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Yamamoto Masayuki  山本 雅之

… Alternative Names

YAMAMOTO Masayuki  山本 雅之

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Researcher Number 50166823
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9073-9436
External Links
Affiliation (Current) 2025: 東北大学, 東北メディカル・メガバンク機構, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東北大学, 東北メディカル・メガバンク機構, 教授
2016 – 2022: 東北大学, 医学系研究科, 教授
2015 – 2016: 東北大学, 大学院医学系研究科, 教授
2012 – 2015: 東北大学, 医学(系)研究科(研究院), 教授
2011: 東北大学, 医学研究科, 教授 … More
2010 – 2011: 東北大学, 医学系研究科, 教授
2007 – 2011: Tohoku University, 大学院・医学系研究科, 教授
2009: 東北大学, 医学系研究科
2006: 筑波大, 人間総合科学研究科, 教授
2006: University of Tsukuba, Graduate school of Comprehensive human sciences, Professor, 大学院人間総合科学研究科, 教授
2006: 筑疲大学, 大学院・入間総合科学研究科, 教授
2005: 筑波大学, 人間総合科学研究科, 教授
2005: 筑波大学, 基礎医学系先端学際領域研究センター, 教授
2004 – 2005: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Professor, 大学院・人間総合科学研究科, 教授
2004: 筑波大学, 基礎医学系学際領域研究センター, 教授
1995 – 2004: 筑波大学, 基礎医学系, 教授
2003: University of Tsukuba, Institute of Basic Medical Sciences and Center for Tsukuba Advanced Research Alliance, Professor, 基礎医学系(先端学際領域研究センター), 教授
2002 – 2003: 筑波大学, 基礎医学系先端学際領域研究センター, 教授
2001 – 2002: 筑波大学, 先端領域学際センター, 教授
2000 – 2002: 筑波大学, 基礎医学系・先端学際領域研究センター, 教授
2001: 筑波大学, 基礎医学系(先端学際領域研究センター), 教授
2001: 筑波大学, 基礎医学系先端学際領域センター, 教授
1998 – 2001: 筑波大学, TARAセンター, 教授
1999: 筑波大学, 基礎医学系最先端学際領域研究センタ, 教授
1999: Tohoku University, Graduate School of Medicine, Professor
1998 – 1999: 筑波大学, 基礎医学系先端学際領域研究センター, 教授
1995 – 1998: 筑波大学, 先端学際, 教授
1997: 筑波大学, 先端学際領域研究センター, 教授
1995: 筑波大学, 基礎医学系 先端学際領域研究センター, 教授
1991 – 1994: 東北大学, 医学部, 講師
1993: 東北大学, 医学部, 助手
1987 – 1988: 富山医科薬科大学, 医学部, 助教授 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / General medical chemistry / Pathological medical chemistry / General medical chemistry / Molecular biology / Biological Sciences / Medium-sized Section 48:Biomedical structure and function and related fields / Medium-sized Section 50:Oncology and related fields / Broad Section H / Hematology / Biological Sciences / Developmental biology … More
Except Principal Investigator
… More Pathological medical chemistry / General medical chemistry / Applied veterinary science / Biological Sciences / Biological Sciences / Molecular biology / Digestive surgery / Pathological medical chemistry / General medical chemistry / Hematology / Transformative Research Areas, Section (III) / Risk sciences of radiation and chemicals / Hematology / Applied veterinary science / Surgical dentistry / Environmental pharmacy / Functional biochemistry / Hygiene / Human pathology / Eating habits, studies on eating habits / Clinical veterinary science / Digestive surgery Less
Keywords
Principal Investigator
転写因子 / 転写制御 / 赤血球 / GATA-2 / GATA-1 / 細胞分化 / 酸化ストレス / Nrf2 / 白血病 / トランスジェニックマウス … More / NF-E2 / Keap1 / 造血幹細胞 / bZip型転写因子 / 遺伝子発現制御 / GATA転写因子 / EVI1 / 遺伝子改変マウス / モデル動物 / 環境異物 / 異物代謝 / 赤血球分化 / Maf / GATA因子群 / ストレス応答 / bHLH-PAS型転写因子 / ゼブラフィッシュ / 遺伝子破壊マウス / c-Maf / differentiation / transcription factor / GATA転写因子群 / GATA2 / 染色体転座 / 造血 / 炎症 / ストレス / 環境 / 発現制御 / エリスロポエチン / 低酸素 / ダウン症候群 / 白血病幹細胞 / 個体発生 / 親電子性物質 / CNCファミリー / 遺伝子部分破壊マウス / 巨核球 / セルトリ細胞 / 遺伝子 / 食道がん / 前がん細胞 / NRF2 / がん悪性化 / KEAP1-NRF2系 / 健康長寿 / 加齢関連疾患 / Keap1-Nrf2制御系 / 逆位 / エンハンサー / 転座 / Z-form DNA / Chromatin remodeling / Transcription regulation / Stress / Signal transduction / Environment / 化学発がん / 血病 / 発がん防御 / Z-DNA / クロマチン構造変換 / シグナル伝達 / Bone marrow transplantation / GATA-2 conditional knock-out mouse / GFP knock-in mouse in the GATA-2 locus / Hematopoietic stem cell / ヘマンジオブラスト / 緑色蛍光蛋白質 / 骨髄移植 / 条件付きノックアウトマウス / GFPノックインマウス / Down syndrome / Leukemia / Myelodysplastic syndrome / Erythroid differentiation / Apoptosis / GATA-1 knockdown mouse / 骨髄異型性症候群 / アポトーシス / GATA-1ノックダウンマウス / bHLH-PAS TRANSCRIPTION FACTORS / bZip TRANSCRIPTION FACTORS / MODEL ANIMALS / TRANSCRIPTIONAL REGULATION / XENOBIOTICS / DETOXIFICATION / b-Zip型転写因子 / zebrafish / mouse / oxidative stress / chemicals / transcriptional regulation / xenobiotics / electrophiles / マウス / バイオモニター / gene regulatory network / neurodegeneration / megakaryocytes / transcription / gene targeting / bZip transcription factors / 神経変性症 / 遺伝子制御ネットワーク / 神経変性 / autoimmune disease / T lymphocyte / transgenic mouse / C-Maf / Tリンパ球 / 自己免疫疾患 / 疾患感受性 / T細胞 / C.Maf / genetargeting / hematopoietic stem cells / erythroid cells / 転写因子ネットワーク / 蛋白質間相互作用 / プロモーター破壊 / 遺伝子破壊 / CNC転写因子群 / 血球細胞分化 / ジーンターゲティング / 血造幹細胞 / NF・E2 / Hematopoietic Stem Cell / CNC family / Cell differentiation / Red Blood Cells / Transcription factor / NGF-E2 / GATA因子部 / NF-EZ / Sertoli cells / Testis / Cell defferentiation / Erythroid cells / GATA factors / 遺伝子構造解析 / 精巣 / 染色体逆位 / 腎臓病 / 貧血 / 酸化ストレス応答 / 低酸素応答 / 分子腫瘍学 / がん / オートファジー / 病態代謝 / 神経変性疾患 / 転写制御機構 / Nrf1 / 環境応答 / 血液学 / 遺伝子発現 / 発生・分化 / Keap1造血 / 量的異常 / 質的異常 / 前赤芽球性性白血病 / 一過性骨髄増殖症 / 巨核芽球白血病 / 治療抵抗性 / 幹細胞性 / GATA1 / 多段階発がん / 癌抑制 / 発癌 / c-Kit陽性骨髄造血前駆細胞 / マイクロアレイ法 / OP9ストローマ細胞 / 細胞分化方向性 / 胎児造血幹細胞 / 自己複製能維持 / クロヌチン / 基本転写因子 / 転写 / GATA因子 / プロテオソーム / 蛋白質分解 / b-ZIP構造 / 形質転換 / bZip構造 / 小Maf群タンパク質 / ヘムオキシゲナーゼ / グルタチオンS-トランスフェラーゼ / ノックアウトマウス / ジーンターゲディング / プロモーター / 生殖細胞 / 細胞特異的遺伝子発現 / NF‐EZ / 遺伝子解析 / T細胞受容体 … More
Except Principal Investigator
転写因子 / Nrf2 / GATA-1 / GATA / NF-E2 / 赤血球 / シグナル伝達 / 遺伝子 / 細胞分化 / ノックアウトマウス / トランスジェニックマウス / 鉄芽球性貧血 / 赤血球分化 / 酸化ストレス / 転写調節 / 転写制御 / 牛 / 遺伝子改変マウス / バンド3 / プロモーター / 標的遺伝子 / erythropoietin / GATA-2 / δ-アミノレブリン酸合成酵素 / 糖尿病 / イメージング / 肝発癌 / 脂肪性肝炎 / 生活習慣病 / 赤血球膜 / 膜骨格 / 癌 / アポトーシス / 造血幹細胞 / エリスロポエチン / エンハンサー / 遺伝子発現 / 癌遺伝子 / 遺伝子レスキューマウス / 肝癌 / 肥満 / Keap1 / 膵β細胞 / VEGF / HIF / AHSP / benzo[a]pyrene / Gene expression / GATA inhibitor / Cadmium / L-arginine / L-NMMA / HIF-1 / gene expression / Erythropoietin / promoter / NGF / CRE / ARE / thioredoxin / transgenic mouse / FGF4 / BTEB2 / BTEB / cattle / ankyrin / band 3 / membrane skeleton / 小胞輸送 / アンキリン / GFP / トランスジェニック / MSP23 / Prx I / A170 / HO-1 / Transgenic mice / Hematopoiesis / target genes / transcription factor / 発生 / Bach / NF-E2p45 / 巨核球 / in situ hybridization / GATA-3 / ヘム / p18 / 造血前駆細胞 / CD34 / signal transduction / ヘム代謝 / ヘム生合成 / 低酸素 / 酸素生物学 / 細胞シグナル / 活性酸素種 / 酸素 / 遺伝性疾患 / 小胞体 / 細胞・組織 / 小Maf群因子 / 血球分化 / ゲノム / 幹細胞 / 血液細胞 / GATA転写因子 / 白血病 / maf / ダイオキシン / 転写伸長 / コアクチベータ- / 5-アミノレブリン酸合成酵素 / c-maf / 骨髄性プロトポルフィリン症 / フェロキラターゼ / c-kit / Myb / KEAP1 / レドックス / 酸性化 / リソソーム / システインプロテアーゼ / セレン / セレノプロテインP / 還元ストレス / 抗酸化システム / NRF2 / セレノプロテイン / 細胞・組織 / 環境 / Mrf2 / 環境応答 / 活性酸素 / 遺伝子組換えマウス / DNA損傷 / 突然変異 / MIS応答 / 皮膚 / 紫外線 / 肥満関連肝疾患 / 病態生理 / 腸内細菌 / 非アルコール性脂肪性肝疾患 / 臓器レスキューマウス / 視床下部 / レプチン抵抗性 / インスリン抵抗性 / 代謝学 / セレノシステイン / 腎性尿崩症 / 生体分子 / 遺伝子改変 / センサー / glycine cleavage system / H-protein cDNA / glycine decarboxylase cDNA / coupled expression of the genes / 高グリシン血症 / H-蛋白遺伝子 / グリシン脱炭酸酵素遺伝子 / 鶏ゲノムDNAライブラリー / H-蛋白cDNA / 遺伝子の臓器特異的発現調節 / Hー蛋白cDNA / グリシン脱炭酸酵素cDNA / グリシン開裂系 / 複数遺伝子の協調的発現 / enhancer / 血管形成 / 2-oxoglutarate / vascular endothelial growth factor / K-11706 / hypoxia inducible factor-1 / 酸素センサー / エリストポエチン / zoonosis / transcription regulation / cytokine / hematopoietic precursor cells / molecular diagnosis / prion diseases / PrPc(cellular prion protein) / 人獣共通感染症 / サイトカイン / 分子診断 / プリオン病 / gene trapping / knockout mouse / Peroxiredoxin / ジーントラップ / ペルオキシレドキシン / cell culture / intracellular vesicles / membrane trafficking / red blood cell / erythroid development / スペクトリン / 膜骨格タンパク質 / 赤芽球系分化 / 培養細胞 / 赤芽球分化 / in vivo mutagenesis / nitropyrene / diesel exhaust / gpt delta mouse / mutagen / Benzo(a)pyrene / 1,6-ジニトロピレン / 変異物質検出 / Nrf2ノックアウトマウス / 変異原物質検出 / 体内突然変異 / 遺伝子導入マウス / ニトロピレン / ベンゾ[a]ピレン / ディーゼル排気 / gpt deltaマウス / 変異原物質 / Hydrogen peroxide / Oxidative stress / ヘミン / 神経突起伸長 / NFG / 3-methylcholanthrene / subtraction / transcription / proplatelet formation / megakaryocytes / small Maf proteins / サブトラクション / 胞体突起形成 / hippocampus / cerebellum / gene-knockout mice / GCbox consensus sequence / targeting vectors / T_3 / β-gal / in vitro / ホモ欠失マウス / ターゲッティングペクター / 海馬 / 小脳 / 遺伝子欠失マウス / GCbox配列 / ターゲティングベクター / dioxins / toxicological assessment / bioassay system / genetically altered mice / toxic chemicals / 環境リスク / ダイオキシン類 / 毒性評価 / バイオアッセイ / 遺伝子改変動物 / 有害化学物質 / vesicle trafficking / proeasome / congenital hemolytic anemia / red cell membranes / 遺伝性バンド3欠損症 / 膜移行 / 膜蛋白質 / プロテアソーム / 遺伝性溶血性貧 / プロテアゾーム / 遺伝性溶血性貧血 / Positive autoregulation / Transgenic fish / Transcriptional Regulation / Erythropoiesis / Zebrafish / 橋渡し分子 / GTAT-1 / 正のフィードバック機構 / トランスジェニックフィッシュ / ゼブラフィッシュ / Gene tragetting / Transcription factors / CATA transcription factors / ジーンターゲティング / GATA因子群 / LDL / 酸化LDL / PrxI / Knockout mice / Erythroid cells / Heme / モデル動物 / 環状鉄芽球 / 鉄代謝 / 赤血球系細胞 / Inberited disorders / Band 3 / Enhancers / Promoters / transcription factors / Gene therapy / 家畜 / 赤芽球系造血 / 遺伝子治療 / Transcription factor / Autoimmune disease / T lymphocyte / Transgenic mouse / c-Maf / 自己免疫疾患 / Th2 / Th1 / neuronal system / hematopoietic system / development / transcriptional mediators / mutant mice / transcriptional regulator / transcriptional control / 分化 / 神経系 / 造血系 / 転写仲介因子 / 変異マウス / 制御因子 / stem cells / transcription elongation / transcription initiation / functional echanism / inter-transcriptional interaction / transcriptional cofactor / 形態形成 / 中間報告 / 共同研究 / 冬のワークショップ / 合同シンポジウム / 構造生物学 / 研究報告書 / 遺伝学的アプローチ / 転写調節から疾患 / 公募研究 / 幹細胞と遺伝子発現制御 / 公開シンポジウム / ワークショップ / 研究成果集 / コンファランス / ニュースレター / 総括班会議 / シグナル伝達と転写因子 / DNA結合転写調節因子 / クロマチン再構成系による転写機構 / 転写伸長反応 / 基本転写因子 / シンポジウム / 報告書 / 転写開始 / 作用機構 / 転写因子間相互作用 / 転写共役因子 / KNOCKOUT MOUSE / thrombopoetin / hematopoietic stem cell / erythrocyte / megakaryoyte / ETSファミリー / MPL / トロンボポエチン / 増血幹細胞 / NF-E2 p45 / GATA gene / Colon cancer / Inflammatory Bowel Disease / 炎症 / in situハイブリダイゼーション / GATA遺伝子 / 大腸癌 / 炎症性腸疾患 / globin biosynthesis / heme bicsynthesis / erythroid transcription factor / delta-Aminolevulinate synthase / 先天性ヘム代謝障害 / δ-アミルブリン酸合成酵素 / 鉄芽球系貧血 / グロビン合成 / ヘム合成 / 赤血球系転写因子 / IL-6R / receptor tyroshine kinases / hemotopoietic stem cells / 幹細胞増幅 / IL-6 / 蛍光細胞分離装置 / gp130 / 多分化能 / 自己複製能 / 細胞運命決定因子 / AGM領域 / 血液幹細胞 / IL-6可溶性受容体 / 受容体型チロシンキナーゼ / tumor suppressor gene / oncogene / human cancer / cancer metastasis / cell-cell interaction / apoptosis / cell differentiation / cell growth / 2国間共同研究 / ヒトゲノム / DNA修復 / がん細胞 / がん抑制遺伝子 / がん遺伝子 / ヒトがん / がん転移 / 細胞間相互作用 / 細胞死 / 細胞増殖 / Genetic Diorder / Regulation of Heme Metabolism / Porphyria / δ-アミノレブリン酸脱水酵素 / ウロポルフィリノーゲンデカルボキシラーゼ / コプロポルフィリノーゲンオキシダーゼ / 先天異常 / ヘム代謝調節 / ポルフィリン症 / regulatory region / rat / gene / heme biosynthesis / delta-aminolevulinate synthase / フィードバック調節 / δーアミノレブリン酸合成酵素 / 調節領域 / ラット / ハイポキシア / 生体イメージング / Keap1-Nrf2システム / miRNA / 骨髄異形成症候群 / Fucci細胞 / バイオテクノロジー / 発生・分化 / 発現制御 / 核酸 / 細胞周期 / エピジェネティクス / 分子標的治療 / 機能性食品 / アニオン交換輸送体1 / 遺伝 / 疾患 / トラフィック / 細胞膜 / ウィルス / 細胞組織 / ウイルス / 遺伝学 / MAT1 / API2-MALT1 / API2 / MALT1 / MALTリンパ腫 / トランスレーショナリサーチ / マイクロアレー / トランスレーショナルリサーチ / アレーCGH / 悪性リンパ腫 / 白血球 / 遺伝子ターゲティング / 骨髄形成 / T細胞 / マスト細胞 / two hybrid法 / コリプレッサー / 基本転写装置 / 精子形成 / セルトリ細胞 / bZip / 二量体 / 赤白血病 / mafK / 転写 / 細胞分化決定 / EGFR / hst-1 / Midkine / amphiregulin / bFGF / aFGF / 増殖因子 / 食道癌 / インヒビター / コアクチベター / 受容体 / RNAポリメラーゼ / 転写制御因子 / 殺菌機構 / ロイシンジッパー / TBP / NMR / マクロファージ / 相互作用 / ヘテロダイマー / ホモダイマー / リン酸化 / 種特異的転写 / 遺伝子欠損マウス / Ahリセプター / STAT / 遺伝子破壊マウス / ES細胞 / c-myb / c-myc / 5-アミルブルン酸合成酵素 / c-Myc / 遺伝子解析 / 骨髓性プロトポルフィリン症 / フェロキタラ-ゼ / 5‐アミノレブリン酸合成酵素 Less
  • Research Projects

    (93 results)
  • Research Products

    (1,311 results)
  • Co-Researchers

    (251 People)
  •  Role of precancerous cells as components of the tumor microenvironmentPrincipal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Tohoku University
  •  Regulation of signal transduction via crosstalk between supersulfide and selenium

    • Principal Investigator
      斎藤 芳郎
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University
  •  Deciphering Molecular Basis for the Anti-Oxidative Stress Response and Application of the Basis for Disease Prevention and TherapyPrincipal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section H
    • Research Institution
      Tohoku University
  •  生体の酸化ストレス応答の分子メカニズム解明とその疾病予防・治療への応用Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Elucidation of cytoprotective mechanisms by structural analysis of stress sensor Keap1Principal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Tohoku University
  •  Promotion of oxygen biology on the basis of international networks

    • Principal Investigator
      Mori Yasuo
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Mechanisms of leukemogenesis by the leukemia-driving enhancerPrincipal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  The role of Nrf2 in development and carcinogenesis of NASH using gene rescue mice

    • Principal Investigator
      ISHIGE Kazunori
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      University of Tsukuba
  •  Mecahistic analysis of a protective response of skin tissue to UV genotoxicity

    • Principal Investigator
      IKEHATA Hironobu
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Tohoku University
  •  Oxygen biology: a new criterion for integrated understanding of life

    • Principal Investigator
      Mori Yasuo
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  Systemic mechanisms of response to hypoxic stressesPrincipal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Identification of leukemia-initiating cells in an inv(3)(q21q26) mouse modelPrincipal Investigator

    • Principal Investigator
      Yamamoto Masayuki
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Tohoku University
  •  The role of Nrf2 in pancreatic beta-cells; a study of new pancreatic beta-cell specific Nrf2 activation model mice

    • Principal Investigator
      Yoko Yagishita
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Search for novel physiological function of transcriptional factor Nrf2

    • Principal Investigator
      Suzuki Takafumi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  The role of Nrf2 in oxidative stress-mediated insulin resistance

    • Principal Investigator
      Akira Uruno
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  The regulatory role of Nrf2 in pathogenesis and carcinogenesis of NASH using gene rescued mice

    • Principal Investigator
      ISHIGE Kazunori
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      University of Tsukuba
  •  Roles of stress-responsive transcription factors in health and diseasePrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Analysis of leukemogenesis caused by disruption of gene regulatory mechanisms mediated by multiple transactivation domainsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Mechanism of Nrf2-mediated self-renewal of hematopoietic stem cellsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Crosstalk between chromosome modification and transcription factors in the differentiation of hematopoietic cells

    • Principal Investigator
      KITAMURA Toshio
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  転写因子Nrf1の神経細胞恒常性維持機構の解明Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  The role of Keap1-Nrf2 system in oxidative stress response of pancreatic β-cells

    • Principal Investigator
      URUNO Akira
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Research Field
      General medical chemistry
    • Research Institution
      Tohoku University
  •  Novel prevention of development of life style-related liver diseases and liver carcinogenesis through an activation of transcription factor induced by functional foods

    • Principal Investigator
      UTSUNOMIYA Hirotoshi, 中原 朗
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Eating habits, studies on eating habits
    • Research Institution
      Wakayama Medical University
      University of Tsukuba
  •  From the ER to the plasma membrane : Vesicular transport of membrane skeleton units and the diseases

    • Principal Investigator
      INABA Mutsumi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Clinical veterinary science
    • Research Institution
      Hokkaido University
  •  Molecular Mechanisms of Adaptive Responses to Food and OxygenPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Tohoku University
  •  転写因子の発現量依存的な細胞運命決定機構の解明Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
      University of Tsukuba
  •  Roles of transcription factors for carcinogenesis and carcinogenesisdefensePrincipal Investigator

    • Principal Investigator
      MASAYUKI Yamamoto
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
      University of Tsukuba
  •  Study for the molecular mechanism of oxidative stress responsive transcriptionPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  Genetic and Epigenetic Dysregulation in Cancer

    • Principal Investigator
      NODA Tetsuo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
      Tohoku University
  •  Molecular pathology for down-regulation of erythroid-specific genes in prion diseases

    • Principal Investigator
      INABA Mutsumi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Applied veterinary science
    • Research Institution
      Hokkaido University
  •  Gene manipulation of hypoxia inducible gene regulation

    • Principal Investigator
      IMAGAWA Shigehiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  Transcription factor regulation of malignant cell transformation and its repressionPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  Molecular mechanisms for hemato-vascular formationPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  赤芽球の増殖・分化・アポトーシスの制御におけるGATA因子の役割の解明Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  転写制御複合体形成のダイナミクスとその生物機能の解明Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  分化方向性の制御から挑む再生医工学Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  Sensitive detection of air-born mutagens and their evaluation using gene knockout mice

    • Principal Investigator
      AOKI Yasunobu
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Environmental pharmacy
    • Research Institution
      National Institute for Environmental Studies
  •  Molecular mechanisms for the assembly of the red cell membrane skeleton during erythroid cell development

    • Principal Investigator
      INABA Mutsumi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Analysis of lymph node metastasis of oral cancer by using peroxiredoxin I knockout mouse

    • Principal Investigator
      YOSHIDA Hiroshi
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      University of Tsukuba
  •  Construction of a repertoire of genetically altered mice for evaluating the toxicity of chemicals

    • Principal Investigator
      MAEDA Shuichiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Hygiene
    • Research Institution
      University of Yamanashi
      山梨医科大学
  •  Functional analysis of BTEB and BTEB2 transcription factors by gene-targeting technology

    • Principal Investigator
      FUJII Yoshiaki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      University of Tsukuba
      Tohoku University
  •  Functional Contribution of Small Maf Proteins in Hematopoietic Cells

    • Principal Investigator
      MOTOHASHI Hozumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  Investigation of biological function of thioredoxin by construction of thioredoxin knock down mice

    • Principal Investigator
      MASUTANI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      KYOTO UNIVERSITY
  •  Gene Modification of Oxygen Responsiveness by Erythropoietin Gene

    • Principal Investigator
      IMAGAWA Shigehiko
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      University of Tsukuba
  •  転座関連遺伝子及び転写因子による細胞分化とがん化の分子機構

    • Principal Investigator
      瀬戸 加大
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Analysis of biological function of regulatory network composed of bZip transcription factorsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  Molecular mechanism for the assembly of red cell membrane skeletons based on pathobiology of congenital hemolytic anemia in cattle

    • Principal Investigator
      INABA Mutsumi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  Development of monitoring system of toxic chemicals base on the Nrf2-dependent detoxification pathwayPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  APPLICATION OF GENE MANIPULATION TECHNOLOGY TO GENERATION OF MODEL ANIMALS FOR ENVIRONMENTAL ASSESSMENTPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for University and Society Collaboration
    • Research Field
      Pathological medical chemistry
    • Research Institution
      UNIVERSITY OF TSUKUBA
  •  血液細胞の分化と機能発現の制御機構の解明Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      University of Tsukuba
  •  Nrf2による新しい酸化ストレス応答機構の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  Study on a new defence system against oxidative stress

    • Principal Investigator
      ISHII Tetsuo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  Analysis of GATA transcription factors functions on development and differentiation of hematopoietic cells.

    • Principal Investigator
      TAKAHASHI Satoru
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  Function of bridging molecules in enhancer-promoter communication during erythropoieis

    • Principal Investigator
      KOBAYASHI Makoto
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  転写調節による造血分化制御

    • Principal Investigator
      仲野 徹
    • Project Period (FY)
      1998 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      Osaka University
  •  Applications of Tissue-specific Transcription Factor in Animal Gene Therapy

    • Principal Investigator
      INABA Mutsumi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied veterinary science
    • Research Institution
      The University of Tokyo
  •  Gene manipulation of heme synthetic pathway enzymes

    • Principal Investigator
      HAYASHI Norio
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  エリスロポエチン遺伝子の発現調節機構の解析

    • Principal Investigator
      IMAGAWA Shigehiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Jichi Medical University
  •  小Maf群転写因子を用いた形質転換細胞の分化誘導Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  GENETIC CONTROL OF HEMATOPOIETIC CELL DOFFERENTIATION

    • Principal Investigator
      IGARASHI Kazuhiko
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
      University of Tsukuba
  •  Transcriptional mechanisms controlling organized function in vertebrate

    • Principal Investigator
      FUJII-KURIYAMA Yoshiaki
    • Project Period (FY)
      1997 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tohoku University
  •  Target genes and biological role of transcription factors in animal

    • Principal Investigator
      ISHII Shunsuke
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      RIKEN INSTITUTE
  •  Regulation and Function of Erythroid Transcription Factors.Principal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  Regulation of Disease Susceptibility through Gene Introduction of Transcriptiom Factors.Principal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  Development of New Therapeutic Strategy for Autoimmune Diseases through Gene Introduction of Oncogene c-maf.

    • Principal Investigator
      TAKAHASHI Satoru
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
  •  細胞の機能分化に関わる遺伝子制御ネットワーク-転写因子間相互作用-

    • Principal Investigator
      FUJII-KURIYAMA Yoshiaki, HANDA Hiroshi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
      Tokyo Institute of Technology
  •  生殖細胞と支持細胞の機能的連関とGATA転写因子群

    • Principal Investigator
      高橋 智
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  高等動物細胞の遺伝子発現における転写因子の相互作用と生物作用の分子機構

    • Principal Investigator
      藤井 義明
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Tohoku University
  •  Transcription factors regulating the erytnroid and megakaryocytic cell differentiation.

    • Principal Investigator
      MINEGISHI Naoko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      University of Tsukuba
      Tohoku University
  •  転写因子群による赤血球特異的な遺伝子発現制御機序の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  赤血球系転写因子群とMaf関連蛋白質による赤血球分化の制御とその異常の解析

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  生殖細胞と支持細胞の機能的関連とGATA転写因子群Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      University of Tsukuba
  •  Molecular Mechanism of Erythroid Differentiation

    • Principal Investigator
      FUJITA Hiroyoshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Multiple transcription factors regulation of erythroid cell differeutiation mechanisms.Principal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      University of Tsukuba
  •  Possible involvement of vascular cells-related transcription factors in human inflammatory diseases and cancer tissue.

    • Principal Investigator
      OHTANI Haruo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  転写因子群による赤血球特異的な遺伝子発現調節機序の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  細胞分化の決定と癌遺伝子の役割

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  癌遺伝子mafの関連遺伝子産胸による赤血球系転写因子NF-E2の機能変換

    • Principal Investigator
      五十嵐 和彦
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  GATA転写因子群による細胞特異的転写調節機序の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      Tohoku University
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Showa University
      The University of Tokyo
  •  Purification and ampliefication of hematopoietic stem cells

    • Principal Investigator
      SUDA Toshio
    • Project Period (FY)
      1994 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  細胞分化の決定と癌遺伝子の役割

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  ヘム生合成異常による病態の分子機構:鉄芽球性貧血および骨髄性プロトポルフィリン症

    • Principal Investigator
      林 典夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  GATA転写因子群をコードする遺伝子の構造と発現調節機序の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  食道癌に発現する増殖因子の検討-食道癌の増殖の特性と悪性度に関連して-

    • Principal Investigator
      片山 正文
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Molecular analyzes of heme regulation and its disorders.

    • Principal Investigator
      SHIBAHARA Shigeki
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Tohoku University
  •  細胞分化の決定と癌移伝子の役割

    • Principal Investigator
      帯刀 益夫
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  ヘム生合成異常による病態の分子機構:鉄芽球性貧血および骨髄性プロトポルフィリン症

    • Principal Investigator
      林 典夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Structure and function of the regulatory region of the gene encoding non-specific form delta-aminolevulinate synthase

    • Principal Investigator
      HAYASHI Norio
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  Analysis of the erythroid-specific gene expression by GATA trenscription factorsPrincipal Investigator

    • Principal Investigator
      YAMAMOTO Masayuki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tohoku University
  •  転写因子GATA(NF‐EI)群をコ-ドする遺伝子の構造と発現調節機序の解析Principal Investigator

    • Principal Investigator
      山本 雅之
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  ヘム生合成異常による病態の分子機構:鉄芽球性貧血および骨髓性プロトポルフィリン症

    • Principal Investigator
      林 典夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Coupled Expression of The Genes Encoding The Constituents of The Glycine Cleavage System in Chicken

    • Principal Investigator
      HIRAGA Koichi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Toyama Medical and Pharmaceutical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 1999 1998 Other

All Journal Article Presentation Book Patent Other

  • [Book] 人体の細胞生物学 : カラー図解 第3章3.遺伝子発現の調節2018

    • Author(s)
      鈴木隆史、山本雅之
    • Total Pages
      271
    • Publisher
      日本医事新報社
    • ISBN
      9784784932320
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Book] 肝胆膵 HER family:肝内胆管癌のpotential drug targets2016

    • Author(s)
      川本 徹,山本雅一,正田純一
    • Total Pages
      176
    • Publisher
      メディカルビュー社
    • Data Source
      KAKENHI-PROJECT-15K15488
  • [Book] New Horizon of Herbal Medicines2016

    • Author(s)
      Shoda J, Warabi E, Okada K, Yamamoto M
    • Total Pages
      264
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Book] 肝胆膵 HER family:肝内胆管癌のpotential drug targets2016

    • Author(s)
      川本 徹,山本雅一,正田純一
    • Total Pages
      176
    • Publisher
      メディカルビュー社
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Book] New Horizon of Herbal Medicines2016

    • Author(s)
      Shoda J, Warabi E, Okada K, Yamamoto M
    • Total Pages
      264
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-15K15488
  • [Book] Molecular Nutrition and Diabetes. Section 3, 34. Nrf2-mediated gene regulations and glucose homeostasis2015

    • Author(s)
      Yoko Yagishita, Akira Uruno, Masayuki Yamamoto
    • Publisher
      Elsevier.B.V.
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Book] Molecular Nutrition and Diabetes, 1st Edition.2015

    • Author(s)
      Yagishita Y, Uruno A, Yamamoto M
    • Total Pages
      400
    • Publisher
      Elsevier Science B.V.
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Book] Molecular Nutrition and Diabetes2015

    • Author(s)
      Yagishita Y, Uruno A and Yamamoto M.
    • Total Pages
      400
    • Publisher
      Elsevier
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Book] 肝内胆管癌の新規バイオマーカー2014

    • Author(s)
      正田純一,松田厚志,久野 敦,池原 譲,成松 久,大河内信弘,山本雅一,中沼安二
    • Total Pages
      3
    • Publisher
      Hepatology Practice 文光堂
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Book] がんー疾患モデルの作製と利用2012

    • Author(s)
      鈴木未来子,山本雅之(分担執筆)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Book] Gallbladder Cancer-Pathogenesis and Molecular Targeting Strategies for Therapeutic Options.(Gallbladder Cancer, Christopher V Aiello)2012

    • Author(s)
      Shoda, J, Kawamoto T, Yamamoto, M
    • Publisher
      NOVA Science Publishers(In press)
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Book] 腎と透析2010

    • Author(s)
      峯岸直子、山本雅之
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Book] Diabetes Frontier2010

    • Author(s)
      宇留野晃、森口尚、山本雅之
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Book] Diabetes Frontier2010

    • Author(s)
      宇留野晃、森口尚、山本雅之
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Book] 転写制御とエピジェネティクス-ゲノムでコードに向けて-2008

    • Author(s)
      鈴木隆史、山本雅之
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Book] Keap1-Nrf2システムによる酸化ストレス・親電子性物質応答機構「酸化ストレスの医学」2008

    • Author(s)
      小林聡・山本雅之
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Differential squamous cell fates elicited by NRF2 gain of function versus KEAP1 loss of function2024

    • Author(s)
      Takahashi Jun、Suzuki Takafumi、Sato Miu、Nitta Shuji、Yaguchi Nahoko、Muta Tatsuki、Tsuchida Kouhei、Suda Hiromi、Morita Masanobu、Hamada Shin、Masamune Atsushi、Takahashi Satoru、Kamei Takashi、Yamamoto Masayuki
    • Journal Title

      Cell Reports

      Volume: 43 Issue: 4 Pages: 114104-114104

    • DOI

      10.1016/j.celrep.2024.114104

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
  • [Journal Article] A Point Mutation at C151 of<i>Keap1</i>of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me)2023

    • Author(s)
      Gatbonton-Schwager Tonibelle、Yagishita Yoko、Joshi Tanvi、Wakabayashi Nobunao、Srinivasan Harini、Suzuki Takafumi、Yamamoto Masayuki、Kensler Thomas W.
    • Journal Title

      Molecular Pharmacology

      Volume: 104 Issue: 2 Pages: 51-61

    • DOI

      10.1124/molpharm.123.000671

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06876, KAKENHI-PROJECT-19H05649
  • [Journal Article] A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells2023

    • Author(s)
      Baird Liam、Taguchi Keiko、Zhang Anqi、Takahashi Yushi、Suzuki Takafumi、Kensler Thomas W.、Yamamoto Masayuki
    • Journal Title

      Redox Biology

      Volume: 66 Pages: 102845-102845

    • DOI

      10.1016/j.redox.2023.102845

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 activation improves experimental rheumatoid arthritis2023

    • Author(s)
      Zhang Anqi、Suzuki Takafumi、Adachi Saki、Yoshida Eiki、Sakaguchi Shimon、Yamamoto Masayuki
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 207 Pages: 279-295

    • DOI

      10.1016/j.freeradbiomed.2023.07.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06876, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
  • [Journal Article] Selective Elimination of NRF2-Activated Cells by Competition With Neighboring Cells in the Esophageal Epithelium2023

    • Author(s)
      Hirose Wataru、Horiuchi Makoto、Li Donghan、Motoike Ikuko N.、Zhang Lin、Nishi Hafumi、Taniyama Yusuke、Kamei Takashi、Suzuki Mikiko、Kinoshita Kengo、Katsuoka Fumiki、Taguchi Keiko、Yamamoto Masayuki
    • Journal Title

      Cellular and Molecular Gastroenterology and Hepatology

      Volume: 15 Issue: 1 Pages: 153-178

    • DOI

      10.1016/j.jcmgh.2022.09.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-21K16466, KAKENHI-PROJECT-19H05649
  • [Journal Article] Effects of NRF2 polymorphisms on safety and efficacy of bardoxolone methyl: subanalysis of TSUBAKI study2023

    • Author(s)
      Ikejiri Kazuaki、Suzuki Takafumi、Muto Satsuki、Takama Hirotaka、Yamawaki Kengo、Miyazawa Tatsuya、Urakawa Itaru、Aoki Yuichi、Otsuki Akihito、Katsuoka Fumiki、Kinoshita Kengo、Nangaku Masaomi、Akizawa Tadao、Yamamoto Masayuki
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 28 Issue: 3 Pages: 225-234

    • DOI

      10.1007/s10157-023-02427-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 alleviates spaceflight-induced immunosuppression and thrombotic microangiopathy in mice2023

    • Author(s)
      Shimizu Ritsuko、Hirano Ikuo、Hasegawa Atsushi、Suzuki Mikiko、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Uruno Akira、Suzuki Norio、Yumoto Akane、Okada Risa、Shirakawa Masaki、Shiba Dai、Takahashi Satoru、Suzuki Takafumi、Yamamoto Masayuki
    • Journal Title

      Communications Biology

      Volume: 6 Issue: 1 Pages: 875-875

    • DOI

      10.1038/s42003-023-05251-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19396, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-23KK0137, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-23K10820, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
  • [Journal Article] Whole blood transcriptome analysis for age- and gender-specific gene expression profiling in Japanese individuals2023

    • Author(s)
      Aoki YI, Taguchi K, Anzawa H, Kawashima J, Ishida N, Otuki A, Hasegawa A, Baird L, Suzuki T, Motoike IN, Ohneda K, Kumada K, Katsuoka F, Kinoshita K, Yamamoto M.
    • Journal Title

      J Biochem

      Volume: Online ahead of print. Issue: 6 Pages: 611-627

    • DOI

      10.1093/jb/mvae008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-23K06409, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-21K06816, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-19H05649
  • [Journal Article] The β-TrCP-Mediated Pathway Cooperates with the Keap1-Mediated Pathway in Nrf2 Degradation <i>In Vivo</i>2022

    • Author(s)
      Kuga Ayumi、Tsuchida Kouhei、Panda Harit、Horiuchi Makoto、Otsuki Akihito、Taguchi Keiko、Katsuoka Fumiki、Suzuki Mikiko、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 42 Issue: 7 Pages: 1-22

    • DOI

      10.1128/mcb.00563-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22K15376, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice2022

    • Author(s)
      Liu Yexin、Uruno Akira、Saito Ritsumi、Matsukawa Naomi、Hishinuma Eiji、Saigusa Daisuke、Liu Hong、Yamamoto Masayuki
    • Journal Title

      Redox Biology

      Volume: 58 Pages: 102525-102525

    • DOI

      10.1016/j.redox.2022.102525

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20K07352
  • [Journal Article] The isoquinoline PRL-295 increases the thermostability of Keap1 and disrupts its interaction with Nrf22022

    • Author(s)
      Dayalan Naidu S、Suzuki T、Dikovskaya D、Knatko EV、Higgins M、Sato M、Novak M、Villegas JA、Moore TW、Yamamoto M、Dinkova-Kostova AT.
    • Journal Title

      iScience

      Volume: 25 Issue: 1 Pages: 103703-103703

    • DOI

      10.1016/j.isci.2021.103703

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-19H05649
  • [Journal Article] Target Gene Diversity of the Nrf1-MafG Transcription Factor Revealed by a Tethered Heterodimer2022

    • Author(s)
      Katsuoka Fumiki、Otsuki Akihito、Hatanaka Nozomi、Okuyama Haruna、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 42 Issue: 3

    • DOI

      10.1128/mcb.00520-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16511, KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 protects against radiation-induced oral mucositis via antioxidation and keratin layer thickening2022

    • Author(s)
      Wakamori Shun、Taguchi Keiko、Nakayama Yuki、Ohkoshi Akira、Sporn Michael B.、Ogawa Takenori、Katori Yukio、Yamamoto Masayuki
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 188 Pages: 206-220

    • DOI

      10.1016/j.freeradbiomed.2022.06.239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat2022

    • Author(s)
      Oo Swe Mar、Oo Hein Ko、Takayama Hiroaki、Ishii Kiyo-aki、Takeshita Yumie、Goto Hisanori、Nakano Yujiro、Kohno Susumu、Takahashi Chiaki、Nakamura Hiroyuki、Saito Yoshiro、Matsushita Mami、Okamatsu-Ogura Yuko、Saito Masayuki、Takamura Toshinari
    • Journal Title

      Cell Reports

      Volume: 38 Issue: 13 Pages: 110566-110566

    • DOI

      10.1016/j.celrep.2022.110566

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-21K08572, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K19503, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-22K11772, KAKENHI-PROJECT-22K19686, KAKENHI-PROJECT-19H03882, KAKENHI-PROJECT-21H02571, KAKENHI-PROJECT-18K11013, KAKENHI-PROJECT-20K07612, KAKENHI-PROJECT-21K19321, KAKENHI-PLANNED-21H05270, KAKENHI-PROJECT-20H00488
  • [Journal Article] Multifaceted Roles of the KEAP1-NRF2 System in Cancer and Inflammatory Disease Milieu2022

    • Author(s)
      Panda Harit、Wen Huaichun、Suzuki Mikiko、Yamamoto Masayuki
    • Journal Title

      Antioxidants

      Volume: 11 Issue: 3 Pages: 538-538

    • DOI

      10.3390/antiox11030538

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Halofuginone micelle nanoparticles eradicate Nrf2-activated lung adenocarcinoma without systemic toxicity2022

    • Author(s)
      Panda Harit、Suzuki Mikiko、Naito Mitsuru、Saito Ritsumi、Wen Huaichun、Baird Liam、Uruno Akira、Miyata Kanjiro、Yamamoto Masayuki
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 187 Pages: 92-104

    • DOI

      10.1016/j.freeradbiomed.2022.05.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20K07352
  • [Journal Article] AHR and NRF2 in Skin Homeostasis and Atopic Dermatitis2022

    • Author(s)
      Edamitsu T, Taguchi K, Okuyama R, Yamamoto M
    • Journal Title

      Antioxidants

      Volume: 11 Issue: 2 Pages: 227-227

    • DOI

      10.3390/antiox11020227

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
  • [Journal Article] Novel NRF2‐activated cancer treatments utilizing synthetic lethality2022

    • Author(s)
      Baird Liam、Kensler Thomas W.、Yamamoto Masayuki
    • Journal Title

      IUBMB Life

      Volume: 74 Issue: 12 Pages: 1209-1231

    • DOI

      10.1002/iub.2680

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] The KEAP1-NRF2 system and esophageal cancer2022

    • Author(s)
      Hirose W, Oshikiri H, Taguchi K, Yamamoto M
    • Journal Title

      Cancers

      Volume: 14 Issue: 19 Pages: 4702-4702

    • DOI

      10.3390/cancers14194702

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06906, KAKENHI-PROJECT-22K19450, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-19H05649
  • [Journal Article] Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction2021

    • Author(s)
      Zhang Anqi、Suzuki Takafumi、Adachi Saki、Naganuma Eriko、Suzuki Norio、Hosoya Tomonori、Itoh Ken、Sporn Michael B.、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 41 Issue: 11 Pages: 0023621-0023621

    • DOI

      10.1128/mcb.00236-21

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-23K21372
  • [Journal Article] Novel method for evaluating the health condition of mice in space through a video downlink2021

    • Author(s)
      YUMOTO Akane、KOKUBO Toshiaki、IZUMI Ryutaro、SHIMOMURA Michihiko、FUNATSU Osamu、TADA Motoki N.、OTA-MURAKAMI Naoko、IINO Kayoko、SHIRAKAWA Masaki、MIZUNO Hiroyasu、KUDO Takashi、TAKAHASHI Satoru、SUZUKI Takafumi、URUNO Akira、YAMAMOTO Masayuki、SHIBA Dai
    • Journal Title

      Exp. Anim.

      Volume: 70 Issue: 2 Pages: 236-244

    • DOI

      10.1538/expanim.20-0102

    • NAID

      130008037417

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 plays a critical role in the metabolic response during and after spaceflight2021

    • Author(s)
      Uruno A、Saigusa D、Suzuki T、Yumoto A、Nakamura T、Matsukawa N、Yamazaki T、Saito R、Taguchi K、Suzuki M、Suzuki N、Otsuki A、Katsuoka F、Hishinuma E、Okada R、Koshiba S、Tomioka Y、Shimizu R、Shirakawa M、Kensler TW.、Shiba D、Yamamoto M
    • Journal Title

      Communications Biology

      Volume: 4 Issue: 1 Pages: 1381-1381

    • DOI

      10.1038/s42003-021-02904-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03555, KAKENHI-PROJECT-20H03374, KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-23K21372
  • [Journal Article] The KEAP1-NRF2 system as a molecular target of cancer treatment2021

    • Author(s)
      Taguchi K, Yamamoto M
    • Journal Title

      Cancers

      Volume: 13 Issue: 1 Pages: 46-46

    • DOI

      10.3390/cancers13010046

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-16H06276
  • [Journal Article] CL316243 treatment mitigates the inflammation in white adipose tissues of juvenile adipocyte-specific Nfe2l1 knockout mice2021

    • Author(s)
      Wang Zhendi、Hou Yongyong、Ren Suping、Liu Zhiyuan、Zuo Zhuo、Huang Sicui、Wang Wanqi、Wang Huihui、Chen Yanyan、Xu Yuanyuan、Yamamoto Masayuki、Zhang Qiang、Fu Jingqi、Pi Jingbo
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 165 Pages: 289-298

    • DOI

      10.1016/j.freeradbiomed.2021.01.043

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] The Transcription Factor MAFF Regulates an Atherosclerosis Relevant Network Connecting Inflammation and Cholesterol Metabolism2021

    • Author(s)
      von Scheidt Moritz、Zhao Yuqi、de Aguiar Vallim Thomas Q.、Che Nam、Wierer Michael、Seldin Marcus M.、Franzen Oscar、Kurt Zeyneb、Pang Shichao、Bongiovanni Dario、Yamamoto Masayuki、Edwards Peter A.、Ruusalepp Arno、Kovacic Jason C.、Mann Matthias、Bjorkegren Johan L.M.、Lusis Aldons J.、Yang Xia、Schunkert Heribert
    • Journal Title

      Circulation

      Volume: - Issue: 18 Pages: 1809-1823

    • DOI

      10.1161/circulationaha.120.050186

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 is activated by disruption of mitochondrial thiol homeostasis but not by enhanced mitochondrial superoxide production2021

    • Author(s)
      Cvetko Filip、Caldwell Stuart T.、Higgins Maureen、Suzuki Takafumi、Yamamoto Masayuki、Prag Hiran A.、Hartley Richard C.、Dinkova-Kostova Albena T.、Murphy Michael P.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100169-100169

    • DOI

      10.1074/jbc.ra120.016551

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 Activation Sensitizes K-Ras Mutant Pancreatic Cancer Cells to Glutaminase Inhibition2021

    • Author(s)
      Hamada S, Matsumoto R, Tanaka Y, Taguchi K, Yamamoto M, Masamune A.
    • Journal Title

      Int J Mol Sci.

