nomura yasuyuki 野村靖幸

… Alternative Names

NOMURA Yasuyuki 野村靖幸

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Researcher Number	00034041
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 客員教授
Affiliation (based on the past Project Information) *help	2013 – 2015: 久留米大学, 医学部, 教授 2007 – 2013: Yokohama College of Pharmacy, 薬学部, 教授 2006: Hokkaido University, Graduate School of Medicine, Invited Researcher, 大学院医学研究科, 招聘教員 2005: 北海道大学, 大学院・医学研究科, 招聘教員 1998 – 2004: 北海道大学, 大学院・薬学研究科, 教授 … More 1999 – 2000: 北海道大学, 薬学部, 教授 1998: 北海道大学, 大学院薬学研究科, 教授 1987 – 1997: Faculty of Pharm. Sci., Hokkaido Univ., 薬学部, 教授 1993: 北海道大学, 医学部, 教授 1990 – 1991: 北海道大学, 医学部, 教授 1986: 富山医薬大, 和漢薬研究所, 教授 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / 応用薬理学・医療系薬学 / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology Except Principal Investigator 内科学一般 / Biological pharmacy / Legal medicine / Cognitive science … More / Biological Sciences / Biological pharmacy / 医薬分子機能学 / Neurophysiology and muscle physiology Less
Keywords	Principal Investigator アポトーシス / 脳虚血 / ERAD / ニューロン / ユビキチンリガーゼ / 小胞体ストレス / 小胞体 / グリア / 神経細胞死 / GDNF … More / グリア細胞 / アルツハイマー病 / 神経変性疾患 / ストレス / APP / パーキンソン病 / NO / プロテインキナーゼC / 老化促進モデルマウス / アセチルコリン受容体 / 一酸化窒素合成酵素 / 神経伝達物質 / 老化促進マウス / 構造活性相関 / ケミカルシャペロン / PDI / ニューロン死 / NG108-15細胞 / イオンチャネル / GTP結合蛋白質 / 卵母細胞 / カスパーゼ / ischemia / 学習記憶障害 / senescence accelerated mouse (SAM) / brain ischemia / aging / アセチルコリン / DNA断片化 / 一酸化窒素 / NF-kB / JAK2 / 老化 / エンドトキシン / サイトカイン / Xenopus oocyte / ヒトTリンパ球 / cyclic AMP / 薬効評価法 / 予防治療薬 / セロトニン / 神経細胞 / Dorfin / 酸化ストレス / プロテアソーム / ユビキチン / caspase / 一酸化窒素(NO) / koningic acid / GAPDH / 海馬 / グルタミン酸受容体 / 百日咳毒素 / 共役機構 / 低分子量GTP結合蛋白質 / 受容体 / Fibroblast / Transformation / Oncogene / Chloride current / Serotonin receptor / Signal transduction / Gene transfer / Ras形質転換 / セロトニン応答電流 / 線維芽細胞 / 形質転換 / がん遺伝子 / クロライド電流 / セロトニン受容体 / 情報受容伝達機構 / 遺伝子移入 / C1 channel / Phorbol ester / Inositol Phosphate / Serotonin / GTP-binding protein / brain mRNA / Oocyte / Clチャネル / GTP結合蛋白 / Caチャネル / C1チャネル / ホルボールエステル / イノシトールリン酸 / 脳mRNA / transgenic mouse / Pael receptor (Pael-R) / parkin / neurodegenerative disease / nitrosylation / protein disulfide isomerase (PDI) / ER stress / nitric oxide (NO) / GMEB1 / 小胞体関連タンパク質分解 / 内在性抵抗因子 / パーキン / トランスジェニックマウス / Pael受容体(Pael-R) / バーキン / ニトロシル化 / 蛋白質ジスルフィドイソメラーゼ(PDI) / CREB / phosphatididylinositol 4-kinase / neurotrophic factor / learning deficiency / quantitative trait Loci analysis (QTL) / Senescence-accelerated mouse (SAM) / ハマボウフウ / ミエリン / インターロイキン-1β / Phosphatidylinositol 4-kinase / phosphatidylinositol 4-kinase / 神経栄養因子 / グリア細胞株由来 / 連鎖解析 / nitric oxide / chaperon / stress protein / apoptosis / glia / brain / HSP70 / アストログリア / p38MAPキナーゼ / 耐性 / 低酸素ストレス / neuronal death / depressive behavior / learning impairments / senescence accelerated mouse / アポートシス / ストレス刺激 / 虚血モデル / 促進老化マウス / グルタミンシンテターゼ / differential display法 / senescence accelerated mouse(SAM) / 加齢 / うつ病 / cytokine / glial cells / neuronal apoptosis / 核内転写因子 / カルシトニン / リンパ球 / 胸腺細胞 / サイトカン / SAM mouse / muscarinic antagonist / muscarinic ACh receptor / acetylcholine (ACh) / dementia / memory / learning / 空間認知機能改善作用 / [^3H]PDBu結合 / Moris's water maze / SAMP8系マウス / lithospermic acid B / 丹参 / 記憶・学習 / ラット / 痴呆 / 記憶 / 学習 / STAT1alpha / Herbimycin A / Interferon-gamma(IFN-gamma) / Endotoxin / Inducible NOS(iNOS) / Nitric oxide synthase(NOS) / 乳酸脱水素酵素漏出 / リン酸化 / 神経免疫相関 / stat1α / インターフェロンγ / ハービマイシンA / インターフェロン-γ / 誘導型NOS(iNOS) / 一酸化窒素合成酵素(NOS) / Neurochmistry / Pharmacology / Screening / Herbs / Therapeutics / Memory disturbance / Mouse / Aging / GABA受容体 / NMDA型グルタミン酸受容体 / M_1ムスカリン受容体 / 脳機能障害 / 神経伝達物質受容体 / 脳内機序 / 薬理学 / 神経化学 / 薬効評価 / 和漢薬 / 記憶障害 / Nitric acid dynthase / Glial cell / Neurite elongation / NG 108-15 cell / Interleukin 2 / Cytokine / Human lymphocyte / Neuroimmune interaction / インターロイキン2受容体 / 許容効果 / インターロイキン2 / TA-20 / NG 108-15細胞 / 神経突起伸展 / インターロイキン-2 / 神経-免疫協関 / Neuroprotective effect / Novel IL-2 receptor / Interleukin / Human T lymphocyte / Muscarinic receptor / Neurotransmitter / Neuro-immune interaction / プロテインキナ-ゼC / 細胞内遊離Ca^<2+> / トランスメンブラン機構 / ムスカリン性受容体 / T細胞 / 神経保護作用 / 新規ILー2受容体 / インタ-ロイキン / Jurkat細胞 / ムスカリン性アセチルコリン受容体 / 神経一免疫相関 / Second messengers / Senescent accelerated mice / Oriental medicines / Glutamate-receptor / alpha_2-receptor / Screening methods / Nootropic / Senile dementia / アデノシン受容体 / 二次メッセンジャ- / 生薬成分 / α_2受容体 / 老人痴呆 / 急性ストレス / 認知機能 / 遺伝子多型 / ゲノム・エピゲノム / DNAメチル化 / セロトニントランスポーター遺伝子多型 / DNA メチル化 / セロトニントランスポータ遺伝子多型 / 衝動性 / ノックアウトマウス / 質量分析 / HRD1 / RNF1９B / EDAD / エンドソーム / RNF19B / 膜輸送 / γ-セクレターゼ / アミロイドβ / Parkin / Aβ / 不溶化 / PKC / バイオインフォマティクス / シャペロン / 小胞 / ユビキリン / 低酸素 / アストロサイト / PI 4-K / 薬物作用 / 医療薬学 / 細胞・分子薬学 / 細胞内情報伝達 / 細胞間情報伝達 / 神経・免疫・内分泌相関 / 病態 / チトクロームC / ミトコンドリア / NOドナー / NO合成酵素 / Huntingtin / DNA fragmentation / adoptosis / neuron / mitric oxide / 神経突起進展因子 / カルモジュリン / S-ニトロソンステイン / ノルアドレナリン / シナプス伝達 / プロテインキナーゼA / SH-SY5Y細胞 / MPP^+ / Bcl-2 / 細胞死 / LPS / 細胞内機構 / 神経毒 / ツメガエル卵母細胞 / 抗うつ薬 / 神経突起形成 / トランスボーター / カルモジュリンキナ-ゼII / プロテインキナ-ゼC(Cキナ-ゼ) / Ca^<2+> / チャネル / NMDA受容体 / グルタミン酸 / NDPキナ-ゼ / 受容性 / トランスメンブランコントロ-ル / NDPキナーゼ / トランスメンブランコントロール … More Except Principal Investigator estrogen / tamoxifen / GTP結合蛋白質 / 受容体 / 蛋白架橋 / ATP合成酵素 / リアノジン結合蛋白質 / DHP結合蛋白質 / 筋小胞体 / IAP / cAMP / ICI182,780 / IGF-1 / Ca ion / 海馬 / c-fos mRNA / IGF-1 mRNA / nifedipine / エストロゲン / AP-1結合活性 / カイニン酸 / Gel shift assay / Insulin-like growth factor / Estrogen / Signal transduction / 情報伝達 / nicotine / 細胞核 / 細胞膜 / NDPキナーゼ / イオンチャネル / 細胞膜受容体 / 百日咳毒素 / 小胞体ストレス / ス-パ-オキシドジスムタ-ゼ / ムスカリン性アセチルコリン受容体 / トランスメンブランコントロ-ル / モデル動物 / 化学的神経回路網 / アルツハイマー病 / 低酸素環境 / Cytoplasmic factors / Endoplasmic reticulum / Lysosomes / Cell nucleus / Cell membrane / Organella / Metabolic regulation / Cellular responses / リソソーム / 代謝制御機構 / 細胞質因子 / 小胞体 / リソソ-ム / オルガネラ / 代謝制御 / 薬物応答 / Adenylate cyclase system / NIH3T3^<ras> / Phospholipase A_2 / Proliferation and differentiation of cells / GTP binding protein / 甲状腺細胞 / 3T3線維芽細胞 / アデニレートシクラーゼ系 / 増殖作用 / 免疫細胞系 / IAPの化学修飾 / セロトニン受容体 / ホスホリパーゼA_2 / アデニル酸シクラーゼ血小板トロンビン / 肝細胞 / c-myc / 大脳皮質膜アデニル酸シクラ-ゼ / 3T3NIH^<ras> / ホスホリパ-ゼA_2 / 情報伝達系 / 細胞の増殖と分化 / H19-7 cells / hippocampus / ICI182、780 / 不死化 / Caion / H19-7細胞 / CREB DNA binding activities / AP-1 DNA binding activities / Ca拮抗薬 / GAP43〜RNA / 大脳皮質 / IGF・1〜RNA / Caイオン / CREB結合活性 / c-fosmRNA / IGF-1mRNA / AP-1-DNA binding activity / Neuronal plasticity / Kainic acid / Neuronal growth factor / Hepatocyto growth factor / Estrogen受容体 / 神経細胞栄養因子 / LDH effluxmetry / 神経可塑性 / 神経栄養因子 / Hepatocyte growth factor / Phosphorylation / Effectors / Ion channels / Membrane receptors / Second messengers / GTP-binding proteins / リン酸化 / 効果器 / セカンドメッセンジャー / GTP結合タンパク質 / receptor kinase / betagamma-subunit of G protein / phospholipase / PI-3-kinase / wortmannin / protein tyrosine phosphorylation / cell differentiation / heterotrimeric G proteins / ビタミンD_3 / レチノイン酸 / ADPボシル化 / ホスホリパーゼD / ホスホリパーゼC / 細胞分化 / ワートマニン / NOPキナーゼ / 蛋白質チロシンリン酸化 / ワ-トマニン / PI-3-キナーゼ / 受容体キナーゼ / G蛋白質共役型受容体 / 3量体G蛋白質 / kinase IV / substance P / excitatory amino acids / GABA receptor / long-term potentiation / protooncogenes / long-term effects / カイネースIV / 268 / zif / interleukin-1β / AP-1 / GABAAα1サブユニットmRNA / c-fos / CABA^A受容体 / Myc / DBI mRNA / 長期増強 / NO 合成酵素 / dexamethasone / キナーゼIV / サブスタンスP / 興奮性アミノ酸 / GABA受容体 / 長期効果増強 / 原癌遺伝子 / 長期効果 / Standerdization / Terms in pharmaceutical sciences / Scientific terms / 標準化 / 薬学用語 / 学術用語 / G protein / gene regulation / transduction / cell nucleus / cytoplasm / cell membrane / receptors / drugs / organella constituents / m‐RNA構造 / 細胞膜タンパク質 / 膜結合性Gキナ-ゼ / ホルモン受容体 / 脂質輸送 / 細胞膜因子 / Cキナーゼ / Gタンパク質 / 遺伝子調節 / トランスダクション / 細胞質 / 薬物 / オルガネラ構成因子 / Neurochemistry / Brain aging / Receptor subtype / Intracellular signal transduction system / Neurotransmitter receptors / Mammalian brain / 神経ペプチド受容体 / 神経変性 / 遺伝子発現 / 細胞内カルシウムイオン濃度 / 神経化学 / 脳老化 / 受容体サブタイプ / 細胞内情報伝達機構 / 細胞内情報伝達系 / 神経伝達物質受容体 / 哺乳類脳 / アデニレートシクラーゼ / cDNAクローニング / 細胞内情報 / ドパミン / 罰 / 報酬 / 運動反応 / セロトニン神経系 / 報酬・罰 / tDCS / 遺伝子多型 / 反応競合 / 自己制御 / 前頭前野 / 個人差 / 遺伝子 / セロトニン / 運動反応制御 / 衝動性 / 神経細胞 / バイオインフォマティクス / Dorfin / Notch / アミロイドβ / APP / γ-セクレターゼ / ERAD / ユビキチンリガーゼ / 蛋白質 / 老化促進マウ / 酸化ストレス / 老化促進マウス / 老化 / 受容体リガンド / 医薬創製 / 民族伝統薬物 / 漢方薬 / 低酵素環境 / 老化促進モデルマウス / アルツハイマ-病モデル動物 / PGP9.5 / プロテインキナ-ゼC / GABA_A受容体 / ムスカリン性受容体 / グルタミナ-ゼ / 神経成長促進因子 / 神経組織の移植 / 視覚系の発達 / キンドリング / 小脳の長期抑圧 / 海馬の長期増強 / 神経系の可塑性 / 神経系の発生 / アドレナリン受容体 / アセチルコリン受容体 / アルツハイマ-病 / 細胞内代謝 / アセチルコリン / 伝達機構障害 / ムスカリン性アエチルコリン受容体 / トランスメンブランコントロール Less

