Kakeya Hideaki 掛谷秀昭

… Alternative Names

KAKEYA Hideaki 掛谷秀昭

掛合秀昭カケヤヒデアキ

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Researcher Number	00270596
Other IDs	https://orcid.org/0000-0002-4293-7331
Affiliation (Current)	2024: 京都大学, 薬学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 京都大学, 薬学研究科, 教授 2015: 京都大学, 大学院薬学研究科, 教授 2015: 京都大学, 薬学研究科(研究院), 教授 2013: 京都大学, 大学院・薬学研究科 2007 – 2009: Kyoto University, 薬学研究科, 教授 … More 2004 – 2006: 独立行政法人理化学研究所, 長田抗生物質研究室, 副主任研究員 2003: 独立行政法人理化学研究所, 抗生物質研究室, 副主任研究員 2000 – 2003: 理化学研究所, 抗生物質研究室, 研究員 1996 – 1998: 理化学研究所, 抗生物質研究室, 研究員 1997: 現代学研究所, 抗生物質研究室, 研究員 Less
Review Section/Research Field	Principal Investigator Science and Engineering / Bioorganic chemistry / Medium-sized Section 37:Biomolecular chemistry and related fields / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Agricultural chemistry and related fields / Bioorganic chemistry / Science and Engineering Except Principal Investigator Transformative Research Areas, Section (II) / Science and Engineering / Science and Engineering / Bioproduction chemistry/Bioorganic chemistry / Biological pharmacy / Circulatory organs internal medicine
Keywords	Principal Investigator ケミカルバイオロジー / 天然物化学 / 複合培養 / 生物活性リガンド / 化学コミュニケーション / 生合成 / 分子社会学 / クリプティック遺伝子 / 細胞死 / ケミカルゲノミクス … More / 天然有機化合物 / ケミカルジェネティクス / 抗がん剤シーズ / 希少天然物 / 生物分子科学 / ケミカルツール / 人工知能（AI） / 分子プローブ / 抗がん剤 / 低酸素誘導因子 / 希少放線菌 / 放線菌 / 抗生物質 / 抗真菌剤 / 生物有機化学 / ケミカルデノミクス / 構造解析 / 細胞周期 / 血管新生 / 精密構造解析 / 機能性天然分子 / 微生物代謝産物 / 血管新生阻害剤 / サイトトリエニン / 化学生物学 / 血管新生阻害財 / 抗癌剤 / 分子シャペロン / デスレセプター / アポトーシス / エポラクタエン類縁体 / エポラクタエン / 神経分化誘導剤 / テロメアDNA / テロメラーゼ / 神経栄養因子 / 神経芽腫 / U937細胞 / alterperylenol / TRAP法 / テロメラーゼ阻害物質 / テロメア配列 … More Except Principal Investigator VHR / ホスファターゼ / isoavenaciolide / アポトーシス / phoslactomycin / Curvularia sp. / 阻害剤 / 構造活性相関 / RK-682 / 分子探索・プロファイリング / 分子プロファイリング / 生理機能解析 / 病理形態解析 / ゲノム編集 / モデル動物作製 / AI創薬 / ハイスループットスクリーニング / 分子プローブ / ケミカルゲノミクス / 標的同定 / MPP / 神経細胞 / 放線菌培養液 / EMT / 前立腺がん / パーキンソン病 / がん / VCP / 作用解析機構 / 天然物リガンド / 難治疾患 / ノナクチン / キサントフモール / アンタルライド / βカテニン / オートファジー / アンドロゲンアンタゴニスト / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / 若手支援 / dephosphorylation / apoptosis / biosynthesis / inhibitor / phosphatase / テトロン酸 / 分子設計 / 活性中心 / Michael付加 / 4-isoavenaciolide / リン酸化 / Bcl-2 / 脱リン酸化 / 生合成系 / trichotecene / sesquiterpene / new compound / cell cycle / protein synthesis inhibition / G1 phase / ホスミドシン / テルペプチン / サイクリン / サイトカラシン / トリプロスタチン / チユープリン / ビオチン標識 / ピロネチン / チューブリン / 微小管 / 細胞周期阻害剤 / トリコテセン / セスキテルペン / 新規化合物 / 細胞周期 / 蛋白質合成阻害 / G1期 / SV40T antigen / DNA helicase / saponin / anti-cancer drugs / inhibitors / cell-free system / DNA repair / DNA replication / SV40 T抗原 / DNAヘリカーゼ / サポニン / 抗がん剤 / 無細胞系 / DNA修復 / DNA複製 / 心肥大 / 動脈瘤 / 脂肪肝 / SREBP-1 / SREBP-2 / ABCA1 / 動脈硬化 / HDL-C / マイクロRNA / 標的分子 / 結晶構造解析 / 低分子化合物 / ライブラリー / 化合物アレイ / リガンド / 受容体 / 相互作用 / 蛋白質 / バイオプローブ / 構造生物学 / 化学生物学 / ホスファトキノン / RK-1009 / ホスラクトマイシン / 拮抗阻害 Less

Development of scarce natural products and innovative anticancer seedsPrincipal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kyoto University
Chemical genetic approach to mode of action and biological validation of compounds from latent chemical space
- Principal Investigator
  
  吉田稔
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Institute of Physical and Chemical Research
先端モデル動物支援プラットフォーム
- Principal Investigator
  
  武川睦寛
- Project Period (FY)
  2022 – 2027
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (platforms for Advanced Technologies and Research Resources)
- Research Institution
  The University of Tokyo
Frontier research on chemical communicationsPrincipal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Chemical biology on a bioactive substance regulating the hypoxia response signalPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kyoto University
Biosynthetic research on cryptic gene activationPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Agricultural chemistry and related fields
- Research Institution
  Kyoto University
Chemical communications in microbial interactions and development of useful bioactive ligandsPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Frontier research of chemical communicationsArea Organizer
- Area Organizer
  
  掛谷秀昭
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Frontiers in Chemical CommunicationsPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Chemical biology on cryptic genes activationPrincipal Investigator
- Principal Investigator
  
  Kakeya Hideaki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bioorganic chemistry
- Research Institution
  Kyoto University
Elucidation of the functions of miR-33a/b in cholesterol homeostasis
- Principal Investigator
  
  ONO KOH
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyoto University
Discovery of natural products that modulate cellular responses
- Principal Investigator
  
  Imoto Masaya
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Keio University
Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas
- Principal Investigator
  
  IMAI Kohzoh, 中村祐輔
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  The University of Tokyo
Chemical proteomics to reveal interaction between chemicals and proteins at angstrom level
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Creative Scientific Research
- Research Institution
  The Institute of Physical and Chemical Research
微生物代謝産物由来の機能性天然分子の探索・創製と応用研究Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
細胞死を制御する天然有機化合物の化学生物学的解析Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Chemical biology study on protein phosphatases and their specific inhibitors.
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  RIKEN
デュアルスペシフィックホスファターゼの阻害剤開発と機能探索
- Principal Investigator
  
  長田裕之
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The Institute of Physical and Chemical Research
デュアルスペシフィックホスファターゼの阻害剤開発と機能探索
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Institute of Physical and Chemical Research
神経芽腫細胞における神経細胞分化誘導とテロメラーゼ活性に関する研究Principal Investigator
- Principal Investigator
  
  掛谷秀昭
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Isolation and mechanism study of cell cycle inhibitors from microbial metabolites.
- Principal Investigator
  
  OSADA Hiroyuki
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  RIKEN
Search for Novel Anti-cancer Drugs Targetting DNA Replication and Repair
- Principal Investigator
  
