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YAMAMURA KENICHI  山村 研一

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… Alternative Names

山村 研一  ヤマムラ ケンイチ

YAMAMURA Kenichi  山村 研一

YAMAMURA Ken-ichi  山村 研一

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Researcher Number 90115197
Other IDs
External Links
Affiliation (Current) 2025: 熊本大学, 生命資源研究・支援センター, 客員教授
Affiliation (based on the past Project Information) *help 2019 – 2021: 熊本大学, 生命資源研究・支援センター, 客員教授
2017: 熊本大学, 発生医学研究所, 教授
2013 – 2015: 熊本大学, 生命資源研究・支援センター, シニア教授
2014: 熊本大学, 学内共同利用施設等, その他
2009 – 2014: Kumamoto University, 生命資源研究・支援センター, 教授 … More
2012: 熊本大学, 生命資源研究支援センター, 教授
2011: 熊本大学, 生命資源研究・支援センター, 部長
2009: 熊本大学, 教授
2005 – 2008: 熊本大学, 発生医学研究センター, 教授
2007: 熊本大学, 学内共同利用施設, 教授
2000 – 2003: KUMAMOTO UNIVERSITY, INSITUTE OF MOLECULAR EMBRYOLOGY AND GENETICS, PROFESSOR, 発生医学研究センター, 教授
1986 – 2002: 熊本大学, 医学部, 教授
1996: 熊本大学医学部, 遺伝発生研究所, 教授
1993: 熊本大学医学部, 付属遺伝発生医学研究施設, 教授
1992: 熊本大学, 医学部・附属遺伝発生医学研究施設, 教授
1990 – 1991: 熊本大学, 医学部・附属遺伝医学研究施設, 教授
1990: 熊本大学, 遺伝研究所, 教授
1989: 熊本大学, 医学部附属遺伝医学研究施設細胞遺伝, 教授
1988 – 1989: 熊本大学, 医学部・附属遺伝医学研究施設細胞遺伝, 教授
1988: 熊本大学, 医学部付属遺伝医学研究所, 教授
1987: 熊本大学, 医学部附属遺伝医学研究施設・遺伝研究部, 教授
1986: 熊本大, 医学部, 教授
1986: 熊本大学医学部附属遺伝医学研究施設, 遺伝研究部, 教授 Less
Review Section/Research Field
Principal Investigator
Human genetics / Laboratory animal science / Laboratory animal science / Biological Sciences
Except Principal Investigator
General anatomy (including Histology/Embryology) / Basic Section 48040:Medical biochemistry-related / Pharmacology in pharmacy / 畜産学(含草地学) / Biological Sciences / Developmental biology … More / Applied animal science / Laboratory animal science / プラズマ理工学 / Human genetics / Pediatrics / Orthopaedic surgery / Human genetics / General pharmacology / Neurochemistry/Neuropharmacology Less
Keywords
Principal Investigator
トランスジェニックマウス / 遺伝子トラップ / ES細胞 / 癌遺伝子 / BAC / 相同遺伝子組換え / B型肝炎ウイルス / GENE TRAP / トランスサイレチン / 相同組換え … More / Cre-loxP / myc遺伝子 / YAC / ES CELL / 発生 / 細菌人工染色体 / キメラマウス / 悪性リンパ腫 / 家族性アミロイドポリニューロパシー / FAP / Transgenic mouse / ポジショナルクローニング / ES cell / ヒト化マウス / 野生マウス / 膵炎 / 標的遺伝子組換え / 胚幹細胞 / Familial amyloidotic polyneuropathy / RNAi / transthyretin / CPHPC / 血清アミロイドP成分 / マイクロインジェクション / TRANSGENIC MOUSE / 酵母人工染色体 / 変異マウス / loxP / Cre / 胚葉体 / EMBRYOID BODY / 胚様体 / ゲノム解析 / 形態形成 / transgenic mouse / homologous recombination / 遺伝病 / gene trap / ネオ耐性遺伝子 / 糖尿病 / 可変型相同組換え / 遺伝子破壊マウス / 遺伝的背景 / Serum amyloid P component / Amyloid / Transthyretin / アミロイド / トランスジュニックマウス / 家族性アミロイドポリニュ-ロパシ- / Genetic disease / マウス受精卵 / プレアルブミン / 遺伝子置換 / マウス肝炎ウイルス / 2本鎖RNA / serum amyloid P component / 家族性アミロイドニューロパシー / 腸内細菌叢 / Cre-IoxP / 家族性アミロイドポリニューロパチー / MICROINJECTION / T COMPLEX / OUAKING / tail kinks / ミエリン / T complex / quaking / ANTIOXIDANT / TRANSTHYRETIN / AMYLOIDOSIS / 抗酸化剤 / アミロイドーシス / ARTIFICIAL CHROMOSOME / CHIMERIC MOUSE / KNOCKOUT MOUSE / RECOMBINATIO / CRE-LOXP / 人工細菌染色体 / 遺伝子挿入 / cre-rexP / 遺伝子組換え 遺伝子破壊マウス キメラマウス / 遺伝子トラップ Cre-loxP / positional cloning / development / mutant mouse / 胚発生 / ボンショナルクローニング / RECOMBINATION / 標的変異マウス / 組換え / Mutant / Positional cloning / Development / tコンプレックス / T / 突然変異 / 突然変異体 / MODEL MOUSE / MORPHOGENESIS / lacZ / EC細胞 / モデルマウス / yeast artificial chromosome / Gene targeting / 疾患モデル / 人口酵母染色体 / 標的組換え / gene targetting / germ-line chimera / transgenic mice / insertional mutation / 挿入突然変異マウス / 受精卵 / 挿入突然変異 / 悪性リンパ腫瘍 / トランシジェニックマウス / エンハンサー / 免疫グロブリン遺伝子 / 染色体相互転座 / 可変型相同組替え / 行動 / 行動パターン / ノックアヴトマウス / ノックアウトマウス / ES 細胞 / キメラ / アミロイドポリニューロパチー / 遊走能 / 膵腺房細胞 / トリプシンインヒビター / 遊走脳 / 血管平滑筋 / 狭心症 / 増殖因子 / 肺気腫 / マクロファージ / Prss1 / セルレイン / epidermal growth factor receptor / 可変型遺伝子トラップ / オートファジー / 条件的遺伝子破壊 / Atg5 / Spink3 / Abhd2 / ノックアウト / トランスジェニック / 遺伝子改変マスウ / 組織診断 / 病理形態学 / データベース / 遺伝学的モニタリング / 微生物学的モニタリング / 凍結保存 / 遺伝子改変マウス / 生殖系列 / qkl遺伝子 / 遺伝子組換え / マウス / レトロウイルスベクター / レロトウイルスベクター / ニワトリ / ゼブラフィッシュ / メダカ / 始原生殖細胞 / 相周遺伝子組換え / シグナル伝達 / インターフェロンα / 慢性肝炎 / インターフェロン / B型肝炎 / 癌抑制院伝子 / 多段階発癌 / 肝炎 / 相同遺伝子組み換え / ウイルス発癌 … More
