Maeda Hiroshi 前田浩

… Alternative Names

MAEDA Hiroshi 前田浩

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Researcher Number	90004613
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2018 – 2020: 大阪大学, 医学系研究科, 招へい教授 2016 – 2018: 崇城大学, DDS研究所, 特任教授 2005 – 2010: 崇城大学, 薬学部, 教授 1986 – 2002: 熊本大学, 医学部, 教授 1986: 熊本大, 医学部, 教授 1985: 熊本大学, 医, 教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Biological Sciences / Pathological medical chemistry / Gastroenterology / Anesthesiology/Resuscitation studies / 応用薬理学・医療系薬学 / Virology / Physical pharmacy Except Principal Investigator Biological Sciences / General pharmacology … More / Pathological medical chemistry / Virology / Physical pharmacy / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Pediatrics / Respiratory organ internal medicine / Biophysics Less
Keywords	Principal Investigator NO / パーオキシナイトライト / 一酸化窒素 / 高分子制癌剤 / ブラジキニン / スマンクス / 遺伝子変異 / EPR効果 / 発癌 / ウイルス感染病態 … More / フリーラジカル / 病原因子 / 細菌性プロテアーゼ / DDS / 油性制癌剤 / 腫瘍血管 / 組織修復 / 組織破壊 / マトリックスメタロプロテアーゼ / 固型腫瘍 / 腫瘍選択性 / 癌性腹水 / 腫瘍血管透過性 / peroxynitrite / bacterial invasion / bacterial protease / 敗血症 / matrix metalloproteinase / 活性酵素 / 活性酸素 / インフルエンザウイルス / リピオドール / 高分子型制癌剤 / iNOS欠損マウス / 細胞保護作用 / 抗アポトーシス作用 / アポトーシス / ネズミチフス菌 / 感染防御 / 血管透過性亢進 / 骨髄毒性 / 効果増強 / 昇圧化学療法 / Liver function / Hepatitis / Fluminant hepatitis / Polyethylene glycol conjugate / Bilirubin oxidase / Kernicterus / Jaundice / Bilirubin / PEG結合酵素 / ポリエチレングリコール結合型酵素製剤 / 減黄療法 / 新生児核黄疸 / 肝不全 / ポリエチレングリコ-ル結合型酵素 / 肝硬変 / 黄疽 / 激症肝炎 / 核黄疸 / 肝機能 / ポリエチレングリコ-ル結合酵素 / ビリルビン分解酵素 / 肝炎 / 黄疸 / ビリルビン / INOS-DEFICIENT MICE / CYTOPROTECTIVE EFFECT / ANTI-APOPTOTIC EFFECT / APOPTOSIS / MURINE SALMONELLOSIS / HOST DEFENSE / PEROXYNITRITE / 免疫抑制 / Helicobacter pylori / nitroguanosine / carcinogenesis / viral pathogenesis / genomic mutation / nitric oxide / free radical / バーオキシナイトライト / anti-oxidant / anti-apoptosis / cytoprotection / nitrosothiol / NO scavenger / endotoxin / ニトロソα_1-プロテアーゼインヒビター / 抗ショック剤 / ニトロソα1-プロテアーゼインヒビター / NO消去剤 / エンドトキシンショック / free radicals / bacterial pathogenesis / MMP / liver metastasis / colon cancer / preventive adjuvant chemotherapy / arterial injection / new concept in cancer chemotherapy / EPR effect / hepatoma / Lipiodol / SMANCS / 遺伝子治療 / 画像診断 / X線-CT / 固型癌 / 予防補助化学療法 / 転移性肝癌 / 動注療法 / 最大耐量のコンセプトの問題 / 腫瘍サイズ依存性 / 癌治療の新しいコンセプト / 肝癌 / septic shock / sepsis / matrix metalloprotease / bradykinin / ブラジキニンアンタゴニスト / 浮腫 / S.pyogenes protease / Vibrio vulnificus / 好中球プロコラゲナーゼ / 大豆トリプシンインヒビター / 敗血症ショック / Environmental factors / Mite protease / Host's factors / Bradykinin / Free radicals / ダニプロテア-ゼ / 環境因子 / ハウスダスト / ダニプロテアーゼ / 補体 / Chronic viral diseases / Chronic viral hepatitis / Radical scavenger / Superoxide dismutase / Free radical / Active oxygens / Pathogenesis / Influenza virus / 複合感染 / プロテア-ゼ / 慢性ウイルス疾患 / 慢性ウイルス肝炎 / ラジカルスカベンジャ- / フリ-ラジカル / ス-パ-オキシドディスムタ-ゼ / 病因論 / 腫瘍の脈管特性 / ヒドロプロリルブラジキニン / 血管透過性因子 / 腫瘍血管の透過性 / EPRー効果 / リピオドール制癌剤 / 磁性化酵素 / 腸癌の肝転移の防止 / 腫瘍ダーゲティング / マイトマイシン・デキストラン結合物 / ピランコポリマー・アドリアマイシン結合物 / リンパ節転移 / 肝転移の予防 / デキストラン-マイトマイシン / ピラン結合アドリアシン / 腫瘍親和性制癌背 / デキストラン結合 / ピラン結合制癌剤 / PEG-アスパラギナーゼ / 油性化制癌剤 / 高分子結合制癌剤 / NOの寿命 / PEG化医薬 / ナノメディシン / NOの寿命延長 / 水可溶化 / 降圧剤 / 徐放性 / XO阻害剤 / ドラッグデリバリー / 腫瘍ターゲティング / 腫瘍ターゲラィング / PEG化制癌剤 / 新しい光化学療法 / Znプロトポルフィリン / 腫瘍ターゲッティング / HO-1阻害剤 / HSP32阻害剤 / SMA-ミセル化制癌剤 / HSP-32 / 光増感療法 / PEG-ZnP(亜鉛プロトポルフィリン) / D-アミノ酸酸化酵素 / ZnPP / HSP32 / HO-1 / オキシストレス誘導 / 高分子化製剤 / ミセル化製剤 / EPR-効果 / 塩基損傷 / 活性酸化窒素 / 8-ニトログアノシン / 薬剤耐性 / ヘリコバクターピロリ遺伝子 / ニトログアノシン / グルタチオン / プラスタグランディン / 高分子薬物 / 電子スピン共鳴法 / 癌化学療法 / チトクロームP-450還元酵素 / キニンアンタゴニスト / プロスタグランジン / ブリジキニン / 血管透過性 / ターゲッティング / タ-ゲッティング / キニン分解酵素阻害剤 / 癌の脈管特性 / カリクレイン … More Except Principal Investigator NO / パーオキシナイトライト / 一酸化窒素 / フリーラジカル / ドラッグデリバリーシステム / オリザシスタチン / 酸素ラジカル / ウイルス感染病態 / PEROXYNITRITE / ニトロソチオール / HPLC / NITRATIVE STRESS / 8-ニトログアノシン / viral pathogenesis / peroxynitrite / free radicals / スーパーオキサイド / EPR効果 / グルタチオン / マトリックスメタロプロテアーゼ / 遺伝子変異 / 国際交流 / 生物学 / 国際学術集会 / 一酸化窒素(NO) / NOS阻害剤 / NO合成酵素 / 分子機構 / 体内動態 / レセプター / 生理活性物質 / 医薬品開発 / 薬物治療 / 遺伝子治療 / 血管新生 / 化学療法 / 癌転移 / EBウイルス / フラクタル / 高度不飽和脂肪酸 / コメ / 炎症性疾患 / 低侵襲治療 / 難治性癌 / 腫瘍集積性 / 肝臓集積性 / 核酸医薬 / microRNA / DDS / 癌幹細胞 / 酵素補充療法 / カンジダ死菌による肉芽腫モデル / カンジダ死菌による肺肉芽腫症 / D-amino acid / PEG-DAO / カンジダ死菌による肺炎実験 / D型アミノ酸 / カンジダ死菌誘発性肺炎 / CGDマウス / PEG-DAO酵素補充療法 / THIOL MODIFICATION / α_1-PROTEASE INHIBITOR / S-NITROSULFOXYDE / MATRIX METALLOPROTEINASE / GLUTATHIONE / NITRIC OXIDE / NITROSOTHIOLS / セルロプラスミン / α1-プロテアーゼインヒビター / matrix metalloproteinase / グルタチオン付加反応 / SH基修飾 / α1プロテアーゼインヒビター / S-ニトロソスルフォキシド / マトリクスメタロプロテアーゼ / ECD / 8-NITROGUANOSINE / 3-NITROTYROSINE / NO-RELATED COMPOUNDS / ニトロチロシン / ニトログアニン / ニトロトリプトファン / 電気化学検出法 / ニトロ化ストレス / 3-ニトロチロシン / NO関連物質 / 8-MTROGUANOSINE / MOLECULAR EVOLUTION / VIRAL MUTATION / MUTAGENESIS / GENETIC MUTATION / OXIDATIVE STRESS / 塩基損傷 / 分化進化 / 抗8-nitroguanine抗体 / 8-nitroguanine / 抗8-ニトログアノシン抗体 / 分子進化 / ウイルス変異 / 変異原性 / 酸化ストレス / cytochrome b562 / recombinant human serum albumin / human serum albumin / S-nitrosylation / α_1-acid glycoprotein / pyridoxalated hemoglobin polyoxyethylene conjugate / 血漿由来HSA / 組換え型HSA / 血流阻害抑制作用 / αー1酸性糖タンパク / ポリオキシエチレン・重合ヘモグロビン(PHP) / 人口酸素運搬体 / シトクロムb562変異体 / ミオグロビン変異体 / 変異アルブミン / 炎症 / 白血球走化性抑制作用 / 微細循環改善作用 / 細隙通過促進作用 / α-1酸性糖タンパク / 配位子結合性 / ミオグロビン / Cys残基 / 酸化アルブミン / シトクロムb562 / 組換え型アルブミン / ヒト血清アルブミン / S-ニトロソ化 / α_1酸性糖蛋白 / ピリドキシル化ポリオキシエチレンヘモグロビン重合体 / viral evolution / viral mutation / oxidative stress / NO消去剤 / 病原因子 / herpes simplex virus / influenza virus / virus infection / nitric oxide / 酸化窒素 / ヘルペスウイルス / インフルエンザウイルス / tumor suppressor gene / oncogene / human cancer / cancer metastasis / cell-cell interaction / signal transduction / apoptosis / cell differentiation / cell growth / 2国間共同研究 / ヒトゲノム / DNA修復 / がん細胞 / がん抑制遺伝子 / がん遺伝子 / ヒトがん / がん転移 / 細胞間相互作用 / シグナル伝達 / 細胞死 / 細胞分化 / 細胞増殖 / Pulmonary fibrosis / Viral pneumonia / Nitric oxide / Free radicals / ラジカル消去剤 / ウイルス性肺炎 / 間質性肺炎 / フラクタル次元 / 粉末状エマルション / 押出し成型法 / 高分子ハイブリッド制癌剤 / 酵素修飾米 / コメプロラミン / 酵母イソ-ノ-チトクロムC / キニン濃度 / 薬理動態 / 肝癌、血管透過性 / 動注療法 / 癌性腹膜炎 / アンギオテンシン昇圧 / 2経路化学療法 / 改良癌化学療法 / ヘルパーTの活性化 / CTL活性化 / マクロファージの活性化 / BRM(biological response modifier) / SMANCS / スマンクス / 改良2経路化学療法 / Lipiodol / Smancs / 昇圧癌化学療法 / アンギオテンシン【II】 / 選択的癌化学療法 / 腫瘍組織の循環特性 / 抗腫瘍療法 / ターゲティング療法 / ポリマー結合型エンドスタチン / 血管新生抑制療法 / エンドスタチン / ポリマー結合ZnプロトポルフィリンIX / アポトーシス / 抗腫瘍効果 / ヘムオキシゲナーゼ阻害剤 / ZnプロトポルフィリンIX / 抗酸化酵素 / ヘムオキシゲナーゼ-1 / ポリマーコンジュゲート / 酸化酵素 / キサンチンオキシダーゼ / 血管透過性 / ヘムオキシゲナーゼ / 組織修復 / 組織破壊 / ウイルス分子進化 / キメラ抗体 / ミサイル療法 / マイクロスフェア- / NOS / 電子スピン共鳴法 / ウイルス感染 / チトクロムP-450 / NO-ヘム / グアニレートシクラーゼ / Drug Delivery System / アンチセンスDNA / モノクローナル抗体 / ターゲッティング / ヘテロサイクリックアミン / P450レダクターゼ / アルキルパーオキシラジカル / プロモーター / antioxidant / 発癌 / 高分子化制癌剤 / アンチセンス遺伝子 / 血管新生阻害剤 / 加圧食品 / バイオヤンサー / エイコサペンタエン酸 / ハイブリッド修飾 / アレルゲン除去米 / 抗ウィルス / 分子テーラリング / バイオセンサー / 抗ウイルス / 分子テ-ラリング / 機能性ペプチド / コメアレルゲン / 機能性蛋白質 / 機能性食品 / トリプシンインヒビタ- / アレルギ- / ラジカル消去活性 / パ-オキシドラジカル / transformation / 食品成分 / progression / promotion / initiation / 高分子制癌剤 / 肝癌塞栓化学療法 / 時間差投与 / アンギオテンシン II / チオ硫酸ソ-ダ / シスプラチン / トリプシンインヒビター / アレルギー / 時間差化学療法 / Sodium thiosulfate / アンギオテンシン-II / シスプラチナ / 昇圧2経路化学療法 Less