Serotonin transporter gene-linked promotor-polymorphism and DNA methylation involved in personalized impulsivityPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kurume University
Involvement of novel ubiquitin ligases in the pathogenic mechanism of Alzheimer's disease and drug discovery for fundamental therapeutic agentPrincipal Investigator
- Principal Investigator
  
  Nomura Yasuyuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Kurume University
  Yokohama College of Pharmacy
Cognitive science on individual difference of impulsive behavior
- Principal Investigator
  
  NOMURA Michio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cognitive science
- Research Institution
  Kyoto University
新規ユビキチンリガーゼによる小胞体のタンパク質分解機構
- Principal Investigator
  
  金子雅幸
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba Institute of Science
The inhibitory mechanism of unfolded protein accumulation in the endoplasmic reticulum : Studies on anti-neurodegeneration drug discoveryPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama College of Pharmacy
Study on the mechanism underling development of neurodegenerative diseases with age-related dysfunction of the endoplasmic reticulum
- Principal Investigator
  
  TOMOBE Koji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Yokohama College of Pharmacy
小胞体蓄積タンパク質の分解促進/凝集抑制活性を有する抗脳変性疾患薬の創製Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Yokohama College of Pharmacy
The inhibitory mechanism of novel proteins induced in the endoplasmic reticulum and of drugs on neurodegenerative diseasesPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama College of Pharmacy
小胞体に蓄積する変性蛋白質の修復/分解系を用いた神経変性疾患防御機構Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Studies on the Regulatory Mechanism of Neuronal Death: Isolation of Novel Factors and Title of Preparation of Model of Neurodegenerative Disease.Principal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
小胞体での変性蛋白質分解に関与する分子の単離・同定と神経変性疾患防御機構Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
脳ニューロン・グリア細胞相関系のストレス応答機構に関する細胞分子生物学的研究Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Preparation of animal model with higher brain dysfunction : studies on evaluation methods of active chemicalsPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
A novel signal transduction pathway of estrogen in neuron
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  内科学一般
- Research Institution
  Hyogo University
脳のニューロンとグリア細胞の細胞膜受容体応答系への機能探索分子の作用と設計Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Hokkaido University
加齢病態・疾病発病に関わる神経・免疫・内分泌相関の細胞分子・医療薬学的研究Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Mechanisms of cellular and intracellular functions in brain-immune qnetwork.Principal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A).
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
脳グリア・ニューロン受容体シグナリング系応答の解析と機能探索分子の設計Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Steroid Hormones and Neuronal Survival-Molecular Biological Studies
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  内科学一般
- Research Institution
  Hyogo University
  Showa Women's University
Development of model animals and cells for neuronal diseasePrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
ニューロンの生死の制御機構に関する分子細胞生物学的研究Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
The molecular phamacological study of the interaction of neuro-immune systemPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
ニューロン死と防御に関する細胞分子生物学的研究Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
シナプス伝達の可塑性研究:制御因子の作用機序と新規因子の遺伝子の探索Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Estrogen and neuronal apoptosis -the molecular mechamism-
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of the Air
Establishment and estimation of pharmacological bioassay system for therapeutic drugs of aging in central nervous system.Principal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
神経毒のニューロン死機構:アポトーシスの関与と新規神経由来因子の防御作用Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
Molecular Pharmacological studies on the neuron/glia networkPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  HOKKAIDO UNIVERSITY
医薬創製理論構築のための基盤的研究-探索・設計・評価
- Principal Investigator
  
  広部雅昭
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokyo
The roles of heterotrimeric GTP-binding proteins in signal transduction
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo (Faculty of Pharmaceutical Sciences)
シナプスの形成と伝達を制御する細胞間、細胞内分子と作用機構Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
漢方薬を中心とした民族伝統薬物の先端技術による医薬学的解明と科学的確立
- Principal Investigator
  