  HANAOKA Fumio
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka University

[Book] くすりの科学知識-今こそ知っておきたいくすりの効能、しくみ、正しい付き合い方-（増補第3版）2021
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  175
- Publisher
  ニュートンプレス社
- ISBN
  9784315524642
- Data Source
  KAKENHI-PROJECT-19H02840
[Book] くすり大図鑑2021
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  206
- Publisher
  ニュートンプレス社
- ISBN
  9784315524802
- Data Source
  KAKENHI-PROJECT-19H02840
[Book] くすり大図鑑, Newton大図鑑シリーズ2021
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  206
- Publisher
  ニュートンプレス社
- ISBN
  9784315524802
- Data Source
  KAKENHI-PLANNED-17H06401
[Book] くすりの科学知識-今こそ知っておきたいくすりの効能、しくみ、正しい付き合い方-（増補第3版）2021
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  175
- Publisher
  ニュートンプレス社
- ISBN
  9784315524642
- Data Source
  KAKENHI-PLANNED-17H06401
[Book] くすりの科学知識（増補第2版）2019
- Author(s)
  掛谷秀昭
- Total Pages
  175
- Publisher
  ニュートンプレス
- ISBN
  9784315521894
- Data Source
  KAKENHI-PLANNED-17H06401
[Book] くすりの科学知識：薬のしくみと、奥深き創薬の世界2019
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  175
- Publisher
  ニュートンプレス
- ISBN
  9784315521894
- Data Source
  KAKENHI-PROJECT-19H02840
[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  144
- Publisher
  ニュートンプレス社
- ISBN
  9784315520835
- Data Source
  KAKENHI-PROJECT-17K19233
[Book] 1. 薬の基礎知識 & 2. 創薬の世界, Newton 別冊「くすりの科学知識：くすりのしくみと、奥深き創薬の世界」2017
- Author(s)
  掛谷秀昭（監修）
- Total Pages
  144
- Publisher
  ニュートンプレス社
- ISBN
  9784315520835
- Data Source
  KAKENHI-PLANNED-17H06401
[Book] 特集・制がん剤の分子標的スクリーニング成績化学療法基盤支援活動報告-制がん候補物質のスクリーニング成績・第15報2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] 特集・制がん剤の分子標的スクリーニング成績「化学療法基盤情報支援班」報告‐制がん候補物質のスクリーニング成績・第15報『癌と化学療法オンライン』2013
- Author(s)
  矢守隆夫, 上原至雅, 深澤秀輔, 吉田稔, 井本正哉, 清宮啓之, 馬島哲夫, 水上民夫, 川田学, 長田裕之, 旦慎吾, 松浦正明, 掛谷秀昭, 冨田章弘.
- Publisher
  癌と化学療法社
- Data Source
  KAKENHI-PROJECT-221S0001
[Book] インシリコ創薬科学 -ゲノム情報から創薬へ-「創薬研究における化合物ライブラリー」2008
- Author(s)
  掛谷秀昭, 他
- Total Pages
  210
- Publisher
  京都廣川書店
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Development and application of highly sensitive labeling reagents for amino acids2022
- Author(s)
  Kuranaga, T., Kakeya, H.
- Journal Title
  
  Methods in Enzymol.
  
  Volume: 665 Pages: 105-133
- DOI
  10.1016/bs.mie.2021.11.004
- ISBN
  9780323952675
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Developing crosslinkers specific for epimerization domain to elucidate mechanism2022
- Author(s)
  Woojoo E. Kim, Fumihiro Ishikawa, Rebecca N. Re, Takehiro Suzuki, Naoshi Dohmae, Hideaki Kakeya, Genzoh Tanabe, Michael D. Burkart
- Journal Title
  
  RSC Chem. Biol.
  
  Volume: 3 Issue: 3 Pages: 312-319
- DOI
  10.1039/d2cb00005a
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05722, KAKENHI-PLANNED-17H06401
[Journal Article] Chemoproteomics profiling of surfactin-producing nonribosomal peptide synthetases in living bacterial cells2022
- Author(s)
  Fumihiro Ishikawa, Sho Konno, Chiharu Uchida, Takehiro Suzuki, Katsuki Takashima, Naoshi Dohmae, Hideaki Kakeya, Genzoh Tanabe
- Journal Title
  
  Cell Chem. Biol.
  
  Volume: 29 Issue: 1 Pages: 1-12
- DOI
  10.1016/j.chembiol.2021.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05722, KAKENHI-PLANNED-17H06401
[Journal Article] Identification and total synthesis of an unstable anticancer macrolide presaccharothriolide Z produced by Saccharothrix sp.2021
- Author(s)
  Kuranaga, T., Tamura, M., Ikeda, H., Terada, S., Nakagawa, Y., Kakeya, H.
- Journal Title
  
  Org. Lett.
  
  Volume: 23 Pages: 7106-7111
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] An atypical arginine dihydrolase involved in the biosynthesis of cyclic hexapeptide longicatenamides.2021
- Author(s)
  Liu, C., Hashimoto, J., Kudo, K., Shin-ya, K., Kakeya, H.
- Journal Title
  
  Chem. Asian J.
  
  Volume: 16 Issue: 11 Pages: 1382-1387
- DOI
  10.1002/asia.202100181
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Application of the highly sensitive labeling reagent to the structural confirmation of readily isomerizable peptides2021
- Author(s)
  an, C., Kuranaga, T., Kakeya, H.
- Journal Title
  
  J. Nat. Med.
  
  Volume: 75 Issue: 2 Pages: 339-343
- DOI
  10.1007/s11418-020-01472-z
- NAID
  40022508940
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Toward the Creation of Induced Pluripotent Small (iPS) Molecules: Establishment of a Modular Synthetic Strategy for the Heronamide C-type Polyene Macrolactams and Their Conformational and Reactivity Analysis2021
- Author(s)
  Kanoh Naoki、Terajima Yuta、Tanaka Suguru、Terashima Ryusei、Nishiyama Hiromichi、Nagasawa Shota、Sasano Yusuke、Iwabuchi Yoshiharu、Nishimura Shinichi、Kakeya Hideaki
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 23 Pages: 16231-16248
- DOI
  10.1021/acs.joc.1c01760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06990, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H03347
[Journal Article] Longicatenamides A-D, two diastereomeric pairs of cyclic hexapeptides produced by combined-culture of Streptomyces sp. KUSC_F05 and Tsukamurella pulmonis TP-B05962021
- Author(s)
  Jiang, Y., Matsumoto, T., Kuranaga, T., Lu, S., Wang, W., Onaka, H., Kakeya, H.
- Journal Title
  
  J. Antibiot.
  
  Volume: - Issue: 5 Pages: 307-316
- DOI
  10.1038/s41429-020-00400-3
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-19H02840
[Journal Article] Heterogenous chemosensitivity of organoid cell lines derived from small cell neuroendocrine carcinoma of the uterine cervix2021
- Author(s)
  Tanaka, M., Kondo, J., Kaneko, K., Endo, H., Onuma, K., Coppo, R., Kamiura, S., Yoshino, K., Ueda, Y., Kakeya, H. Kimura, T., Inoue, M.
- Journal Title
  
  Human Cell
  
  Volume: - Issue: 3 Pages: 889-900
- DOI
  10.1007/s13577-021-00511-5
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02648, KAKENHI-PROJECT-19H02840
[Journal Article] Genomic and Targeted Approaches Unveil the Cell Membrane as a Major Target of the Antifungal Cytotoxin Amantelide A2021
- Author(s)
  Elsadek Lobna A.、Matthews James H.、Nishimura Shinichi、Nakatani Takahiro、Ito Airi、Gu Tongjun、Luo Danmeng、Salvador‐Reyes Lilibeth A.、Paul Valerie J.、Kakeya Hideaki、Luesch Hendrik
- Journal Title
  
  ChemBioChem
  
  Volume: in press Issue: 10 Pages: 1790-1799
- DOI
  10.1002/cbic.202000685
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06717, KAKENHI-PLANNED-17H06401
[Journal Article] Amycolapeptins A and B, cyclic nonadepsipeptides produced by combined-culture of Amicolatopsis sp. and Tsukamurella pulmonis2021
- Author(s)
  Pan, C., Kuranaga, T., Cao, X., Suzuki, T., Dohmae, N., Shinzato, N., Onaka, H., Kakeya, H.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 86 Issue: 2 Pages: 1843-1849
- DOI
  10.1021/acs.joc.0c02660
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-19H02840
[Journal Article] Highly Sensitive Determination of Amino Acids by LC-MS under Neutral Conditions2021
- Author(s)
  Morimoto, R., Matsumoto, T., Minote, M., Yanagisawa, M., Yamada, R., Kuranaga, T., Kakeya, H.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 69 Issue: 3 Pages: 265-270
- DOI
  10.1248/cpb.c20-00958
- NAID
  130007993065
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Design, synthesis, and target identification of new hypoxia-induced factor 1 (HIF-1) inhibitors containing 1-alkyl-1H-pyrazole-3-carboxamide moiety2021
- Author(s)
  Sakai, M., Takahashi, N., Ikeda, H., Furutani, Y., Higuchi, S., Suzuki, T., Dohmae, N., Kobayashi, S., Harada, H., Kojima, S., Matsuura, T., Hattori, A., Kakeya, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: - Pages: 116375-116375
- DOI
  10.1016/j.bmc.2021.116375
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Amphiol, an antifungal pigment from Pseudogymnoascus sp. PF14642021
- Author(s)
  Fujita, K., Ikuta, M., Nishimura, S., Sugiyama, R., Yoshimura, A., Kakeya, H.
- Journal Title
  
  J. Nat. Prod.
  
  Volume: - Issue: 4 Pages: 986-992
- DOI
  10.1021/acs.jnatprod.0c01010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18K06717
[Journal Article] Inhibition of efflux pumps aids small-molecule probe-based fluorescence labeling and imaging in the Gram-negative bacterium Escherichia coli2021
- Author(s)
  Fumihiro Ishikawa, Sho Konno, Katsuki Takashima, Hideaki Kakeya, Genzoh Tanabe
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 19 Issue: 41 Pages: 8906-8911
- DOI
  10.1039/d1ob01112j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05722, KAKENHI-PLANNED-17H06401
[Journal Article] Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats2021
- Author(s)
  Sunagawa Yoichi、Funamoto Masafumi、Shimizu Kana、Shimizu Satoshi、Sari Nurmila、Katanasaka Yasufumi、Miyazaki Yusuke、Kakeya Hideaki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 8 Pages: 2608-2608
- DOI
  10.3390/nu13082608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-21K08069
[Journal Article] 希少放線菌と異属微生物間化学コミュニケーションを活用したケミカルスペース拡充戦略2021
- Author(s)
  掛谷秀昭
- Journal Title
  