Development of innovative nucleic acid medicine using EPR enhancer iNaD
- Principal Investigator
  
  Yamamoto Hirofumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Osaka University
Treatment with Polyethylene Glycol-Conjugated Fungal d-Amino Acid Oxidase Reduces Lung Inflammation in a Mouse Model of Chronic Granulomatous Disease
- Principal Investigator
  
  Nunoi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Miyazaki
Macromolecular anticancer agent, PEGylated Zinc protoporphyrin (ZnP) targeting HSP32Principal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sojo University
New miceller agent for antioxidation therapy based on XO inhibition using AHPPPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sojo University
EPR効果に基づく活性酸素生成型高分子薬の固形癌ターゲティング療法Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Sojo University
ポリマー結合型エンドスタチンによる癌のターゲティング療法
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
新規水溶性ヘムオキシゲナーゼ阻害剤の合成とその抗腫瘍活性
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
フリーラジカルによるヘリコバクターピロリ遺伝子の変異促進作用に関する研究Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kumamoto University
慢性感染に伴うフリーラジカル産生と発がんPrincipal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
固型腫瘍の発育・進展における一酸化窒素・酸素ラジカルの役割についての研究
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
ポリマー結合酸化酵素による癌のターゲティング化学療法
- Principal Investigator
  
  澤智裕
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kumamoto University
Research on microbial mutation and evolution involving oxidative stress
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Research on the role of NO in microbial pathogenesisPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kumamoto University
Development of analysis for all biologically relevant derivatives of NO
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kumamoto University
Study on the mechanism of nitrosothiol formation in biological systems
- Principal Investigator
  
  MIYAMOTO Yoichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Showa University
  Kumamoto University
フリーラジカルによるマトリックス・メタロプロテアーゼの活性化
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
Free radical generation in chronic infection and its implication in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
Application of plasma proteins as blood substitutes
- Principal Investigator
  
