design by NMR2010

    • Author(s)
      嶋田一夫
    • Organizer
      Functional analyses of membrane proteins by NMR
    • Place of Presentation
      横浜市立大学,神奈川県
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR studies of the interactions between membrane proteins and their ligands2009

    • Author(s)
      嶋田一夫
    • Organizer
      Structural biology seminar
    • Place of Presentation
      Vanderbilt University, USA
    • Year and Date
      2009-11-18
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMRによるリガンド・受容体相互作用解析2009

    • Author(s)
      嶋田一夫
    • Organizer
      第一回シグナルネットワーク研究会
    • Place of Presentation
      東京大学・東京
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Protein recognition by NMR2009

    • Author(s)
      Ichio Shimada
    • Organizer
      International Network of Protein Engineering Conference
    • Place of Presentation
      Itamambuca, Brasil
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Protein recognition by NMR2009

    • Author(s)
      嶋田一夫
    • Organizer
      INPEC2009
    • Place of Presentation
      Itamambuca, Brasil
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Theoretical Analysis and Application of Transferred Cross-saturation Methods2008

    • Author(s)
      Ichio Shimada
    • Organizer
      the 49th ENC, Asilomar, California
    • Place of Presentation
      USA
    • Year and Date
      2008-03-14
    • Data Source
      KAKENHI-PROJECT-15083101
  • [Presentation] NMR Study on Membrane proteins-ligands2007

    • Author(s)
      嶋田一夫
    • Organizer
      Interactions-Application of Transferred Cross Saturation- AIMECS 07, the 6th International Medicinal Chemistry Symposium
    • Place of Presentation
      Istanbul, Turkey
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Presentation] NMR study on protein-protein interactions using paramagnetic probe2007

    • Author(s)
      嶋田一夫
    • Organizer
      International Workshop on Perspectives on Stable Isotope Aided NMR Methods for Protein Structural Analysis
    • Place of Presentation
      Osaka, Japan
    • Data Source
      KAKENHI-PROJECT-15083202
  • [Presentation] Gタンパク質三量体によるGタンパク質共役型内向き整流性カリウムチャネル活性制御機構の構造生物学的解明

    • Author(s)
      加納 花穂, 外山 侑樹, 岩橋 優太, 間瀬 瑶子, 横川 真梨子, 大澤 匡範, 嶋田 一夫
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] 電位依存性カリウムイオンチャネルの膜電位感受機構の解明

    • Author(s)
      野﨑智裕、小澤新一郎、原田瞳、木村友美、大澤匡範、嶋田一夫
    • Organizer
      第12回次世代を担う若手のためのフィジカル・ファーマフォーラム
    • Place of Presentation
      箱根高原ホテル(神奈川県足柄下郡)
    • Year and Date
      2014-07-14 – 2014-07-15
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] NMR を用いた高分子量タンパク質複合体の相互作用解析法の開発と応用

    • Author(s)
      嶋田一夫
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      兵庫県神戸市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium

    • Author(s)
      Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
    • Organizer
      日本生生物物理学会年会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Functional Equilibrium of GPCR

    • Author(s)
      嶋田一夫
    • Organizer
      Symposium “Perspectives of NMR in drug discovery
    • Place of Presentation
      Novartis, Basel, Switzerland
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] メチルTROSY法による膜タンパク質の機能調節メカニズムの解明

    • Author(s)
      大澤匡範, 今井駿輔, 竹内 恒, 嶋田一夫
    • Organizer
      NMR討論会
    • Place of Presentation
      大阪大学(大阪府吹田市)
    • Year and Date
      2014-11-04 – 2014-11-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Structural Basis for Regulation of G Protein-activated Inwardly Rectifying Potassium Channel 1 (GIRK1) by G Proteins

    • Author(s)
      Osawa M, Mase Y, Yokogawa M,Takeuchi K, Shimada I
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Dallas (USA)
    • Year and Date
      2014-08-24 – 2014-08-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Functional Equilibrium of Membrane Proteins

    • Author(s)
      嶋田一夫
    • Organizer
      Frontiers of NMR in Biology, Keystone Symposia,
    • Place of Presentation
      Snowbird, Utah, USA
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel

    • Author(s)
      Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
    • Organizer
      Program for Young Researcher Symposium in Europe
    • Place of Presentation
      Oxford (英国)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Functional Dynamics of Membrane Proteins

    • Author(s)
      嶋田一夫
    • Organizer
      ICMRBS
    • Place of Presentation
      リヨン、フランス
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Dynamics of Membrane Proteins

    • Author(s)
      嶋田一夫
    • Organizer
      The 3rd International Symposium on Drug Discovery and Design by NM
    • Place of Presentation
      神奈川県横浜市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel

    • Author(s)
      Y. Toyama, M. Osawa, M. Yokogawa, S. Toyanaga, A, Machiyama, I. Shimada
    • Organizer
      第12回 日本蛋白質科学会年会
    • Place of Presentation
      名古屋国際会議場 (愛知)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] NMRによる膜タンパク質の機能解明

    • Author(s)
      嶋田一夫
    • Organizer
      第13回若手NMR研究会
    • Place of Presentation
      北海道、支笏湖
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Structural Elucidation of Mg2+-dependent Gating Mechanism of a Mg2+ Transporter MgtE

    • Author(s)
      T. Maruyama, S. Imai, M. Osawa, M. Hattori, R. Ishitani, O. Nureki, I. Shimada
    • Organizer
      The XXVth International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Lyon (フランス)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] ATP effect on Mg2+-dependent gating of a Mg2+ channel MgtE

    • Author(s)
      T. Maruyama, S. Imai, M. Osawa, M. Hattori, R. Ishitani, O. Nureki, I. Shimada
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Functional Equilibrium of Membrane Proteins

    • Author(s)
      嶋田一夫
    • Organizer
      International Conference on Structural Genomics 2013
    • Place of Presentation
      北海道札幌市
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional Equilibrium of Membrane Proteins

    • Author(s)
      嶋田一夫
    • Organizer
      54th Experimental Nuclear Magnetic Resonance Conference
    • Place of Presentation
      Asilomar, California, USA
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Structural analyses of the gating mechanism of inwardly rectifying potassium channel

    • Author(s)
      Toyama Y, Osawa M, Yokogawa M, Shimada I
    • Organizer
      International Conference on Magnetic Resonance in Biological Systems
    • Place of Presentation
      Dallas (USA)
    • Year and Date
      2014-08-24 – 2014-08-29
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] Structural basis for the modulation of the gating property of G protein-gated inwardly rectifying potassium ion channel (GIRK) by the i/o-family G protein α subunit (Gαi/o)

    • Author(s)
      Yoko Mase, Mariko Yokogawa, Masanori Osawa, and Ichio Shimada
    • Organizer
      The XXVth International Conference on Magnetic Resonance in Biological Systems (ICMRBS)
    • Place of Presentation
      Lyon (フランス)
    • Data Source
      KAKENHI-PROJECT-24590048
  • [Presentation] 膜タンパク質を対象としたNMR創薬基盤技術

    • Author(s)
      嶋田一夫
    • Organizer
      第25回バイオメディカル分析科学シンポジウム
    • Place of Presentation
      東京都港区
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] NMR を用いた高分子量タンパク質複合体の相互作用解析法の開発と応用

    • Author(s)
      嶋田一夫
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      兵庫県神戸市
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] Functional Equilibrium of GPCR

    • Author(s)
      嶋田一夫
    • Organizer
      Symposium “Perspectives of NMR in drug discovery
    • Place of Presentation
      Novartis, Basel, Switzerland
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
  • [Presentation] Functional Equilibrium of GPCR

    • Author(s)
      嶋田一夫
    • Organizer
      5th Asia-Pacific NMR Symposium in conjunction with ANZNAG2013
    • Place of Presentation
      Brisbane, Australia
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21121001
  • [Presentation] NMRによる膜タンパク質の機能解明

    • Author(s)
      嶋田一夫
    • Organizer
      第34回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      京都府京都市
    • Invited
    • Data Source
      KAKENHI-PLANNED-21121002
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    # of Collaborated Products: 2 results
  • 2.  OSAWA Masanori (60361606)
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    # of Collaborated Products: 58 results
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  • 145.  間瀬 瑶子
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  • 146.  紺谷 圏二
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  • 147.  遠田 悦子
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