  ファインケミカル
  
  Volume: 50 Pages: 33-39
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy.2021
- Author(s)
  Ikeda, H., Kakeya, H.
- Journal Title
  
  J. Antibiot.
  
  Volume: 74 Issue: 10 Pages: 687-695
- DOI
  10.1038/s41429-021-00451-0
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Curcumin β-D-Glucuronide Modulates an Autoimmune Model of Multiple Sclerosis with Altered Gut Microbiota in the Ileum and Feces2021
- Author(s)
  Khadka Sundar、Omura Seiichi、Sato Fumitaka、Nishio Kazuto、Kakeya Hideaki、Tsunoda Ikuo
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 772962-772962
- DOI
  10.3389/fcimb.2021.772962
- NAID
  120007173781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08569, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06404, KAKENHI-PROJECT-20K07433, KAKENHI-PROJECT-20K07455
[Journal Article] Retro-aza-Michael reaction of an o-aminophenol adduct in protic solvents inspired by natural products2021
- Author(s)
  Takenaka, K., Kaneko, K., Takahashi, N., Nishimura, S., Kakeya, H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: - Pages: 116059-116059
- DOI
  10.1016/j.bmc.2021.116059
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Design, Synthesis, and Antifungal Activity of 16,17-Dihydroheronamide C and <i>ent</i>-Heronamide C2021
- Author(s)
  Kanoh Naoki、Terashima Ryusei、Nishiyama Hiromichi、Terajima Yuta、Nagasawa Shota、Sasano Yusuke、Iwabuchi Yoshiharu、Saito Hiroaki、Egoshi Syusuke、Dodo Kosuke、Sodeoka Mikiko、Pan Chengqian、Ikeuchi Yoshinobu、Nishimura Shinichi、Kakeya Hideaki
- Journal Title
  
  The Journal of Organic Chemistry
  
  Volume: 86 Issue: 23 Pages: 16249-16258
- DOI
  10.1021/acs.joc.1c01761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06990, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H04791, KAKENHI-PROJECT-19H03347, KAKENHI-PROJECT-19K05378, KAKENHI-PROJECT-20K15418
[Journal Article] Methylation deficiency disrupts biological rhythms from bacteria to humans2020
- Author(s)
  Fustin, J.M., Ye, S., Rakers, C., Kaneko, K., Fukumoto, K., et al., Kakeya, H., Van Ooijen, G., Okamura, H.
- Journal Title
  
  Commun. Biol.
  
  Volume: 3 Pages: 211-211
- NAID
  120006846495
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Different localization of lysosomal-associated membrane protein 1 (LAMP1) in mammalian cultured cell lines2020
- Author(s)
  Kosuke Baba, Sara Kuwada, Ayaka Nakao, Xuebing Li, Naoaki Okuda, Ai Nishida, Satoshi Mitsuda, Natsuki Fukuoka, Hideaki Kakeya, Takao Kataoka
- Journal Title
  
  Histochemistry and Cell Biology
  
  Volume: 153 Issue: 4 Pages: 199-213
- DOI
  10.1007/s00418-019-01842-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02885, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice.2020
- Author(s)
  Shimizu K, Sunagawa Y, Funamoto M, Wakabayashi H, Genpei M, Miyazaki Y, Katanasaka Y, Sari N, Shimizu S, Katayama A, Shibata H, Iwabuchi Y, Kakeya H, Wada H, Hasegawa K, Morimoto T.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 7172-7172
- DOI
  10.1038/s41598-020-64207-w
- NAID
  120006888478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08279, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18K08121
[Journal Article] The effects of 5‐OP‐RU stereochemistry on its stability and MAIT‐MR1 axis2020
- Author(s)
  Matsuoka Takuro、Motozono Chihiro、Hattori Akira、Kakeya Hideaki、Yamasaki Sho、Oishi Shinya、Ohno Hiroaki、Inuki Shinsuke
- Journal Title
  
  ChemBioChem
  
  Volume: 22 Issue: 4 Pages: 672-678
- DOI
  10.1002/cbic.202000466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06938, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-20H04773, KAKENHI-PROJECT-19K07623
[Journal Article] Curcumin beta-D-glucuronide (CMG) exhibits anti-tumor effects on oxaliplatin-resistant colon cancer with less toxicity.2020
- Author(s)
  Ozawa-Umeta, H., Kishimoto, A., Imaizumi, A., Hashimoto, T., Kakeya, H., Kanai, M.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 5 Pages: 1785-1793
- DOI
  10.1111/cas.14383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Cryptic chemical communication: Secondary metabolic responses revealed by microbial co-culture.2020
- Author(s)
  Liu, C., Kakeya, H.
- Journal Title
  
  Chem. Asian. J.
  
  Volume: 15 Issue: 3 Pages: 327-337
- DOI
  10.1002/asia.201901505
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Total synthesis and antimicrobial activity of tumescenamide C and its derivatives.2020
- Author(s)
  Takahashi, N., Kaneko, K., Kakeya, H.
- Journal Title
  
  J. Org. Chem.
  
  Volume: 85 Issue: 6 Pages: 4530-4535
- DOI
  10.1021/acs.joc.9b03516
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Serinr catabolism produce ROS, sensitizes cells to actin dysfunction, and suppresses cell growth in fission yeast.2020
- Author(s)
  Kanou, A., Nishimura, S., Tabuchi, T., Matsuyama, A., Yoshida, M., Kato, T., Kakeya, H.
- Journal Title
  
  J. Antibiot.
  
  Volume: 73 Issue: 8 Pages: 574-580
- DOI
  10.1038/s41429-020-0305-6
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H05640
[Journal Article] Highly sensitive labeling reagents for scarce natural products2020
- Author(s)
  Kuranaga, T., Minote, M., Morimoto, R., Pan, C., Ogawa, H., Kakeya, H
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 15 Issue: 9 Pages: 2499-2506
- DOI
  10.1021/acschembio.0c00517
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Thioamycolamides A-E, Sulfur-Containing Cycliclipopeptides Produced by the Rare Actinomycete Amycolatopsis sp.2020
- Author(s)
  Chengqian Pan, Takefumi Kuranaga, Chao Liu, Shan Lu, Naoya Shinzato, Hideaki Kakeya
- Journal Title
  
  Org. Lett.
  
  Volume: 22 Issue: 8 Pages: 3014-3017
- DOI
  10.1021/acs.orglett.0c00776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14396, KAKENHI-PLANNED-17H06401
[Journal Article] Total synthesis of thioamycolamide A via a biomimetic route2020
- Author(s)
  Pan, C., Kuranaga, T., Kakeya, H.
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 18 Issue: 41 Pages: 8366-8370
- DOI
  10.1039/d0ob01942a
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Miclxin, a novel MIC60 inhibitor, induces apoptosis via mitochondrial stress in β-catenin mutant tumor cells.2020
- Author(s)
  20)Ikeda, H., Muroi, M., Kondoh, Y., Ishikawa, S., Kakeya, H., Osada, H., Imoto, M.
- Journal Title
  
  ACS Chem. Biol.
  
  Volume: 15 Issue: 8 Pages: 2195-2204
- DOI
  10.1021/acschembio.0c00381
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K05857, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06412, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-18H02099, KAKENHI-PROJECT-18K05366, KAKENHI-PROJECT-16H06276
[Journal Article] Effects of Highly Absorbable Curcumin in Patients with Impaired Glucose Tolerance and Non-Insulin-Dependent Diabetes Mellitus2019
- Author(s)
  Funamoto Masafumi、Shimizu Kana、Sunagawa Yoichi、Katanasaka Yasufumi、Miyazaki Yusuke、Kakeya Hideaki、Yamakage Hajime、Satoh-Asahara Noriko、Wada Hiromichi、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Journal of Diabetes Research
  
  Volume: 2019 Pages: 1-7
- DOI
  10.1155/2019/8208237
- NAID
  120006888005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08121, KAKENHI-PLANNED-17H06401
[Journal Article] Theonellamide A, a marine-sponge-derived bicyclic peptide, binds to cholesterol in aqueous DMSO: Solution NMR-based analysis of peptide-sterol interactions using hydroxylated sterol2019
- Author(s)
  Cornelio Kimberly、Espiritu Rafael Atillo、Hanashima Shinya、Todokoro Yasuto、Malabed Raymond、Kinoshita Masanao、Matsumori Nobuaki、Murata Michio、Nishimura Shinichi、Kakeya Hideaki、Yoshida Minoru、Matsunaga Shigeki
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Biomembranes
  
  Volume: 1861 Issue: 1 Pages: 228-235
- DOI
  10.1016/j.bbamem.2018.07.010
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19149, KAKENHI-PLANNED-17H06401, KAKENHI-PLANNED-17H06406, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-16H06315, KAKENHI-PUBLICLY-16H00773, KAKENHI-PROJECT-15H03121, KAKENHI-PROJECT-26221204
[Journal Article] Enhancement of saccharothriolide production and discovery of a new metabolite, saccharothriolide C2, by combined-culture of Saccharothrix sp. and Tsukamurella pulmonis2019
- Author(s)
  Yulu Jiang, Shan Lu, Go Hirai, Taira Kato, Hiroyasu Onaka, Hideaki Kakeya
- Journal Title
  
  Tetrahedron Lett.
  