  NISHI Katsuhide
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  General pharmacology
- Research Institution
  KUMAMOTO UNIVERSITY
生体内ラジカル生成による発癌と抗ラジカル物質によるがん抑制Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
感染と炎症におけるメタロプロテアーゼの活性制御Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kumamoto University
慢性ウイルス肝炎における肝癌の成因:フリーラジカルと一酸化窒素代謝物による感染性発癌機構Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
フリーラジカルによるウイルス遺伝子変異メカニズムの解明
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
メタロプロテアーゼの炎症および組織リモデリングにおける作用メカニズムPrincipal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
第5回「NOの生物学」国際学術集会の研究内容に関する企画
- Principal Investigator
  
  戸田昇
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Shiga University of Medical Science
Molecular Mechanisms of Redox-Regulation in Viral Pathogenesis
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Matrix metalloproteinase activation in bacterial pathogenesisPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kumamoto University
Therapeutic application of NO scavenger and NO donor for endotoxin shockPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Kumamoto University
腫瘍血管透過性亢進メディエーター制御による制癌剤の腫瘍選択的ターゲティングの増強Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
メタロプロテアーゼの炎症および組織リモデリングにおける作用メカニズムPrincipal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
第5回「NOの生物学」国際学術集会の研究内容に関する企画
- Principal Investigator
  
  戸田昇
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Shiga University of Medical Science
ドラッグデリバリーの空間的・時間的制御
- Principal Investigator
  
  橋田充
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Targeting Cancer Chemotherapy : For the Control of Metastatic Liver CancerPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Kumamoto University
ドラッグデリバリーシステムを利用した癌のターゲティング療法
- Principal Investigator
  
  高橋俊雄
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Prefectural University of Medicine
一酸化窒素合成酵素及びチトクロームP-450還元酵素の誘導による制癌剤感受性増強Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
Viral Pathogenesis and Regulation Mechanism of Free Radicals in Host Responses : Role of Nitric Oxide
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
機能性食品設計の技術基盤の展開
- Principal Investigator
  
  荒井綜一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
オキシラジカルによる発癌促進とラジカルスカベンジャーによる抑制-新しい立場から-
- Principal Investigator
  
  甲木孝人
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
ドラッグデリバリーシステムを利用した癌のターゲティング療法
- Principal Investigator
  
  高橋俊雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto Prefectural University of Medicine
一酸化窒素合成酵素を標的とした固型癌の診断と治療-とくにNOによる血管透過性亢進作用の制御に基づく-Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kumamoto University
ドラッグデリバリーの空間的・時間的制御
- Principal Investigator
  
  橋田満
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
生体系におけるNOの合成と反応及びその検出
- Principal Investigator
  
  北川禎三
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Okazaki National Research Institutes
ウイルス感染病態における一酸化窒素(NO)の役割についての研究
- Principal Investigator
  
  赤池孝章
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
Cooperation and information exchange with European countries.
- Principal Investigator
  
  KUROKI Toshio
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Showa University
  The University of Tokyo
Pathogenesis of Bacterial Proteases : Involvement of Bradykinin and Nitric Oxide Synthesis PathwayPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kumamoto University
ドラッグテリバリーシステムを利用した癌のターゲティング療法
- Principal Investigator
  
  高橋俊雄
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyoto Prefectural University of Medicine
癌と骨髄の脈管の特性に基づく高分子制癌剤の昇圧下投与による効果増強と副作用の軽減Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
Involvement of virus infection in the pathogenesis of pulmonary fibrosis
- Principal Investigator
  
  AKAIKE Takaaki
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
癌と骨髄の脈管学的特性の違いに基づく高分子制癌剤の効果増強と副作用の軽減Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
Molecular pathogenesis of influenza virus infection : involvement of free radicals and bradykininPrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Kumamoto University
腫瘍局所に対する至適な化学療法の確立に関する研究
- Principal Investigator
  
  秋吉毅
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
固型腫瘍における血管透過性亢進とキニン産生系の活性化Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
食品中の発癌抑制作用を有する活性酸素消去物質の検索と同定
- Principal Investigator
  
  KATSUKI Takato
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
食品構造の修飾と新機能の開発
- Principal Investigator
  
  荒井綜一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
腫瘍局所に対する至適な化学療法の確立に関する研究
- Principal Investigator
  
  馬場恒男
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
固型腫瘍における血管透過性亢進とキニン産生系の活性化Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
食品構造の修飾と新機能の開発
- Principal Investigator
  
  荒井綜一
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Preparation of Polymer-Conjugated Bilirubin Oxidase and Treatment of JaundicePrincipal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kumamoto University
腫瘍局所に対する至適な化学療法の確立に関する研究
- Principal Investigator
  
  馬場恒男
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kyushu University
固型腫瘍における血管透過性亢進とキニン産生系の活性化Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
食品構造の修飾と新機能の開発
- Principal Investigator
  
  荒井綜一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Preparation of Polymer Conjugated Bilirubin Oxidase and Development of Therapeatic Method for Jaundice.Principal Investigator
- Principal Investigator
  
  MAEDA Hiroshi
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Kumamoto University
制癌霊の高分子化と油性化による腫瘍親和性の増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
腫瘍組織の循環病態生理の解析とそれに基づく選択的癌化学療法の基礎的・臨床的研究
- Principal Investigator
  
  涌井昭
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tohoku University
制癌剤の高分子化と油性化による腫瘍親和性の増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
生体親和性を有する新しい合成ポリマー結合体によるCTLの誘導と癌の免疫療法
- Principal Investigator
  
  甲木孝人
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
制癌剤の高分子化と油性化による腫瘍親和性の増強に関する基礎的研究Principal Investigator
- Principal Investigator
  
  前田浩
- Project Period (FY)
  1985
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University

All 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] Recollections of 45 years in research : From protein chemistry to polymeric drugs to the EPR effect in cancer therapy In Rapidly Changing World2011
- Author(s)
  Hiroshi Maeda
- Publisher
  Nova Science Publishers, Inc.(in press)
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Liver tumor targeting In Drug Delivery in Oncology. From Basic Research to Cancer Therapy2011
- Author(s)
  K.Hochdorffer, G.DiStefano, L.Fiume, H.Maeda, F.Kratz
- Publisher
  Wiley-VCH Verlag GmbH & Co.KG, Weinhein, Germany(in press)
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Cancer Drug Delivery (ed.Kratz)(The EPR-effect in Relation to Tumor Targeting(2011
- Author(s)
  H.Maeda
- Publisher
  Wiley-VCH(in press)
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Nova Science Book Chapter(Recollections of 45 years in research : From protein chemistry to polymeric drugs to the EPR effect in cancer therapy)2011
- Author(s)
  H. Maeda
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-20590049
[Book] The EPR-effect in Relation to Tumor Targeting In Drug Delivery in Oncology. From Basic Research to Cancer Therapy2010
- Author(s)
  H.Maeda
- Publisher
  Wiley-VCH Verlag GmbH & Co.KG, Weinhein, Germany(in press)
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Recollections of 45 years in research : From protein chemistry to polymeric drugs to the EPR effect in cancer therapy2010
- Author(s)
  H.Maeda
- Total Pages
  30
- Publisher
  Nova Science
- Data Source
  KAKENHI-PROJECT-20015045
[Book] Recollections of 45 years in research: From protein chemistry to polymeric drugs to the EPR effect in cancer therapy2010
- Author(s)
  H. Maeda
- Publisher
  Nova Science(in press)
- Data Source
  KAKENHI-PROJECT-20015045
[Book] Pharm. Perspective of Cancers Therapeutics(eds. Y.Lu and R.I.Mahato, Tumor targeted macromolecular drug delivery based on the enhanced permeability and retention effect in solid tumor.)2009
- Author(s)
  T. Seki, J. Fang, H. Maeda
- Publisher
  AAPS Springer Press
- Data Source
  KAKENHI-PROJECT-20015045
[Book] Pharm.Perspective of Cancers Therapeutics (eds.Y.Lu and R.I.Mahato)(Tumor targeted macromolecular drug delivery based on the enhanced permeability and retention effect in solid tumor.)2009
- Author(s)
  T.Seki, J.Fang, H.Maeda
- Publisher
  AAPS Springer Press, New York
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Tumor targeted macromolecular drug delivery based on the enhanced permeability and retention effect in solid tumor. In Pharmaceutical Perspectives of Cancer Therapeutics (eds.Y.Lu and R.I.Mahato)2009
- Author(s)
  T.Seki, J.Fang, H.Maeda
- Total Pages
  27
- Publisher
  AAPS Springer Press, New York
- Data Source
  KAKENHI-PROJECT-20590049
[Book] Tumor targeted macromolecular drug delivery based on the enhanced permeability and retention effect in solid tumor.In Pharmaceutical Perspectives of Cancer Therapeutics(eds.Y.Lu, R.I.Mahato)2009
- Author(s)
  T.Seki, J.Fang, H.Maeda
- Total Pages
  27
- Publisher
  AAPS Springer Press, New York
- Data Source
  KAKENHI-PROJECT-20015045
[Book] 21世紀の健康を考える-活性酸素と野菜の力-2007
- Author(s)
  前田浩
- Total Pages
  202
- Publisher
  幸書房(株)
- Data Source
  KAKENHI-PROJECT-17016076
[Book] Delivery of Protein and Peptide Drugs in Cancer (V. Torchilin)2006
- Author(s)
  K.Greish, A.K.Iyer, J.Fang, M.Kawasuji, H.Maeda
- Publisher
  Imperial College Press, London
- Data Source
  KAKENHI-PROJECT-17016076
[Book] Factors and mechanism of "EPR" effect and clinical outlook of SMANCS. Cancer Chemoprevention and Drug Therapy of the New Millennium (eds.R.Han, Y.Sun)2005
- Author(s)
  H.Maeda, J.Fang, T.Sawa
- Total Pages
  15
- Publisher
  People's Military Medical Press, Beijing
- Data Source
  KAKENHI-PROJECT-17016076
[Book] Use of lipiodol as carrier in cancer target chemotherapy. Cancer Chemoprevention and Drug Therapy of the New Millennium (eds.R.Han and Y.Sun)2005
- Author(s)
  H.Maeda, J.Fang, T.Sawa
- Total Pages
  14
- Publisher
  People's Military Medical Press, Beijing
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents ; Unique intracellular disintegration of SMA micelles2011
- Author(s)
  H.Nakamura, J.Fang, B.Gahininath, K.Tsukigawa, H.Maeda
- Journal Title
  