  KIKUCHI Tohru
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
Long-term effects of intracerebral bioactive substances
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  内科学一般
- Research Institution
  THE UNIVERSITY OF THE AIR
Physiological Roles of Heterotrimeric G-proteins in Signal Transduction
- Principal Investigator
  
  UI Michio
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research (RIKEN)
  The University of Tokyo
The transmembrane mechanism on neuroimmune interactionPrincipal Investigator
- Principal Investigator
  
  YASUYUKI Nomura
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Studies on the Machanism of Memory Disturbances in Senescence-Accelerated Mouse and the Application to Screening of NootropicsPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Hokkaido University
アルツハイマ-病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
脳ニュ-ロン損傷と防御の機序に関する分子病態薬理学的研究Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
トランスメンブランコントロ-ルの機序
- Principal Investigator
  
  遠藤實
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Co-operative Responses of Organella Constituents to Drug stimulation
- Principal Investigator
  
  OHBA Yoshiki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kanazawa University
Investigation for the Standardization of Terms on Pharmaceutical Sciences
- Principal Investigator
  
  SUGA Tetsuya
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Institution
  Tokyo College of Pharmacy
トランスメンブランコントロ-ルにおけるGTP結合蛋白質の役割Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
トランスメンブランコントロ-ルの機序
- Principal Investigator
  
  遠藤實
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
アルツハイマ-病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
神経系の発生,可塑性に関する分子,細胞生物学の現状と展望
- Principal Investigator
  
  小幡邦彦
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Okazaki National Research Institutes
Cellular and molecular studies on the transmembrane mechanism of neuroimmuno-interactionPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
トランスメンブランコントロールにおけるGTP結合蛋白質の役割Principal Investigator
- Principal Investigator
  
  野村靖幸
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Hokkaido University
トランスメンブランコントロールの機序
- Principal Investigator
  
  遠藤實
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
アルツハイマー病における伝達機構障害
- Principal Investigator
  
  高木宏
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka City University
Neurotransmitter Receptor Mechanisms in Brain
- Principal Investigator
  
  KITO S
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  内科学一般
- Research Institution
  The University Of The Air
  Hiroshima University
Studies on screening methods for evaluation of novel nootropics and development of the drugsPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
トランスメンブランコントロールにおけるGTP結合蛋白質の役割
- Principal Investigator
  
  UI Michio
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
Analysis of Functional Cooperations between Organella in Responses to Medicines
- Principal Investigator
  
  ISHIBASHI Sadahiko.
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  Legal medicine
- Research Institution
  Hiroshima University
Molecular Pharmacological Studies on signal transduction cells reconstituted by gene transferPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Hokkaido University
Physiological roles of GTP binding protein associated with pertussis toxin (IAP) for the study of medicinal and diagnostic functions
- Principal Investigator
  
  TOKUMITSU Yukiko
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
Studies on the transmembrane signalling mechanism of neurotransmitter receptors and ion channels in Xenopus oocytes injected with rat brain mRNAPrincipal Investigator
- Principal Investigator
  
  NOMURA Yasuyuki
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Hokkaido University
  Toyama Medical and Pharmaceutical University

[Book] 四季の生薬2016
- Author(s)
  野村靖幸
- Total Pages
  439
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-24300135
[Book] Handbook of Cultural Neuroscience: Cultural Neuroscience and Health2015
- Author(s)
  Nomura M.
- Publisher
  Oxford University Press
- Data Source
  KAKENHI-PROJECT-25640041
[Book] 発達科学ハンドブック、第8巻脳の発達科学2015
- Author(s)
  野村理朗
- Publisher
  新曜社
- Data Source
  KAKENHI-PROJECT-25640041
[Book] 脳とこころ　唐沢かおり(編）｢社会心理学-心と社会をつなぐ知の統合-」2014
- Author(s)
  野村理朗
- Total Pages
  15
- Publisher
  北大路書房
- Data Source
  KAKENHI-PROJECT-25640041
[Book] 脳とこころ唐沢かおり(編)「新社会心理学 -心と社会をつなぐ知の統合-」2014
- Author(s)
  野村理朗
- Publisher
  北大路書房
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 青年期発達百科事典(第三巻「嗜癖」「ギャンブル」「アルコール摂取」「精神薬理学」「リスクテイキング行動」「喫煙」). 子安増生・二宮克美(監訳)丸善出版. (原書 : Brown, B. B. & Prinstein, M. J. (Ed.)2014
- Author(s)
  野村理朗(編集)
- Publisher
  Encyclopedia of Adolescence. Academic Press
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 情動　田中啓治・御子柴克彦（編）「脳科学辞典」2014
- Author(s)
  野村理朗
- Publisher
  脳科学辞典編集委員会
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 青年期発達百科事典（第三巻「嗜癖」「ギャンブル」「アルコール摂取」「精神薬理学」「リスクテイキング行動」「喫煙」）．子安増生・二宮克美（監訳）2014
- Author(s)
  野村理朗
- Publisher
  丸善出版
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 脳とこころ　唐沢かおり（編）「新社会心理学 -心と社会をつなぐ知の統合-」2014
- Author(s)
  野村理朗
- Total Pages
  15
- Publisher
  北大路書房
- Data Source
  KAKENHI-PROJECT-23500329
[Book] Genes, brain and culture through a 5-HTT lens. In Chiao, J, Shu-Chen, Rebecca, Bob (eds.), Handbook of Cultural Neuroscience: Cultural Neuroscience and Health.2014
- Author(s)
  Nomura, M.
- Publisher
  Oxford University Press
- Data Source
  KAKENHI-PROJECT-23500329
[Book] The Senescence-accelerated Mouse (SAM): Achievements and Future Directions2013
- Author(s)
  Hosoi T, Nomura J, Okuma Y, Nomura Y
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24300135
[Book] くすりと健康2013
- Author(s)
  野村靖幸
- Total Pages
  247
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-25640041
[Book] くすりと健康2013
- Author(s)
  野村靖幸
- Total Pages
  247
- Publisher
  薬事日報社
- Data Source
  KAKENHI-PROJECT-24300135
[Book] The Senescence-accelerated Mouse (SAM): Achievements and Future Directions2013
- Author(s)
  Tomobe K, Isobe M, Nomura Y
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24300135
[Book] Using NIRS to investigate social relationship in empathic process. "Infrared Spectroscopy - Life and Biomedical Sciences"2012
- Author(s)
  Ogawa, T., Nomura, M
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23500329
[Book] Using NIRS to investigate social relationship in empathic process.2012
- Author(s)
  Ogawa, T., Nomura, M
- Total Pages
  12
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-23500329
[Book] Psychopathy, Reward, and Punishment. "The Psychology of Reward"2012
- Author(s)
  Masui, K., Nomura, M., Ura, M.
- Total Pages
  32
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-23500329
[Book] Nova Science Publishers2012
- Author(s)
  Masui, K., Nomura, M., Ura, M.
- Publisher
  Psychopathy, Reward, and Punishment. "The Psychology of Reward"
- Data Source
  KAKENHI-PROJECT-23500329
[Book] Psychopathy, Reward, and Punishment. (Eds.) Michela Balconi. "The Psychology of Reward"2012
- Author(s)
  Masui, K., Nomura, M., Ura, M
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 衝動性廣中直行(編)「「心理学研究法」学習・動機・情動」2011
- Author(s)
  野村理朗
- Publisher
  誠心書房
- Data Source
  KAKENHI-PROJECT-23500329
[Book] ニューロイメージング子安増生・二宮克美(編)「キーワードコレクション・認知心理学」2011
- Author(s)
  野村理朗
- Publisher
  新曜社
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 「心理学研究法」学習・動機・情動2011
- Author(s)
  野村理朗
- Publisher
  誠心書房
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 衝動性子安増生・二宮克美(編)「キーワードコレクション・認知心理学」2011
- Author(s)
  野村理朗
- Publisher
  新曜社
- Data Source
  KAKENHI-PROJECT-23500329
[Book] 機能形態学(機能形態学総論)2008
- Author(s)
  野村靖幸
- Total Pages
  15
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-19300135
[Book] 機能形態学(機能形態学総論)2008
- Author(s)
  野村靖幸
- Total Pages
  15
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-20659013
[Book] 機能形態学総論2007
- Author(s)
  野村靖幸
- Publisher
  化学同人(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Book] 機能形態学総論2007
- Author(s)
  野村靖幸
- Publisher
  化学同人
- Data Source
  KAKENHI-PROJECT-15109002
[Book] Biochemical changes in the brain of the senescence-accelerated mouse (SAM)P8 and P10 in "The Senescence-Accelerated Mouse (SAM) An Animal model of Senescence(Ed. by Nomura Y, Takeda T, Okuma Y)2004
- Author(s)
  Nomura Y et al.
- Total Pages
  448
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] Involvement of serotonin transporter gene polymorphism (5-HTT) in impulsive behavior in the Japanese population2015
- Author(s)
  Nomura M., Kaneko M., Okuma Y., Nomura J., Kusumi I., Koyama T. and Nomura Y.
- Journal Title
  
  PLos One
  
  Volume: 10
- NAID
  120005745671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640041
[Journal Article] Modulation of empathy in the left ventrolateral prefrontal cortex facilitates altruistic behavior: An fNIRS study.2015
- Author(s)
  Himichi, T., & Nomura, M.
- Journal Title
  