  Volume: 60 Issue: 15 Pages: 1072-1074
- DOI
  10.1016/j.tetlet.2019.03.034
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-17K19233, KAKENHI-PUBLICLY-18H04417, KAKENHI-PROJECT-18H02097
[Journal Article] 研究トピックス：がんと宿主の化学コミュニケーション阻害を指向した水溶性プロドラッグ型抗がん剤CMGの開発研究2019
- Author(s)
  掛谷秀昭
- Journal Title
  
  新学術領域研究「化学コミュニケーションのフロンティア」・Newsletter
  
  Volume: 3 Pages: 10-10
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Isolation, Structure Elucidation, and Conformational Regulation of Myropeptins, Lipopeptides from the Fungus Myrothecium roridum.2019
- Author(s)
  Yoshimura, A., Nishimura, S.*, Suzuki, T., Hattori, A., Dohmae, N., Kato, T. & Kakeya, H.
- Journal Title
  
  Org. Lett.
  
  Volume: 21 Issue: 18 Pages: 7524-7528
- DOI
  10.1021/acs.orglett.9b02801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06717, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Development of an anti-hepatitisB virus (HBV) agent through the structure-activity relationship of theinterferon-like small compound CDM-30082019
- Author(s)
  Nobuaki Takahashi, Kyohei Hayashi, Yusuke Nakagawa, Yutaka Furutani, Mariko Toguchi, Yumi Shiozaki-Sato, Masayuki Sudoh, Soichi Kojima, Hideaki Kakeya
- Journal Title
  
  10.1016/j.bmc.2018.11.039
  
  Volume: 27 Pages: 470-478
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Ubiquitin carboxyl‐terminal hydrolase L1 promotes hypoxia‐inducible factor 1‐dependent tumor cell malignancy in spheroid models2019
- Author(s)
  Li Xuebing、Hattori Akira、Takahashi Senye、Goto Yoko、Harada Hiroshi、Kakeya Hideaki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 1 Pages: 239-252
- DOI
  10.1111/cas.14236
- NAID
  120006848248
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22595, KAKENHI-PROJECT-18KK0241, KAKENHI-PLANNED-17H06401, KAKENHI-PUBLICLY-18H04977, KAKENHI-PROJECT-17H04261, KAKENHI-PROJECT-19H02840
[Journal Article] Total synthesis of verucopeptin, an inhibitor of hypoxia-inducible factor 1 (HIF-1).2019
- Author(s)
  Takahashi, N., Hayashi, H., Poznaks, V., Kakeya, H.
- Journal Title
  
  Chem. Commun.
  
  Volume: 55 Issue: 79 Pages: 11956-11959
- DOI
  10.1039/c9cc06169j
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-19H02840
[Journal Article] Identification of the common biosynthetic gene cluster for both antimicrobial streptoaminals and antifungal 5-alkyl-1,2,3,4-tetrahydroquinolines2019
- Author(s)
  Ozaki Taro、Sugiyama Ryosuke、Shimomura Morito、Nishimura Shinichi、Asamizu Shumpei、Katsuyama Yohei、Kakeya Hideaki、Onaka Hiroyasu
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 17 Issue: 9 Pages: 2370-2378
- DOI
  10.1039/c8ob02846j
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K05385, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-17K19233, KAKENHI-PLANNED-16H06444
[Journal Article] Chemical Interactions of Cryptic Actinomycete Metabolite 5‐Alkyl‐1,2,3,4‐tetrahydroquinolines through Aggregate Formation2019
- Author(s)
  Sugiyama Ryosuke、Nakatani Takahiro、Nishimura Shinichi、Takenaka Kei、Ozaki Taro、Asamizu Shumpei、Onaka Hiroyasu、Kakeya Hideaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 58 Issue: 38 Pages: 13486-13491
- DOI
  10.1002/anie.201905970
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05385, KAKENHI-PROJECT-18K06717, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18H02120, KAKENHI-PROJECT-19H02840
[Journal Article] 研究トピックス：微生物間化学コミュニケーションの利活用によるケミカルスペース拡充戦略2019
- Author(s)
  掛谷秀昭
- Journal Title
  
  新学術領域研究「化学コミュニケーションのフロンティア」・Newsletter
  
  Volume: 3 Pages: 9-9
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] 生体膜を標的にする天然有機化合物：天然物による厳密な脂質認識とそれに基づく表現型2018
- Author(s)
  西村慎一, 掛谷秀昭, 松森信明
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 678-685
- NAID
  130007709540
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] Curcumin and its demethoxy derivatives possess p300HAT inhibitory activity and suppress hypertrophic response in cardiomyocytes2018
- Author(s)
  Yoichi Sunagawa, Masafumi Funamoto, Shogo Sono, Kana Shimizu, Satoshi Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Eriko Morimoto, Morio Ueno, Maki Komiyama, Hideaki Kakeya, Hiromichi Wada, Koji Hasegawa, Tasuya Morimoto
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 136 Issue: 4 Pages: 212-217
- DOI
  10.1016/j.jphs.2017.12.013
- NAID
  120006501305
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Natural products-inspired chemical biology toward developmentof new antibiotics2018
- Author(s)
  Hideaki Kakeya
- Journal Title
  
  Jpn. J. Antibiot.
  
  Volume: 71 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] Activity-Based Protein Profiling of Non-ribosomal Peptide Synthetases2018
- Author(s)
  Ishikawa Fumihiro、Tanabe Genzoh、Kakeya Hideaki
- Journal Title
  
  Curr. Top. Microbiol. Immunol.
  
  Volume: 420 Pages: 321-349
- DOI
  10.1007/82_2018_133
- ISBN
  9783030111427, 9783030111434
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] Natural products-inspired chemical biology toward developmentof new antibiotics2018
- Author(s)
  Hideaki Kakeya
- Journal Title
  
  Jpn. J. Antibiot.
  
  Volume: 71 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] 生体膜を標的にする天然有機化合物：天然物による厳密な脂質認識とそれに基づく表現型2018
- Author(s)
  西村慎一, 掛谷秀昭, 松森信明
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 678-685
- NAID
  130007709540
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401
[Journal Article] Discovery Scienceに魅せられて：天然物創薬ケミカルバイオロジーの最前線2018
- Author(s)
  掛谷秀昭
- Journal Title
  
  化学と生物
  
  Volume: 56 Pages: 210-216
- NAID
  130007601848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19233
[Journal Article] Discovery of presaccharothriolide X, a retro-Michael product of saccharothriolide B, from the rare actinomycete Saccharothrix sp. A15062018
- Author(s)
  Shan Lu, Shinichi Nishimura, Kei Takenaka, Masashi Ito, Taira Kato, Hideaki Kakeya
- Journal Title
  
  Org. Lett.
  
  Volume: 20 Issue: 15 Pages: 4406-4410
- DOI
  10.1021/acs.orglett.8b01535
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-17K19233
[Journal Article] A chemoproteomics platform to investigate phosphopantetheine transferase activity at the cellular level2017
- Author(s)
  Konno, S., Ishikawa, F., Suzuki, T., Dohmae, N., Kakeya, H., Tanabe, G.
- Journal Title
  
  ChemBioChem
  
  Volume: 18 Issue: 18 Pages: 1855-1862
- DOI
  10.1002/cbic.201700301
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] 創薬ケミカルバイオロジー：自然に学ぶ薬づくり2017
- Author(s)
  掛谷秀昭
- Journal Title
  
  「くすりをつくる研究者の仕事―薬のタネ探しから私たちに届くまで」
  
  Volume: - Pages: 63-82
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Visualizing the adenylation activities and protein-protein interactions of aryl acid adenylating enzymes2017
- Author(s)
  Ishikawa, F., Kasai, S., Kakeya, H., Tanabe, G.
- Journal Title
  
  ChemBioChem
  
  Volume: 18 Issue: 22 Pages: 2199-2204
- DOI
  10.1002/cbic.201700361
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-17H05438, KAKENHI-PLANNED-17H06401
[Journal Article] Curcumin β-D-Glucuronide Plays an Important Role to Keep High Levels of Free-Form Curcumin in the Blood2017
- Author(s)
  Ozawa, H., Imaizumi, A., Sumi, Y., Hashimoto, T., Kanai, M., Makino, Y., Tsuda, T., Takahashi, N., Kakeya, H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 9 Pages: 1515-1524
- DOI
  10.1248/bpb.b17-00339
- NAID
  130006038773
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07804, KAKENHI-PLANNED-17H06401
[Journal Article] Precursor-directed in situ synthesis of saccharothriolides G and H by the actinomycete Saccharothrix sp.2017
- Author(s)
  Shan Lu, Shinich Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Journal Title
  
  J. Antibiot.
  
  Volume: 70 Issue: 5 Pages: 718-720
- DOI
  10.1038/ja.2016.153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19233, KAKENHI-PLANNED-17H06401
[Journal Article] Natural products-prompted chemical biology: Phenotypic screening and a new platform for target identification2016
- Author(s)
  Kakeya, H.
- Journal Title
  
  Nat. Prod. Rep.
  