  J.Controlled Release
  
  Volume: (accepted)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] History and impact of EPR effect for the nanomedicine drug developments in cancer chemotherapy2011
- Author(s)
  H.Maeda, Y.Matsumura
- Journal Title
  
  Adv.Drug Delivery Reviews (available online)
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] History and impact of EPR effect for the nanomedicine drug developments in cancer chemotherapy2011
- Author(s)
  H.Maeda, Y.Matsumura
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: (available online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] EPR effect : the unique characteristics of tumor blood vessels for drug delivery, factors involved, its limitation and augmentation2011
- Author(s)
  J.Fang, H.Nakamura, H.Maeda
- Journal Title
  
  Advanced Drug Delivery Reviews
  
  Volume: (available online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Intracellular uptake and behavior of two types zinc protoporphyrin (ZnPP) micelles, SMA-ZnPP and PEG-ZnPP as anticancer agents ; Unique intracellular disintegration of SMA micelles2011
- Author(s)
  H.Nakamura, J.Fang, B.Gahininath, K.Tsukigawa, H.Maeda
- Journal Title
  
  J.Controlled Release (accepted)
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Synthesis and evaluation of poly(styrene-co-maleic acid) micellar nanocarriers for the delivery of tanespimycin2011
- Author(s)
  N.Larson, K.Greish, H.Bauer, H.Maeda, H.Ghandehari
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: (in preparation)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: Analogy between angina pectoris and solid tumors and enhancement of the EPR effect2010
- Author(s)
  H. Maeda
- Journal Title
  
  J. Cont. Release 142
  
  Pages: 296-298
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Tumor-selective delivery of macromolecular drugs via the EPR effect: Background and future prospects2010
- Author(s)
  H. Maeda
- Journal Title
  
  Bioconj. Chem. 21
  
  Pages: 797-802
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] EPR effect : the unique characteristics of tumor blood vessels for drug delivery, factors involved, its limitation and augmentation2010
- Author(s)
  J.Fang, H.Nakamura, H.Maeda
- Journal Title
  
  Adv.Drug Delivery Reviews (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] In vitro and in vivo evaluation of tumor targeting SMA-pirarubicin micelles: Survival improvement and inhibition of liver metastases.2010
- Author(s)
  J. Daruwalla,, et al, C. Christophi, H. Maeda(7/7番目)
- Journal Title
  
  Cancer Sci.
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Tissue protective effect of xanthine oxidase inhibitor, polymer conjugate SMA-AHPP, on hepatic ischemia-reperfusion injury2010
- Author(s)
  J.Fang, T.Seki, H.Qin, G.Y.Bharate, A.K.Iyer, H.Maeda
- Journal Title
  
  Exp.Biol.Medicine 235
  
  Pages: 487-496
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues : Analogy between angina pectoris and solid tumors and enhancement of the EPR effect2010
- Author(s)
  Hiroshi Maeda
- Journal Title
  
  J.Control Release
  
  Volume: 142 Pages: 296-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Tissue protective effect of xanthine oxidase inhibitor, polymer conjugate SMA-AHPP, on hepatic ischemia-reperfusion injury2010
- Author(s)
  J.Fang, T.Seki, H.Qin, G.Y.Bharate, A.K.Iyer, H.Maeda
- Journal Title
  
  Experimental Biology and Medicine
  
  Volume: 235 Pages: 487-496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Tissue protective effect of xanthine oxidase inhibitor, polymer conjugate SMA-AHPP, on hepatic ischemia-reperfusion injury2010
- Author(s)
  J.Fang, T.Seki, H.Qin, G.Y.Bharate, A.K.Iyer, H.Maeda
- Journal Title
  
  Exp.Biol.and Medicine Available online(Available online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Tissue protective effect of xanthine oxidase inhibitor, polymer conjugate SMA-AHPP, on hepatic ischemia-reperfusion injury2010
- Author(s)
  J. Fang(1/6番目), T. Seki, et al, H. Maeda(6/6番目)
- Journal Title
  
  Exp. Biol. Med. 235
  
  Pages: 487-496
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues : Analogy between angina pectoris and solid tumors and enhancement of the EPR effect2010
- Author(s)
  H.Maeda
- Journal Title
  
  J.Cont.Release 142
  
  Pages: 296-298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Tumor-selective delivery of macromolecular drugs via the EPR effect : Background and future prospects2010
- Author(s)
  Hiroshi Maeda
- Journal Title
  
  Bioconjugate Chemistry
  
  Volume: 21 Pages: 797-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] EPR effect: the unique characteristics of tumor blood vessels for drug delivery, factors involved, its limitation and augmentation2010
- Author(s)
  J. Fang, H. Nakamura, H. Maeda
- Journal Title
  
  Adv. Drug Deliv. Rev. (in press)
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] History and impact of EPR effect for the nanomedicine drug developments in cancer chemotherapy2010
- Author(s)
  H.Maeda, Y.Matsumura
- Journal Title
  
  Adv.Drug Delivery Reviews (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Tumor-selective delivery of macromolecular drugs via the EPR effect : Background and future prospects2010
- Author(s)
  H.Maeda
- Journal Title
  
  Bioconj.Chem. (available online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Identification of Hsp32 as a novel target in CD34+/CD38+ and CD34+/CD38- leukemic progenitor cells in AML.2010
- Author(s)
  H. Herrmann, et al, H. Maeda(14/15番目), P. Valent
- Journal Title
  