  Journal of Integrative Neuroscience
  
  Volume: in press Issue: 02 Pages: 1-16
- DOI
  10.1142/s0219635215500120
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J05732, KAKENHI-PROJECT-25640041
[Journal Article] Negative emotions impacts lateral prefrontal cortex activation during Theory of Mind : An fNIRS study2015
- Author(s)
  Himichi T., Fujita H. and Nomura M.
- Journal Title
  
  Social Neuroscience
  
  Volume: なし Pages: 1-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640041
[Journal Article] Association of a nicotinic receptor gene polymorphism with spontaneous eyeblink rates.2015
- Author(s)
  Nakano, T., Kuriyama, C., Himichi, T., & Nomura, M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 8658-8658
- DOI
  10.1038/srep08658
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J05732, KAKENHI-PUBLICLY-25119504, KAKENHI-PROJECT-25560429, KAKENHI-PROJECT-25640041, KAKENHI-PROJECT-25700014
[Journal Article] Evaluation of synthetic naphthalene derivatives as novel chemical chaperones that mimic 4-phenylbutyric acid2015
- Author(s)
  Mimori, S., Koshikawa, Y., Mashima, Y., Mitsunaga, K., Kawada, K., Kaneko, M., Okuma, Y., Nomura, Y., Murakami, Y., Kanzaki, T., Hamana, H.
- Journal Title
  
  Bioorganic and Medicinal Chemistry Letters
  
  Volume: 25 Pages: 811-814
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300135
[Journal Article] Possible involvement of endoplamic reticulum stress in the pathogenesis of Alzheimer's disease2015
- Author(s)
  Hosoi, T., Nomura, J., Ozawa, K., Nishi, A., Nomura, Y.
- Journal Title
  
  Endoplasmic Reticulum Stress in Diseases
  
  Volume: 2 Issue: 1 Pages: 107-116
- DOI
  10.1515/ersc-2015-0008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300135
[Journal Article] Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligaseimplicated in Alzheimer's disease2014
- Author(s)
  Saito R., Kaneko M., Kitamura Y., et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 9巻 Issue: 5 Pages: 94576-94576
- DOI
  10.1371/journal.pone.0094576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J09807, KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119, KAKENHI-PROJECT-24790085, KAKENHI-PROJECT-26460099
[Journal Article] Pharmacological Studies on Neurodegenerative Diseases Focusing on Refolding and Degradation of Unfolded Proteins in the Endoplasmic Reticulum2014
- Author(s)
  野村靖幸
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 134 Issue: 4 Pages: 537-543
- DOI
  10.1248/yakushi.13-00252
- NAID
  130003391203
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2014-04-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24300135
[Journal Article] Beautiful Faces Enhance Verbal Working Memory Performance: An NIRS Study.2014
- Author(s)
  Kajimura, S., Himichi, T., & Nomura, M.
- Journal Title
  
  Psychologia: An International Journal of Psychological Sciences.
  
  Volume: .
- NAID
  130003391457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Aberrant neuronal differentiation and inhibition of dendrite outgrowth resulting from endoplasmic reticulum stress.2014
- Author(s)
  Kawada K, Iekumo T, Saito R, Kaneko M, Mimori S, Nomura Y, Okuma Y
- Journal Title
  
  Journal of neuroscience research
  
  Volume: 0 Issue: 9 Pages: 0-0
- DOI
  10.1002/jnr.23389
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119, KAKENHI-PROJECT-24790085, KAKENHI-PROJECT-26460099
[Journal Article] 日米で食薬区分の異なるメラトニンのインターネットを介した個人輸入における安全性情報の比較2014
- Author(s)
  大塚邦子、野村靖幸、内田直樹、安原一、小林真一
- Journal Title
  
  社会薬学
  
  Volume: 印刷中
- NAID
  130005092170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25640041
[Journal Article] Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease2014
- Author(s)
  Saito R., Kaneko M., Kitamura Y.,Takata K., Kawada K., Okuma Y. and Nomura Y.
- Journal Title
  
  PLos One
  
  Volume: 9
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300135
[Journal Article] Inhibition of inducible nitric oxide synthase and interleukin-1β expression by tunicamycin in cultured glial cells exposed to lipopolysaccharide2014
- Author(s)
  Noguchi J., Takakuwa M., Honda M., Okuma Y., Nomura Y. and Ozawa K.
- Journal Title
  
  Brain Research
  
  Volume: 1558 Pages: 11-17
- DOI
  10.1016/j.brainres.2014.02.035
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119, KAKENHI-PROJECT-25460101
[Journal Article] Non-conscious neural regulation against mortality concerns.2013
- Author(s)
  Yanagisawa, K., Kashima. E. S., Moriya. H., Masui, K., Furutani, K., Nomura. M., Yoshida, H., & Ura, M.
- Journal Title
  
  Neuroscience Letters
  
  Volume: 552 Pages: 35-39
- DOI
  10.1016/j.neulet.2013.07.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02398, KAKENHI-PROJECT-13J07480, KAKENHI-PROJECT-23330196, KAKENHI-PROJECT-23500329, KAKENHI-PROJECT-24240041
[Journal Article] Endoplasmic Reticulum Stress and Parkinson’s Disease: The Role of HRD1 in Averting Apoptosis in Neurodegenerative Disease2013
- Author(s)
  Omura T, Kaneko M, Okuma Y, Matsubara K, and Nomura Y
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: 2013 Pages: 239854-239854
- DOI
  10.1155/2013/239854
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-23790722, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119
[Journal Article] Discovery of Synthetic Methoxy-substituted 4-Phenylbutyric Acid Derivatives as Chemical Chaperones2013
- Author(s)
  Mimori S, Okuma Y, Kaneko M, Kawada K, Nomura Y, Murakami Y and Hamana H
- Journal Title
  
  Chem. Lett.
  
  Volume: 42 Issue: 9 Pages: 1051-1052
- DOI
  10.1246/cl.130419
- NAID
  10031194338
- ISSN
  0366-7022, 1348-0715
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135
[Journal Article] 4-Phenylbutyric acid protects against neuronal cell death by primarily acting as a chemical chaperone rather than histone deacetylase inhibitor.2013
- Author(s)
  Mimori S, Ohtaka H, Koshikawa Y, Kawada K, Kaneko M, Okuma Y, Nomura Y, Murakami Y, Hamana H
- Journal Title
  
  Bioorganic & medicinal chemistry letters
  
  Volume: 23 Issue: 21 Pages: 6015-6018
- DOI
  10.1016/j.bmcl.2013.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24590119
[Journal Article] COMT Val 158 Met influences the perception of other's pain.2012
- Author(s)
  Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M.
- Journal Title
  
  Psychology Research
  
  Volume: 2 Pages: 185-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Pharmacological/Underlying Interventions for Alzheimer's Disease2012
- Author(s)
  Nomura, Y.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 118 Pages: 317-318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] Possible Involvement of Ubiquitin Ligase HRD1 Insolubilization in Amyloid .BETA. Generation2012
- Author(s)
  Kaneko M、Saito R、Okuma Y、Nomura Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 2 Pages: 269-272
- DOI
  10.1248/bpb.35.269
- NAID
  130001872305
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142, KAKENHI-PROJECT-21590101, KAKENHI-PUBLICLY-22020032, KAKENHI-PROJECT-23790095
[Journal Article] Protective effects of 4-PBA(phenylbutyrate) derivatives on the neuronal cell death and endoplasmic reticulum stress2012
- Author(s)
  Mimori, S., Okuma, Y., Kaneko, M., Kawada, K., Hosoi, T., Ozawa, K., Nomura, Y. and Hamana, H.
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 35 Pages: 84-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] COMT Val 158 Met influences the perception of other's pain2012
- Author(s)
  Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
- Journal Title
  
  Psychology Research
  
  Volume: 2 Pages: 185-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Protective Effects of 4-Phenylbutyrate Derivatives on the Neuronal Cell Death and Endoplasmic Reticulum Stress2012
- Author(s)
  Mimori S、Okuma Y、Kaneko M、Kawada K、Hosoi T、Ozawa K、Nomura Y、Hamana H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 35 Issue: 1 Pages: 84-90
- DOI
  10.1248/bpb.35.84
- NAID
  130001872347
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142, KAKENHI-PROJECT-21590101, KAKENHI-PROJECT-22590100, KAKENHI-PROJECT-23790088, KAKENHI-PROJECT-23790095
[Journal Article] Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease:<BR>Possible Involvement of HRD1, a Novel Molecule Related to Endoplasmic Reticulum Stress, in Alzheimer’s Disease2012
- Author(s)
  Kaneko M、Okuma Y、Nomura Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Issue: 3 Pages: 325-330
- DOI
  10.1254/jphs.11R11FM
- NAID
  10030455441
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142, KAKENHI-PROJECT-21590101, KAKENHI-PUBLICLY-22020032, KAKENHI-PROJECT-23790095
[Journal Article] Possible involvement of HRD1, a novel molecule related to endoplasmic reticulum stress, in Alzheimer's disease2012
- Author(s)
  Kaneko, M., Okuma, Y. and Nomura, Y.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 118 Pages: 325-330
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] Activation of OASIS family, ER stress transducers, is dependent on its stabilization2012
- Author(s)
  Kondo S, Hino SI, Saito A, Kanemoto S, Kawasaki N, Asada R, Izumi S, Iwamoto H, Oki M, Miyagi H, Kaneko M, Nomura Y, Urano F and Imaizumi K
- Journal Title
  