Except Principal Investigator
トランスジェニックマウス / ヒト疾患モデル / 生物機能モデル / ES細胞 / 細胞分化 / 発生 / 遺伝子導入 / モデル動物 / 実験動物 / 遺伝子トラッピング / 神経発生 / 細胞認識 / 形態形成 / 再生医学 / 遺伝子ターゲッティング / ジーンターゲッティング / 遺伝子治療 / 遺伝子解析 / 遺伝子マッピング / 系統情報 / 胚凍結保存 / 微生物特性検査 / 遺伝的特性検査 / リコンビナント・インブレッド系マウス / コンジェニック系マウス / 基準近交系マウス / 発生工学 / 遺伝子導入動物 / バイオサイエンス / Tsc-2 / 疾患モデル系統 / 動物モデル / 先天性代謝病 / 組織学 / 解剖学 / 細胞間相互作用 / 自己組織化 / 発生学 / 肝臓 / 遺伝子改変マウス / チペピジン / ドパミン / GIRKチャネル / 標的遺伝子組換え / 生殖系列 / ゼブラフィッシュ / 体外受精 / DNA導入動物 / 野生遺伝子導入動物 / トランスサイレチン / 遺伝子発現 / 細胞小器官異常 / 先天代謝異常 / ジ-ンタ-ゲッティング / 野生遺伝子 / 遺伝子操作 / 遺伝子標的導入法 / 家族性アミロイドポリニューロパチー / CRSIPR/Cas9 / CRISPR/Cas9 / 優性遺伝病 / コンデイショナルGIRK2KOマウス, / ケタミン / ドパミン D1 レセプター / アルツハイマー病 / 認知症改善作用 / GIRK2KOマウス / うつ病 / ドパミンD2 レセプター / 前頭皮質 / 5-HT7受容体 / 5-HT1A受容体 / 新奇物体認識試験 / 抗うつ様作用 / ドパミントランスポーター / ドパミンニューロン / 側坐核 / 腹側被蓋野 / tipepidine / antidepressant effect / dopamine neuron / ventral tegmental area / Knockout mouse / CRISPR/Cas system / GIRK2 subunit / GIRK channel / Ang gene human prealbumin gene / OTC gene / gene injection / in vitro fertilization / gene mapping / Gene cloning / 精巣化因子 / ^Aγ / プレアルブミン遺伝子 / Angiotensinogen遺伝子 / Ornithine・trans carvamirase遺伝子 / 成長ホルモン遺伝子 / ラットOTC遺伝子 / ラットAng´遺伝子 / ヒト成長ホルモン遺伝子 / βグロビン遺伝子 / ヒトAγ / 外来遺伝子の導入 / 精巣移植 / ヒトプレアルブミン遺伝子 / Ang'遺伝子 / OTC遺伝子 / 遺伝子注入 / 遺伝子のマッピング / 遺伝子のクローニング / germ lineage / embryo manipulation / mammalian / Germ cells / 哺乳類 / 生殖細胞 / Developmental biology / Regeneration biology / Regeneration medicine / Regeneration research / Organ regeneration / Regeneration / 発生生物学 / 再生生物学 / 再生研究 / 臓器再生 / 再生現象 / 遺伝子タ-デッティング / Cajal cell / gene trap method / EBV and gastric cancer / histone deacetylation / histone acetylation / dysregulation of cell cycle regulation / genomic stability / 将来検討会 / 留保金の使途 / 計画研究設定 / 総合がん総括班 / ワークショップ / 重点シンポジウム / 「発がん」領域 / 検討班 / 研究(2) / 研究(1) / 肝炎ウイルス検討会 / 進捗状況報告会 / シンポジウム / 計画研究 / 総括班会議 / 発がん感受性 / がん抑制遺伝子 / がん遺伝子 / ウイルス発がん / 放射線発がん / 化学発がん / がんの疫学 / 発がん / Cajal細胞 / 可変型遺伝子トラップ法 / EBVと発がん / ヒストン脱アセチル化 / ヒストンアセチル化 / 細胞周期制御の破綻 / ゲノム安定性 / In vitro fertilization of goat / Tissue-specific expression / Antisense growth hormone gene / Miniature livestock animals / Gene transfer / IGF-1レセプター遺伝子 / 矮性化遺伝子 / 遺伝子発現機構 / ニワトリIGF-1遺伝子 / ヤギ体外受精胚 / 臓器特異的発現 / 成長ホルモンアンチセンス遺伝子 / ミニチュア家畜 / 系統化システム / ミエリン塩基性タンパク質 / アミロイド沈着 / 挿入突然変異 / アンチセンスRNA / アンチセンスDNA / 8-クリスタリン遺伝子 / ヒトインターロイキン2 / 高血圧モデルマウス / アミロイドーシス / 疾患モデル / 情報 / 実験動物福祉 / ビデオプログラム / 教育訓練 / 形質転換性病態モデル動物 / 遺伝性疾患モデル動物作製 / 実験医学 / 形質転換動物 / グリセロール / グリセロール3-リン酸 / アミノ酸 / ピルビン酸ナトリウム / アスパラギン酸グルタミン酸ミトコンドリア膜輸送体 / 糖質毒性 / マウスモデル / シトリン欠損症 / 三次元 / 蛍光タンパク / 肝上皮 / 血管 / 組織発生 / HAC / BAC / 上皮 / RFP / GFP / イメージング / 組織形成 / 分子メカニズム / ノックアウト / 発生異常 / lacZ / ノックイン / ノックアウ / Sd変異マウス / 脊椎欠損 / 変異 ES 細胞 / 遺伝子破壊 / 脊索 / Ptf1a / transposon / Sd 変異マウス / Danforth's short tail / FGF / 肝類洞 / 上皮間充織相互作用 / 血管形成 / 組織構築 / FoxA2 / Tek / WT1 / TGF-beta / 発生分化 / 細胞組織 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 国際交流 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 国際研究者交流 / 若手支援 / 置換アレル / 相同組換え / アミロイド / レチノール結合タンパク / レチノール / ヒト化マウス / トランスサイレチン(TTR) / レチノール結合タンパク(RBP) / 分子遺伝学 / GIRK2コンデイショナルノックアウトマウス / GIRK2サブユニット / 難治性うつ病モデル / GIRK2コンデイショナルノックメアウトマウス / 排尿障害 / 難治性うつ病 / セロトニン / クロペラスチン / パーキンソン病 / 強迫性症候群 / NMR / 治療抵抗性うつ病 / 難治性脳疾患 / シナプス伝達 / 受容体 / 長期増強 / 海馬切片 / 海馬臓器培養組織 / 変異動物 / 記憶 / 学習 / GFAP / p53 / グルタミン酸受容体 / tau / myogenin / セロトニン受容体 / K-ras / N-ras / H-ras / ドーパミン受容体 / ジーンターゲッテイング / 標的遺伝子組替え / 遺伝子欠損マウス / ニワトリ / マウスゲノム / 標的組換え / 光受容 / 神経系 / 突然変異 / 神経系構築 / カイコ / セブラフィッシュ / 末梢神経 / 中枢神経 / ショウジョウバエ / ゼブラフィシュ / パターン形成 / シグナル伝達 / 分化決定 / 神経ネットワーク / 線虫 / モデル生物 / レセプター異常 / 凍結保存 / 遺伝子工学 / HTLVI / 遺伝子欠損モデル / 胚幹細胞 / 遺伝子診断 / 病因変異 / 遺伝子単離 / 分子生物学 / 単一遺伝子病 / レセプタ-異常 / ラボラトリ-マウス / 野生マウス / 高脂血症 / 高血圧 / キメラマウス / 標的遺伝子置換法 / ジ-ンタ-ゲッティング法 / 高血圧症モデル / 家族性アミロイドニュ-ロパシ- / 動物実験 / アンチセンス Less
  • Research Projects