  Cancer Res. (Submitted)
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] History and impact of EPR effect for the nanomedicine drug developments in cancer chemotherapy2010
- Author(s)
  H. Maeda, Y. Matsumura
- Journal Title
  
  Adv. Drug Deliv. Rev. (in press)
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Tissue protective effect of xanthine oxidase inhibitor, polymer conjuga to SMA-AHPP, on hepatic ischemia-reperfusion injury2010
- Author(s)
  J.Fang, T.Seki, H.Qin, G.Y.Bharate, A.K.Iyer, H.Maeda
- Journal Title
  
  Exp.Biol.Medicine (available online)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] History and impact of EPR effect for the nanomedicine drug developments in cancer chemotherapy2010
- Author(s)
  H.Maeda, Y.Matsumura
- Journal Title
  
  Advanced Drug Delivery Reviews (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Controlling oxidative stress: therapeutic and delivery strategies.2009
- Author(s)
  H. Maeda
- Journal Title
  
  Adv. Drug Delivery 61(Reviews)
  
  Pages: 285-286
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglycerin application2009
- Author(s)
  T. Seki J. Fang, H. Maeda
- Journal Title
  
  Cancer Science 100
  
  Pages: 2426-2430
- NAID
  10027198725
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Styrene maleic acid-pirarubicin disrupts tumor microcirculation and enhances the permeability of colorectal Liver Metastases2009
- Author(s)
  J. Daruwalla, et al, H. Maeda(6/7番目), C. Christophi
- Journal Title
  
  J. Vascu. Res. 46
  
  Pages: 218-228
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPR-effect2009
- Author(s)
  H. Maeda, 他
- Journal Title
  
  Eur. J. of Pharmaceutics and Biopharmaceutics 77
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Elevating blood pressure as a strategy to increase tumor targeted delivery of macromolecular drug SMANCS : Cases of advanced solid tumors2009
- Author(s)
  A.Nagamitsu, K.Greish, H.Maeda
- Journal Title
  
  Jpn.J.Clinical Oncol. 39
  
  Pages: 756-766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Controlling oxidative stress : therapeutic and delivery strategies.2009
- Author(s)
  H.Maeda
- Journal Title
  
  Adv.Drug Delivery Reviews 61
  
  Pages: 285-286
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] SMA-copolymer conjugate of AHPP : a polymeric inhibitor of xanthineoxidase with potential antihyper tensive effect2009
- Author(s)
  J.Fang, A.K.Iyer, H.Nakamura, T.Seki, K.Greish, H.Maeda
- Journal Title
  
  J.Cont.Release 135
  
  Pages: 211-217
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPR-effect.2009
- Author(s)
  H. Maeda, G.Y. Bharate, J. Daruwalla
- Journal Title
  
  Eur. J. Pharm. Biopharm. 71
  
  Pages: 409-419
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Elevating blood pressure as a strategy to increase tumor targeted delivery of macromolecular drug SMANCS: Cases of advanced solid tumors, Japan.2009
- Author(s)
  A. Nagamitsu, K. Greish, H. Maeda
- Journal Title
  
  J. Clinical Oncol. 39
  
  Pages: 756-766
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPR-effect.2009
- Author(s)
  H. Maeda, 他
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics 77
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPR-effect.2009
- Author(s)
  H.Maeda, G.Y.Bharate, J.Daruwalla
- Journal Title
  
  Eur.J.Pharm.Biopharm. 71
  
  Pages: 409-419
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Therapeutic strategies by modulating oxygen stress in cancer and inflammation2009
- Author(s)
  J.Fang T.Seki, H.Maeda
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 290-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Polymeric drugs and nanomedicines for efficient tumor targeted drug delivery based on EPR-effect2009
- Author(s)
  H.Maeda, G.Y.Bharate, J.Daruwalla
- Journal Title
  
  Eur.J.Pharm.Biopharm. 71
  
  Pages: 409-419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Controlling oxidative stress : therapeutic and delivery strategies2009
- Author(s)
  H.Maeda
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 285-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Controlling oxidative stress : therapeutic and delivery strategies2009
- Author(s)
  H. Maeda
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 285-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] SMA-copolymer conjugate of AHPP : a polymeric inhibitor of xanthine oxidase with potential antihypertensive effect2009
- Author(s)
  J.Fang, A.K.Iyer, H.Nakamura, T.Seki, K.Greish, H.Maeda
- Journal Title
  
  Journal of Controlled Release 135
  
  Pages: 211-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Enhanced delivery of macromolecular antitumor drugs to tumors by nitroglyicerin application2009
- Author(s)
  T.Seki J.Fang, H.Maeda
- Journal Title
  
  Cancer Science 100
  
  Pages: 2426-2430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Controlling oxidative stress : therapeutic and delivery strategies2009
- Author(s)
  H.Maeda
- Journal Title
  
  Advanced Drug Delivery Reviews 61
  
  Pages: 285-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Targeting of Hsp32 in solid tumors and leukemias: A novel approach to optimize anticancer therapy2009
- Author(s)
  K. Gleixner, et al, H. Maeda(16/18番目), P. Valent
- Journal Title
  
  Curr. Cancer Drug Targets 9
  
  Pages: 675-689
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Oxystress indusing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase.2008
- Author(s)
  J. Fang(1/8番目), H. Nakamura(3/8番目), et al, H. Maeda(8/8番目)
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 1135-1144
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Targeting of heat-shock protein32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apotosis.2008
- Author(s)
  E. Hadzijusufovic, et al, H. Maeda(13/15番目), P. Valent
- Journal Title
  
  Exp. Hematol. 36
  
  Pages: 1461-1470
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] 高分子薬剤のEPR効果による腫瘍デリバリーと癌治療2008
- Author(s)
  前田浩、関孝弘
- Journal Title
  
  血管医学 Vol.911月号
  
  Pages: 83-95
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] 4-vinyl-2,6dimethoxyphenol(Canolol)suppresses oxidative stress and gastric carcinogenesis in Helicobacter pylori-infected carcinogen-treated Mongolian gerbils.2008
- Author(s)
  X. Cao, T. Tsukamoto, T. Seki, H. tanaka, . Morimura, L. Cao, T. Mizoshita, H. Ban, T. Toyoda, H. Maeda and M. TAematsu.
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 1445-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Targeting of heat shock protein 32(Hsp32)/heme oxygenase-I (HO-1) in leukmic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib.2008
- Author(s)
  M. Mayerhofer, K. V. Gleixner, G. HOrmann, K. Sonnecek, K. j. Aichberger, R. G. Ott, K. Greish, H. Nakamura, S. Derdak, P. Samorapoomipichit, w. F. Pickl. V.sexl, H. Esterbauer, C.Sillaber. H. Maeda. P. Valent.
- Journal Title
  
  Blood 111
  
  Pages: 2200-2210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Targeting of heat shock protein 32 (Hsp32)/heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia: a novel approach to overcome resistance against imatinib.2008
- Author(s)
  M. Mayerhofer, et al, H. Maeda(15/16番目), P. Valent.
- Journal Title
  
  Blood 111
  
  Pages: 2200-2210
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] Oxystress indusing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated d-amino acid oxidase.2008
- Author(s)
  J. Fang, D. Deng, H. Nakamura, T. Akuta, H. Quin, A. Iyer, K. Greish, H. Maeda
- Journal Title
  
  Int. J. Cancer 122
  
  Pages: 1135-1144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Immunostimulation-mediated antitumor activity by preconditioning with rice-shochu distillation residue against implanted tumor in mice.2008
- Author(s)
  T. Seki, et al, H. Maeda(6/7番目), K. Kida
- Journal Title
  
  utrit. Cancer 60
  
  Pages: 776-783
- Data Source
  KAKENHI-PROJECT-20015045
[Journal Article] スマンクス・ダイナミックス療法仁よる各種進行形腫瘍に対する著明な抗腫瘍効果2007
- Author(s)
  永光彰典、犬塚貴雄、K・Greish、前田浩
- Journal Title
  