  Volume: 33 Issue: 5 Pages: 648-654
- DOI
  10.1039/c5np00120j
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Discovery and Total Synthesis of Streptoaminals: Antimicrobial [5,5]-Spirohemiaminals from 　the Combined-Culture of Streptomyces nigrescens and Tsukamurella pulmonis.2016
- Author(s)
  Sugiyama R, Nishimura S, Ozaki T, Asamizu S, Onaka H, Kakeya H.
- Journal Title
  
  Angew Chem Int Ed Engl.
  
  Volume: 55(35) Issue: 35 Pages: 10278-10282
- DOI
  10.1002/anie.201604126
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25292046, KAKENHI-PROJECT-25702048, KAKENHI-PROJECT-15K14721, KAKENHI-PROJECT-16K18673
[Journal Article] 感染症の脅威と闘う―ヒトマイクロバイオームと特殊培養デバイスの活用2016
- Author(s)
  都築健悟, 掛谷秀昭
- Journal Title
  
  化学
  
  Volume: 71 Pages: 70-71
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] 5-Alkyl-1,2,3,4-tetrahydroquinolines, New Membrane-Interacting Lipophilic Metabolites Produced by Combined Culture of Streptomyces nigrescens and Tsukamurella pulmonis.2015
- Author(s)
  Sugiyama R, Nishimura S, Ozaki T, Asamizu S, Onaka H, Kakeya H.
- Journal Title
  
  Org Lett.
  
  Volume: 印刷中 Issue: 8 Pages: 1918-1921
- DOI
  10.1021/acs.orglett.5b00607
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25292046, KAKENHI-PROJECT-25702048, KAKENHI-PUBLICLY-26102726, KAKENHI-PROJECT-26850044, KAKENHI-PROJECT-15K14721
[Journal Article] 創薬ケミカルバイオロジー：シード分子開発と分子プロファイリング2015
- Author(s)
  掛谷秀昭
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 119-125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Design, synthesis and structure-activity relationships of 1-ethylpyrazole-3-carboxamide as novel HIF-1 inhibitors2015
- Author(s)
  Yasuda Y, Arakawa T, Nawata Y, Shimada S, Oishi S, Fujii N, Nishimura S, Hattori A, Kakeya H
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 23 Issue: 8 Pages: 1776-1787
- DOI
  10.1016/j.bmc.2015.02.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] 生体膜微小環境への挑戦：膜ステロールに作用する海洋天然物セオネラミド2015
- Author(s)
  西村慎一, 掛谷秀昭
- Journal Title
  
  CSJカレントレビュー19号（日本化学会編）「生物活性分子のケミカルバイオロジー」
  
  Volume: 19 Pages: 102-108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14721
[Journal Article] Chemical tagging of a drug target using 5-sulfonyl tetrazole2013
- Author(s)
  Otsuki S, Nishimura S, Takabatake H, Nakajima K, Takasu Y, Yagura T, Sakai Y, Hattori A, & Kakeya H
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 23 Issue: 6 Pages: 1608-1611
- DOI
  10.1016/j.bmcl.2013.01.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310160, KAKENHI-PROJECT-24659099, KAKENHI-PROJECT-221S0001
[Journal Article] 特集号「日本の天然物化学の展望-生命科学解明の機能分子、新たな創薬分子として-」;新規有用天然有機化合物の開拓とケミカルバイオロジー研究2010
- Author(s)
  掛谷秀昭, et al
- Journal Title
  
  有機合成化学協会誌
  
  Volume: 68 Pages: 490-500
- Data Source
  KAKENHI-PROJECT-221S0001
[Journal Article] Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.2009
- Author(s)
  Kakeya, H. (10名中5番目), Usui, T. (10名中7番目), Takahashi, S. (10名中8番目), Osada, H. (10名中10番目)
- Journal Title
  
  Chembiochem 23
  
  Pages: 920-928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] A fungal metabolite, epoxyquinol B inhibits the NF-kappaB signal through the crosslinking of TAK1.2008
- Author(s)
  Usui, T. (7名中2番目), Hayashi, Y. (7名中5番目), Kakeya, H. (7名中6番目), Osada, H. (7名中7番目)
- Journal Title
  
  Biosci. Biotechnol. Biochem. 72
  
  Pages: 1894-1900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Fungal metabolite, epoxyquinol B, crosslinks proteins by epoxy-thiol conjugation.2008
- Author(s)
  Usui, T. (8名中2番目), Hayashi, Y. (8名中6番目), Kakeya, H. (8名中7番目), Osada, H. (8名中8番目)
- Journal Title
  
  J. Antibiot. 61
  
  Pages: 94-97
- NAID
  80019478123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Epoxyquinol B shows antiangiogenic effects by inhibiting not only VEGFR2 but also EGFR, FGFR, and PDGFR.2008
- Author(s)
  Kakeya, H. (7名中2番目), Usui, T. (7名中3番目), Hayashi, Y. (7名中6番目), Osada, H. (7名中7番目)
- Journal Title
  
  Oncol. Res. 17
  
  Pages: 11-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Fungal metabolite, epoxyquinol B crosslinks proteins by epoxyquinol-thiol conjugation.2008
- Author(s)
  H. Kamiyama, T. Usui, M. Uramoto, H. Takagi, M. Shoji, Y. Hayashi, H. Kakeya, H. Osada
- Journal Title
  
  J. Antibiot. 61
  
  Pages: 94-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein.2008
- Author(s)
  Kakeya, H. (15名中13番目), Osada, H. (15名中14番目)
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 4626-4651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Epoxyquinol B shows antiangiogenic effects in vitro and in vivo byinhibiting VEGFR, and EGFR, FGFR, and PDFR.2008
- Author(s)
  H. Kamiyama, H. Kakeya, T. Usui, K. Nishikawa, M. Shoji, Y. Hayashi, H. Osada
- Journal Title
  
  Oncol. Res.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Azaspirene, a fungal product, inhibits angiogenesis by blocking Raf-1 activation.2008
- Author(s)
  Kakeya, H. (8名中2番目), Kojima, S. (8名中4番目), Osada, H. (8名中8番目)
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 1853-1858
- NAID
  10024011306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] The asymmetric total synthesis of (+)-cytotrienin A, an ansamycin-type anticancer drug.2008
- Author(s)
  Hayashi, Y. (10名中1番目), Kakeya, H. (10名中9番目), Osada, H. (10名中10番目)
- Journal Title
  
  Angew. Chem. Int. Ed. 47
  
  Pages: 6657-6660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] 微生物が生産する新規生理活性物質の開拓とケミカルバイオロジー研究2007
- Author(s)
  掛谷秀昭
- Journal Title
  
  Jpn. J. Antibiot. 60
  
  Pages: 181-187
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] 微生物代謝産物由来の小分子ライブラリーの利用技術-スクリーニングとケミカルバイオロジー研究-2007
- Author(s)
  掛谷秀昭、齋藤安貴子、長田裕之
- Journal Title
  
  BIO INDUSTRY 24
  
  Pages: 48-54
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] A bridge between chemistry and biology2006
- Author(s)
  Kikuchi, K., Kakeya, H.
- Journal Title
  
  Nature Chem. Biol. 2
  
  Pages: 392-394
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] Epoxytwinol A, a novel unique angiogenesis inhibitor with C_2 symmetru, produced by a fungus.2005
- Author(s)
  H.Kakeya et al.
- Journal Title
  
  Chem. Commun. 2005
  
  Pages: 2575-2577
- Data Source
  KAKENHI-PROJECT-17GS0221
[Journal Article] Epoxytwinol A, a novel unique angiogenesis inhibitor with C_2 symmetry, produced by a fungus2005
- Author(s)
  Kakeya, H. et al.
- Journal Title
  
  Chem.Commun. 2005
  
  Pages: 2575-2577
- Data Source
  KAKENHI-PROJECT-16073223
[Journal Article] 血管内皮増殖因子(VEGF)の機能を標的とした新規血管新生阻害剤2004
- Author(s)
  掛谷秀昭
- Journal Title
  