    (79 results)
  • Research Products

    (180 results)
  • Co-Researchers

    (284 People)
  •  Gene therapy for FAP using TTR exon-humanized mouse

    • Principal Investigator
      Li Zhenghua
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48040:Medical biochemistry-related
    • Research Institution
      Kumamoto University
  •  Development of a revolutionary and inventive therapeutic drug for intractable brain diseases, targeting GIRK channel

    • Principal Investigator
      Kazuo Takahama
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pharmacology in pharmacy
    • Research Institution
      Kumamoto Health Science University
  •  To developtherapeutic and prophylactic procedures for citrin deficiency

    • Principal Investigator
      SAHEKI Takeyori
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kumamoto University
  •  Development of a mouse model for live-imaging of hepatic epithelial patterning in mouse embryonic liver using a HAC carrying BACs

    • Principal Investigator
      YOKOUCHI Yuji
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Kumamoto University
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, NAKAMURA Yuusuke
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Functional analysis of hepatic mesothelium-derived angiogenic factors in embryonic hepatic histogenesis

    • Principal Investigator
      YOKOUCHI Yuji
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Fukushima Medical University
      Kumamoto University
  •  Elucidation for molecular etiology of Danforth's short tail (Sd)mutant, a caudal regression model mouse

    • Principal Investigator
      SEMBA Kei
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Kumamoto University
  •  Genetic studies on unique phenotypes in MSM/Ms mouse strainPrincipal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      2009 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  MSM/Msマウスの疾患感受性・抵抗性に関する遺伝学的解析Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  Analysis pathologic processes of FAP development using double humanized mice

    • Principal Investigator
      RI Chuhoa
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Kumamoto University
  •  Study on development of novel drugs possessing therapeutic potentials for intractable brain diseases-aiming at GIRK channel as their molecular target

    • Principal Investigator
      TAKAHAMA Kazuo
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kumamoto University
  •  Integrated cancer research using in vivo modelsPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Frontier studies in development and cancerPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kumamoto University
  •  Analysis on genetic and environmental factors using a mouse model for dominantly inherited diseasePrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2005 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  生殖系列へ伝達されない遺伝子トラップアレルの解析Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Kumamoto University
  •  Develpment of a new method to revent amyloid formation in genetically engineered mice.Principal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Kumamoto University
  •  DEVELOPMENT OF MHV-RESISTANT MOUSE USING RNAi TRAP METHODPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  遺伝子変換マウス作製の技術開発及び発がん研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kumamoto University
  •  細菌人工染色体による相同組換えPrincipal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Human genetics
    • Research Institution
      Kumamoto University
  •  Regulative Mechanisms and Manipulation of the Germ Cell Lineage

    • Principal Investigator
      NAKATSUJI Norio
    • Project Period (FY)
      1999 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      KYOTO UNIVERSITY
  •  IDENTIFICATION OF DISEASE GENE USING BAC TRANSGENIC MICEPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Laboratory animal science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  Establishment of International Regeneration Research Network

    • Principal Investigator
      EGUCHI Goro
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      Kumamoto University
  •  DEVELOPMENT OF PREVENTION METHOD USING A MOUSE MODEL FOR FAMILIAL AMYLOIDOTIC POLYNEUROPATHYPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  標的遺伝子組換えによる生体機能の研究

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
      Kyushu University
  •  Identification of genes responsible for developmental mutant micePrincipal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Laboratory animal science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  DEVELOPEMNT OF TRANSGENIC TECHNOLOGY AND IT'S USE FOR CANCER RESEARCHPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  記憶・学習の分子機構

    • Principal Investigator
      宮本 英七
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kumamoto University
  •  IDENTIFICATION OF DEVELOPMENTAL CONTROL GENES USING YAC TRANSGENIC MICEPrincipal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  MOLECULAR MECAHNISMS OF ENDODERM DIFFERENTIATIONPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  PRODUCTION OF MUTANT MICE AND ESTABLISHMENT OF EMBRYO BANKPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  単一遺伝子病の分子・細胞生物学的研究

    • Principal Investigator
      多田 啓也, 勝木 元也
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
      Kyushu University
  •  Basic Research of carcinogenesis and cancer prevention (carcinogenesis)

    • Principal Investigator
      ITO Yoshiaki
    • Project Period (FY)
      1994 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Institute for Virus Research, Kyoto University
  •  癌化の遺伝要因の分子発生学的解析Principal Investigator

    • Principal Investigator
      ABE Kuniya, 山村 研一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  遺伝子導入動物による発症の研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  ES細胞を用いた未知遺伝子の検索Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  発生・形態形式の個体レベルにおける分子生物学的研究

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1993 – 1997
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Kyoto University
  •  発生・形態形成の個体レベルにおける分子生物学的研究

    • Principal Investigator
      竹市 雅敏
    • Project Period (FY)
      1993 – 1997
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Kyoto University
  •  発生・形態形成の個体レベルにおける分子生物学的研究

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1993 – 1997
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Kyoto University
  •  Production of transgenic livestock animals bearing antisense growth hormone cDNA and analysis of mechanisms of the transgene expression

    • Principal Investigator
      YAMADA Masayasu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Applied animal science
    • Research Institution
      KYOTO UNIVERSITY
  •  発生・形態形成の個体レベルにおける分子生物学的研究

    • Principal Investigator
      竹市 雅俊
    • Project Period (FY)
      1993 – 1997
    • Research Category
      Grant-in-Aid for Creative Basic Research
    • Research Institution
      Kyoto University
  •  遺伝子導入動物による発癌の研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  単一遺伝子病の分子・細胞生物学的研究、疾患発症の分子機構の解明

    • Principal Investigator
      松田 一郎
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  ショウジョウバエを用いた遺伝子機能解析

    • Principal Investigator
      西田 育巧 (西田 育功)
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
      Aichi Cancer Center Research Institute
  •  標的遺伝子組換えによる生体機能の研究