      Volume: 22 Issue: 4 Pages: 1870-1870

    • DOI

      10.3390/ijms22041870

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K08300, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H03631
  • [Journal Article] Possible Roles of Proinflammatory Signaling in Keratinocytes Through Aryl Hydrocarbon Receptor Ligands for the Development of Squamous Cell Carcinoma2020

    • Author(s)
      Sato Yota、Fujimura Taku、Hidaka Takanori、Lyu Chunbing、Tanita Kayo、Matsushita Shigeto、Yamamoto Masayuki、Aiba Setsuya
    • Journal Title

      Frontiers in Immunology

      Volume: 11 Pages: 534323-534323

    • DOI

      10.3389/fimmu.2020.534323

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 Antioxidative System is Involved in Cytochrome P450 Gene Expression and Activity: A Delay in Pentobarbital Metabolism in Nrf2-Deficient Mice2020

    • Author(s)
      Ashino Takashi、Yamamoto Masayuki、Numazawa Satoshi
    • Journal Title

      Drug Metabolism and Disposition

      Volume: 48 Issue: 8 Pages: 673-680

    • DOI

      10.1124/dmd.120.000010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K06633, KAKENHI-PROJECT-18K08115
  • [Journal Article] Preconditioning the immature lung with enhanced Nrf2 activity protects against oxidant-induced hypoalveolarization in mice2020

    • Author(s)
      Tamatam Chandra M.、Reddy Narsa M.、Potteti Haranatha R.、Ankireddy Aparna、Noone Patrick M.、Yamamoto Masayuki、Kensler Thomas W.、Reddy Sekhar P.
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 19034-19034

    • DOI

      10.1038/s41598-020-75834-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Keap1 deletion accelerates mutant K-ras/p53-driven cholangiocarcinoma2020

    • Author(s)
      1.Nabeshima T, Hamada S, Taguchi K, Tanaka Y, Matsumoto R, Yamamoto M, Masamune A
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 318 Issue: 3 Pages: G419-G427

    • DOI

      10.1152/ajpgi.00296.2019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
  • [Journal Article] Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging2020

    • Author(s)
      Shimizu Sunao、Mimura Junsei、Hasegawa Takanori、Shimizu Eigo、Imoto Seiya、Tsushima Michiko、Kasai Shuya、Yamazaki Hiromi、Ushida Yusuke、Suganuma Hiroyuki、Tomita Hirofumi、Yamamoto Masayuki、Nakaji Shigeyuki、Itoh Ken
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 8 Pages: e0236834-e0236834

    • DOI

      10.1371/journal.pone.0236834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration2020

    • Author(s)
      Afshinnekoo Ebrahim、Scott Ryan T.、MacKay Matthew J.、Pariset Eloise、Cekanaviciute Egle、Barker Richard、Gilroy Simon、Hassane Duane、Smith Scott M.、Zwart Sara R.、Nelman-Gonzalez Mayra、Crucian Brian E.、Ponomarev Sergey A.、Orlov Oleg I.、Shiba Dai、Muratani Masafumi、Yamamoto Masayuki、以降著者省略
    • Journal Title

      Cell

      Volume: 183 Issue: 5 Pages: 1162-1184

    • DOI

      10.1016/j.cell.2020.10.050

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-20H03234
  • [Journal Article] Inhibitors of the protein-protein interaction between phosphorylated p62 and Keap1 attenuate chemoresistance in a human hepatocellular carcinoma cell line2020

    • Author(s)
      Daisuke Yasuda, Tomoyuki Ohe, Kyoko Takahashi, Riyo Imamura, Hirotatsu Kojima, Takayoshi Okabe, Yoshinobu Ichimura, Masaaki Komatsu, Masayuki Yamamoto, Tetsuo Nagano, Tadahiko Mashino
    • Journal Title

      Free Radical Research

      Volume: Mar 30 Issue: 11-12 Pages: 1-13

    • DOI

      10.1080/10715762.2020.1732955

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16322, KAKENHI-PLANNED-19H05706, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02611, KAKENHI-PROJECT-18K19417
  • [Journal Article] NRF2-Dependent Bioactivation of Mitomycin C as a Novel Strategy To Target KEAP1-NRF2 Pathway Activation in Human Cancer2020

    • Author(s)
      Baird Liam、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 41 Issue: 2 Pages: 1-18

    • DOI

      10.1128/mcb.00473-20

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
  • [Journal Article] Cellular Nrf2 levels determine cell fate during chemical carcinogenesis in esophageal epithelium2020

    • Author(s)
      Horiuchi M, Taguchi K, Hirose W, Tsuchida K, Suzuki M, Taniyama Y, Kamei T, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 41 Issue: 2

    • DOI

      10.1128/mcb.00536-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07395, KAKENHI-PROJECT-19H05649
  • [Journal Article] Nrf2 contributes to the weight gain of mice during space travel2020

    • Author(s)
      Suzuki, T., et al., Koshiba, S. et al., Yamamoto, M.(合計37名、本研究者は18番目)
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1 Pages: 496-496

    • DOI

      10.1038/s42003-020-01227-2

    • NAID

      120007161347

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07298, KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K07352, KAKENHI-PROJECT-20K09474, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02614, KAKENHI-PROJECT-18H02621, KAKENHI-ORGANIZER-15H05935, KAKENHI-WRAPUP-20H05615
  • [Journal Article] Protracted rosiglitazone treatment exacerbates inflammation in white adipose tissues of adipocyte-specific Nfe2l1 knockout mice2020

    • Author(s)
      Ren Suping、Hou Yongyong、Zuo Zhuo、Liu Zhiyuan、Wang Huihui、Xu Yuanyuan、Yamamoto Masayuki、Zhang Qiang、Fu Jingqi、Pi Jingbo
    • Journal Title

      Food and Chemical Toxicology

      Volume: 146 Pages: 111836-111836

    • DOI

      10.1016/j.fct.2020.111836

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Journal Article] Identification of Dominant Transcripts in Oxidative Stress Response by a Full-Length Transcriptome Analysis2020

    • Author(s)
      Otsuki Akihito、Okamura Yasunobu、Aoki Yuichi、Ishida Noriko、Kumada Kazuki、Minegishi Naoko、Katsuoka Fumiki、Kinoshita Kengo、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 41 Issue: 2 Pages: 1-18

    • DOI

      10.1128/mcb.00472-20

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07335, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-17K08617, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-19K16511, KAKENHI-PROJECT-19H05649
  • [Journal Article] Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers2020

    • Author(s)
      Okazaki Keito、Anzawa Hayato、Liu Zun、Ota Nao、Kitamura Hiroshi、Onodera Yoshiaki、Alam Md. Morshedul、Matsumaru Daisuke、et al.
    • Journal Title

      Nature Communications

      Volume: 11 Issue: 1 Pages: 5911-5911

    • DOI

      10.1038/s41467-020-19593-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07361, KAKENHI-PROJECT-19K07379, KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K16350, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17K08617
  • [Journal Article] Environmental pollutants and the immune response2020

    • Author(s)
      Suzuki Takafumi、Hidaka Takanori、Kumagai Yoshito、Yamamoto Masayuki
    • Journal Title

      Nature Immunology

      Volume: 21 Issue: 12 Pages: 1486-1495

    • DOI

      10.1038/s41590-020-0802-6

    • NAID

      40022683384

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-20K17336, KAKENHI-PROJECT-18H05293, KAKENHI-PROJECT-19H05649
  • [Journal Article] The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway2020

    • Author(s)
      Baird Liam、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 40 Issue: 13 Pages: 1-23

    • DOI

      10.1128/mcb.00099-20

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
  • [Journal Article] Effects of post-renal anemia treatment with the HIF-PHD inhibitor molidustat on adenine-induced renal anemia and kidney disease in mice2020

    • Author(s)
      Li Lei、Nakano Daisuke、Zhang Anqi、Kittikulsuth Wararat、Morisawa Norihiko、Ohsaki Hiroyuki、Suzuki Norio、Yamamoto Masayuki、Nishiyama Akira
    • Journal Title

      Journal of Pharmacological Sciences

      Volume: 144 Issue: 4 Pages: 229-236

    • DOI

      10.1016/j.jphs.2020.09.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H03191
  • [Journal Article] Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF22020

    • Author(s)
      Baird Liam、Suzuki Takafumi、Takahashi Yushi、Hishinuma Eiji、Saigusa Daisuke、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 40 Issue: 22 Pages: 1-22

    • DOI

      10.1128/mcb.00377-20

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19K16512
  • [Journal Article] Microenvironmental activation of Nrf2 restricts the progression of Nrf2-activated malignant tumors2020

    • Author(s)
      Makiko Hayashi, Ayumi Kuga, Mikiko Suzuki, Harit Panda, Hiroshi Kitamura, Hozumi Motohashi, Masayuki Yamamoto
    • Journal Title

      Cancer Research

      Volume: 0 Issue: 16 Pages: 00-00

    • DOI

      10.1158/0008-5472.can-19-2888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17J04895, KAKENHI-PROJECT-19K07379, KAKENHI-PUBLICLY-20H04832, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02621
  • [Journal Article] Nrf2 Lowers the Risk of Lung Injury via Modulating the Airway Innate Immune Response Induced by Diesel Exhaust in Mice2020

    • Author(s)
      Li YJ, Shimizu T, Shinkai Y, Ihara T, Sugamata T, Kato K, Kobayashi M, Hirata Y, Inagaki H, Uzuki M, Akimoto T, Umezawa M, Takeda K, Azuma A, Yamamoto M, Kawada T.
    • Journal Title

      Biomedicines

      Volume: 8 Issue: 10 Pages: 443-443

    • DOI

      10.3390/biomedicines8100443

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K10032, KAKENHI-PROJECT-19H05649
  • [Journal Article] Bardoxolone methyl analog attenuates proteinuria-induced tubular damage by modulating mitochondrial function2019

    • Author(s)
      Nagasu Hajime、Sogawa Yuji、Kidokoro Kengo、Itano Seiji、Yamamoto Toshiya、Satoh Minoru、Sasaki Tamaki、Suzuki Takafumi、Yamamoto Masayuki、Wigley W. Christian、Proksch Joel W.、Meyer Colin J.、Kashihara Naoki
    • Journal Title

      The FASEB Journal

      Volume: 33 Issue: 11 Pages: 12253-12263

    • DOI

      10.1096/fj.201900217r

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18H02828, KAKENHI-PROJECT-18K19417
  • [Journal Article] GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice2019

    • Author(s)
      Harada Nobuhiko、Hasegawa Atsushi、Hirano Ikuo、Yamamoto Masayuki、Shimizu Ritsuko
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 4 Pages: 1183-1193

    • DOI

      10.1111/cas.13959

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-19H03555
  • [Journal Article] Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles2019

    • Author(s)
      Sehsah Radwa、Wu Wenting、Ichihara Sahoko、Hashimoto Naozumi、Hasegawa Yoshinori、Zong Cai、Itoh Ken、Yamamoto Masayuki、Elsayed Ahmed Ali、El-Bestar Soheir、Kamel Emily、Ichihara Gaku
    • Journal Title

      Particle and Fibre Toxicology

      Volume: 16 Issue: 1 Pages: 47-47

    • DOI

      10.1186/s12989-019-0328-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H04279, KAKENHI-PROJECT-18K19417
  • [Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019

    • Author(s)
      Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
    • Journal Title

      Cell Reports

      Volume: 28 Issue: 3 Pages: 746-758

    • DOI

      10.1016/j.celrep.2019.06.047

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H00990, KAKENHI-PROJECT-19H01019, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17H06170, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response2019

    • Author(s)
      Nagashima Ryuichi、Kosai Hitomi、Masuo Masahiro、Izumiyama Keiko、Noshikawaji Taketo、Morimoto Motoko、Kumaki Satoru、Miyazaki Yasunari、Motohashi Hozumi、Yamamoto Masayuki、Tanaka Nobuyuki
    • Journal Title

      The Journal of Immunology

      Volume: 202 Issue: 5 Pages: 1331-1339

    • DOI

      10.4049/jimmunol.1801180

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-16K09576, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K16287, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H02621
  • [Journal Article] Generation and Molecular Characterization of Human Ring Sideroblasts: a Key Role of Ferrous Iron in Terminal Erythroid Differentiation and Ring Sideroblast Formation.2019

    • Author(s)
      Saito K, Fujiwara T, Hatta S, Morita M, Ono K, Suzuki C, Fukuhara N, Onishi Y, Nakamura Y, Kawamata S, Shimizu R, Yamamoto M, Harigae H.
    • Journal Title

      Mol Cell Biol.

      Volume: 39 Issue: 7

    • DOI

      10.1128/mcb.00387-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-17H04668, KAKENHI-PROJECT-19H03555
  • [Journal Article] Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells2019

    • Author(s)
      Katsuoka Fumiki、Otsuki Akihito、Takahashi Mizue、Ito Shin、Yamamoto Masayuki
    • Journal Title

      Molecular and Cellular Biology

      Volume: 39 Issue: 20

    • DOI

      10.1128/mcb.00273-19

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08617, KAKENHI-PROJECT-19K16511, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
  • [Journal Article] Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice.2019

    • Author(s)
      Yagishita Y, Uruno A, Chartoumpekis DV, Kensler TW, Yamamoto M.
    • Journal Title

      J Endocrinol

      Volume: 未定 Issue: 3 Pages: 403-416

    • DOI

      10.1530/joe-18-0355

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002
  • [Journal Article] Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model2019

    • Author(s)
      Panda Harit、Keleku-Lukwete Nadine、Kuga Ayumi、Fuke Nobuo、Suganuma Hiroyuki、Suzuki Mikiko、Yamamoto Masayuki
    • Journal Title

      Experimental Hematology

      Volume: 77 Pages: 51-60.e1

    • DOI

      10.1016/j.exphem.2019.08.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-18K19417
  • [Journal Article] Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic2019

    • Author(s)
      Liu Zhiyuan、Hou Yongyong、Li Lu、Yang Yang、Jia Jingkun、Hong Zhixuan、Li Tingfeng、Xu Yuanyuan、Fu Jingqi、Sun Yongxin、Yamamoto Masayuki、Wang Huihui、Pi Jingbo
    • Journal Title

      Toxicology and Applied Pharmacology

      Volume: 367 Pages: 62-70

    • DOI

      10.1016/j.taap.2019.02.003

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18K19417
  • [Journal Article] Sulforaphane enriched transcriptome of lung mitochondrial energy metabolism and provided pulmonary injury protection via Nrf2 in mice2019

    • Author(s)
      Cho Hye-Youn、Miller-DeGraff Laura、Blankenship-Paris Terry、Wang Xuting、Bell Douglas A.、Lih Fred、Deterding Leesa、Panduri Vijayalakshmi、Morgan Daniel L.、Yamamoto Masayuki、Reddy Anita J.、Talalay Paul、Kleeberger Steven R.
    • Journal Title

      Toxicology and Applied Pharmacology

      Volume: 364 Pages: 29-44

    • DOI

      10.1016/j.taap.2018.12.004

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Journal Article] NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland2018

    • Author(s)
      Ziros PG.、Habeos IG.、Chartoumpekis DV.、Ntalampyra E、Somm E、Renaud CO.、Bongiovanni M、Trougakos IP.、Yamamoto M、Kensler TW.、Santisteban P、Carrasco N、Ris-Stalpers C、Amendola E、Liao XH、Rossich L、Thomasz L、Juvenal GJ.、Refetoff S、Sykiotis GP
    • Journal Title

      Thyroid

      Volume: 28 Issue: 6 Pages: 780-798

    • DOI

      10.1089/thy.2018.0018

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002
  • [Journal Article] NRF2 mitigates acute alcohol-induced hepatic and pancreatic injury in mice2018

    • Author(s)
      Sun Jing、Fu Jingqi、Zhong Yang、Li Lu、Chen Chengjie、Wang Xiaolei、Wang Linlin、Hou Yongyong、Wang Huihui、Zhao Rui、Zhang Xixuan、Yamamoto Masayuki、Xu Yuanyuan、Pi Jingbo
    • Journal Title

      Food and Chemical Toxicology

      Volume: 121 Pages: 495-503

    • DOI

      10.1016/j.fct.2018.09.042

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Journal Article] Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF12018

    • Author(s)
      Dayalan Naidu Sharadha、Suzuki Takafumi、Yamamoto Masayuki、Fahey Jed W.、Dinkova-Kostova Albena T.
    • Journal Title

      Molecular Nutrition & Food Research

      Volume: 62 Issue: 18 Pages: 1700908-1700908

    • DOI

      10.1002/mnfr.201700908

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PROJECT-17K15590
  • [Journal Article] A Gata3 3′ Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Gata3 Expression2018

    • Author(s)
      Moriguchi Takashi、Hoshino Tomofumi、Rao Arvind、Yu Lei、Takai Jun、Uemura Satoshi、Ise Kazue、Nakamura Yasuhiro、Lim Kim-Chew、Shimizu Ritsuko、Yamamoto Masayuki、Engel James Douglas
    • Journal Title

      Molecular and Cellular Biology

      Volume: 38 Issue: 21 Pages: 21-21

    • DOI

      10.1128/mcb.00302-18

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-18H05041, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-15H04759, KAKENHI-PROJECT-16H05147
  • [Journal Article] An Overview of the Advantages of KEAP1-NRF2 System Activation During Inflammatory Disease Treatment2018

    • Author(s)
      Keleku-Lukwete Nadine、Suzuki Mikiko、Yamamoto Masayuki
    • Journal Title

      Antioxid Redox Signal

      Volume: - Issue: 17 Pages: 1746-1755

    • DOI

      10.1089/ars.2017.7358

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H06639
  • [Journal Article] KEAP1 inhibition is neuroprotective and suppresses the development of epilepsy2018

    • Author(s)
      Shekh-Ahmad Tawfeeq、Eckel Ramona、Dayalan Naidu Sharadha、Higgins Maureen、Yamamoto Masayuki、Dinkova-Kostova Albena T、Kovac Stjepana、Abramov Andrey Y、Walker Matthew C
    • Journal Title

      Brain

      Volume: 141 Issue: 5 Pages: 1390-1403

    • DOI

      10.1093/brain/awy071

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Journal Article] Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response2018

    • Author(s)
      Anusornvongchai Thitinun、Nangaku Masaomi、Jao Tzu-Ming、Wu Chia-Hsien、Ishimoto Yu、Maekawa Hiroshi、Tanaka Tetsuhiro、Shimizu Akira、Yamamoto Masayuki、Suzuki Norio、Sassa Ryoji、Inagi Reiko
    • Journal Title

      Kidney International

      Volume: 94 Issue: 3 Pages: 536-550

    • DOI

      10.1016/j.kint.2018.03.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09688, KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111003, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-18H02727, KAKENHI-PROJECT-18H02824
  • [Journal Article] Iron attenuates erythropoietin production by decreasing hypoxia-inducible transcription factor 2α concentrations in renal interstitial fibroblasts2018

    • Author(s)
      Suzuki Norio、Matsuo-Tezuka Yukari、Sasaki Yusuke、Sato Koji、Miyauchi Kenichiro、Kato Koichiro、Saito Sakae、Shimonaka Yasushi、Hirata Michinori、Yamamoto Masayuki
    • Journal Title

      Kidney International

      Volume: 94 Issue: 5 Pages: 900-911

    • DOI

      10.1016/j.kint.2018.06.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04691
  • [Journal Article] Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy2018

    • Author(s)
      Rojo Ana I.、Pajares Marta、Garcia-Yague Angel J.、Buendia Izaskun、Van Leuven Fred、Yamamoto Masayuki、Lopez Manuela G.、Cuadrado Antonio
    • Journal Title

      Redox Biology

      Volume: 18 Pages: 173-180

    • DOI

      10.1016/j.redox.2018.07.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002
  • [Journal Article] Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.2018

    • Author(s)
      Yoshida E, Suzuki T, Morita M, Taguchi K, Tsuchida K, Motohashi H, Doita M, and Yamamoto M
    • Journal Title

      Genes to Cells

      Volume: - Issue: 5 Pages: 386-392

    • DOI

      10.1111/gtc.12579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508
  • [Journal Article] Roles of the KEAP1-NRF2 system in mammalian skin exposed to UV radiation2018

    • Author(s)
      Ikehata Hironobu、Yamamoto Masayuki
    • Journal Title

      Toxicology and Applied Pharmacology

      Volume: 360 Pages: 69-77

    • DOI

      10.1016/j.taap.2018.09.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002
  • [Journal Article] The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis2018

    • Author(s)
      Yamamoto Masayuki、Kensler Thomas W.、Motohashi Hozumi
    • Journal Title

      Physiological Reviews

      Volume: 98 Issue: 3 Pages: 1169-1203

    • DOI

      10.1152/physrev.00023.2017

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PUBLICLY-18H04794, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508
  • [Journal Article] Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis2018

    • Author(s)
      Orru Claudia、Szydlowska Marta、Taguchi Keiko、Zavattari Patrizia、Perra Andrea、Yamamoto Masayuki、Columbano Amedeo
    • Journal Title

      Journal of Hepatology

      Volume: 69 Issue: 3 Pages: 635-643

    • DOI

      10.1016/j.jhep.2018.05.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15KK0325
  • [Journal Article] Sulforaphane ameliorates steroid insensitivity through an Nrf2-dependent pathway in cigarette smoke-exposed asthmatic mice2018

    • Author(s)
      Sakurai Hirofumi、Morishima Yuko、Ishii Yukio、Yoshida Kazufumi、Nakajima Masayuki、Tsunoda Yoshiya、Hayashi Shih-Yuan、Kiwamoto Takumi、Matsuno Yosuke、Kawaguchi Mio、Yamamoto Masayuki、Hizawa Nobuyuki
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 129 Pages: 473-485

    • DOI

      10.1016/j.freeradbiomed.2018.10.400

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15454, KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-18H03173, KAKENHI-PROJECT-16K09571
  • [Journal Article] C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape2018

    • Author(s)
      Dayalan Naidu Sharadha、Muramatsu Aki、Saito Ryota、Asami Soichiro、Honda Tadashi、Hosoya Tomonori、Itoh Ken、Yamamoto Masayuki、Suzuki Takafumi、Dinkova-Kostova Albena T.
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 8037-8037

    • DOI

      10.1038/s41598-018-26269-9

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-17K15590
  • [Journal Article] Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC.2018

    • Author(s)
      H. Ikehata, T. Mori, T. Douki, J. Cadet, M. Yamamoto
    • Journal Title

      Photochemical and Photobiological Sciences

      Volume: 17 Pages: 404-413

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Journal Article] Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding2018

    • Author(s)
      Kanamoto Mayu、Tsuchiya Yoshihiro、Nakao Yuki、Suzuki Takafumi、Motohashi Hozumi、Yamamoto Masayuki、Kamata Hideaki
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 11 Pages: e0203978-e0203978

    • DOI

      10.1371/journal.pone.0203978

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04794, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16K18419, KAKENHI-PROJECT-17K15590
  • [Journal Article] Simultaneous K-ras activation and Keap1 deletion cause atrophy of pancreatic parenchyma2018

    • Author(s)
      Hamada Shin、Shimosegawa Tooru、Taguchi Keiko、Nabeshima Tatsuhide、Yamamoto Masayuki、Masamune Atsushi
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol

      Volume: 314 Issue: 1 Pages: G65-G74

    • DOI

      10.1152/ajpgi.00228.2017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor2018

    • Author(s)
      Taguchi Keiko、Masui Saho、Itoh Tohru、Miyajima Atsushi、Yamamoto Masayuki
    • Journal Title

      Toxicological Sciences

      Volume: 167 Issue: 1 Pages: 227-238

    • DOI

      10.1093/toxsci/kfy233

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19417, KAKENHI-PUBLICLY-17H05497, KAKENHI-PLANNED-26111002
  • [Journal Article] Derepression of the DNA Methylation Machinery of the <i>Gata1</i> Gene Triggers the Differentiation Cue for Erythropoiesis2017

    • Author(s)
      Yu L, Takai J, Otsuki A, Katsuoka F, Suzuki M, Katayama S, Nezu M, Engel JD, Moriguchi T, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 37 Issue: 8 Pages: 592-616

    • DOI

      10.1128/mcb.00592-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-15H06037, KAKENHI-PROJECT-16H07149, KAKENHI-INTERNATIONAL-15K21759
  • [Journal Article] Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes2017

    • Author(s)
      Nezu Masahiro、Souma Tomokazu、Yu Lei、Sekine Hiroki、Takahashi Nobuyuki、Wei Andrew Zu-Sern、Ito Sadayoshi、Fukamizu Akiyoshi、Zsengeller Zsuzsanna K.、Nakamura Tomohiro、Hozawa Atsushi、Karumanchi S. Ananth、Suzuki Norio、Yamamoto Masayuki
    • Journal Title

      Sci Signal

      Volume: 10 Issue: 479

    • DOI

      10.1126/scisignal.aam5711

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-17H01519, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-17K08618
  • [Journal Article] Halofuginone enhances the chemo-sensitivity of cancer cells by suppressing NRF2 accumulation.2017

    • Author(s)
      Tsuchida K, Tsujita T, Hayashi M, Ojima A, Keleku-Lukwete N, Katsuoka F, Otsuki A, Kikuchi H, Oshima Y, Suzuki M, Yamamoto M.
    • Journal Title

      Free Radic Biol Med

      Volume: 103 Pages: 236-247

    • DOI

      10.1016/j.freeradbiomed.2016.12.041

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-16H06639, KAKENHI-PROJECT-16H07149, KAKENHI-PROJECT-26461395
  • [Journal Article] GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis2017

    • Author(s)
      Katayama Saori、Suzuki Mikiko、Yamaoka Ayaka、Keleku-Lukwete Nadine、Katsuoka Fumiki、Otsuki Akihito、Kure Shigeo、Engel James Douglas、Yamamoto Masayuki
    • Journal Title

      Blood

      Volume: 130 Issue: 7 Pages: 908-919

    • DOI

      10.1182/blood-2016-12-756767

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-16H07149
  • [Journal Article] Hyperactivation of Nrf2 in early tubular development induces nephrogenic diabetes insipidus.2017

    • Author(s)
      Suzuki T, Seki S, Hiramoto K, Naganuma E, Kobayashi EH, Yamaoka A, Baird L, Takahashi N, Sato H, Yamamoto M.
    • Journal Title

      Nat Commun

      Volume: 8 Issue: 1 Pages: 14577-14577

    • DOI

      10.1038/ncomms14577

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-16K19027, KAKENHI-PROJECT-17K15590
  • [Journal Article] Discovery of benzo[ g ]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor2017

    • Author(s)
      Yasuda Daisuke、Yuasa Akihiro、Obata Rika、Nakajima Mao、Takahashi Kyoko、Ohe Tomoyuki、Ichimura Yoshinobu、Komatsu Masaaki、Yamamoto Masayuki、Imamura Riyo、Kojima Hirotatsu、Okabe Takayoshi、Nagano Tetsuo、Mashino Tadahiko
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 27 Issue: 22 Pages: 5006-5009

    • DOI

      10.1016/j.bmcl.2017.10.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05137
  • [Journal Article] Regulation of hypoxia-inducible gene expression after HIF activation.2017

    • Author(s)
      Suzuki N, Gradin K, Poellinger L, Yamamoto M.
    • Journal Title

      Exp. Cell Res.

      Volume: 356 Pages: 182-186

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-INTERNATIONAL-15K21759
  • [Journal Article] Stress-sensing mechanisms and the physiological roles of the Keap1-Nrf2 system during cellular stress.2017

    • Author(s)
      T. Suzuki, M. Yamamoto
    • Journal Title

      Journal of Biological Chemistry

      Volume: 292 Issue: 41 Pages: 16817-16824

    • DOI

      10.1074/jbc.r117.800169

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Journal Article] NRF2 activation impairs quiescence and bone marrow reconstitution capacity of hematopoietic stem cells2017

    • Author(s)
      Murakami S, Suzuki T, Harigae H, Romeo PH, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol

      Volume: 37 Issue: 19

    • DOI

      10.1128/mcb.00086-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116
  • [Journal Article] The KEAP1-NRF2 system in cancer.2017

    • Author(s)
      Taguchi K, Yamamoto M.
    • Journal Title

      Frontiers in Oncology

      Volume: 7 Pages: 85-85

    • DOI

      10.3389/fonc.2017.00085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15KK0325, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002
  • [Journal Article] The novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2017

    • Author(s)
      Higashi C, Kawaji A, Tsuda N, Hayashi M, Saito R, Yagishita Y, Suzuki T, Uruno A, Nakamura M, Nakao K, Furusako S, Yamamoto M.
    • Journal Title

      Eur J Pharmacol

      Volume: 802 Pages: 76-84

    • DOI

      10.1016/j.ejphar.2017.02.044

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-16K19046, KAKENHI-PROJECT-17K01837, KAKENHI-PROJECT-17K15590
  • [Journal Article] Renal Anemia Model Mouse Established by Transgenic Rescue with an Erythropoietin Gene Lacking Kidney-Specific Regulatory Elements2017

    • Author(s)
      Hirano I, Suzuki N, Yamazaki S, Sekine H, Minegishi N, Shimizu R, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 37 Issue: 4

    • DOI

      10.1128/mcb.00451-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-26860625, KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-17K19680
  • [Journal Article] Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic-1 during osteoclastogenesis2017

    • Author(s)
      Sakai E., Morita M., Ohuchi M., Kido MA., Fukuma Y., Nishishita K., Okamoto K., Itoh K., Yamamoto M, and Tsukuba T
    • Journal Title

      FASEB Journal

      Volume: 31 Issue: 9 Pages: 4011-4022

    • DOI

      10.1096/fj.201700177r

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11480, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H05298, KAKENHI-PROJECT-17H04379, KAKENHI-PROJECT-16K11510, KAKENHI-PROJECT-16K15790, KAKENHI-PROJECT-25293064
  • [Journal Article] 低酸素ストレスに対する生体応答機構2017

    • Author(s)
      平野育生, 山本雅之
    • Journal Title

      ファルマシア

      Volume: 53 Pages: 201-205

    • NAID

      130005398264

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Regulation of hypoxia-inducible gene expression after HIF activation2017

    • Author(s)
      Suzuki Norio、Gradin Katarina、Poellinger Lorenz、Yamamoto Masayuki
    • Journal Title

      Exp Cell Res

      Volume: 356 Issue: 2 Pages: 182-186

    • DOI

      10.1016/j.yexcr.2017.03.013

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19680, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04691
  • [Journal Article] Inflammation and airway hyperresponsiveness after chlorine exposure are prolonged by Nrf2 deficiency in mice.2017

    • Author(s)
      Ano S, Panariti A, Allard B, O'Sullivan M, McGovern TK, Hamamoto Y, Ishii Y, Yamamoto M, Powell WS, Martin JG.
    • Journal Title

      Free Radic Biol Med

      Volume: 102 Pages: 1-15

    • DOI

      10.1016/j.freeradbiomed.2016.11.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16K15454
  • [Journal Article] Nuclear factor (erythroid derived 2)-like 2 activator increases exercise endurance capability via redox-modulation of skeletal muscles.2017

    • Author(s)
      Oh S, Komine S, Warabi E, Akiyama K, Ishii A, Ishige K, Mizokami Y, Kuga K, Horie M, Miwa Y, Iwawaki T, Yamamoto M, Shoda J
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 12902-12902

    • DOI

      10.1038/s41598-017-12926-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19887, KAKENHI-PROJECT-17K19888, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H04281, KAKENHI-PROJECT-16H03255, KAKENHI-PROJECT-17H02174, KAKENHI-PROJECT-16K14589, KAKENHI-PROJECT-16K15188, KAKENHI-PUBLICLY-16H01630, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology2017

    • Author(s)
      Rojo Ana I.、Pajares Marta、Rada Patricia、Nunez Angel、Nevado-Holgado Alejo J.、Killik Richard、Van Leuven Fred、Ribe Elena、Lovestone Simon、Yamamoto Masayuki、Cuadrado Antonio
    • Journal Title

      Redox Biol

      Volume: 13 Pages: 444-451

    • DOI

      10.1016/j.redox.2017.07.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2 promotes mutant K-ras/p53-driven pancreatic carcinogenesis2017

    • Author(s)
      Hamada Shin、Taguchi Keiko、Masamune Atsushi、Yamamoto Masayuki、Shimosegawa Tooru
    • Journal Title

      Carcinogenesis

      Volume: 38 Issue: 6 Pages: 661-670

    • DOI

      10.1093/carcin/bgx043

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04804
  • [Journal Article] Systemic activation of NRF2 alleviates lethal autoimmune inflammation in Scurfy mice2017

    • Author(s)
      Suzuki T, Murakami S, Biswal SS, Sakaguchi S, Harigae H, Yamamoto M, Motohashi H
    • Journal Title

      Mol Cell Biol

      Volume: 37 Issue: 15

    • DOI

      10.1128/mcb.00063-17

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-16H06295, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-17F17116
  • [Journal Article] Infiltration of M1, but not M2, macrophages is impaired after unilateral ureter obstruction in Nrf2-deficient mice.2017

    • Author(s)
      Sogawa Y, Nagasu H, Iwae S, Ihoriya C, Itano S, Uchida A, Kidokoro K, Taniguchi S, Takahashi M, Satoh M, Sasaki T, Suzuki T, Yamamoto M, Horng T and Kashihara N.
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 8801-8801

    • DOI

      10.1038/s41598-017-08054-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15590, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04838, KAKENHI-PROJECT-15K09146, KAKENHI-PROJECT-16K19501
  • [Journal Article] The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.2017

    • Author(s)
      Hidaka, T., Ogawa, E., Kobayashi, E.H., Suzuki, T., Funayama, R., Nagashima, T., Fujimura, T., Aiba, S., Nakayama, K., Okuyama, R., Yamamoto, M.
    • Journal Title

      Nat. Immunol.

      Volume: 18 Issue: 1 Pages: 64-73

    • DOI

      10.1038/ni.3614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26461686, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-16K10143, KAKENHI-PROJECT-17K15590, KAKENHI-PROJECT-17H04240
  • [Journal Article] Role of Keap1-Nrf2 signaling in depression and dietary intake of glucoraphanin confers stress resilience in mice2016

    • Author(s)
      Yao W, Zhang JC, Ishima T, Dong C, Yang C, Ren Q, Ma M, Han M, Wu J, Suganuma H, Ushida Y, Yamamoto M, Hashimoto K.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 30659-30659

    • DOI

      10.1038/srep30659

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2-mediated regulation of skeletal muscle glycogen metabolism.2016

    • Author(s)
      Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal SS, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 36

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Journal Article] Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling2016

    • Author(s)
      Tomokazu Souma, Masahiro Nezu, Daisuke Nakano, Shun Yamazaki, Ikuo Hirano, Hiroki Sekine, Takashi Dan, Kotaro Takeda, Guo-Hua Fong, Akira Nishiyama, Sadayoshi Ito, Toshio Miyata, Masayuki Yamamoto, Norio Suzuki
    • Journal Title

      Journal of the american society of nephlorogy

      Volume: 27 Issue: 2 Pages: 428-438

    • DOI

      10.1681/asn.2014121184

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860625, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-25670157, KAKENHI-PROJECT-26860623
  • [Journal Article] The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study2016

    • Author(s)
      Chen Y, Xu Y, Zheng H, Fu J, Hou Y, Wang H, Zhang Q, Yamamoto M, Pi J.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 478 Issue: 1 Pages: 87-92

    • DOI

      10.1016/j.bbrc.2016.07.088

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Generation of a new model rat: Nrf2 knockout rats are sensitive to aflatoxin B1 toxicity.2016

    • Author(s)
      Taguchi K, Takaku M, Egner PA, Morita M, Kaneko T, Mashimo T, Kensler TW, Yamamoto M.
    • Journal Title

      Toxicol Sci

      Volume: in press Issue: 1 Pages: 40-52

    • DOI

      10.1093/toxsci/kfw065

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460384, KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26290033, KAKENHI-PROJECT-26291005, KAKENHI-PROJECT-15KK0325, KAKENHI-INTERNATIONAL-15K21759
  • [Journal Article] Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response2016

    • Author(s)
      Saito R, Suzuki T, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M.
    • Journal Title

      Molecular and Cellular Biology.

      Volume: 36 Issue: 2 Pages: 271-284

    • DOI

      10.1128/mcb.00868-15

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815
  • [Journal Article] Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity.2016

    • Author(s)
      Yasuda D, Nakajima M, Yuasa A, Obata R, Takahashi K, Ohe T, Ichimura Y, Komatsu M, Yamamoto M, Imamura R, Kojima H, Okabe T, Nagano T, Mashino T.
    • Journal Title

      Bioorg Med Chem Lett

      Volume: 26 Issue: 24 Pages: 5956-5959

    • DOI

      10.1016/j.bmcl.2016.10.083

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05137
  • [Journal Article] Unique cistrome defined as CsMBE is strictly required for Nrf2-sMaf heterodimer function in cytoprotection.2016

    • Author(s)
      Otsuki A, Suzuki M, Katsuoka F, Tsuchida K, Suda H, Morita M, Shimizu R, Yamamoto M.
    • Journal Title

      Free Radic Biol Med

      Volume: 91 Pages: 45-57

    • DOI

      10.1016/j.freeradbiomed.2015.12.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09464, KAKENHI-PROJECT-26461395, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-15J05418, KAKENHI-PROJECT-24591404
  • [Journal Article] p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming2016

    • Author(s)
      Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T et al.
    • Journal Title

      Nature Commun

      Volume: 7 Issue: 1 Pages: 12030-12030

    • DOI

      10.1038/ncomms12030

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01190, KAKENHI-PLANNED-24112009, KAKENHI-PLANNED-25111006, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26242088, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-15H04670, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05137, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-16K10565, KAKENHI-PROJECT-15KK0325, KAKENHI-PROJECT-26000014
  • [Journal Article] The NRF2-mediated gene regulation and glucose homeostasis.2016

    • Author(s)
      Yagishita Y, Uruno A, and Yamamoto M.
    • Journal Title

      Diabetes and Nutrition

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Gata3 Hypomorphic Mutant Mice Rescued with a Yeast Artificial Chromosome Transgene Suffer a Glomerular Mesangial Cell Defect.2016

    • Author(s)
      Moriguchi T, Yu L, Otsuki A, Ainoya K, Lim KC, Yamamoto M, Engel JD.
    • Journal Title

      Mol Cell Biol

      Volume: 36 Issue: 17 Pages: 2272-2281

    • DOI

      10.1128/mcb.00173-16

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-16H07149
  • [Journal Article] Functional links between SQSTM1 and ALS2 in the pathogenesis of ALS: Cumulative impact on the protection against mutant SOD1-mediated motor dysfunction in mice2016

    • Author(s)
      Hadano, S., Mitsui, S., Pan, L., Otomo, A., Kubo, M., Sato, K., Ono, S., Onodera, W., Abe, K., Koike, M., Uchiyama, Y., Aoki, M., Warabi, E., Yamamoto, M., Ishii, T., Yanagawa, T., Shang, HF., Yoshii, F
    • Journal Title

      Hum. Mol. Genet.

      Volume: 25 Issue: 15 Pages: 3321-3340

    • DOI

      10.1093/hmg/ddw180

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01388, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-26290018, KAKENHI-PROJECT-26460485
  • [Journal Article] The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression.2016

    • Author(s)
      Sekine H, Okazaki K, Ota N, Shima H, Katoh Y, Suzuki N, Igarashi K, Ito M, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 36 Issue: 3 Pages: 407-420

    • DOI

      10.1128/mcb.00785-15

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460677, KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25670157, KAKENHI-PROJECT-26670150
  • [Journal Article] NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth2016

    • Author(s)
      Satoh H, Moriguchi T, Saigusa D, Baird L, Yu L, Rokutan H, Igarashi K, Ebina M, Shibata T, Yamamoto M.
    • Journal Title

      Cancer Res

      Volume: 76 Issue: 10 Pages: 3088-3096

    • DOI

      10.1158/0008-5472.can-15-1584

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16H05147
  • [Journal Article] Roles of renal erythropoietin-producing (REP) cells in the maintenance of systemic oxygen homeostasis.2016

    • Author(s)
      Suzuki N, Yamamoto M
    • Journal Title

      Pflugers Arch. Eur. J. Physiol.

      Volume: 468 Issue: 1 Pages: 3-12

    • DOI

      10.1007/s00424-015-1740-2

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-INTERNATIONAL-15K21759, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-25670157
  • [Journal Article] Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injuryNrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury2016

    • Author(s)
      Ashino T, Yamamoto M, Numazawa S.
    • Journal Title

      Sci Rep

      Volume: 6 Issue: 1 Pages: 26291-26291

    • DOI

      10.1038/srep26291

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15K07973, KAKENHI-PROJECT-15K19398
  • [Journal Article] Small Maf deficiency recapitulates the liver phenotypes of Nrf1- and Nrf2-deficient mice.2016

    • Author(s)
      Katsuoka F, Yamazaki H, Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 21 Issue: 12 Pages: 1309-1319

    • DOI

      10.1111/gtc.12445

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression2016

    • Author(s)
      Nezu M, Souma T, Yu L, Suzuki T, Saigusa D, Ito S, Suzuki N, Yamamoto M.
    • Journal Title

      Kidney Int

      Volume: 91 Issue: 2 Pages: 387-401

    • DOI

      10.1016/j.kint.2016.08.023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26860623, KAKENHI-PROJECT-17K19680
  • [Journal Article] Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells.2016

    • Author(s)
      Iso T, Suzuki T, Baird L, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 36 Issue: 24 Pages: 3100-3112

    • DOI

      10.1128/mcb.00389-16

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H02815, KAKENHI-PROJECT-26460354
  • [Journal Article] Efficacy estimation of erythropoiesis-stimulating agents using erythropoietin-deficient anemic mice2016

    • Author(s)
      Suzuki N, Sasaki Y, Kato K, Yamazaki S, Kurasawa M, Yorozu K, Shimonaka Y, Yamamoto M.
    • Journal Title

      Haematologica

      Volume: 101 Issue: 9 Pages: 356-360

    • DOI

      10.3324/haematol.2015.140814

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04691
  • [Journal Article] Small Maf proteins (MafF, MafG, MafK): History, structure and function2016

    • Author(s)
      Katsuoka F, Yamamoto M.
    • Journal Title

      Gene

      Volume: 586 Issue: 2 Pages: 197-205

    • DOI

      10.1016/j.gene.2016.03.058

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription.2016

    • Author(s)
      Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, Tanaka N, Moriguchi T, Motohashi H, Nakayama K, Yamamoto M.
    • Journal Title

      Nat Commun

      Volume: 7 Issue: 1 Pages: 11624-11624

    • DOI

      10.1038/ncomms11624

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-16H05147, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-15K08257, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K15228
  • [Journal Article] Transcription factor NFE2L2/NRF2 is a regulator of macroautophagy genes.2016

    • Author(s)
      Pajares M, Jimenez-Moreno N, Garcia-Yague AJ, Escoll M, de Ceballos ML, Van Leuven F, Rabano A, Yamamoto M, Rojo AI, Cuadrado A.
    • Journal Title

      Autophagy

      Volume: 12 Issue: 10 Pages: 1902-1916

    • DOI

      10.1080/15548627.2016.1208889

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2-Mediated Regulation of Skeletal Muscle Glycogen Metabolism.2016

    • Author(s)
      Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal SS, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 36 Issue: 11 Pages: 1655-1672

    • DOI

      10.1128/mcb.01095-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-16K19046, KAKENHI-PROJECT-15K16486
  • [Journal Article] Wisteria floribunda Agglutinin-Sialylated Mucin Core Polypeptide 1 is a Sensitive Biomarker for Biliary Tract Carcinoma and Intrahepatic Cholangiocarcinoma: A Multicenter Study.2016

    • Author(s)
      Shoda J, Matsuda A, Shida T, Yamamoto M, Nagino M, Tsuyuguchi T, Yasaka T, Tazuma S, Uchiyama K, Unno M, Ohkohchi N, Nakanuma Y, Kuno A, Narimatsu H.
    • Journal Title

      J Gastroenterol

      Volume: 52 Issue: 2 Pages: 218-228

    • DOI

      10.1007/s00535-016-1230-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H03255, KAKENHI-PROJECT-26282191, KAKENHI-PROJECT-26293284, KAKENHI-PROJECT-26293297, KAKENHI-PROJECT-15K15488, KAKENHI-PROJECT-15K10197, KAKENHI-PROJECT-15K21667, KAKENHI-PROJECT-15H04935, KAKENHI-PROJECT-16H05220
  • [Journal Article] Nrf2-mediated regulation of skeletal muscle glycogen metabolism.2016

    • Author(s)
      Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, Pi J, Biswal S and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 36

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Journal Article] Hypoxia Signaling Cascade for Erythropoietin Production in Hepatocytes.2015

    • Author(s)
      Tojo Y, Sekine H, Hirano I, Pan X, Souma T, Tsujita T, Kawaguchi S, Takeda N, Takeda K, Fong GH, Dan T, Ichinose M, Miyata T, Yamamoto M, Suzuki N.
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Issue: 15 Pages: 2658-2672

    • DOI

      10.1128/mcb.00161-15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860623, KAKENHI-PROJECT-26860625, KAKENHI-PLANNED-26111002, KAKENHI-PLANNED-26111003, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-25461113, KAKENHI-PROJECT-25670157
  • [Journal Article] In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain2015

    • Author(s)
      Suzuki N, Mukai HY, and Yamamoto M.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 3 Pages: e0119442-e0119442

    • DOI

      10.1371/journal.pone.0119442

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25670157, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702
  • [Journal Article] EPO産生制御機構2015

    • Author(s)
      山本雅之, 鈴木教郎, 祢津昌広
    • Journal Title

      腎と透析

      Volume: 79 Pages: 88-93

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Overexpression and Gene Amplification of HER1, HER2 and HER3 in Biliary Tract Carcinomas and the Possibility for Therapy with a HER2-Targeting Antibody Pertuzumab.2015

    • Author(s)
      Kawamoto T, Thomas M, Yamashita-Kashima Y, Shu S, Ishikura N, Ariizumi S, Yamamoto M, Kurosaki K, Shoda J
    • Journal Title

      J Gastroenterrol

      Volume: 50 Pages: 467-479

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Journal Article] CNC-bZIP Protein Nrf1-Dependent Regulation of Glucose-Stimulated Insulin Secretion.2015

    • Author(s)
      Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, Yamamoto M, Tong Q, Teng W, Qu W, Zhang Q, Andersen ME, Pi J.
    • Journal Title

      Antioxid. Redox Signal.

      Volume: 22 Issue: 10 Pages: 819-831

    • DOI

      10.1089/ars.2014.6017

    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] LSD1/KDM1A promotes hematopoietic commitment of hemangioblasts through downregulation of Etv2.2015

    • Author(s)
      Takeuchi, M., Fuse, Y., Watanabe, M., Andrea, C.S., Takeuchi, M., Nakajima, H., Ohashi, K., Kaneko, H., Kobayashi-Osaki, M., Yamamoto, M. and Kobayashi, M.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 112 Issue: 45 Pages: 13922-13927

    • DOI

      10.1073/pnas.1517326112

    • NAID

      120007135765

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26520101, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116705, KAKENHI-PROJECT-25440007
  • [Journal Article] Whole-body in vivo monitoring of inflammatory diseases exploiting human interleukin 6-luciferase transgenic mice2015

    • Author(s)
      Hayashi M, Takai J, Yu L, Motohashi H, Moriguchi T, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 35 Issue: 20 Pages: 3590-3601

    • DOI

      10.1128/mcb.00506-15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-26670150
  • [Journal Article] . An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease.2015

    • Author(s)
      17.Anand D, Agrawal S, Siddam A, Motohashi H, Yamamoto M, and Lachke SA
    • Journal Title

      Genom Data

      Volume: 5 Pages: 223-227

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts.2015

    • Author(s)
      Moriguchi T, Yu L, Takai J, Hayashi M, Satoh H, Suzuki M, Ohneda K, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Issue: 10 Pages: 1825-1837

    • DOI

      10.1128/mcb.00011-15

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590359, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-15K08285, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-26670463
  • [Journal Article] Dnmt3a regulates osteoclast differentiation by coupling to an S-adenosyl methionine-producing metabolic pathway.2015

    • Author(s)
      Nishikawa et al.
    • Journal Title

      Nature Medicine

      Volume: 21 Issue: 3 Pages: 281-287

    • DOI

      10.1038/nm.3774

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22113007, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25293423, KAKENHI-PROJECT-25670792, KAKENHI-PROJECT-25750357, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116719, KAKENHI-PROJECT-26670673, KAKENHI-PROJECT-26713010, KAKENHI-PROJECT-25253070
  • [Journal Article] Inter-Individual Differences in the Oral Bacteriome Are Greater than Intra-Day Fluctuations in Individuals.2015

    • Author(s)
      16.Sato Y, Yamagishi J, Yamashita R, Shinozaki N, Ye B, Yamada T, Yamamoto M, Nagasaki M, and Tsuboi A.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 6 Pages: e0131607-e0131607

    • DOI

      10.1371/journal.pone.0131607

    • NAID

      120006473603

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Activation of the NRF2 pathway and its impact on the prognosis of anaplastic glioma patients.2015

    • Author(s)
      Kanamori M*, Higa T, Sonoda Y, Murakami S, Dodo M, Kitamura H, Taguchi K, Shibata T, Watanabe M, Suzuki H, Shibahara I, Saito R, Yamashita Y, Kumabe T, Yamamoto M, Motohashi H*, and Tominaga T.
    • Journal Title

      Neuro-Oncology

      Volume: 17 Issue: 4 Pages: 555-565

    • DOI

      10.1093/neuonc/nou282

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670613, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26860180
  • [Journal Article] Hypoxia-Sensitive Reporter System for High-Throughput Screening2015

    • Author(s)
      Tsujita, T.; Kawaguchi, S-i.; Dan, T.; Baird, L.; Miyata, T.; Yamamoto, M.
    • Journal Title

      Tohoku J. Exp. Med.

      Volume: 235 Issue: 2 Pages: 151-159

    • DOI

      10.1620/tjem.235.151

    • NAID

      130004822440

    • ISSN
      0040-8727, 1349-3329
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J05784, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25750357, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26860168
  • [Journal Article] Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.2015

    • Author(s)
      Souma T, Nezu M, Nakano D, Yamazaki S, Hirano I, Sekine H, Dan T, Takeda K, Fong GH, Nishiyama A, Ito S, Miyata T, Yamamoto M, Suzuki N
    • Journal Title

      J. Am. Soc. Nephrol.

      Volume: -

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] The Keap1-Nrf2 system and diabetes mellitus.2015

    • Author(s)
      Uruno A, Yagishita Y, Yamamoto M.
    • Journal Title

      Arch Biochem Biophys.

      Volume: 566 Pages: 76-84

    • DOI

      10.1016/j.abb.2014.12.012

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26893008, KAKENHI-PLANNED-26111002
  • [Journal Article] Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression2015

    • Author(s)
      Moriguchi T, Suzuki M, Yu L, Takai J, Ohneda K, and Yamamoto M. “
    • Journal Title

      Mol Cell Biol

      Volume: 35 Issue: 5 Pages: 805-815

    • DOI

      10.1128/mcb.01011-14

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24591404, KAKENHI-PUBLICLY-25118722, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26461395, KAKENHI-PROJECT-26670463
  • [Journal Article] Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene2015

    • Author(s)
      Canet MJ, Merrell MD, Harder BG, Maher JM, Wu T, Lickteig AJ, Jackson JP, Zhang DD, Yamamoto M, and Cherrington NJ.
    • Journal Title

      Drug Metab Dispos.

      Volume: 43 Issue: 1 Pages: 93-99

    • DOI

      10.1124/dmd.114.060103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-26111002
  • [Journal Article] Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis.2015

    • Author(s)
      Goto M, Kitamura H, Alam MM, Ota N, Haseba T, Akimoto T, Shimizu A, Takano-Yamamoto T, Yamamoto M, Motohashi H.
    • Journal Title

      Genes Cells

      Volume: - Issue: 6 Pages: 464-480

    • DOI

      10.1111/gtc.12237

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26860180
  • [Journal Article] The Human GATA1 Gene Retains a 5' Insulator that Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts.2015

    • Author(s)
      Moriguchi T, Yu L, Takai J, Hayashi M, Satoh H, Suzuki M, Ohneda K, Yamamoto M.
    • Journal Title

      Mol. Cell. Biol.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Journal Article] Molecular basis of the Keap1-Nrf2 system2015

    • Author(s)
      T. Suzuki, M. Yamamoto
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 88 Pages: 93-100

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Journal Article] MAFG Is a Transcriptional Repressor of Bile Acid Synthesis and Metabolism.2015

    • Author(s)
      de Aguiar Vallim TQ, Tarling EJ, Ahn H, Hagey LR, Romanoski CE, Lee RG, Graham MJ, Motohashi H, Yamamoto M, Edwards PA.
    • Journal Title

      Cell Metab

      Volume: 21 Issue: 2 Pages: 298-310

    • DOI

      10.1016/j.cmet.2015.01.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-26670150, KAKENHI-PLANNED-26111002
  • [Journal Article] Molecular basis of the Keap1-Nrf2.2015

    • Author(s)
      Suzuki T, Yamamoto M
    • Journal Title

      Free Radic Biol Med.

      Volume: 88 Pages: 93-100

    • DOI

      10.1016/j.freeradbiomed.2015.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-26111002
  • [Journal Article] Amelioration of inflammation and tissue damage in sickle cell model mice by Nrf2 activation.2015

    • Author(s)
      Nadine Keleku-Lukwete, Mikiko Suzuki, Akihito Otsuki, Kouhei Tsuchida, Saori Katayama, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, Osamu Tanabe, James Douglas Engel, Masue Imaizumi, Masayuki Yamamoto
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 112 Issue: 39 Pages: 12169-12174

    • DOI

      10.1073/pnas.1509158112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460355, KAKENHI-PROJECT-26461395, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-15H02507, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-26670463
  • [Journal Article] Renal erythropoietin-producing cells in health and disease.2015

    • Author(s)
      Souma T, Suzuki N, Yamamoto M
    • Journal Title

      Front Physiol.

      Volume: 3 Pages: 167-167

    • DOI

      10.3389/fphys.2015.00167

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26860623, KAKENHI-PLANNED-26111002, KAKENHI-PUBLICLY-26116702, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-25670157
  • [Journal Article] In vivo spectrum of UVC-induced mutation in mouse skin epidermis may reflect the cytosine deamination propensity of cyclobutane pyrimidine dimers.2015

    • Author(s)
      H. Ikehata, T. Mori and M. Yamamoto
    • Journal Title

      Photochem. Photobiol.

      Volume: 91 Issue: 6 Pages: 1488-1496

    • DOI

      10.1111/php.12525

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26550042, KAKENHI-PROJECT-15H02815
  • [Journal Article] The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap12015

    • Author(s)
      Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
    • Journal Title

      Science Signaling.

