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ISHIKAWA Takatoshi  石川 隆俊

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… Alternative Names

石川 隆敏  イシカワ タカトシ

下山 隆俊

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Researcher Number 30085633
Affiliation (based on the past Project Information) *help 2000 – 2001: National Institution for Academic Degrees, Faculty of University Evaluation and Research, Professor, 構, 教授
2000: 国立大学評価機構, 教授
1997 – 1999: 東京大学, 大学院・医学系研究科, 教授
1989 – 1999: 東京大学, 医学部, 教授
1993 – 1995: 東京大学, 医学部(医), 教授 … More
1991: 東京大学, 医学部(医), 教授
1990: 東京大学, 医学部(医)・病理, 教授
1989 – 1990: 東京大学, 医学部・病理, 教授
1989: 癌研, 実験病理部, 部長
1989: 癌研究所, 実験病理部, 部長
1988: 癌研究所, 実験 病理部, 部長
1988: 癌研究所, 実験病理, 部長
1987 – 1988: (財)癌研究会, 癌研究所・実験病理部, 部長
1986 – 1987: 癌研究所, 実験病理部, 部長
1986: 癌研, 実験病理, 部長
1986: 癌研究会, その他, 研究員
1985: (財)癌研究会, その他, 研究員 Less
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Experimental pathology / Circulatory organs internal medicine / Human pathology / General anatomy (including Histology/Embryology) / Embryonic/Neonatal medicine / Biological Sciences
Keywords
Principal Investigator
DNA修復 / イニシエーション / 化学発癌 / 前癌病変 / 突然変異 / イニシエーター / 発癌の修飾 / DNA複製 / がん遺伝子 / 発癌遺伝子 … More / 細胞周期 / アルキル化DNA / メチルトランスフェラーゼ / DNA鋳型活性 / 活性酸素 / 細胞動態 / 発癌リスク / 宿主・臓器環境 / DNA損傷 / イニシエ-ション / DNA付加体形成 / apoptosis / medulloblastoma / glioblastoma / knockout mice / brain tumor / p53 / neu遺伝子、活性化 / エチルニトロソウレア / neu 遺伝子、活性化 / schwannoma / 経胎盤発癌 / 脳腫瘍 / ノックアウトマウス / p53欠損 / Nitrosamine / Liver carcinogenesis / O^6-methylguanine / Transgenic mice / MGMT / 発癌予防 / DNA損傷修復 / O^6-メチルグアニン / 老化 / トランスジェニックマウス / 発癌 / DNAー発癌物質付加体 / 転写誘導 / 薬物代謝酵素 / p450CYP1A1 / 芳香族炭化水素 / 発がん感受性 / ベンツピレン / 遺伝子ノックアウトマウス / AhR遺伝子 / APエンドヌクレアーゼ / ヒト腫瘍 / MTH1遺伝子 / ミスマッチ修復 / 遺伝子変異 / E2F4 / hMSH3 / replication error / 多型タンパク不安定性 / 遺伝子多型 / 突然変異上昇 / ミューテーター遺伝子 / 細胞回転 / 発癌物質 / 発癌と環境因子 / 発癌と宿主因子 / DNA付加体 / イニシエ-タ- … More
Except Principal Investigator
DNA修復 / 発がん / CYP1A1 / 肝炎ウイルス / C型肝炎 / 肝癌 / DNA付加体 / 代謝的活性化 / Fas / CYP1B1 / Myanmar / hepatocellular carcinoma / Development / Neural crest / Congenital diseases / Gene-targeting / Endothelin-1 / モデル動物 / 胎児発達 / 血圧調節 / エンドセリン / 発生 / 神経堤細胞 / 先天性疾患 / ノックアウト・マウス / ジーンターゲティング / エンドヤリン1 / DNA repair / トランスジェニックマウス / 色素性乾皮症 / Tumor Suppressor Genes / Oncogenes / International Exchange Program / がん抑制遺伝子 / がん遺伝子 / 発がん感受性 / プログレッション / ジメチルベンツアントラセン / 遺伝子ノックアウトマウス / AhR遺伝子 / サラセミア / 鉄過剰症 / ミヤンマー国 / B型肝炎 / 輸血 / ウイルス性肝炎 / アポトーシス / 活性中間体 / 化学発癌 / p53遺伝子 / ras遺伝子 / DNA傷害 / CNーTPBP / ミクロチスチン / モノADPーリボシル化 / ポリADPーリボシル化 / German-Japanese collaborative program in cancer research / French-Japanese collaborative