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Institution
      Kyushu University
  •  Production of mouse models for human diseases by gene targetingPrincipal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Molecular Embryology and Genetics Kumamoto University School of Medicine
  •  PRODUCTION OF MOUSE MODELS FOR MALFORMATION BY GENE TRAPPrincipal Investigator

    • Principal Investigator
      YAMAMURA Kenichi
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Laboratory animal science
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  遺伝子導入動物による発癌の研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  がん研究のための実験動物の維持と開発

    • Principal Investigator
      森脇 和郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      National Institute of Genetics
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  癌化の遺伝要因の分子発生学的解析Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  単一遺伝子病の分子・細胞生物学的研究,疾患発症の分子機構の解明

    • Principal Investigator
      松田 一郎
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  遺伝子導入動物による発癌の研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  癌化の遺伝要因の分子発生学的解析Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kumamoto University
  •  遺伝子導入動物による発癌の研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Transgenic mouseを用いた発癌の組織特異性に関する研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Analysis on the molecular mechanism of development using insertional mutant mice.Principal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Kumamoto University Medical School
  •  Transgenic mouseを用いた発癌の組織特異性に関する研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Molecular genetic analysis of familial amyloidotic polyneuropathyPrincipal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Human genetics
    • Research Institution
      KUMAMOTO UNIVERSITY
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987 – 1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  Transgenic mouseを用いた発癌の組織特異性に関する研究Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  バイオメディカルサイエンスの新展開に対応した動物実験施設での教育訓練のあり方

    • Principal Investigator
      濱岡 利之
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Osaka University
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  外来遺伝子DNA導入による新しいモデル動物の開発

    • Principal Investigator
      勝木 元也
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tokai University
  •  野生遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1987 – 1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Central Institute for Experimental Animals
  •  Gene cloning and gene manipulation for the succesful production of transgenic animal in farm animal

    • Principal Investigator
      IRITANI Akira
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      畜産学(含草地学)
    • Research Institution
      Kyoto University
  •  転座したMyc遺伝子のマウス受精卵への導入とリンパ腫発生機構の解析Principal Investigator

    • Principal Investigator
      山村 研一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  実験医学領域における形質転換動物の応用

    • Principal Investigator
      荻田 善一
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Toyama Medical and Pharmaceutical University
  •  野性遺伝子およびヒトDNA導入によるモデル動物の総合的開発システムの基礎的研究

    • Principal Investigator
      野村 達次
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      プラズマ理工学
    • Research Institution
      Central Institute for Experimental Animals
  •  Production of a transgenic mouse model of familial amyloidotic polyneuropathy.Principal Investigator

    • Principal Investigator
      YAMAMURA Ken-ichi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human genetics
    • Research Institution
      Kumamoto University Medical School
  •  先天性代謝病動物モデルによる病因の解析と治療に関する研究

    • Principal Investigator
      近藤 恭司
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Nagoya University
  •  先天性代謝病動物モデルによる病因の解析と治療に関する研究

    • Principal Investigator
      近藤 恭司
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Nagoya University

All 2022 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book Patent Other

  • [Book] Genetic manipulations using Cre and mutant loxP sites. (ed. Alexei Morozov), in Controlled genetic manipulations.2012

    • Author(s)
      Araki, K. and Yamamura, K.
    • Total Pages
      17
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Book] Genetic manipulations using Cre and mutant loxP sites. (ed. Alexei Morozov), in Controlled genetic manipulations. Neuromethods. Vol 652012

    • Author(s)
      Araki, K. and Yamamura, K.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Book] 論文ができてしまう!疾患モデルマウス表現型解析指南2011

    • Author(s)
      編集:山村研一/若菜茂晴
    • Total Pages
      464
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Book] 疾患モデルマウス表現型解析指南2011

    • Author(s)
      山村研一、若菜茂晴, 編
    • Total Pages
      477
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Book] Genetic manipulations using Cre and mutant loxP sites. (ed. Alexei Morozov), in Controlled genetic manipulations2009

    • Author(s)
      Araki, K. and Yamamura, K
    • Publisher
      Neuromethods
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Book] 再生医療(学問領域としての「発生医学」の曙光期-日本における発生工学の黎明と「発生医学」への展開)2009

    • Author(s)
      山村研一
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Book] 最新医学(ES細胞研究の歴史, 増刊号)2009

    • Author(s)
      山村研一
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Dissecting pathophysiology of a human dominantly inherited disease, familial amyloidotic polyneuropathy, by using genetically engineered mice.2022

    • Author(s)
      Li Z, Yamamura K.
    • Journal Title

      Frigid Zone Med

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07354
  • [Journal Article] TTR exon-humanized mouse optimal for verifying new therapies for FAP2022

    • Author(s)
      Li Z, Kanazashi H, Tokashiki Y, Fujikawa R, Okagaki A, Katoh S, Kojima K, Haruna K, Matsushita N, Ishikawa TO, Chen H, Yamamura K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 599 Pages: 6974-6974

    • DOI

      10.1016/j.bbrc.2022.02.035

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07354
  • [Journal Article] Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice2018

    • Author(s)
      Ikutaro Honda, Kimi Araki, Sokich Honda, Fumio Soeda, Min-Chul Shin, Shogo Misumi, Ken-ichi Yamamura, Kazuo Takahama
    • Journal Title

      Neuroscience Letters

      Volume: 665 Pages: 140-146

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Journal Article] Cathepsin D in pancreatic acinar cells is implicated in cathepsin B and L degradation, but not in autophagic activity.2016

    • Author(s)
      Mehanna, S, Suzuki, C., Shibata, M., Sunabori, T., Imanaka, T., Araki, K., Yamamura, K., Uchiyama, Y. and Ohmuraya, M.
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 469 Issue: 3 Pages: 405-411

    • DOI

      10.1016/j.bbrc.2015.12.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-26860139, KAKENHI-PROJECT-16K07093
  • [Journal Article] Severe ocular phenotypes in Rbp4-deficient mice in the C57BL/6 genetic background.2016

    • Author(s)
      Shen, J., Shi, D., Suzuki, T., Xia, Z., Zhang, H., Araki, K., Wakana, S., Takeda, N., Yamamura, K., Jin, S. and Li. Z.
    • Journal Title

      Lab. Invest.