      Volume: 8 Issue: 404 Pages: 404-404

    • DOI

      10.1126/scisignal.aad0667

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460354, KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-24115007, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-26650011, KAKENHI-PROJECT-26670150
  • [Journal Article] Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.2014

    • Author(s)
      Ida T, Sawa T, Ihara H, Tsucr iya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S. Matsunaga T, Yamamoto M, Ono K, Devarie-Baez N O, Xian M, Fukuto J M, Akaike T.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: (印刷中) Issue: 21 Pages: 7606-7611

    • DOI

      10.1073/pnas.1321232111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24590527, KAKENHI-PROJECT-24790263, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25430069, KAKENHI-PROJECT-25870549, KAKENHI-ORGANIZER-26111001, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26670131, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26670207
  • [Journal Article] GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells2014

    • Author(s)
      Kamata M, Okitsu Y, Fujiwara T, Kanehira M, Nakajima S, Takahashi T, Inoue A, Fukuhara N, Onishi Y, Ishizawa K, Shimizu R, Yamamoto M, and Harigae H.
    • Journal Title

      Haematologica

      Volume: 11 Pages: 1686-1696

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2 enhances myocardial clearance of toxic ubiquitinated proteins.2014

    • Author(s)
      Wang W, Li S, Wang H, Li B, Shao L, Lai Y, Horvath G, Wang Q, Yamamoto M, Janicki JS, Wang XL, Tang D, and Cui T.
    • Journal Title

      J Mol Cell Cardiol 72,

      Volume: 72 Pages: 305-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis2014

    • Author(s)
      Hiramoto K, Satoh H, Suzuki T, Moriguchi T, Pi J, Shimosegawa T, and Yamamoto M.
    • Journal Title

      Cancer Prev Res (Phila)

      Volume: 7 Pages: 835-844

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Isocitrate dehydrogenase mutation is frequently observed in giant cell tumor of bone2014

    • Author(s)
      Kato-Kaneko M, Liu X, Oki H, Ogasawara S, Nakamura T, Saidoh N, Tsujimoto Y, Matsuyama Y, Uruno A, Sugawara M, Tsuchiya T, Yamakawa M, Yamamoto M, Takagi M, Kato Y.
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 6 Pages: 744-748

    • DOI

      10.1111/cas.12413

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25460451, KAKENHI-PROJECT-26460383
  • [Journal Article] Transcription factor Nrf1 negatively regulates the cystine/glutamate transporter and lipid-metabolizing enzymes2014

    • Author(s)
      Tsujita T, Peirce V, Baird L, Matsuyama Y, Takaku M, Walsh SV, Griffin JL, Uruno A, Yamamoto M, and Hayes JD.
    • Journal Title

      Mol Cell Biol

      Volume: 34 Issue: 20 Pages: 3800-3816

    • DOI

      10.1128/mcb.00110-14

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25750357, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460383
  • [Journal Article] Keap1 inhibition attenuates glomerulosclerosis.2014

    • Author(s)
      Miyazaki Y, Shimizu A, Pastan I, Taguchi K, Naganuma E, Suzuki T, Hosoya T, Yokoo T, Saito A, Miyata T, Yamamoto M, Matsusaka T.
    • Journal Title

      Nephrol Dial Transplant

      Volume: 29 Issue: 4 Pages: 783-791

    • DOI

      10.1093/ndt/gfu002

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23591202, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112502, KAKENHI-PUBLICLY-25117703, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26461241
  • [Journal Article] Expression of N-acetylglucosaminyltransferase V in the subserosal layer correlates with postsurgical survival of pathological tumor stage 2 carcinoma of the gallbladder.2014

    • Author(s)
      Onuki K, Sugiyama H, Ishige K, Kawamoto T, Ota T, Ariizumi S, Yamato M, Kadota S, Takeuchi K, Ishikawa A, Onodera M, Onizawa K, Yamamoto M, Miyoshi E, Shoda J.
    • Journal Title

      J Gastroenterol

      Volume: 49 Pages: 702-714

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Journal Article] Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice.2014

    • Author(s)
      Hirotsu Y, Higashi C, Fukutomi T, Katsuoka F, Tsujita T, Yagishita Y, Matsuyama Y, Motohashi H, Uruno A, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 19 Issue: 8 Pages: 650-665

    • DOI

      10.1111/gtc.12165

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25750357, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-26893008
  • [Journal Article] Possible involvementof nuclear factor erythroid 2-related factor 2in the gene expression of Cyp2b10and Cyp2a52014

    • Author(s)
      Ashino T, Ohkubo-Morita H, Yamamoto M, Yoshida T, Numazawa S
    • Journal Title

      Redox Biology

      Volume: 10 Pages: 284-288

    • DOI

      10.1016/j.redox.2013.12.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790785
  • [Journal Article] An efficient quantitation method of next-generation sequencing libraries by using MiSeq sequencer.2014

    • Author(s)
      Katsuoka F, Yokozawa J, Tsuda K, Ito S, Pan X, Nagasaki M, Yasuda J, and Yamamoto M.
    • Journal Title

      Anal Biochem

      Volume: 466 Pages: 27-29

    • DOI

      10.1016/j.ab.2014.08.015

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-26111002
  • [Journal Article] Nrf2 induces fibroblast growth factor 21 in diabetic mice2014

    • Author(s)
      Furusawa Y, Uruno A, Yagishita Y, Higashi C, and Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 19 Issue: 12 Pages: 864-878

    • DOI

      10.1111/gtc.12186

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26460383, KAKENHI-PROJECT-26893008
  • [Journal Article] A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21 ; q26) by Activating EVI1 Expression2014

    • Author(s)
      Yamazaki H, Suzuki M, Otsuki A, Shimizu R, Bresnick EH, Engel JD, Yamamoto M.
    • Journal Title

      Cancer Cell

      Volume: 25 Issue: 4 Pages: 415-427

    • DOI

      10.1016/j.ccr.2014.02.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08044, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24790957, KAKENHI-PROJECT-26670463, KAKENHI-PROJECT-26860178
  • [Journal Article] Notch-Nrf2 axis: Regulation of Nrf2 gene expression and cytoprotection by Notch signaling2014

    • Author(s)
      Wakabayashi N, Skoko JJ, Chartoumpekis DV, Kimura S, Slocum SL, Noda K, Palliyaguru DL, Fujimuro M, Boley PA, Tanaka Y, Shigemura N, Biswal S, Yamamoto M, Kensler TW
    • Journal Title

      Mol Cell Biol

      Volume: 34 Issue: 4 Pages: 653-663

    • DOI

      10.1128/mcb.01408-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590103
  • [Journal Article] Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells.2014

    • Author(s)
      Murakami S, Shimizu R, Romeo PH, Yamamoto M, Motohashi H.
    • Journal Title

      Gene Cells

      Volume: 19 Pages: 239-253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Journal Article] Hematopoietic stem and progenitor cell activation during chronic dermatitis provoked by constitutively active aryl-hydrocarbon receptor driven by keratin 14 promoter2014

    • Author(s)
      Murakami S., Yamamoto M. and Motohashi H
    • Journal Title

      Toxicological Sciences

      Volume: 138 Issue: 1 Pages: 47-58

    • DOI

      10.1093/toxsci/kft273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075
  • [Journal Article] Validation of multiple single nucleotide variation calls by additional exome analysis with a semiconductor sequencer to supplement data of whole-genome sequencing of a human population2014

    • Author(s)
      Motoike IN, Matsumoto M, Danjoh I, Katsuoka F, Kojima K, Nariai N, Sato Y, Yamaguchi-Kabata Y, Ito S, Kudo H, Nishijima I, Nishikawa S, Pan X, Saito R, Saito S, Saito T, Shirota M, Tsuda K, Yokozawa J, Igarashi K, Minegishi N, Tanabe O, Fuse N, Nagasaki M, Kinoshita K, Yasuda J, and Yamamoto M.
    • Journal Title

      BMC Genomics

      Volume: 10 Issue: 1 Pages: 637-637

    • DOI

      10.1186/1471-2164-15-673

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25440254, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26461482
  • [Journal Article] Myeloid lineage-specific deletion of antioxidant system enhances tumor metastasis.2014

    • Author(s)
      Hiramoto K, Satoh H, Suzuki T, Moriguchi T, Pi J, Shimosegawa T, Yamamoto M.
    • Journal Title

      Cancer Prevention Research

      Volume: 7 Issue: 8 Pages: 835-844

    • DOI

      10.1158/1940-6207.capr-14-0094

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-25112502, KAKENHI-PLANNED-26111010, KAKENHI-PROJECT-26460354
  • [Journal Article] A regulatory network governing Gata1 and Gata2 gene transcription orchestrates erythroid lineage differentiation.2014

    • Author(s)
      Moriguchi T, Yamamoto M.
    • Journal Title

      Int J Hematol.

      Volume: 100 Issue: 5 Pages: 417-424

    • DOI

      10.1007/s12185-014-1568-0

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142
  • [Journal Article] Keap1-Nrf2系と腎臓病2014

    • Author(s)
      祢津昌広・相馬友和・山本雅之
    • Journal Title

      Annual Review腎臓

      Volume: 2014 Pages: 89-96

    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2 protects pancreatic β-cells from oxidative and nitrosative stress in diabetic model mice2014

    • Author(s)
      Yagishita Y, Fukutomi T, Sugawara A, Kawamura H, Takahashi T, Pi J, Uruno A, and Yamamoto M.
    • Journal Title

      Diabetes

      Volume: 63 Issue: 2 Pages: 605-618

    • DOI

      10.2337/db13-0909

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790306, KAKENHI-PROJECT-23390458
  • [Journal Article] Remarkable induction of UV-signature mutations at the 3'-cytosine of dipyrimidine sites except at 5'-TCG-3' in the UVB-exposed skin epidermis of xeroderma pigmentosum variant model mice.2014

    • Author(s)
      Ikehata H, Chang Y, Yokoi M, Yamamoto M, Hanaoka F
    • Journal Title

      DNA Repair

      Volume: 22 Pages: 112-122

    • DOI

      10.1016/j.dnarep.2014.07.012

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-22131008, KAKENHI-PROJECT-24310036, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26340028
  • [Journal Article] GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells.2014

    • Author(s)
      Kamata M, Okitsu Y, Fujiwara T, Kanehira M, Nakajima S, Takahashi T, Inoue A, Fukuhara N, Onishi Y, Ishizawa K, Shimizu R, Yamamoto M, Harigae H.
    • Journal Title

      Haematologica

      Volume: 99 Issue: 11 Pages: 1686-1696

    • DOI

      10.3324/haematol.2014.105692

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25860776, KAKENHI-PLANNED-26111002, KAKENHI-PROJECT-26860716
  • [Journal Article] Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury?2014

    • Author(s)
      Pomeshchik Y, Kidin I, Savchenko E, Rolova T, Yamamoto M, Levonen AL, Yla-Herttuala S, Kanninen K, Malm T, Koistinaho J
    • Journal Title

      Antioxid Redox Signal

      Volume: 20 Issue: 8 Pages: 1313-1323

    • DOI

      10.1089/ars.2013.5453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice.2014

    • Author(s)
      Shirasaki K, Taguchi K, Unno M, Motohashi H, and Yamamoto M
    • Journal Title

      Hepatology

      Volume: 59 Issue: 6 Pages: 2371-2382

    • DOI

      10.1002/hep.27020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-26670150
  • [Journal Article] Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.2014

    • Author(s)
      Ohneda K, Moriguchi T, Ohmori S, Ishijima Y, Satoh H, Philipsen S, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 34 Issue: 10 Pages: 1812-1826

    • DOI

      10.1128/mcb.01524-13

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-25860221
  • [Journal Article] NRF2 immunolocalization in human breat cancer patients as a prognostic factor.2014

    • Author(s)
      Onodera Y, Motohashi H, Takagi K, Miki Y, Shibahara Y, Watanabe M, Ishida T, Hirakawa H, Sasano H, Yamamoto M, and Suzuki T.
    • Journal Title

      Endocri Relat Cancer

      Volume: 21 Issue: 2 Pages: 241-252

    • DOI

      10.1530/erc-13-0234

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075
  • [Journal Article] The circadian clock regulates the NRF2/ARE-mediated antioxidant defence pathway in the mouse lung.2014

    • Author(s)
      Pekovic-Vaughan V, Gibbs J, Yoshitane H, Yang N, Pathiranage D, Guo B, Sagami A, Taguchi K, Bechtold D, Loudon A, Yamamoto M, Chan J, van der Horst GTJ, Fukada Y, and Meng Q-J.
    • Journal Title

      Genes Dev

      Volume: 28 Issue: 6 Pages: 548-560

    • DOI

      10.1101/gad.237081.113

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25112504, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25440041, KAKENHI-PROJECT-26460384, KAKENHI-PROJECT-24227001
  • [Journal Article] Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway2014

    • Author(s)
      Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, and Komatsu M.
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 36 Pages: 24944-24955

    • DOI

      10.1074/jbc.m114.580357

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-26253019, KAKENHI-PROJECT-26830080, KAKENHI-PROJECT-26860224
  • [Journal Article] Degradation of Keap1 activates BH3-only proteins Bim and PUMA during hepatocyte lipoapoptosis2014

    • Author(s)
      Cazanave SC, Wang X, Zhou H, Rahmani M, Grant S, Durrant DE, Klaassen CD, Yamamoto M, and Sanyal AJ.
    • Journal Title

      Cell Death Differ

      Volume: 21 Pages: 1303-1312

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Kinetic, Thermodynamic and Structural Characterizations of Association between Nrf2-DLGex Degron and Keap1.2014

    • Author(s)
      Fukutomi, T., Takagi, K., Mizushima, T., Ohuchi, N., and Yamamoto, M.
    • Journal Title

      Moll Cell Biol.

      Volume: 34 Issue: 5 Pages: 832-846

    • DOI

      10.1128/mcb.01191-13

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-25870631
  • [Journal Article] Nrf2 enhances cholangiocyte expansion in Pten-deficient livers.2014

    • Author(s)
      Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, Motohashi H, and Yamamoto M.
    • Journal Title

      Mol. Cell. Biol.

      Volume: 34 Issue: 5 Pages: 900-913

    • DOI

      10.1128/mcb.01384-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22118006, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-24116508, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670187, KAKENHI-PROJECT-26460384
  • [Journal Article] Indoxyl sulfate down-regulates SLCO4C1 transporter through up-regulation of GATA32014

    • Author(s)
      Yu L, Moriguchi T, Souma T, Takai J, Satoh H, Morito N, Engel JD, Yamamoto M
    • Journal Title

      Molecular and Cellular Biology

      Volume: 8 Issue: 11 Pages: 1929-1941

    • DOI

      10.1128/mcb.01659-13

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-26860623
  • [Journal Article] Nuclear factor erythroid 2-related factor 2 regulates toll-like receptor 4 innate responses in mouse liver ischemia-reperfusion injury through Akt-forkhead box protein O1 signaling network.2014

    • Author(s)
      Huang J, Yue S, Ke B, Zhu J, Shen XD, Zhai Y, Yamamoto M, Busuttil RW, and Kupiec-Weglinski JW.
    • Journal Title

      Transplantation

      Volume: 98 Issue: 7 Pages: 721-728

    • DOI

      10.1097/tp.0000000000000316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-26111002
  • [Journal Article] Keap 1-Nrf2 system regulates cell fate determination of hematopoietic stem cells2014

    • Author(s)
      Murakami S., Shimizu R., Romeo P. H., Yamamoto M. Motohashi H.
    • Journal Title

      Genes to Cells

      Volume: 19 Issue: 3 Pages: 239-253

    • DOI

      10.1111/gtc.12126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06582, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] PGC-1 Coactivator Activity is Required for Murine Erythropoiesis2014

    • Author(s)
      Cui S, Tanabe O, Lim K-C, Xu HE, Zhou XE, Lin JD, Shi L, Shimizu R, Schmidt L, Campbell A, Yamamoto M, and Engel JD,
    • Journal Title

      Mol Cell Biol

      Volume: 34 Issue: 11 Pages: 1956-1965

    • DOI

      10.1128/mcb.00247-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] Plasticity of renal erythropoietin-producing cells governs fibrosis2013

    • Author(s)
      Souma T, Yamazaki S, Moriguchi T, Suzuki N, Hirano I, Pan X, Minegishi N, Abe M, Kiyomoto H, Ito S, Yamamoto M
    • Journal Title

      J Am Soc Nephrol

      Volume: 24 Issue: 10 Pages: 1599-1616

    • DOI

      10.1681/asn.2013010030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24116502, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24591187, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25462533, KAKENHI-PROJECT-25670157
  • [Journal Article] The absence of macrophage Nrf2 promotes early atherogenesis2013

    • Author(s)
      Ruotsalainen AK, Inkala M, Partanen ME, Lappalainen JP, Kansanen E, Makinen PI, Heinonen SE, Laitinen HM, Heikkila, Vatanen T, Horkko S, Yamamoto M, Yla-Herttuala S, Jauhiainen M, Levonen AL
    • Journal Title

      Cardiovasc Res

      Volume: 98 Issue: 1 Pages: 107-115

    • DOI

      10.1093/cvr/cvt008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.2013

    • Author(s)
      Ichimura, Y., Waguri, S., Sou, Y., Kageyama, S., Hasegawa, J., Ishimura, R., Saito, T., Yang, Y., Kouno, T., Fukutomi, T., Hoshii, T., Atsushi, H., Takagi, K., Mizushima, T., Motohashi, H., Lee, M-S., Yoshimori, T., Tanaka, K., Yamamoto, M., and Komatsu, K.
    • Journal Title

      Mol Cell

      Volume: 51 Issue: 5 Pages: 618-631

    • DOI

      10.1016/j.molcel.2013.08.003

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21000012, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-23247034, KAKENHI-PLANNED-24112009, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790332, KAKENHI-PROJECT-24790967, KAKENHI-PLANNED-25111002, KAKENHI-PUBLICLY-25118710, KAKENHI-PROJECT-25460400, KAKENHI-PROJECT-25870631
  • [Journal Article] Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration2013

    • Author(s)
      Holmstrom KM, Baird L, Zhang Y, Hargreaves I, Chalasani A, Land JM, Stanyer L, Yamamoto M, Dinkova-Kostova AT, Abramov AY
    • Journal Title

      Biol Open

      Volume: 2 Issue: 8 Pages: 761-770

    • DOI

      10.1242/bio.20134853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death2013

    • Author(s)
      Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T.
    • Journal Title

      J Neurochem

      Volume: 127 Issue: 5 Pages: 669-680

    • DOI

      10.1111/jnc.12325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592613, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703
  • [Journal Article] 4-Hydroxy hexenal derived from docosahexaenoic acid protects endothelial cells via Nrf2 activation2013

    • Author(s)
      Ishikado A, Morino K, Nishio Y, Nakagawa F, Mukose A, Sono Y, Yoshioka N, Kondo K, Sekine O, Yoshizaki T, Ugi S, Uzu T, Kawai H, Makino T, Okamura T, Yamamoto M, Kashiwagi A, Maegawa H
    • Journal Title

      PLoS One

      Volume: 8 Issue: 7 Pages: e69415-e69415

    • DOI

      10.1371/journal.pone.0069415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591350
  • [Journal Article] Verification of the in vivo activity of three distinct cis-acting elements within the Gatal gene promoter-proximal enhancer in mice2013

    • Author(s)
      Shimizu R, Hasegawa A, Ottolenghi S, Ronchi A, Yamamoto M.
    • Journal Title

      Genes to Cells

      Volume: 18(11) Issue: 11 Pages: 1032-1041

    • DOI

      10.1111/gtc.12096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J07201, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice2013

    • Author(s)
      Eba S, Hoshikawa Y, Moriguchi T, Mitsuishi Y, Satoh H, Ishida K, Watanabe T, Shimizu T, Shimokawa H, Okada Y, Yamamoto M, Kondo T
    • Journal Title

      Am J Respir Cell Mol Biol

      Volume: 49 Pages: 324-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Establishment of erythroleukemic GAK14 cells and characterization of GATA1 N-terminal domain2013

    • Author(s)
      Mukai HY, Suzuki M, Nagano M, Ohmori S, Otsuki A, Tsuchida K, Moriguchi T, Ohneda K, Shimizu R, Ohneda O, Yamamoto M,
    • Journal Title

      Genes Cells

      Volume: 18 Issue: 10 Pages: 886-898

    • DOI

      10.1111/gtc.12084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24790735, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118722, KAKENHI-PROJECT-25860221
  • [Journal Article] Keap1-Nrf2 complex in ischemia-induced hepatocellular damage of mouse liver transplants2013

    • Author(s)
      Ke B, Shen XD, Zhang Y, Ji H, Gao F, Yue S, Kamo N, Zhai Y, Yamamoto M, Busuttil RW, Kupiec-Weglinski JW
    • Journal Title

      J Hepatol

      Volume: 59 Issue: 6 Pages: 1200-1207

    • DOI

      10.1016/j.jhep.2013.07.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis.2013

    • Author(s)
      Watanabe S, De Zan T, Ishizalki T, Yasuda S, Kamijo H, Yamada D, Aoki T, Kiyonari H, Kaneko H, Shimizu R, Yamamoto M, Goshima G, and, Narummiya S
    • Journal Title

      Cell Reports

      Volume: 5(4) Issue: 4 Pages: 926-932

    • DOI

      10.1016/j.celrep.2013.10.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J04389, KAKENHI-PROJECT-23229003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PUBLICLY-25121714
  • [Journal Article] Erythropoietin production in neuroepithelial and neural crest cells during primitive erythropoiesis2013

    • Author(s)
      Suzuki N, Hirano I, Pan X, Minegishi N, Yamamoto M
    • Journal Title

      Nature Commun

      Volume: 4 Issue: 1 Pages: 2902-2902

    • DOI

      10.1038/ncomms3902

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24116502, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25670157
  • [Journal Article] 酸化ストレス応答の新展開2013

    • Author(s)
      福富俊明、山本雅之
    • Journal Title

      医学のあゆみ

      Volume: 247 Pages: 731-736

    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] The Keap1-Nrf2 system prevents onset of diabetes mellitus2013

    • Author(s)
      Uruno A, Furusawa Y, Yagishita Y, Fukutomi T, Muramatsu H, Negishi T, Sugawara A, Kensler TW, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 33 Issue: 15 Pages: 2996-3010

    • DOI

      10.1128/mcb.00225-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790306
  • [Journal Article] Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis2013

    • Author(s)
      Satoh H, Moriguchi T, Takai J, Ebina M, Yamamoto M
    • Journal Title

      Cancer Res

      Volume: 73 Issue: 13 Pages: 4158-4168

    • DOI

      10.1158/0008-5472.can-12-4499

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] A mouse model of adult-onset anaemia due to erythropoietin deficiency2013

    • Author(s)
      Yamazaki S, Souma T, Hirano I, Pan X, Minegishi N, Suzuki N, Yamamoto M
    • Journal Title

      Nature Communications

      Volume: 4 Issue: 1 Pages: 1950-1950

    • DOI

      10.1038/ncomms2950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07924, KAKENHI-PUBLICLY-24116502, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-25670157
  • [Journal Article] Regulatory nexus of synthesis and degradation deciphers cellular Nrf2 expression levels.2013

    • Author(s)
      Suzuki T, Shibata T, Takaya K, Shiraishi K, Kohno T, Kunitoh H, Tsuta K, Furuta K, Goto K, Hosoda F, Sakamoto H, Motohashi H and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 33 Issue: 12 Pages: 2402-2412

    • DOI

      10.1128/mcb.00065-13

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790340, KAKENHI-PUBLICLY-25112502
  • [Journal Article] The role of the Nrf2-mediated defense system in corneal epithelial wound healing2013

    • Author(s)
      Hayashi R, Himori N, Taguchi K, Ishikawa Y, Uesugi K, Ito M, Duncan T, Tsujikawa M, Nakazawa T, Yamamoto M, Nishida K
    • Journal Title

      Free Radic Biol Med

      Volume: 61C Pages: 333-342

    • DOI

      10.1016/j.freeradbiomed.2013.04.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703, KAKENHI-PROJECT-25670731
  • [Journal Article] Erythropoietin contributes to slow oxidative muscle fiber specification via PGC-1a and AMPK activation2013

    • Author(s)
      Wang L, Jia Y, Rogers H, Suzuki N, Gassmann M, Wang Q, McPherron AC, Kopp J, Yamamoto M, Noguchi CT
    • Journal Title

      Int J Biochem Cell Biol

      Volume: 45 Issue: 7 Pages: 1155-1164

    • DOI

      10.1016/j.biocel.2013.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PUBLICLY-24116502
  • [Journal Article] Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome2013

    • Author(s)
      Xue P, Hou Y, Chen Y, Yang B, Fu J, Zheng H, Yarborough K, Woods CG, Liu D, Yamamoto M, Zhang Q, Andersen ME, Pi J
    • Journal Title

      Diabetes

      Volume: 62 Issue: 3 Pages: 845-854

    • DOI

      10.2337/db12-0584

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Transforming growth factor-&βinduces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.2013

    • Author(s)
      Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Ogami T, Koinuma D, Kato M.
    • Journal Title

      J Biol Chem

      Volume: 288 Issue: 28 Pages: 20658-20667

    • DOI

      10.1074/jbc.m113.450478

    • NAID

      120007136878

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-25293092, KAKENHI-PROJECT-25460472, KAKENHI-PROJECT-25640059
  • [Journal Article] Redox-sensitive transcription factor Nrf2 regulates vascular smooth muscle cell migration and neointimal hyperplasia2013

    • Author(s)
      Ashino T, Yamamoto M, Yoshida T, Numazawa S
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 33 Issue: 4 Pages: 760-768

    • DOI

      10.1161/atvbaha.112.300614

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590143, KAKENHI-PROJECT-23659068, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24790785
  • [Journal Article] The Gatal 5' region harbors distinct cis-regulatory modules that direct gene activation in erythroid cells and gene inactivation in HSCs2013

    • Author(s)
      Takai J, Moriguchi T, Suzuki M, Yu L, Ohneda K, and Yamamoto M.
    • Journal Title

      Blood.

      Volume: 122 Issue: 20 Pages: 3450-3460

    • DOI

      10.1182/blood-2013-01-476911

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06534, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118722
  • [Journal Article] NF-E2 p45 is important for establishing normal function of platelets.2013

    • Author(s)
      Fujita R, Takayama-Tsujimoto M, Satoh H, Gutiérrez L, Aburatani H, Fujii S, Sarai A, Bresnick EH, Yamamoto M*, and Motohashi H* (* corresponding authors)
    • Journal Title

      Mol Cell Biol

      Volume: 33 Issue: 14 Pages: 2659-2670

    • DOI

      10.1128/mcb.01274-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24659142
  • [Journal Article] Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling2013

    • Author(s)
      Guiu J, Shimizu R. D'Altri T,Fraser ST, Hatakeyama J, Bresnick EH, Kageyama R, Dzierzak E, Yamamoto M, Espinosa L, Bigas A.
    • Journal Title

      J Exp Med

      Volume: 210(1) Issue: 1 Pages: 71-84

    • DOI

      10.1084/jem.20120993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] Nrf2 deficiency leads to behavioral, neurochemical and transcriptional changes in mice2013

    • Author(s)
      Muramatsu H, Katsuoka F, Toide K, Shimizu Y, Furusako S, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 18 Issue: 10 Pages: 899-908

    • DOI

      10.1111/gtc.12083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding2013

    • Author(s)
      More VR, Xu J, Shimpi PC, Belgrave C, Luyendyk JP, Yamamoto M, Slitt AL
    • Journal Title

      Free Radic Biol Med

      Volume: 61C Pages: 85-94

    • DOI

      10.1016/j.freeradbiomed.2013.03.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] GATA factor switching from GATA2 to GATA1 contributes to erythroid differentiation2013

    • Author(s)
      Suzuki M, Kobayashi-Osaki M, Tsutsumi S, Pan X, Ohmori S, Takai J, Moriguchi T, Ohneda O, Ohneda K, Shimizu R, Kanki Y, Kodama T, Aburatani H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 18 Issue: 11 Pages: 921-933

    • DOI

      10.1111/gtc.12086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24590359, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24710227, KAKENHI-PROJECT-24790957, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25118722, KAKENHI-PUBLICLY-25125707, KAKENHI-PROJECT-25440007, KAKENHI-PROJECT-25860221
  • [Journal Article] Naturally occurring oncogenic GATA1 mutants with internal deletions in transient abnormal myelopoiesis in Down syndrome2013

    • Author(s)
      Toki T, Kanezaki R, Kobayashi E, Kaneko H, Suzuki M, Wang R, Terui K, Kanegane H, Maeda M, Endo M, Mizuochi T, Adachi S, Hayashi Y, Yamamoto M, Shimizu R, Ito E.
    • Journal Title

      Blood

      Volume: 121(16) Issue: 16 Pages: 3181-3184

    • DOI

      10.1182/blood-2012-01-405746

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23390266, KAKENHI-PROJECT-23390273, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24790957, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-25670482, KAKENHI-PUBLICLY-23118501
  • [Journal Article] Roles of Keap1-Nrf2 system in upper aerodigestive tract carcinogenesis2013

    • Author(s)
      Ohkoshi A, Suzuki T, Ono M, Kobayashi T, Yamamoto M
    • Journal Title

      Cancer Prev Res

      Volume: 6 Pages: 149-159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Disruption of the hbsll-myb locus causes hereditary persistence of fetal hemoglobin in a mouse model.2013

    • Author(s)
      Suzuki M, Yamazaki H, Mukai HY, Motohashi H, Shi L, Tanabe 0, Engel JD, Yamamoto M.
    • Journal Title

      Molecular and Cellular Biology

      Volume: 33 Issue: 8 Pages: 1687-1695

    • DOI

      10.1128/mcb.01617-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08044, KAKENHI-PLANNED-23116002, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790957
  • [Journal Article] Mature erythrocyte membrane homeostasis is compromised by lass of the GATA1-FOG1 interaction2012

    • Author(s)
      Hasegawa A, Shimizu R, Mohandas N, Yamamoto M
    • Journal Title

      Blood

      Volume: 11 Pages: 2615-2623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] がん細胞におけるKeap1-Nrf2システムの破綻2012

    • Author(s)
      藤田理恵,本橋ほづみ,山本雅之
    • Journal Title

      実験医学

      Volume: 30 Pages: 2814-2821

    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Pathophysiological regulation of cellular stress response by Keap1-Nrf2 system2012

    • Author(s)
      Yamamoto M
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 52 Pages: 861-861

    • NAID

      130004505186

    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2-MafG heterodimers contribute globally to antioxidant and metabolic networks2012

    • Author(s)
      Hirotsu Y, Katsuoka F, Funayama R, Nagashima T, Nishida Y, Nakayama K, Engel JD, Yamamoto M.
    • Journal Title

      Nucleic Acids Res.

      Volume: 40 Issue: 20 Pages: 10228-10239

    • DOI

      10.1093/nar/gks827

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07842, KAKENHI-PROJECT-23790351, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24700951
  • [Journal Article] Heme and heme biosynthesis intermediates induce Heme oxygenase-1 and Cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: Different requirement for transcription factor Nuclear factor erythroid-derived 2-like 22012

    • Author(s)
      Lämsä V, Levonen AL, Sormunen R, Yamamoto M, Hakkola J
    • Journal Title

      Toxicol Sci

      Volume: 130 Issue: 1 Pages: 132-144

    • DOI

      10.1093/toxsci/kfs237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Targeted deletion of Nrf2 impairs lung development and oxidant injury in neonatal mice2012

    • Author(s)
      Cho HY, van Houten B, Wang X, Miller-Degraff L, Fostel J, Gladwell W, Perrow L, Panduri V, Kobzik L, Yamamoto M, Bell DA, and Kleeberger SR
    • Journal Title

      Antioxid Redox Signal

      Volume: 17 Issue: 8 Pages: 1066-1082

    • DOI

      10.1089/ars.2011.4288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Genetic evidence of an evolutionarily conserved role for Nrf2 in the protection against oxidative stress2012

    • Author(s)
      Mukaigasa K, Nguyen LT, Li L, Nakajima H, Yamamoto M, and Kobayashi M
    • Journal Title

      Mol Cell Biol

      Volume: 32 Issue: 21 Pages: 4455-4461

    • DOI

      10.1128/mcb.00481-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] The contribution of GATA1 dysfunction to multi-step leukemogenesis2012

    • Author(s)
      Shimizu R, Yamamoto M
    • Journal Title

      Cancer Sci

      Volume: 103(12) Issue: 12 Pages: 2039-2044

    • DOI

      10.1111/cas.12007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012

    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
    • Journal Title

      Cancer Sci

      Volume: 103 Issue: 4 Pages: 760-766

    • DOI

      10.1111/j.1349-7006.2012.02216.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24790306, KAKENHI-PLANNED-23116002
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J.Gastroenterol

      Volume: (印刷中) Issue: 8 Pages: 924-935

    • DOI

      10.1007/s00535-012-0552-9

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22300260, KAKENHI-PROJECT-22500656, KAKENHI-PROJECT-22590802, KAKENHI-PROJECT-22790127, KAKENHI-PROJECT-23300250, KAKENHI-PROJECT-23660033, KAKENHI-PROJECT-24650436, KAKENHI-PROJECT-24659104, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Highly Potent Activation of Nrf2 by Topical Tricyclic Bis (Cyano Enone): Implications for Protection against UV Radiation during Thiopurine Therapy2012

    • Author(s)
      Kalra S, Knatko EV, Zhang Y, Honda T, Yamamoto M, and Dinkova-Kostova AT
    • Journal Title

      Cancer Prev Res

      Volume: 5 Issue: 7 Pages: 973-981

    • DOI

      10.1158/1940-6207.capr-12-0041

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation2012

    • Author(s)
      Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami KI, Morito N, Takahashi S, Maher JM, Yamamoto M, Itoh K
    • Journal Title

      Free Radic Biol Med

      Volume: 53 Issue: 12 Pages: 2256-2262

    • DOI

      10.1016/j.freeradbiomed.2012.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24591223, KAKENHI-PROJECT-24659122, KAKENHI-PROJECT-24790305
  • [Journal Article] The regulation of GATA factor expression is distinct between erythroid and mast cell lineages2012

    • Author(s)
      Ohmori S, Takai J, Ishijima Y, Suzuki M, Moriguchi T, Philipsen S, Yamamoto M, and Ohneda K
    • Journal Title

      Mol Cell Biol

      Volume: 32(23) Pages: 4742-4755

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Journal Article] Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma2012

    • Author(s)
      Inoue D, Suzuki T, Mitsuishi Y, Miki Y, Suzuki S, Sugawara S, Watanabe M, Sakurada A, Endo C, Uruno A, Sasano H, Nakagawa T, Satoh K, Tanaka N, Kubo H, Motohashi H, Yamamoto M
    • Journal Title

      Cancer Sci

      Volume: 103(4) Pages: 760-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22890014
  • [Journal Article] N- and C-terminal transactivation domains of GATA1 protein coordinate hematopoietic program2012

    • Author(s)
      Kaneko H, Kobayashi E, Yamamoto M, Shimizu R
    • Journal Title

      J Biol Chem

      Volume: 287(25) Issue: 25 Pages: 21439-21449

    • DOI

      10.1074/jbc.m112.370437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456, KAKENHI-PROJECT-24890015
  • [Journal Article] Embryonic lethality and fetal liver apoptosis in mice lacking all three small Maf proteins2012

    • Author(s)
      Yamazaki H, Katsuoka F, Motohashi H, Engel JD, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 32 Issue: 4 Pages: 808-816

    • DOI

      10.1128/mcb.06543-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390074, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-23790351
  • [Journal Article] Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus2012

    • Author(s)
      Chen H, Li J, Li H, Hu Y, Tevebaugh W, Yamamoto M, Que J, and Chen X
    • Journal Title

      PLoS One

      Volume: 7 Issue: 5 Pages: e36504-e36504

    • DOI

      10.1371/journal.pone.0036504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming.2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M*, and Motohashi H*.
    • Journal Title

      Cancer Cell

      Volume: 22 Issue: 1 Pages: 66-79

    • DOI

      10.1016/j.ccr.2012.05.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249015, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Nuclearfactorerythroid-derivedfactor2-relatedfactor2regulatestranscription of CCAAT/enhancer-bindingprotein β during adipogenesis2012

    • Author(s)
      Hou Y, Xue P, Bai Y, Liu D, Woods CG, Yarborough K, Fu J, Zhang Q, Sun G, Collins S, Chan JY, Yamamoto M, Andersen ME, Pi J
    • Journal Title

      Free Radic Biol Med

      Volume: 52 Issue: 2 Pages: 462-473

    • DOI

      10.1016/j.freeradbiomed.2011.10.453

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H, Yamamoto M and Motohashi H
    • Journal Title

      Cancer Cell

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice2012

    • Author(s)
      Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M.
    • Journal Title

      Molecular and Cellular Biology

      Volume: 32 Issue: 12 Pages: 2312-2322

    • DOI

      10.1128/mcb.06699-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-24590371, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] Analysis of the role of Nrf2 in the expression of liver proteins in mice using two-dimensional gel-based proteomics2012

    • Author(s)
      Abdullah A, Kitteringham NR, Jenkins RE, Goldring C, Higgins L, Yamamoto M, Hayes J, and Park BK
    • Journal Title

      Pharmacol Rep

      Volume: 64 Pages: 680-697

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] The Keap1-Nrf2 system in cancers: Stress response and anabolic metabolism.2012

    • Author(s)
      Mitsuishi Y, Motohashi H*, and Yamamoto M*
    • Journal Title

      Front. Oncol.

      Volume: 2 Pages: 200-200

    • DOI

      10.3389/fonc.2012.00200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PLANNED-23116002
  • [Journal Article] Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuates dopaminergic neurotoxicity in the MPTP- mouse model of Parkinson's disease2012

    • Author(s)
      Kaidery NA, Banerjee R, Yang L, Smirnova NA, Hushpulian DM, Liby KT, Williams CR, Yamamoto M, Kensler TW, Ratan RR, Sporn MB, Beal MF, Gazaryan IG, and Thomas B
    • Journal Title

      Antioxid Redox Signal

      Volume: 18 Issue: 2 Pages: 139-157

    • DOI

      10.1089/ars.2011.4491

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] Keap1 degradation by autophagy for the maintenance of redox homeostasis2012

    • Author(s)
      Taguchi K, Fujikawa N, Komatsu M, Ishii T, Unno M, Akaike T, Motohashi H, and Yamamoto M
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 109 Issue: 34 Pages: 13561-13566

    • DOI

      10.1073/pnas.1121572109

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PROJECT-24790307, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-23116002, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction2012

    • Author(s)
      Hasegawa A, Shimizu R, Mohandas N, Yamamoto M.
    • Journal Title

      Blood

      Volume: 119 Pages: 2615-2623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.2012

    • Author(s)
      Takaya K, Suzuki T, Motohashi H, Onodera K, Satomi S, Kensler TW and Yamamoto M.
    • Journal Title

      Free Rad Biol Med

      Volume: 53 Issue: 4 Pages: 817-827

    • DOI

      10.1016/j.freeradbiomed.2012.06.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659166, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24390075, KAKENHI-PUBLICLY-23112502, KAKENHI-PLANNED-23116002
  • [Journal Article] Mature erythrocyte membrane homeostasis is compromised by loss of the GATA1-FOG1 interaction2012

    • Author(s)
      Hasegawa A, Shimizu R, Mohandas N, Yamamoto M
    • Journal Title

      Blood

      Volume: 119(11) Issue: 11 Pages: 2615-2623

    • DOI

      10.1182/blood-2011-09-382473

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390288, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24659142, KAKENHI-PROJECT-24659456
  • [Journal Article] Nrf2 in bone marrow-derived cells positively contributes to the advanced stage of atherosclerotic plaque formation2012

    • Author(s)
      Harada N, Ito K, Hosoya T, Mimura J, Maruyama A, Noguchi N, Yagami KI, Morito N, Takahashi S, Maher JM, Yamamoto M, Itoh K
    • Journal Title

      Free Radic Biol Med

      Volume: 53 Issue: 2 Pages: 2256-2262

    • DOI

      10.1158/1940-6207.capr-12-0401-t

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Journal Article] NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1β Genes2012

    • Author(s)
      Hirotsu Y, Hataya N, Katsuoka F, Yamamoto M.
    • Journal Title

      Mol Cell Biol.

      Volume: 32 Issue: 14 Pages: 2760-2770

    • DOI

      10.1128/mcb.06706-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07842, KAKENHI-PROJECT-23790351, KAKENHI-PROJECT-24249015
  • [Journal Article] Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation2012

    • Author(s)
      Xue M, Rabbani N, Momiji H, Imbasi P, Anwar MM, Kitteringham N, Park BK, Souma T, Moriguchi T, Yamamoto M, Thornalley PJ.
    • Journal Title

      Biochemical Journal

      Volume: 443 Issue: 1 Pages: 213-222

    • DOI

      10.1042/bj20111648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J07924, KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590260, KAKENHI-PROJECT-24590371
  • [Journal Article] Nrf2 inhibits hepatic iron accumulation and counteracts oxidative stress-induced liver injury in nutritional steatohepatitis2012

    • Author(s)
      Okada K, Warabi E, Sugimoto H, Horie M, Tokushige K, Ueda T, Harada N, Taguchi K, Hashimoto E, Itoh K, Ishii T, Utsunomiya H, Yamamoto M, Shoda J
    • Journal Title

      J Gastroenterol

      Volume: (In press)

    • NAID

      10031051379

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Journal Article] Isolation and Characterization of Renal Erythropoietin-Producing Cells from Genetically Produced Anemia Mice2011

    • Author(s)
      Pan X, Suzuki N, Hirano I, Yamazaki S, Minegishi N, Yamamoto M
    • Journal Title

      PLoS ONE

      Volume: 6 Issue: 10 Pages: 25839-25839

    • DOI

      10.1371/journal.pone.0025839

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J06108, KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002
  • [Journal Article] Constitutive activation of nuclear factor-E2-related factor 2 induces biotransformation enzyme and transporter expression in livers of mice with hepatocyte-specific deletion of Kelch-like ECH-associated protein 12011

    • Author(s)
      Cheng Q, Taguchi K, Aleksunes LM, Manautou JE, Cherrington NJ, Yamamoto M, Slitt AL
    • Journal Title

      J Biochem Mol Toxicol

      Volume: 25 Issue: 5 Pages: 320-329

    • DOI

      10.1002/jbt.20392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Discovery of the negative regulator of Nrf2, Keapl: A historical overview.2011

    • Author(s)
      Itch K, Mimura J, Yamamoto M.
    • Journal Title

      Antioxid Redox Signal

      Volume: 13 Pages: 1665-1678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Metabolism and tissue distribution of sulforaphane in Nrf2 knockout and wild-type mice2011

    • Author(s)
      Clarke JD, Hsu A, Williams DE, Dashwood RH, Stevens JF, Yamamoto M, Ho E
    • Journal Title

      Pharm Res

      Volume: 28 Issue: 12 Pages: 3171-3179

    • DOI

      10.1007/s11095-011-0500-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 degron-fused reporter system ; a new tool for specific evaluation of Nrf2 inducers.2011

    • Author(s)
      Yosuke Hirotsu, Fumiki Katsuoka, Ken Itoh, Masayuki Yamamoto.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 406-415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Protein aggregation, not polyubiquitin conjugation, serves as a signal forselective autophagy.2011

    • Author(s)
      Riley BE, Kaiser SE, Shaler TA, Ham T, Hipp MS, Sofos E, Ng ACY, Lage K, Xavier RJ, Ryu K-Y, Yamamoto M, Ishii T, Tanaka K, Mizushima N, Komatsu M, Kopito RR.
    • Journal Title

      J Cell Biol

      Volume: 191 Pages: 537-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Nrf2 degron-fused reporter system : a new tool for specific evaluation of Nrf2 inducers2011

    • Author(s)
      Hirotsu Y, Katsuoka F, Itoh K, and Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 406-415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia.2011

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M.
    • Journal Title

      Blood

      Volume: 117 Pages: 986-996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Differential Modulation of Keratin Expression by Sulforaphane Occurs via Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia2011

    • Author(s)
      Kerns M, Depianto D, Yamamoto M, Coulombe PA
    • Journal Title

      Mol Biol Cell

      Volume: 23 Pages: 4068-4057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of Nrf2 in host defense against influenza virus in cigarette smoke-exposed mice2011

    • Author(s)
      Yageta Y, Ishii Y, Morishima Y, Masuko H, Ano S, Yamadori T, Itoh K, Takeuchi K, Yamamoto M, Hizawa N
    • Journal Title

      J Virol

      Volume: 85 Issue: 10 Pages: 4679-4690

    • DOI

      10.1128/jvi.02456-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
  • [Journal Article] Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia.2011

    • Author(s)
      Kerns M, Depianto D, YamamotoM, Coulombe PA.
    • Journal Title

      Mol Biol Cell

      Volume: 23 Pages: 4068-4057

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells2011

    • Author(s)
      Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Ando J, Iwadate M, Yamamoto M, Lee MS, Tanaka K, Komatsu M
    • Journal Title

      J Cell Biol

      Volume: 193 Issue: 2 Pages: 275-284

    • DOI

      10.1083/jcb.201102031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390234, KAKENHI-PROJECT-21659045, KAKENHI-PROJECT-22650091
  • [Journal Article] Possible Involvement of Oxidative Stress in 5-Fluorouracil-Mediated Myelosuppression in Mice2011

    • Author(s)
      Numazawa S, Sugihara K, Miyake S, Tomiyama H, Hida A, Hatsuno M, Yamamoto M, Yoshida T
    • Journal Title

      Basic Clin Pharmacol Toxicol

      Volume: 108 Pages: 40-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia2011

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M.
    • Journal Title

      Blood

      Volume: 177 Pages: 986-996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes2011

    • Author(s)
      Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, and Itoh K.
    • Journal Title

      J Biochem

      Volume: 150 Pages: 209-217

    • NAID

      10030587033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Possible involvement of oxidative stress in 5-fluorouracil-mediated myelosuppression in mice2011

    • Author(s)
      Numazawa S, Sugihara K, Miyake S, Tomiyama H, Hida A, Hatsuno M, Yamamoto M, Yoshida T
    • Journal Title

      Basic Clin Pharmacol Toxicol

      Volume: 108 Issue: 1 Pages: 40-45

    • DOI

      10.1111/j.1742-7843.2010.00621.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590143
  • [Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia2011

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M
    • Journal Title

      Blood

      Volume: 117 Issue: 3 Pages: 986-996

    • DOI

      10.1182/blood-2010-05-285817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216
  • [Journal Article] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2011

    • Author(s)
      Souma T, Abe M, Moriguchi T, Yanagisawa-Miyazawa N, Shibata E, Akiyama Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
    • Journal Title

      J Am Soc Nephrol

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Acceleration of UVB-induced photoageing in nrf2 gene-deficient mice2011

    • Author(s)
      Hirota A, Kawachi Y, Yamamoto M, Koga T, Hamada K, Otsuka F
    • Journal Title

      Exp Dermatol

      Volume: 20 Issue: 8 Pages: 664-668

    • DOI

      10.1111/j.1600-0625.2011.01292.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591454
  • [Journal Article] Dysfunction of fibroblasts of extra-renal origin underlies renal fibrosis and renal anemia in mice2011

    • Author(s)
      Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K-i, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M
    • Journal Title

      J Clin Invest

      Volume: 121 Issue: 10 Pages: 3981-3990

    • DOI

      10.1172/jci57301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591027, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22600011
  • [Journal Article] Specific contribution of the Erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stage2011

    • Author(s)
      Suzuki N, Obara N, Pan X, Watanabe M, Jishage K, Minegishi N, and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 3896-3905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Association of Keap1 and Nrf2 genetic mutations and polymorphisms with endometrioid endometrial adenocarcinoma survival2011

    • Author(s)
      Wong TF, Yoshinaga K, Monma Y, Ito K, Niikura H, Nagase S, Yamamoto M, Yaegashi N
    • Journal Title

      Int J Gynecol Cancer

      Volume: 21 Issue: 8 Pages: 1428-1435

    • DOI

      10.1097/igc.0b013e31822d0eb2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21592119, KAKENHI-PROJECT-23592431
  • [Journal Article] Molecular determinants for small Maf protein control of platelet production2011

    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Issue: 1 Pages: 151-162

    • DOI

      10.1128/mcb.00798-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Acute erythropoietin cardioprotection is mediated by endothelial response2011

    • Author(s)
      Teng R, Calvert JW, Sibmooh N, Piknova B, Suzuki N, Sun J, Martinez K, Yamamoto M, Schechter AN, Lefer DJ, Noguchi CT
    • Journal Title

      Basic Res Cardiol

      Volume: 106 Issue: 3 Pages: 343-354

    • DOI

      10.1007/s00395-011-0158-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 and selenoproteins are essential for maintaining oxidative homeostasis in erythrocytes and protecting against hemolytic anemia2011

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M
    • Journal Title

      Blood

      Volume: 117 Pages: 986-996

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Discovery of the negative regulator of Nrf2, Keap1 : A historical overview2011

    • Author(s)
      Itoh K, Mimura J, Yamamoto M
    • Journal Title

      Antioxid Redox Signal

      Volume: 13 Pages: 1665-1678

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness2011

    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 405 Issue: 1 Pages: 13-18

    • DOI

      10.1016/j.bbrc.2010.12.092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PROJECT-22390163
  • [Journal Article] Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 Cysteine 151-independent mechanism2011

    • Author(s)
      Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Yla-Herttuala S, Freeman BA, Levonen AL
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 16 Pages: 14019-14027

    • DOI

      10.1074/jbc.m110.190710

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system : a study using green fluorescent protein transgenic zebrafish2011

    • Author(s)
      Tsujita T, Li L, Nakajima H, Iwamoto N, Nakajima-Takagi Y, Ohashi K, Kawakami K, Kumagai Y, Freeman BA, Yamamoto M, Kobayashi M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 1 Pages: 46-57

    • DOI

      10.1111/j.1365-2443.2010.01466.x

    • NAID

      120007130821

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21659043
  • [Journal Article] CD36 participates in a signaling pathway that regulates ROS formation in murine VSMC2011

    • Author(s)
      Li W, Febbraio M, Reddy SP, Yu D-Y, Yamamoto M, Silverstein RL
    • Journal Title

      J Clin Invest

      Volume: 120 Pages: 3996-4006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Possible Involvement of Oxidative Stress in 5-Fluorouracil-Mediated Myelosuppression in Mice.2011

    • Author(s)
      Numazawa S, Sugihara K, Miyake S, Tomiyama H, Hida A, HatsunoM, Yamamoto M, Yoshida T.
    • Journal Title

      Basic Clin Pharmacol Toxicol.