  日本臨床 62
  
  Pages: 1264-1270
- Data Source
  KAKENHI-PROJECT-16073223
[Patent] 含窒素複素環式化合物2020
- Inventor(s)
  1)掛谷秀昭, 酒井麻利奈, 古谷　裕
- Industrial Property Rights Holder
  1)掛谷秀昭, 酒井麻利奈, 古谷　裕
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-209649
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19H02840
[Patent] 含窒素複素環式化合物2020
- Inventor(s)
  掛谷秀昭, 酒井麻利奈, 古谷　裕
- Industrial Property Rights Holder
  掛谷秀昭, 酒井麻利奈, 古谷　裕
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-209649
- Filing Date
  2020
- Data Source
  KAKENHI-PLANNED-17H06401
[Patent] 新規フルオロジニトロフェニル化合物及びその用途2019
- Inventor(s)
  掛谷秀昭、倉永健史、小川はるか
- Industrial Property Rights Holder
  掛谷秀昭、倉永健史、小川はるか
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research on microbes toward the development of novel antibiotics2022
- Author(s)
  Kakeya, H.
- Organizer
  Japan-the Netherlands Microbiology Symposium 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Syetematic screening of new microbial metabolites by combined-culture of actinomycetes2022
- Author(s)
  Watari, S., Kaneko, K., Iwata, S., Nagao, N., Onaka, H., Shinzato, N., Kakeya, H.
- Organizer
  Japan-the Netherlands Microbiology Symposium 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research on microbes toward the development of novel antibiotics2022
- Author(s)
  Kakeya, H.
- Organizer
  Japan-the Netherlands Microbiology Symposium 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] LC-MSを用いた中性条件下の好感度アミノ酸分析2021
- Author(s)
  森本涼太, 松元拓海, 箕手万由里, 柳沢将行, 山田竜太郎, 倉永健史, 掛谷秀昭
- Organizer
  創薬懇話会 2021
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] がん幹細胞を標的とした抗がん剤シーズ探索系の構築2021
- Author(s)
  池田拓慧, 川見美里, 井本正哉, 掛谷秀昭
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] ピラゾール骨格を有する新規低酸素誘導因子HIF-1阻害剤の開発研究2021
- Author(s)
  酒井麻利奈, 高橋伸明, 古谷　裕, 鈴木健裕, 堂前　直, 小林清香, 服部　明, 原田　浩, 掛谷秀昭
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research toward the development of new anticancer drugs2021
- Author(s)
  Kakeya, H.
- Organizer
  PACIFICHEM2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Discovery of longicatenamides A-D produced by combined-culture of Streptomyces sp. KUSC_F05 and Tsukamurella pulmonis TP-B05962021
- Author(s)
  Matsumoto, T., Jiang, Y., Kuranaga, T., Lu, S., Wang, W., Onaka, H. Kakeya, H.
- Organizer
  PACIFICHEM2021
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research toward the development of novel antibiotics2021
- Author(s)
  Kakeya, H.
- Organizer
  PACIFICHEM2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 微生物間化学コミュニケーションの理解・制御と有用生物活性リガンドの開発2021
- Author(s)
  掛谷秀昭, 倉永健史, 池田拓慧, 西村慎一, 井本正哉
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第8回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Curcumin mooglucuronide (CMG) treatment alters the gut microbiota, regulating an autoimmune model for multiple sclerosis2021
- Author(s)
  Omura, S., Khadka, S., Sato, F., Nakamura, Y., Nishio, K., Kakeya, H., Tsunoda, I.
- Organizer
  PACIFICHEM2021
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research toward the development of new anticancer drugs2021
- Author(s)
  Kakeya, H.
- Organizer
  PACIFICHEM2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Miclxin, a novel MIC60 inhibitor, induces apoptosis via mitochondrial stress in beta-catenin mutant tumor cells2021
- Author(s)
  Ikeda, H., Muroi, M., Kondoh, Y., Ishikawa, S., Kakeya, H., Osada, H., Imoto, M.
- Organizer
  PACIFICHEM2021
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] がん幹細胞を標的とした抗がん剤シーズの探索研究2021
- Author(s)
  池田拓慧, 川見美里, 井本正哉, 掛谷秀昭
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Design, synthesis , and application of highly sensitive labeling reagents inspired by a scarce natural product.2021
- Author(s)
  Minote, M., Kuranaga, T., Morimoto, R., Pan, C., Ogawa, H., Kakeya, H.
- Organizer
  PACIFICHEM2021
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] LC-MSを用いた中性条件下の好感度アミノ酸分析2021
- Author(s)
  森本涼太, 松元拓海, 箕手万由里, 柳沢将行, 山田竜太郎, 倉永健史, 掛谷秀昭
- Organizer
  創薬懇話会 2020
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical communication research toward the development of novel antibiotics2021
- Author(s)
  Kakeya, H.
- Organizer
  PACIFICHEM2021
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Highly sensitive amino acid labeling reagents inspired by a scarce natural product yaku'amide B2021
- Author(s)
  Kuranaga, T., Minote, M., Morimoto, R., Pan, C., Ogawa, H., Kakeya, H.
- Organizer
  PACIFICHEM2021
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] がん幹細胞を標的とした抗がん剤シーズの探索研究2021
- Author(s)
  池田拓慧, 川見美里, 井本正哉, 掛谷秀昭.
- Organizer
  日本ケミカルバイオロジー学会　第15回年会
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 放線菌由来ロンギカテナミドA-Dに関する研究：異属微生物の複合培養による生産、構造決定、生物活性、及び全合成2021
- Author(s)
  松元拓海, Yulu Jiang, 倉永健史 Shun Lu, Weicheng Wang, 尾仲宏康, 掛谷秀昭
- Organizer
  第63回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 放線菌由来ロンギカテナミドA-Dに関する研究：異属微生物の複合培養による生産、構造決定、生物活性、及び全合成2021
- Author(s)
  松元拓海, Yulu Jiang, 倉永健史 Shun Lu, Weicheng Wang, 尾仲宏康, 掛谷秀昭
- Organizer
  第63回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] ピラゾール骨格を有する新規低酸素誘導因子HIF-1阻害剤の開発研究2021
- Author(s)
  酒井麻利奈, 高橋伸明, 古谷　裕, 鈴木健裕, 堂前　直, 小林清香, 服部　明, 原田　浩, 掛谷秀昭
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 自然に学ぶ生理化学研究：分子プローブ開発と創薬2020
- Author(s)
  掛谷秀昭
- Organizer
  京都大学学際融合教育推進センター・生理化学研究ユニット第10回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Discoveryof sulfur-containing cyclic lipopeptides thioamycolamides A-E, producedby the rare ctinomycete Amycolatopsis sp.2020
- Author(s)
  Pan, C., Kuranaga, T., Liu, C., Lu, S., Shinzato, N., Kakeya, H
- Organizer
  The 62nd Symposium on the Chemistry of Natural Products
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 希少天然物の構造をモチーフとした高感度ラベル化剤の開発2020
- Author(s)
  箕手万由里, 小川はるか, 森本涼太, 潘承謙, 倉永健史, 掛谷秀昭
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] アカデミア発創薬を目指した創薬ケミカルバイオロジー研究2020
- Author(s)
  掛谷秀昭
- Organizer
  TSMTP (Translational Science and MedicineTraining Program) Symposium in Sapporo
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 有用生物活性リガンドの開発を志向した化学コミュニケーション研究2020
- Author(s)
  掛谷秀昭
- Organizer
  有機合成のニュートレンド2020（有機合成化学協会関西支部主催）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Continuing Fascination with Discovery Science: Phenotypic Screening to Chemical Biology.2020
- Author(s)
  Kakeya, H.
- Organizer
  Mona Symposium 2020: Natural Product Chemistry and Medicinal Chemistry.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Discovery of sulfur-containing cyclic lipopeptides thioamycolamides A-E, producedby the rare ctinomycete Amycolatopsis sp.2020
- Author(s)
  Pan, C., Kuranaga, T., Liu, C., Lu, S., Shinzato, N., Kakeya, H
- Organizer
  The 62nd Symposium on the Chemistry of Natural Products
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Continuing Fascination with Discovery Science: Phenotypic Screening to Chemical Biology2020
- Author(s)
  Kakeya, H.
- Organizer
  Mona Symposium 2020: Natural Product Chemistry and Medicinal Chemistry
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 自然に学ぶ生理化学研究：分子プローブ開発と創薬2020
- Author(s)
  掛谷秀昭
- Organizer
  京都大学学際融合教育推進センター・生理化学研究ユニット第10回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 微生物間化学コミュニケーションの理解と有用生物活性リガンドの開発2019
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第6回公開シンポジウム.
- Invited
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Developmentof an injectable water-soluble anticancer drug CMG for oxaliplatin-resistantcolorectal cancer with KRAS mutation2019
- Author(s)
  Kakeya, H, Kishimoto, A., Umeta, H., Imaizumi, A., Kanai, M.
- Organizer
  31th EORTC-NCI-AACR Symposium: InternationalConference on Molecular Targets and Cancer Therapeutics
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Highly sensitive labeling reagents inspired by a scarce marine natural product.2019
- Author(s)
  Kuranaga, T., Kakeya, H.
- Organizer
  10th Korea-Japan Chemical Biology Symposium.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 低酸素誘導因子HIF-1阻害活性を有する環状デプシペプチドverucopeptinの全合成2019
- Author(s)
  高橋伸明, 林　秀明, Poznaks, V. 掛谷秀昭
- Organizer
  第61回天然有機化合物討論会
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬の復権を期して：微生物間化学コミュニケーションの利活用2019
- Author(s)
  掛谷秀昭
- Organizer
  第402回CBI学会（情報計算化学生物学会）講演会（東京）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Highly sensitive labeling reagents inspired bya scarce marine natural product2019
- Author(s)
  Kuranaga, T., Kakeya, H.
- Organizer
  10th Korea-Japan Chemical Biology Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 自然に学ぶ薬づくり2019
- Author(s)
  掛谷秀昭, 倉永健史
- Organizer
  京都大学アカデミックデイ2019
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical comunication research toward the development of usefulchemical probes2019
- Author(s)
  Kakeya, H.
- Organizer
  The 4th A3 Roundtable Meeting on Asia Chemical Probe Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 有用生物活性リガンドの開発を志向した化学コミュニケーション研究2019
- Author(s)
  掛谷秀昭
- Organizer
  有機合成のニュートレンド2020（有機合成化学協会関西支部主催）
- Invited
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Natural products-prompted chemical biology: Phenotypic screening and a new platform for target identification.2019
- Author(s)
  Kakeya, H.
- Organizer
  The 6th Tishler-Omura Sympoium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] 化学コミュニケーションが織りなす生命科学2019
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第99春季年会（2019）
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Frontier research on chemical communications unveils the mysteryof life science2019
- Author(s)
  Kakeya, H.
- Organizer
  The 27th International Society of Heterocyclic ChemistryCongress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの利活用による新規有用生物活性リガンドの開発研究2019
- Author(s)
  掛谷秀昭
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Development of cryptic antifungal 5aTHQs targting cell membranesignaling2019
- Author(s)
  Hideaki Kakeya
- Organizer
  Asian Chemical Biology Initiative (ACBI) 2019 Yangon Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Natural products-prompted chemical biology: Phenotypic screeningand a new platform for target identification2019
- Author(s)
  Kakeya, H.
- Organizer
  The 6th Tishler-Omura Sympoium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Chemical comunication research toward the development of useful chemical probes.2019
- Author(s)
  Kakeya, H.
- Organizer
  The 4th A3 Roundtable Meeting on Asia Chemical Probe Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02840
[Presentation] Developmentof an innovative water-soluble anticancer drug, curcumin mono-beta-D-glucuronide(CMG)2019
- Author(s)
  Hideaki Kakeya, Nobuaki Takahashi, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 低酸素応答シグナルを標的とした創薬ケミカルバイオロジー2019
- Author(s)
  掛谷秀昭
- Organizer
  日本薬学会第139年会（千葉）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「シンポジウム・がんと宿主の化学コミュニケーションの理解と制御」. 水溶性プロドラッグ型分子標的抗がん剤CMGの開発研究2019
- Author(s)
  掛谷秀昭
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Development of cryptic antifungal 5aTHQs targeting cell membranesignaling2019
- Author(s)
  Hideaki Kakeya
- Organizer
  Asian Chemical Biology Initiative (ACBI) 2019 Yangon Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 化学コミュニケーションが織りなす生命科学2019