  DDS学会誌 22
  
  Pages: 475-486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] 経済効率主義vs トランスレーショナルリサーチ2007
- Author(s)
  前田浩
- Journal Title
  
  DDS学会誌 22
  
  Pages: 7-7
- NAID
  10018541629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Water-soluble polymer conjugates of ZnPP for photodynamic tumor therapy.2007
- Author(s)
  Regehly M, Greish K, Rahcan F, Maeda H, Bohm F, Foder B.
- Journal Title
  
  Bioconjug. Chem. 18
  
  Pages: 494-499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Targeting of heat shock protein 32 (Hsp32) / heme oxygenase-1 (HO-1) in leukemic cells in chronic myeloid leukemia : a novel approach to overcome resistance against imatinib2007
- Author(s)
  M.Mayerhofer, H.Nakamura, V.Sexl, H.Maeda, P.Valent, et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Polymeric micelles of zinc protorphyrin for tumor targeted delivery based on EPR effect and singlet oxygen generation.2007
- Author(s)
  A k lyer, k. Grish, T. SEki, S. Okazaki, J. Fang, K. TAkeshita and H. Maeda.
- Journal Title
  
  J Drug Targeting 15
  
  Pages: 496-506
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] High-loading nanosized micelles of copoly(styrene-maleic acid)-zinc protoporphyrin for targeted delivery of a potent heme oxygenase inhibitor.2007
- Author(s)
  A.K.Iyer, K.Greish, J.Fang, R.Murakami, H.Maeda
- Journal Title
  
  Biomaterials 28
  
  Pages: 1871-1881
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Identification of heat shock protein 32(Hsp32) as a novel survival factor and therapeutic target in neoplastic mast cells.2007
- Author(s)
  Kondo R, Gleixner KV, Mayerhofer M, Vales A, Gruze A, SAmorapoomichit P, Greish K, K rauth MT, Aichberger KJ, Pickl WF, Esterbauer H, Sillaber C, Maeda H, Valent P.
- Journal Title
  
  Blood 110
  
  Pages: 661-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Identification of heat shock protein 32 (Hsp32) as a novel KIT D816V-inducible survival factor and target in neoplastic mast cells2007
- Author(s)
  R.Kondo, H.Maeda, P.Valent, et al.
- Journal Title
  
  Blood (in press)
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] 日本のトランスレーショナルリサーチを活性化するために2007
- Author(s)
  前田浩
- Journal Title
  
  DDS学会誌 22
  
  Pages: 9-25
- NAID
  10018541630
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Water-soluble polymer conjugated of ZnPP for photodynamic tumour therapy2007
- Author(s)
  M.Regehly, K.Greish, F.Rancan, H.Maeda, F.Bohm, B.Roder
- Journal Title
  
  Bioconj. Chem. 18(2)
  
  Pages: 494-499
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Oxystress inducing antitumor therapeutics via tumor-targeted delivery of PEG-conjugated D-amino acid oxidase2007
- Author(s)
  J.Fang, D.Deng, H.Nakamura, T.Akuta, A.K.Iyer, K.Greish, H.Maeda
- Journal Title
  
  Int J Cancer (in press)
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Exploiting EPR-effect for tumor targeting : principle, mechanism and examples2006
- Author(s)
  A.K.Iyer, G.Khaled, J.Fang, H.Maeda
- Journal Title
  
  Drug Discovery Today 11
  
  Pages: 812-818
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Copoly (styrene-maleic-acid)-pirarubicin micelles : high tumor targeting efficacy with low toxicity2005
- Author(s)
  K.Greish, J.Fang, H.Maeda, et al.
- Journal Title
  
  Bioconj.Chem. 16
  
  Pages: 230-236
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Immunostimulation-mediated anti-tummor activity of bamboo(Sasa senanensis) leaf extracts obtained under 'vigorous' condition.
- Author(s)
  T. Seki, K. Kenji, H. Maeda
- Journal Title
  
  Evidence-based Complementary and Alternative Medicine (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016076
[Journal Article] Polymeric xanthine oxidase inhibitor with antiinflammatory and antihypertensive properties : PEG-conjugated micelle of 4-amino-6-hydroxypyrazolo [3,4-d] pyrimidine (AHPP)
- Author(s)
  G.Y.Bharate, J.Fang, H.Nakamura, K.Nakahara, T.Yamaguchi, S.Shinkai, H.Maeda
- Journal Title
  
  J.Drug Targeting (in preparation)
- Data Source
  KAKENHI-PROJECT-20590049
[Journal Article] Synthesis and evaluation of poly(styrene-co-maleic acid) micellar nanocarriers for the delivery of tanespimycin
- Author(s)
  N.Larson, K.Greish, H.Bauer, H.Maeda, H.Ghandehari
- Journal Title
  