      Volume: 108 Pages: 40-45

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells2011

    • Author(s)
      Sugiyama, H., Onuki, K., Ishige, K., Baba, N., Ueda, T., Matsuda, S., Takeuchi, K., Onodera, M., Nakanuma, Y., Yamato, M., Yamamoto, M., Hyodo, I., Shoda, J
    • Journal Title

      J Gastroenterol

      Volume: 46 Pages: 779-789

    • NAID

      10029029679

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Journal Article] Luminal alkalization attenuates superoxide production induced by fattyacid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways.2011

    • Author(s)
      Souma T, Abe M, Moriguchi T, Yanagisawa-MiyazawaN, Shibata E, Akiyama Y, Toyohara T, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S.
    • Journal Title

      J Am See Nephrol

      Volume: 22 Pages: 635-648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction2011

    • Author(s)
      Kobayashi A, Tsukide T, Miyasaka T, Morita T, Mizoroki T, Saito Y, Ihara Y, Takashima A, Noguchi N, Fukamizu A, Hirotsu Y, Ohtsuji M, Katsuoka F, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 6 Pages: 692-703

    • DOI

      10.1111/j.1365-2443.2011.01522.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590277
  • [Journal Article] CD36 participates in a signaling pathway that regulates ROS formation inmurine VSMC.2011

    • Author(s)
      Li W, Febbraio M, Reddy SP, Yu D-Y, Yamamoto M, Silverstein RL.
    • Journal Title

      J Clin Invest

      Volume: 120 Pages: 3996-4006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Protein aggregation, not polyubiquitin conjugation, serves as a signal for selective autophagy2011

    • Author(s)
      Riley BE, Kaiser SE, Shaler TA, Hara T, Hipp MS, Sofos E, Ng ACY, Lage K, Xavier RJ, Ryu K-Y, Yamamoto M, Ishii T, Tanaka K, Mizushima N, Komatsu M, Kopito RR
    • Journal Title

      J Cell Biol

      Volume: 191 Pages: 537-552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Disrupted erythropoietin signaling promotes obesity and alters hypothalamus proopiomelanocortin production2011

    • Author(s)
      Teng R, Gavrilova O, Suzuki N, Chanturiya T, Schimel D, Hugendubler L, Mammen S, Yver DR, Cushman SW, Mueller E, Yamamoto M, Hsu LL, Noguchi CT
    • Journal Title

      Nature Commun

      Volume: 2 Issue: 1

    • DOI

      10.1038/ncomms1526

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Up-regulation of p27kip1 contributes to Nrf2-mediated protection against angiotensin II-induced cardiac hypertrophy2011

    • Author(s)
      Li J, Zhang C, Xing Y, Janicki JS, Yamamoto M, Wang XL, Tang DQ, Cui T
    • Journal Title

      Cardiovasc Res

      Volume: 90 Issue: 2 Pages: 315-324

    • DOI

      10.1093/cvr/cvr010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution2011

    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 2 Pages: 123-140

    • DOI

      10.1111/j.1365-2443.2010.01473.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes2011

    • Author(s)
      Mimura J, Kosaka K, Maruyama A, Satoh T, Harada N, Yoshida H, Satoh K, Yamamoto M, Itoh K
    • Journal Title

      J Biochem

      Volume: 150 Issue: 2 Pages: 209-217

    • DOI

      10.1093/jb/mvr065

    • NAID

      10030587033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-22790304, KAKENHI-PROJECT-23592081, KAKENHI-PROJECT-23790319
  • [Journal Article] Dual Regulation of the Transcriptional Activity of Nrf1 by β-TrCP-and Hrd1-Dependent Degradation Mechanisms2011

    • Author(s)
      Tsuchiya Y, Morita T, Kim M, Iemura SI, Natsume T, Yamamoto M, Kobayashi A
    • Journal Title

      Mol Cell Biol

      Volume: 31 Issue: 22 Pages: 4500-4512

    • DOI

      10.1128/mcb.05663-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590277, KAKENHI-PROJECT-22790329
  • [Journal Article] Molecular determinants for small Maf protein control of platelet production.2011

    • Author(s)
      Motohashi H, Fujita R, Takayama M, Inoue A, Katsuoka F, Bresnick EH, Yamamoto M.Molecular determinants for small Maf protein control of platelet production.
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 151-162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice2011

    • Author(s)
      Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M.
    • Journal Title

      J Clin Invest

      Volume: 121 Pages: 3980-3981

    • NAID

      120003338854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Transcription factor Nrf2 maintains the basa1 expression of Mdm2 : An implication of the regulation of p53 signaling by Nrf22011

    • Author(s)
      You A, Nam CW, Wakabayashi N, Yamamoto M, Kensler TW, Kwak MK
    • Journal Title

      Arch Biochem Biophys

      Volume: 507 Issue: 2 Pages: 356-364

    • DOI

      10.1016/j.abb.2010.12.034

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction2011

    • Author(s)
      Akira Kobayashi, Takako Tsukide, Tomohiro Miyasaka, Tomoko Morita, Tatsuya Mizoroki, Yoshiro Saito, Yasuo Ihara, Akihiko Takashima, Noriko Noguchi, Akiyoshi Fukamizu, Yosuke Hirotsu, Makiko Ohtsuji, Fumiki Katsuoka, Masayuki Yamamoto
    • Journal Title

      Genes Cells

      Volume: (未定)(印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Dual regulation of the transcriptional activity of Nrf1 by { beta}-TrCP-and Hrd1-dependent degradation mechanisms2011

    • Author(s)
      Tsuchiya Y, Morita T, Kim M, Iemura SI, Natsume T, Yamamoto M, and Kobayashi A.
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 4500-4512

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Nrf2 is essential for cholesterol crystal-induced inflammasome activation and exacerbation of atherosclerosis2011

    • Author(s)
      Freigang S, Ampenberger F, Spohn G, Heer S, Shamshiev AT, Kisielow J, Hersberger M, Yamamoto M, Bachmann MF, Kopf M
    • Journal Title

      Eur J Immunol

      Volume: 41 Issue: 7 Pages: 2040-2051

    • DOI

      10.1002/eji.201041316

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Hirotsu Y, Katsuoka F, Itoh K, and Yamamoto M. Nrf2 degron-fused reporter system : a new tool for specific evaluation of Nrf2 inducers2011

    • Author(s)
      Hirotsu Y, Katsuoka F, Itoh K, and Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 406-415

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] Targeted deletion of Nrf2 reduces urethane-induced lung tumor development in mice2011

    • Author(s)
      Bauer AK, Cho HY, Miller-Degraff L, Walker C, Helms K, Fostel J, Yamamoto M, Kleeberger SR
    • Journal Title

      PLoS One

      Volume: 6 Issue: 10 Pages: e26590-e26590

    • DOI

      10.1371/journal.pone.0026590

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011

    • Author(s)
      Suzuki T, Maher JM, and Yamamoto M
    • Journal Title

      Cancer Res

      Volume: 71 Pages: 1700-1709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keapl-Nrf2 system : study using GFP transgenic zebrafish.2011

    • Author(s)
      Tsujita T, Li L, Nakajima H, Nakajima-Takagi Y, Kawakami K, Freeman B, Yamamoto M, Kobayashi M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 46-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Nitro-fatty acids and cyclopentenone prostaglandins share strategies to activate the Keap1-Nrf2 system : study using GFP transgenic zebrafish2011

    • Author(s)
      Tsujita T, Li L, Nakajima H, Nakajima-Takagi Y, Kawakami K, Freeman B, Yamamoto M, Kobayashi M
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 46-57

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.2011

    • Author(s)
      Inoue D, Kubo H, Taguchi K, Suzuki T, Komatsu M, Motohashi H, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Common

      Volume: 405 Pages: 13-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury2011

    • Author(s)
      Toyama T, Shinkai Y, Yasutake A, Uchida K, Yamamoto M, Kumagai Y
    • Journal Title

      Environ Health Perspect

      Volume: 119 Issue: 8 Pages: 1117-1122

    • DOI

      10.1289/ehp.1003123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22790128
  • [Journal Article] Protective role of Nrf2 in gage-related hearing loss and gentamicin ototoxicity2011

    • Author(s)
      Hoshino T, Tabuchi K, Nishimura B, Tanaka S, Nakayama M, Ishii T, Warabi E, Yanagawa T, Shimizu R, Yamamoto M, Hara A
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 415 Issue: 1 Pages: 94-98

    • DOI

      10.1016/j.bbrc.2011.10.019

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21390288
  • [Journal Article] Nrf2 degron-fused reporter system ; a new tool for specific evaluation of Nrf2 inducers2011

    • Author(s)
      Hirotsu Y, Katsuoka F, Itoh K, Yamamoto M
    • Journal Title

      Genes Cells

      Volume: 16 Issue: 4 Pages: 406-415

    • DOI

      10.1111/j.1365-2443.2011.01496.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010
  • [Journal Article] Tissue-restricted expression of Nrf2 and its target genes in zebrafish with gene-specific variations in the induction profiles2011

    • Author(s)
      Nakajima H, Nakajima-Takagi Y, Tsujita T, Akiyama S, Wakasa T, Mukaigasa K, Kaneko H, Tamaru Y, Yamamoto M, Kobayashi M
    • Journal Title

      PLoS One

      Volume: 6 Issue: 10 Pages: e26884-e26884

    • DOI

      10.1371/journal.pone.0026884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21659043
  • [Journal Article] Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction.2011

    • Author(s)
      Akira Kobayashi, Takako Tsukide, Tomohiro Miyasaka, Tomoko Morita, Tatsuya Mizoroki, Yoshiro Saito, Yasuo Ihara, Akihiko Takashima, Noriko Noguchi, Akiyoshi Fukamizu, Yosuke Hirotsu, Makiko Ohtsuji, Fumiki Katsuoka, Masayuki Yamamoto.
    • Journal Title

      Genes Cells

      Volume: 印刷中(未定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Antioxidant signaling via Nrf2 counteracts lipopolysaccharide-mediated inflammatory responses in foam cell macrophages2011

    • Author(s)
      Kuhn AM, Tzieply N, Schmidt MV, von Knethen A, Namgaladze D, Yamamoto M, Brane B
    • Journal Title

      Free Radic Biol Med

      Volume: 50 Issue: 10 Pages: 1382-1391

    • DOI

      10.1016/j.freeradbiomed.2011.02.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Molecular mechanisms of the Keapl-Nrf2 pathway in stress response and cancer evolution.2011

    • Author(s)
      Taguchi K, Motohashi H, Yamamoto M.
    • Journal Title

      Genes Cells

      Volume: 16 Pages: 123-140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Isolation and Characterization of renal erythropoietin-producing cells from genetically produced anemia mice2011

    • Author(s)
      Pan X, Suzuki N, Hirano I, Yamazaki S, Minegishi N, and Yamamoto M
    • Journal Title

      PLos One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 regulates ferroportin 1-mediated iron efflux and counteracts lipopolysaccharide-induced ferroportin-1 mRNA suppression in macrophages2011

    • Author(s)
      Harada N, Kanayama M, Maruyama A, Yoshida A, Tazumi K, Hosoya T, Mimura J, Toki T, Maher JM, Yamamoto M, Itoh K
    • Journal Title

      Arch Biochem Biophys

      Volume: 508 Issue: 1 Pages: 101-109

    • DOI

      10.1016/j.abb.2011.02.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PLANNED-20117010, KAKENHI-PROJECT-23790319
  • [Journal Article] The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice2011

    • Author(s)
      Tatsumi, K., Yamamoto-Mukai, H., Shimizu, R., Waguri, S., Sou, Y-S., Sakamoto, A., Taya, C., Shitara, H., Hara, T., Chung, C.H., Tanana, K., Yamamoto, M., Komatsu, M.
    • Journal Title

      Nat.Commun.

      Volume: 2 Issue: 1 Pages: 181-181

    • DOI

      10.1038/ncomms1182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21000012, KAKENHI-PROJECT-21390288, KAKENHI-PROJECT-23659167
  • [Journal Article] Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages2011

    • Author(s)
      Suzuki N, Obara N, Pan X, Watanabe M, Jishage K-i, Minegishi N, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 31 Issue: 18 Pages: 3896-3905

    • DOI

      10.1128/mcb.05463-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-21591216, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22790895
  • [Journal Article] Initial response and cellular protection through the Keap1/Nrf2 system during exposure of primary mouse hepatocytes to 1,2-naphthoquinone2011

    • Author(s)
      Miura T, Shinkai Y, Jiang HY, Iwamoto N, Sumi D, Taguchi K, Yamamoto M, Jinno H, Tanaka-Kagawa T, Cho AK, Kumagai Y
    • Journal Title

      Chem Res Toxicol

      Volume: 24 Issue: 4 Pages: 559-567

    • DOI

      10.1021/tx100427p

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22406004, KAKENHI-PROJECT-22790127, KAKENHI-PUBLICLY-23117503
  • [Journal Article] The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice2011

    • Author(s)
      Tatsumi K, Yamamoto-Mukai H, Shimizu R, Waguri S, Sou Y-S, Sakamoto A, Taya C, Shitara H, Hara T, Chung CH, Tanaka K, Yamamoto M, Komatsu M
    • Journal Title

      Nature Commun

      Volume: 2 Pages: 181-181

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer2011

    • Author(s)
      Shibata T, Kokubu A, Saito S, Narisawa-Saito M, Sasaki H, Aoyagi K, Yoshimatsu Y, Tachimori Y, Kushima R, Kiyono T, Yamamoto M
    • Journal Title

      Neoplasia

      Volume: 13 Issue: 9 Pages: 864-873

    • DOI

      10.1593/neo.11750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Oral azathioprine leads to higher incorporation of 6-thioguanine in DNA of skin than liver : The protective role of the Keap1/Nrf2/ARE pathway2011

    • Author(s)
      Kalra S, Zhang Y, Knatko EV, Finlayson S, Yamamoto M, Dinkova-Kostova AT
    • Journal Title

      Cancer Prev Res

      Volume: 4 Issue: 10 Pages: 1665-1674

    • DOI

      10.1158/1940-6207.capr-11-0137

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages2011

    • Author(s)
      Suzuki N, Obara N, Pan X, Watanabe M, Jishage K, Minegishi N, and Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 31 Pages: 3896-3905

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Journal Article] The transcriptome of Nrf2^<-/-> Mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
    • Journal Title

      Tox Sci

      Volume: 115 Pages: 238-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Deletion of Nuclear Factor-E2-Related Factor-2 Leads to Rapid Onset and Progression of Nutritional Steatohepatitis in Mice2010

    • Author(s)
      Sugimoto H, Okada K, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M.
    • Journal Title

      Am J Physiol Gastrointest Liver Physiol 298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010

    • Author(s)
      Taguchi K, Maher JM, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010

    • Author(s)
      Motohashi H, Kimura M, Fujita R, Takayama M, Pan XQ, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M.
    • Journal Title

      Blood 115

      Pages: 677-686

    • NAID

      40019431698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance2010

    • Author(s)
      Kikuchi N, Ishii Y, Morishima Y, Yageta Y, Haraguchi N, Itoh K, Yamamoto M, Hizawa N., Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance
    • Journal Title

      Respir Res

      Volume: 11 Pages: 31-42

    • NAID

      120007138178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Novel regulation of the Nrf2-Keap1 pathway by the selective autophagy substrate p622010

    • Author(s)
      Komatsu M, Kurokawa H, Waqun S, Iaguchi K, Kobayashi A, Ichimura Y, Sou Y-S, Ueno I, Sakamoto A, Tong KI, Kim M, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] ストレスと生体反応. Nrf2-Keap1システムによるストレス応答制御2010

    • Author(s)
      宇留野晃、森口尚、山本雅之
    • Journal Title

      Diabetes Frontier

      Volume: 21 Pages: 412-417

    • Data Source
      KAKENHI-PROJECT-22890014
  • [Journal Article] NF-E2 domination over Nrf2 promotes ROS accumulation and megakaryocytic maturation2010

    • Author(s)
      Motohashi H, Kimura M, Fujita R, Takayama M, Pan XQ, Katsuoka F, Aburatani H, Bresnick EH, Yamamoto M
    • Journal Title

      Blood 115

      Pages: 677-686

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene.2010

    • Author(s)
      Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, Kleiner-Hancock HE.
    • Journal Title

      BMC Cancer

      Volume: 10 Pages: 540-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Keap 1 homodimer is a forked-stem structure with two large spheres en closing the intervening, double glycine repeat, and C-terminal domains2010

    • Author(s)
      Ogura T, Tong KI, Mio K, Maruyama Y, Kurokawa H, Sato C, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA 107

      Pages: 2842-2847

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene2010

    • Author(s)
      Becks L, Prince M, Burson H, Christophe C, Broadway M, Itoh K, Yamamoto M, Mathis M, Orchard E, Shi R, McLarty J, Pruitt K, Zhang S, Kleiner-Hancock HE
    • Journal Title

      BMC Cancer

      Volume: 10 Pages: 540-556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance.2010

    • Author(s)
      Kikuchi N, Ishii Y, Morishima Y, Yageta Y, Haraguchi N, Itch K, Yamamoto M, Hizawa N.
    • Journal Title

      Respir Res

      Volume: 11 Pages: 31-42

    • NAID

      120007138178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] The rise of antioxidant signaling-the evolution and hormetic actions of Nrf22010

    • Author(s)
      Maher J, Yamamoto M
    • Journal Title

      Antioxidant Redox Biol

      Volume: 244 Pages: 4-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytochrome P450 2A5 constitutive expression and induction by heavy metalsH, is dependent on redox-sensitive transcription factor Nrf2 in liver.2010

    • Author(s)
      lammsa v, levonen AL, Leinonen H Yla-Herttuala S, Yamamoto M, Hakkola J.
    • Journal Title

      Chem Res Toxicol

      Volume: 23 Pages: 977-985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response.2010

    • Author(s)
      Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G.
    • Journal Title

      Arterioscler Thromb Vase Biol

      Volume: 30 Pages: 1553-1556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Novel regulation of the Nrf2-Keap1 pathway by the selective autophagy substrate p622010

    • Author(s)
      M. Komatsu, H. Kurokawa, S. Waguri, K. Taguchi, A. Kobayashi, Y. Ichimura, Y-S. Sou, I. Ueno, A. Sakamoto, K.I. Tong, M. Kim, S. Iemura, T. Natsume, T. Ueno, E. Kominami, H. Motohashi, K. Tanaka, M. Yamamoto
    • Journal Title

      Nat. Cell Biol. 12

      Pages: 213-223

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Role of NrfZ and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells2010

    • Author(s)
      Kosaka K, Mimura J, Itoh K, Satoh T, Shimojo Y, Kitajima C, Maruyama A, Yamamoto M, Shirasawa T.
    • Journal Title

      J.Biochem. 147

      Pages: 73-81

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis2010

    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y. S., Ueno, I., Sakamoto, A., Tong, K. I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M.
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response2010

    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy.2010

    • Author(s)
      Uno K, Prow TW, Bhutto IA, Yerrapureddy A, McLeod DS, Yamamoto M, Reddy SP, Lutty GA.
    • Journal Title

      Exp Eye Res.

      Volume: 90 Pages: 493-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Ischemia-Induced Neovascularization by Enhancing the Inflammatory Response2010

    • Author(s)
      Ichihara S, Yamada Y, Liu F, Murohara T, Itoh K, Yamamoto M, Ichihara G
    • Journal Title

      Arterioscler Thromb Vasc Biol

      Volume: 30 Pages: 1553-1556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Increased susceptibility of Nrf2 null mice to 1-bromopropane-induced hepatotoxicity2010

    • Author(s)
      Liu F, Ichihara S, Valentine WM, Itoh K, Yamamoto M, Mohideen SS, Kitoh J, Ichihara G
    • Journal Title

      Toxicol Sci

      Volume: 115 Pages: 596-606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keapl.2010

    • Author(s)
      Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Select heterozygous Keapl mutations have a dominant-negative effect on wild-type Keapl in vivo.2010

    • Author(s)
      Suzuki T, Maher J, Yamamoto M.
    • Journal Title

      Cancer Res.

      Volume: 71 Pages: 1700-1709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Increased susceptibility of Nrf2 null mice to 1-bromopropane-induced hepatotoxicity.2010

    • Author(s)
      Liu F, Ichihara S, Valentine WM, Itch K, Yamamoto M, Mohideen SS, Kitoh J, Ichihara G.
    • Journal Title

      Toxicol Sci

      Volume: 115 Pages: 596-606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] ストレスと生体反応~Nrf2-Keaplシステムによるストレス応答制御~2010

    • Author(s)
      宇留丑晃、森口尚、山本雅之
    • Journal Title

      Diabetes Frontier

      Volume: 21 Pages: 412-417

    • Data Source
      KAKENHI-PROJECT-22890014
  • [Journal Article] Nrf2 is closely related to allergic airway inflammatory responses induced by low-dose diesel exhaust particles in mice2010

    • Author(s)
      Li YJ, Takizawa H, Azuma A, Kohyama T, Yamauchi Y, Takahashi S, Yamamoto M, Kawada T, Kudoh S, Sugawara I
    • Journal Title

      Clin Immunol

      Volume: 137 Pages: 234-241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The transcriptome of Nrf2^-/- Mice provides evidence for impaired cell cycle progression in the development of cigarette-smoke-induced emphysematous changes.2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T.
    • Journal Title

      Tox Sci

      Volume: 115 Pages: 238-252

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Novel type of E3 ligase for Ufm 1-conjugating system2010

    • Author(s)
      Tatsumi K, Sou Y-S, Tada N, Nakamura E, Iemura S-i, Natsume T, Kang SH, Chung C H, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M.
    • Journal Title

      J Biol Chem 285

      Pages: 5417-5427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Suppression of SLCIIA2 Expression is essential to maintain duodenal integrity during dietary iron overload.2010

    • Author(s)
      Shirase T, Mori K, Okazaki Y, Itoh K, Yamamoto M, Tabuchi M, Kishi F, Jiang L, Akatsuka S, Nakao K, Toyokuni S.
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 677-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Genetic analysis of cytoprotective functions supported by graded expression of Keap12010

    • Author(s)
      Taguchi K, Maher J, Suzuki T, Kawatani Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 3016-3026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu, M., Kurokawa, H., Waguri, S., Taguchi, K., Kobayashi, A., Ichimura, Y., Sou, Y.S., Ueno, I., Sakamoto, A., Tong, K.I., Kim, M., Nishito, Y., Iemura, S., Natsume, T., Ueno, T., Kominami, E., Motohashi, H., Tanaka, K., Yamamoto, M
    • Journal Title

      Nat Cell Biol. 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung.2010

    • Author(s)
      Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M.
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 1833-1843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] WFA-positive sialylated MUC1 is a high-sensitivity biliary marker for intrahepatic cholangiocarcinoma2010

    • Author(s)
      Matsuda, A., Kuno, A., Kawamoto, K., Matsuzaki, H., Irimura, T., Ikehara, Y., Zen, Y., Nakanuma, Y., Yamamoto, M., Ohkohchi, N., Shoda, J., Hirabayashi, J., Narimatsu, H
    • Journal Title

      Hepatology

      Volume: 52 Pages: 174-182

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Journal Article] The anemia of the newborn induces erythropoietin expression in the developing mouse retina2010

    • Author(s)
      Scheerer N, Dunker N, Imagawa S, Yamamoto M, Suzuki N, Fandrey J., The anemia of the newborn induces erythropoietin expression in the developing mouse retina
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010

    • Author(s)
      Sugimoto, H., Okada, K., Shoda, J., Warabi, E., Ishige, K., Ueda, T., Taguchi, K., Yanagawa, T., Nakahara, A., Hyodo, I., Ishii, T., Yamamoto, M
    • Journal Title

      Am J Physiol

      Volume: 298 Pages: 283-294

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Journal Article] Nrf2 is closely related to allergic airway inflammatory responses induced bylow-dose diesel exhaust particles in mice.2010

    • Author(s)
      Li YJ, Takizawa H, Azuma A, Kohyama T, Yamauchi Y, Takahashi S, Yamamoto M, Kawada T, Kudoh S, Sugawara I.
    • Journal Title

      Clin Immunol

      Volume: 137 Pages: 234-241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucurono syltransferases during BBN-induced urinary bladder carcinogenesis in mice2010

    • Author(s)
      Iida K, Itoh K, Mimura J, Ohyama C, Fujii-Kuriyama Y, Shimazui T, Akaza H, Yamamoto M
    • Journal Title

      J Biochem 147

      Pages: 353-360

    • NAID

      10027874393

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Novel regulation of the Nrf2-Keap1 pathway by the selective autophagy substrate p622010

    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou Y-S, Ueno I, Sakamoto A, Tong KI, Kim M, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M
    • Journal Title

      Nature Cell Biol 12

      Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Role of Nrf2 in retinal vascular development and the vaso-obliterative phase of oxygen-induced retinopathy2010

    • Author(s)
      Uno K, Prow TW, Bhutto IA, Yerrapureddy A, McLeod DS, Yamamoto M, Reddy SP, Lutty GA
    • Journal Title

      Exp Eye Res

      Volume: 90 Pages: 493-500

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic analysis of hierarchical regulation for Gata1 and NF-E2 p45 gene expression in megakaryopoiesis2010

    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol 12

      Pages: 3016-3026

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Suppression of SLC11A2 Expression is essential to maintain duodenal integrity during dietary iron overload2010

    • Author(s)
      Shirase T, Mori K, Okazaki Y, Itoh K, Yamamoto M, Tabuchi M, Kishi F, Jiang L, Akatsuka S, Nakao K, Toyokuni S
    • Journal Title

      Am J Pathol

      Volume: 177 Pages: 677-685

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver2010

    • Author(s)
      Lamsa V, Levonen AL, Leinonen H, Yla-Herttuala S, Yamamoto M, Hakkola J
    • Journal Title

      Chem Res Toxicol

      Volume: 23 Pages: 977-985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway.2010

    • Author(s)
      Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M, Hirohashi S.
    • Journal Title

      Cancer Res

      Volume: 70 Pages: 9095-9105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Nrf2-deficiency creates a responsive microenvironment for metastasis to the lung2010

    • Author(s)
      Satoh H, Moriguchi T, Taguchi K, Takai J, Maher JM, Suzuki T, Winnard PT Jr, Raman V, Ebina M, Nukiwa T, Yamamoto M
    • Journal Title

      Carcinogenesis

      Volume: 31 Pages: 1833-1843

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Global downstream pathway analysis reveals a dependence of oncogenic NF-E2-related factor 2 mutation on the mTOR growth signaling pathway2010

    • Author(s)
      Shibata T, Saito S, Kokubu A, Suzuki T, Yamamoto M, Hirohashi S
    • Journal Title

      Cancer Res

      Volume: 70 Pages: 9095-9105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The flavanol(-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway.2010

    • Author(s)
      Shah ZA, Li RC, Ahmad AS, Kensler TW, Yamamoto M, Biswal S, Dore S.
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 30 Pages: 1951-1961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defense and lipid metabolism as primary Nrf2-dependent pathways in the liver.2010

    • Author(s)
      Kitteringham NR, Abdullah A, Walsh J, Randle L, Jenkins RE, Sison R, Goldring CE, Sanderson C, Williams S, Higgins L, Yamamoto M, Hayes J, Park BK.
    • Journal Title

      J Proteomics

      Volume: 73 Pages: 1612-1631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defense and lipid metabolism as primary Nrf2-dependent pathways in the liver2010

    • Author(s)
      Kitteringham NR, Abdullah A, Walsh J, Randle L, Jenkins RE, Sison R, Goldring CE, Sanderson C, Williams S, Higgins L, Yamamoto M, Hayes J, Park BK
    • Journal Title

      J Proteomics

      Volume: 73 Pages: 1612-1631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The anemia of the newborn induces erythropoietin expression in the developing mouse retina.2010

    • Author(s)
      Scheerer N, Dunker N, Imagawa S, Yamamoto M, Suzuki N, Fandrey J.The anemia of the newborn induces erythropoietin expression in the developing mouse retina.
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol

      Volume: 299

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Loss of the Gata1 gene IE exon leads to variant transcript expression and the production of a GATA1 protein lacking the N-terminal domain2010

    • Author(s)
      Kobayashi E, Shimizu R, Kikuchi Y, Takahashi S, Yamamoto M
    • Journal Title

      J Biol Chem 285

      Pages: 773-783

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Keap1 homodimer is a forked-stem structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains2010

    • Author(s)
      Ogura T, Tong KI, Mio K, Maruyama Y, Kurokawa H, Sato C, Yamamoto M.
    • Journal Title

      Proc Natl Acad Sci USA 285

      Pages: 5417-5427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells2010

    • Author(s)
      Gruber F, Mayer H, Lengauer B, Mlitz V, Sanders JM, Kadl A, Bilban M, de Martin R, Wagner O, Kensler TW, Yamamoto M, Leitinger N, Tschachler E.
    • Journal Title

      FASEB J 24

      Pages: 39-48

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Keap1 homodimer is a forked-stem structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains2010

    • Author(s)
      Ogura T, Tong KI, Mio K, Maruyama Y, Kurokawa H, Sato C, Yamamoto M
    • Journal Title

      Proc Natl Acad Sci USA 107

      Pages: 2842-2847

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Regulation of Notch1 signaling by Nrf2 : Implications for tissue regeneration2010

    • Author(s)
      Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak M-K, Misra V, Biswal S, Yamamoto M, Kensler TW
    • Journal Title

      Science Signaling

      Volume: 3 Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Efficient transient rescue of hematopoietic mutant phenotypes in zebrafish using To12-mediated transgenesis2010

    • Author(s)
      Takeuchi M, Kaneko H, Nishikawa K, Kawakami K, Yamamoto M, Kobayashi M.
    • Journal Title

      Dev Growth Differ (未定, 印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Irreversible down-regulation of UDP-glucuronosyltransferases through AhR inactivation during urinary bladder carcinogenesis2010

    • Author(s)
      Iida K, Itoh K, Mimura J, Ohyama C, Fujii-Kuriyama Y, Shimazui T, Akaza H, Yamamoto M.
    • Journal Title

      J.Biochem. 147

      Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The rise of antioxidant signaling-the evolution and hormetic actions of Nrf2.2010

    • Author(s)
      Maher J, Yamamoto M.
    • Journal Title

      Antioxidant Redox Biol

      Volume: 244 Pages: 4-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Keap1 homodimer is a forked-stem structure with two large spheres enclosing the intervening, double glycine repeat, and C-terminal domains2010

    • Author(s)
      Ogura T, Tong KI, Mio K, Maruyama Y, Kurokawa H, Sato C, and Yamamoto M
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 285 Pages: 5417-5427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2010

    • Author(s)
      Suzuki T, Maher J, Yamamoto M
    • Journal Title

      Cancer Res

      Volume: 71 Pages: 1700-1709

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Regulation of Notchl signaling by Nrf2 : Implications for tissue regeneration.2010

    • Author(s)
      Wakabayashi N, Shin S, Slocum SL, Agoston ES, Wakabayashi J, Kwak M-K, Misra V, Biswal S, Yamamoto M, Kensler TW.
    • Journal Title

      Science Signaling

      Volume: 3 Pages: 1-11

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] Genetic analysis of hierarchical regulation for Gatal and NF-E2 p45 gene expression in megakaryopoiesis.2010

    • Author(s)
      Takayama M, Fujita R, Suzuki M, Okuyama R, Aiba S, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol

      Volume: 30 Pages: 2668-2680

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] The critical role of nitric oxide signaling, via protein S-guanylation and nitratedcyclic GMP,in the antioxidant adaptive response.2010

    • Author(s)
      Fujii S, Sawa T, Ihara H, Tong KI, Ida T, Okamoto T, Ahtesham AK, Ishima Y, Motohashi H, Yamamoto M, Akaike T.
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 23970-23984

    • Data Source
      KAKENHI-PROJECT-22659056
  • [Journal Article] The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap12010

    • Author(s)
      Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, and Yamamoto M
    • Journal Title

      Nature Cell Biol

      Volume: 12 Pages: 213-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The transcriptome of Nrf2^<-/-> Mice provides evidence for impaired cell cycle progress ion in the development of cigarette-smoke-induced emphysematous changes2010

    • Author(s)
      Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Schuller J, Xu H, Taguchi K, Yamamoto M, Muller T
    • Journal Title

      Tox Sci (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] The flavanol (-)-epicatechin prevents stroke damage through the Nrf2/HO1 pathway2010

    • Author(s)
      Shah ZA, Li RC, Ahmad AS, Kensler TW, Yamamoto M, Biswal S, Dore S
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 30 Pages: 1951-1961

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease2009

    • Author(s)
      Rojo AI, Innamorato NG, Martin-Moreno AM, De Ceballos ML, Yamamoto M, Cuadrado A
    • Journal Title

      Glia 58

      Pages: 588-598

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment2009

    • Author(s)
      Abe, K., Shimizu, R., Pan, X., Hamada, H., Yoshikawa, H., Yamamoto, M.
    • Journal Title

      Exp. Hematol. 37

      Pages: 435-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19208027
  • [Journal Article] Constitutively active aryl hydrocarbon receptor expressed in T cells increases immunization-induced IFN-γ production in mice but does not suppress Th2-cytokine production or antibody production2009

    • Author(s)
      Nohara K, Suzuki T, Ao K, Murai H, Miyamoto Y, Inouye K, Pan X, Motohashi H, Fujii-Kuriyama Y, Yamamoto M, Tohyama C.
    • Journal Title

      Int.Immunol 21

      Pages: 769-777

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Differential contribution of the Gata1 gene hematopoietic enhancer to erythroid differentiation2009

    • Author(s)
      Suzuki M, Moriguchi T, Ohneda K, Yamamoto M
    • Journal Title

      Mol Cell Biol 29

      Pages: 1163-1175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment2009

    • Author(s)
      Abe K, Shimizu R, Pan X, Hamada H, Yoshikawa H, and Yamamoto M
    • Journal Title

      Exp Hematol 37

      Pages: 435-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Targeting Nrf2 with the Triterpenoid CDDO-Imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice2009

    • Author(s)
      Sussan IE, Hangasamy T, Blake DJ, Mainotra U, El-Haddad H, Bedja D, Yates MS, Kombairaju P, Yamamoto M, Liby KT, Sporn MB, Gabrielson KL, Champion HC, Tuder RM, Kensler TW, Biswal S
    • Journal Title

      Proc Natl Acad Sci USA 106

      Pages: 250-255

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article]2009

    • Author(s)
      井上大輔、本橋ほづみ、山本雅之
    • Journal Title

      酸化ストレスと呼吸器疾患(先端医学社)

      Pages: 6-7

    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009

    • Author(s)
      Okada, K., Shoda, J., Taguchi, K., Maher, J. M., Ishizaki, K., Inoue, Y., Ohtsuki, M., Goto, N., Sugimoto, H., Utsunomiya, H., Oda, K., Warabi, E., Ishii, T., Yamamoto, M
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 389 Pages: 431-436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009

    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T
    • Journal Title

      Mol Cell Biol 29

      Pages: 6232-6244

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] 1-Cyano-2, 3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic{alpha}, {beta}-unsaturated aldehyde acrolein2009

    • Author(s)
      Kelleher MO, McMahon M, Eggleston IM, Dixon MJ, Taguchi K, Yamamoto M, Hayes JD.
    • Journal Title

      Carcinogenesis 30

      Pages: 1754-1762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Stem cells of GATA1-related leukemia undergo pernicious changes after 5-fluorouracil treatment2009

    • Author(s)
      Abe K, Shimizu R, Pan X, Hamada H, Yoshikawa H, Yamamoto M
    • Journal Title

      Exp Hematol 37

      Pages: 435-445

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009

    • Author(s)
      Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M
    • Journal Title

      Biochem Biophys Res Commun 389

      Pages: 431-436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans2009

    • Author(s)
      Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, Tauchi M, Suzuki H, Hyodo I, Yamamoto M
    • Journal Title

      Cancer Prev Res 2

      Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents2009

    • Author(s)
      Higgins LG, Kelleher MO, Eggleston IM, Itoh K, Yamamoto M, Hayes JD
    • Journal Title

      Toxicol Appl Pharmacol 237

      Pages: 267-280

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of Nrf2 and oxidation of Keap 12009

    • Author(s)
      Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Hirofumi M, Yoshikawa T.
    • Journal Title

      J.Pharmacol.Exp.Ther. 331

      Pages: 255-264

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems2009

    • Author(s)
      Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Sugimoto H, Utsunomiya H, Oda K, Warabi E, Ishii T, Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun 389

      Pages: 431-436

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Transcription factor Nrf2 is protective during ischemic and nephrotoxic acute kidney injury in mice2009

    • Author(s)
      Liu M, Grigoryev DN, Crow MT, Haas M, Yamamoto M, Reddy SP, Rabb H.
    • Journal Title

      Kidney International 76

      Pages: 277-285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The triterpenoid CDDO-Imidazolide confers potent protection against hyperoxic acute lung injury in mice2009

    • Author(s)
      Reddy NM, Suryanaraya V, Yates MS, Kleeberger SR, Hassoun PM, Yamamoto M, Liby KT, Sporn MB, Kensler TW, Reddy SP
    • Journal Title

      Am J Respir Crit Care Med 180

      Pages: 867-874

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Direct binding of pRb/E2F-2 to GATA-1 regulates maturation and terminal cell division during erythropoiesis2009

    • Author(s)
      Kadri Z, Shimizu R, Ohneda O, Maouche-Chretien L, Gisselbrecht S, Yamamoto M, Romeo PH, Leboulch P, Chretien S
    • Journal Title

      PLoS Biol 7

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 enhances cell proliferation and resistance to anticancer drugs in hum an lung cancer2009

    • Author(s)
      Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N, Itoh K, Yamamoto M
    • Journal Title

      Clin Cancer Res 15

      Pages: 3423-3432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs2009

    • Author(s)
      Singh A, Ling G, Suhasini AN, Z hang P, Yamamoto M, Navas-Acien A, Cosgrove G, Tuder RM, Kensler TW, Watson WH, Biswal S
    • Journal Title

      Free Radic Biol Med 46

      Pages: 376-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Leukemia-related transcription factor TEL/ETV6 expands erythroid precursors and stimulates hemoglobin synthesis.2009

    • Author(s)
      Eguchi-lshimae M, Eguchi M, Maki K, Porcher C, Shimizu R, Yamamoto M, and Mitani K
    • Journal Title

      Cancer Sci 100

      Pages: 689-697

    • NAID

      10025144516

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice2009

    • Author(s)
      Reddy NM, Kleeberger SR, Kensler TW, Yamamoto M, Hassoun PM, Reddy SP.
    • Journal Title

      Journal of Immunology 18

      Pages: 7264-7271

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Increased Nrf2 activation in Keap1-knockdown mice increases hepatic cytoprotective genes that detoxify electrophiles but not reactive oxygen species2009

    • Author(s)
      Reisman SA, Yeager RL, Yamamoto M, Klaassen CD
    • Journal Title

      Tox Sci 108

      Pages: 35-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Dietary sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori-infected mice and humans2009

    • Author(s)
      Yanaka A, Fahey JW, Fukumoto A, Nakayama M, Inoue S, Zhang S, Tauchi M, Suzuki H, Hyodo I, Yamamoto M.
    • Journal Title

      Cancer Prev.Res. 2

      Pages: 353-360

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds2009

    • Author(s)
      Kobayashi M, Li L, Iwamoto N, Nakajima-Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M
    • Journal Title

      Mol Cell Biol 29

      Pages: 493-502

    • NAID

      120007138388

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Structural basis of alternative DNA recognition by Maf transcription factors2009

    • Author(s)
      Kurokawa H, Motohashi H, Sueno S, Kimura M, Takagawa H, Kanno Y, Yamamoto M, Tanaka T.
    • Journal Title

      Mol.Cell.Biol. 29

      Pages: 6232-6244

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds2009

    • Author(s)
      Kobayashi M, Li L, Iwamoto N, Nakajima- Takagi Y, Kaneko H, Nakayama Y, Eguchi M, Wada Y, Kumagai Y, Yamamoto M
    • Journal Title

      Mol Cell Biol 29

      Pages: 493-502

    • NAID

      120007138388

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide2009

    • Author(s)
      Shin S, Wakabayashi J, Yates MS, Wakabayashi N, Dolan PM, Aja S, Liby KT, Sporn MB, Yamamoto M, Kensler TW
    • Journal Title

      Eur J Pharmacol 620

      Pages: 138-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] nnate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice2009

    • Author(s)
      Reddy NM, Suryanarayana V, Kalvakolanu DV, Yamamoto M, Kensler TW, Hassoun PM, Kleeberger SR, Reddy SP.
    • Journal Title

      J.Immunology 183

      Pages: 4601-4608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic versus chemoprotective activation of Nrf2 signaling : overlapping yet distinct gene expression profiles between Keap 1 knockout and trite rpenoid treated mice2009

    • Author(s)
      Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW.
    • Journal Title

      Carcinogenesis 30

      Pages: 1024-1031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 1-Cyano-2, 3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic{alpha},{beta}-unsaturated aldehyde acrolein2009

    • Author(s)
      Kelleher MO, McMahon M, Eggleston IM, Dixon MJ, Taguchi K, Yamamoto M, Hayes JD
    • Journal Title

      Carcinogenesis 30

      Pages: 1754-1762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant2009

    • Author(s)
      Shimizu R, Kobayashi E, Engel JD, Yamamoto M
    • Journal Title

      Genes Cells 14

      Pages: 1119-1131

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 protects against maladaptive cardiac responses to hemodynamic stress2009

    • Author(s)
      Li J, Ichikawa T, Villacorta L, Janicki JS, Brower GL, Yamamoto M, Cui T.
    • Journal Title

      Arterioscler Thromb.Vasc.Biol. 29

      Pages: 1843-1850

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice2009

    • Author(s)
      Prince M, Li Y, Childers A, Itoh K, Yamamoto M, Kleiner HE
    • Journal Title

      Toxicol Lett 185

      Pages: 180-186

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Genetic versus chemoprotective activation of Nrf2 signaling : overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid treated mice2009

    • Author(s)
      Yates MS, Tran QT, Dolan PM, Osburn WO, Shin S, McCulloch CC, Silkworth JB, Taguchi K, Yamamoto M, Williams CR, Liby KT, Sporn MB, Sutter TR, Kensler TW
    • Journal Title

      Carcinogenesis 30

      Pages: 1024-1031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Increased Nrf2 activation in Keapl-knockdown mice increases hepatic cyto protective genes that detoxify electrophiles but not reactive oxygen species2009

    • Author(s)
      Reisman SA, Yeager RL, Yamamoto M, and Klaassen CD
    • Journal Title

      Tox Sci 108

      Pages: 35-47

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer2009

    • Author(s)
      Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N, Kikuchi N, Satoh H, Sakamoto T, Hizawa N, Itoh K, Yamamoto M.
    • Journal Title

      Clin.Cancer Res. 15

      Pages: 3423-3432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008

    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M.
    • Journal Title

      Mol Cell Biol 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] GATA-1の機能異常と白血病-Leukemogenesis related to GATA-1 mutation-2008

    • Author(s)
      安倍加奈子、清水律子、山本雅之
    • Journal Title

      日本産婦人科血液学会誌 17

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] GATA1-related leukemias.2008

    • Author(s)
      R. Shimizu, M. Yamamoto, et. al. (total 3, last)
    • Journal Title

      Nat. Rev. Cancer 8

      Pages: 279-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] NRF1 and NRF2 play distinct roles in activation of antioxidant response element-dependent genes2008

    • Author(s)
      Ohtsuji M, Katsuoka F, Kobayashi A, Aburatani H, Hayes JD, Yamamoto M
    • Journal Title

      J Biol Chem 283

      Pages: 33554-33562

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Genetic or pharmacologic amplification of Nrf2 signaling inhibits acute intiammatory liver injury in mice2008

    • Author(s)
      Osburn WO, Yates MS, Dolan PD Liby KT, Sporn MB, Taguchi K, Yamamoto M, and Kensler T
    • Journal Title

      Toxicol Sci 104

      Pages: 218-227

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in deter mining Nrf2 activity2008

    • Author(s)
      Yamamoto T, Suzuki T, 他
    • Journal Title

      Molecular and Cellular Biology 28

      Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] GATA1-related leukaemias2008

    • Author(s)
      R. Shimizu, J.D. Engel, M. Yamamoto
    • Journal Title

      Nat. Rev. Cancer 8

      Pages: 279-287

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap 12008

    • Author(s)
      Padmanabhan B, Tong KI, Kobay ashi A, Yamamoto M, and Yokoyama S
    • Journal Title

      J Synchrotron Radiat 15(Pt3)

      Pages: 273-276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development2008

    • Author(s)
      Marhenke S, Lamle J, Buitrago-M olina LE, Cali& JM, Geffers R, Finegold M, Sporn M, Yamamoto M, Manns MP, Grompe M, and Vogel A
    • Journal Title

      Hepatology 48

      Pages: 487-496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Molecular evolution of Keap1: Two Keap1 molecules with distinctive IVR structures are conserved among fish2008

    • Author(s)
      Li L, Kobayashi M, Kaneko H, Nakajima-Takagi Y, Nakayama Y, Yamamoto M
    • Journal Title

      J Biol Chem 283

      Pages: 3248-3255

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 mediates cancer protection but not prolongevity induced by caloric restriction2008

    • Author(s)
      Pearson KJ, Lewis KN, Price NL, Chang JW, Perez E, Cascajo M V, Tamashiro KL, Poosala S, Csiszar A, Ungvari Z, Kensler TW, Yamamoto M, Egan JM, Longo DL, Ingram DK, Navas P, de Cabo R
    • Journal Title

      Proc Nati Acad Sci USA 105

      Pages: 2325-2330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Disruption of the transcription factor Nrf2 promotes pro-oxidative dendritic cells that stimulate Th2-like immunoresponsiveness upon activation by ambient particulate matter2008

    • Author(s)
      Williams MA, Rangasamy T, Bauer SM, Killedar S, Karp M, Kensler TW, Yamamoto M, Breysse P, Biswal S, and Georas SN
    • Journal Title

      J Immunol 181

      Pages: 4545-4159

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008

    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 28 Pages: 2758-2770

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy2008

    • Author(s)
      Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, Asamura H, Yamamoto M, and Hirohashi S
    • Journal Title

      Proc Natl Acad Sci USA 105

      Pages: 13568-13573

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A possible role of Nrf2 in prevention of renal oxidative damage by ferric nitrilotriacetate2008

    • Author(s)
      Kanki K, Umemura T, Kitamura Y , Ishii Y, Kuroiwa Y, Kodama Y, Itoh K, Yamamoto M, Nishikawa A. and Hirose M
    • Journal Title

      Toxicol Pathol 36

      Pages: 353-361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice2008

    • Author(s)
      Yoh K, Hirayama A, Ishizaki K, Y amada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, and Yamamoto M
    • Journal Title

      Genes Cells 13

      Pages: 1159-1170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Ablation of Gata1 in adult mice results in aplastic crisis, revealing its essential role in steady state and stress erythropoiesis2008

    • Author(s)
      Gutierrez L, Tsukamoto S, Suzuki M, Yamamoto-Mukai H, Yamamoto M, Philipsen S, and Ohneda K
    • Journal Title

      Blood 111

      Pages: 4375-4385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] The transcription factor Nrf2 is a therapeutic target against brain intlammation2008

    • Author(s)
      Innamorato NG, Rojo Al, Garcia-Yagile kJ, Yamamoto M, de Ceballos ML. and Cuadrado A
    • Journal Title

      J Immunol 181

      Pages: 680-689

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] NRF1 and NRF2 play distinct roles in activation of antioxidant response element-dependent genes2008

    • Author(s)
      Ohtsuji M, Katsuoka F, Kobayashi A, Aburatani H, Hayes JD, and Yamamoto M
    • Journal Title

      J Biol Chem

      Volume: 283 Pages: 33554-33562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells2008

    • Author(s)
      Taguchi K, Shimada M, Fujii S, Sumi D, Pan X, Yamano S, Nishiy ama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, and Kumagai Y
    • Journal Title

      Free Radic Biol Med 44

      Pages: 1645-1655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] NRF1 and NRF2 play distinct roles in activation of antioxidant response element-dependent genes2008

    • Author(s)
      Ohtsuji M, Katsuoka F, Kobayashi A, Aburatani H, Hayes JD, Yamamoto M.
    • Journal Title

      J Biol Chem 283

      Pages: 33554-33562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein2008

    • Author(s)
      Higgins LG, Cavin C, Itoh K, Yamamoto M, and Hayes JD
    • Journal Title

      Toxicol Appl Pharmacol 226

      Pages: 328-337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA-1の機能異常と白血病-Leukemogenesis related to GATA-1 mutation-2008

    • Author(s)
      安倍加奈子、清水律子、山本雅之
    • Journal Title

      日本産婦人科血液学会誌 17

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Loss of Keap 1 function activates Nrf2 and provides advantages for lung cancer cells growth2008

    • Author(s)
      Ohta T, Iijima K, Miyamoto M, Nakahara I, Odagawa R, Mimaki S, Sakiyama T, Tanaka H, Ohtsuji M, Suzuki T, Kobayashi A, Shibata T, Yamamoto M, and Hirohashi S
    • Journal Title

      Cancer Res 68

      Pages: 1303-1309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice2008

    • Author(s)
      Yoh K, Hirayama A, Ishizaki K, Yamada A, Takeuchi M, Yamagishi S, Morito N, Nakano T, Ojima M, Shimohata H, Itoh K, Takahashi S, Yamamoto M
    • Journal Title

      Genes Cells 13

      Pages: 1159-1170

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity2008

    • Author(s)
      Yamamoto T, Suzuki T, Kobayashi A, Wakabayashi J, Maher J, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol 28

      Pages: 2758-2770

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Attenuation of UVB-induced sunburn reaction and oxidative DNA damage with no alterations in UVB-induced skin carcinogenesis in Nrf2 gene-deficient mice2008

    • Author(s)
      Kawachi Y, Xu X, Taguchi S, Sakurai H, Nakamura Y, Ishii Y, Fujisawa Y, Furuta J, Takahashi T, Itoh K, Yamamoto M, Yamazaki F, and Otsuka F
    • Journal Title

      J Invest Dermatol 128

      Pages: 1773-1779

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Disruption of Nrf2 enhances susceptibility to airway inflammatory responses induced by low-dose diesel exhaust particles in mice2008

    • Author(s)
      Li YJ, Takizawa H, Azuma A, Kohyama T, Yamauchi Y, Takahashi S, Yamamoto M, Kawada T, Kudoh S. and Suaawara I
    • Journal Title

      Clin Immunol 128

      Pages: 366-373

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9;9)-derived fusion gene product, SET/TAF-Ib-CAN/Nup 214.2008

    • Author(s)
      Saito S, Nouno K, Slumizu R, Yamamoto M, and Nagata K.
    • Journal Title

      J Cell Physiol. 214

      Pages: 322-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] GATA-1の機能異常と白血病-Leukemogenesis related to GATA-1 mutation-2008

    • Author(s)
      安倍加奈子・清水律子・山本雅之
    • Journal Title

      日本産婦人科血液学会誌 17

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2-Keap1制御系から望む呼吸器疾患2008

    • Author(s)
      佐藤大希・山本雅之
    • Journal Title

      呼吸 27

      Pages: 439-445

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA-1の機能異常と白血病-Leukemogenesis related to GATA-1 mutation-2008

    • Author(s)
      安倍加奈子、清水律子、山本雅之
    • Journal Title

      日本産婦人科血液学会誌 17

      Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nuclear Factor E2-Related Factor 2-dependent myocardiac cytoprotection against oxidative and electrophilic stress2008

    • Author(s)
      Zhu H, Jia Z, Misra BR, Zhang L , Cao Z, Yamamoto M, Trush M A, Misra HP, and Li Y
    • Journal Title

      Cardiovasc Toxicol 8

      Pages: 71-85

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts2008

    • Author(s)
      Harada H, Sugimoto R, Watanabe A, Taketani S, Okada K, Warabi E, Siow R, Itoh K, Yamamoto M, and Ishii T
    • Journal Title

      Free Radical liesearcn 42

      Pages: 297-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA1-related leukaemias2008

    • Author(s)
      Shimizu R, Engel JD, Yamamoto, M.
    • Journal Title

      Nature Reviews Cancer 8

      Pages: 279-287

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Impairment of erythroid and megakaryocytic differentiation by a leukemia -associated and t(9; 9)-derived fusion gene product, SET/TAF-Ib-CAN/Nup 214.2008

    • Author(s)
      Saito S, Nouno K, Shimizu R, Yamamoto M, and Nagata K.
    • Journal Title

      J Cell Physiol. 214

      Pages: 322-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Deletion of the selenocysteine tRNA gene in macrophage and liver results in compensatory gene induction of cytoprotective enzymes by Nrf22008

    • Author(s)
      Suzuki T, Kelly VP, Motohashi H, Nakajima O, Takahashi S, Nishimura S, Yamamoto M
    • Journal Title

      J Biol Chem 283

      Pages: 2021-2030

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t(9 ; 9)-derived fusion gene product, SET/TAF-IB-CAN/Nup2142008

    • Author(s)
      Saito S, Nouno K, Shimizu R, Yamamoto M, and Nagata K
    • Journal Title

      J Cell Physiol 214

      Pages: 322-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development2008

    • Author(s)
      Marhenke S, Lamle J, Buitrago-Molina LE, Canon JM, Geffers R, Finegold M, Sporn M, Yamamoto M, Manns MP, Grompe M, and Vogel A
    • Journal Title

      Hepatology 48

      Pages: 487-496

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Impairment of erythroid and megakaryocytic differentiation by a leukemia-associated and t (9;9) -derived fusion gene product, SET/TAF-Ib-CAN/Nup214.2008

    • Author(s)
      Saito S, Nouno K, Shimizu R, Yamamoto M, and Nagata K.
    • Journal Title

      J Cell Physiol. 214

      Pages: 322-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy2008

    • Author(s)
      Shibata T, Ohta T, Tong KI, Kokubu A, Odogawa R, Tsuta K, Asamura H, Yamamoto M, Hirohashi S
    • Journal Title

      Proc Natl Acad Sci USA 105

      Pages: 13568-13573

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Repression via the GATA box is essential for tissue-specific erythropoietin gene expression2008

    • Author(s)
      Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, and Yamamoto M
    • Journal Title

      Blood

      Volume: 111 Pages: 5223-5362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer2008

    • Author(s)
      Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M, and Hirohashi S
    • Journal Title

      Gastroenterology 135

      Pages: 1358-1368

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA box is essential for tissue-specific erythropoietin gene expression2008

    • Author(s)
      Obara N, Suzuki N, Kim K, Nagasawa T, Imagawa S, Yamamoto M. Repression via the
    • Journal Title

      Blood 111

      Pages: 5223-5362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Ephrin-A1 promotes the malignant progression of intestinal tumors in Apc-mice2008

    • Author(s)
      Shi L, Itoh F, Itoh S, Takahashi S, Yamamoto M, and Kato M
    • Journal Title

      Oncogene 27

      Pages: 3265-3273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA1-related leukaemias2008

    • Author(s)
      Shimizu R, Engel JD and Yamamoto, M
    • Journal Title

      Nature Reviews Cancer 8

      Pages: 279-287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Oxidative and electrophilic stress induces Mrp transporters via the Nrf2 transcriptional pathway.2007

    • Author(s)
      Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, and Klaassen CD.
    • Journal Title

      Hepatology. 46

      Pages: 1597-1610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Different Electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, and Yamamoto M.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7511-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Dysfunction of Nrf2 decreases KBrO_3-induced oxidative DNA damage in Oggl-null mice.2007

    • Author(s)
      Jaloszynski P, Murata S, Shinkai Y, Takahashi S, Kumagai Y, Nishimura S, and Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 966-971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.2007

    • Author(s)
      Wang J, Fields J, Zhao C, Langer J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Free Rad Biol Med. 43

      Pages: 408-414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.2007

    • Author(s)
      Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Neuroscience. 147

      Pages: 53-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007

    • Author(s)
      Motohashi H, and Yamamoto M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Functional polymorphisms in the transcription factor NRF2 increase the risk of acute lung injury.2007

    • Author(s)
      Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho, H-Y, and Kleeberger SR.
    • Journal Title

      FASEB J. 21

      Pages: 2237-2246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] NRF2 modulates aryl hydrocarbon receptor signaling: Influence on adipogenesis.2007

    • Author(s)
      Shin S, Wakabayashi N, Misra V, Biswal S, Lee GH, Agoston ES, Yamamoto M, and Kensler TW.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7188-7197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cell cycle-dependent oscillation of GATA2 expression in hematopoietic cells.2007