      Volume: in press Issue: 6 Pages: 1-12

    • DOI

      10.1038/labinvest.2016.39

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-16K07093
  • [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation 1 during cochlear, enteric, and skeletal development: possible role in convergent extension.2015

    • Author(s)
      Akiko Iizuka-Kogo, Takao Senda, Tetsu Akiyama, Atsushi Shimomura, Ryuji Nomura, Yoshimi Hasegawa, Ken-ichi Yamamura, Hiroshi Kogo, Nobuhiko Sawai, Toshiyuki Matsuzaki
    • Journal Title

      PLoS ONE

      Volume: 10 Issue: 4 Pages: e0123965-e0123965

    • DOI

      10.1371/journal.pone.0123965

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24590263, KAKENHI-PROJECT-24592567, KAKENHI-PROJECT-25460240, KAKENHI-PROJECT-221S0001
  • [Journal Article] Schwann cells contribute to neurodegeneration of transthyretin amyloidosis2015

    • Author(s)
      Murakami, T., Sango, K., Watabe, K., Niimi, N., Takaku, S., Li, Z, Yamamura, K., Sunada, Y.
    • Journal Title

      J. Neurochem

      Volume: 134 Issue: 1 Pages: 66-74

    • DOI

      10.1111/jnc.13068

    • Description
      in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06763, KAKENHI-PROJECT-24500428, KAKENHI-PROJECT-25430056
  • [Journal Article] Mechanism for increased hepatic glycerol synthesis in the citrin/mitochondria glycerol-3-phosphate dehydrogenase double-knockout mouse: Urine glycerol and glycerol 3-phosphate as potential diagnostic markers of human citrin deficiency.2015

    • Author(s)
      Moriyama M, Fujimoto Y, Rikimaru S,Ushikai M, Kuroda E, Kawabe K, Takano K,Asakawa A, Inui A, Eto K, Kadowaki T, Sinasac DS, Okano Y, Yazaki M, Ikeda SI,Zhang C, Song YZ,Sakamoto O, Kure S, Mitsubuchi H, Endo F, Horiuchi M, Nakamura Y, Yamamura KI, Saheki T.
    • Journal Title

      Biochim Biophys Acta.

      Volume: 印刷中 Issue: 9 Pages: 1787-1795

    • DOI

      10.1016/j.bbadis.2015.04.023

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24590892, KAKENHI-PROJECT-15K07768, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15J12259, KAKENHI-PROJECT-25461275, KAKENHI-PROJECT-26850209, KAKENHI-PROJECT-26000012
  • [Journal Article] CHF5074 (CSP-1103) stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci.2015

    • Author(s)
      Mu, Yanshuang; Jin, Shoude; Shen, Jingling; Sugano, Aki; Takaoka, Yutaka; Qiang, Lixia; Imbimbo, Bruno P; Yamamura, Ken-Ichi; Li, Zhenghua
    • Journal Title

      FEBS Letters

      Volume: 589 Issue: 7 Pages: 849-856

    • DOI

      10.1016/j.febslet.2015.02.020

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590404, KAKENHI-PROJECT-221S0001
  • [Journal Article] Roles of hepatic glucokinase in intertissue metabolic communication: examination of novel liver-specific glucokinase knockout mice2015

    • Author(s)
      Hayashi H
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 印刷中 Issue: 3 Pages: 727-732

    • DOI

      10.1016/j.bbrc.2015.03.097

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-221S0001
  • [Journal Article] Transgenic mouse model for imaging of interleukin-1β-related inflammation in vivo.2015

    • Author(s)
      Iwawaki T, Akai R, Oikawa D, Toyoshima T, Yoshino M, Suzuki M, Takeda N, Ishikawa T, Kataoka Y, Yamamura K.
    • Journal Title

      Scientific Reports.

      Volume: 5 Issue: 1 Pages: 17205-17205

    • DOI

      10.1038/srep17205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08259, KAKENHI-PUBLICLY-15H00905, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25460399
  • [Journal Article] Requirement of DLG1 for cardiovascular development and tissue elongation during cochlear, enteric, and skeletal development : possible role in convergent extension2015

    • Author(s)
      Iizuka-Kogo, A., Senda, T., Akiyama, T., Shimomura, A., Nomura, R., Hasegawa, Y., Yamamura, K., Kogo, H., Sawai, N. and Matsuzaki, T.
    • Journal Title

      Plos One

    • Description
      in press
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] SPINK1 Status in Colorectal Cancer, Impact on Proliferation, and Role in Colitis-associated Cancer.2015

    • Author(s)
      Ida S, Ozaki N, Araki K, Hirashima K, Zaitsu Y, Taki K, Sakamoto Y, Miyamoto Y, Oki E, Morita M, Watanabe M, Maehara Y, Yamamura KI, Baba H Professor, Ohmuraya M.
    • Journal Title

      Molecular Cancer Research

      Volume: - Issue: 7 Pages: 1130-8

    • DOI

      10.1158/1541-7786.mcr-14-0581

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25861196, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-25462029, KAKENHI-PROJECT-25640052
  • [Journal Article] Incidence, serum IgE and TARC/CCL17 levels of atopic dermatitis in association with other related allergic diseases: An update from the Ishigaki Island cohort.2015

    • Author(s)
      Takeuchi S, Esaki H, Furusyo N, Hayashida S, Yamamura K, Tsuji G, Takemura M, Hayashi J, Furue M:
    • Journal Title

      Acta Dermato Venereologica

      Volume: 95 Issue: 4 Pages: 480-484

    • DOI

      10.2340/00015555-1989

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY32014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K
    • Journal Title

      J. Diabetes Invest

      Volume: (in press) Pages: 407-423

    • DOI

      10.1016/b978-0-12-800174-5.00016-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-25293212
  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2014

    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63

    • NAID

      130003391605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] mTORC1 controls the cell cycle of the earliest T-lineage-committed cells and its inactivation eradicates acute lymphoblastic T-cell leukemia in mice.2014

    • Author(s)
      Hoshii, T., Kasada, A., Hatakeyama, N., Ohtani,M., Tadokoro, Y., Naka, K., Ikenoue, T., Ikawa, T., Kawamoto, H., Araki, K., Yamamura, K., Matsuda, S. and Hirao, A.
    • Journal Title

      Proc. Natl. Acad. Sci. USA.

      Volume: in press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY32014

    • Author(s)
      Ohki, T,, Utsu, Y., Morita, S., Karim, M.F., Sato, Y., Yoshizawa, T., Yamamura, K., Yamada, K., Kasayama, S., Yamagata, K.
    • Journal Title

      Journal of Diabetes Investigation

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim MF, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
    • Journal Title

      Journal of Diabetes Investigation

      Volume: in press Issue: 5 Pages: 513-516

    • DOI

      10.1111/jdi.12237

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-221S0001
  • [Journal Article] Genetic analysis of the role of Alx4 in the coordination of lower body and external genitalia formation,2014

    • Author(s)
      Daisuke Matsumaru, Ryuma Haraguchi, Anne M. Moon, Yoshihiko Satoh, Naomi Nakagata, Ken-ichi Yamamur, Naoki Takahashi, Sohei Kitazawa, Gen Yamada.
    • Journal Title

      Eur J Hum Genet

      Volume: 22(3) Issue: 3 Pages: 350-357

    • DOI

      10.1038/ejhg.2013.160

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-23659186, KAKENHI-PROJECT-24790292, KAKENHI-PROJECT-25860143, KAKENHI-PROJECT-221S0001
  • [Journal Article] New Insight into Reactive Ductular Cells of Biliary Atresia Provided by Pathological Assessment of SOX92014

    • Author(s)
      Hiroko Suda, Daiki Yoshii, Kenichi Yamamura, Yuji Yokouchi, Yukihiro Inomata
    • Journal Title

      Pediatric Surgery International

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390034
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling.2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K., and Ohmuraya, M.
    • Journal Title

      Biochem. Biophysic. Res. Comm.