  Bioconjugate Chemistry (in prepara-tion)
- Data Source
  KAKENHI-PROJECT-20590049
[Patent] Antitumor agents2009
- Inventor(s)
  H. Maeda
- Industrial Property Rights Holder
  H. Maeda
- Filing Date
  2009
- Overseas
- Data Source
  KAKENHI-PROJECT-20015045
[Patent] Antitumor agents2009
- Inventor(s)
  H. Maeda
- Industrial Property Rights Holder
  H. Maeda
- Acquisition Date
  2009-04-07
- Data Source
  KAKENHI-PROJECT-20015045
[Patent] 抗炎症剤2008
- Inventor(s)
  前田浩
- Industrial Property Rights Holder
  前田浩
- Industrial Property Number
  2008-176397
- Filing Date
  2008-07-07
- Data Source
  KAKENHI-PROJECT-20590049
[Patent] 抗炎症剤2008
- Inventor(s)
  前田浩、方軍、関孝弘、バラテガヒナシ
- Industrial Property Rights Holder
  前田浩、方軍、関孝弘、バラテガヒナシ
- Industrial Property Number
  2008-176397
- Filing Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Evaluation of (styrene-co-maleic acid) telomer micelles encapsulated-zinc protoporphyrin (SMA-ZnPP) : A stability study for three different types of SMA micelles2011
- Author(s)
  G.Y.Bharate, H.Nakamura, J.Fang, B.Klumperman, S.Shinkai, H.Maeda
- Organizer
  International Conference on Biomaterials Science 2011
- Place of Presentation
  つくば市(茨城県)
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Evaluation of (styrene-co-maleicacid) telomer micelles encapsulated-zinc protoporphyrin (SMA-ZnPP) : A stability study for three different types of SMA micelles2011
- Author(s)
  G.Y.Bharate, H.Nakamura, J.Fang, B.Klumperman, S.Shinkai, H.Maeda
- Organizer
  International Conference on Biomaterials Science 2011
- Place of Presentation
  茨城県(つくば市)
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Nanopa rticles of styrene-co-maleic acid (SMA) telomer containing anthracyclin and zinc-protoporphyrin (ZnPP) as new miceller anticancer agents, and SMA conjugate of AHPP, a xanthine oxidase inhibitor for oxystress diseases <Review>2011
- Author(s)
  H.Maeda, H.Nakamura, G.Y.Bharate, K.Tsukigawa, H.Qin, J.Fang
- Organizer
  International Conference on Biomaterials Science 2011
- Place of Presentation
  茨城県(つくば市)
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Nanoparticles of styrene-co-maleic acid (SMA) telomer containing anthracyclin and zinc-protoporphyrin (ZnPP) as new miceller anticancer agents, and SMA conjugate of AHPP, a xanthine oxidase inhibitor for oxystress diseases2011
- Author(s)
  H.Maeda, H.Nakamura, G.Y.Bharate, K.Tsukigawa, H.Qin, J.Fang
- Organizer
  International Conference on Biomaterials Science 2011
- Place of Presentation
  つくば市(茨城県)(Review)
- Year and Date
  2011-03-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] The enhanced permeability and retention effect in cancer and inflammation for more selective drug delivery : Past, present and future outlook2010
- Author(s)
  Hiroshi Maeda
- Organizer
  37th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  オレゴン州ポートランド(米国)
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] The EPR effect for tumor selective drug targeting : Its mechanism and future outlook2010
- Author(s)
  前田浩
- Organizer
  International Advanced Drug Delivery Symposium
- Place of Presentation
  Industrial Tech.Res.Inst., Taiwan
- Year and Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] The EPR effect for tumor selective drug targeting: Its mechanism and future outlook2010
- Author(s)
  H. Maeda
- Organizer
  nternational Advanced Drug Delivery Symposium
- Place of Presentation
  Industrial Tech. Res. Inst. (台湾)
- Year and Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Nitroglycerin facilitates tumor drug delivery via augmentation of vascular permeability involving NO generation in the hypoxic tumor tissue2010
- Author(s)
  H.Maeda, H.Nakamura, J.Fang
- Organizer
  The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
- Place of Presentation
  京都
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Limitations and augmentations of the EPR effect in solid tumor2010
- Author(s)
  H.Maeda, H.Nakamura, J.Fang
- Organizer
  8^<th> Int'l Symposium Polymer Therapeutic
- Place of Presentation
  バレンシア(スペイン)
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] The enhanced permeability and retention effect in cancer and inflammation for more selective drug delivery : Past, present and future outlook2010
- Author(s)
  前田浩
- Organizer
  37th Annual Meeting and Exposition of the Controlled Release Society
- Place of Presentation
  米国(ポートランド,OR)
- Year and Date
  2010-07-13
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Limitations and augmentations of the EPR effect in solid tumor2010
- Author(s)
  H.Maeda, H.Nakamura, J.Fang
- Place of Presentation
  スペイン(バレンシア)
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] ニトロ剤による腫瘍デリバリーの増強とその臨床成績、基礎2010
- Author(s)
  前田浩、方軍、中村秀明、J.Daruwalla
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] The EPR effect for tumor selective drug targeting : Its mechanism and future outlook2010
- Author(s)
  Hiroshi Maeda
- Organizer
  International Advanced Drug Delivery Symposium
- Place of Presentation
  台湾
- Year and Date
  2010-04-30
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Tumor selective targeting using macromolecular drugs based on EPR effect: Future solutions for solid tumor chemotherapy2009
- Author(s)
  H. Maeda
- Organizer
  3rd Roche Marco Polo Symposium on Drug Delivery
- Place of Presentation
  ソウル
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Tumor selective targeting using macromolecular drugs based on EPR effect : Future solutions for solid tumor chemotherapy2009
- Author(s)
  前田浩
- Organizer
  3rd Roche Marco Polo Symposium on Drug Delivery
- Place of Presentation
  ソウル(韓国)
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhancing the EPR-effect by nitroglycerin2009
- Author(s)
  前田浩, 等
- Organizer
  The 8th Int'l Symposium on Frontiers in Biomed. Polymers
- Place of Presentation
  静岡県三島市
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] ニトログリセリン軟膏塗布による癌局所への高分子制癌剤のEPR効果増強に基づくデリバリーと治療効果の増強2009
- Author(s)
  関孝弘、方軍、前田浩
- Organizer
  第9回日本NO学会
- Place of Presentation
  グランシップ(静岡県静岡市)
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] フェノール化合物キャノロールの炎症性腸疾患に対する抑制効果2009
- Author(s)
  前田浩
- Organizer
  がん予防学会2010
- Place of Presentation
  愛知県がんセンター
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Enhanced Permeability and Retention (EPR) Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  H. Maeda
- Organizer
  Seminar at Cedars-Sinal Medical Center
- Place of Presentation
  LA, USA
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] ニトログリセリン軟膏塗布による癌局所でのEPR効果増強に基づく制癌剤のデリバリーと治療効果の増強2009
- Author(s)
  前田浩, 等
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced Permeability and Retention (EPR) Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  H. Maeda
- Organizer
  USC-AAPS Moving Targets Symposium
- Place of Presentation
  LA, USA
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced Permeability and Retention (EPR) Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  前田浩
- Organizer
  USC-AAPS Moving Targets Symposium
- Place of Presentation
  The University of Southern California, LA, USA
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] 制癌剤開発における諸問題とDDSの役割2009
- Author(s)
  前田浩
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhancing the EPR-effect by nitroglycerin2009
- Author(s)
  前田浩等
- Organizer
  The 8^<th> Int'l Symposium on Frontiers in Biomed.Polymers
- Place of Presentation
  東レ総合研修センター(静岡県三島市)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Therapeutic potentials of SMA-copolymer conjugates of AHPP against hypertension via inhibiting xanthine oxidase2009
- Author(s)
  前田浩
- Organizer
  The 8th Int'l Symposium on Frontiers in Biomed.Polymer
- Place of Presentation
  東レ総合研修センター(静岡県三島市)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Tumor selective targeting using macromolecular drugs based on EPR effect: Future solutions for solid tumor chemotherapy2009
- Author(s)
  H. Maeda
- Organizer
  Int'l Symposium on Crystal Engineering & Drug Delivery System
- Place of Presentation
  天津(中国)
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced Permeability and Retention (EPR) Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  前田浩
- Organizer
  Seminar at Cedars-Sinai Medical Center
- Place of Presentation
  Cedars-Sinai Medical Center, California, LA, USA
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Current problems in cancer chemotherapy and new developments toward more cancer selective drug targeting based on EPR-effect2009
- Author(s)
  H. Maeda
- Organizer
  アジア薬科会議
- Place of Presentation
  福岡
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Remarkable augmentation of tumor delivery based on EPR-effect by topical applications of nitroglycerin2009
- Author(s)
  関孝弘、方軍、前田浩
- Organizer
  36th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Bella Center(デンマークコペンハーゲン)
- Year and Date
  2009-07-20
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] ニトログリセリン軟膏塗布による癌局所でのEPR効果増強に基づく制癌剤のデリバリーと治療効果の増強2009
- Author(s)
  前田浩等
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Current problems in cancer chemotherapy and new developments toward more cancer selective drug targeting based on EPR-effect2009
- Author(s)
  前田浩
- Organizer
  アジア薬科学議
- Place of Presentation
  九州大学医学部(福岡)
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Therapeutic potentials of SMA-copolymer conjugates of AHPP against hypertension via inhibiting xanthine oxidase2009
- Author(s)
  前田浩
- Organizer
  The 8th Int'l Symposium on Frontiers in Biomed.Polymer
- Place of Presentation