    • Author(s)
      Koga S, Yamaguchi N, Abe T, Minegishi M, Tsuchiya S, Yamamoto M, and Minegishi N.
    • Journal Title

      Blood. 109

      Pages: 4200-4208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo [4, 5-f] quinoline.2007

    • Author(s)
      Kitamura Y, Umemura T, kanki K, Kodama Y, Kitamoto S, Saito K, Itoh K, Yamamoto M, Masegi T, Nishikawa A, and Hirose M.
    • Journal Title

      Cancer Sci. 98

      Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.2007

    • Author(s)
      Osburn WO, Karim B, Dolan PM, Liu G, Yamamoto M, Huso DL, and Kensler TW.
    • Journal Title

      Int J Cancer. 121

      Pages: 1883-1891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-lc expression.2007

    • Author(s)
      Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y, Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga JI, and Shimano H.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 329-335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Molecular mechanism of transcriptional repression of AhR repressor involving ANKRA2, HDAC4, and HDAC5.2007

    • Author(s)
      Oshima M, Mimura J, Yamamoto M, and Fujii-Kuriyama Y.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 276-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Loss of p62/SQSTM1 suppresses cytoplasmic inclusion body formation and liver injury in autophagy-deficient mouse. K2007

    • Author(s)
      Komatsu M, Waguri S, Koike M, Sou Y, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E and Tanaka k
    • Journal Title

      Cell. 131

      Pages: 1149-1163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Characterization of GATA-1^+ hemangioblastic cells in the mouse embryo.2007

    • Author(s)
      Yokomizo T, Takahashi S, Mochizuki N, Kuroha T, Ema M, Wakamatsu A, Shimizu R, Ohneda O, Osato. M, Okada H, Komori T, Ogawa M, Nishikawa S, Ito Y, and Yamamoto M.
    • Journal Title

      EMBO J. 26

      Pages: 184-196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t (8;21) (q24;q22) acute myeloid leukemia.2007

    • Author(s)
      Asou N, Yanagida M, Huang L, Yamamoto M, Shigesada K, Mitsuya H, Ito Y, and Osato M.
    • Journal Title

      Blood. 109

      Pages: 4023-4027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] 酸素センシングと赤血球造血シグナル2007

    • Author(s)
      今川重彦、小原 直、鈴木教郎、山本雅之
    • Journal Title

      細胞 39

      Pages: 537-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.2007

    • Author(s)
      Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Neuroscience. 147

      Pages: 53-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Potential involvement of pathophysiologically formed 8-nitroguanosine 3',5'-cyclic monophosphate in nitric oxide-induced signal transduction.2007

    • Author(s)
      Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, and Akaike T.
    • Journal Title

      Nature Chem Biol. 3

      Pages: 727-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.2007

    • Author(s)
      Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, and Kumagai Y.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 645-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts or gan protection against ischemia.2007

    • Author(s)
      Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M, van Ypersele de Strihou C, Hirayama N, and Miyata T.
    • Journal Title

      Arterioscler Thromb Vas Biol. 27

      Pages: 2548-2554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.2007

    • Author(s)
      Shah ZA, Li RC, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Neuroscience. 147

      Pages: 53-59

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Enhanced spontaneous and benzo[α]pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.2007

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T and Yamamoto M.
    • Journal Title

      Cancer Res. 67

      Pages: 5643-5648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements2007

    • Author(s)
      Motohashi H, Yamamoto M
    • Journal Title

      Cancer Sci 98

      Pages: 135-139

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Different Electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, and Yamamoto M.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7511-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Inchinkoto, an herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in rat livers.2007

    • Author(s)
      Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y and Suzuki H.
    • Journal Title

      Am J Physiol Gastrointestinal Liver Physiol. 295

      Pages: 1450-1463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Regulation of adipocyte differentiation of bone marrow stromal cells by transcription factor GATA-2.2007

    • Author(s)
      Okitsu Y, Takahashi S, Minegishi N, Kameoka J, Kaku M, Yamamoto M, Sasaki T, and Harigae H
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 383-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Molecular mechanism of transcriptional repression of AhR repressor in volving ANKRA2, HDAC4, and HDAC5.2007

    • Author(s)
      Oshima M, Mimura J, Yamamoto M, and Fujii-Kuriyama Y.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 276-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, and Yamamoto M
    • Journal Title

      Mol Cell Biol

      Volume: 27 Pages: 7511-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.2007

    • Author(s)
      Wang J, Fields J, Zhao C, Larger J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Free Rad Biol Med. 43

      Pages: 408-414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007

    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
    • Journal Title

      Biochem J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Use of gene manipulated mice in the study of erythropoietin gene expression.2007

    • Author(s)
      Suzuki N, Obara N, and Yamamoto M.
    • Journal Title

      Methods Enzymol. 435

      Pages: 157-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.2007

    • Author(s)
      Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, and Kumagai Y.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 645-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-lc expression.2007

    • Author(s)
      Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y. Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga JI. and Shimano H.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 329-335

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Potential involvement of pathophysiologically formed 8-nitroguanosine 3',5'-cyclic monophosphate in nitric oxide-induced signal transduction.2007

    • Author(s)
      Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, and Akaike T.
    • Journal Title

      Nature Chem Biol. 3

      Pages: 727-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.2007

    • Author(s)
      Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, and Kensler TW.
    • Journal Title

      Mol Cancer Therapeutics. 6

      Pages: 154-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Dynamic regulation of Gata factor levels is more important than their identity.2007

    • Author(s)
      Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindem M, Ohneda K, Grosveld F, Yamamoto M, and Philipsen S.
    • Journal Title

      Blood. 109

      Pages: 5481-5490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.2007

    • Author(s)
      Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim K-C, and Engel JD.
    • Journal Title

      Development. 139

      Pages: 1703-1712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Functional polymorphisms in the transcription factor NRF2 increase the risk of acute lung injury.2007

    • Author(s)
      Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho, H-Y, and Kleeberger SR.
    • Journal Title

      FASEB J. 21

      Pages: 2237-2246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t (8;21)(q24;q22) acute myeloid leukemia.2007

    • Author(s)
      Asou N, Yanagida M, Huang L, Yamamoto M, Shigesada K, Mitsuya H, Ito Y, and Osato M.
    • Journal Title

      Blood. 109

      Pages: 4023-4027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.2007

    • Author(s)
      Iida K, Itoh K, Maher JM, Kumagai Y, Oyasu R, Mori Y, Fukushima S, Shimazui T, Akaza H, and Yamamoto M.
    • Journal Title

      Carcinogenesis. 28

      Pages: 2398-2403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 酸化ストレス防御のための生体内センサー: Keap1-Nrf2制御システム2007

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      化学と生物 45

      Pages: 857-862

    • NAID

      10019973647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Molecular mechanism of transcriptional repression of AhR repressor in volving ANKRA2, HDAC4, and HDAC5.2007

    • Author(s)
      Oshima M, Mimura J, Yamamoto M, and Fujii-Kuriyama Y.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 276-282

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Regulation of adipocyte differentiation of bone marrow stromal cells by transcription factor GATA-2.2007

    • Author(s)
      Okitsu Y, Takahashi S, Minegishi N, Kameoka J, Kaku M, Yamamoto M, Sasaki T, and Harigae H
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 383-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo [4,5-f] quinoline.2007

    • Author(s)
      Kitamura Y, Umemura T, Kanki K, Kodama Y, Kitamoto S, Saito K, Itoh K, Yamamoto M, Masegi T, Nishikawa A, and Hirose M.
    • Journal Title

      Cancer Sci. 98

      Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Loss of p62/SQSTM1 suppresses cytoplasmic inclusion body formation and liver injury in autophagy-deficient mouse.2007

    • Author(s)
      Komatsu M, Waguri S, Koike M, Sou Y, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E and Tanaka K
    • Journal Title

      Cell. 131

      Pages: 1149-1163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.2007

    • Author(s)
      Reddy NM, Kleeberger SR, Cho H-Y, Yamamoto M, Kensler TW, Biswal S, and Reddy SP.
    • Journal Title

      Am J Res Cell Mol Biol. 37

      Pages: 3-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Dynamic regulation of Gata factor levels is more important than their identity.2007

    • Author(s)
      Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindern M, Ohneda K, Grosveld F, Yamamoto M, and Philipsen S.
    • Journal Title

      Blood. 109

      Pages: 5481-5490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Use of gene manipulated mice in the study of erythropoietin gene expression.2007

    • Author(s)
      Suzuki N, Obara N, and Yamamoto M.
    • Journal Title

      Methods Enzymol. 435

      Pages: 157-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.2007

    • Author(s)
      Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, . Chen YT, Chang C, Yamamoto M, Tanimoto K, Engel JD.
    • Journal Title

      EMBO J. 26

      Pages: 2295-2306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.2007

    • Author(s)
      Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim K-C, and Engel JD.
    • Journal Title

      Development. 139

      Pages: 1703-1712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Shear stress stabilizes NF-E2 related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species.2007

    • Author(s)
      Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, Ihsii T, Kodama T, and Noguchi N.
    • Journal Title

      Free Rad Biol Med. 42

      Pages: 260-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] The TR2 and TR4 orphan nuclear receptors repress Gatal transcription.2007

    • Author(s)
      Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, and Engel JD.
    • Journal Title

      Genes Dev. 21

      Pages: 2832-2844

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Oxidative and electrophilic stress induces Mrp transporters via the Nrf2 transcriptional pathway.2007

    • Author(s)
      Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, dalton TP, Yamamoto M, and Klaassen CD.
    • Journal Title

      Hepatology. 46

      Pages: 1597-1610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] GATA-1 self-association controls erythroid development in vivo.2007

    • Author(s)
      Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 15862-15871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Loss of p62/SQSTM1 suppresses cytoplasmic inclusion body formation and liver injury in autophagy-deficient mouse2007

    • Author(s)
      Komatsu M, Waguri S, Koike M, Sou Y, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K
    • Journal Title

      Cell 131

      Pages: 1149-1163

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] The TR2 and TR4 orphan nuclear receptors repress Gatal transcription.2007

    • Author(s)
      Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, and Engel JD.
    • Journal Title

      Genes Dev. 21

      Pages: 2832-2844

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA因子スイッチングとGATA-1白血病2007

    • Author(s)
      清水律子、山本雅之
    • Journal Title

      生化学 79

      Pages: 941-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Characterization of GATA-1^+ hemangioblastic cells in the mouse embryo.2007

    • Author(s)
      Yokomizo T, Takahashi S, Mochizuki N, Kuroha T, Ema M, Wakamatsu A, Shimizu R, Ohneda O, Osato M, Okada H, Komori T, Ogawa M, Nishikawa S, Ito Y, and Yamamoto M.
    • Journal Title

      EMBO J. 26

      Pages: 184-196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.2007

    • Author(s)
      Iida K, Itoh K, Maher JM, Kumagai Y, Oyasu R, Mori Y, Fukushima S, Shimazui T, Akaza H, and Yamamoto M.
    • Journal Title

      Carcinogenesis. 28

      Pages: 2398-2403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Characterization of GATA-1^+ hemangioblastic cells in the mouse embryo.2007

    • Author(s)
      Yokomizo T, Takahashi S, Mochizuki N, Kuroha T, Ema M, Wakamatsu A, Shimizu R, Ohneda O, Osato M, Okada H, Komori T, Ogawa M, Nishikawa S, Ito Y, and Yamamoto M.
    • Journal Title

      EMBO J. 26

      Pages: 184-196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, Yamamoto M
    • Journal Title

      Mol Cell Biol 27

      Pages: 7511-7521

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Different Electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, and Yamamoto M.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7511-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.2007

    • Author(s)
      Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YT, Chang C, Yamamoto M, Tanimoto K, Engel JD.
    • Journal Title

      EMBO J. 26

      Pages: 2295-2306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Subcellul localization and cytoplasmic complex status of endogenous Keapl.2007

    • Author(s)
      Watai Y, Kobayashi A, Nagase H, Mizukami M, McEvoy J, Singer JD, Itoh K, and Yamamoto M.
    • Journal Title

      Genes Cells. 12

      Pages: 1163-1178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Shear stress stabilizes NF-E2 related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species.2007

    • Author(s)
      Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, Ishii T, Kodama T, and Noguchi N.
    • Journal Title

      Free Rad Biol Med. 42

      Pages: 260-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer2007

    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, Yamamoto M
    • Journal Title

      J Biol Chem 282

      Pages: 33681-33690

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] 酸素センシングと赤血球造血シグナル2007

    • Author(s)
      今川重彦、小原 直、鈴木教郎、山本雅之
    • Journal Title

      細胞 39

      Pages: 537-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007

    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M.
    • Journal Title

      JBiol Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007

    • Author(s)
      Motohashi H, and Yamamoto M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.2007

    • Author(s)
      Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, and Kensler TW.
    • Journal Title

      Mol Cancer Therapeutics. 6

      Pages: 154-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Subcellul localization and cytoplasmic complex status of endogenous Keapl.2007

    • Author(s)
      Watai Y, Kobayashi A, Nagase H, Mizukami M, McEvoy J, Singer JD, Itoh K, and Yamamoto M.
    • Journal Title

      Genes Cells. 12

      Pages: 1163-1178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22)acute myeloid leukemia.2007

    • Author(s)
      Asou N, Yanagida M, Huang L, Yamamoto M, Shigesada K, Mitsuya H, Ito Y, and Osato M.
    • Journal Title

      Blood. 109

      Pages: 4023-4027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Enhanced spontaneous and benzo [α] pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.2007

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T and Yamamoto M.
    • Journal Title

      Cancer Res. 67

      Pages: 5643-5648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.2007

    • Author(s)
      Osbum WO, Karim B, Dolan PM, Liu G, Yamamoto M, Huso DL, and Kensler TW.
    • Journal Title

      Int J Cancer. 121

      Pages: 1883-1891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Dynamic regulation of Gata factor levels is more important than their identity.2007

    • Author(s)
      Ferreira R, Wai A, Shimizu R, Gillemans N, Rottier R, von Lindem M, Ohneda K, Grosveld F, Yamamoto M, and Philip sen S.
    • Journal Title

      Blood. 109

      Pages: 5481-5490

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.2007

    • Author(s)
      Reddy NM, Kleeberger SR, Cho H-Y, Yamamoto M, Kensler TW, Biswal S, and Reddy SP.
    • Journal Title

      Am J Res Cell Mol Biol. 37

      Pages: 3-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Inchinkoto, an herbal medicine, and its ingredients dually exert Mrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in ratlivers.2007

    • Author(s)
      Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y and Suzuki H.
    • Journal Title

      Am J Physiol Gastrointestinal Liver Physiol. 295

      Pages: 1450-1463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007

    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Role of Nrf2 in protection against intracerebral hemorrhage injury in mice.2007

    • Author(s)
      Wang J, Fields J, Zhao C, Langer J, Thimmulappa RK, Kensler TW, Yamamoto M, Biswal S, and Dore S.
    • Journal Title

      Free Rad Biol Med. 43

      Pages: 408-414

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] 食物と酸素由来の環境ストレスを感知するセンサー系2007

    • Author(s)
      大辻摩希子、山本雅之
    • Journal Title

      細胞工学 12月号

      Pages: 1386-1390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A novel class of prolyl hydroxylase inhibitors induces angiogenesis and exerts organ protection against ischemia.2007

    • Author(s)
      Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M, van Ypersele de Strihou C, Hirayama N, and Miyata T.
    • Journal Title

      Arterioscler Thromb Vas Biol. 27

      Pages: 2548-2554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Increased colonic inflammatory injury and formation of aberrant crypt foci in Nrf2-deficient mice upon dextran sulfate treatment.2007

    • Author(s)
      Osburn WO, Karim B, Dolan PM, Liu G, Yamamoto M, Huso DL, and Kensler TW.
    • Journal Title

      Int J Cancer. 121

      Pages: 1883-1891

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] A novel class of proly1 hydroxylase inhibitors induces angiogenesis and exerts or gan protection against ischemia.2007

    • Author(s)
      Nangaku M, Izuhara Y, Takizawa S, Yamashita T, Fujii-Kuriyama Y, Ohneda O, Yamamoto M, van Ypersele de Strihou C, Hirayama N, and Miyata T.
    • Journal Title

      Arterioscler Thromb Vas Biol. 27

      Pages: 2548-2554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] In vivo promoter analysis on refeeding response of hepatic sterol regulatory element-binding protein-1c expression.2007

    • Author(s)
      Takeuchi Y, Yahagi N, Nakagawa Y, Matsuzaka T, Shimizu R, Sekiya M, Iizuka Y, Ohashi K, Gotoda T, Yamamoto M, Nagai R, Kadowaki T, Yamada N, Osuga JI, and Shimano H.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 329-335

    • NAID

      120007139072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.2007

    • Author(s)
      Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, and Kensler TW.
    • Journal Title

      Mol Cancer Therapeutics. 6

      Pages: 154-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Potential involvement of pathophysiologically formed 8-nitroguanosine 3', 5'-cyclic monophosphate in nitric oxide-induced signal transduction.2007

    • Author(s)
      Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, and Akaike T.
    • Journal Title

      Nature Chem Biol. 3

      Pages: 727-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Regulation of GATAI gene expression.2007

    • Author(s)
      Kobayashi M, and Yamamoto M.
    • Journal Title

      J Biochem. 142

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] 食物と酸素由来の環境ストレスを感知するセンサー系2007

    • Author(s)
      大辻摩希子、山本雅之
    • Journal Title

      細胞工学 12月号

      Pages: 1386-1390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Dysfunction of Nrf2 decreases KBrO_3-induced oxidative DNA damage in Oggl-null mice.2007

    • Author(s)
      Jaloszynski P, Murata S, Shinkai Y, Takahashi S, Kumagai Y, Nishimura S, and Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 966-971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes2007

    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, Yamamoto M
    • Journal Title

      Biochem J 404

      Pages: 459-466

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Carcinogenesis and transcriptional regulation through Maf recognition elements.2007

    • Author(s)
      Motohashi H, and Yamamoto M.
    • Journal Title

      Cancer Sci. 98

      Pages: 135-139

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] GATA-1 self-association controls erythroid development in vivo.2007

    • Author(s)
      Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 15862-15871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Deficiency in Nrf2-GSH signaling impairs type II cell growth and enhances sensitivity to oxidants.2007

    • Author(s)
      Reddy NM, Kleeberger SR, Cho H-Y, Yamamoto M, Kensler TW, Biswal S, and Reddy SP.
    • Journal Title

      Am J Res Cell Mol Biol. 37

      Pages: 3-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Inchinkoto, an herbal medicine, and its ingredients dually exertMrp2/MRP2-mediated choleresis and Nrf2-mediated antioxidative action in ratlivers.2007

    • Author(s)
      Okada K, Shoda J, Kano M, Suzuki S, Ohtake N, Yamamoto M, Takahashi H, Utsunomiya H, Oda K, Sato K, Watanabe A, Ishii T, Itoh K, Yamamoto M, Yokoi T, Yoshizato K, Sugiyama Y and Suzuki H.
    • Journal Title

      Am J Physiol Gastrointestinal Liver Physiol. 295

      Pages: 1450-1463

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Potential involvement of pathophysiologically formed 8-nitorguanosine 3', 5'-cyclic monophosphate in nitric oxide-induced signal transduction2007

    • Author(s)
      Sawa T, Zaki MH, Okamoto T, Akuta T, Tokutomi Y, Kim-Mitsuyama S, Ihara H, Kobayashi A, Yamamoto M, Fujii S, Arimoto H, Akaike T
    • Journal Title

      Nature Chem Biol 3

      Pages: 727-735

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA-1 self-association controls erythroid development in vivo.2007

    • Author(s)
      Shimizu R, Trainor CD, Nishikawa K, Kobayashi M, Ohneda K, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 15862-15871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Does K-11706 enhance performance and why?2007

    • Author(s)
      Imagawa S, Matsumoto K, Horie M, Ohkoshi N, Nagasawa T, Doi T, Suzuki N, and Yamamoto M.
    • Journal Title

      Int J Sports Med. 28

      Pages: 928-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] 酸化ストレス防御のための生体内センサー:Keap1-Nrf2制御システム2007

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      化学と生物 45

      Pages: 857-862

    • NAID

      10019973647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Regulation of GATA1 gene expression.2007

    • Author(s)
      Kobayashi M, and Yamamoto M.
    • Journal Title

      J Biochem. 142

      Pages: 1-10

    • NAID

      10020097555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cell cycle-dependent oscillation of GATA2 expression in hematopoietic cells.2007

    • Author(s)
      Koga S, Yamaguchi N, Abe T, Minegishi M, Tsuchiya S, Yamamoto M, and Minegishi N.
    • Journal Title

      Blood. 109

      Pages: 4200-4208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes.2007

    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
    • Journal Title

      Biechem J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Molecular basis distinguishing the DNA binding profile of NRF2-MAF heterodimer from that of MAF homodimer.2007

    • Author(s)
      Kimura M, Yamamoto T, Zhang J, Itoh K, Kyo M, Kamiya T, Aburatani H, Katsuoka F, Kurokawa H, Tanaka T, Motohashi H, and Yamamoto M.
    • Journal Title

      J Biol Chem. 282

      Pages: 33681-33690

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Use of gene manipulated mice in the study of erythropoietin gene expression.2007

    • Author(s)
      Suzuki N, Obara N, and Yamamoto M.
    • Journal Title

      Methods Enzymol. 435

      Pages: 157-177

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] A Gata2 intronic enhancer confers its pan-endothelia-specific regulation.2007

    • Author(s)
      Khandekar M, Brandt W, Zhou Y, Dagenais S, Glover TW, Suzuki N, Shimizu R, Yamamoto M, Lim K-C, and Engel JD.
    • Journal Title

      Development. 139

      Pages: 1703-1712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Subcellul localization and cytoplasmic complex status of endogenous Keapl.2007

    • Author(s)
      Watai Y, Kobayashi A, Nagase H, Mizukami M, McEvoy J, Singer JD, Itoh K, and Yamamoto M.
    • Journal Title

      Genes Cells. 12

      Pages: 1163-1178

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] The N-terminal homology box 1(NHB1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its Asn-glycosylation.2007

    • Author(s)
      Zhang Y, Lucocq JM, Yamamoto M, and Hayes JD.
    • Journal Title

      Biochem J. 408

      Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Cell cycle-dependent oscillation of GATA2 expression in hematopoietic cells.2007

    • Author(s)
      Koga S, Yamaguclu N, Abe T, Minegishi M, Tsuchiya S, Yamamoto M, and Minegishi N.
    • Journal Title

      Blood. 109

      Pages: 4200-4208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Does K-11706 enhance performance and why?2007

    • Author(s)
      Imagawa S, Matsumoto K, Horie M, Ohkoshi N, Nagasawa T, Doi T, Suzuki N, and Yamamoto M.
    • Journal Title

      Int J Sports Med. 28

      Pages: 928-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response2007

    • Author(s)
      Tong KI, Padmanabhan B, Kobayashi A, Shang C, Hirotsu Y, Yokoyama S, Yamamoto M.
    • Journal Title

      Mol Cell Biol 27

      Pages: 7511-7521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Functional polymorphisms in the transcription factor NRF2 increase the risk of acute lung injury.2007

    • Author(s)
      Marzec JM, Christie JD, Reddy SP, Jedlicka AE, Vuong H, Lanken PN, Aplenc R, Yamamoto T, Yamamoto M, Cho, H-Y, and Kleeberger SR.
    • Journal Title

      FASEB J. 21

      Pages: 2237-2246

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] NRF2 modulates ary1 hydrocarbon receptor signaling: Influence on adipogenesis.2007

    • Author(s)
      Shin S, Wakabayashi N, Misra V, Biswal S, Lee GH, Agoston ES, Yamamoto M, and Kensler TW.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7188-7197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA因子スイッチングとGATA-1白血病2007

    • Author(s)
      清水律子、山本雅之
    • Journal Title

      生化学 79

      Pages: 941-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Enhanced spontaneous and benzo[α]pyrene-induced mutations in the lung of Nrf2-deficient gpt delta mice.2007

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T and Yamamoto M.
    • Journal Title

      Cancer Res. 67

      Pages: 5643-5648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 酸素センシングと赤血球造血シグナル2007

    • Author(s)
      今川重彦、小原 直、鈴木教郎、山本雅之
    • Journal Title

      細胞 39

      Pages: 537-540

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 and p53 cooperatively protect agahlst BBN-induced urinary bladder carcinogensis.2007

    • Author(s)
      Iida K, Itoh K, Maher JM, Kumagai Y, Oyasu R, Mori Y, Fukushima S, Shimazui T, Akaza H, and Yamamoto M.
    • Journal Title

      Carcinogenesis. 28

      Pages: 2398-2403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] The TR2 and TR4 orphan nuclear receptors repress Gatal transcription.2007

    • Author(s)
      Tanabe O, Shen Y, Liu Q, Campbell AD, Kuroha T, Yamamoto M, and Engel JD.
    • Journal Title

      Genes Dev. 21

      Pages: 2832-2844

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.2007

    • Author(s)
      Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, and Kumagai Y.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 645-650

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] The N-terminal homology box 1 (NHB1) sequence in transcription factor Nrf1 is required to anchor it to the endoplasmic reticulum and also to enable its Asn-glycosylation.2007

    • Author(s)
      Zhang Y, Lucocq JM, Yamamoto M, and Hayes JD.
    • Journal Title

      Biochem J. 408

      Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 酸化ストレス防御のための生体内センサー:Keap1-Nrf2制御システム2007

    • Author(s)
      田口恵子、山本雅之
    • Journal Title

      化学と生物 45

      Pages: 857-862

    • NAID

      10019973647

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Loss of p62/SQSTM1 suppresses cytoplasmic inclusion body formation and liver injury in autophagy-deficient mouse.2007

    • Author(s)
      Komatsu M, Waguri S, Koike M, Sou Y, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E and Tanak
    • Journal Title

      Cell. 131

      Pages: 1149-1163

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis2007

    • Author(s)
      Iida K, Itoh K, Maher JM, Kumagai Y, Oyasu R, Mori Y, Fukushima S, Shimazui T, Akaza H, Yamamoto M
    • Journal Title

      Carcinogenesis 28

      Pages: 2398-2403

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Shear stress stabilizes NF-E2 related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species.2007

    • Author(s)
      Warabi E, Takabe W, Minami T, Inoue K, Itoh K, Yamamoto M, Ishii T, Kodama T, and Noguchi N.
    • Journal Title

      Free Rad Biol Med. 42

      Pages: 260-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] NRF2 modulates aryl hydrocarbon receptor signaling: Influence on adipogenesis.2007

    • Author(s)
      Shin S, Wakabayashi N, Miss V, Biswal S, Lee GH, Agoston ES, Yamamoto M, and Kensler TW.
    • Journal Title

      Mol Cell Biol. 27

      Pages: 7188-7197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Embryonic and fetal beta-globin gene repression by the orphan nuclear receptors, TR2 and TR4.2007

    • Author(s)
      Tanabe O, McPhee D, Kobayashi S, Shen Y, Brandt W, Jiang X, Campbell AD, Chen YT, Chang C, Yamamoto M, Tanimoto K, Engel JD.
    • Journal Title

      EMBO J. 26

      Pages: 2295-2306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] GATA因子スイッチングとGATA-1白血病2007

    • Author(s)
      清水律子、山本雅之
    • Journal Title

      生化学 79

      Pages: 941-952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] 食物と酸素由来の環境ストレスを感知するセンサー系2007

    • Author(s)
      大辻摩希子、山本雅之
    • Journal Title

      細胞工学 12月号

      Pages: 1386-1390

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] The N-terminal homology box 1 (NHB1) sequence in transcription factor Nrfl is required to anchor it to the endoplasmic reticulum and also to enable its Asn-glycosylation.2007

    • Author(s)
      Zhang Y, Lucocq JM, Yamamoto M, and Hayes JD.
    • Journal Title

      Biochem J. 408

      Pages: 161-172

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Dysfunction of Nrf2 decreases KBrO_3-induced oxidative DNA damage in Ogg1-null mice.2007

    • Author(s)
      Jaloszynsk P, Murata S, Shinkai Y, Takahashi S, Kumagai Y, Nishimura S, and Yamamoto M.
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 966-971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Increased susceptibility to hepatocarcinogenicity of Nrf2-deficient mice exposed to 2-amino-3-methylimidazo[4,5-f] quinoline.2007

    • Author(s)
      Kitamura Y, Umemura T, Kanki K, Kodama Y, Kitamoto S, Saito K, Itoh K, Yamamoto M, Masegi T, Nishikawa A, and Hirose M.
    • Journal Title

      Cancer Sci. 98

      Pages: 19-24

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Subcellul localization and cytoplasmic complex status of endogenous Keap12007

    • Author(s)
      Watai Y, Kobayashi A, Nagase H, Mizukami M, McEvoy J, Singer JD, Itoh K, Yamamoto M
    • Journal Title

      Genes Cells 12

      Pages: 1163-1178

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Oxidative and electrophilic stress induces Mrp transporters via the Nrf2 transcriptional pathway.2007

    • Author(s)
      Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, and Klaassen CD.
    • Journal Title

      Hepatology. 46

      Pages: 1597-1610

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Journal Article] Regulation of GATA1 gene expression.2007

    • Author(s)
      Kobayashi M, and Yamamoto M.
    • Journal Title

      J Biochem. 142

      Pages: 1-10

    • NAID

      10020097555

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 Neh5 domain is differentially utilized in the transactivation of cytop rotective genes.2007

    • Author(s)
      Zhang J, Hosoya T, Maruyama A, Nishikawa K, Maher JM, Ohta T, Motohashi H, Fukamizu A, Shibahara S, Itoh K, and Yamamoto M.
    • Journal Title

      Biochem J. 404

      Pages: 459-466

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Regulation of adipocyte differentiation of bone marrow stromal cells by transcription factor GATA-2.2007

    • Author(s)
      Okitsu Y, Takahashi S, Minegishi N, Kameoka J, Kaku M, Yamamoto M, Sasaki T, and Harigae H
    • Journal Title

      Biochem Biophys Res Commun. 364

      Pages: 383-387

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Does K-11706 enhance performance and why?2007

    • Author(s)
      Imagawa S, Matsumoto K, Horie M, Ohkoshi N, Nagasawa T, Doi T, Suzuki N, and Yamamoto M.
    • Journal Title

      Int J Sports Med. 28

      Pages: 928-933

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Journal Article] Enhanced spontaneous and benzo[a]pyrene- induced mutations in the lung of Nrf2-deficient gpt delta mice2007

    • Author(s)
      Aoki Y, Hashimoto AH, Amanuma K, Matsumoto M, Hiyoshi K, Takano H, Masumura K, Itoh K, Nohmi T, Yamamoto M
    • Journal Title

      Cancer Res 67

      Pages: 5643-5648

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006

    • Author(s)
      Yamamoto, T., et al.
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a 'tethering' mechanism : A two-site interaction model for the Nrf2-Keapl complex.2006

    • Author(s)
      McMahon MJ, Thomas N, Itoh K, Yamamoto M, Hayes JD.
    • Journal Title

      J Biol Chem 281(34)

      Pages: 24756-24768

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] MafG sumoylation is required for active transcriptional repression.2006

    • Author(s)
      Motohashi H, Katsuoka F, Miyoshi C, Uchimura Y, Saitoh H, Francastel C, Engel JD, Yamamoto M.
    • Journal Title

      Mol Cell Biol 26(12)

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Structural basis for defects of Keapl activity provoked by its point mutations in lung cancer.2006

    • Author(s)
      B.Padmanabhan, M.Yamamoto et al.(total 10, last)
    • Journal Title

      Mol. Cell 21(5)

      Pages: 689-700

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] MafG sumoylation is required for active transcriptional repression2006

    • Author(s)
      Motohashi H, Katsuoka F, Miyoshi C, Uchimura Y, Saitoh H, Francastel C, Engel JD, Yamamoto M
    • Journal Title

      Mol Cell Biol

      Pages: 4652-4663

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer.2006

    • Author(s)
      B.Padmanabhan, M.Yamamoto et al.(total 10, last)
    • Journal Title

      Mol.Cell 21(5)

      Pages: 1-12

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model2006

    • Author(s)
      Tong KI, Katoh Y, Kusunoki H, Itoh K, Tanaka T, Yamamoto M
    • Journal Title

      Mol Cell Biol 26

      Pages: 2887-2900

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Nrf2 is a critical regulator of innate immune response and survival during experimental sepsis.2006

    • Author(s)
      Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S.
    • Journal Title

      J Clin Invest 116(4)

      Pages: 984-995

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] BRG1 Interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress2006

    • Author(s)
      Zhang J, Ohta T, Maruyama A, Hosoya T, Nishikawa K, Maher JM, Shibahara S, Itoh K, Yamamoto M
    • Journal Title

      Mol Cell Biol 26

      Pages: 7942-7952

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Unique and overlapping transcriptional roles of Arnt (Arylhydrocarbon receptor nuclear translocator) and Arnt2 in xenobiotic and hypoxic responses.2006

    • Author(s)
      Sekine H, Mimura J, Yamamoto M, Fujii-Kuriyama Y.
    • Journal Title

      J Biol Chem 281(49)

      Pages: 37507-37516

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements2006

    • Author(s)
      Yamamoto T, Kyo M, Kamiya T, Tanaka T, Engel JD, Motohashi M, Yamamoto M
    • Journal Title

      Genes Cells 11

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Negative regulation of Nrf1 (nuclear factor-erythroid 2 p45-related factor 1) its N-terminal domain is independent of Keapl : The Nrf1 and Nrf2 transcription factors are located to different sub-cellular compartments and are negatively controlled by distinct mechanisms.2006

    • Author(s)
      Zhang Y, Crouch DH, Yamamoto M, Hayes JD.
    • Journal Title

      Biochem J 399

      Pages: 373-385

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Predictive base substitution rules that determine the binding and transcriptional specificity of Maf recognition elements.2006

    • Author(s)
      Yamamoto T, Kyo M, Kamiya T, Tanaka T, Engel JD, Motohashi M, Yamamoto M.
    • Journal Title

      Genes Cells 11(6)

      Pages: 575-591

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species2006

    • Author(s)
      Kobayashi M, Yamamoto M
    • Journal Title

      Adv Enz Regl Elsevier Science B.V., New York vol.46

      Pages: 113-140

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Two-site substrate recognition model for the Keap1-Nrf2 System: a hinge and latch mechanism2006

    • Author(s)
      Tong KI, Kobayashi A, Katsuoka F, Yamamoto M
    • Journal Title

      Biol Chem 387

      Pages: 1311-1320

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] A crucial role of Nrf2 in vivo in defense against oxidative damage by an environmental pollutant, pentachlorophenol.2006

    • Author(s)
      Umemura T, Kuroiwa Y, Kitamura Y, Ishii Y, Kanki K, Kodama Y, Itoh K, Yamamoto M, Nishikawa A, Hirose M.
    • Journal Title

      Toxicol Sci 90(1)

      Pages: 111-119

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] BRG1 Interacts with Nrf2 to selectively mediate HO-1 induction in response to oxidative stress.2006

    • Author(s)
      Zhang J, Ohta T, Maruyama A, Hosoya T, Nishikawa K, Maher JM, Shibahara S, Itoh K, Yamamoto M.
    • Journal Title

      Mol Cell Biol. 26(21)

      Pages: 7942-7952

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Tissue Prx I in the protection against Fe-NTA and the reduction of nitroxyl radicals.2006

    • Author(s)
      Uwayama J, Hirayama A, Yanagawa T, Warabi E, Sugimoto R, Itoh K, Yamamoto M, Yoshida H, Koyama A, Ishii T.
    • Journal Title

      Biochem Biophys Res Commun 339(1)

      Pages: 226-231

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Nrf2 controls bone marrow stromal cell susceptibility to oxidative and electrophilic stress.2006

    • Author(s)
      Zhu H, Zhang L, Itoh K, Yamamoto M, Ross D, Trush MA, Zweier JL, Li Y
    • Journal Title

      Free Rad Biol Med 41(1)

      Pages: 132-143

    • Data Source
      KAKENHI-PROJECT-17390088
  • [Journal Article] Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer2006

    • Author(s)
      Padmanabhan B, Tong KI, Ohta T, Nakamura Y, Scharlock M, Ohtsuji M, Kang M-I, Kobayashi A, Yokoyama S, Yamamoto M
    • Journal Title

      Mol Cell 21

      Pages: 689-700

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Oxidative and electrophilic stresses activate Nrf2 through inhibition of ubiquitination activity of Keap12006

    • Author(s)
      Kobayashi A, Kang MI, Watai Y, Tong KI, Shibata T, Uchida K, Yamamoto M
    • Journal Title

      Mol Cell Biol 26

      Pages: 221-229

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] The distal sequence element of the selenocysteine tRNA gene is a tissue-dependant enhancer essential for mouse embryogenesis2005

    • Author(s)
      Kelly VP, Suzuki T, Nakajima O, Arai T, Tamai Y, Takahashi S, Nishimura S, Yamamoto M
    • Journal Title

      Mol Cell Biol 25

      Pages: 3658-3669

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome.2005

    • Author(s)
      Katoh, Y., Iida, K., Kang, M-I., Kobayashi, A., Mizukami, M., Tong, K.I., McMahon, M., Hayes, J.D., Itoh, K., Yamamoto, M.
    • Journal Title

      Arch.Biochem.Biophys. 433

      Pages: 342-350

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Restricted expression of constitutively active-aryl hydrocarbon receptor in T lineage cells causes thymus involution and suppresses the immunization-induced splenocyte increase.2005

    • Author(s)
      Nohara, K., Pan, X., Tsukumo, S., Hida, A., Ito, T., Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Tohyama, C.
    • Journal Title

      J.Immunol (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element2005

    • Author(s)
      Katsuoka F, Motohashi M, Engel JD, Yamamoto M
    • Journal Title

      J Biol Chem 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] UVA irradiation induces Nrf2 activation in dermal fibroblasts : Protective role in UVA-induced apoptosis.2005

    • Author(s)
      Hirota, A., Kawachi, Y., Itoh, K., Nakamura, Y., Xu, X., Banno, T., Takahashi, T., Yamamoto, M, Ohtsuka, F.
    • Journal Title

      Invest.Dermatol. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.2005

    • Author(s)
      Padmanabhan, B., Scharlock, M., Tong, K.I., Nakamura, Y., Kang, M-I., Kobayashi, A., Matsumoto, T., Tanaka, A., Yamamoto, M., Yokoyama, S.
    • Journal Title

      Acta Crystallographica 61

      Pages: 153-155

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Gene expression regulation and domain function of hematopoietic GATA factors.2005

    • Author(s)
      Shimizu, R., Yamamoto, M.
    • Journal Title

      Seminars in Cell & Developmental Biology 16

      Pages: 129-136

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Restricted expression of constitutively active-aryl hydrocarbon receptor in T lineage cells causes thymus involution and suppresses immunization-induced splenocyte increase.2005

    • Author(s)
      Nohara, K, Pan, X., Tsukumo, S., Hida, A., Ito, T., Nagai, H., Inouye, K., Motohashi, H., Yamamoto, M., Fujii-Kudyama, Y, Tohyama, C.
    • Journal Title

      J.Immunol (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Transgenic overexpression of GATA-1 mutant lacking N-finger domain causes hemolytic syndrome in mouse erythroid cells.2005

    • Author(s)
      Nakano, M., Ohneda, K., Mukai, H.Y., Shimizu, R., Ohneda, O., Ohmura, S., Suzuki, M., Tsukamoto, S., Yanagawa, T., Yoshida, H., Takakuwa, Y, Yamamoto, M.
    • Journal Title

      Genes Cells 10

      Pages: 47-62

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] The distal sequence element of the selenocysteine tRNA gene is a tissue dependent enhancer essential for mouse embryogenesis.2005

    • Author(s)
      Kelly, V.P., Suzuki, T., Nakajima, O., Arai, T., Tamai, Y., Takahashi, S., Nishimura, S., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005

    • Author(s)
      Katsuoka, F., Motohashi, H., Engel, J.D., Yamamoto, M.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Molecular mechanisms activating Nrf2-Keap1 pathway in regulation of antioxidant gene.2005

    • Author(s)
      Kobayashi, M, Yamamoto, M.
    • Journal Title

      Antioxidants Redox Signaling 7

      Pages: 384-395

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells2005

    • Author(s)
      Hosoya T, Maruyama A, Kang M-i, Kawatani Y, Shibata T, Uchida K, Itoh K, Yamamoto M
    • Journal Title

      J Biol Chem 280

      Pages: 27244-27250

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Molecular mechanisms activating Nrf2-Keap1 pathway in regulation of antioxidant genes.2005

    • Author(s)
      Kobayashi, M., Yamamoto, M.
    • Journal Title

      Antioxidants Redox Signaling 7

      Pages: 384-395

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions2005

    • Author(s)
      Tauchi M, Hida A, Negishi T, Katsuoka F, Noda S, Mimura J, Hosoya H, Yanaka A, Aburatani H, Fujii-Kuriyama Y, Motohashi H, Yamamoto M
    • Journal Title

      Mol Cell Biol 25

      Pages: 9360-9368

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] The distal sequence element of the selenocysteine tRNA gene is a tissue dependant enhancer essential for mouse embryogenesis.2005

    • Author(s)
      Kelly, V.P., Suzuki, T., Nakajima, O., Arai, T., Tamai, Y., Takahashi, S., Nishimura.S, Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Nrf2 transcriptionally activates the mafG gene through an antioxidant response element.2005

    • Author(s)
      Katsuoka, F., Motohashi, M., Engel, J.D., Yamamoto, M.
    • Journal Title

      J.Biol.Chem. 280

      Pages: 4483-4490

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] GATA1 function, a paradigm for transcription factors in hematopoiesis.2005

    • Author(s)
      Ferreira, R., Ohneda, K., Yamamoto, M., Philipsen, S.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 1215-1217

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Role of 15-deoxyD^<12-14> Prostaglandin J_2 and Nrf2 Pathways in Protection against Acute Lung Injury.2005

    • Author(s)
      Mochizuki, M., Ishii, Y., Itoh, K., Iizuka, T., Morishima, Y., Kimura, T., Kiwamoto, T., Matsuno, Y., Hegab, A.E., Nomura, A., Sakamoto, T., Uchida, K., Yamamoto, M., Sekizawa, K.
    • Journal Title

      Am.J.Res.Cri.Care Med (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Enhanced erythropoiesis mediated by activation of the renin-angiotensin system via angiotensin II type la receptor.2005

    • Author(s)
      Kato H, Ishida J, Imagawa S, Saito T, Suzuki N, Matsuoka T, Sugaya T, Tanimoto K, Yokoo T, Ohneda O, Sugiyama F, Yagami K, Fujita T, Yamamoto M, Nangaku M, Fukamizu A.
    • Journal Title

      FASEB J 19

      Pages: 2023-2025

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590923
  • [Journal Article] Essential role of synoviolin in embryogenesis.2005

    • Author(s)
      Yagishita, N., Ohneda, K., Amano, T., Yamasaki, S., Sugiura, A., Tsuchimochi, K., Shin, H., Kawahara, K., Ohneda, O., Ohta, T., Tanaka, S., Yamamoto, M., Maruyama, I., Nishioka, K., Fukamizu, A., Nakajima, T.
    • Journal Title

      J.Biol.Chem. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Essential role of synoviolin in embryogenesis.2005

    • Author(s)
      Yagishita, N., Ohneda, K., Amano, T., Yamasaki, S., Sugiura, A., Tsuchimochi, K., Shin, H., Kawahara, K., Ohneda, O., Ohta, T., Tanaka, S., Yamamoto, M., Maruyama, I., Nishioka, K., Fukamizu, A., Nakajima, T.
    • Journal Title

      J.Biol.Chem (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish.2005

    • Author(s)
      Suzuki, T., Takagi, Y., Osanai, H., Li, L., Takeuchi, M., Katoh, Y., Kobayashi, M, Yamamoto, M
    • Journal Title

      Biochem.J. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Nrf2-deficient mice are highly susceptible to cigarette smoke-induced emphysema2005

    • Author(s)
      Iizuka T, Ishii Y, Itoh K, Kiwamoto T, Kimura T, Matsuno Y, Morishima Y, Hegab AE, Homma S, Nomura A, Sakamoto T, Shimura M, Yoshida A, Yamamoto M, Sekizawa K
    • Journal Title

      Genes Cells 10

      Pages: 1113-1125

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] UVA irradiation induces Nrf2 activation in dermal fibroblasts : Protective role in UVA-induced apoptosis.2005

    • Author(s)
      Hirota, A., Kawachi, Y., Itoh, K., Nakamura, Y., Xu, X., Banno, T., Takahashi, T., Yamamoto, M., Ohtsuka, F.
    • Journal Title

      Invest.Dermatol. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Purification, crystallization and preliminary X-ray diffraction analysis of the Kelch-like motif region of mouse Keap1.2005

    • Author(s)
      Padmanabhan, B., Scharlock, M, Tong, K.I, Nakamura, Y., Kang, M-I., Kobayashi, A., Matsumoto, T., Tanaka, A., Yamamoto, M, Yokoyama, S.
    • Journal Title

      Acta Crystallographica 61

      Pages: 153-155

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Role of the nrf-2 gene in protection and repair of gastric mucosa against oxidative stress2005

    • Author(s)
      Yanaka A, Zhang S, Tauchi M, Suzuki H, Shibahara T, Matsui H, Nakahara A, Tanaka N, Yamamoto M
    • Journal Title

      Inflammopharmacology 13

      Pages: 83-90

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keapl-mediated degradation of the protein by proteasome.2005

    • Author(s)
      Katoh, Y., Iida, K., Kang, M-I, Kobayashi, A., Mizukami, M., Tong, K.I., McMahon, M., Hayes, J.D., Itoh, K., Yamamoto, M.
    • Journal Title

      Arch.Biochem.Biophys. 433

      Pages: 342-350

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Pi class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish2005

    • Author(s)
      Suzuki T, Takagi Y, Osanai H, Li L, Takeuchi M, Katoh Y, Kobayashi M, Yamamoto M
    • Journal Title

      Biochem J 388

      Pages: 65-73

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.2005

    • Author(s)
      Ezoe, S., Matsumura, I., Gale, K., Satoh, Y., Ishikawa, J., Mizuki, M., Takahashi, S., Minegishi, N., Nakajima, K., Yamamoto, M., Enver, T., Kanakura, Y.
    • Journal Title

      J.Biol.Chem.

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Role of 15-deoxyD^<12-14> Prostaglandin J_2 and Nrf2 Pathways in Protection against Acute Lung Injury.2005

    • Author(s)
      Mochizuki, M., Ishii, Y., Itoh, K., Iizuka, T., Morishima, Y., Kimura, T., Kiwamoto, T., Matsuno, Y., Hegab, A.E., Nomura, A., Sakamoto, T., Uchida, K., Yamamoto, M, Sekizawa, K.
    • Journal Title

      Am.J.Res.Cri.Care Med (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Genetic evidence that small Maf proteins are essential for the activation of antioxidant response element-dependent genes2005

    • Author(s)
      Katsuoka F, Motohashi H, Ishii T, Aburatani H, Engel JD, Yamamoto M
    • Journal Title

      Mol Cell Biol 25

      Pages: 8044-8051

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Molecular mechanisms activating Nrf2-Keap1 pathway in regulation of antioxidant genes2005

    • Author(s)
      Kobayashi M, Yamamoto M
    • Journal Title

      Antioxidants Redox Signaling 7

      Pages: 384-395

    • Data Source
      KAKENHI-PROJECT-17013017
  • [Journal Article] Pi-class glutathione S-transferase genes are regulated by Nrf2 through an evolutionarily conserved regulatory element in zebrafish.2005

    • Author(s)
      Suzuki, T., Takagi, Y., Osanai, H., Li, L., Takeuchi, M., Katoh, Y., Kobayashi, M., Yamamoto, M.
    • Journal Title

      Biochem.J. (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] GATA1 function, a paradigm for transcription factors in hematopoiesis.2005

    • Author(s)
      Ferreira, R., Ohneda, K., Yamamoto, M., Philipsen, S.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 1215-1217

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity.2005

    • Author(s)
      Ezoe, S., Matsumura, I., Gale, K, Satoh, Y., Ishikawa, J., Mizuki, M., Takahashi, S., Minegishi, N., Nakajima, K, Yamamoto, M., Enver, T, Kanakura, Y.
    • Journal Title

      J.Biol.Chem.