  Cell Death Differ
  
  Volume: 19 Issue: 12 Pages: 1939-1949
- DOI
  10.1038/cdd.2012.77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790095, KAKENHI-PROJECT-24300135, KAKENHI-PROJECT-24659678, KAKENHI-PROJECT-24689058
[Journal Article] Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease:<BR>Preface: Pharmacological/Underlying Interventions for Alzheimer’s Disease2012
- Author(s)
  Nomura Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Issue: 3 Pages: 317-318
- DOI
  10.1254/jphs.11R12FM
- NAID
  10030455359
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142, KAKENHI-PROJECT-21590101, KAKENHI-PUBLICLY-22020032
[Journal Article] Expression of the Ubiquitin Ligase HRD1 in Neural Stem/Progenitor Cells of the Adult Mouse Brain2011
- Author(s)
  Kawada K、Kaneko M、Nomura Y、Mimori S、Hamana H、Ogita K、Murayama T、Fujino H、 Okuma Y
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 117 Issue: 3 Pages: 208-212
- DOI
  10.1254/jphs.11120SC
- NAID
  10030453464
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142, KAKENHI-PROJECT-21590101, KAKENHI-PROJECT-21590111, KAKENHI-PROJECT-21590120, KAKENHI-PUBLICLY-22020032, KAKENHI-PROJECT-23790095
[Journal Article] Expression of the ubiquitin ligase HRD1 in neural stem/progenitor cells of the adult mouse brain2011
- Author(s)
  Kawada, K., Kaneko, M., Nomura, Y., Mimori, S., Hamana, H., Ogita, K., Murayama, T., Fujino, H. and Okuma, Y.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 117 Pages: 208-212
- NAID
  10030453464
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011
- Author(s)
  Nomura, M.
- Journal Title
  
  Psychologia: An International Journal of Psychological Sciences
  
  Volume: 54 Pages: 241-151
- NAID
  130001896344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Age-related changes of Nrf2 and phosphorylated GSK-3b in a mouse model of accelerated aging (SAMP8).2011
- Author(s)
  Tomobe K., Shinozuka T., Kuroiwa M., Nomura Y.
- Journal Title
  
  Arch.Gerontol.Geriatr. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590095
[Journal Article] The effects of reward and punishment on response inhibition in non-clinical psychopathy2011
- Author(s)
  Masui, K., Nomura, M
- Journal Title
  
  Personality and Individual Differences
  
  Volume: 50 Pages: 69-73
- NAID
  120002753740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] The effects of the behavioral inhibition and activation systems on social inclusion and exclusion2011
- Author(s)
  Yanagisawa, K., Masui, K., Onoda, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
- Journal Title
  
  Journal of Experimental Social Psychology
  
  Volume: 47 Pages: 502-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011
- Author(s)
  Nomura, M
- Journal Title
  
  Psychologia : An International Journal of Psychological Sciences
  
  Volume: 54 Pages: 241-251
- NAID
  130001896344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Does higher general trust serve as a psychosocial buffer against social pain? : A NIRS study of social exclusion2011
- Author(s)
  Yanagisawa, K., Masui, K., Furutani, K., Nomura, M., Ura, M., Yoshida, H
- Journal Title
  
  Social Neuroscience
  
  Volume: 6 Pages: 377-387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Amount of altruistic punishment accounts for subsequent emotional gratification in participants with primary psychopathy2011
- Author(s)
  Masui, K., Iriguchi, S., Nomura, M., Ura, M
- Journal Title
  
  Personality and Individual Differences
  
  Volume: 51 Pages: 823-828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Perspective taking associated with social relationships : A NIRS study2010
- Author(s)
  Nomura, Y., Ogawa, T., Nomura, M
- Journal Title
  
  Neuroreport
  
  Volume: 21 Pages: 1100-1105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] 衝動性の基盤となる構成概念, 脳, 遺伝子多型について-Stop Signal Paradaigm の観点より-2010
- Author(s)
  増井啓太・野村理朗
- Journal Title
  
  感情心理学研究
  
  Volume: 18 Pages: 15-24
- Data Source
  KAKENHI-PROJECT-23500329
[Journal Article] Correlation between decrease in protein levels of ubiquitin ligase HRD1 and amyloid-beta production2010
- Author(s)
  Saito, R., Kaneko, M., Okuma, Y. and Nomura, Y.
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 113 Pages: 285-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-b generation.2010
- Author(s)
  Kaneko M., Koike H., Kitamura Y., Okuma Y., Nomura Y.
- Journal Title
  
  J.Neurosci. 30(11)
  
  Pages: 3924-3932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590095
[Journal Article] Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation2010
- Author(s)
  Kaneko, M., Koike, H., Saito, R., Kitamura, Y., Okuma, Y. and Nomura, Y.
- Journal Title
  
  J. Neurosci
  
  Volume: 30 Pages: 3924-3932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300142
[Journal Article] Correlation between decrease in protein levels of ubiquitin ligase HRD1 and amyloid-b production.2010
- Author(s)
  Saito R., Kaneko M., Okuma Y., Nomura Y.
- Journal Title
  
  J.Pharmacol.Sci. 113
  
  Pages: 285-288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590095
[Journal Article] Neurochemistry, neuropathology, and heredity in SAMP8: a mouse model of senescence2009
- Author(s)
  Tomobe K and Nomura Y.
- Journal Title
  
  Neurochem Res. 34
  
  Pages: 660-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Neurochemistry, Neuropathology, and Heredity in SAMP8 : A Mouse Model of Senescence.2009
- Author(s)
  Tomobe K., Nomura Y
- Journal Title
  
  Neurochem.Res. 34(4)
  
  Pages: 660-669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590095
[Journal Article] Immunohistochemical localization of a ubiquitin ligase HRD1 in murine brain.2008
- Author(s)
  Omura T., Kaneko M., Tabei N., Okuma Y., Nomura Y.
- Journal Title
  
  J.Neurosci.Res. 86
  
  Pages: 1577-1587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590095
[Journal Article] Vanadate inhibits endoplasmic reticulum stress responses2008
- Author(s)
  Hosoi, T., Saito, A., Kume, A., Okuma, Y., Nomura, Y. and Ozawa, K.
- Journal Title
  
  Eur J Pharmacol 594
  
  Pages: 44-48
- NAID
  120001092429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] GMEB1, a novel endogenous caspase inhibitor2008
- Author(s)
  Nakagawa, T., Tsuruma, K., Uehara, T. and Nomura, Y
- Journal Title
  
  prevents hypoxia- and oxidative stress-induced neuronal apoptosis, Neurosci Lett 438
  
  Pages: 34-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Immunohistochemical localization of a ubiquitin ligase HRD1 in murine brain2008
- Author(s)
  Omura, T., Kaneko, M., Tabei, N.,Okuma, Y. and Nomura, Y.
- Journal Title
  
  J. Neurosci. Res. 86
  
  Pages: 1577-1587
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Novel functions of ubiquitin ligase HRD1 with transmembrane and proline-rich domains2008
- Author(s)
  Omura, T., Kaneko, M., Onoguchi, M., Koizumi, S., Itami, M., Ueyama, M., Okuma, Y. and Nomura, Y.
- Journal Title
  
  J. Pharmacol. Sci. 106
  
  Pages: 512-519
- NAID
  10024319569
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] A different pathway in the endoplasmic reticulum stress-induced expression of human HRD1 and SEL1 genes2007
- Author(s)
  Kaneko, M., Yasui, S., Niinuma, Y., Arai, K., Omura, T., Okuma, Y. and Nomura, Y.
- Journal Title
  
  FEBS Lett. 581
  
  Pages: 5355-5360
- NAID
  120000951780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Impairment of CREB phosphorylation in the hippocampal CA1 region of the senescence-accelerated mouse (SAM) P82007
- Author(s)
  Tomobe, K., Okuma, Y. and Nomura, Y.
- Journal Title
  
  Brain Res. 1141
  
  Pages: 214-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300135
[Journal Article] Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior.2006
- Author(s)
  Nomura, M. et al.
- Journal Title
  
  Psychopharmacology 187
  
  Pages: 30-35
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] Involvement of a polymorphism in the 5-HT2A receptor gene in impulsive behavior.2006
- Author(s)
  Nomura, M., et al.
- Journal Title
  
  Psychopharmacology (Berl) 187
  
  Pages: 30-35
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] Aβ-induced TNF-α expression and acetylcholine action in mouse glial cells.2003
- Author(s)
  Nomura, J. et al.
- Journal Title
  
  Life Sci. 72
  
  Pages: 2117-2120
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] The presence and functions of mnscariric receptors in human T cells : The involvement in IL-2 and IL-2 receptor system.2003
- Author(s)
  Nomura, J. et al.
- Journal Title
  
  Life Sci. 72
  
  Pages: 2121-2126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Journal Article] Beautiful Faces Enhance Verbal Working Memory Performance : An NIRS Study
- Author(s)
  Kajimura, S., Himichi, T., & Nomura, M
- Journal Title
  