programe in cancer research / Growth Factors / Cytokines / Human Gene Mapping / 増殖因子 / サイトカイン / ヒトがん遺伝子 / ヒトレトロウイルス / molecular histochemistry / Fas ligand / apoptosis / hepatitis viruses / iron-responsive element binding proteins / iron / 肝炎ウィルス / Fasリガンド / 分子組織細胞化学 / Fas リガンド / 鉄反応エレメント結合蛋白 / 鉄 / ミャンマー / Progression / Dibenzo[a, l]pyrene / DMBA / Benzo[a]pyrene / Knockout mice / AhR gene / 転写誘導 / 薬物代謝酵素 / p450CYP1A1 / 芳香族炭化水素 / ジベンゾ[a,l]ピレン / ベンツピレン / Echocardiography / CMV / Lac Z / δ-SG / rAAV / Therapy / Gene / サイコグリカン / リポソーム / 薬物療法 / 細胞骨格蛋白 / 予後 / AAVベクター / サルコグリカン / 遺伝子治療 / 心筋症 / abnormal hemoglobin / hepatitis virus / hepatitis.C / hepatitis.B / thalassemia / iron overload / 自由鉄 / 血清フェリチン / ミヤンマー / 異常ヘモグロビン / 肝細胞癌 / Genetic diagnosis / Polymorphism / Knock-out mouse / 遺伝子診断 / ジーンターダティング / 神経提細胞 / ジ-ソターゲティング / 遺伝子 / 遺伝子多型 / Transgenic mice / Blood pressure / Knock-out mice / 先天性心疾患 / トランスジェニック・マウス / 血圧 / Animal model for disease / Xeroderma pigmentosum / Gene targeting mouse / Transgenic mouse / Methyltransferase / O^6 -methylguanine / 発癌予防 / 0^6-メチルグアニン / 疾患モデル / 遺伝子欠損マウス / メチルトランスフェラーゼ / O^6-メチルグアニン / knockout mice / transgenic mice / alkylating agent / mutation / carcinogenesis / active oxygen / xeroderma pigmentosum / モデルマウス / モデルハウス / 紫外線 / ES細胞 / 遺伝子ターゲッティング / 活性酸素 / ノックアウトマウス / アルキル化剤 / 突然変異 / 活性酵素 / Cancer Metastasis / DNA Repair / Signal Transduction / German-Japanese Collaborative Program in Cancer Research / French-Japanese Collaborative Program in Cancer Research / がん抑制遣伝子 / がん遣伝子 / 2国間共同研究 / ヒトゲノム / がん転移 / がん細胞 / シグナル伝達 / 39KD蛋白質 / 高転移生 / 自然肝発がん / プラスチック / 染 色体欠損 / K-ras / 間接誘発胸腺腫 / 直接誘発胸腺腫 / 放射線 / raf / IQ / モノ(ADP-リボシル)化 / ポリ(ADP-リボシル)化 / プロモーター / 肝発がん / ポリ(ADP-リボース)合成酵素cDNA / モノ(ADP-リボース)合成酵素 / ポリ(ADP-リボース)合成酵素 / 染色体欠失 / ゴールデンハムスター胎児培養細胞 / tcoがん遺伝子 / 新しいがん遺伝子 / rafの発現上昇 / ラット肝がんがん遺伝子 / マウス肝がんがん遺伝子 / モノクローン抗体 / cDNA / ADP-リボシル化 / ポリADP-リボース / IL-2レセプターの発現 / ショウジョウバエの劣性腫瘍遺伝子 / 初期胎児組織 / トランスホーメーション / 初代細胞 / 不死化;myc遺伝子 / ジベンゾ[a, l]ピレン / 鉄代謝 / ヘモグロビン異常症 / マラリア / シャンマー / 鉄欠乏 / 供血者 / p53変異 / 遺伝子検索 / ヘモグロビン等電点電気泳動 / ヤンゴン / 鉄過剰 / ラット肝発癌 / MDM-2 / p21 / PPly2 / ポリ(ADP-リボース)合成酵素(PAP) / Myb / アセチル化酵素 / P450 / 細胞増殖 / チトクロームP-450 / WT遺伝子 / ウサギ腎芽腫 / ラット腎細胞がん / ラット大腸がん / IQによる扁平上皮がん / 食品中発がん物質ヘテロサイクリックアミン / ヒドロキシアリ-ルアミン / 臓器特異性 / 性差 / 種差 / 癌原物質 / rhoタンパク質 / Gタンパク質 / mybタンパク質 / mimー1タンパク質 / モノクロ-ン抗体 / protein kinase C / プロスタグランジンE_2 / 蛋白質脱リン酸化酵素2A / オカダ酸クラス発がんプロモ-タ- / オカダ酸 / メタロチオネイン遺伝子 / ホタル・ルシフェラーゼ / 遺伝子導入細胞 / メタロチオネイン / アラキドン酸代謝 / プロテインフォスファターゼ / カリキュリンA / 発がんプロモーター / オカダ酸クラスプロモーター / 遺伝子発現 / Gータンパク質 / 情報伝達 / モノADPーリボシル化酵素 / ポリADPーリボース合成酵素 / ポリADPーリボース Less
  • Research Projects