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Transgenic overexpression of GATA-1 mutant lacking N-finger domain causes hemolytic syndrome in mouse erythroid cells.2005

    • Author(s)
      Nakano, M., Ohneda, K., Mukai, H.Y., Shimizu, R., Ohneda, O., Ohmura, S., Suzuki, M., Tsukamoto, S., Yanagawa, T., Yoshida, H., Takakuwa, Y., Yamamoto, M.
    • Journal Title

      Genes Cells 10

      Pages: 47-62

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Gene expression regulation and domain function of hematopoietic GATA factors.2005

    • Author(s)
      Shimizu, R, Yamamoto, M.
    • Journal Title

      Seminars in Cell & Developmental Biology 16

      Pages: 129-136

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Identification of polymorphisms in the promoter region of human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., et al.
    • Journal Title

      Biochem. Biophys. Res. Commun. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] The transcription factor Nrf2 protects against pulmonary fibrosis.2004

    • Author(s)
      Cho, H-Y., Reddy, S.P.M., Yamamoto, M., Kleeberger, S.R.
    • Journal Title

      FASEB J. 18

      Pages: 1258-1260

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr2004

    • Author(s)
      Morito, N., Yoh, K., Hirayama, A., Itoh, K., Nose, M., Koyama, A., Yamamoto, M.
    • Journal Title

      Kidney Int. 65

      Pages: 1703-1713

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2 Is Essential for the Chemopreventive Efficacy of Oltipraz against Urinary Bladder Carcinogenesis.2004

    • Author(s)
      Iida, K., Itoh, K., Kumagai, Y., Oyasu, R., Hattori, K., Kawai, K., Shimazui, T., Akaza, H., Yamamoto, M.
    • Journal Title

      Cancer Res. 64

      Pages: 6124-6431

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Do b-globin, GATA-1 or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?2004

    • Author(s)
      Suzuki, N., Imagawa, S., Noguchi C.T., Yamamoto, M.
    • Journal Title

      Blood 104

      Pages: 2968-2969

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.2004

    • Author(s)
      Itoh, K., Tong, K.I., Yamamoto, M.
    • Journal Title

      Free Radical Biol.Med. 36

      Pages: 1208-1121

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Nrf2 Is Essential for the Chemopreventive Efficacy of Oltipraz against Urinary Bladder Carcinogenesis.2004

    • Author(s)
      Iida, K., Itoh, K., Kumagai, Y., Oyasu, R., Hattori, K., Kawai, K., Shimazui, T., Akaza, H., Yamamoto, M.
    • Journal Title

      Cancer Res. 64

      Pages: 6124-6431

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages : activation by oxidatively modified LDL and 4-hydroxynonenal2004

    • Author(s)
      Ishii, T., Itoh, K., Ruiz, E., Leake, D.S., Unoki, H., Yamamoto, M., Mann, G.E.
    • Journal Title

      Circulation 94

      Pages: 609-616

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Role of Nrf2 in the regulation of CD36 and stress protein expression in murine macrophages : activation by oxidatively modified LDL and 4-hydroxynonenal2004

    • Author(s)
      Ishii, T., Itoh, K., Ruiz, E., Leake, D.S., Unoki, H., Yamamoto, M., Mann, G.E.
    • Journal Title

      Circulation 94

      Pages: 609-616

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes2004

    • Author(s)
      Kobayashi, A., Ohta, T., Yamamoto, M.
    • Journal Title

      Methods Enzymol. 378

      Pages: 1208-1213

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] GATA転写因子からみる赤血球の発生・分化2004

    • Author(s)
      長野真澄, 山本雅之
    • Journal Title

      実験医学 22

      Pages: 361-366

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.2004

    • Author(s)
      Kobayashi, A., Kang, M.I., Ohkawa, H., Ohtuji, M., Zenke, Y., Chiba, T., Igarashi, K., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 7310-7319

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.2004

    • Author(s)
      Yoshida, S., Takakura, A., Ohbo, K., Abe, K., Wakabayashi, J., Yamamoto, M., Suda, T., Nabeshima, Y-i.
    • Journal Title

      Dev.Biol. 269

      Pages: 447-458

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Keap1-Nrf2システムによる抗酸化酵素群の統一的発現制御機構2004

    • Author(s)
      細谷朋方, 山本雅之
    • Journal Title

      分子呼吸器病 8

      Pages: 147-150

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Identification of polymorphisms in the promoter region of human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] 転写因子と血液疾患2004

    • Author(s)
      峯岸直子, 山本雅之
    • Journal Title

      臨床検査 48

      Pages: 473-781

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Small Maf proteins are obligate transcriptional cofactors for normal keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway.2004

    • Author(s)
      Motohashi, H., Katsuoka, F., Engel, J.D., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 6379-6384

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Identification of polymorphisms in the promoter region of human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., Yoh, K., Kobayashi, K., Ishii, Y., Kure, S., Koyama, A., Sekizawa, K., Motohashi, H., Yamamoto, M.
    • Journal Title

      Biochem.Biophys.Res.Connnun. 321

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] In vivo and in vitro constant expression of GATA-4 in mouse postnatal Sertoli cells.2004

    • Author(s)
      Imai, T., Kawai, Y., Tadokoro, Y., Yamamoto, M., Nishimune, Y., Yomogida K.
    • Journal Title

      Mol.Cell.Endocrinol. 214

      Pages: 107-115

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Molecular mechanism activating Nrf2-Keap1 pathway in regulation of adaptive response to electrophiles.2004

    • Author(s)
      Itoh, K., Tong, K.I., Yamamoto, M.
    • Journal Title

      Free Radical Biol.Med. 36

      Pages: 1208-1213

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] The transcriptional program of antibody class switching involves the repressor Bach2.2004

    • Author(s)
      Muto, A., Tashiro, S., Nakajima, O., Hoshino, H., Takahashi, S., Sakoda, E., Ikebe, D., Yamamoto, M., Igarashi, K.
    • Journal Title

      Nature 429

      Pages: 566-571

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] GATA-1ノックダウンマウス2004

    • Author(s)
      清水律子, 山本雅之
    • Journal Title

      Mebio 21

      Pages: 58-62

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of Jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004

    • Author(s)
      Ito, T., Tsukumo, S., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 25204-25210

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] The transcription factor Nrf2 protects against pulmonary fibrosis.2004

    • Author(s)
      Cho, H-Y., Reddy, S.P.M., Yamamoto, M., Kleeberger, S.R.
    • Journal Title

      FASEB J. 18

      Pages: 1258-1260

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1b, TNF-a or L-NMMA.2004

    • Author(s)
      Imagawa, S., Nakano, Y., Obara, N., Suzuki, N., Doi, T., Kodama, T., Nagasawa, T., Yamamoto, M.
    • Journal Title

      Blood 104

      Pages: 4300-4307

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Leukemogenesis caused by incapacitated GATA-1 function.2004

    • Author(s)
      Shimizu, R., Kuroha, T., Ohneda, O., Pan, X., Ohneda, K., Takahashi, S., Philipsen, S., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 10814-10825

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Interleukin-6 and tumor necrosis factor a in patients with obstructive sleep apnea-hypopnea syndrome.2004

    • Author(s)
      Imagawa S, Yamaguchi Y, Ogawa K, Obara N, Suzuki N, Yamamoto Y, Nagasawa T.
    • Journal Title

      Respiration 71

      Pages: 24-29

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590923
  • [Journal Article] 親電子性物質応答の分子機構2004

    • Author(s)
      伊東 健, 山本雅之
    • Journal Title

      生化学 76

      Pages: 339-348

    • NAID

      10012894688

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Transcription factor Nrf2 is essential for induction of NAD(P)H : quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates.2004

    • Author(s)
      McWalter, G.K., Higgins, L.G., McLellan, L.I., Henderson, C.J., Song, L., Thomalley, P.J., Itoh, K., Yamamoto, M., Hayes, J.D.
    • Journal Title

      J.Nutr. 134

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity and restores indicators in an in vivo mouse model of anemia of chronic disease.2004

    • Author(s)
      Nakano Y, Imagawa S, Matsumoto K, Stockmann C, Obara N, Suzuki N, Doi T, Kodama T, Takahashi S, Nagasawa T, Yamamoto M.
    • Journal Title

      Blood 104

      Pages: 4300-4307

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590923
  • [Journal Article] Do β-globin, GATA-1 or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?2004

    • Author(s)
      Suzuki N, Imagawa S, Noguchi CT, Yamamoto M, Klingmuller U.
    • Journal Title

      Blood 104

      Pages: 2988-2989

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590923
  • [Journal Article] Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox sensitive Neh2 degron and the redox-insensitive Neh6 degron.2004

    • Author(s)
      McMahon, M., Thomas, N., Itoh, K., Yamamoto, M., Hayes, J.D.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 31556-31567

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.2004

    • Author(s)
      Kang, MI, Kobayashi, A., Wakabayashi, N., Kim, S.G., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 2046-2051

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Identification of polymorphisms in the promoter region of the human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., Yoh, K., Kobayashi, K., Ishii, Y., Kure, S., Koyama, A., Sekizawa, K., Motohashi, H., Yamamoto, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 321

      Pages: 72-79

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.2004

    • Author(s)
      Kobayashi, A., Kang, M.I., Ohkawa, H., Ohtuji, M., Zenke, Y., Chiba, T., Igarashi, K., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 7310-7319

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Transcription factor Nrf2 is essential for induction of NAD(P)H : quinone oxidoreductase 1, glutathione S-transferases, and glutamate cysteine ligase by broccoli seeds and isothiocyanates.2004

    • Author(s)
      McWalter, G.K., Higgins, L.G., McLellan, L.I., Henderson, C.J., Song, L., Thornalley, P.J., Itoh.K., Yamamoto, M., Hayes, J.D.
    • Journal Title

      J.Nutr. 134

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] MafT, a new member of the small Maf protein family in zebrafish.2004

    • Author(s)
      Takagi, Y., Kobayashi, M., Li, L., Suzuki, T., Nishikawa.K., Yamamoto, M.
    • Journal Title

      Biochem.Biophys.Res.Connnun. 320

      Pages: 62-69

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] An activator protein-1-Notch-4 angiogenic vascular remodeling pathway.2004

    • Author(s)
      Wu, J., Iwata, F., Grass, J.A., Elnitski, L., Ohneda, O., Yamamoto, M., Bresnick, E.H.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 1458-1474

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] GATA-1変異と白血病-転写因子の質的異常と量的異常2004

    • Author(s)
      長野真澄, 清水律子, 山本雅之
    • Journal Title

      医学の歩み 211

      Pages: 159-162

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] MafT, a new member of the small Maf protein family in zebrafish.2004

    • Author(s)
      Takagi, Y., Kobayashi, M., Li, L., Suzuki, T., Nishikawa, K., Yamamoto, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 320

      Pages: 62-69

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Multiple, distant Gata2 enhancers specify temporal and tissue-specific patterning in the developing urogenital system.2004

    • Author(s)
      Khandekar, M.J., Suzuki, N., Lewton, J., Yamamoto, M., Engel, J.D.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 10263-10276

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice.2004

    • Author(s)
      Rangasamy, T., Cho, C.Y., Thimmulappa, R.K., Zhen, L., Srisuma, S.S., Kensler, T.W., Yamamoto, M., Petrache, I., Tuder, R.M., Biswal, S.
    • Journal Title

      J.Clin.Invest 114

      Pages: 1248-1259

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004

    • Author(s)
      Motohashi, H., Yamamoto, M.
    • Journal Title

      Trends Mol.Med. 10

      Pages: 549-557

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Identification of polymorphisms in the promoter region of human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., et al.
    • Journal Title

      Biochem.Biophys.Res.Common. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Multiple, distant Gata2 enhancers specify temporal and tissue-specific patterning in the developing urogenital system.2004

    • Author(s)
      Khandekar, M.J., Suzuki, N., Lewton, J., Yamamoto, M., Engel, J.D.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 10263-10276

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Nrf2 deficiency improves autoimmune nephritis caused by the fas mutation lpr2004

    • Author(s)
      Morito, N., Yoh, K., Hirayama, A., Itoh, K., Nose, M., Koyama, A., Yamamoto, M.
    • Journal Title

      Kidney Int. 65

      Pages: 1703-1713

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Gene expression profiling of NRF2-mediated protection against oxidative injury.2004

    • Author(s)
      Cho, H-Y., Reddy, S.P., DeBiase, A., Yamamoto, M., Kleeberger, S.R.
    • Journal Title

      Free Rad.Biol.Med. 38

      Pages: 325-343

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice2004

    • Author(s)
      Rangasamy, T., Cho, C.Y., Thimmulappa, R.K, Zhen, L, Srisuma, S.S., Kensler, T.W., Yamamoto, M., Petrache, I., Tuder, R, M, Biswal, S.
    • Journal Title

      J.Clin.Invest 114

      Pages: 1248-1259

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Leukemogenesis caused by incapacitated GATA-1 function.2004

    • Author(s)
      M.Yamamoto.(他7名)
    • Journal Title

      Mol.Cell.Biol. 24(24)

      Pages: 10814-10825

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Nrf2 deficiency causes tooth decolourization due to iron transport disorder in enamel organ.2004

    • Author(s)
      Yanagawa, T., Itoh, K., Uwayama, J., Shibata, Y., Yamaguchi, A., Sano, T., Ishii, T., Yoshida, H., Yamamoto, M.
    • Journal Title

      Genes Cells 9

      Pages: 641-651

    • NAID

      120007131624

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 Mice.2004

    • Author(s)
      Goldring, C.E.P., Kitteringham, N.R., Elsby, R., Randle, L.E., Clement, Y.N., Williams, D.P., McMahon, M., Hayes, J.D., Itoh, K., Yamamoto, M., Park, B.K.
    • Journal Title

      Hepatology 39

      Pages: 1267-1276

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Identification of polymorphisms in the promoter region of human NRF2 gene.2004

    • Author(s)
      Yamamoto, T., et al.
    • Journal Title

      Biochem. Biophys. Res. Commum. 321

      Pages: 72-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] An activator protein-1-Notch-4 angiogenic vascular remodeling pathway.2004

    • Author(s)
      Wu, J., Iwata, F., Grass, J.A., Elnitski, L., Ohneda, O., Yamamoto, M., Bresnick, E.H.
    • Journal Title

      Mol.Cell.Biol. 25

      Pages: 1458-1474

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes.2004

    • Author(s)
      Kang, M.I., Kobayashi, A., Wakabayashi, N., Kim, S.G., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 2046-2051

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Do b-globin, GATA-1 or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?2004

    • Author(s)
      Suzuki, N., Imagawa, S., Noguchi C.T., Yamamoto, M.
    • Journal Title

      Blood 104

      Pages: 2968-2969

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis.2004

    • Author(s)
      M.Yamamoto.(他8名)
    • Journal Title

      Cancer Res. 64(18)

      Pages: 6124-6431

    • Data Source
      KAKENHI-PROJECT-16059101
  • [Journal Article] Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes.2004

    • Author(s)
      Kobayashi, A., Ohta, T, Yamamoto, M.
    • Journal Title

      Methods Enzymol. 378

      Pages: 1208-1213

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Transgenic rescue of GATA-1-deficient mice with GATA-1 lacking a FOG-1 association site phenocopies patients with X-linked thrombocytopenia.2004

    • Author(s)
      Shimizu, R., Ohneda, K., Engel, J.D., Trainor, C.D., Yamamoto, M.
    • Journal Title

      Blood 103

      Pages: 2560-2567

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] 血色素の分子進化2004

    • Author(s)
      鈴木教郎, 山本雅之
    • Journal Title

      日本医事新報 4177

      Pages: 99-100

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Neurogenin3 delineates the earliest stages of spermatogenesis in the mouse testis.2004

    • Author(s)
      Yoshida, S., Takakura, A., Ohbo, K., Abe, K., Wakabayashi, J., Yamamoto, M., Suda, T., Nabeshima, Y-i.
    • Journal Title

      Dev.Biol 269

      Pages: 447-458

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] 血色素の分子進化2004

    • Author(s)
      鈴木教郎, 山本雅之
    • Journal Title

      日本医事新報 4177

      Pages: 99-100

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] The transcriptional program of antibody class switching involves the repressor Bach2.2004

    • Author(s)
      Muto, A., Tashiro, S., Nakajima, O., Hoshino, H., Takahashi, S., Sakoda, E., Ikebe, D., Yamamoto, M., Igarashi, K.
    • Journal Title

      Nature 429

      Pages: 556-571

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] 転写因子と血液疾患2004

    • Author(s)
      峯岸直子, 山本雅之
    • Journal Title

      臨床検査 48

      Pages: 473-781

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Protection against electrophile and oxidant stress by induction of the phase 2 response : Fate of cysteines of the Keap1 sensor modified by inducers.2004

    • Author(s)
      Wakabayashi, N., Dinkova-Kostova, A.T.Holtzclaw, W.D., Kang, M-L, Kobayashi, A., Yamamoto, M., Kensler, T.W., Talalay, P.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 2040-2045

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2 deficiency causes tooth decolorization due to iron transport disorder in enamel organ.2004

    • Author(s)
      Yanagawa, T., Itoh, K., Uwayama, J., Shibata, Y., Yamaguchi, A., Sato, T., Ishii, T., Yoshida, H., Yamamoto, M.
    • Journal Title

      Genes Cells 9

      Pages: 641-651

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 Mice.2004

    • Author(s)
      Goldring, C.E.P., Kitteringham, N.R., Elsby, R., Randle, L.E., Clement, Y.N., Williams, D.P., McMahon, M., Hayes, J.D., Itoh, K., Yamamoto, M., Park, B.K.
    • Journal Title

      Hepatology 39

      Pages: 1267-1276

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] A GATA-specific inhibitor (K-7174) rescues anemia induced by IL-1b, TNF-a or L-NMMA.2004

    • Author(s)
      Imagawa, S., Nakano, Y., Obara, N., Suzuki, N., Doi, T., Kodama, T., Nagasawa, T., Yamamoto, M.
    • Journal Title

      Blood 104

      Pages: 4300-4307

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Leukemogenesis caused by incapacitated GATA-1 function.2004

    • Author(s)
      Shimizu, R., Kuroha, T., Ohneda, 0., Pan, X., Ohneda, K., Takahashi, S., Philipsen, S., Yamamoto, M.
    • Journal Title

      Mol.Cell.Biol. 24

      Pages: 10814-10825

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Keap1-Nrf2システムによる抗酸化酵素群の統一的発現制御機構2004

    • Author(s)
      細谷朋方, 山本雅之
    • Journal Title

      分子呼吸器病 8

      Pages: 147-150

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] A constitutively active arylhydrocarbon receptor induces growth inhibition of Jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest.2004

    • Author(s)
      Ito, T., Tsukumo, S., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 25204-25210

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] GATA-1ノックダウンマウス2004

    • Author(s)
      清水律子, 山本雅之
    • Journal Title

      Mebio 21

      Pages: 58-62

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Interleukin-6 and tumor necrosis factor-a in patients with obstructive sleep apnea-hypopnea syndrome2004

    • Author(s)
      Imagawa, S., Yamaguchi, Y., Ogawa, K., Obara, N., Suzuki, N., Yamamoto, M., Nagasawa, T
    • Journal Title

      Respiration 71

      Pages: 24-29

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Nrf2-Keap1 defines a physiologically important stress response mechanism.2004

    • Author(s)
      Motohashi, H, Yamamoto, M.
    • Journal Title

      Trends Mal.Med. 10

      Pages: 549-557

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Gene expression profiling of NRF2-mediated protection against oxidative injury.2004

    • Author(s)
      Cho, H-Y., Reddy, S.P., DeBiase, A., Yamamoto, M, Kleeberger, S.R.
    • Journal Title

      Free Rad.Biol.Med. 38

      Pages: 325-343

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Protection against electrophile and oxidant stress by induction of the phase 2 response : Fate of cysteines of the Keap1 sensor modified by inducers.2004

    • Author(s)
      Wakabayashi, N., Dinkova-Kostova, A.T.Holizclaw, W.D., Kang, M-L, Kobayashi, A., Yamamoto, M., Kensler, T.W., Talalay, P.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 101

      Pages: 2040-2045

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Redox-regulated tumover of Nrf2 is determined by at least two separate protein domains the redox sensitive Neh2 degron and the redox-insensitive Neh6 degron.2004

    • Author(s)
      McMahon, M., Thomas, N., Itoh, K., Yamamoto, M., Haves, J.D.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 31556-31567

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] In vivo and in vitro constant expression of GATA-4 in mouse postnatal Sertoli cells.2004

    • Author(s)
      Imai, T., Kawai, Y., Tadokoro, Y., Yamamoto, M., Nishimune, Y., Yomogida, K.
    • Journal Title

      Mol.Cell.Endocrinol. 214

      Pages: 107-115

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Interleukin-6 and tumor necrosis factor-a in patients with obstructive sleep apnea-hypop nea syndrome2004

    • Author(s)
      Imagawa, S., Yamaguchi, Y., Ogawa, K., Obara, N., Suzuki, N., Yamamoto, M., Nagasawa, T.
    • Journal Title

      Respiration 71

      Pages: 24-29

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] 親電子性物質応答の分子機構2004

    • Author(s)
      伊東 健, 山本雅之
    • Journal Title

      生化学 76

      Pages: 339-348

    • NAID

      10012894688

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] GATA転写因子からみる赤血球の発生・分化2004

    • Author(s)
      長野真澄, 山本雅之
    • Journal Title

      実験医学 22

      Pages: 361-366

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] EPR imaging of reducing activity in Nrf2 transcriptional factor-deficient mice.2003

    • Author(s)
      Hirayama, A., Yoh, K., Nagase, S., Ueda, A., Itoh, K., Morito, N., Hirayama, K., Takahashi, S., Yamamoto, M., Koyama, A.
    • Journal Title

      Free Rad.Biol.Med. 34

      Pages: 1236-1242

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003

    • Author(s)
      Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, O., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, T., Tohyama, C., Fujii-Kuriyama, Y., Yamamoto, M.
    • Journal Title

      Proc.Natul.Acad.Sci.USA 100

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Identification of a novel Nrf2-regulated antioxidant response element (ARE) in the mouse NAD(P)H : quinone oxidoreductase 1 gene : reassessment of the ARE consensus sequence.2003

    • Author(s)
      Nioi, P., McMahon, M., Itoh, K., Yamamoto, M., Hayes, J.
    • Journal Title

      Biochem.J. 374

      Pages: 337-348

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway.2003

    • Author(s)
      Kwak, M.K., Wakabayashi, N., Greenlaw, J.L., Yamamoto, M., Kensler, T.W.
    • Journal Title

      Mol.Cell.Biol. 23

      Pages: 8786-8794

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation.2003

    • Author(s)
      Wakabayashi, N., Itoh, K., Wakabayashi, J., Motohashi, H., Noda, S., Takahashi, S., Imakado, S., Kotsuji, T., Otsuka, F., Roop, D.R., Harada, T., Engel, J.D., Yamamoto, M.
    • Journal Title

      Nature Genetics 35

      Pages: 238-245

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse2003

    • Author(s)
      T.Moriguchi, H.Motohashi, T.Hosoya, O.Nakajima, S.Takahashi, S.Ohsako, A.Aoki, N.Nishimura, C.Tohyama, Y.Fujii-Kuriyama, M.Yamamoto
    • Journal Title

      Proc. Natl. Acad. Sci. USA 100

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207100
  • [Journal Article] Antioxidants enhance mammalian proteasome expression through the Keapl-Nrf2 signaling pathway.2003

    • Author(s)
      Kwak, M.K., Wakabayashi, N., Greenlaw, J.L., Yamamoto, M., Kensler, T.W.
    • Journal Title

      Mol.Cell.Biol. 23

      Pages: 8786-8794

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] DNA-adduct formation in lungs, nasal mucosa, and livers of rats exposed to urban roadside air in Kawasaki City, Japan2003

    • Author(s)
      H.Sato, K.T.Suzuki, H.Sone, Y.Yamamoto, J.Kagawa, Y.Aoki
    • Journal Title

      Environmental Research 93

      Pages: 36-44

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14207100
  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor(AHR)-humanized mouse2003

    • Author(s)
      T.Moriguchi, H.Motohashi, T.Hosoya, O.Nakajima, S.Takahashi, S.Ohsako, Y.Aoki, N.Nishimura, C.Tohyama, Y.Fujii-Kuriyama, M.Yamamoto
    • Journal Title

      Proc.Natl.Acad.Sci.USA Vol.100,No.10

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14207100
  • [Journal Article] Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse.2003

    • Author(s)
      Moriguchi, T., Motohashi, H., Hosoya, T., Nakajima, 0., Takahashi, S., Ohsako, S., Aoki, Y., Nishimura, T., Tohyama, C., Fujii-Kuriyama, Y., Yamamoto, M.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 100

      Pages: 5652-5657

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Gene expression of detoxifying enzymes in AhR and Nrf2 compound null mutant mouse.2003

    • Author(s)
      Noda, S., Harada, N., Hida, A., Fujii-Kuriyama, Y., Motohashi, H., Yamamoto, M.
    • Journal Title

      Biochem.Biophys.Res.Commun. 303

      Pages: 105-111

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Expression of the aflatoxin B1-8,9-epoxide-metabolizing murine glutathione S-transferase A3 subunit is regulated by the Nrf2 transcription factor through an antioxidant response element.2003

    • Author(s)
      Jowsey, I.R., Jiang, Q., Itoh, K., Yamamoto, M., Hayes, J.D.
    • Journal Title

      Mol.Pharmacol. 64

      Pages: 1018-1028

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Role of NRF2 in Protein Against Hyperoxic Lung Injury in Mice.2002

    • Author(s)
      Cho, H.Y., Jedlika, A.E., Reddy, S.P.M., Zhang, L.Y., Yamamoto, M., Kensler, T.W., Kleeberger, S.R.
    • Journal Title

      Am.J.Res.Cell Mol.Biol. 26

      Pages: 175-182

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Linkage analysis of susceptibility to hyperoxic lung injury: role of Nrf2 as a candidate gene.2002

    • Author(s)
      Cho, H.Y., Jedlika, A.E., Reddy, S.P.M., Zhang, L.Y., Yamamoto, M., Kensler, T.W., Kleeberger, S.R.
    • Journal Title

      Am.J.Res.Cell Mol.Biol. 26

      Pages: 175-182

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.2002

    • Author(s)
      Thimmulappa, R.K., Mai, K.H., Srisuma, S., Kensler, T.W., Yamamoto, M., Biswal, S.
    • Journal Title

      Cancer Res. 62

      Pages: 5196-5203

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gstal, Gsta2, Gstml, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.2002

    • Author(s)
      Chanas, S.A., Jiang, Q., McMahon, M., McWalter, G.K., McLellan, L.I., Elcombe, C.R., Henderson, C.J., Wolf, C.R., Moffat, G.J., Itoh, K., Yamamoto, M., Hayes, J.D.
    • Journal Title

      Biochem.J. 365

      Pages: 405-416

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.2002

    • Author(s)
      Chanas, S.A., Jiang, Q., McMahon, M., McWalter, G.K., McLellan, L.I., Elcombe, C.R., Henderson, C.J., Wolf, C.R., Moffat, G.J., Itoh, K., Yamamoto, M., Haves, J.D.
    • Journal Title

      Biochem.J. 365

      Pages: 405-416

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] High sensitivity of Nrf2 knockout mice to acetoaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzyme and antioxidant genes.2001

    • Author(s)
      Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T., Yamamoto, M.
    • Journal Title

      Toxicol.Sci. 59

      Pages: 169-177

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.2001

    • Author(s)
      Ramos-Gomez, M., Kwak, M-K., Dolan, P.M., Itoh, K., Yamamoto, M., Talalay, P., Kensler, T.W.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 98

      Pages: 3410-3415

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] High sensi-tivity of Nrf2 knockout mice to acetoaminophen hepato-toxicity associated with decreased expression of ARE- regulated drug metabolizing enzyme and antioxidant genes.2001

    • Author(s)
      Enomoto, A., Itoh, K., Nagayoshi, E., Haruta, J., Kimura, T., O'Connor, T., Harada, T., Yamamoto, M.
    • Journal Title

      Toxicol.Sci. 59

      Pages: 169-177

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Accelerated DNA adducts formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust.2001

    • Author(s)
      Aoki, Y., Sato, H., Nishimura, N., Takahashi, S., Itoh, K., Yamamoto, M.
    • Journal Title

      Toxicol.Appl.Pharmacol. 173

      Pages: 154-160

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13357005
  • [Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf3.1999

    • Author(s)
      Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
    • Journal Title

      J. Biol. Chem. 274

      Pages: 6443-6452

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf31999

    • Author(s)
      Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
    • Journal Title

      J.Biol.Chem. 274

      Pages: 6443-6452

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Differential regulation of mouse coproporphyrinogen oxidase geneexpression in erythroid and non-erythroid cells.1998

    • Author(s)
      Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
    • Journal Title

      Blood 92

      Pages: 3436-3444

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Regulation of NF-E2 activity in erythroleukemia cell differentiation.1998

    • Author(s)
      Nagai, T., Igarashi, K., Akasaka, J., Furuyama, K., Fujita, H., Hayashi, N., Yamamoto, M., Sassa, S.
    • Journal Title

      J. Biol. Chem. 273

      Pages: 5358-5365

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Regulation of NF-E2 activity in erythroleukemia cell differentiation1998

    • Author(s)
      Nagai, T., Igarashi, K., Akasaka, J., Furuyama, K., Fujita, H., Hayashi, N., Yamamoto, M., Sassa, S.
    • Journal Title

      J.Biol.Chem. 273

      Pages: 5358-5365

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Differential regulation of mouse coproporphyrinogen oxidase gene expression in erythroid and non-erythroid cells1998

    • Author(s)
      Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
    • Journal Title

      Blood 92

      Pages: 3436-3444

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Alternative promoters regulate transcription of the mouse GATA-2 gene.1998

    • Author(s)
      Minegishi, N., Ohta, J., Suwabe, N., Nakauchi, H., Ishihara, H., Hayashi, N., Yamamoto, M.
    • Journal Title

      J. Biol. Chem. 273

      Pages: 3625-3634

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Deficient heme and globin synthesis in ES cells lacking the erythroid-specific δ-aminolevulinate synthase gene1998

    • Author(s)
      Harigae, H., Suwabe, N., Weinstock, P.H., Nagai, M., Fujita, H., Yamamoto, M., Sassa, S.
    • Journal Title

      Blood 91

      Pages: 798-805

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Deficient heme and globin synthesis in ES cells lacking the erythroid-specific δ-aminolevulinate synthase gene.1998

    • Author(s)
      Harigae, H., Suwabe, N., Weinstock, P.H., Nagai, M., Fujita, H., Yamamoto, M., Sassa, S.
    • Journal Title

      Blood 91

      Pages: 798-805

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Alternative promoters regulate transcription of the mouse GATA-2 gene1998

    • Author(s)
      Minegishi, N., Ohta, J., Suwabe, N., Nakauchi, H., Ishihara, H., Hayashi, N., Yamamoto, M.
    • Journal Title

      J.Biol.Chem. 273

      Pages: 3625-3634

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10557015
  • [Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.

    • Author(s)
      Toki, T., Katsuoka, F., Kanezaki, R., Xu, G., Kurotaki, H., Sun, J., Kamio, T., Watanabe, S., Tandai, S., Terui, K., Yagihashi, S., Komatsu, N., Igarashi, K, Yamamoto, M, Ito, E.
    • Journal Title

      Blood (印刷中)

    • Data Source
      KAKENHI-PROJECT-15390086
  • [Journal Article] Transgenic expression of Bach1 transcription factor results in megakaryocytic impairment.

    • Author(s)
      Toki, T., Katsuoka, F., Kanezaki, R., Xu, G., Kurotaki, H., Sun, J., Kamio, T., Watanabe, S., Tandai, S., Terui, K., Yagihashi, S., Komatsu, N., Igarashi, K., Yamamoto, M., Ito, E.
    • Journal Title

      Blood (印刷中)

    • Data Source
      KAKENHI-PROJECT-15027201
  • [Journal Article] Amino and carboxyl-terminal transactivation domains of GATA1 coordinate the hematopoietic program

    • Author(s)
      Kaneko H, Kobayashi E, Yamamoto M, Shimizu R.
    • Journal Title

      J Biol Chem in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Patent] 糖尿病の予防または治療剤2012

    • Inventor(s)
      山本雅之、宇留野晃、古澤祐樹
    • Industrial Property Rights Holder
      国立大学法人東北大学, 持田製薬株式会社
    • Industrial Property Number
      2012-072990
    • Filing Date
      2012-03-28
    • Data Source
      KAKENHI-PROJECT-22890014
  • [Patent] Nrf1調節剤のスクリーニング方法2012

    • Inventor(s)
      山本雅之、古澤祐樹
    • Industrial Property Rights Holder
      山本雅之、古澤祐樹
    • Industrial Property Number
      2012-011833
    • Filing Date
      2012-01-24
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Patent] うつ病の予防または治療剤2011

    • Inventor(s)
      山本雅之、村松裕行
    • Industrial Property Rights Holder
      山本雅之、村松裕行
    • Industrial Property Number
      2011-283379
    • Filing Date
      2011-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Patent] Epo欠損GFPtg貧血マウス2011

    • Inventor(s)
      山本雅之、峯岸直子、山寄瞬
    • Industrial Property Rights Holder
      山本雅之、峯岸直子、山寄瞬
    • Industrial Property Number
      2011-083664
    • Filing Date
      2011-04-05
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Regulation and Function of the KEAP1-NRF2 Stress Response System2023

    • Author(s)
      Yamamoto M
    • Organizer
      Cell & Developmental Biology Seminar, University of Michigan Medical School
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] The KEAP1/NRF2 system in health and disease2023

    • Author(s)
      Yamamoto M
    • Organizer
      Annual Meeting of the Society for Free Radical Research Europe
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] Elucidation of molecular basis of oxidative stress response utilizing mouse, human and space biology2022

    • Author(s)
      Yamamoto M
    • Organizer
      Redox Week in Sendai 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] 食道上皮におけるNrf2活性化細胞の周囲細胞の代償的増殖2022

    • Author(s)
      廣瀬亘、田口恵子、山本雅之
    • Organizer
      日本生化学会東北支部第88回例会・シンポジウム
    • Data Source
      KAKENHI-PROJECT-22K19450
  • [Presentation] 細胞競合によるNRF2活性化細胞の排除機構2022

    • Author(s)
      廣瀬亘、堀内真、田口恵子、谷山祐亮、山本雅之、亀井尚
    • Organizer
      第76回日本食道学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K19450
  • [Presentation] The KEAP1-NRF2 System in Cancer Biology and Medicine2022

    • Author(s)
      Yamamoto M
    • Organizer
      The 53rd Korean Academy of Science and Technology (KAST) International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] The KEAP1-NRF2 System in Biology and Medicine2022

    • Author(s)
      Yamamoto M
    • Organizer
      Cancer Seminar for Honorary Doctorate at University of Eastern Finland
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] The KEAP1-NRF2 pathway regulating cellular response against oxidative and electrophilic stresses2022

    • Author(s)
      Yamamoto M
    • Organizer
      Kunio Yagi Lecture on IUBMB-FEBS Congress,
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] Molecular Basis of Oxidative Stress Sensing and Diseases2022

    • Author(s)
      Yamamoto M
    • Organizer
      The 10th Biennial Meeting of Society for Free Radical Research-Asia: New Paradigm for Research on Oxidative Stress & Inflammation.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] Regulation of NRF2-KEAP1 Stress Sensing Mechanisms in the Kidney2022

    • Author(s)
      Yamamoto M
    • Organizer
      Keynote Lecture at the FASEB Science Research Conferences on Polycystic Kidney Disease: Hurdles and Advancesin Molecular Mechanisms and Therapies
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] KEAP1センサー機能の分子基盤の解明2019

    • Author(s)
      山本雅之
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] 酸化ストレス応答の分子メカニズムと病態2019

    • Author(s)
      山本雅之
    • Organizer
      わかもと先進眼科医療研究会特別講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] 酸化ストレス応答の分子メカニズムと病態2019

    • Author(s)
      山本雅之
    • Organizer
      CVMW2019心血管代謝週間
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1-NRF2 制御系と発がん2019

    • Author(s)
      山本雅之
    • Organizer
      第7回がんと代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1-NRF2 regulatory pathway for environmental stress response and renal erythropoietin producing cells2019

    • Author(s)
      Yamamoto M
    • Organizer
      Boehringer Ingelheim
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1センサー機能の分子基盤の解明2019

    • Author(s)
      山本雅之
    • Organizer
      第92回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] 酸化ストレス応答の分子メカニズムと病態2019

    • Author(s)
      山本雅之
    • Organizer
      CVMW2019心血管代謝週間
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] Keap1-Nrf2 Antioxidative stress response system2019

    • Author(s)
      Yamamoto M
    • Organizer
      Paris Redox 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1-NRF2 制御系と発がん2019

    • Author(s)
      山本雅之
    • Organizer
      第7回がんと代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] 宇宙ストレスにおける環境応答型転写因子Nrf2の役割2019

    • Author(s)
      山本雅之
    • Organizer
      JAXA 小動物飼育ミッション 宇宙実験 知見交換会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] Keap1-Nrf2 Antioxidative stress response system2019

    • Author(s)
      Yamamoto M
    • Organizer
      Paris Redox 2019,
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H05649
  • [Presentation] KEAP1-NRF2 System Regulating Cellular Oxidative Stress Response2018

    • Author(s)
      山本雅之
    • Organizer
      Nrf2 Seminar, Faculty of Pharmacy Paris Sud
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] がん微小環境におけるNrf2活性化による腫瘍抑制効果.2018

    • Author(s)
      林真貴子, 久我有祐美, 本橋ほづみ, 鈴木未来子, 山本雅之.
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 貧血による血圧低下と腎エリスロポエチン細胞におけるレニン産生誘導2018

    • Author(s)
      宮内健一郎, 伊藤貞嘉, 山本雅之, 鈴木教郎
    • Organizer
      第27回腎とエリスロポエチン研究会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Specific cell activation of Nrf2 in SCD mice can modify the evolution of the pathology.2018

    • Author(s)
      Nadine Keleku-Lukwete, Harit Panda, Mikiko Suzuki, Fumiki Katsuoka, Akihito Otsuki, Daisuke Saigusa, Ritsumi Saitou, Akira Uruno, Masayuki Yamamoto.
    • Organizer
      第91回日本生化学大会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 転写因子NRF2-sMaf二量体結合配列の多様性の評価.2018

    • Author(s)
      大槻晃史、勝岡史城、山本雅之.
    • Organizer
      第41回分子生物学会大会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] KEAP1-NRF2 システムとがんの治療2018

    • Author(s)
      山本雅之
    • Organizer
      秋田大学病院がんプロ講演
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1-NRF2 Regulatory Pathway for Environmental Stress Response2018

    • Author(s)
      山本雅之
    • Organizer
      Environmental Health and Toxicology meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Misexpression of EVI1 and GATA2 provokes leukemia associated with high number of megakaryocytes2018

    • Author(s)
      Mikiko Suzuki, Ayaka Yamaoka, Saori Katayama, Masayuki Yamamoto
    • Organizer
      The 21st Hemoglobin Switching Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] 腎エリスロポエチン産生細胞 「REP細胞」の細胞株樹立と腎臓線維化機構の解析2018

    • Author(s)
      佐藤浩司, 平野育生, 関根弘樹, 宮内健一郎, 加藤幸一郎, 伊藤貞嘉, 山本雅之, 鈴木教郎
    • Organizer
      日本生化学会東北支部 第84回例会・シンポジウム
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] The Keap1-Nrf2 Stress Response System in Cancer Biology and Medicine2018

    • Author(s)
      山本雅之
    • Organizer
      Cancer Colloquium on NRF2
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] KEAP1-NRF2 System Regulating Oxidative Stress Response2018

    • Author(s)
      山本雅之
    • Organizer
      ISN FRONTIERS
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2-MafGテザードヘテロ二量体分子は、小Maf群因子欠失細胞においてNrf2標的遺伝子の一群を特異的に活性化する.2018

    • Author(s)
      勝岡史城、大槻晃史、高橋瑞恵、山本雅之.
    • Organizer
      第91回日本生化学大会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] KEAP1-NRF2 Regulatory Pathway for Environmental Stress Response2018

    • Author(s)
      Yamamoto M
    • Organizer
      Environmental Health and Toxicology meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] GATA2ハプロ不全はEVI1誘導性白血病の発症を促進する2018

    • Author(s)
      片山紗乙莉, 鈴木未来子, 山岡彩香, Nadine Keleku-Lukwete, 勝岡史城, 大槻晃史, 呉繁夫, Jemes Douglas Engel, 山本雅之
    • Organizer
      第14回血液学若手研究者勉強会(麒麟塾)
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] 3番染色体転座・逆位による高血小板型白血病モデルマウスの樹立と解析2018

    • Author(s)
      山岡彩香, 鈴木未来子, 片山紗乙莉, 山本雅之
    • Organizer
      日本生化学会東北支部第84回例会
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] Roles KEAP1-NRF2 System Plays in Neurosciences and Diseases2018

    • Author(s)
      Yamamoto M
    • Organizer
      Stanford University symposium
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] がんの生物学と医学におけるKEAP1-NRF2制御系の役割2018

    • Author(s)
      山本雅之
    • Organizer
      第77回日本癌学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] がんの生物学と医学におけるKEAP1-NRF2制御系の役割2018

    • Author(s)
      山本雅之
    • Organizer
      第77回日本癌学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 and its future2018

    • Author(s)
      Yamamoto M
    • Organizer
      EUROTOX2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] GATA transcription factors: a quarter century of discoveries2018

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      IUBMB Focused Meeting on GATA Transcription Factors
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] KEAP1-NRF2 System Regulating Oxidative Stress Response2018

    • Author(s)
      Yamamoto M
    • Organizer
      NHRI-ToMMo conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] Roles KEAP1-NRF2 System Plays in Neurosciences and Diseases2018

    • Author(s)
      山本雅之
    • Organizer
      Stanford University symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] システイン反応性Nrf2誘導剤に対する応答を欠失したKeap1変異体の創出2018

    • Author(s)
      鈴木隆史、村松亜紀、斎藤良太, 磯達朗、山本雅之
    • Organizer
      第91回日本生化学大会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Structural and functional analyses of oxidative stress response by Keap1-Nrf2 system.2018

    • Author(s)
      Seizo Koshiba, Tatsuro Iso, Jin Inoue, Aki Muramatsu, Takafumi Suzuki, Takanori Kigawa and Masayuki Yamamoto.
    • Organizer
      28th ICMRBS
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] GATA transcription factors: a quarter century of discoveries2018

    • Author(s)
      山本雅之
    • Organizer
      IUBMB Focused Meeting on GATA Transcription Factoers
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1酸化ストレスセンサーの機能解析2018

    • Author(s)
      村松亜紀、鈴木隆史、斎藤良太, 磯達朗、須田博美、守田匡伸、山本雅之
    • Organizer
      第91回日本生化学大会
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] The Keap1-Nrf2 System for Understanding of Diseases and Drug Development2018

    • Author(s)
      Yamamoto M
    • Organizer
      World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] The Keap1-Nrf2 System for Understanding of Diseases and Drug Development2018

    • Author(s)
      山本雅之
    • Organizer
      京都World Congress of Basic and Clinical Pharmacology (WCP2018)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] KEAP1-NRF2 System Regulating Cellular Oxidative Stress Response2018

    • Author(s)
      Yamamoto M
    • Organizer
      Nrf2 Seminar, Faculty of Pharmacy Paris Sud
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] KEAP1-NRF2システムと病態・創薬2018

    • Author(s)
      山本雅之
    • Organizer
      バルドキソロン全国研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] Keap1-Nrf2制御系の構造生物学的アプローチと病態2018

    • Author(s)
      山本雅之
    • Organizer
      第42回蛋白質と酸素の構造と機能に関する九州シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19417
  • [Presentation] Nrf2 and its future2018

    • Author(s)
      山本雅之
    • Organizer
      EUROTOX2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1-Nrf2制御系の構造生物学的アプローチと病態2018

    • Author(s)
      山本雅之
    • Organizer
      第42回蛋白質と酸素の構造と機能に関する九州シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 腎エリスロポエチン産生細胞 (REP細胞) 由来の細胞株は細胞自律性TGFβ発現により筋線維芽細胞の形質を有する2018

    • Author(s)
      佐藤浩司, 平野育生, 関根弘樹, 宮内健一郎, 加藤幸一郎, 伊藤貞嘉, 山本雅之, 鈴木教郎
    • Organizer
      第91回日本生化学会大会シンポジウム
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 3 番染色体転座・逆位による白血病発症機構2017

    • Author(s)
      鈴木未来子, 山岡彩香, 片山紗乙莉, 山本雅之
    • Organizer
      第22回造血器腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] KEAP1-NRF2システムによる環境ストレス応答制御機構と病態2017

    • Author(s)
      山本雅之
    • Organizer
      第54回日本臨床分子医学会
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 3番染色体転座・逆位を伴う白血病におけるGATA2遺伝子発現減少の貢献2017

    • Author(s)
      鈴木未来子, 山岡彩香, 片山紗乙莉, 山本雅之
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] 酸素恒常性維持における赤血球造血系の役割とその破綻による病態への影響2017

    • Author(s)
      鈴木教郎, 潘 小青, 東條 裕, 平野育生, 山崎瞬, 関根弘樹, 山本雅之, 宮田敏男
    • Organizer
      第57回日本臨床化学会年次学術集会 教育講演
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] KEAP1-NRF2制御系のエピジェネティクス制御2017

    • Author(s)
      山本雅之
    • Organizer
      日本毒性学会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] マウス皮膚における紫外線DNA損傷量と誘発突然変異頻度の定量的関係の解析2017

    • Author(s)
      池畑広伸,森俊雄,山本雅之
    • Organizer
      日本放射線影響学会第60回大会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017

    • Author(s)
      鈴木隆史, 関詩織, 長沼絵里子, 高橋信行, 佐藤博, 山本雅之
    • Organizer
      第60回日本腎臓学会学術会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] エリスロポエチン産生細胞と病態2017

    • Author(s)
      山本雅之
    • Organizer
      新潟透析医学会学術集会ランチョンセミナー
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] The KEAP1-NRF2 Stress Response System in Biology and Medicine2017

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Annual Meeting of Korean Society of Molecular and Cellular Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 Improves Leptin and Insulin Resistance Provoked by SelenocysteinetRNA Knockout in Hypothakamus2017

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Se 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 尿細管発生期における転写因子Nrf2の恒常的活性化は腎性尿崩症を引き起こす2017

    • Author(s)
      鈴木隆史, 関詩織, 長沼絵理子, 高橋信行,佐藤博, 山本雅之
    • Organizer
      第40回生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] 環境ストレス応答機構の発見のその生理的・病理的意義の解明2017

    • Author(s)
      山本雅之
    • Organizer
      ConBio2017 柿内三郎賞受賞講演
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 骨髄球系細胞における転写因子Nrf2活性化がエラスターゼ誘導性肺気腫の形成を阻害する2017

    • Author(s)
      佐藤慶, 鈴木隆史, 長沼絵理子, 杉浦久敏, 一ノ瀬正和, 山本雅之
    • Organizer
      第40回生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] 酸化ストレス応答におけるKeap1の構造・相互作用解析2017

    • Author(s)
      井上仁, 村松亜紀, 鈴木隆史, 磯達朗, 小柴生造, 山本雅之
    • Organizer
      第56回NMR討論会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Molecular basis of Keap1-Nrf2 system and Cancer2017

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Better Cancer Therapy from Redox Biology, the Banbury Center Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1-Nrf2系による酸化ストレス防御機構2017

    • Author(s)
      鈴木隆史, 山本雅之
    • Organizer
      第7回日本分子状水素医学生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] マウス皮膚に対する広帯域および狭帯域UVBのゲノム毒性の比較2017

    • Author(s)
      池畑広伸, 森俊雄, 山本雅之
    • Organizer
      第39回日本光医学・光生物学会
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Keap1-Nrf2システムによる酸化ストレス応答機構2017

    • Author(s)
      鈴木隆史, 山本雅之
    • Organizer
      第17回日本蛋白質学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] GATA2 enhancer-driven EVI1 overexpression induces progenitor expansion and myeloid lineage skewing.2016

    • Author(s)
      Mikiko Suzuki, Saori Katayama, James Douglas Engel, Masayuki Yamamoto.
    • Organizer
      The 20th Annual Conference Hemoglobin Switching
    • Place of Presentation
      Asilomar, California
    • Year and Date
      2016-09-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] イソチアゾール骨格を有する新規Nrf2活性化剤の創製2016

    • Author(s)
      斉藤文彦、神野智之、中原基、水野貴志、竹内勝俊、荒井ゆかり、千代田幸治、川本雅毅、前田能崇、東知佳、林真貴子、津田直人、河路淳子、村井武彦、内田一也、神谷昌嗣、那波弘康、中尾一成、古迫正司、宇留野晃、山本雅之
    • Organizer
      第34回メディシナルケミストリーシンポジウム
    • Place of Presentation
      つくば(つくば国際会議場)
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] A novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2016

    • Author(s)
      Higashi C, Hayashi M, Tsuda N, Kawaji A, Nakao K, Satoh F, Nakamura M, Furusako S, Saito R, Suzuki T, Uruno A, Yamamoto M.
    • Organizer
      The 32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
    • Place of Presentation
      ロンドン(イギリス)
    • Year and Date
      2016-09-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] p62:Nrf2 double knockout mice develop steatohepatitis through the serum endotoxin overload.2016

    • Author(s)
      Kentaro Akiyama, Eiji Warabi, Kosuke Okada, Syunnichi Ariizumi, Masakazu Yamamoto, Junnichi Shoda.
    • Organizer
      25th Conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の転写阻害2016

    • Author(s)
      小林枝里、鈴木隆史、舟山亮、長嶋剛史、中山啓子、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] The Keap1-Nrf2 system and lung diseases2016

    • Author(s)
      山本雅之
    • Organizer
      日本毒性学会学術年会
    • Place of Presentation
      ウインクあいち, 名古屋
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] The effect of female hormones on NAFLD in p62 knockout mice.2016

    • Author(s)
      Miho Ikeuchi, Eiji Warabi, Tsugumi Nagaoka, Syunichi Ariizumi, Masakazu Yamamoto, Junichi Shoda.
    • Organizer
      25th Conference of the Asian Pacific Association for the Study of the Liver
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Presentation] 生体の酸化・親電子性物質ストレス応答の分子基盤2016

    • Author(s)
      山本雅之
    • Organizer
      第46回日本腎臓学会東部学術大会
    • Place of Presentation
      神戸ポートピアホテル, 神戸
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] A novel Nrf2 inducer TFM-735 ameliorates experimental autoimmune encephalomyelitis in mice.2016

    • Author(s)
      Higashi C, Hayashi M, Tsuda N, Kawaji A, Nakao K, Satoh F, Nakamura M, Furusako S, Saito R, Suzuki T, Uruno A, Yamamoto M.&#160;
    • Organizer
      32nd Congress of the European Committee for Treatment and Research in Multiple Sclerosis
    • Place of Presentation
      London (United Kingdom)
    • Year and Date
      2016-09-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] The effect of female hormones on NAFLD in p62 knockout mice.2016

    • Author(s)
      Miho Ikeuchi, Eiji Warabi, Tsugumi Nagaoka, Syunichi Ariizumi, Masakazu Yamamoto, Junichi Shoda.
    • Organizer
      25th Conference of the Asian Pacific Association for the Study of the Live
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15488
  • [Presentation] GATA2 haploinsufficiency accelerates EVI1-driven leukemogenesis in an inv(3)(q21q26) mouse model.2016

    • Author(s)
      Mikiko Suzuki, Saori Katayama, Shigeo Kure, James Douglas Engel, Masayuki Yamamoto.
    • Organizer
      The 41st Naito Conference on “Cancer Heterogeneity and Plasticity: Relevance to Therapeutic Resistance”
    • Place of Presentation
      シャトレーゼ ガトーキングダム サッポロ, 札幌
    • Year and Date
      2016-07-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] ダビガトランによる剥離性食道炎を伴った食道表在癌の1例2016

    • Author(s)
      野中 遥奈, 田島 大樹, 廣瀬 優, 山浦 正道, 菅沼 大輔, 佐藤 雅志, 内田 優一, 山田 武史, 山本 祥之, 長谷川 直之, 石毛 和紀, 金子 剛, 鈴木 英雄, 奈良坂 俊明, 福田 邦明, 安部井 誠人, 兵頭 一之介, 溝上 裕士
    • Organizer
      第103回日本消化器内視鏡学会関東支部会
    • Place of Presentation
      シェーンバッハ・サボー(東京都・千代田区)
    • Year and Date
      2016-12-17
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Presentation] Keap1センサーシステイン残基による多様なストレス感知機構2016

    • Author(s)
      鈴木隆史、山本雅之
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Keap1センサーシステイン残基による多様なストレス感知機構2016

    • Author(s)
      鈴木隆史、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Renal Erythropoietin Producing Cells for Anemia and Fibrosis2016

    • Author(s)
      Yamamoto M.
    • Organizer
      International Congress on Nutrition and Metabolism in Renal Disease
    • Place of Presentation
      Okinawa Convention Center, Okinawa
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1-Nrf2制御システムと疾患2016

    • Author(s)
      山本雅之
    • Organizer
      25回日本CellDeath学会
    • Place of Presentation
      大井町きゅりあん, 東京
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2活性化は骨形成低下を引き起こす2016

    • Author(s)
      吉田瑛紀、鈴木隆史、長沼絵理子、小林枝里、守田匡伸、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Nrf2によるグリコーゲン分枝鎖酵素遺伝子発現制御機構の解明2016

    • Author(s)
      相川享、宇留野晃、柳下陽子、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response.2016

    • Author(s)
      Suzuki T, Saito R, Hiramoto K, Asami S, Naganuma E, Suda H, Iso T, Yamamoto H, Morita M, Baird L, Furusawa Y, Negishi T, Ichinose M, Yamamoto M.
    • Organizer
      The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-05-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] ダビガトランによる剥離性食道炎を伴った食道表在癌の1例2016

    • Author(s)
      野中 遥奈, 田島 大樹, 廣瀬 優, 山浦 正道, 菅沼 大輔, 佐藤 雅志, 内田 優一, 山田 武史, 山本 祥之, 長谷川 直之, 石毛 和紀, 金子 剛, 鈴木 英雄, 奈良坂 俊明, 福田 邦明, 安部井 誠人, 兵頭 一之介, 溝上 裕士
    • Organizer
      第103回日本消化器内視鏡学会関東支部会
    • Place of Presentation
      シェーンバッハ・サボー(東京都・千代田区)
    • Year and Date
      2016-12-17
    • Data Source
      KAKENHI-PROJECT-15K15488
  • [Presentation] エリスロポエチン産生の制御機構2016

    • Author(s)
      山本雅之
    • Organizer
      27th Forum in DOJIN
    • Place of Presentation
      熊本ホテルキャッスル, 熊本
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 糖尿病におけるKeap1-Nrf2系の役割2016

    • Author(s)
      宇留野晃、柳下陽子、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] Impact of Keap1-Nrf2 system for toxicology and drug development2016

    • Author(s)
      Yamamoto M.
    • Organizer
      International ISSX Meeting
    • Place of Presentation
      Busan, Korea
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Molecular Basis of the Keap1-Nrf2 System Regulating Environmental Stress Response2016

    • Author(s)
      山本雅之
    • Organizer
      日本研究皮膚科学会 第41回年次学術大会
    • Place of Presentation
      仙台国際センター, 仙台
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Air pollution activates Aryl hydrocarbon receptor in murine epidermis, leading to Atopic dermatitis-like pathologies.2016

    • Author(s)
      Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, and Masayuki Yamamoto.
    • Organizer
      The 41st Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-12-09
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Molecular Basis of Oxidative and Environmental Stress response2016

    • Author(s)
      Yamamoto M
    • Organizer
      CDB Seminar
    • Place of Presentation
      Michigan, USA
    • Year and Date
      2016-04-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 紫外線ゲノム毒性に対するKEAP1-NRF2系の皮膚防護能2016

    • Author(s)
      池畑広伸、山田亮太郎、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Amelioration of inflammation and tissue damage in sickle cell disease by Nrf2 activation2016

    • Author(s)
      Yamamoto M.
    • Organizer
      20th Hb Switching Conference
    • Place of Presentation
      Seattle, USA
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Air polluteon induces Atopic dermatitiss-like pathologyes via Aryl hydrocarbon receptor2016

    • Author(s)
      日高高徳、小林枝里、鈴木隆史、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] The NRF2 Antioxidant Response System in Biology and Medicine2016

    • Author(s)
      Yamamoto M
    • Organizer
      Karolinska Seminar
    • Place of Presentation
      Stockholm, Sweden
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] The origin and fate of renal Epo-producing cells in health and disease2016