  Psychologia : An International Journal of Psychological Sciences
  
  Volume: (in press)
- NAID
  130003391457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23500329
[Patent] 小胞体ストレス関連疾患の予防・治療・診断標的分子としてのKF-12005
- Inventor(s)
  野村靖幸, 金子雅幸
- Industrial Property Rights Holder
  大塚製薬株式会社
- Filing Date
  2005-03-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Patent] APPおよびAβ産生抑制作用蛋白質HRD12005
- Inventor(s)
  野村靖幸, 金子雅幸
- Industrial Property Rights Holder
  大塚製薬株式会社
- Filing Date
  2005-12-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15109002
[Patent] APPおよびAβ産生抑制作用蛋白質HRD12004
- Inventor(s)
  野村靖幸, 金子雅幸
- Industrial Property Rights Holder
  大塚製薬(株)
- Industrial Property Number
  2004-150456
- Filing Date
  2004-05-20
- Data Source
  KAKENHI-PROJECT-15109002
[Patent] APPおよびAβ産生抑制作用蛋白質HRD12004
- Inventor(s)
  野村靖幸, 金子雅幸
- Industrial Property Rights Holder
  大塚製薬株式会社
- Filing Date
  2004-05-20
- Data Source
  KAKENHI-PROJECT-16659016
[Presentation] ４－フェニル酪酸およびその誘導体の小胞体ストレスに対する神経保護作用2016
- Author(s)
  大熊康修、三森盛亮、大高泰靖、川田浩一、金子雅幸、神埼哲人、野村靖幸
- Organizer
  第８９回日本薬理学会
- Place of Presentation
  (パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 脳の働き、認知症と薬の作用2015
- Author(s)
  野村靖幸
- Organizer
  日本杜仲研究会第１０回定期大会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2015-07-25
- Invited
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 自閉症スペクトラム症における小胞体ストレス付加と神経成熟異常2015
- Author(s)
  家雲高哲、川田浩一、三森盛亮、野村靖幸、大熊康修
- Organizer
  第４５回日本神経精神薬理学会・第３７回日本生物学的精神医学会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 小胞体ストレスによる神経成熟異常と神経発達障害2015
- Author(s)
  川田浩一、家雲高哲、金子雅幸、野村靖幸、大熊康修
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  兵庫医療大学、神戸市
- Year and Date
  2015-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Expression of ubiquitin ligases with transmembrane domain in the brain2015
- Author(s)
  金子雅幸、呉艶、高井知子、野村靖幸、今泉和則
- Organizer
  第５８回日本神経化学会大宮大会
- Place of Presentation
  大宮ソニックシティ（さいたま市）
- Year and Date
  2015-09-23
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] A novel therapeutic target against Alzheimer's disease: HRD1 as endolplasmic reticulum stress-related ubiquitin ligase2014
- Author(s)
  Nomura Y, Kaneko M, Okuma Y, Kitamura Y, Takata Y, Nishi A
- Organizer
  13th International Geneva/Springfield Symposium on Advances in Alzheimer Therapy
- Place of Presentation
  Geneve, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Envy decreases attention to sadness.2014
- Author(s)
  Fujita, H., Himichi, T., & Nomura, M.
- Organizer
  The 15th Annual Meeting of Society for Personality and Social Psychology.
- Place of Presentation
  San diego, USA
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] Effects of oxytocin receptor gene polymorphism and psychological stress on cognitive inferring of other’s mind.2014
- Author(s)
  2. Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M.
- Organizer
  The 15th Annual Meeting of Society for Personality and Social Psychology
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-25640041
[Presentation] 心的ストレスが他者の心的状態の推測へ及ぼす影響 ―fNIRSを用いた認知神経科学的検討―．2013
- Author(s)
  日道俊之・藤田弥世・野村理朗
- Organizer
  日本心理学会第77回大会
- Place of Presentation
  北海道医療大学
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 小胞体ストレスはユビキチンリガーゼHRD1を介して神経成熟を制御する2013
- Author(s)
  川田浩一, 金子雅幸, 斎藤僚, 野村靖幸, 大熊康修
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 妬み情動が注意バイアスに及ぼす影響―空間手がかり課題及びfNIRSを用いた認知神経科学的検討―．2013
- Author(s)
  藤田弥世・日道俊之・野村理朗
- Organizer
  日本心理学会第77回大会
- Place of Presentation
  北海道医療大学
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 日常的な失敗傾向の背景要因に関する検討.2013
- Author(s)
  梶村昇吾・野村理朗.
- Organizer
  日本心理学会第77回大会
- Place of Presentation
  北海道医療大学
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 酸化ストレスによるユビキチンリガーゼHRD1の不溶化がアルツハイマー病の病態形成に関与する可能性2013
- Author(s)
  斎藤僚, 金子雅幸, 川田浩一, 野村靖幸, 大熊康修
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Genes, brain and culture through a 5-HTT lens.2013
- Author(s)
  Nomura, M.
- Organizer
  nternational Cultural Neuroscience Consortium Conference.
- Place of Presentation
  Evanston, U.SA
- Invited
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] Genes, brain and culture through a 5-HTT lens2013
- Author(s)
  Nomura, M
- Organizer
  International Cultural Neuroscience Consortium Conference
- Place of Presentation
  Evanston, U.S
- Year and Date
  2013-05-11
- Invited
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] ユビキチンリガーゼDor丘nがAβ産生に関与する可能性2013
- Author(s)
  山森正嗣, 金子雅幸, 高野智喜, 川田浩一, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] ユビキチンリガーゼRNF19B発現抑制による、アミロイドβ産生抑制2012
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ツニカマイシン誘導性小胞体ストレスによる神経分化の障害2012
- Author(s)
  東野俊作、川田浩一、藤永直巳、金子雅幸、野村靖幸、大熊康修
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 成体マウスの神経幹細胞におけるHRD1の発現2012
- Author(s)
  佐藤俊介, 川田浩一, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体ストレスによる突起伸長抑制に対するユビキチンリガーゼHRD1の関与2012
- Author(s)
  川田浩一, 金子雅幸, 佐藤亜紗美, 野村靖幸, 大熊康修
- Organizer
  第35回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Attractive faces enhance cognitive performance2012
- Author(s)
  Kajimura, S., Himichi, T., Nomura, M
- Organizer
  43rd NIPS International Symposium
- Place of Presentation
  Okazaki, Japan
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] アルツハイマー病関連因子によるユビキチンリガーゼHRD1不溶化機構2012
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] Involvement of the 5-HT2A receptor gene polymorphism in trait anxiety, in activity of VLPFC and in impulsivity : a NIRS study2012
- Author(s)
  Kajimura, S., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
- Organizer
  28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] ツニカマイシン誘導性小胞体ストレスによる神経分化の障害2012
- Author(s)
  東野俊作, 川田浩一, 藤永直巳, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] Involvement of a polymorphism in the 5-HTT gene in impulsive response style in Japanese population2012
- Author(s)
  Nomura, M., Kaneko, M., Kusumi, I., Canli, T., Koyama, T., Nomura, Y
- Organizer
  28th World Congress of Collegium Internationale Neuro-Psychopharmacologium (CINP)
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 小胞体のタンパク質分解系ERADとアルツハイマー病2012
- Author(s)
  金子雅幸、大熊康修、野村靖幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼDorfinがCTFβのモノユビキチン化に影響してAβ産生に関与する可能性2012
- Author(s)
  高野智喜, 山森正嗣, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第126回薬理関東部会
- Place of Presentation
  北里大学(東京)
- Year and Date
  2012-07-15
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 小胞体のタンパク質分解系ERADとアルツハイマー病2012
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 成体マウスの神経幹細胞におけるHRD1の発現2012
- Author(s)
  佐藤俊介, 川田浩一, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] ユビキチンリガーゼRNF19B発現抑制による、アミロイドβ産生抑制2012
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] アルツハイマー病関連因子によるユビキチンリガーゼHRD1不溶化機構2012
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体のタンパク質分解系ERADとアルツハイマー病2012
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] 酸化ストレスによるアルツハイマー病関連ユビキチンリガーゼHRD1の不溶化2011
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがアルツハイマー病原因タンパク質アミロイドβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 酸化ストレスによるユビキチンリガーゼHRD1の不溶化と凝集体形成2011
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第125回薬理関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] 小胞体のタンパク質分解系ERADのアルツハイマー病への関与2011
- Author(s)
  金子雅幸、大熊康修、野村靖幸
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがアルツハイマー病原因タンパク質アミロイドβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] 酸化ストレスによるユビキチンリガーゼHRD1の不溶化とアルツハイマー病2011
- Author(s)
  金子雅幸, 齋藤僚, 大熊康修, 野村靖幸
- Organizer
  第38回日本脳科学会
- Place of Presentation
  那覇
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] 酸化ストレスによるアルツハイマー病関連ユビキチンリガーゼHRD1の不溶化2011
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体関連分解ERAD破綻によるアルツハイマー病発症機構2011
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] COMT Val 158 Met polymorphism modulates impulsivity-related human behavior2011
- Author(s)
  Nomura, M., Kondo, M. H., Kashino, M
- Organizer
  The International College of Neuropsychopharmacology, 1st IBRO MIDDLE EAST NEUROSCIENCE CONFERENCE
- Place of Presentation
  Al Ain, UAE
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 酸化ストレスによるユビキチンリガーゼHRD1の不溶化とアルツハイマー病2011
- Author(s)
  金子雅幸, 齋藤僚, 大熊康修, 野村靖幸
- Organizer
  第38回日本脳科学会
- Place of Presentation
  那覇
- Year and Date
  2011-10-09
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがアルツハイマー病原因タンパク質アミロイドβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-27
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがAβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第125回薬理関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] COMT Val158Met gene polymorphism influences the perception of others pain2011
- Author(s)
  Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M
- Organizer
  Clinical psychopharmacology and neuroscience, 2011, 9, P137. 2th Asian College of Neuropsychopharmacology
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがアルツハイマー病原因タンパク質アミロイドβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体のタンパク質分解系ERADのアルツハイマー病への関与2011
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Extraordinary progress of neuronal differentiation and maturation by tunicamycin-induced endoplasmic reticulum stress2011
- Author(s)
  川田浩一, 藤永直巳, 東野俊作, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  2011年度科研費特定領域研究「タンパク質の社会」班会議
- Place of Presentation
  日出町
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] アルツハイマー病発症におけるアミロイドβの産生増加に活性酸素種によるユビキチンリガーゼHRD1の不溶化が関与する可能性2011
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体のタンパク質分解系破綻によるアルツハイマー病発症機構2011
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] The interplay of genetic and environmental influences on prefrontal function and self-regulation of impulsivity2011
- Author(s)
  Nomura, M
- Organizer
  International symposium "Towards an empirical understanding of cultural, social and evolutionary perspectives in psychological science"
- Place of Presentation
  Lancaster. U. K
- Invited
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 小胞体のタンパク質分解系ERADのアルツハイマー病への関与2011
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀(招待講演)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] 酸化ストレスによるユビキチンリガーゼHRD1の不溶化と凝集体形成2011
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第125回薬理関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Possible involvement of ubiquitin ligase HRD1 insolubilization in the pathogenesis of Alzheimer's disease2011
- Author(s)
  Saito R, Kaneko M, Nomura Y, Okuma Y
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] Possible involvement of ubiquitin ligase HRD1 insolubilization in the pathogenesis of Alzheimer's disease2011
- Author(s)
  Saito, R., Kaneko, M., Nomura, Y. and Okuma, Y.
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体関連分解ERAD破綻によるアルツハイマー病発症機構2011
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Possible involvement of ubiquitin ligase HRD1 insolubilization in the pathogenesis of Alzheimer's disease2011
- Author(s)
  Saito R、Kaneko M、Nomura Y、Okuma Y
- Organizer
  Neuroscience 2011
- Place of Presentation
  Washington、DC
- Year and Date
  2011-11-14
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 神経幹細胞分化に及ぼす小胞体関連分解関連分子ユビキチンリガーゼHRD1の役割2011
- Author(s)
  川田浩一, 東野俊作, 佐藤亜紗美, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-03-22
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Extraordinary progress of neuronal differentiation and maturation by tunicamycin-induced endoplasmic reticulum stress2011
- Author(s)
  川田浩一, 藤永直巳, 東野俊作, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  2011年度科研費特定領域研究「タンパク質の社会」班会議
- Place of Presentation
  日出町
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがAβ産生に関与する可能性2011