  静岡県三島市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] 成人T細胞白血病細胞に対するミセル化亜鉛プロトポルフィリンの増殖抑制作用(Growth inhibition of pegylated zinc protoporphyrin(PEG-ZnPP)on adult T-cell leukemia cells)2009
- Author(s)
  覃海波、方軍、中村秀明、前田浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] 制癌剤開発における諸問題とDDSの役割(特別講演)2009
- Author(s)
  前田浩
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京ドームホテル
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] 制癌剤開発における諸問題とDDSの役割(特別講演)2009
- Author(s)
  前田浩
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2009-07-04
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] 成人T細胞白血病細胞に対するミセル化亜鉛プロトポルフィリンの増殖抑制作用2009
- Author(s)
  覃海波、方軍、中村秀明、前田浩
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Remarkable augmentation of tumor delivery based on EPR-effect by topical applications of nitroglycerin2009
- Author(s)
  T. Seki, J. Fang, H. Maeda
- Organizer
  36th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  コペンハーゲン
- Year and Date
  2009-07-20
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] フェノール化合物キャノロールの炎症性腸疾患に対する抑制効果2009
- Author(s)
  前田浩等
- Organizer
  がん予防学会2010
- Place of Presentation
  愛知県がんセンター
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Cancer Preventive Effect of Kumaizasa Bamboo Leaf Extracts and Canolol from Rapeseed Oil2009
- Author(s)
  前田浩、関孝弘
- Organizer
  日伊国際シンポジウム
- Place of Presentation
  KKRホテル(東京)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Tumor selective targeting using macromolecular drugs based on EPR effect : Future solutions for solid tumor chemotherapy2009
- Author(s)
  前田浩
- Organizer
  Int'l Symposium on Crystal Engineering & Drug Delivery System
- Place of Presentation
  天津(中国)
- Year and Date
  2009-09-07
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] ニトログリセリン軟膏塗布による癌局所への高分子制癌剤のEPR効果増強に基づくデリバリーと治療効果の増強2009
- Author(s)
  関孝弘、方軍、前田浩
- Organizer
  第9回日本NO学会
- Place of Presentation
  静岡市
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced Permeability and Retention(EPR)Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  前田浩
- Organizer
  Seminar at Cedars-Sinal Medical Center
- Place of Presentation
  Cedars-Sinal Medical Center California, LA, USA
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced Permeability and Retention(EPR)Effect of Solid Tumor-The Universal Mechanism for Tumor Selective Delivery Using Macromolecular Therapeutics and Beyond2009
- Author(s)
  前田浩
- Organizer
  USC-AAPS Moving Targets Symposium
- Place of Presentation
  The University of Southern California, LA, USA
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced permeability and retention (EPR) effect of Solid tumor- The universal mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  City of Hope
- Place of Presentation
  LA, USA
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced permeability and retention (EPR) effect of Solid tumor-The universal mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  Seminar at Thomas Jefferson University
- Place of Presentation
  Thomas Jefferson Univ., Philadelphia, USA
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Tumor targeted delivery of PEG-conjugated D-amino acid oxidase for antitumor therapy via enzymatic generation of hydrogen peroxide2008
- Author(s)
  前田浩
- Organizer
  International Symposium on Polymer Therapeutics
- Place of Presentation
  Valencia, Spain
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced antitumor drug-delivery by topical applications of nitroglycerin on superficial tumors2008
- Author(s)
  前田浩, 他
- Organizer
  NO 5th International conference
- Place of Presentation
  Bregenz, Austlia
- Year and Date
  2008-08-26
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Highly immunopotentiating and cancer suppressing eifect of "Vigorous" extract of Kumaizasa Bamboo leaves2008
- Author(s)
  前田浩, 他
- Organizer
  Italian-Japanese Joint Symposium (FITMED 2008)
- Place of Presentation
  Salerno, Italy
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Enhanced permeability and retention (EPR) effect of Solid tumor- The universal mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  Thomas Jefferson Univ.
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced permeability and retention (EPR) effect of solid tumor - The universally mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  Seminar at Thomas Jefferson University
- Place of Presentation
  Thomas Jefferson Univ., Philadelphia, USA
- Year and Date
  2008-12-08
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] たん白化学/SMANCS/高分子制癌剤からEPR効果の発見まで2008
- Author(s)
  前田浩
- Organizer
  The 4th Sojo Frontier Seminar in Pharmaceutical Sciences
- Place of Presentation
  崇城大学
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced permeability and retention (EPR) effect of Solid tumor-The universal mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  Seminar at City of Hope
- Place of Presentation
  City of Hope, Los Angeles, USA
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Liver cancer in Egypt and an experience of collaboration in cancer treatment2008
- Author(s)
  前田浩
- Organizer
  Egypt-Japan Intemational symposium on science&technology
- Place of Presentation
  早稲田大学
- Year and Date
  2008-06-09
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] たん白化学/SMANCS/高分子制癌剤からEPR効果の発見まで : 46年の旅路2008
- Author(s)
  前田浩
- Organizer
  The 4th Sojo Frontier Seminar in Pharmaceutical Sciences
- Place of Presentation
  崇城大学
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] 崇城大学薬学部先端的研究の紹介2008
- Author(s)
  前田浩
- Organizer
  日本薬学会九州支部九州薬科学研究教育薬学研究フォーラム
- Place of Presentation
  日本薬学会「長井記念館」(東京)
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] Tumor targeted delivery of PEG*conjugated D-amino acid oxidase for antitumor therapy via enzymatic generation of hydrogen peroxide2008
- Author(s)
  前田浩
- Organizer
  International Symposium on Polymer Therapeutics
- Place of Presentation
  Valencia, Spain
- Year and Date
  2008-05-27
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] ニトログリセリンの局所塗布による表層がんへの高分子制がん剤のデリバリーと治療効果の増強2008
- Author(s)
  前田浩, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Enhanced permeability and retention (EPR) effect of solid tumor - The universally mechanism for tumor selective delivery using macromolecular therapeutics and beyond2008
- Author(s)
  前田浩
- Organizer
  Seminar at City of Hope
- Place of Presentation
  City of Hope, Los Angeles, USA
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20590049
[Presentation] ニトログリセリンの局所塗布による表層がんへの高分子制がん剤のデリバリーと治療効果の増強2008
- Author(s)
  前田浩, 他
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Highly immunopotentiating and cancer suppressing effect of"Vigorous"extract of Kumaizasa bamboo leaves2008
- Author(s)
  前田浩, 他
- Organizer
  Italian-Japanese Joint Symposium
- Place of Presentation
  Salerno, Italy
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20015045
[Presentation] Treatment of colorectal cancer liver metastases in CBA mice by augmentation by hyperbaric oxygen.2007
- Author(s)
  前田浩
- Organizer
  第34回CRS学会
- Place of Presentation
  カリフォルニア(米)
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] 制癌剤開発は何故進展が遅いか2007
- Author(s)
  前田浩
- Organizer
  第23回日本DDS学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] EPr-effects ,its mechanism, and further extension towards more tumour selective cancer therapy.2007
- Author(s)
  前田浩
- Organizer
  英国王立薬学会
- Place of Presentation
  マンチェスチター(US)
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] 高分子制癌剤の炎症と腫瘍集積性-EPR効果のメカニズムと人的増強2007
- Author(s)
  前田浩
- Organizer
  第22回長崎DDS研究会
- Place of Presentation
  長崎
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] Solid tumor treatment with SMANCS and other polymeric drugs by utilization of artificially enhanced vascular permeability of tumor.2007
- Author(s)
  前田浩
- Organizer
  韓国ハンミ社主催講演
- Place of Presentation
  韓国
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] 酸化ストレスと遺伝子変異-抗酸化剤の重要性2007
- Author(s)
  前田浩
- Organizer
  日本食品免疫学会
- Place of Presentation
  日本
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] Why we are losing the war on cancer; What is wrong in cancer drug development, and role of polymeric drug.2007
- Author(s)
  前田浩
- Organizer
  The 7th international symposium on frontiers in biomedical polymers.
- Place of Presentation
  ghent
- Data Source
  KAKENHI-PROJECT-17016076
[Presentation] Both infection and chemically induced cancer can be suppressed by a natural product, canolol from crude canola oil.2007
- Author(s)
  前田浩
- Organizer
  2nd Verona International Joint Meeting on Foods, Phytotherapeutc Compounds Health
- Place of Presentation
  Verona(Italy)
- Data Source
  KAKENHI-PROJECT-17016076

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Maeda Hiroshi 前田 浩

MAEDA Hiroshi 前田 浩

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Macromolecular anticancer agent, PEGylated Zinc protoporphyrin (ZnP) targeting HSP32Principal Investigator

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New miceller agent for antioxidation therapy based on XO inhibition using AHPPPrincipal Investigator

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EPR効果に基づく活性酸素生成型高分子薬の固形癌ターゲティング療法Principal Investigator

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フリーラジカルによるヘリコバクターピロリ遺伝子の変異促進作用に関する研究Principal Investigator

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慢性感染に伴うフリーラジカル産生と発がんPrincipal Investigator

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Research on the role of NO in microbial pathogenesisPrincipal Investigator

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Maeda Hiroshi 前田浩

MAEDA Hiroshi 前田浩