    • Author(s)
      Yamamoto M.
    • Organizer
      the 6th International NCCR Kidney.CH Symposium
    • Place of Presentation
      Zurich, Switzerland
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1の反応性システイン残基による多様なストレス感知機構2016

    • Author(s)
      鈴木隆史、山本雅之
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2016-08-30
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] p62:Nrf2 double knockout mice develop steatohepatitis through the serum endotoxin overload.2016

    • Author(s)
      Kentaro Akiyama, Eiji Warabi, Kosuke Okada, Syunnichi Ariizumi, Masakazu Yamamoto, Junnichi Shoda.
    • Organizer
      25th Conference of the Asian Pacific Association for the Study of the Live
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2016-02-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15488
  • [Presentation] EVI1遺伝子高発現による白血病発症機構の解明2016

    • Author(s)
      片山紗乙莉, 鈴木未来子, 呉繁夫, 山本雅之
    • Organizer
      第20回造血器腫瘍研究会
    • Place of Presentation
      千葉(かずさアークアカデミアホール)
    • Year and Date
      2016-02-12
    • Data Source
      KAKENHI-PROJECT-26670463
  • [Presentation] 腎臓におけるエリスロポエチン遺伝子発現制御機構の解明2016

    • Author(s)
      平野育生, 鈴木教郎, 清水律子, 山本雅之
    • Organizer
      第24回腎とエリスロポエチン研究会
    • Place of Presentation
      品川プリンスホテル 東京
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Air pollution activates Aryl hydrocarbon receptor of un-differentiated keratinocytes, leading to Atopic dermatitis-like pathologiesn.2016

    • Author(s)
      Takanori Hidaka, Eri H Kobayashi, Takafumi Suzuki, Masayuki Yamamoto.
    • Organizer
      46th Annual Meeting of the European Society for Dermatological Research. the Technical University of Munich
    • Place of Presentation
      Munich (Germany)
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Characterization of three major cysteine sensors of Keap1 in stress response.2016

    • Author(s)
      T. Suzuki, R. Saito, K. Hiramoto, S. Asami, E. Naganuma, H. Suda, T. Iso, H. Yamamoto, M. Morita, L. Baird, Y. Furusawa, T. Negishi, M. Ichinose, M. Yamamoto
    • Organizer
      The 9th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2016-05-20
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Keap1の反応性システイン残基による多様なストレス感知機構2016

    • Author(s)
      鈴木隆史、山本雅之
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Year and Date
      2016-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Identification and Evaluation of Isothiazole-Based Novel Nrf2 inducers2016

    • Author(s)
      Saitoh F, Kamino T, Nakahara M, Mizuno T, Takeuchi K, Arai Y, Chiyoda K, Kawamoto M, Maeda Y, Higashi C, Hayashi M, Tsuda N, Kawaji A, Murai T, Uchida K, Kamiya M, Naba H, Nakao K, Furusako S, Uruno A, Yamamoto M.
    • Organizer
      The 35th National Medicinal Chemistry Symposium
    • Place of Presentation
      シカゴ(アメリカ合衆国)
    • Year and Date
      2016-06-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] エリスロポエチンによる赤血球の代謝制御2016

    • Author(s)
      福田愛菜, 加藤幸一郎, 河野あかり, 齋藤さかえ, 山本雅之, 鈴木教郎
    • Organizer
      第89回日本生化学会大会
    • Place of Presentation
      仙台国際センター, 仙台
    • Year and Date
      2016-09-25
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] EPO欠乏性貧血マウスにおけるC.E.R.A.の造血作用機序2016

    • Author(s)
      鈴木教郎, 山本雅之
    • Organizer
      第24回腎とエリスロポエチン研究会
    • Place of Presentation
      品川プリンスホテル 東京
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Chromosomal rearrangements between 3q21 and 3q26 induce leukemogenesis by misdirecting both EVI1 and GATA2 genes.2016

    • Author(s)
      Mikiko Suzuki, Saori Katayama, Hiromi Yamazaki, James Douglas Engel, Masayuki Yamamoto.
    • Organizer
      第78回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜, 横浜
    • Year and Date
      2016-10-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] ストレスセンサーKeap1のシステイン変異体ノックインマウスの機能解析2015

    • Author(s)
      浅見颯一郎、斎藤良太、平本圭一郎、鈴木隆史、山本雅之
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] EVI1遺伝子高発現白血病における白血病発症機構2015

    • Author(s)
      片山紗乙莉, 鈴木未来子, 呉繁夫, 山本雅之
    • Organizer
      日本生化学会東北支部第81回例会
    • Place of Presentation
      仙台(東北大学さくらホール)
    • Year and Date
      2015-05-09
    • Data Source
      KAKENHI-PROJECT-26670463
  • [Presentation] 分子構造に基づく転写因子Nuclear factor (erythroid-derived 2)-like 2(Nrf2)の抗酸化剤応答配列認識機構の解析2015

    • Author(s)
      鈴木香絵、椎名政昭、浜田恵輔、石川涼平、金井達哉、豊後泰子、岡田千佳子、馬場しほ、鈴木隆史、太田力、山本雅之、緒方一博
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Nrf2 regulates glucose metabolism-related genes2015

    • Author(s)
      Yagishita Y, Uruno A, Katsuoka F, Funayama R, Nakayama K, Kensler TW, Yamamoto M.
    • Organizer
      27th Annyal UPCI Scientific Retreat
    • Place of Presentation
      Pittsburgh (アメリカ合衆国)
    • Year and Date
      2015-06-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] ストレスセンサーKeap1のシステイン変異体ノックインマウスの機能解析2015

    • Author(s)
      浅見颯一郞、斎藤良太、平本圭一郎、鈴木隆史、山本雅之
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] 骨格筋におけるNrf2のグリコーゲン代謝制御機構2015

    • Author(s)
      宇留野晃、柳下陽子、山本雅之
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] ヒトIL6 遺伝子モニターマウスを用いたin vivoイメージングによる炎症状態解析システムの開発とその利用2015

    • Author(s)
      林 真貴子, 高井 淳, 于 磊, 本橋 ほづみ, 森口 尚, 山本 雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] マウス皮膚におけるUVCゲノム毒性の解析2015

    • Author(s)
      池畑広伸、森俊雄、山本雅之
    • Organizer
      第37回日本光医学・光生物学会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎市)
    • Year and Date
      2015-07-17
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] 造血因子エリスロポエチンの細胞系列特異的・低酸素誘導的発現制御機構2015

    • Author(s)
      鈴木教郎, 関根弘樹, 相馬友和, 東條裕, 袮津昌広, 宮田敏男, 山本雅之.
    • Organizer
      第13回がんとハイポキシア研究会
    • Place of Presentation
      国立遺伝学研究所(三島市)
    • Year and Date
      2015-06-05
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Hypoxia signaling cascade for in vivo erythropoietin production.2015

    • Author(s)
      Norio Suzuki, Hiroki Sekine, Tomokazu Souma, Yutaka Tojo, Masahiro Nezu, Toshio Miyata, Masayuki Yamamoto.
    • Organizer
      Keystone Symposium on Hypoxia
    • Place of Presentation
      Dublin, Ireland
    • Year and Date
      2015-05-12
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2欠損マウスにおけるアセトアミノフェン誘発性肝障害の機序検討~ミトコンドリアFusion/Fissionへ及ぼす影響~2015

    • Author(s)
      森脇さや香、後藤志麻、宮脇出、出口二郎、船橋斉、鈴木隆史、山本雅之
    • Organizer
      第42回日本毒性学会学術年会
    • Place of Presentation
      金沢(石川県音楽堂、金沢市アートホール、ホテル日航金沢)
    • Year and Date
      2015-06-29
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Keap1-Nrf2 System: Potential Role in Prevension of Sickle Cell Disease and Inflammation2015

    • Author(s)
      Nadine Keleku-Lukwete, Mikiko Suzuki, Akihito Otsuki, Kouhei Tsuchida, Saori Katayama, Makiko Hayashi, Eriko Naganuma, Takashi Moriguchi, Osamu Tanabe, James Douglas Engel, and Masayuki Yamamoto.
    • Organizer
      57th ASH Annual Meeting
    • Place of Presentation
      Orland (USA)
    • Year and Date
      2015-12-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 regulates glucose metabolism-related genes.2015

    • Author(s)
      Yagishita Y, Uruno A, Katsuoka F, Funayama R, Nakayama K, Yamamoto M.
    • Organizer
      The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Cambridge (Robinson College)
    • Year and Date
      2015-01-07
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] GATA因子阻害は非エリスロポエチン産生細胞からの異所性エリスロポエチン発現を誘GATA因子阻害は非エリスロポエチン産生細胞からの異所性エリスロポエチン発現を誘導する2015

    • Author(s)
      金子寛、佐谷秀行、山本雅之、清水律子
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015

    • Author(s)
      斎藤良太、平本圭一郎、浅見颯一郞、鈴木隆史、山本雅之
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] NRF2-MED16を介した抗酸化遺伝子群の転写活性化機構.2015

    • Author(s)
      岡崎慶斗, 関根弘樹, 鈴木教郎, 加藤恭丈, 五十嵐和彦, 伊藤光宏, 本橋ほづみ, 山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2はPten欠失による脂肪肝炎から肝臓がんの移行を促進する2015

    • Author(s)
      田口恵子, 一戸理沙, 山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015

    • Author(s)
      斎藤良太、平本圭一郎、浅見颯一郎、鈴木隆史、山本雅之
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Keap1-Nrf2システムによるTrsp欠失マウス膵β細胞および視床下部の酸化ストレス防御機構2015

    • Author(s)
      柳下陽子、福富俊明、宇留野晃、山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸 (神戸ポートアイランド)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] 骨格筋におけるNrf2のグリコーゲン代謝制御機構2015

    • Author(s)
      宇留野晃、柳下陽子、山本雅之
    • Organizer
      第88回日本生化学会大会合同大会(BMB2015)
    • Place of Presentation
      神戸 (神戸ポートアイランド)
    • Year and Date
      2015-12-03
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] ストレス応答におけるNrf2, Keap1, Cul3の細胞内分子挙動の解析2015

    • Author(s)
      磯達朗, 鈴木隆史, 山本雅之
    • Organizer
      第81回日本生化学会東北支部例会
    • Place of Presentation
      仙台(東北大学さくらホール)
    • Year and Date
      2015-05-09
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] エリスロポエチン遺伝子の腎特異的転写制御領域の解析と腎性貧血モデルマウスの樹立2015

    • Author(s)
      平野育生, 鈴木教郎, 祢津昌広, 関根弘樹, 相馬友和, 峯岸直子, 清水律子, 山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] A stress-responsive transcriptional factor NRF2 activates hematopoietic stem cells.2015

    • Author(s)
      Shohei Murakami, Masayuki Yamamoto, Hozumi Motohashi.
    • Organizer
      57th ASH Annual Meeting
    • Place of Presentation
      Orland (USA)
    • Year and Date
      2015-12-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] EVI1遺伝子高発現白血病における白血病発症機構2015

    • Author(s)
      片山紗乙莉, 鈴木未来子, 呉繁夫, 山本雅之.
    • Organizer
      日本生化学会東北支部第81回例会
    • Place of Presentation
      東北大学さくらホール(宮城県、仙台市)
    • Year and Date
      2015-05-09
    • Data Source
      KAKENHI-PROJECT-15H02507
  • [Presentation] ストレスセンサーKeap1のシステイン変異体ノックインマウスの機能解析2015

    • Author(s)
      浅見颯一郎、斎藤良太、平本圭一郎、鈴木隆史、山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 regulates glucose metabolism-related genes.2015

    • Author(s)
      Yagishita Y, Uruno A, Katsuoka F, Funayama R, Nakayama K, Yamamoto M
    • Organizer
      27th Annyal UPCI Scientific Retreat
    • Place of Presentation
      Pittsburgh. USA
    • Year and Date
      2015-06-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1-Nrf2システムによるTrsp欠失マウス膵β細胞および視床下部の酸化ストレス防御機構2015

    • Author(s)
      柳下陽子、福富俊明、宇留野晃、山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2欠失ラットはアフラトキシンB1による肝毒性に対して脆弱である2015

    • Author(s)
      田口恵子, 高久美咲, Thomas W. Kensler, 山本雅之.
    • Organizer
      第42回日本毒性学会学術年会
    • Place of Presentation
      石川県立音楽堂(金沢市)
    • Year and Date
      2015-06-29
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 regulates glycogen metabolism in skeletal muscle.2015

    • Author(s)
      Uruno A, Yagishita Y, Yamamoto M.
    • Organizer
      The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Cambridge (Robinson College)
    • Year and Date
      2015-01-07
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] Keap1-Nrf2システムによるTrsp欠失マウス膵β細胞および視床下部の酸化ストレス防御機構2015

    • Author(s)
      柳下陽子、福富俊明、宇留野晃、山本雅之
    • Organizer
      第38回日本分子生物学会年会 第88回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド(神戸)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] 新規変異体創出によるストレスセンサーKeap1のシステイン残基の機能解明2015

    • Author(s)
      斎藤良太、平本圭一郎、浅見颯一郎、鈴木隆史、山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Nrf2 regulates glucose metabolism-related genes.2015

    • Author(s)
      Yoko Yagishita, Akira Uruno, Fumiki Katsuoka, Thomas Kensler, Masayuki Yamamoto
    • Organizer
      27th Annual UPCI Scientific Retreat
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2015-06-18
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] 骨格筋におけるNrf2のグリコーゲン代謝制御機構2015

    • Author(s)
      宇留野晃、柳下陽子、山本雅之
    • Organizer
      第38回分子生物学会/第88回日本生化学会大会合同大会(BMB 2015)
    • Place of Presentation
      神戸国際会議場(神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] In vivo analysis of UVC-induced mutation in mouse skin: dose-dependent induction kinetics and mutation spectrum.2015

    • Author(s)
      H. Ikehata, T. Mori, M. Yamamoto
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都国際会議場(京都市)
    • Year and Date
      2015-05-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H02815
  • [Presentation] Aryl hydrocarbon receptor activation in keratinocyte leads to atopic dermatitis-like lesion via artemin induction2015

    • Author(s)
      Takanori Hidaka, Eisaku Ogawa, Eri H Kobayashi, Takafumi Suzuki, Taku Fujimura, Setsuya Aiba, Ryuhri Okuyama, Masayuki Yamamoto.
    • Organizer
      45th Annual Meeting of the European Society for Dermatological Research
    • Place of Presentation
      Rotterdam (Netherland)
    • Year and Date
      2015-09-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 環境ストレスへの生体応答の分子基盤2014

    • Author(s)
      山本雅之
    • Organizer
      第56回日本先天代謝異常学会総会
    • Place of Presentation
      江陽グランドホテル(仙台市)
    • Year and Date
      2014-11-13
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Molecular Basis of the Keap1-Nrf2 System Regulating Environmental Stress Response2014

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Nobel Conference
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2014-10-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] エリスロポエチン産生細胞とエリスロポエチン遺伝子の発現制御機構2014

    • Author(s)
      山本雅之
    • Organizer
      日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2014-11-02
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 9.山本雅之、エリスロポエチン産生細胞と腎疾患、2014

    • Author(s)
      山本雅之
    • Organizer
      第45回新潟腎カンファランス
    • Place of Presentation
      新潟大学(新潟)
    • Year and Date
      2014-09-25
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] エリスロポエチン産生細胞とエリスロポエチン遺伝子の発現制御機構2014

    • Author(s)
      山本雅之
    • Organizer
      日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2014-11-02
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Keap1-Nrf2制御系と発がん2014

    • Author(s)
      山本雅之
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2014-09-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Erythropoietin production in neural and neural crest cells during primitive erythropoiesis2014

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      19th Hemoglobin Switching Conference
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2014-09-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] エリスロポエチン産生細胞と腎疾患2014

    • Author(s)
      山本雅之
    • Organizer
      第45回新潟腎カンファランス
    • Place of Presentation
      新潟大学(新潟市)
    • Year and Date
      2014-09-25
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] 腎臓EPO産生細胞を巡る最近の話題2014

    • Author(s)
      山本雅之
    • Organizer
      第59回日本透析医学会学術集会・総会
    • Place of Presentation
      ポートピアホテル(神戸)
    • Year and Date
      2014-06-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Keap1-Nrf2システムと肝臓・糖尿病2014

    • Author(s)
      山本雅之
    • Organizer
      第1回肝臓と糖尿病・代謝研究会
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2014-07-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 酸素と医学2014

    • Author(s)
      山本雅之
    • Organizer
      レドックスシンポジウム 酸素生物学の誕生
    • Place of Presentation
      名古屋大学(名古屋市)
    • Year and Date
      2014-10-11
    • Invited
    • Data Source
      KAKENHI-PLANNED-26111002
  • [Presentation] Erythropoietin production in neural and neural crest cells during primitive erythropoiesis2014

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      19th Hemoglobin Switching Conference
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2014-09-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 染色体転座・逆位におけるEVI1遺伝子活性化および白血病発症機構の解析2014

    • Author(s)
      鈴木未来子、山崎博未、大槻晃史、清水律子、Emery H. Bresnick、James Douglas Engel、山本雅之
    • Organizer
      第10回血液学若手研究者勉強会(麒麟塾)
    • Place of Presentation
      コクヨホール、東京
    • Year and Date
      2014-07-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670463
  • [Presentation] 転写因子Nrf2の遺伝子発現量の重要性2014

    • Author(s)
      鈴木隆史、柴田龍弘、高屋快、本橋ほづみ、山本雅之
    • Organizer
      日本生化学会東北支部 第80回例会
    • Place of Presentation
      秋田、アキタパークホテル
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Nrf2による糖尿病の発症抑制作用2014

    • Author(s)
      宇留野晃、古澤祐樹、柳下陽子、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] Nrf2による酸化ストレス糖尿病モデルマウスの膵β細胞保護2014

    • Author(s)
      柳下陽子、宇留野晃、福富俊明、菅原明、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] Keap1-Nrf2システムは糖尿病発症を抑制する2014

    • Author(s)
      宇留野晃、古澤祐樹、柳下陽子、福富俊明、山本雅之
    • Organizer
      第80回日本生化学会東北支部例会
    • Place of Presentation
      秋田(アキタパークホテル)
    • Year and Date
      2014-05-10
    • Data Source
      KAKENHI-PROJECT-26460383
  • [Presentation] 酸素と医学2014

    • Author(s)
      山本雅之
    • Organizer
      レドックスシンポジウム
    • Place of Presentation
      名古屋大学(名古屋)
    • Year and Date
      2014-10-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression2013

    • Author(s)
      山㟢博未,鈴木未来子,加藤幸一郎,大槻晃史,清水律子, James Douglas Engel,山本雅之
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場神戸(ポスター発表,ポスター番号; 3P0852)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 環境応答の分子基盤と病態2013

    • Author(s)
      山本雅之
    • Organizer
      第6回システム疾患生命科学による先端医療技術開発シンポジウム
    • Place of Presentation
      東京大学山上会館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Molecular Mechanisms of the Keap1-Nrf2 Pathway in Stress Response and Cancer Evolution2013

    • Author(s)
      Yamamoto M
    • Organizer
      Special lecture, University of Pittsburgh Cancer Institute
    • Place of Presentation
      Pittsburgh, PA, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] GATA転写因子群の機能異常と白血病2013

    • Author(s)
      山本雅之
    • Organizer
      Tsukuba Hematologic Disease Seminar
    • Place of Presentation
      筑波大学
    • Year and Date
      2013-03-29
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子GATA1による胎児型グロビン遺伝子発現制御機構の解析2013

    • Author(s)
      濱中悠賀、鈴木未来子、山㟢博未、清水律子、James Douglas Engel、山本雅之
    • Organizer
      転写研究会 若手ワークショップ@鬼怒川
    • Place of Presentation
      日光市
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 赤血球系転写因子の発現制御とエピジェネティクス機構2013

    • Author(s)
      山本雅之
    • Organizer
      第7回日本エピジェネティクス研究会年会
    • Place of Presentation
      奈良県新公会堂
    • Year and Date
      2013-05-31
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] GATA1アミノ末端側亜鉛フィンガーによるDNA結合親和性調節機構が赤血球分化に果たす役割2013

    • Author(s)
      長谷川敦史,金子寛,山本雅之,清水律子
    • Organizer
      日本生化学会東北支部第79回例会・シンポジウム
    • Place of Presentation
      東北大学さくらホール,仙台(口頭発表,要旨集p26, No. C-1)
    • Year and Date
      2013-05-11
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 3q21q26症候群におけるEVI1転写活性化と白血病発症の分子機構2013

    • Author(s)
      山㟢博未,鈴木未来子,加藤幸一郎,清水律子, James Douglas Engel,山本雅之
    • Organizer
      日本生化学会東北支部第79回例会
    • Place of Presentation
      東北大学さくらホール仙台(ポスター発表,要旨集; p45)
    • Year and Date
      2013-05-11
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] Epo遺伝子転写調節領域の探索2013

    • Author(s)
      平野育生,鈴木教郎,峯岸直子,山本雅之,清水律子
    • Organizer
      第11回がんとハイポキシア研究会
    • Place of Presentation
      東北大学片平さくらホール,仙台)(口演・ポスター)
    • Year and Date
      2013-12-13
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 大槻シス配列に依存したGATA1-DNA結合親和性修飾機構の生理機能解析2013

    • Author(s)
      長谷川敦史,清水律子,金子寛,山本雅之
    • Organizer
      東北大学大学院医学系研究科第6回リトリート大学院生研究発表会
    • Place of Presentation
      東北大学さくらホール仙台(ポスター発表,要旨集p70, No. P-5-E)
    • Year and Date
      2013-01-19
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] トランスジェニックマウスを利用したエリスロポエチン遺伝子エンハンサーの探索2013

    • Author(s)
      平野育生、鈴木教郎、山㟢瞬、峯岸直子、山本雅之、清水律子
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場神戸(ポスター発表, 1P-0195)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] Functional expansion of Nrf2 under the sustained activation of proliferative signals2013

    • Author(s)
      Hozumi Motohashi, Tsuyoshi Higa, Keiko Taguchi, Yoichiro Mitsuishi, Masayuki Yamamoto
    • Organizer
      Keystone Symposium
    • Place of Presentation
      Santa Fe, NM, USA
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Reciprocal activation between Nrf2 and a proliferative signaling in liver2013

    • Author(s)
      Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      1st International Symposium on Protein Modifications in Pathogenic Dysregulation of Signaling
    • Place of Presentation
      University of Tokyo
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 白血病逆位モデルマウスを用いたEVI1高発現白血病発症機構の解析2013

    • Author(s)
      鈴木未来子、山㟢博未、加藤幸一郎、清水律子、James Douglas Engel、山本雅之
    • Organizer
      第17回造血器腫瘍研究会
    • Place of Presentation
      宮崎
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 赤血球分化に関わる転写因子GATA1によるROS制御機構の解明2013

    • Author(s)
      大槻晃史,金子寛,清水律子,山本雅之
    • Organizer
      東北大学大学院医学系研究科第6回リトリート大学院生研究発表会
    • Place of Presentation
      東北大学さくらホール仙台(ポスター発表,要旨集p 73)
    • Year and Date
      2013-01-19
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] A remote GATA2 hematopoietic enhancer drives leukemogenesis in inv(3)(q21;q26) by activating EVI1 expression.2013

    • Author(s)
      山崎博未, 鈴木未来子, 加藤幸一郎, 大槻晃史, 清水律子, James Douglas Engel, 山本雅之
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子による血小板の分化と機能発現の制御メカニズム血小板2013

    • Author(s)
      山本雅之
    • Organizer
      巨核球学術講演会
    • Place of Presentation
      盛岡グランドホテル
    • Year and Date
      2013-09-28
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] Erythroid commitment of hematopoietic stem cells2013

    • Author(s)
      Yamamoto M
    • Organizer
      The 75^<th> Annual Meeting, Japanese Society of Hematology
    • Place of Presentation
      さっぽろ芸文館
    • Year and Date
      2013-10-11
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 3q21q26白血病染色体転座・逆位モデルマウスを用いたEVI1遺伝子転写活性化機構の解析2013

    • Author(s)
      鈴木未来子,山㟢博未,加藤幸一郎,清水律子, James Douglas Engel,山本雅之
    • Organizer
      転写研究会&転写サイクル&転写代謝システム若手ワークショップ@鬼怒川
    • Place of Presentation
      ホテル鬼怒川御苑鬼怒川(口頭/ポスター発表,要旨集; p22)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 染色体逆位モデルマウスを用いたEVI1高発現白血病発症機構の解析2013

    • Author(s)
      鈴木未来子,山㟢博未,加藤幸一郎,清水律子, James Douglas Engel,山本雅之
    • Organizer
      第17回造血器腫瘍研究会
    • Place of Presentation
      シーガイア・コンベンションセンター宮崎(口頭発表)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子GATA1による胎児型グロビン遺伝子発現制御機構の解明2013

    • Author(s)
      濱中悠賀,鈴木未来子,山㟢博未,清水律子,山本雅之
    • Organizer
      東北大学大学院医学系研究科第6回リトリート大学院生研究発表会
    • Place of Presentation
      東北大学片平さくらホール,仙台(ポスター発表,要旨集p 58)
    • Year and Date
      2013-01-19
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] トランスジェニックマウスを利用したエリスロポエチン遺伝子エンハンサーの探索2013

    • Author(s)
      平野育生, 鈴木教郎, 山崎瞬, 峯岸直子, 山本雅之, 清水律子
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子GATA1による胎児型グロビン遺伝子発現制御機構の解明2013

    • Author(s)
      濱中悠賀,鈴木未来子,山㟢博未,清水律子,山本雅之
    • Organizer
      転写研究会&転写サイクル&転写代謝システム若手ワークショップ@鬼怒川
    • Place of Presentation
      ホテル鬼怒川御苑鬼怒川(ポスター発表,要旨集; p53)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子GATA2の尿細管特異的欠損マウスは尿濃縮障害を呈する2013

    • Author(s)
      Yu Lei 、森口 尚、相馬友和、高井淳、山本雅之
    • Organizer
      第23回バゾプレシン研究会
    • Place of Presentation
      慶應義塾大学病院
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 肝毒性物質による肝肥大における転写因子Nrf2の役割2013

    • Author(s)
      田口恵子、本橋ほづみ、伊藤暢、田中稔、宮島篤、山本雅之
    • Organizer
      フォーラム2013:衛生薬学・環境トキシコロジー
    • Place of Presentation
      九州大学
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 動物モデルによる環境応答研究の展開2013

    • Author(s)
      山本雅之
    • Organizer
      第29回日本毒性病理学会学術集会
    • Place of Presentation
      つくば
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 特定のヘテロ型Keap1変異体は野性型Keap1に対してドミナントネガティブに働く2012

    • Author(s)
      鈴木隆史, Jonathan Maher, 山本雅之
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Keap1-Nrf2 System: A Master Regulator of Redox Signaling2012

    • Author(s)
      Yamamoto M
    • Organizer
      The 33rd NAITO conference
    • Place of Presentation
      Sapporo
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] シス配列多様性に依存したGATA1-DNA結合親和性修飾機構の生理機能解析2012

    • Author(s)
      長谷川敦史,清水律子,金子寛,黒河博文,山本雅之
    • Organizer
      BIA Symposium 2012 (GE Healthcare)
    • Place of Presentation
      明治記念館,東京(ポスター発表, A-3)
    • Year and Date
      2012-07-20
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] マウス遺伝学と環境応答研究2012

    • Author(s)
      山本雅之
    • Organizer
      筑波大学生命科学動物資源センター10周年記念シンポジウム
    • Place of Presentation
      つくば(招待講演)
    • Year and Date
      2012-02-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Hypoxia-inducible and tissue-specific erythropoietin gene regulation2012

    • Author(s)
      Yamamoto M.
    • Organizer
      Keystone Symposium : Advances in Hypoxic Signaling
    • Place of Presentation
      バンフ(カナダ)
    • Year and Date
      2012-02-02
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Amino- and Carboxyl-terminal transactivation domains of GATA1 coordinate the hematopoietic program2012

    • Author(s)
      Kaneko H, Kobayashi E, Shimizu R, Yamamoto M
    • Organizer
      The 18th Conference on Hemoglobin Switching
    • Place of Presentation
      Asiloma, USA
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] Hypoxia-inducible and tissue-specific erythropoietin gene regulation2012

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Keystone Symposia ; Advances in Hypoxic Signaling
    • Place of Presentation
      アルバータ、カナダ(招待講演)
    • Year and Date
      2012-02-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境ストレス応答の分子基盤2012

    • Author(s)
      山本雅之
    • Organizer
      信州大学セミナー
    • Place of Presentation
      信州大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 環境ストレス応答の分子基盤と病態2012

    • Author(s)
      山本雅之
    • Organizer
      都医学研セミナー
    • Place of Presentation
      東京
    • Year and Date
      2012-02-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2 ノックアウトマウスはウレタン肺発癌に抵抗性を示し,Nrf2 欠損癌結節はNude マウスへの著しい生着不全を示す2012

    • Author(s)
      佐藤大希,森口尚,海老名雅仁,山本雅之
    • Organizer
      第52回日本呼吸器学会学術総会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 肝特異的Nrf1欠損マウスの作出と肝における脂質代謝経路の解析2012

    • Author(s)
      辻田忠志,Vivian Mullin,Jullian L Griffin,山本雅之,John D Hayes
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] シス配列多様性に依存したGATA1-DNA結合親和性修飾機構の生理機能解析2012

    • Author(s)
      長谷川敦史,清水律子,金子寛,黒河博文,山本雅之
    • Organizer
      平成24年度「転写代謝システム」領域班会議
    • Place of Presentation
      つくばグランドホテル,つくば(ポスター発表, P-18)
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 転写因子Nrf2欠損はKras経路の抑制と肺発生関連遺伝子の発現低下を介してウレタン誘導性肺発癌悪性化を阻害する2012

    • Author(s)
      佐藤 大希,森口 尚,海老名 雅仁,貫和 敏博,山本 雅之
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 転写因子NF-E2 p45による血小板機能調節遺伝子の転写活性化2012

    • Author(s)
      藤田理恵、辻本昌理子、藤井聡、皿井明倫、油谷浩幸、本橋ほづみ、山本雅之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 酸化・低酸素ストレスと腎疾患2012

    • Author(s)
      山本雅之
    • Organizer
      第42回日本腎臓学会西部学術大会
    • Place of Presentation
      沖縄
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Keap1-Nrf2系機能の分子および遺伝学基盤2012

    • Author(s)
      山本雅之
    • Organizer
      日本遺伝学会84回大会
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2ノックアウトマウスはウレタン投与による肺癌形成が阻害され、形成されたNrf2欠損癌結節はNudeマウスへの著しい生着不全を示す2012

    • Author(s)
      佐藤大希、森口尚、守田匡伸、海老名雅仁、山本雅之
    • Organizer
      平成23年度「個体レベルでのがん研究支援活動」ワークショップ
    • Place of Presentation
      滋賀
    • Year and Date
      2012-01-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1-Nrf2システム機能の分子構造基盤2012

    • Author(s)
      山本雅之
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 環境応答破綻と炎症の慢性化2012

    • Author(s)
      山本雅之
    • Organizer
      千里ライフサイエンスセミナー
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in metabolic reprogramming2012

    • Author(s)
      Mitsuishi Y, Taguchi K, Aburatani H, Yamamoto M, Motohashi H
    • Organizer
      Keystone Symposium on Cancer and Metabolism
    • Place of Presentation
      アルバータ、カナダ
    • Year and Date
      2012-02-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1-Nrf2システムとPten-PI3K-Aktシグナルのクロストークは肝臓における細胞増殖と分化を制御する2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      GCOE冬の合宿2012
    • Place of Presentation
      秋保
    • Year and Date
      2012-02-04
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular Basis Connecting Environmental Stress to Gene Expression Regulation2012

    • Author(s)
      山本雅之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 酸化・低酸素ストレスと腎臓2012

    • Author(s)
      山本雅之
    • Organizer
      第34回腎臓セミナー
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2-sMaf2量体のDNA結合配列指向性と転写制御機構のゲノムワイド解析2012

    • Author(s)
      弘津陽介、勝岡史城、長嶋剛史、西田有一郎、舟山亮、中山啓子、山本雅之
    • Organizer
      新学術領域研究「転写代謝システム」と転写研究会若手ワークショップ
    • Place of Presentation
      湯河原
    • Year and Date
      2012-02-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] DNA binding diversity achieved through the interaction of GATA1 N-finger and GATA motif is important for embryonic erythropoiesis.2012

    • Author(s)
      Hasegawa A, Shimizu R, Kurokawa H, Yamamoto M
    • Organizer
      54th ASH Annual Meeting and Exposition
    • Place of Presentation
      Georgia World Congress Center, Atlanta, USA
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 4NQO誘発舌がんにおけるKeap1-Nrf2系の役割2012

    • Author(s)
      大越明、鈴木隆史、小林俊光、山本雅之
    • Organizer
      第147回日本耳鼻咽喉科学会宮城県地方部会学術講演会
    • Place of Presentation
      仙台
    • Year and Date
      2012-03-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] In vivo validation of the multiple sensing mechanism of the Keap1-Nrf2 system2012

    • Author(s)
      Takafumi Suzuki, Kai Takaya, Hozumi Motohashi, Thomas W Kensler and Masayuki Yamamoto
    • Organizer
      The 33rd NAITO conference
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] DNA binding diversity achieved through the interaction of GATA1 N-finger and GATA motif is important for embryonic erythropoiesis2012

    • Author(s)
      Hasegawa A, Shimizu R, Kurokawa H, Yamamoto M
    • Organizer
      54^<th> ASH Annual Meeting and Exposition, Georgia World Congress Center
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 腎臓におけるエリスロポエチン産生REP細胞と線維化2012

    • Author(s)
      山本雅之
    • Organizer
      第21回 腎とエリスロポエチン研究会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] シス配列多様性に依存したGATA1-DNA結合親和性修飾機構の生理機能解析2012

    • Author(s)
      長谷川 敦史, 清水 律子, 金子 寛, 黒河 博文, 山本 雅之
    • Organizer
      平成24年度「転写代謝システム」領域班会議
    • Place of Presentation
      つくばグランドホテル
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 酸化・低酸素ストレスと腎臓2012

    • Author(s)
      山本雅之
    • Organizer
      腎臓内科セミナー
    • Place of Presentation
      東京医科歯科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 生体防御システムを支える転写因子Nrf2-MafGのゲノムワイド解析2012

    • Author(s)
      弘津陽介、勝岡史城、西田有一郎、舟山亮、中山啓子、山本雅之
    • Organizer
      NM-GCOE第5回リトリード
    • Place of Presentation
      仙台
    • Year and Date
      2012-01-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Amino- and Carboxyl-terminal transactivation domains of GATA1 coordinate the hematopoietic program2012

    • Author(s)
      Kaneko H, Eri Kobayashi, Shimizu R, Yamamoto M
    • Organizer
      The 18th Conference on Hemoglobin Switching, Asiloma Conference Grounds
    • Place of Presentation
      CA, USA
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] 酸化ストレス応答の分子基盤2012

    • Author(s)
      山本雅之
    • Organizer
      神戸先端医療センターセミナー
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 環境応答の分子基盤2012

    • Author(s)
      山本雅之
    • Organizer
      大阪大学GCOEセミナー
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Keap1-Nrf2 system and hematopoiesis2012

    • Author(s)
      Yamamoto M
    • Organizer
      18th Hemoglobin Switching Meeting
    • Place of Presentation
      Asilomar, CA, USA
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2-小Maf転写因子のゲノムワイド解析による遺伝子発現制御システムの解明2012

    • Author(s)
      弘津陽介, 勝岡史城, 舟山 亮, 長嶋 剛史, 西田 有一郎, 中山 啓子, James Douglas Engel, 山本雅之
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2酸化ストレス応答系による病態制御2012

    • Author(s)
      山本雅之
    • Organizer
      第53回神経学会学術大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] がん細胞における酸化ストレス応答機構の役割と代謝リプログラミングへの貢献2012

    • Author(s)
      光石陽一郎、田口恵子、山本雅之、本橋ほづみ
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 環境応答の分子基盤2012

    • Author(s)
      山本雅之
    • Organizer
      ERATO研究成果報告会
    • Place of Presentation
      埼玉
    • Year and Date
      2012-01-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 癌悪性化に関わるNrf2-DLG癌変異のKeap1結合阻害の構造的基盤2012

    • Author(s)
      福富俊明,黒河博文,内堀雄介,佐藤雅紀,磯達朗,和泉喜子,里見進,山本雅之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Development of an inducible liver-specific Nrf1 knockout mouse that has allowed a metabolomic analysis of the development of non-alcoholic steato hepatitis (NASH) in adult animals2012

    • Author(s)
      Tadayuki Tsujita, Vivian Mullin, Jullian L Griffin, Masayuki Yamamoto and John D Hayes
    • Organizer
      The 33rd NAITO conference
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Crosstalk between Keap1-Nrf2 system and Pten-PI3K-Akt signaling regulates cellular proliferation and differentiation2012

    • Author(s)
      Taguchi K, Motohashi H, and Yamamoto M
    • Organizer
      The 33rd NAITO conference
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Molecular Basis of Keap1-Nrf2 System Function2012

    • Author(s)
      Yamamoto M
    • Organizer
      Oxygen Club California Conference
    • Place of Presentation
      Alba, Italy
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 肝臓における2つのNrf2活性制御機構と胆管形成2012

    • Author(s)
      田口恵子、本橋ほづみ、山本雅之
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Keap1-Nrf2 system for maintenance of redox homeostasis.2012

    • Author(s)
      Taguchi K, Fujikawa N, Motohashi H, and Yamamoto M
    • Organizer
      The 6th International Congress of Asian Society of Toxicology (ASIATOX-VI)
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 造血幹細胞・前駆細胞におけるKeap1-Nrf2制御系の役割の解明2012

    • Author(s)
      村上昌平、本橋ほづみ、山本雅之
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 転写因子Nrf2欠損はウレタン誘導性肺発癌を減少させ、Nrf2欠損癌組織は免疫不全マウスで著しい生着不全と増殖能低下をきたす2011

    • Author(s)
      佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011

    • Author(s)
      Takafumi Suzuki, Jonathan Maher, Masayuki Yamamoto
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes, Island, Greece
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] Keap1による多様なストレス感知機構2011

    • Author(s)
      高屋快、鈴木隆史、本橋ほづみ、山本雅之
    • Organizer
      新学術領域研究「活性酸素シグナル」第6回班会議
    • Place of Presentation
      東京
    • Year and Date
      2011-05-14
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 腎臓Erythropoietin産生細胞の単離と遺伝子発現様式の解析2011

    • Author(s)
      潘小青、鈴木教郎、平野育生、山嵜瞬、峯岸直子、山本雅之
    • Organizer
      新学術領域「細胞運命制御」総括班主催「若手の会」
    • Place of Presentation
      軽井沢
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] CNC因子と小Maf因子のヘテロ二量体による生体防御遺伝子の発現制御の意義2011

    • Author(s)
      勝岡史城、山嵜博未、山本雅之
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 慢性腎臓病における繊維化と腎性貧血を担う細胞の同定およびその制御法の開発2011

    • Author(s)
      高瀬昌幸、浅田礼光、中村仁、小口綾貴子、浅田美咲子、鈴木教郎、山村研一、名越慈人、芝田晋介、Tata Rao Nagaswara、Hans Fehling Joerg、深津敦司、峯岸直子、北徹、木村剛、岡野栄之、山本雅之、柳田素子
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 動脈硬化+高脂肪食誘発肝炎における転写因子Nrf2の役割2011

    • Author(s)
      岡田浩介, 杉本浩一, 正田純一, 堀江正樹, 蕨栄治, 後藤直宏, 石井哲郎, 山本雅之
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] インチンコウ湯は転写因子Nrf2を活性化し,生体の抗酸化ストレス応答機構を賦活化する2011

    • Author(s)
      岡田浩介, 正田純一, 山本雅浩
    • Organizer
      第97回日本消化器病学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] Analysis of the Role of Nrf2-Keapl System in Hematopoietic Stem Cell.2011

    • Author(s)
      Shohei Murakami, Hozumi Motohashi, Masayuki Yamamoto.
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium2010/5th International Symposium on GATA factors.
    • Place of Presentation
      仙台
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Keap1-Nrf2システムとAktシグナルの相互作用と肝疾患2011

    • Author(s)
      田口恵子, 本橋ほづみ, 山本雅之
    • Organizer
      新学術領域研究「修飾シグナル病」領域推進会議
    • Place of Presentation
      東京
    • Year and Date
      2011-07-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Transcription factor Nrf2 drives the pentosew phosphate pathway and glutamine consumption proliferating cells2011

    • Author(s)
      Nanako Fujikawa, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes, Island, Greece
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] エリスロポエチン欠損マウスの部分レスキューによる遺伝性超貧血マウスの樹立2011

    • Author(s)
      山嵜瞬, 峯岸直子, 鈴木教郎, 山本雅之
    • Organizer
      新学術領域「細胞運命制御」総括班主催「若手の会」
    • Place of Presentation
      軽井沢
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011

    • Author(s)
      Suzuki T, Maher J, Yamamoto M.
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] 転写因子Nrf2はペントースリン酸経路とグルタミン代謝を制御して細胞増殖に貢献する2011

    • Author(s)
      光石陽一郎、田口恵子、油谷浩幸、貫和敏博、本橋ほづみ、山本雅之
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 含セレン蛋白質とNrf2による酸化ストレス防御機構の脳発達時期における役割2011

    • Author(s)
      大越明、鈴木隆史、西島維知子、山本雅之
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 膵β細胞におけるKeap1-Nrf2システムの役割2011

    • Author(s)
      宇留野晃、柳下陽子、菅原明、山本雅之
    • Organizer
      第77回日本生化学会東北支部会例会
    • Place of Presentation
      仙台
    • Year and Date
      2011-07-23
    • Data Source
      KAKENHI-PROJECT-22890014
  • [Presentation] 転写因子Nrf2の活性制御タンパク質Keap1の分解と合成2011

    • Author(s)
      田口恵子, 藤川奈々子、本橋ほづみ, 山本雅之
    • Organizer
      フォーラム2011:衛生薬学・環境トキシコロジー
    • Place of Presentation
      金沢
    • Year and Date
      2011-10-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] レドックス恒常性維持に重要なKeap1分解機構の解明2011

    • Author(s)
      藤川奈々子、田口恵子、本橋ほづみ、山本雅之
    • Organizer
      平成23年度がん若手ワークショップ
    • Place of Presentation
      蓼科
    • Year and Date
      2011-08-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Functional Roles of NF-E2 p45 in the Regulation of Platelet Activity.2011

    • Author(s)
      Rie Fujita, Mariko Takayama-Tsujimoto, Hozumi Motohashi, Masayuki Yamamoto.
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium2010/5th International Symposium on GATA factors.
    • Place of Presentation
      仙台
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Yoichiro Mitsuishi, Keiko Taguchi, Masayuki Yamamoto, Hozumi Motohashi
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Embryonic lethality and fetal liver hypoplasia in mice lacking all three small Maf proteins.2011

    • Author(s)
      Fumiki Katsuoka, Hiromi Yamazaki, Hozumi Motohashi, James Douglas Engel, Masayuki Yamamoto.
    • Organizer
      9th Japanese Biochemical Society(JBS)Bio-Frontier Symposium2010/5th International Symposium on GATA factors.
    • Place of Presentation
      仙台
    • Year and Date
      2011-11-17
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] HIF-HRE系によるエリスロポエチン遺伝子の低酸素誘導的・組織特異的転写制御機構2011

    • Author(s)
      鈴木教郎、潘小青、山本雅之
    • Organizer
      第9回がんとハイポキシア研究会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子NF-E2 p45による血小板機能制御メカニズムの解明2011

    • Author(s)
      藤田理恵、辻本昌理子、油谷浩幸、本橋ほづみ、山本雅之
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] マウス遺伝学解析に基盤とするKeap1-Nrf2システムの解明2011

    • Author(s)
      山本雅之、鈴木隆史、田口恵子、本橋ほづみ
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋(招待講演)
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 胆管がん診断へ向けた新たなコンビネーション診断系の確立2011

    • Author(s)
      松田厚志、久野敦、松崎英樹、川本徹、鹿内俊秀、中沼安二、山本雅一、大河内信弘、池原譲、正田純一、平林淳、成松久
    • Organizer
      第31回日本分子腫瘍マーカー研究会
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] Keap1による多様なストレス感知機構の実証2011

    • Author(s)
      高屋快、鈴木隆史、山本雅之
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis Discovery on Target2011

    • Author(s)
      Mitsuishi Y, Taguchi K, Motohashi H, Yamamoto M.
    • Organizer
      Cancer Cell Metabolism as Drug Target
    • Place of Presentation
      Park Plaza Hotel & Towers, Boston, MA, USA
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] Nrf2 activates the pentose phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Mitsuishi Y, Taguchi K, Yamamoto M, Motohashi H.
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes, Island, Greece
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] Transcription factor Nrf2 drives the pentosew phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Fujikawa N, Taguchi K, Motohashi H, Yamamoto M.
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes, Island, Greece
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Yoichiro Mitsuishi, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Discovery on Target, Cancer Cell Metabolism as Drug Target
    • Place of Presentation
      Park Plaza Hotel & Towers, Boston, MA, USA
    • Data Source
      KAKENHI-PROJECT-23659167
  • [Presentation] Transcription factor Nrf2 drives the pentose phosphate pathway and glutamine consumption in proliferating cells2011

    • Author(s)
      Yoichiro Mitsuishi, Keiko Taguchi, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      Discovery on Target ; Cancer Cell Metabolism as Drug Target
    • Place of Presentation
      Boston, USA
    • Year and Date
      2011-11-02
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 糖鎖プロファイリング解析による肝内胆管癌の新規糖蛋白質マーカーの開発2011

    • Author(s)
      正田純一, 川本徹, 中沼安二, 山本雅一, 大河内信弘, 松田厚志, 久野敦, 池原譲, 平林淳, 成松久
    • Organizer
      第47回日本肝臓総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] 胎仔期神経細胞、神経堤細胞によるエリスロポエチン産生2011

    • Author(s)
      平野育生, 鈴木教郎, 潘小青, 山嵜瞬, 峯岸直子, 山本雅之
    • Organizer
      新学術領域「細胞運命制御」総括班主催「若手の会」
    • Place of Presentation
      軽井沢
    • Year and Date
      2011-09-23
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo2011

    • Author(s)
      Takafumi Suzuki, Jonathan Maher, Masayuki Yamamoto
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1 degradation by autophagy for the maintenance of redox homeostasis2011

    • Author(s)
      Fujikawa N, Taguchi K, Motohashi H, Yamamoto M
    • Organizer
      16th World Congress on Advances in Oncology and 14th International Symposium on Molecular Medicine
    • Place of Presentation
      Rhodes Island, Greece
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      分子生物学会第10回春季シンポジウム
    • Place of Presentation
      松島
    • Year and Date
      2010-06-08
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸素と医学2010

    • Author(s)
      山本雅之
    • Organizer
      創生応用医学研究会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Erythropoietin from neural and neural crest cells support primitive erythropoiesis2010

    • Author(s)
      Hirano I, Suzuki N, Pan X, Minegishi N, Yamamoto M
    • Organizer
      9th Japanese Biochemical Society Bio-frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Regulation of platelet reactivity by transcription factor NF-E2 p45 in megakaryocytes2010

    • Author(s)
      藤田理恵、高山昌理子、本橋ほづみ、山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Nrf2-Keap1 System and Respiratory Diseases2010

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide
    • Place of Presentation
      京都
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf2はヒト肺線癌細胞株A549でosteopontinの発現を増加させる2010

    • Author(s)
      光石陽一郎、本橋ほづみ、貫和敏博、山本雅之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice2010

    • Author(s)
      Okada K, Sugimoto H, Shoda J, Warabi E, Ishige K, Ueda T, Taguchi K, Yanagawa T, Nakahara A, Hyodo I, Ishii T, Yamamoto M
    • Organizer
      The 2nd International Forum
    • Place of Presentation
      Niigata, Japan
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] 転写因子Nrf2は宿主肺における癌転移抑制因子である2010

    • Author(s)
      佐藤大希、田口恵子、森口尚、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第50回日本呼吸器学会学術総会
    • Place of Presentation
      湯沢
    • Year and Date
      2010-04-23
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Regulation of platelet reactivity by transcription factor NF-E2 p45 in megakaryocytes2010

    • Author(s)
      藤田理恵、高山昌理子、本橋ほづみ、山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keapl-Nrf2 system and cancer.2010

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Tuesday Special Seminar, Cancer Research Institute of seonl National University
    • Place of Presentation
      韓国、ソウル
    • Year and Date
      2010-06-01
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] 生体のストレス応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      日本抗加齢医学会研修便新用講習会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-05
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] 生体のストレス応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      日本抗加齢医学会研修/更新用講習会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-05
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Analysis of the Role of Nrf2-Keap1 System in Hematopoietic Stem Cell2010

    • Author(s)
      Shohei Murakami, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 成獣における誘導的エリスロポエチン遺伝子破壊の造血に与える影響2010

    • Author(s)
      山嵜瞬、峯岸直子、鈴木教郎、小原直、潘小青、平野育生、寺社下浩一、本田紅里穂、山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf1とNrf2の中枢神経系における機能的差異の検証2010

    • Author(s)
      弘津陽介, 勝岡史城, 小林聡, 山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 宿主におけるNrf2欠損はMDSCs細胞に著明な酸化ストレスの蓄積を誘導し、肺癌転移に対して有利な微小環境を創造する2010

    • Author(s)
      佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] 発癌性物質や酸化ストレスに応答する生体防御系センサーの構造基盤2010

    • Author(s)
      黒河博文、本橋ほづみ、佐藤主税、山本雅之
    • Organizer
      ターゲットタンパク研究プログラム平成22年度成果発表会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] エリスロポエチン産生細胞(Erythropoietin Producing Cells)2010

    • Author(s)
      山本雅之
    • Organizer
      第74回日本皮膚科学会学術大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸素と医学2010

    • Author(s)
      山本雅之
    • Organizer
      創生応用医学研究会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Stress response of megakaryocytes alters inherent reactivity of platelets.2010

    • Author(s)
      Hozumi Motohashi, Rie Fujita, Hironori Satoh, Hiroyuki Aburatani, Masayuki Yamamoto.
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Nrf2-Keapl System and Respiratory Diseases.2010

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 6th International Conference on the Biology, Chemistry, and Therapeutic Applications of Nitric Oxide.
    • Place of Presentation
      京都
    • Year and Date
      2010-06-14
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Cytoplasmic and nuclear degradation mechanisms regulate biological function of the transcription factor Nrf12010

    • Author(s)
      森田智子, 土谷佳樹, 金美姫, 家村俊一郎, 突出貴子, 夏目徹, 山本雅之, 小林聡
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Cytoplasmic and nuclear degradation mechanisms regulate biological function of the transcription factor Nrf12010

    • Author(s)
      森田智子, 土谷佳樹, 金美姫, 家村俊一郎, 突出貴子, 夏目徹, 山本雅之, 小林聡
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 胆嚢発癌とその癌進展に果たすアラキドン酸代謝活性化の役割: Cyclooxygenase-2(COX-2),プロスタグランジンE合成酵素(PGES),プロスタグランジンE受容体(EP)の発現に着目して2010

    • Author(s)
      川本徹, 山本雅一, 正田純一
    • Organizer
      第14回日本肝臓学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] エリスロポエチンの産生細胞と発現制御2010

    • Author(s)
      山本雅之
    • Organizer
      北陸エリスロポエチンフォーラム
    • Place of Presentation
      金沢
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 動脈硬化+高脂肪食誘発脂肪性肝炎における転写因子Nrf2の役割2010

    • Author(s)
      杉本浩一, 岡田浩介, 正田純一, 蕨栄治, 石井哲郎, 山本雅之
    • Organizer
      第14回肝臓学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Lineage Development2010

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly VP, Yamamoto M
    • Organizer
      9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
    • Place of Presentation
      京都
    • Year and Date
      2010-05-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Embryonic lethality and fetal liver hypoplasia in mice lacking all three small Maf proteins2010

    • Author(s)
      Fumiki Katsuoka, Hiromi Yamazaki, Hozumi Motohashi, James Douglas Engel, Masayuki Yamamoto
    • Organizer
      9th Japanese Biochemical Society (JBS) Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Deletion of selenocysteine tRNA gene results in compensatory gene induction of cytoprotective enzymes by Nrf22010