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第125回薬理関東部会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PUBLICLY-22020032
[Presentation] Biological and psychological basis of impulsive behavior. The 32nd Naito Conference2011
- Author(s)
  Nomura, M
- Organizer
  Biological basis of mental functions and disorders
- Place of Presentation
  Yamanashi
- Year and Date
  2011-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] COMT Val158Met gene polymorphism influences the perception of others pain.2011
- Author(s)
  Himichi, T., Kaneko, M., Nomura, J., Okuma, Y., Nomura, Y., Nomura, M.
- Organizer
  2th Asian College of Neuropsychopharmacology
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 小胞体関連分解ERAD破綻によるアルツハイマー病発症機構2011
- Author(s)
  金子雅幸、大熊康修、野村靖幸
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] LPS誘導の骨量減少に対する低線量X線照射の影響2011
- Author(s)
  倉岡貴徳,小林芳子,出雲信夫,友部浩二,野村靖幸,加藤真介
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] 小胞体ストレスに関与するユビキチンリガーゼHRD1発現抑制による神経細胞分化への影響2010
- Author(s)
  川田浩一, 東野俊作, 佐藤亜紗美, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第12回応用薬理シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] The relationship between response disinhibition and rVLPFC deactivation in psychopathic participants : A near-infrared spectroscopy study2010
- Author(s)
  Masui, K., Nomura, M
- Organizer
  50th Annual Meeting of Society for Psychophysiological Research
- Place of Presentation
  Portland, USA
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] 骨量減少症モデルマウスに対する低線量X線の影響2010
- Author(s)
  小林芳子,出雲信夫,友部浩二,野村靖幸,加藤真介
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinがアルツハイマー病原因タンパク質アミロイドβ産生に関与する可能性2010
- Author(s)
  山森正嗣, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ヒト大脳皮質におけるユビキチンリガーゼHRD1の不溶化による減少とAβ産生量との相関2010
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Involvement of endoplasmic reticulum-associated degradation in amyloid-β generation2010
- Author(s)
  Kaneko, M., Saito, R., Yamamori, M., Okuma, Y. and Nomura, Y.
- Organizer
  ISPC-Nara
- Place of Presentation
  Nara
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼRNF19Bによるアミロイドβ前駆体タンパク質(APP)の分解の検討2010
- Author(s)
  小野口雅之, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Correlation between amyloid-β production and decrease in levels of ubiquitin ligase HRD1 due to its insolubilization2010
- Author(s)
  Kaneko, M., Saito, R., Okuma, Y. and Nomura, Y.
- Organizer
  Neuroscience 2010
- Place of Presentation
  San Diego
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼHRD1の不溶化による減少とアルツハイマー病発症の可能性2010
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第12回応用薬理シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体関連分解(ERAD)に関与するユビキチンリガーゼRNF19B発現抑制によるアミロイドβ(Aβ)の減少2010
- Author(s)
  金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第122回日本薬理学会関東部会
- Place of Presentation
  静岡
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼHRD1の不溶化による減少とアルツハイマー病原因タンパク質アミロイドβ産生との相関2010
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2010
- Place of Presentation
  京都
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Impulsivity-related human prefrontal brain activation during Go/No-go task is moderated by COMT Val 158 Met polymorphism : a fMRI study2010
- Author(s)
  Nomura, M., Kondo, M. H., Kashino, M
- Organizer
  The International College of Neuropsychopharmacology
- Place of Presentation
  Honkong, China
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] ユビキチンリガーゼHRD1発現抑制によるParkinの発現誘導2010
- Author(s)
  杉岡夏実, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Human HRD1 involved in the degradation of unfolded proteins has other functions than ubiquitin ligase activity in its transmembrane and proline-rich domains2009
- Author(s)
  Omura, T., Kaneko, M., Okuma, Y. and Nomura, Y.
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体関連分解(ERAD)に関与するユビキチンリガーゼRNF19Bによるアミロイド前駆タンパク質(APP)の分解についての検討2009
- Author(s)
  小野口雅之, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-β generation2009
- Author(s)
  Kaneko, M., Koike, H., Saito, R., Okuma, Y. and Nomura, Y.
- Organizer
  Neuroscience 2009
- Place of Presentation
  Chicago
- Year and Date
  2009-10-19
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] 小胞体のユビキチンリガーゼHRD1の減少はAPPの蓄積とAβの産生増加を引き起こす2009
- Author(s)
  金子雅幸, 小池洋, 齋藤僚, 野村靖幸, 大熊康修
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] アルツハイマー病患者脳におけるユビキチンリガーゼHRD1タンパク質の減少2009
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] 低線量X線連続照射のマウス骨量への影響2009
- Author(s)
  出雲信夫,小林芳子,友部浩二,西廣吉,野村靖幸,加藤真介
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] 大脳皮質におけるユビキチンリガーゼHRD1の減少がアルツハイマー病発症に関与する可能性2009
- Author(s)
  齋藤僚, 金子雅幸, 野村靖幸, 大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2009
- Place of Presentation
  東京
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] アルツハイマー病患者脳におけるユビキチンリガーゼHRD1タンパク質の減少とAβ産生機構2009
- Author(s)
  金子雅幸, 齋藤僚, 大熊康修, 野村靖幸
- Organizer
  第36回日本脳科学会
- Place of Presentation
  金沢
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-21300142
[Presentation] ユビキチンリガーゼHRD1の膜貫通領域およびproline-rich領域の機能解析2009
- Author(s)
  大村友博, 金子雅幸, 小野口雅之, 野村靖幸, 大熊康修
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] HRD1のタンパク質分解抑制は小胞体ストレスとアポトーシスを伴うアミロイド前駆体タンパク質の蓄積とAβの産生増加を引き起こす2008
- Author(s)
  金子雅幸, 小池洋, 大村友博, 大熊康修, 野村靖幸
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] HRD1の発現抑制によるAPP の分解阻害はAβ産生増加と小胞体ストレスを誘発する2008
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第35回日本脳科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] 小胞体関連分解ERADに関与するSEL1の脳内発現2008
- Author(s)
  金子雅幸, 井上慎也, 大村友博, 大熊康修, 野村靖幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] ユビキチンリガーゼHRD1のマウス脳内局在2008
- Author(s)
  大村友博,金子雅幸,田部井直樹,大熊康修,野村靖幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] SAMP8における学習記憶障害遺伝子の連鎖解析2008
- Author(s)
  友部浩二,磯部正治,近藤綾子,澤田昌伸,黒澤信幸,野村靖幸
- Organizer
  第23回老化促進モデルマウス(SAM)研究協議会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] ユビキチンリガーゼHRD1の発現抑制はAPPの蓄積と小胞体ストレスによるアポトーシスを誘導する2008
- Author(s)
  金子雅幸, 小池洋, 大村友博, 大熊康修, 野村靖幸
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] ユビキチンリガーゼHRD1のマウス脳内局在2008
- Author(s)
  大村友博, 金子雅幸, 田部井直樹, 大熊康修, 野村靖幸
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] ユビキチンリガーゼHRD1の発現抑制はAPPの蓄積と小胞体ストレスによるアポトーシスを誘導する2008
- Author(s)
  金子雅幸,小池洋,大村友博,大熊康修,野村靖幸
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590095
[Presentation] The brain distribution of a ubiquitin ligase HRD1 in mice2008
- Author(s)
  Okuma, Y., Omura, T., Kaneko, M. and Nomura, Y.
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] Suppression of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and b-amyloid generation with endoplasmic reticulum stress and apoptosis2008
- Author(s)
  Kaneko, M., Koike, H., Omura, T., Okuma, Y. and Nomura, Y.
- Organizer
  Neuroscience 2008
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] ユビキチンリガーゼHRD1の膜貫通領域およびproline-rich領域の機能解析2008
- Author(s)
  小野口雅之, 大村友博, 金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第119回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] 小胞体関連分解ERADに関与するHRD1はAPPによるアポトーシス抑制する2007
- Author(s)
  金子雅幸, 小池洋, 大村友博, 大熊康修, 野村靖幸
- Organizer
  Neuro2007(第50回日本神経化学会大会)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] 小胞体の変性タンパク質分解関連分子HRD1によるAPPの分解と神経細胞死抑制2007
- Author(s)
  金子雅幸, 大熊康修, 野村靖幸
- Organizer
  第34回日本脳科学会
- Place of Presentation
  出雲
- Data Source
  KAKENHI-PROJECT-19300135
[Presentation] Effect of 5HT2A receptor gene polymorphism on lateral prefrontal cortex activation during empathy
- Author(s)
  Himichi T., Kaneko M., Nomura J., Okuma Y., Nomura Y. and Nomura M.
- Organizer
  17th World Congress of Psychophysiology
- Place of Presentation
  International Conference Center Hiroshima, Hiroshima, Japan
- Year and Date
  2014-09-23 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25640041
[Presentation] The endoplasmic reticulum stress may contribute to the pathogenesis of the autism spectrum disorders
- Author(s)
  Kawada K., Iekumo T., Saito R., Mimori S., Nomura Y. and Okuma Y.
- Organizer
  Collegium Internationale Neuro-Psychopharmacologium 2014
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 小胞体ストレスによる神経突起の伸張抑制
- Author(s)
  川田浩一，家雲髙哲，齋藤　僚，金子雅幸，野村靖幸，大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2013
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] ユビキチンリガーゼDorfinがアミロイド前駆体タンパク質輸送を介したアミロイドβ産生に関与する可能性
- Author(s)
  金子雅幸，山森正嗣，保住功，野村靖幸，大熊康修
- Organizer
  Neuro2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] ユビキチンリガーゼDorfinとRNF19Bがアミロイド前駆体タンパク質輸送を介したアミロイドβ産生に関与する可能性
- Author(s)
  金子雅幸，山森正嗣，野口尚樹，齋藤僚，保住功，大熊康修，野村靖幸
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Relationship between racial essentialism disposition, emotion and genetics
- Author(s)
  Fujita H., Himichi T. and Nomura M.
- Organizer
  16th Annual Meeting of Society for Personality and Social Psychology
- Place of Presentation
  Long Beach, California, USA
- Year and Date
  2015-02-26 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-25640041
[Presentation] 小胞体関連分解構成因子SEL1Lの発現抑制による神経分化の抑制
- Author(s)
  齋藤僚，川田浩一，金子雅幸，野村靖幸，大熊康修
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2013
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] アミロイド前駆体タンパク質APP代謝とユビキチンリガーゼ
- Author(s)
  金子雅幸，大熊康修，野村靖幸
- Organizer
  生体機能と創薬シンポジウム2013
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 小胞体に局在するユビキチンリガーゼの発現分布
- Author(s)
  呉艶、今泉和則、野村靖幸、金子雅幸
- Organizer
  第８８回日本薬理学会
- Place of Presentation
  名古屋国際会議場、名古屋市
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] ユビキチンリガーゼHRD1の不溶化機構における酸化ストレスの影響
- Author(s)
  齋藤僚，金子雅幸，川田浩一，野村靖幸，大熊康修
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Involvement of the 5-HT2A receptor gene polymorphism in trait anxiety, in activity of VLPFC and in impulsivity: a NIRS study
- Author(s)
  Kajimura, S., Kaneko, M., Nomura, J., Canli, T., Koyama, T., Nomura, Y.
- Organizer
  Internationale Neuro-Psychopharmacologium (CINP)
- Place of Presentation
  Stockholm
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] Does the right inferior parietal lobule correlate with task-unrelated thoughts? : A transcranial direct current
- Author(s)
  Nomura M., Kadono Y. and Kajimura S.
- Organizer
  12th International Conference on Alzheimer's and Parkinson's Diseases
- Place of Presentation
  Nice, France
- Year and Date
  2015-03-18 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-25640041
[Presentation] 自閉症における小胞体ストレスの関与
- Author(s)
  川田浩一，家雲高哲，齋藤僚，金子雅幸，野村靖幸，大熊康修
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Studies of themechanism of action in protective effect against neuronal cell death of 4-phenylbutyrate and its derivatives for therapeutic agents of neurodegenerative disease
- Author(s)
  Mimori S., Ohtake H., Kawada K., Kaneko M., Nomura Y., Okuma Y., Murakami Y. and Hamana H.
- Organizer
  Collogium Internationale Neuro-Psychopharamcologium 2014
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-22 – 2014-06-26
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] Involvement of a polymorphism in the 5-HTT gene in impulsive response style in Japanese population
- Author(s)
  Nomura, M., Kaneko, M., Kusumi, I.,
- Organizer
  Internationale Neuro-Psychopharmacologium (CINP)
- Place of Presentation
  Stockholm
- Data Source
  KAKENHI-PROJECT-23500329
[Presentation] ユビキチンリガーゼRNF19BおよびDorfinの複合体形成の可能性
- Author(s)
  野口尚樹，金子雅幸，山森正嗣，保住功，大熊康修，野村靖幸
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2013
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24300135
[Presentation] 自閉症における小胞体ストレスによる神経分化異常の関与
- Author(s)
  家雲高哲，川田浩一，齋藤僚，野村靖幸，大熊康修
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24300135