      Volume: in press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Autophagy regulation in the pancreatic acinar cells is independent of epidermal growth factor receptor signaling.2014

    • Author(s)
      Ozaki, N., Fukuchi, Y., Tomiyoshi, S., Uehara1, H., Ida, S., Wang, J., Kimi Araki, K., Sibilia, M., Baba, H., and Yamamura, K. and Ohmuraya, M.
    • Journal Title

      Biochem. Biophysic. Res. Comm.

      Volume: 446 Issue: 1 Pages: 224-230

    • DOI

      10.1016/j.bbrc.2014.02.111

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-23310135, KAKENHI-PUBLICLY-24115712, KAKENHI-PROJECT-24591016, KAKENHI-PROJECT-25640052, KAKENHI-PROJECT-25861196, KAKENHI-PLANNED-26110003, KAKENHI-PUBLICLY-26111516, KAKENHI-PROJECT-221S0001
  • [Journal Article] Disruption of actin-binding domain-containing Dystonin protein causes dystonia musculorum in mice.2014

    • Author(s)
      Horie, M., Watanabe, K., Bepari, A. K., Nashimoto, J., Araki, K., Sano, H., Chiken, S., Nambu, A., Ono, K., Ikenaka, K., Kakita, A., Yamamura, K. and Takebayashi, H.
    • Journal Title

      Eur. J Neurosci.

      Volume: 40 Issue: 10 Pages: 3458-3471

    • DOI

      10.1111/ejn.12711

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23590237, KAKENHI-PROJECT-24700351, KAKENHI-PLANNED-25117007, KAKENHI-PROJECT-25351002, KAKENHI-PROJECT-26430021, KAKENHI-PROJECT-221S0001
  • [Journal Article] Database for exchangeable gene trap clones: Pathway and gene ontology analysis of exchangeable gene trap clone mouse lines.2014

    • Author(s)
      Araki, M., Nakahara, M., Muta, M., Itou, M., Yanai, C., Yamazoe, F., Miyake, M., Morita, A., Araki, M., Okamoto, Y., Nakagata, M., Yoshinobu, K., Yamamura, K. and Araki, K.
    • Journal Title

      Develop. Growth Differ.

      Volume: 56 Issue: 2 Pages: 161-174

    • DOI

      10.1111/dgd.12116

    • NAID

      40019987325

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-25430092, KAKENHI-PROJECT-221S0001
  • [Journal Article] Low serum level of high-sensitivity C-reactive protein in a Japanese subject with MODY3.2014

    • Author(s)
      Ohki T, Utsu Y, Morita S, Karim M.F., Sato Y, Yoshizawa T, Yamamura K, Yamada K, Kasayama S, Yamagata K.
    • Journal Title

      J. Diabetes Invest.

      Volume: in press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation2014

    • Author(s)
      Maehara N, Arai S, Mori M, Iwamura Y, Kurokawa J, Kai T, Kusunoki S, Taniguchi K, Ikeda K, Ohara O, Yamamura K, Miyazaki T
    • Journal Title

      Cell Reports

      Volume: 9 Issue: 1 Pages: 61-74

    • DOI

      10.1016/j.celrep.2014.08.058

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-26861314, KAKENHI-PROJECT-221S0001
  • [Journal Article] Circulating AIM as an Indicator of Liver Damage and Hepatocellular Carcinoma in Humans2014

    • Author(s)
      Yamazaki T, Mori M, Arai S, Tateishi R, Abe M, Ban M, Nishijima A, Maeda M, Asano T, Kai T, Izumino K, Takahashi J, Aoyama K, Harada S, Takebayashi T, Gunji T, Ohnishi S, Seto S, Yoshida Y, Hiasa Y, Koike K, Yamamura K, Inoue K, Miyazaki T
    • Journal Title

      PLOS ONE

      Volume: 9 Issue: 10 Pages: e109123-e109123

    • DOI

      10.1371/journal.pone.0109123

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-25253056, KAKENHI-PROJECT-26861314, KAKENHI-PROJECT-221S0001
  • [Journal Article] Obesity-associated autoantibody production requires AIM to retain IgM immune complex on follicular dendritic cells2013

    • Author(s)
      Arai, S., et al.
    • Journal Title

      Cell Rep.

      Volume: 3 Issue: 4 Pages: 1-12

    • DOI

      10.1016/j.celrep.2013.03.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J05522, KAKENHI-PROJECT-23390091, KAKENHI-PROJECT-23791107, KAKENHI-PROJECT-24249021, KAKENHI-PROJECT-24390196, KAKENHI-PROJECT-24659175, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-221S0001
  • [Journal Article] Multi-modal effects of BMP signaling on Nodal expression in the lateral plate mesoderm during left-right axis formation in the chick embryo2013

    • Author(s)
      Kenjiro Katsu, Norifumi Tatsumi, Daisuke Niki, Ken-ichi Yamamura, Yuji Yokouchi
    • Journal Title

      Developmental Biology

      Volume: 374 Issue: 1 Pages: 71-84

    • DOI

      10.1016/j.ydbio.2012.11.027

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390034, KAKENHI-PROJECT-22590176, KAKENHI-PROJECT-24790197
  • [Journal Article] Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice2013

    • Author(s)
      Nakahara, M., Tateyama, H., Araki, M., Nakagata, N., Yamamura, K. and Araki, K.
    • Journal Title

      Mammal Genome

      Volume: 24 Issue: 5-6 Pages: 228-239

    • DOI

      10.1007/s00335-013-9452-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-23310135, KAKENHI-PUBLICLY-24115712, KAKENHI-PROJECT-221S0001
  • [Journal Article] Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.2013

    • Author(s)
      Hoshii T, Kasada A, Hatakeyama T, Ohtani M, Tadokoro Y, Naka K, Ikenoue T, Ikawa T, Kawamoto H, Fehling HJ, Araki K, Yamamura K, Matsuda S, Hirao A
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 111 Issue: 10 Pages: 3805-3810

    • DOI

      10.1073/pnas.1320265111

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22118004, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-24240119, KAKENHI-PROJECT-24249057, KAKENHI-PROJECT-24689042, KAKENHI-PROJECT-24790967, KAKENHI-PUBLICLY-25118710, KAKENHI-PUBLICLY-25118732, KAKENHI-PUBLICLY-25130705, KAKENHI-PROJECT-25460602, KAKENHI-PROJECT-25461411, KAKENHI-PROJECT-25670236, KAKENHI-PROJECT-25670447, KAKENHI-PROJECT-221S0001
  • [Journal Article] PAD4 regulates proliferation of multipotent hematopoietic cells by controlling c-myc expression.2013

    • Author(s)
      Nakashima K, Arai1 S, Suzuki A, Nariai Y, Urano T, Nakayama M, Ohara O, Yamamura K, Yamamoto K, Miyazaki T.
    • Journal Title

      Nature Communications.