    • Author(s)
      Takafumi Suzuki, Yukie Kawatani, Akira Ohkoshi, Vincent Kelly, Masayuki Yamamoto
    • Organizer
      9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
    • Place of Presentation
      京都
    • Year and Date
      2010-05-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice fed atherogenic plus high-fat diet2010

    • Author(s)
      Okada K, Sugimoto H, Warabi E, Gotoh N, Takahashi H, Utsunomiya H, Ishii T, Yamamoto M, Shoda J
    • Organizer
      The 8th JSH Single Topic Conference
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] エリスロポエチン産生細胞(Erythropoietin Producing Cells)2010

    • Author(s)
      山本雅之
    • Organizer
      第74回日本皮膚科学会学術大会
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] 転写因子Nrf2はヒト肺線癌細胞株A549でosteopontinの発現を増加させる2010

    • Author(s)
      光石陽一郎、本橋ほづみ、貫和敏博、山本雅之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 転写因子Nrf1とNrf2の中枢神経系における機能的差異の検証2010

    • Author(s)
      弘津陽介, 勝岡史城, 小林聡, 山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] 単離腎臓Erythropoietin産生細胞を用いたErythropoietin遺伝子制御機構の解明2010

    • Author(s)
      平野育生、潘小青、鈴木教郎、山嵜瞬、小原直、峯岸直子、山本雅之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 上皮細胞における転写因子Nrf2の活性化2010

    • Author(s)
      田口恵子、鈴木隆史、本橋ほづみ、山本雅之
    • Organizer
      日本生化学会東北支部会第76回例会・シンポジウム
    • Place of Presentation
      福島
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1-Nrf2 system and cancer2010

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      Tuesday Special Seminar, Cancer Research Institute of Seoul National University
    • Place of Presentation
      韓国、ソウル
    • Year and Date
      2010-06-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] ニトロ化環状ヌクレオチドによるタンパク質S-グアニル化を介する酸化ストレス適応応答の分子機序2010

    • Author(s)
      藤井重元、澤智裕、居原秀、Kit ITong、井田智章、岡本竜哉、Ahmed Khandaker Ahtesham、本橋ほづみ、山本雅之、赤池孝章
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] EPO研究のフロンティアと新しいEPOの可能性2010

    • Author(s)
      山本雅之
    • Organizer
      第19回腎とエリスロポエチン研究会
    • Place of Presentation
      品川
    • Year and Date
      2010-11-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      平成22年度ターゲットタンパクプロジェクト産学懇談会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Isolation and characterization of renal erythropoietin-producing cells : Contribution of HIF3a in vivo2010

    • Author(s)
      Pan X, Suzuki N, Hirano I, Yamazaki S, Yamashita T, Ohneda O, Minegishi N, Yamamoto M
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      分子生物学会第10回春季シンポジウム
    • Place of Presentation
      松島
    • Year and Date
      2010-06-08
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Stress response of megakaryocytes alters inherent reactivity of platelets2010

    • Author(s)
      Hozumi Motohashi, Rie Fujita, Hironori Satoh, Hiroyuki Aburatani, Masayuki Yamamoto
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 宿主におけるNrf2欠損はMDSCs細胞に著明な酸化ストレスの蓄積を誘導し、肺癌転移に対して有利な微小環境を創造する2010

    • Author(s)
      佐藤大希、森口尚、田口恵子、海老名雅仁、貫和敏博、山本雅之
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 発癌性物質や酸化ストレスに応答する生体防御系センサーの構造基盤2010

    • Author(s)
      黒河博文、本橋ほづみ、佐藤主税、山本雅之
    • Organizer
      ターゲットタンパク研究プログラム平成22年度成果発表会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-20
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸化ストレス応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      日本分子脳神経外科学会ランチョンセミナー
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] ニトロ化環状ヌクレオチドによるタンパク質S-グアニル化を介する酸化ストレス適応応答の分子機序2010

    • Author(s)
      藤井重元、澤智裕、居原秀、Kit I Tong、井田智章、岡本竜哉、Ahmed Khandaker Ahtesham、本橋ほづみ、山本雅之、赤池孝章
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Rescue of Epo-deficient mice from anemia by complementation with BAC transgene2010

    • Author(s)
      Yamazaki S, Suzuki N, Obara N, Pan X, Hirano I, Jishage K, Honda C, Minegishi N, Yamamoto M
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      平成22年度ターゲットタンパクプロジェクト産学懇談会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Functional Roles of NF-E2 p45 in the Regulation of Platelet Activity2010

    • Author(s)
      Rie Fujita, Mariko Takayama-Tsujimoto, Hozumi Motohashi, Masayuki Yamamoto
    • Organizer
      9th Japanese Biochemical Society Bio-Frontier Symposium 2010/5th International Symposium on GATA factors
    • Place of Presentation
      仙台
    • Year and Date
      2010-11-17
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Cytoprotective systems of skin by selenoproteins and Nrf22010

    • Author(s)
      Mariko Takayama, Takafumi Suzuki, Kai Takaya, Ryuhei Okuyama, Masayuki Yamamoto
    • Organizer
      9^<th> international Symposium on selenium in Biology and Medicine Selenium 2010
    • Place of Presentation
      京都
    • Year and Date
      2010-05-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸化ストレス応答の分子基盤2010

    • Author(s)
      山本雅之
    • Organizer
      日本分子脳神経外科学会ランチョンセミナー
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22659056
  • [Presentation] Regulation of erythropoietin gene expression in mouse2009

    • Author(s)
      Masayuki Yamamoto, Xiaoqing Pan, Syun Yamazaki, Ikuo Hirano, Naoko Minegishi, Norio Suzuki
    • Organizer
      8th International Luebeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
    • Place of Presentation
      University of Luebeck Germany
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1系と発癌2009

    • Author(s)
      山本雅之
    • Organizer
      68回 日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 116.The Nrf2-Keap1 system and cancer chemoprevention2009

    • Author(s)
      山本雅之
    • Organizer
      Special seminar at the Korean Society of Cancer Prevention, Lee Gil Ya Cancer and Diabetes Institute
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Structural basis and cancer-related mutations of the Nrf2-Keapl system2009

    • Author(s)
      Yamamoto M
    • Organizer
      John Hopkins University Seminar
    • Place of Presentation
      JHU Baltimore, USA
    • Year and Date
      2009-09-17
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keap1 System and Environmental Stress Response2009

    • Author(s)
      山本雅之
    • Organizer
      Symposium on "Comparative Animal Models of Leukemia and Lymphoma" at 14th International Association for Comparative Research on Leukemia and Related Diseases(IACRLRD)
    • Place of Presentation
      The Ohio State University USA
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The Nrf2-Keap1 system and cancer chemoprevention2009

    • Author(s)
      山本雅之
    • Organizer
      Special seminar at the Korean Society of Cancer Prevention, Lee Gil Ya Cancer and Diabetes Institute
    • Place of Presentation
      Incheon, Korea
    • Year and Date
      2009-11-20
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Dietary phosphorus regulates the detoxificartion-regulated gene expression through the activation of nuclear factor erythroid 2-related factor 2(Nrf2)in small intestine2009

    • Author(s)
      浦川千鶴、山本浩範、竹井悠一郎、竹谷豊、山本雅之、武田英二
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009

    • Author(s)
      鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] エリスロポエチン遺伝子の発現調節メカニズム2009

    • Author(s)
      山本雅之
    • Organizer
      第18回 腎とエリスロポエチン研究会
    • Place of Presentation
      品川
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Pivotal roles of small Maf proteins in the regulation of stress response genes2009

    • Author(s)
      Katsuoka F, Motohashi H, Nakayama H, Yamamoto M
    • Organizer
      The 1st International Symposium "Challenge to Medical Innovation"
    • Place of Presentation
      仙台
    • Year and Date
      2009-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The Nrf2-Keap1 system and oxidative stress response2009

    • Author(s)
      山本雅之
    • Organizer
      International Symposium 2009 on Signaling Functions of Reactive Oxygen Species
    • Place of Presentation
      Aso, Kumamoto
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 環境応答転写因子群と炎症・アレルギー2009

    • Author(s)
      山本雅之
    • Organizer
      第59回 日本アレルギー学会秋季学術大会特別企画シンポジウム2
    • Place of Presentation
      秋田
    • Year and Date
      2009-10-29
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Compound Deficiency of Nrf2 and Selenoproteins in Hematopoietic Cells Leads to Severe Defects in Erythroid and Lymphoid Development2009

    • Author(s)
      Kawatani Y, Suzuki T, Shimizu R, Kelly V, Yamamoto M.
    • Organizer
      The 51th ASH Annual Meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular Basis of Oxidative Stress Response2009

    • Author(s)
      山本雅之
    • Organizer
      International Symposium on Inflammation and Redox Signaling
    • Place of Presentation
      Culture Center, Seoul National University
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Identification of the target genes of transcription factor NF-E2 p45 in megakaryocytes2009

    • Author(s)
      藤田理恵、本橋ほづみ、油谷浩幸、山本雅之
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1系の分子構造基盤と発癌2009

    • Author(s)
      山本雅之
    • Organizer
      第9回 日本蛋白質科学会年会シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1環境応答系機能の分子・構造基盤2009

    • Author(s)
      山本雅之
    • Organizer
      蛋白研セミナー「活性酸素のシグナル伝達」
    • Place of Presentation
      大阪
    • Year and Date
      2009-11-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The Nrf2-Keap1 System and Cancer2009

    • Author(s)
      山本雅之
    • Organizer
      20th Asia Pacific Cancer Conference
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keap1 System and Environmental Stress Response2009

    • Author(s)
      山本雅之
    • Organizer
      Kansas University
    • Place of Presentation
      Kansas, USA
    • Year and Date
      2009-10-12
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Mutation of the lysine-specific demethylase 1 gene causes lineage-specific defects in zebrafish hematopoiesis2009

    • Author(s)
      Takeuchi, M., Kaneko, H., Kobayashi, M., Yamamoto, M.
    • Organizer
      日本発生生物学会第42回大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2誘導剤スクリーニング系の確立2009

    • Author(s)
      弘津陽介、勝岡史城、山本雅之
    • Organizer
      平成21年度合同班会議「遺伝子情報デコード」
    • Place of Presentation
      富山
    • Year and Date
      2009-06-14
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Roles of HIF-binding sequences in chromatin dynamics during activation of the hypoxia-inducible genes2009

    • Author(s)
      Norio Suzuki, Orjan Wrange, Katarina Gradin, Sergey Belikov, Kian Leong Lee, Masayuki Yamamoto, Lorenz Poellinger
    • Organizer
      8th International Luebeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
    • Place of Presentation
      Luebeck, Germany
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 環境応答転写因子2009

    • Author(s)
      山本雅之
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸化ストレス応答と発癌2009

    • Author(s)
      山本雅之
    • Organizer
      宮城県立がんセンターセミナー
    • Place of Presentation
      仙台
    • Year and Date
      2009-07-15
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1環境応答系機能の分子・構造基盤2009

    • Author(s)
      山本雅之
    • Organizer
      蛋白研セミナー「活性酸素のシグナル伝達」
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Comprehensive analysis of gene expression in central nervous system of small Maf compound mutant mice2009

    • Author(s)
      弘津陽介、勝岡史城、山本雅之
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Localization and expression pattern of erythropoietin producing cells in the adult and developing mouse retina2009

    • Author(s)
      N.Scheerer, N.Dunker, S.Imagawa, M.Yamamoto, N.Suzuki, J.
    • Organizer
      8th Int.Luebeck Conference Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
    • Place of Presentation
      University of Luebeck, Germany
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] エリスロポエチンの産生細胞と発現制御2009

    • Author(s)
      山本雅之
    • Organizer
      5回長時間透析研究会ランチョンセミナー
    • Place of Presentation
      横浜
    • Year and Date
      2009-11-08
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 環境適応・応答の分子機構2009

    • Author(s)
      山本雅之
    • Organizer
      第18回 翠嶂会・近畿大学大学院医学研究科 ハイテクリサーチセンター合同公開シンポジウム「ヒト疾患モデル研究の新展開」
    • Place of Presentation
      大阪
    • Year and Date
      2009-07-15
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 尿細管管腔内アルカリ化は脂肪酸結合アルブミンによる近位尿細管細胞からの活性酸素産生を、Pyk2経路を介して改善する。2009

    • Author(s)
      相馬友和、阿部倫明、森口尚、秋山泰利、豊原敬文、鈴木健弘、種本雅之、阿部高明、山本雅之、伊藤貞嘉
    • Organizer
      Kidney Frontier 2009
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Select heterozygous Keap1 mutations have a dominant-negative effect on wildtype Keap1 in vivo2009

    • Author(s)
      Takafumi Suzuki, Jonathan Maher, Yukie Kawatani, Masayuki Yamamoto
    • Organizer
      International symposium 2009 on Signaling Functions of Reactive Oxygen Species
    • Place of Presentation
      阿蘇
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2 acts as a novel metastasis suppressor in the lung2009

    • Author(s)
      Satoh H, Taguchi K, Moriguchi T, Suzuki T, Ebina M, Nukiwa T, Yamamoto M.
    • Organizer
      68回日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] エリスロポエチン遺伝子の発現調節メカニズム2009

    • Author(s)
      山本雅之
    • Organizer
      第18回 腎とエリスロポエチン研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-07
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009

    • Author(s)
      鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
    • Organizer
      第62回 日本酸化ストレス学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keap1 system and oxidative stress response2009

    • Author(s)
      山本雅之
    • Organizer
      International Symposium 2009 on Signaling Functions of Reactive Oxygen Species
    • Place of Presentation
      阿蘇
    • Year and Date
      2009-07-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2 is degraded by Keap1-independent proteasome pathway in the absence of small Maf proteins2009

    • Author(s)
      勝岡史城、中山博未、本橋ほづみ、山本雅之
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Genetically induced ER stress in a zebrafish model for human congenital disorders of glycosylation2009

    • Author(s)
      Mukaigasa, K., Li, L., Tsujita, T., Yamamoto, M., Kobayashi, M.
    • Organizer
      日本発生生物学会第42回大会
    • Place of Presentation
      新潟
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] A zebrafish model for human congenital disorder of glycosylation2009

    • Author(s)
      Mukaigasa K, Li L, Yagi H, Tsujita T, Kato K, Yamamoto M, Kobayashi M
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1系の分子構造基盤と発癌2009

    • Author(s)
      山本雅之
    • Organizer
      9回 日本蛋白質科学会年会シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2009-05-20
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 環境適応・応答の分子機構2009

    • Author(s)
      山本雅之
    • Organizer
      第18回 翠嶂会・近畿大学大学院医学研究科ハイテクリサーチセンター合同公開シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-06-13
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸化ストレス応答と病態2009

    • Author(s)
      山本雅之
    • Organizer
      第7回 Vascular and Brain Conference
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Identification of Nrf2-regulated genes in zebrafish2009

    • Author(s)
      Nakajima H, Nakajima-Takagi Y, Akiyama S, Wakasa T, Li L, Tsujita T, Kaneko H, Tamaru Y, Yamamoto M, Kobayashi M
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Keap1-Nrf2システムの多様な感知応答機構2009

    • Author(s)
      李麗、中島瞳、中島やえこ、岩本典子、熊谷嘉人、山本雅之、小林麻己人
    • Organizer
      平成21年度日本生化学会関東支部例会「若手が担う次世代型生化学研究」
    • Place of Presentation
      つくば
    • Year and Date
      2009-06-20
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular Basis of Oxidative Stress Response2009

    • Author(s)
      山本雅之
    • Organizer
      International Symposium on Inflammation and Redox Signaling
    • Place of Presentation
      Seoul National University Korea
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Roles of HIF-binding sequences in chromatin dynamics during activation of the hypoxia-inducible genes2009

    • Author(s)
      Norio Suzuki, Orjan Wrange, Katarina Gradin, Sergey Belikov, Kian Leong Lee, Masayuki Yamamoto, Lorenz Poellinger
    • Organizer
      8th Int.Luebeck Conference Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
    • Place of Presentation
      University of Luebeck, Germany
    • Year and Date
      2009-07-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] GATA factor switching during erythroid differentiation2009

    • Author(s)
      Masayuki Yamamoto, Takashi Moriguchi, Mikiko Suzuki, Ritsuko Shimizu
    • Organizer
      Gordon Conference on Red Blood Cells
    • Place of Presentation
      Biddeford, ME
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] マウス胎生期における小Maf群因子の機能 中山博未、勝岡史城、本橋ほづみ、山本雅之2009

    • Author(s)
      中山博未、勝岡史城、本橋ほづみ、山本雅之
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] エリスロポエチン遺伝子発現制御に十分な領域2009

    • Author(s)
      山崎瞬, 鈴木教郎, 小原直, 潘小青, 平野育生, 峯岸直子, 山本雅之
    • Organizer
      東北大学バイオサイエンスシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2009-06-16
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 含セレン蛋白質とNrf2による酸化ストレスに対する2段階防御2009

    • Author(s)
      鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
    • Organizer
      第82回 日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] TGF-beta suppresses transcription of Heme Oxigenase-1 through induction of MafK and Bach12009

    • Author(s)
      沖田結花里、鴨志田敦、鈴木裕之、伊東健、本橋ほづみ、五十嵐和彦、山本雅之、加藤光保
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] New function of host NRF2 in lung cancer2009

    • Author(s)
      佐藤大希, 田口恵子, 森口尚, 鈴木隆史, 海老名雅仁, 貫和敏博, 山本雅之
    • Organizer
      Interdisciplinary Force 学生成果発表会
    • Place of Presentation
      仙台
    • Year and Date
      2009-08-04
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] An easy and effective approach to rescue zebrafish mutant phenotypesvia transient transgenesis using Tol2 constructs2009

    • Author(s)
      Takeuchi M, Kaneko H, Nishikawa K, Kawakami K, Yamamoto M, Kobayashi M
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular basis for the Nrf2-Keap1 system function2009

    • Author(s)
      山本雅之
    • Organizer
      Experimental Biology 2009
    • Place of Presentation
      New Orleans, LA, USA
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] インチンコウ湯は肝Mrp2/MRP2の発現増加と毛細胆管膜への集積により胆汁酸非依存性の胆汁分泌を誘発する2009

    • Author(s)
      岡田浩介, 正田純一, 山本雅浩
    • Organizer
      第95回消化器病学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] Structural Basis of Nrf2-Keap1 Function2009

    • Author(s)
      山本雅之
    • Organizer
      Dasan 2009 Conferece on Bioremodelling
    • Place of Presentation
      Jeju, Korea
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Nrf2-Keap1システムと肺疾患2009

    • Author(s)
      山本雅之
    • Organizer
      第12回 質性肺炎細胞分子病態研究会「慢性炎症機序と呼吸器疾患」
    • Place of Presentation
      東京
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 遺伝子組換え実験および遺伝子組み換え動物モデルと医学研究の発展2009

    • Author(s)
      Masayuki Yamamoto, Tatsuhiro Shibata, Ohta Tsutomu, Kit Tong, Hirofumi Kurokawa, Takafumi Suzuki, Keiko Taguchi, Hozumi Motohashi
    • Organizer
      第68回 日本癌学会学術総会シンポジウム
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 転写因子Nrf2はコリンメチオニン欠乏食(MCDD)誘発非アルコール性脂肪性肝炎(NASH)を防御する2009

    • Author(s)
      杉本浩一, 岡田浩介, 正田純一, 蕨栄治, 石井哲郎, 山本雅之
    • Organizer
      第13回肝臓学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-21300275
  • [Presentation] マウス胎生期における小Maf群因子の機能2009

    • Author(s)
      勝岡史城、中山博未、本橋ほづみ、Engel JD, 山本雅之
    • Organizer
      日本生化学会東北支部 第75回例会・シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] エリスロポエチンの産生細胞と発現制御2009

    • Author(s)
      山本雅之
    • Organizer
      第5回長時間透析研究会ランチョンセミナー
    • Place of Presentation
      横浜
    • Year and Date
      2009-11-08
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 酸化ストレス応答と病態2009

    • Author(s)
      山本雅之
    • Organizer
      第7回Vascular and Brain Conference
    • Place of Presentation
      大阪
    • Year and Date
      2009-04-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Neuron-specific nrf1 knockout mice display neurodegeneration with nuclear accumulation of ubiquitin-positive proteins2009

    • Author(s)
      突出貴子、宮坂知宏、溝呂木達也、大辻摩希子、井原康夫、高島明彦、深水昭吉、山本雅之、小林聡
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Structural Basis of Nrf2-Keap1 Function2009

    • Author(s)
      山本雅之
    • Organizer
      Dasan 2009 Conferece on Bioremodelling
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2009-11-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The Nrf2-Keap1 System and Cancer2009

    • Author(s)
      山本雅之
    • Organizer
      第20回アジア太平洋癌学会/第18回日本腎泌尿器疾患予防医学研究会
    • Place of Presentation
      つくば
    • Year and Date
      2009-11-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular basis for the Nrf2-Keap1 system function2009

    • Author(s)
      山本雅之
    • Organizer
      Experimental Biology 2009
    • Place of Presentation
      New Orleans, LA, USA
    • Year and Date
      2009-04-18
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Luminal alkalization attenuates superoxide production induced by fatty acid-bound albumin in renal proximal tubular cells through Pyk2-dependent pathways2009

    • Author(s)
      Souma T, Abe M, Moriguchi T, Akiyama Y, Toyohara T, Shiwaku H, Suzuki T, Tanemoto M, Abe T, Sato H, Yamamoto M, Ito S
    • Organizer
      The 1st International Symposium "Challenge to Medical Innovation"
    • Place of Presentation
      仙台
    • Year and Date
      2009-12-07
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2 is degraded by Keap1-independent degradation pathway in the absence of small Maf proteins2009

    • Author(s)
      Fumiki Katsuoka, Hozumi Motohashi, Hiromi Nakayama, Masayuki Yamamoto
    • Organizer
      CDBIM symposium
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] ヒト先天性グリコシル化異常症の病態モデルゼブラフィッシュの解析2009

    • Author(s)
      向笠勝貴、辻田忠志、李麗、山本雅之、小林麻己人
    • Organizer
      平成21年度日本生化学会関東支部例会「若手が担う次世代型生化学研究」
    • Place of Presentation
      つくば
    • Year and Date
      2009-06-20
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答転写因子群と炎症・アレルギー2009

    • Author(s)
      山本雅之
    • Organizer
      第59回 日本アレルギー学会秋季学術大会 特別企画シンポジウム2
    • Place of Presentation
      秋田
    • Year and Date
      2009-10-29
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Regulation of erythropoietin gene expression in mouse2009

    • Author(s)
      Masayuki Yamamoto, Xiaoqing Pan, Syun Yamazaki, Ikuo Hirano, Naoko Minegishi, Norio Suzuki
    • Organizer
      8th International Luebeck Conference on the Pathophysiology and Pharmacology of Erythropoietin and other Hemopoietic Growth Factors
    • Place of Presentation
      Luebeck, Germany
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Nrf2-Keap1システムと肺疾患2009

    • Author(s)
      山本雅之
    • Organizer
      第12回 質性肺炎細胞分子病態研究会「慢性炎症機序と呼吸器疾患」
    • Place of Presentation
      東京
    • Year and Date
      2009-08-22
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Mouse Models of GATA1-related Leukemia2009

    • Author(s)
      山本雅之
    • Organizer
      14th International Association for Comparative Research on Leukemia, Related Diseases
    • Place of Presentation
      Comprehensive Cancer Center, The Ohio State University
    • Year and Date
      2009-10-14
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 含セレン蛋白質とNrf2による2段階生体防御機構2009

    • Author(s)
      鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
    • Organizer
      第62回 日本酸化ストレス学会
    • Place of Presentation
      福岡
    • Year and Date
      2009-06-11
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Nrf2-Keap1系と発癌2009

    • Author(s)
      山本雅之
    • Organizer
      第68回 日本癌学会学術総会 モーニングレクチャー
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-01
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] GFP transgenic zebrafish is a good tool to classify Nrf2 activators2009

    • Author(s)
      Li L, Nakajima N, Tusjita T, Yamamoto M, Kobayashi M
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] セレン蛋白質とNrf2による酸化ストレスに対する2段階防御2009

    • Author(s)
      鈴木隆史、川谷幸恵、Vincent Kelly、山本雅之
    • Organizer
      第82回 日本生化学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Rescue of Erythropoietin-Deficient Mice From Anemia by Complementation with BAC Transgene2009

    • Author(s)
      Shun Yamazaki, Norio Suzuki, Naoshi Obara, Xiaoqing Pan, Ikuo Hirano, Kou-ichi Jishage, Kurisu Honda, Naoko Minegishi, Masayuki Yamamoto
    • Organizer
      The 51th ASH Annual Meeting
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-05
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Cell tyte-specific Nrf2 activation : different feature in hepatocytes and epithelial cells2009

    • Author(s)
      Taguchi K, Yamamoto M.
    • Organizer
      CDBIM symposium
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境ストレス応答と化学発癌の分子メカニズム2009

    • Author(s)
      山本雅之
    • Organizer
      弘前大学セミナー
    • Place of Presentation
      弘前
    • Year and Date
      2009-05-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 遺伝子欠失マウスのレスキューと条件付きEpo遺伝子破壊マウスの樹立2009

    • Author(s)
      山嵜瞬, 鈴木教郎, 小原直, 潘小青, 平野育生, 峯岸直子, 山本雅之
    • Organizer
      第82回日本生化学会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Induction of Hyperproliferative Fetal Megakaryopoiesis by an N-terminally Truncated GATA1 Mutant2008

    • Author(s)
      Shimizu R, Engel JD, and Yamamoto M
    • Organizer
      The 16th Conference on Hemoglobin Switching, Asilomar
    • Place of Presentation
      California, USA
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Structural basis and cancer-related mutations of the Nrf2-Keapl system2008

    • Author(s)
      Yamamoto M
    • Organizer
      Scientific Colloquium, PHILIP MORRIS Research Laboratories GmbH
    • Place of Presentation
      Koln, Germany
    • Year and Date
      2008-09-26
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keapl Stress Response System : Molecular Basis of Adaptive Responses to Food and Oxygen2008

    • Author(s)
      Yamamoto M
    • Organizer
      11-SAC Seminar
    • Place of Presentation
      Danilovskaya Hotel, Moscow, Russian
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Gata1 Gene Regulation and GATA1-related Leukemia2008

    • Author(s)
      Yamamoto M, Moriguchi T, Suzuki M. and Shimizu R
    • Organizer
      The 16th Conference on Hemoglobin Switching Asilomar
    • Place of Presentation
      California, USA
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keap1 System and Cancer2008

    • Author(s)
      Yamamoto M
    • Organizer
      AACR conference on "Chemical and Biological Aspect of Inflammation and Cancer"
    • Place of Presentation
      JW Marriott Ihilani Resort & Spa at Ko Olina, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The Nrf2-Keap 1 system of oxidative/electrophilic stress response: mechanism and diseases.2008

    • Author(s)
      Tong KI., Yamamoto M
    • Organizer
      Joint Annual Meeting of the Molecular Biology Society of Japan and the Japanese Biochemical Society. 2008(BMB2008)
    • Place of Presentation
      Kobe Port Island, Japan
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第17回 日本産婦人科・新生児血液学会シンポジウム「ダウン症候群と一過性骨髄造血(TAM)」
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      第5回フリーラジカルと脳疾患 東日本研究会特別講演
    • Place of Presentation
      経団連会館、大手町
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      臨床研セミナー
    • Place of Presentation
      (財)東京都医学研究機構 東京都臨床医学総合研究所
    • Year and Date
      2007-08-10
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrf2 system: a hinge and latcn mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 3rd DECODE for Biological Responses International Meeting.
    • Place of Presentation
      Odaiba, Tokyo
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      日本生化学会東北支会シンポジウム
    • Place of Presentation
      艮陵会館、仙台
    • Year and Date
      2007-05-12
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      National University of Singapore-Tohoku University/Centre of Excellence Joint Symposium"Basic and Clinical Research on Signal Transduction Diseases"
    • Place of Presentation
      Centre for Life Sciences, National University of Singapore, Singapore, Singapore
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrt2 system:a hinge and latch mechanism2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 3rd DECODE for Biological Responses Intemational Meeting.
    • Place of Presentation
      Odaiba, Tokyo
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 細胞の癌化とその抑制における転写因子の役割2007

    • Author(s)
      山本雅之
    • Organizer
      文部科学省がん特定領域研究「遺伝情報システム異常と発がん」
    • Place of Presentation
      癌研究会吉田富三記念講堂、有明
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 細胞の癌化とその抑制における転写因子の役割2007

    • Author(s)
      山本雅之
    • Organizer
      文部科学省がん特定領域研究「遺伝情報システム異常と発がん」
    • Place of Presentation
      癌研究会吉田富三記念講堂、有明
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 環境応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第5回RCGMフロンティアシンポジウム「ゲノム医学一基礎から未来医療へ」
    • Place of Presentation
      埼玉医科大学日高キャンパス創立30周年記念講堂、日高市
    • Year and Date
      2007-07-27
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 酸化ストレス応答と呼吸器疾患2007

    • Author(s)
      山本雅之
    • Organizer
      第47回日本呼吸器学会学術講演会
    • Place of Presentation
      東京フォーラム
    • Year and Date
      2007-05-11
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第50回 東北小児白血病研究会
    • Place of Presentation
      かんぽヘルスプラザ仙台
    • Year and Date
      2007-04-28
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      第5回フリーラジカルと脳疾患 東日本研究会特別講演
    • Place of Presentation
      経団連会館、大手町
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masavuki Yamamoto.
    • Organizer
      NIEHS Seminar.
    • Place of Presentation
      Research Triangle Park (RTP), USA
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 酸化ストレス応答の分子基盤と疾患2007

    • Author(s)
      山本雅之
    • Organizer
      CKDと心血管イベントExpert Meeting特別講演
    • Place of Presentation
      東京會舘
    • Year and Date
      2007-11-27
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      臨床研セミナー
    • Place of Presentation
      (財)東京都医学研究機構 東京都臨床医学総合研究所
    • Year and Date
      2007-08-10
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The NrF2-Keap1 Stress Response System.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 23rd Kumamoto Medical Bioscience Symposium on New Insights into Metabolic Disorders and Vascular Disease.
    • Place of Presentation
      Kumamoto
    • Year and Date
      2007-11-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechani sm.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Adjunct Professor Lecture at Johns Hopkins University Blumberg School of Public Health, Baltimore
    • Place of Presentation
      Johns Hopkins University Blumberg School of Public Health, Baltimore, USA
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The environmental response to food and oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      JST-ERATO Environmental Response Project International Symposium on "The Environmental Response".
    • Place of Presentation
      EPOCHAL Tsukuba International Congress Center, Tsukuba
    • Year and Date
      2007-12-21
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] The environmental response to food and oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      JST-ERATO Environmental Response Project International Symposium on "The Environmental Response"
    • Place of Presentation
      EPOCHAL Tsukuba International Congress Center, Tsukuba
    • Year and Date
      2007-12-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Distinguished Professor's Seminar.
    • Place of Presentation
      University of Arizona, Tucson, USA
    • Year and Date
      2007-11-02
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      第5回フリーラジカルと脳疾患 東日本研究会特別講演
    • Place of Presentation
      経団連会館、大手町
    • Year and Date
      2007-07-28
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Molecular Mechanisms of Adaptive Responses to Food and Oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The International Conference on Food Factors for Health Promotion(ICOFF2007)
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] The Nrf2-Keapl Stress Response System.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 23rd Kumamoto Medical Bioscience Symposium on New Insights into Metabolic Disorders and Vascular Disease.
    • Place of Presentation
      Kumamoto
    • Year and Date
      2007-11-12
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      日本生化学会東北支会シンポジウム
    • Place of Presentation
      艮陵会館、仙台
    • Year and Date
      2007-05-12
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 酸化ストレス応答と呼吸器疾患2007

    • Author(s)
      山本雅之
    • Organizer
      第47回日本呼吸器学会学術講演会
    • Place of Presentation
      東京フォーラム
    • Year and Date
      2007-05-11
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] GATA因子と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第2回 つくば医科学研究交流会 ランチョンセミナー
    • Place of Presentation
      三菱化学つくばクリエーションセンター
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Distinguished Professor's Seminar.
    • Place of Presentation
      University of Arizona, Tucson, USA
    • Year and Date
      2007-11-02
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Adjunct Professor Lecture at Johns Hopkins University Blumberg School of Public Health, Baltimore
    • Place of Presentation
      Johns Hopkins University Blumberg School of Public Health, Baltimore, USA
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Adjunct Professor Lecture at Johns Hopkins University Blumberg School of Public Health, Baltimore
    • Place of Presentation
      Johns Hopkins University Blumberg School of Public Health, Baltimore, USA
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Molecular Mechanisms of Adaptive Responses to Food and Oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The International Conference on Food Factors for Health Promotion (ICOFF2007)
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      National University of Singapore - Tohoku University/Centre of Excellence Joint Symposium "Basic and Clinical Research on Signal Transduction Diseases".
    • Place of Presentation
      Centre for Life Sciences, National University of Singapore, Singapore, Singapore
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 親電子性物質・酸化ストレス応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      循環器内科リサーチセミナー
    • Place of Presentation
      東北大学
    • Year and Date
      2007-05-30
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Genetic Analysis of Mouse GATA-related Leukemia and Leukemic Stem Cells.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Gordon Research Conference on Red Cells, Centre Paul Langevin in Aussois.
    • Place of Presentation
      Aussois, France
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] GATA因子と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第2回つくば医科学研究交流会ランチョンセミナー
    • Place of Presentation
      三菱化学つくばクリエーションセンター
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 酸化ストレス応答の分子基盤と疾患2007

    • Author(s)
      山本雅之
    • Organizer
      CKDと心血管イベントExpert Meeting特別講演
    • Place of Presentation
      東京會舘
    • Year and Date
      2007-11-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Genetic Analysis of Mouse GATA-related Leukemia and Leukemic Stem Cells.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Gordon Research Conference on Red Cells, Centre Paul Langevin in Aussois.
    • Place of Presentation
      Aussois, France
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The environmental response to food and oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      JST-ERATO Environmental Response Project International Symposium on "The Environmental Response".
    • Place of Presentation
      EPOCHAL Tsukuba International Congress Center, Tsukuba
    • Year and Date
      2007-12-21
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第50回 東北小児白血病研究会
    • Place of Presentation
      かんぽヘルスプラザ仙台
    • Year and Date
      2007-04-28
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      東海医学会講演会
    • Place of Presentation
      東海大学
    • Year and Date
      2007-11-13
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 環境応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第5回RCGMフロンティアシンポジウム「ゲノム医学一基礎から未来医療へ」
    • Place of Presentation
      埼玉医科大学日高キャンパス創立30周年記念講堂、日高市
    • Year and Date
      2007-07-27
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      NIEHS Seminar.
    • Place of Presentation
      Research Triangle Park(RTP), USA
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Genetic Analysis of Mouse GATA-related Leukemia and Leukemic Stem Cells.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Gordon Research Conference on Red Cells, Centre Paul Langevin in Aussois.
    • Place of Presentation
      Aussois, France
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Functional analyses of GATA-2 with knockdown and conditional knockout mice.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      EMBO WORKSHOP ON The Role and Control of GATA Factors in Tissue Development and Disease.
    • Place of Presentation
      Capri, Italy
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 親電子性物質・酸化ストレス応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第7回 システム生物医学研究会
    • Place of Presentation
      東京大学先端科学技術研究センター システム生物医学ラボラトリー主催、箱根湯本
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      臨床研セミナー
    • Place of Presentation
      (財)東京都医学研究機構 東京都臨床医学総合研究所
    • Year and Date
      2007-08-10
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 酸化ストレス応答の分子基盤と疾患2007

    • Author(s)
      山本雅之
    • Organizer
      CKDと心血管イベントExpert Meeting特別講演
    • Place of Presentation
      東京會舘
    • Year and Date
      2007-11-27
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      NIEHS Seminar.
    • Place of Presentation
      Research Triangle Park (RTP), USA
    • Year and Date
      2007-10-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第17回 日本産婦人科・新生児血液学会シンポジウム「ダウン症候群と一過性骨髄造血(TAM)」
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      Distinguished Professor's Seminar.
    • Place of Presentation
      University of Arizone, Tucson, USA
    • Year and Date
      2007-11-02
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 酸化ストレス応答と呼吸器疾患2007

    • Author(s)
      山本雅之
    • Organizer
      第47回日本呼吸器学会学術講演会
    • Place of Presentation
      東京フォーラム
    • Year and Date
      2007-05-11
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第50回東北小児白血病研究会
    • Place of Presentation
      かんぽヘルスプラザ仙台
    • Year and Date
      2007-04-28
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・酸化ストレス応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第7回 システム生物医学研究会
    • Place of Presentation
      東京大学先端科学技術研究センター システム生物医学ラボラトリー主催、箱根湯本
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Functional analyses of GATA-2 with knockdown and conditional knockout mice.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      EMBO WORKSHOP ON The Role and Control of GATA Factors in Tissue Development and Disease.
    • Place of Presentation
      Capri, Italy
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] The Nrf2-Keap1 Stress Response System.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 23rd Kumamoto Medical Bioscience Symposium on New Insights into Metabolic Disorders and Vascular Disease.
    • Place of Presentation
      Kumamoto
    • Year and Date
      2007-11-12
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Molecular Mechanisms of Adaptive Responses to Food and Oxygen.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The International Conference on Food Factors for Health Promotion (ICOFF2007)
    • Place of Presentation
      Kyoto
    • Year and Date
      2007-11-29
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] GATA因子と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第2回つくば医科学研究交流会 ランチョンセミナー
    • Place of Presentation
      三菱化学つくばクリエーションセンター
    • Year and Date
      2007-11-10
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keapl-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      National University of Singapore-Tohoku University/Centre of Excellence Joint Symposium "Basic and Clinical Research on Signal Transduction Diseases".
    • Place of Presentation
      Centre for Life Sciences, National University of Singapore, Singapore, Singapore
    • Year and Date
      2007-09-05
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・酸化ストレス応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      循環器内科リサーチセミナー
    • Place of Presentation
      東北大学
    • Year and Date
      2007-05-30
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 環境応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第5回RCGMフロンティアシンポジウム「ゲノム医学-基礎から未来医療へ」
    • Place of Presentation
      埼玉医科大学日高キャンパス創立30周年記念講堂、日高市
    • Year and Date
      2007-07-27
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Functional analyses of GATA-2 with knockdown and conditional knockout mice.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      EMBO WORKSHOP ON The Role and Control of GATA Fact ors in Tissue Development and Disease.
    • Place of Presentation
      Capri, Italy
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・酸化ストレス応答の分子機構2007

    • Author(s)
      山本雅之
    • Organizer
      第7回システム生物医学研究会
    • Place of Presentation
      東京大学先端科学技術研究センターシステム生物医学ラボラトリー主催、箱根湯本
    • Year and Date
      2007-11-21
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system : a hinge and latch mechanism2007

    • Author(s)
      Yamamoto M.
    • Organizer
      Adjunct Professor Lecture at Johns Hopkins University Blumberg School of Public Health
    • Place of Presentation
      ボルチモア(米国)
    • Year and Date
      2007-10-31
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.2007

    • Author(s)
      Masayuki Yamamoto.
    • Organizer
      The 3^<rd> DECODE for Biological Responses International Meeting.
    • Place of Presentation
      Odaiba, Tokyo
    • Year and Date
      2007-08-04
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本 雅之
    • Organizer
      東海医学会講演会
    • Place of Presentation
      東海大学
    • Year and Date
      2007-11-13
    • Data Source
      KAKENHI-PROJECT-18659082
  • [Presentation] 細胞の癌化とその抑制における転写因子の役割2007

    • Author(s)
      山本雅之
    • Organizer
      文部科学省がん特定領域研究「遺伝情報システム異常と発がん」
    • Place of Presentation
      癌研究会吉田富三記念講堂、有明
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・酸化ストレス応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      循環器内科リサーチセミナー
    • Place of Presentation
      東北大学
    • Year and Date
      2007-05-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      日本生化学会東北支会シンポジウム
    • Place of Presentation
      長陵会館、仙台
    • Year and Date
      2007-05-12
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] GATA転写因子群の機能異常と白血病2007

    • Author(s)
      山本雅之
    • Organizer
      第17回 日本産婦人科・新生児血液学会シンポジウム「ダウン症候群と一過性骨髄造血(TAM)」
    • Place of Presentation
      富山国際会議場
    • Year and Date
      2007-06-30
    • Data Source
      KAKENHI-PROJECT-19GS0312
  • [Presentation] 親電子性物質・活性酸素応答の分子メカニズム2007

    • Author(s)
      山本雅之
    • Organizer
      東海医学会講演会
    • Place of Presentation
      東海大学
    • Year and Date
      2007-11-13
    • Data Source
      KAKENHI-PROJECT-17013017
  • [Presentation] Nrf2 regulates glycogen metabolism in skeletal muscle

    • Author(s)
      Akira Uruno, Yoko Yagishita, Masayuki Yamamoto
    • Organizer
      The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Cambridge, UK
    • Year and Date
      2015-01-06 – 2015-01-08
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] 複合遺伝子欠失レスキュー法による転写因子Nrf2の新規生理機能探索

    • Author(s)
      鈴木隆史、平本圭一郎、長沼絵理子、高橋信行、佐藤博、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都、国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] 抗酸化ストレス転写因子Nrf2欠損マウス由来肺腫瘍はKras経路の抑制と肺腺癌特異的な遺伝子発現低下をきたす

    • Author(s)
      佐藤大希、森口尚、海老名雅仁、山本雅之
    • Organizer
      第53回日本呼吸器学会学術総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2 regulates glucose metabolism-related genes

    • Author(s)
      Yoko Yagishita, Akira Uruno, Fumiki Katsuoka, Ryo Funayama, Keiko Nakayama, Masayuki Yamamoto
    • Organizer
      The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Cambridge, UK
    • Year and Date
      2015-01-06 – 2015-01-08
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] EVI1陽性白血病においてEVI1発現量が白血病細胞の分化形態を規定する

    • Author(s)
      鈴木未来子、片山紗乙莉、山崎博未、James Douglas Engel、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2014-10-16 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26670463
  • [Presentation] Multiple Sensor Mechanism of the Keap1-Nrf2 System.

    • Author(s)
      8.Takafumi Suzuki, Kai Takaya, Ryota Saito, Keiichiro Hiramoto, Tatsuro Iso and Masayuki Yamamoto.
    • Organizer
      Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research”
    • Place of Presentation
      京都、国際高等研究所
    • Year and Date
      2014-11-11 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Keap1 Cys273 and Cys288 are functional sensors for 15d-PGJ2 to activate Nrf2 signaling.

    • Author(s)
      9.Takafumi Suzuki, Ryota Saito, Kei-ichiro Hiramoto, Tatsuro Iso, Masayuki Yamamoto.
    • Organizer
      The Keap1/Nrf2 Pathway in Health and Disease
    • Place of Presentation
      Robinson College, Cambridge, UK
    • Year and Date
      2015-01-06 – 2015-01-08
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] シス配列多様性に依存したGATA1-DNA結合親和性修飾機構の生理機能解析

    • Author(s)
      長谷川 敦史, 清水 律子, 金子 寛, 黒河 博文, 山本 雅之
    • Organizer
      BIA Symposium 2012
    • Place of Presentation
      明治記念館
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] GATA1アミノ末端側亜鉛フィンガーによるDNA結合親和性調節機構が赤血球分化に果たす役割

    • Author(s)
      長谷川敦史, 金子寛, 山本雅之, 清水律子
    • Organizer
      日本生化学会東北支部第79回例会・シンポジウム
    • Place of Presentation
      東北大学さくらホール
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] Epo遺伝子転写調節領域の探索

    • Author(s)
      平野育生, 鈴木教郎, 峯岸直子, 山本雅之, 清水律子
    • Organizer
      第11回がんとハイポキシア研究会
    • Place of Presentation
      東北大学さくらホール
    • Data Source
      KAKENHI-PROJECT-24659142
  • [Presentation] HER3陽性の胆道癌に対する分子標的治療pertuzumabの効果

    • Author(s)
      川本 徹,山本雅一,正田純一
    • Organizer
      第56回日本消化器病学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-23 – 2014-10-26
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Presentation] Molecular Basis of Environmental Response by Keap1-Nrf2 System

    • Author(s)
      Yamamoto M
    • Organizer
      RCCH symposium
    • Place of Presentation
      Seoul, Korea
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] GATA2 distal hematopoietic enhancer induces EVI1-expressing leukemia in inv(3)(q21;q26)

    • Author(s)
      Mikiko Suzuki, Hiromi Yamazaki, Saori Katayama, Akihito Otsuki, Ritsuko Shimizu, Emery H. Bresnick, James Douglas Engel and Masayuki Yamamoto
    • Organizer
      The 19th Hemoglobin Switching Conference
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2014-09-05 – 2014-09-07
    • Data Source
      KAKENHI-PROJECT-26670463
  • [Presentation] 胆道癌における高感度診断システムの開発:新しい腫瘍マーカーとしてのWFA-sialyl MUC1の意義

    • Author(s)
      樋口亮太,正田純一,山本雅一
    • Organizer
      第50回日本胆道学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-09-26 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-26293297
  • [Presentation] Renal erythropoietin producing cells for anemia and fibrosis

    • Author(s)
      Masayuki Yamamoto
    • Organizer
      ISN( International Society of Nephrology ) Nexus Symposium
    • Place of Presentation
      Bergamo, Italy
    • Year and Date
      2014-04-05 – 2014-04-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 赤血球系転写因子の発現制御とエピジェネティクス機構

    • Author(s)
      山本雅之
    • Organizer
      第7回日本エピジェネティクス研究会年会
    • Place of Presentation
      奈良県新公会堂
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] Nrf2による糖尿病の発症抑制作用

    • Author(s)
      宇留野晃、古澤祐樹、柳下陽子、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府、京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] 酸化ストレス応答の分子メカニズムと病態

    • Author(s)
      山本雅之
    • Organizer
      第50回日本臨床分子医学会学術集会
    • Place of Presentation
      東京国際フォーラム
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] 転写因子Nrf2による炎症性サイトカイン遺伝子の発現抑制

    • Author(s)
      小林枝里, 鈴木隆史, 舟山亮, 長嶋剛史, 中山啓子, 山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都、国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] 門脈枝結紮による代償性肝肥大におけるNrf2の役割

    • Author(s)
      白崎圭一、田口恵子、本橋ほづみ、海野倫明、山本雅之
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] エリスロポエチン遺伝子の発現制御メカニズム

    • Author(s)
      山本雅之
    • Organizer
      第86回日本内分泌学会学術集会
    • Place of Presentation
      仙台国際センター
    • Invited
    • Data Source
      KAKENHI-PROJECT-24249015
  • [Presentation] CRISPR/Cas9システムを用いたNrf2点変異マウスの作製

    • Author(s)
      守田匡伸、大槻晃史、鈴木隆史、須田博美、鈴木未来子、清水律子、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都、国立京都国際会館
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26460354
  • [Presentation] Nrf2による酸化ストレス糖尿病モデルマウスの膵β細胞保護

    • Author(s)
      柳下陽子、宇留野晃、福富俊明、菅原明、山本雅之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府、京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-26893008
  • [Presentation] Genetic activation of hypoxia-signaling restores erythropoietin synthesis in renal myofibroblasts.

    • Author(s)
      5.Souma T, Nezu M, Ito S, Suzuki N, and Yamamoto M.
    • Organizer
      ASN renal week
    • Place of Presentation
      Philadelphia, Pennsylvania, USA
    • Year and Date
      2014-11-11 – 2014-11-16
    • Data Source
      KAKENHI-PLANNED-26111002
  • []

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  • []

  • 1.  TAKAHASHI Satoru (50271896)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  ISHII Syunsuke (00124785)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  HAYASHI Norio (00004606)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 4.  IGARASHI Kazuhiko (00250738)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 5.  RITSUKO Shimizu (40226262)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 65 results
  • 6.  FUJII-KURIYAMA Yoshiaki (00098146)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  MOTOHASHI Hozumi (00282351)
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  • 180.  陰山 聡一 (80390863)
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  • 181.  武田 憲彦 (40422307)
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  • 182.  西田 基宏 (90342641)
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  • 183.  酒井 俊 (30282362)
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  • 184.  磯辺 智範 (70383643)
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  • 185.  斎藤 芳郎 (70357060)
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  • 186.  SUEMATSU makoto
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    # of Collaborated Products: 0 results
  • 187.  SOGA tomoyoshi
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    # of Collaborated Products: 0 results
  • 188.  TANIGUCHI naoyuki
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    # of Collaborated Products: 0 results
  • 189.  SEKINE Hiroki
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    # of Collaborated Products: 10 results
  • 190.  HIRANO Ikuo
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    # of Collaborated Products: 10 results
  • 191.  NEZU Masahiro
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  • 192.  HARTMUT Beug
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    # of Collaborated Products: 0 results
  • 193.  PATIENT Roger
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  • 194.  ENGEL J.Douglas
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  • 195.  KANEMAKI Misao
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    # of Collaborated Products: 0 results
  • 196.  HARADA Tamanori
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    # of Collaborated Products: 0 results
  • 197.  KAGAMI Yoshihiro
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    # of Collaborated Products: 0 results
  • 198.  DATE Fumiko
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    # of Collaborated Products: 0 results
  • 199.  SEKI Shiori
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  • 200.  HIRAMOTO Keiichiro
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  • 201.  蓬田 健太郎
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  • 202.  ROMEO PaulーH
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  • 203.  ENCEL James
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  • 204.  ENGEL James Douglas
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  • 205.  ROMEO Poul Henri
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  • 206.  ENGEL James.
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  • 207.  ENGEL James
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    # of Collaborated Products: 0 results
  • 208.  プーシエント ロジャー
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    # of Collaborated Products: 0 results
  • 209.  エンゲル ダグラス
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  • 210.  TAKAMURA Toshinari
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    # of Collaborated Products: 1 results
  • 211.  TANAKA Tetsuhiro
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    # of Collaborated Products: 1 results
  • 212.  MARUYAMA Atsushi
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    # of Collaborated Products: 1 results
  • 213.  OKITSU Yoko
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  • 214.  ISHIJIMA Yasushi
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  • 215.  OHMORI Shinya
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    # of Collaborated Products: 1 results
  • 216.  TAKAGI Kenji
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    # of Collaborated Products: 1 results
  • 217.  TANAKA Minoru
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    # of Collaborated Products: 1 results
  • 218.  ITOH Tohru
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    # of Collaborated Products: 1 results
  • 219.  HAMADA Shin
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    # of Collaborated Products: 1 results
  • 220.  HIRATA Yukiyo
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    # of Collaborated Products: 1 results
  • 221.  LI Ying ji
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    # of Collaborated Products: 1 results
  • 222.  相馬 友和
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    # of Collaborated Products: 2 results
  • 223.  大槻 晃史
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    # of Collaborated Products: 1 results
  • 224.  田中 啓二
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    # of Collaborated Products: 1 results
  • 225.  稲城 玲子
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  • 226.  丸山 和一
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    # of Collaborated Products: 1 results
  • 227.  宮崎 陽一
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    # of Collaborated Products: 1 results
  • 228.  安田 大輔
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  • 229.  小池 正人
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  • 230.  伊藤 光宏
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    # of Collaborated Products: 1 results
  • 231.  三村 純正
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  • 232.  小柴 生造
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    # of Collaborated Products: 1 results
  • 233.  松丸 大輔
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    # of Collaborated Products: 1 results
  • 234.  坂井 詠子
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    # of Collaborated Products: 1 results
  • 235.  岡元 邦彰
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    # of Collaborated Products: 1 results
  • 236.  西下 一久
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    # of Collaborated Products: 1 results
  • 237.  筑波 隆幸
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    # of Collaborated Products: 1 results
  • 238.  横井 雅幸
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    # of Collaborated Products: 1 results
  • 239.  石井 幸雄
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    # of Collaborated Products: 1 results
  • 240.  沼澤 聡
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    # of Collaborated Products: 1 results
  • 241.  田邉 修
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    # of Collaborated Products: 1 results
  • 242.  石田 典子
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    # of Collaborated Products: 1 results
  • 243.  水島 恒裕
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    # of Collaborated Products: 1 results
  • 244.  宮島 篤
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    # of Collaborated Products: 1 results
  • 245.  森 俊雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 246.  正宗 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 247.  中山 啓子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 248.  舟山 亮
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 249.  稲垣 弘文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 250.  吾妻 安良太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 251.  川田 智之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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