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第99春季年会（2019, 神戸）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Symposia20 "Frontier in Molecular Target Therapy of Cancer": Developmentof a water-soluble prodrug CMG which inhibits proteasome activity throughDYRK2 dependent manner.2019
- Author(s)
  Kanai, M., Kishimoto, A., Umeta, H., Imaizumi, A., Kakeya, H.
- Organizer
  The 78th Annual Meeting of the Japanese CancerAssociation
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Towards thedevelopment of chemical communication molecules among microbes.2019
- Author(s)
  Yulu Jiang, Shan Lu, Go Hirai, Taira Kato, Hiroyasu Onaka, Hideaki Kakeya
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの理解と有用生物活性リガンドの開発2019
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第6回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの利活用による新規生物活性リガンドの開発研究2019
- Author(s)
  掛谷秀昭
- Organizer
  第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジー2018
- Author(s)
  掛谷秀昭, 野中元裕, 倉永健史
- Organizer
  京都大学アカデミックデイ2018
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Microbial metabolites targeting microenvironment: a cell membranesigaling modulator and a hypoxia-response modulator2018
- Author(s)
  Hideaki Kakeya
- Organizer
  The 9th Japan-Koreachemical biology symposium (Inchon, Korea)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「シンポジウム：これからの天然物サイエンス」―ケミカルスペース拡充戦略：微生物複合培養法及びPDSS (Precurso-Directed in situ Synthesis)法―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2018年度大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 医薬品シード分子の多様性創出と細胞内標的探索・同定2018
- Author(s)
  掛谷秀昭
- Organizer
  京大テックフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Expansion of chemical space in saccharothriolides: Precursor-directed in situ synthesis (PDSS) in a rare actinomycete Saccharothrix sp.2018
- Author(s)
  Shan Lu, Shinichi Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Organizer
  Natural Product Discovey & Development in the Genomic Era (Natural Products 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 天然物創薬ケミカルバイオロジー～放線菌に魅せられて～2018
- Author(s)
  掛谷秀昭
- Organizer
  2018年度（第33回）日本放線菌学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Microbial metabolites targeting microenvironment: a cell membranesigaling modulator and a hypoxia-response modulator2018
- Author(s)
  Hideaki Kakeya
- Organizer
  The 9th Japan-Koreachemical biology symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] アポトーシス誘導活性天然物cytotrieninAの合成研究2018
- Author(s)
  岩渕好治, 佐藤亮, 笹野裕介, 小松慎吾, 野口正嗣, 掛谷秀昭, 長田裕之, 叶直樹
- Organizer
  第60回天然有機化合物討論会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「中長期企画・ケミカルバイオロジー研究加速のための生物活性分子の発見戦略」―微生物間化学コミュニケーションの謎に挑む―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本化学会第98春季年会（2018）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジーの醍醐味2018
- Author(s)
  掛谷秀昭
- Organizer
  第53回天然物化学談話会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] Drug delivery to malignant brain tumorby a peptide specific to Annexin A12018
- Author(s)
  Motohiro Nonaka, Hideaki Kakeya, Michiko Fukuda.
- Organizer
  30th EORTC-NCI-AACRSymposium: International Conference on Molecular Targets and Cancer Therapeutics (Dublin)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの利活用によるケミカルスペース拡充戦略2018
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第2回公開シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Expansion of chemical space in saccharothriolides: Precursor-directed in situ synthesis (PDSS) in a rare actinomycete Saccharothrix sp2018
- Author(s)
  Shan Lu, Shinichi Nishimura, Masashi Ito, Taira Kato, Hideaki Kakeya
- Organizer
  Natural Product Discovey & Development in the Genomic Era (Natural Products 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Rapid screening of antibody-bindingpeptides by combination of T7 phage display and next-generation sequencingtechnologies2018
- Author(s)
  Motohiro Nonaka, Michiko Fukuda, Hideaki Kakeya
- Organizer
  The 1st International Symposium on Chemical Communication (ISCC2019, Tokyo)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 天然物創薬ケミカルバイオロジーの醍醐味2018
- Author(s)
  掛谷秀昭
- Organizer
  第53回天然物化学談話会（大阪）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物の複合培養で得られる5aTHQの膜親和性と生物活性. 第60回天然有機化合物討論会2018
- Author(s)
  西村慎一, 杉山龍介, 仲谷崇宏, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  第60回天然有機化合物討論会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 医薬品シード分子の多様性創出と細胞内標的探索・同定2018
- Author(s)
  掛谷秀昭
- Organizer
  京大テックフォーラム（東京）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「化学コミュニケーションのフロンティア」を起点にした創薬ケミカルバイオロジー2018
- Author(s)
  掛谷秀昭
- Organizer
  新学術領域研究「脂質クオリティが解き明かす生命現象」第4回領域会議
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 微生物間化学コミュニケーションの理解と有用生物活性リガンドの開発2018
- Author(s)
  掛谷秀昭, 西村慎一, 倉永健史, 野中元裕, 井本正哉
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」・第3回公開シンポジウム（東京）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Development of a syntheticwater-soluble curcumin mono-beta-D-glucuronide (CMG), as an innovativeanticancer prodrug targeting KRAS-NF-kappaB signaling pathway2018
- Author(s)
  Hideaki Kakeya, Atsuhiro Kishimoto, Atsushi Imaizumi, Masashi Kanai
- Organizer
  30th EORTC-NCI-AACRSymposium: International Conference on Molecular Targets and Cancer Therapeutics (Dublin)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 多隔壁形成や細胞伸長におけるスフィンゴ脂質の重要性2018
- Author(s)
  生田実沙, 伊藤愛理, 西村慎一, 吉田稔, 掛谷秀昭
- Organizer
  酵母遺伝学フォーーラム第51回研究報告会（福岡）
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] Development of a water-soluble curcuminmonoglucronide (CMG) as a novel anticancer prodrug targeting KRAS-NF-kappaB signaling pathway2018
- Author(s)
  Kanai, M., Imaizumi, A., Kakeya, H
- Organizer
  Global Academic Programs (GAP) conference (Stockholm, Sweden)
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 「シンポジウム：これからの天然物サイエンス」―ケミカルスペース拡充戦略：微生物複合培養法及びPDSS (Precurso-Directed in situ Synthesis)法―2018
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2018年度大会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19233
[Presentation] 新しい抗真菌薬シード開発と適応拡大戦略」―抗真菌薬開発のためのケミカルバイオロジー研究方略：シード分子開発とメカニズム解析2017
- Author(s)
  掛谷秀昭
- Organizer
  技術情報協会セミナー
- Place of Presentation
  東京
- Year and Date
  2017-08-02
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 創農薬イノベーションを創発するケミカルバイオロジー方略2017
- Author(s)
  掛谷秀昭
- Organizer
  農薬デザイン研究会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 機能性食品素材の医薬品への展開を目指した創薬ケミカルバイオロジー2017
- Author(s)
  今泉厚, 高橋伸明, 光金英宣, 金井雅史, 橋本正, 牧野悠治, 津田孝範, 掛谷秀昭
- Organizer
  第7回食品薬学シンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-17H06401
[Presentation] 創薬ケミカルバイオロジー研究方略：表現型スクリーニングとシード分子開発2017
- Author(s)
  掛谷秀昭
- Organizer
  ビッグデータ駆動型創薬システム研究拠点・第3回シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] アカデミア創薬における表現型スクリーニングと次世代天然物化学2017
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都
- Year and Date
  2017-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] Microbial metabolites-prompted chemical biology: Phenotypic screening and a new platform for target identification2016
- Author(s)
  Kakeya, H
- Organizer
  The Fifth Symposium of RIKEN-Max Planck Joint Research Center for System Chemical Biology
- Place of Presentation
  Germany
- Year and Date
  2016-04-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 脂質結合性天然物の活用―放線菌複合培養液より見出した新規アルカロイド群に関する研究2016
- Author(s)
  杉山龍介, 西村慎一, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 微生物の複合培養で得られる5aTHQとstreptoaminalの構造と構造2016
- Author(s)
  西村慎一, 杉山龍介, 仲谷崇宏, 尾崎太郎, 浅水俊平, 尾仲宏康, 掛谷秀昭
- Organizer
  第21回天然薬物の開発と応用シンポジウム
- Place of Presentation
  千葉
- Year and Date
  2016-10-27
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] 5-Alkyl-1,2,3,4-tetrahydroquinolines (5aTHQs), new membrane-interacting lipophilic metabolites, produced by combined-culture of Streptomyces nigrescens and Tsukamurella pulmonis2015
- Author(s)
  Sugiyama, R., Nishimura, S., Ozaki, T., Asamizu, S., Onaka, H., Kakeya, H.
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] Natural products-prompted chemical biology; Phenotypic screening and target identification2015
- Author(s)
  Kakeya, H.
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (PACIFICHEM 2015)
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] シンポジウム「創薬の将来」. 創薬ケミカルバイオロジー：シード分子開発と分子プロファイリング2015
- Author(s)
  掛谷秀昭
- Organizer
  第63回日本化学療法学会総会
- Place of Presentation
  東京
- Year and Date
  2015-06-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K14721
[Presentation] がん分子標的創薬を指向した低酸素誘導因子(HIF)阻害剤の探索・開発研究2014
- Author(s)
  嶋田清香、吉村彩、安田順信、高橋伸明、西村慎一、服部明、掛谷秀昭
- Organizer
  文科省新学術領域研究・がん支援「化学療法基盤支援活動」第三回シンポジウムアカデミアからの抗がん剤創薬に向けて-天然物の有効利用
- Place of Presentation
  万国津梁館(沖縄県・名護市)
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] Chemical biology for drug discovery and target identification2014
- Author(s)
  掛谷秀昭
- Organizer
  IUPAC2014 & 248th ACS National Meeting
- Place of Presentation
  San Francisco, U.S.A.
- Year and Date
  2014-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] "ものとり"・"ものづくり"を基盤としたケミカルバイオロジー研究2012
- Author(s)
  掛谷秀昭
- Organizer
  日本農芸化学会2011年度大会シンポジウム「食品機能学と薬理学:接点と相違点から学ぶ次のアプローチ」
- Place of Presentation
  京都(招待講演)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 天然物化学を基盤とした創薬ケミカルバイオロジー2012
- Author(s)
  掛谷秀昭
- Organizer
  若手研究者のための有機化学札幌セミナー
- Place of Presentation
  北海道
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 低酸素誘導因子(HIF)の機能制御物質の探索・評価2011
- Author(s)
  掛谷秀昭
- Organizer
  シンポジウムがん支援活動「化学療法基盤支援活動」-アカデミアからの抗がん剤創薬へ向けて
- Place of Presentation
  京都(招待講演)
- Year and Date
  2011-03-09
- Data Source
  KAKENHI-PROJECT-221S0001
[Presentation] 微生物代謝産物由来の新規バイオプローブの探索とケミカルバイオロジー研究2008
- Author(s)
  掛谷秀昭、長田裕之
- Organizer
  第4回ケミカルバイオロジーシンポジウム-化学-生物融合領域創成の軌跡-
- Place of Presentation
  静岡
- Year and Date
  2008-02-07
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] 微生物潜在能力の再認識-創薬と基礎研究への応用2008
- Author(s)
  掛谷秀昭, 他
- Organizer
  第17回天然薬物の開発と応用シンポジウム
- Place of Presentation
  九州大学(福岡)
- Data Source
  KAKENHI-PROJECT-17GS0221
[Presentation] "ものとり"を基盤としたケミカルバイオロジー研究.第128回日本薬学会シンポジウム天然物パワー:『ものとり,合成,機能解明』〜大学発天然物薬学研究〜2008
- Author(s)
  掛谷秀昭
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] 有用天然有機化合物の開拓とケミカルバイオロジー研究2007
- Author(s)
  掛谷秀昭
- Organizer
  有機合成化学協会講習会(平成19年度後期(秋))
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] Epoxyquinol B inhibits the NF-kB signaltransduction pathway through the TAK1 activity.2007
- Author(s)
  神山洋, 掛谷秀昭, 臼井健郎, 櫻井宏明, 長田裕之
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] Aspergillus fumigatusの生産する細胞周期阻害剤トリプロスタチンの生合成遺伝子クラスターの同定2007
- Author(s)
  加藤直樹、高木海、浅見行弘、掛谷秀昭、長田裕之
- Organizer
  第2回日本ケミカルバイオロジー研究会
- Place of Presentation
  京都
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] Panepophenatnrinの不斉全合成及びその構造活性相関研究2007
- Author(s)
  掛谷秀昭, 松澤正芳, 山口潤一郎, 庄司満, 掛谷秀昭, 小野瀬利恵, 長田裕之
- Organizer
  第49回天然有機化合物討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-16073223
[Presentation] HTLV-I感染細胞および上皮系腫瘍細胞においてユビキチン化修飾酵素A20はcaspase-8抑制因子として機能する
- Author(s)
  斉藤愛記、持田佳奈子、鶴山惠理、市川裕菜、大友悠太郎、掛谷綾香、深澤麻純、宇野雅哉、徳永文稔、宇都宮與、渡邉俊樹、山岡昇司
- Organizer
  新学術領域研究「修飾シグナル病」若手ワークショップ
- Place of Presentation
  ホテルあかね(神奈川県・足柄下郡湯河原町)
- Year and Date
  2014-09-30 – 2014-10-02
- Data Source
  KAKENHI-PROJECT-221S0001