      Volume: 4 Issue: 1 Pages: 1836-1836

    • DOI

      10.1038/ncomms2862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23229007, KAKENHI-PROJECT-23791107, KAKENHI-PROJECT-25461494, KAKENHI-PROJECT-221S0001
  • [Journal Article] Generation and analysis of serine protease inhibitor Kazal type 3-cre driver mice2013

    • Author(s)
      Sakata, K., Ohmuraya, M., Araki, K., Suzuki, C., Ida, S., Hashimoto, D., Wang, J., Uchiyama, Y., Baba, H. and Yamamura, K.
    • Journal Title

      Exp. Anim.

      Volume: 63 Pages: 45-53

    • NAID

      130003391605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Multi-modal effects of BMP signaling on Nodal expression in the lateral plate mesoderm during left-right axis formation in the chick embryo2013

    • Author(s)
      Kenjiro Katsu, Norifumi Tatsumi, Daisuke Niki, Ken-ichi Yamamura, Yuji Yokouchi
    • Journal Title

      Developmental Biology

      Volume: 374 Pages: 71-84

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23659097
  • [Journal Article] Role of intrapancreatic SPINK1/Spink3 expression in the development of pancreatitis2012

    • Author(s)
      Ohmuraya, M., Sugano, A., Hirota, M., Takaoka, Y. and Yamamura, K
    • Journal Title

      Frontiers in Physiol

      Volume: 3

    • DOI

      10.3389/fphys.2012.00126

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24591016, KAKENHI-PROJECT-221S0001
  • [Journal Article] Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells2012

    • Author(s)
      Ohki T, Sato Y, Yoshizawa T, Yamamura K, Yamada K, Yamagata K
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 425 Issue: 3 Pages: 619-624

    • DOI

      10.1016/j.bbrc.2012.07.134

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24790932, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-23126521
  • [Journal Article] A Cre Knock-in Mouse Line on the Sickle Tail Locus Induces Recombination in the Notochord and Intervertebral Discs.2012

    • Author(s)
      Abe, K. et al.
    • Journal Title

      Genesis

      Volume: 50 Issue: 10 Pages: 758-765

    • DOI

      10.1002/dvg.22035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-22500392, KAKENHI-PROJECT-22791388, KAKENHI-PROJECT-23300159, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-24592213, KAKENHI-PROJECT-221S0001, KAKENHI-PUBLICLY-24115712
  • [Journal Article] Ectopic expression of Ptf1a induces spinal defects, urogenital defects and anorectal malformations in Danforth's short tail mice.2012

    • Author(s)
      Semba, K., Araki, K., Matsumoto, K.-I., Suda, H., Ando, T. Sei, A., Mizuta, H., Takagi, K., Nakahara, M., Muta, M., Yamada, G., Nakagata, N., Iida, A., Ikegawa, Y., Araki, M., Abe, K. and Yamamura, K.
    • Journal Title

      PLoS Genet.

      Volume: Vol.9 Issue: 2 Pages: 1-17

    • DOI

      10.1371/journal.pgen.1003204

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-20062013, KAKENHI-PROJECT-21220010, KAKENHI-PLANNED-22132006, KAKENHI-PROJECT-22791388, KAKENHI-PROJECT-23300159, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23651189, KAKENHI-PUBLICLY-24115712, KAKENHI-PROJECT-25670653, KAKENHI-PROJECT-221S0001
  • [Journal Article] Enhanced expression of human cDNA by phosphoglycerate kinase promoter-puromycin cassette in the mouse transthyretin locus2011

    • Author(s)
      Zhenghua Li, Gang Zhao, Jingling Shen, Kimi Araki, Kyoko Haruna, Seiya Inoue, Jun Wang, Ken-ichi Yamamura
    • Journal Title

      Transgenic Research

      Volume: Vol.20 Pages: 191-200

    • URL

      http://dx.doi.org/10.1007/s11248-010-9389-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Journal Article] Transgenic expression of pancreatic secretory trypsin inhibitor-1 rescues SPINK3 deficient mice and restores a normal pancreatic phenotype2010

    • Author(s)
      Romac, J., M. Ohmuraya, M., C. Bittner, C., Majeed, M. F., Vigna, S. R., Que, J., Fee, B. E., Wartmann, T., Yamamura, K. and Liddle, R. A
    • Journal Title

      Amer. J. Physiol

      Volume: 298 Issue: 4 Pages: G518-G524

    • DOI

      10.1152/ajpgi.00431.2009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] The transthyretin gene is expressed in Schwann cells of peripheral nerves2010

    • Author(s)
      Tatsufumi Murakami, Yutaka Ohsawa, Li Zhenghua, Ken-ichi Yamamura, Yoshihide Sunada
    • Journal Title

      Brain research

      Volume: Vol.1248 Pages: 222-225

    • URL

      http://dx.doi.org/10.1016/j.brainres.2010.06.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Journal Article] Relationship of strain-dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression2010

    • Author(s)
      Wang, J., Ohmuraya, M., Suyama, K., Hirota, M., Ozaki, N., Baba, H., Nakagata, N., Araki, K. and Yamamura, K
    • Journal Title

      Lab. Invest

      Volume: 90 Issue: 5 Pages: 654-64

    • DOI

      10.1038/labinvest.2010.44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Effect of low-molecular-weight trypsin inhibitor, nafamostat mesilate, on trypsin activity using the pancreatic acinar cells2009

    • Author(s)
      Hashimoto, D., Ohmuraya, M., Hirota, M., Wang, J., Baba, H. and Yamamura, K
    • Journal Title

      Pancreas

      Volume: 38 Issue: 5 Pages: 595-597

    • DOI

      10.1097/mpa.0b013e31819156de

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Serine protease inhibitor, Kazal type 1, promotes proliferation of pancreatic cancer cells through the epidermal growth factor receptor.2009

    • Author(s)
      Ozaki, N., Ohmuraya, M., Hirota, M., Ida, S., Wang, J., Takamori, H., Higashiyama, S., Baba, H., Yamamura, K.
    • Journal Title

      Mol. Cancer Res 7巻

      Pages: 1572-1581

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] International gene trap project : Towards gene-driven saturation mutagenesis in mice2009

    • Author(s)
      Araki, M., Araki, K. and Yamamura, K.
    • Journal Title

      Current Pharmaceutical Biothechnology 10

      Pages: 221-229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Journal Article] Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain.2009

    • Author(s)
      Araki, K., Takeda, T., Yoshiki, A., Obata, Y., Nakagata, N., Shiroishi, T., Moriwaki, K., Yamamura, K.
    • Journal Title