    (41 results)
  • Co-Researchers

    (139 People)
  •  AhR遺伝子欠損マウスの発癌抵抗性に関する研究

    • Principal Investigator
      中鶴 陽子
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Effect of iron as an environmental poisonous compound upon the precocious development of human hepatocellular carcinoma in Myanmar

    • Principal Investigator
      KOJI Takehiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Nagasaki University
  •  ミャンマー国肝がん発生要因としての輸血関連疾患と鉄過剰症の調査研究

    • Principal Investigator
      岡田 茂
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  AhR遺伝子欠損マウスの発癌抵抗性に関する研究Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokyo
  •  Role of carcinogenesis in aromatic hydrocarbons in Ah (dioxin) receptor knockout mice

    • Principal Investigator
      NAKATSURU Yoko
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tokyo
  •  ミャンマー国肝癌発生要因としてのサラセミア症の鉄過剰症と輸血関連疾患の調査研究

    • Principal Investigator
      岡田 茂
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Human pathology
    • Research Institution
      Okayama University
  •  Gene therapy of advanced heart failure

    • Principal Investigator
      TOYO-OKA Teruhiko
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  ヒト発がんにおける複製・修復遺伝子の変異Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  Analysis of the brain tumor transplacentally induced in p53 knockout micePrincipal Investigator

    • Principal Investigator
      ISHIKAWA Takatoshi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Hepatocarcinogenetic Studies in Myanmar Thalassemiacs

    • Principal Investigator
      OKADA Shigeru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Human pathology
    • Research Institution
      OKAYAMA UNIVERSITY
  •  腫瘍細胞のDNA機能異常における核タンパク質の相互作用

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Importance of DNA repair in carcinogenesis : Insight for transgene or gene targeting experiments.

    • Principal Investigator
      NAKATSURU Yoko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  ESTABLISHMENT OF MICE DEFICTENT IN A VASOACTIVE PEPTIDE BY GENE TARGETING AND THEIR APPLICATION TO PATHOPHYSIOLOGICAL ANALYSIS

    • Principal Investigator
      KURIHARA Hiroki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      University of Tokyo
  •  ESTABLISHMENT OF AN ANIMAL MODEL FOR CONGENITAL CRANIOFACIAL DISEASES BY GENE TARGETING AND DEVELOPMENT OF THEIR GENETIC DIAGNOSIS.

    • Principal Investigator
      KURIHARA Hiroki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      University of Tokyo
  •  宿主・臓器環境とイニシエーションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓器DNA傷害-臓器および種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  Establishment of DNA repair-deficient or-superproficient mice and their development and molecular basis of genetic instability

    • Principal Investigator
      TANAKA Kiyoji
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Initiation and Its Inhibition by Carcinogenes in transgenic Mice Carried with MGMT Gene.Principal Investigator

    • Principal Investigator
      ISHIKAWA Takatoshi
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Experimental pathology
    • Research Institution
      University of Tokyo
  •  宿主・臓器環境とイニシエーションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓番DNA傷害ー臓器よおび種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  ADPーリボシル化の調節と発がん

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      University of Tsukuba
  •  宿主・臓器環境とイニシエ-ションリスクの変動Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌における活性中間体の動態と標的臓器DNA傷害ー臓器および種特異性との関連

    • Principal Investigator
      加藤 隆一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Keio University
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      NAGAO Minako
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Tokyo
  •  化学発癌におけるイニシエ-ション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  ADPーリボシル化の調節と発がん

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      University of Tsukuba
  •  発がんプロモーションの機構とその阻害

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  遺伝子導入による自己発光性哺乳類細胞の構築とその細胞癌化・分化の解析への応用

    • Principal Investigator
      宇多小路 正
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発がんプロモ-ションの機構とその阻害

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  化学発癌におけるイニシエーション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  化学発癌におけるイニシエーション機構の解析Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Cooperation and Information Exchange with European Countries

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  実験動物がんのがん遺伝子

    • Principal Investigator
      長尾 美奈子
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  細胞の不老不死と腫瘍遺伝子による試験管内発がんの関連

    • Principal Investigator
      近藤 宗平
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kinki University
  •  発がんにおける蛋白質のモノおよびポリADP-リボシル化について

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  発がんにおける蛋白質のモノおよびポリADPリボシル化について

    • Principal Investigator
      三輪 正直
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  発癌のイニシェーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発癌のイニシェーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  •  発癌のイニシエーションの特性と修飾Principal Investigator

    • Principal Investigator
      石川 隆俊
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Japanese Foundation For Cancer Research
  • 1.  NAKATSURU Youko (00237314)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  OKADA Shigeru (20033201)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  多田 万里子 (90073113)
    # of Collaborated Projects: 7 results
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