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# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
185. ISHIKAWA Fumihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
186. MORIMOTO Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
187. SUNAGAWA Yoichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
188. OMURA Seiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
189. 尾仲宏康

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
190. 長谷川浩二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
191. 服部明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
192. 岩渕好治

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
193. 松森信明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
194. 片岡孝夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
195. 井貫晋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
196. 渡辺能行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
197. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
198. 原田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
199. 浅水俊平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
200. 倉永健史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
201. 室井誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kakeya Hideaki 掛谷 秀昭

KAKEYA Hideaki 掛谷 秀昭

掛合 秀昭 カケヤ ヒデアキ

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Development of scarce natural products and innovative anticancer seedsPrincipal Investigator

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Frontier research on chemical communicationsPrincipal Investigator

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Chemical biology on a bioactive substance regulating the hypoxia response signalPrincipal Investigator

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Biosynthetic research on cryptic gene activationPrincipal Investigator

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Chemical communications in microbial interactions and development of useful bioactive ligandsPrincipal Investigator

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Frontier research of chemical communicationsArea Organizer

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Frontiers in Chemical CommunicationsPrincipal Investigator

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Chemical biology on cryptic genes activationPrincipal Investigator

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微生物代謝産物由来の機能性天然分子の探索・創製と応用研究Principal Investigator

Kakeya Hideaki 掛谷秀昭

KAKEYA Hideaki 掛谷秀昭

掛合秀昭カケヤヒデアキ

[Book] くすりの科学知識-今こそ知っておきたいくすりの効能、しくみ、正しい付き合い方-（増補第3版）2021

[Book] くすりの科学知識-今こそ知っておきたいくすりの効能、しくみ、正しい付き合い方-（増補第3版）2021