1. OKUMA Yasunobu (20127939)

# of Collaborated Projects: 11 results

# of Collaborated Products: 99 results
2. KANEKO Masayuki (10322827)

# of Collaborated Projects: 10 results

# of Collaborated Products: 103 results
3. UEHARA Takashi (00261321)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
4. TOHYAMA Masaya (40028593)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
5. MURAYAMA Toshihiko (90174317)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
6. KATADA Toshiaki (10088859)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
7. 田中千賀子 (20025571)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. KITO S (00010140)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
9. TOMOBE Koji (80460286)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
10. TOKUMITU Yukiko (60001046)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
11. ICHIKAWA Atsushi (10025695)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
12. TOHDA Michihisa (20207525)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
13. KIKUCHI Tohru (40025680)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
14. TAKAHASHI Ryosuke (90216771)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
15. Kitamura Yoshihisa (60195295)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
16. UI Michio (50001037)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. HAGA Tatsuya (30011646)

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124. OLSEN R W

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nomura yasuyuki 野村 靖幸

NOMURA Yasuyuki 野村 靖幸

Research Projects

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Co-Researchers

Serotonin transporter gene-linked promotor-polymorphism and DNA methylation involved in personalized impulsivityPrincipal Investigator

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Involvement of novel ubiquitin ligases in the pathogenic mechanism of Alzheimer's disease and drug discovery for fundamental therapeutic agentPrincipal Investigator

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Cognitive science on individual difference of impulsive behavior

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新規ユビキチンリガーゼによる小胞体のタンパク質分解機構

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The inhibitory mechanism of unfolded protein accumulation in the endoplasmic reticulum : Studies on anti-neurodegeneration drug discoveryPrincipal Investigator

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Study on the mechanism underling development of neurodegenerative diseases with age-related dysfunction of the endoplasmic reticulum

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小胞体蓄積タンパク質の分解促進/凝集抑制活性を有する抗脳変性疾患薬の創製Principal Investigator

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The inhibitory mechanism of novel proteins induced in the endoplasmic reticulum and of drugs on neurodegenerative diseasesPrincipal Investigator

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小胞体に蓄積する変性蛋白質の修復/分解系を用いた神経変性疾患防御機構Principal Investigator

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Studies on the Regulatory Mechanism of Neuronal Death: Isolation of Novel Factors and Title of Preparation of Model of Neurodegenerative Disease.Principal Investigator

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小胞体での変性蛋白質分解に関与する分子の単離・同定と神経変性疾患防御機構Principal Investigator

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脳ニューロン・グリア細胞相関系のストレス応答機構に関する細胞分子生物学的研究Principal Investigator

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Preparation of animal model with higher brain dysfunction : studies on evaluation methods of active chemicalsPrincipal Investigator

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nomura yasuyuki 野村靖幸

NOMURA Yasuyuki 野村靖幸