      Mammal. Genome 20巻

      Pages: 14-20

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Establishment of germline-competent embryonic stem cell lines from the MSM/Ms strain2009

    • Author(s)
      Araki, K., Takeda, N., Yoshiki, A., Obata, Y., Nakagata, N., Shiroishi, T., Moriwaki, K. and Yamamura, K
    • Journal Title

      Mamm Genome

      Volume: 20 Issue: 1 Pages: 14-20

    • DOI

      10.1007/s00335-008-9160-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Journal Article] Defective development of the gall bladder and cystic duct in Lgr4-hypomorphic mice.2009

    • Author(s)
      Yamashita, R., Takegawa, Y., Sakumoto, M., Nakahara, M., Kawazu, H., Hoshii, T., Araki, K., Yokouchi, Y., Yamamura, K.
    • Journal Title

      Mechanism Dev 238巻

      Pages: 993-1000

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Gene trap mutagenesis in mice: New perspectives and tools in cancer research.2008

    • Author(s)
      Yamamura, K., Araki, K.
    • Journal Title

      Cancer Sci Vol.99

      Pages: 40549-40549

    • NAID

      10024000620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Journal Article] Gene trap mutagenesis in mice; New perspectives and tools in cancer research.2008

    • Author(s)
      Yamamura, K., et. al.
    • Journal Title

      Cancer Science. 99

      Pages: 1-6

    • NAID

      10024000620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Gene trap mutagenesis in mice; New perspectives and tools in cancer research.2008

    • Author(s)
      Yamamura, K., et. al.
    • Journal Title

      Cancer Science. 99

      Pages: 1-6

    • NAID

      10024000620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Journal Article] Gene trap mutagenesis in mice ; New perspectives and tools in cancer research2008

    • Author(s)
      Yamamura, K., et.al.
    • Journal Title

      Cancer Science 99

      Pages: 1-6

    • NAID

      10024000620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Cranial bone morphometric study among mouse strains2008

    • Author(s)
      Kawakami, M. and Yamamura, K.
    • Journal Title

      BMC(BioMed Central)Evolutionary Biol 8

      Pages: 73-83

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Journal Article] Involvement of autophagy in trypsinogen activation.2008

    • Author(s)
      Hashimoto, D., Ohmuraya, M., Hirota, M., Yamamoto, A., Suyama, K., Baba, H., Araki, K., Mizushima, N., Yamamura, K.
    • Journal Title

      J. Cell Biol. 181巻

      Pages: 1065-1072

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Elevated expression of human・ABHD2 gene in mature macrophage in vulnerable plaques. Biochem.2008

    • Author(s)
      Miyata, K., Nakayama, M., Mizuta, S., Hokimoto, S., Sugamura, K., Oshima, S., Oike, Y., Sugiyama, S., Ogawa, H., Yamamura, K.
    • Journal Title

      Biophys. Res. Commun. 365巻

      Pages: 207-213

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Gene trap mutagenesis in mice ; New perspectives and tools in cancer research2008

    • Author(s)
      Yamamura, K. and Araki, K.
    • Journal Title

      Cancer Science 99

      Pages: 1-6

    • NAID

      10024000620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Journal Article] Autophagy and acute pancreatitis : A novel autophagy theory for trypsinogen activ ation2008

    • Author(s)
      Ohmuraya, M. and Yamamura, K.
    • Journal Title

      Autophagy 4

      Pages: 1060-1062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] LGR4 regulates the postnatal development and integrity of male reproductive tracts in mice.2007

    • Author(s)
      Hoshii, T., Takeo, T., Nakagata, N., Takeya, M., Araki, K., Yamamura, K.
    • Journal Title

      Biol. Reprod. 76巻

      Pages: 303-313

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Enhanced trypsin activity in pancreatic acinar cells deficient for serine protease inhibitor Kazal type 3.2006

    • Author(s)
      Ohmuraya, M., Hirota, M., Araki, K., Baba, H., Yamamura, K.
    • Journal Title

      Pancreas 33巻

      Pages: 104-106

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] A novel murine gene, Sickle tail (Skt), linked to the Danforth's short tail (Sd) locus, is required for normal development of the intervertebral disc.2006

    • Author(s)
      Semba, K., Araki, K., Li, Z., Matsumoto, K., Suzuki, M., Nakagata, N., Takagi, K., Takeya, M., Yoshinobu, K., Araki, M., Imai, K., Abe, K., Yamamura, K.
    • Journal Title

      Genetics 172巻

      Pages: 445-456

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Negative Selection with the Diphtheria toxin A fragment Gene Improves Frequency of Cre-Mediated Cassette Exchange in ES Cells2006

    • Author(s)
      Araki, K., Araki, M. and Yamamura, K.
    • Journal Title

      J. Biochem. 140

      Pages: 793-798

    • NAID

      10018840450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Journal Article] Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the abhydrolase domain containing 2 gene.2005

    • Author(s)
      Miyata, K, Oike, Y, Hoshii, T, Maekawa, H, Ogawa, H, Suda, T, Araki, K, Yamamura, K.
    • Journal Title

      Biochem Biophys Res Commun 329巻

      Pages: 296-304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Journal Article] Autophagic cell death of pancreatic acinar cells in serine protease inhibitor Kazal Type 3 deficient mice.2005

    • Author(s)
      Ohmuraya, M., Hirota, M., Araki, M., Mizushima, N., Matsui, M., Mizumoto, T., Haruna, K., Kume, S., Takeya, M., Ogawa, M., Araki, K., Yamamura, K.
    • Journal Title

      Gastroenterology 129巻

      Pages: 696-705

    • Data Source
      KAKENHI-PROJECT-17012018
  • [Patent] トラップベクター及びこれを用いた遺伝子トラップ法2011

    • Inventor(s)
      山村研一, 荒木喜美
    • Industrial Property Rights Holder
      トランスジェニック社
    • Acquisition Date
      2011-02-25
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Patent] トラップベクター及びこれを用いた遺伝子トラップ法2010

    • Inventor(s)
      山村研一, 荒木喜美
    • Industrial Property Rights Holder
      トランスジェニック社
    • Acquisition Date
      2010-05-26
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Patent] トラップベクター及びこれを用いた遺伝子トラップ法2010

    • Inventor(s)
      山村研一 荒木喜美
    • Industrial Property Rights Holder
      トランスジエニック社
    • Acquisition Date
      2010-03-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Patent] トラップベクターおよびこれを用いた遺伝子トラップ法2010

    • Inventor(s)
      山村研一、荒木喜美
    • Industrial Property Rights Holder
      株式会社トランスジェニック
    • Filing Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Patent] トラップベクター及びこれを用いた遺伝子トラップ法2010

    • Inventor(s)
      山村研一 荒木喜美
    • Industrial Property Rights Holder
      トランスジェニック社
    • Acquisition Date
      2010-03-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Patent] トラップベクターおよびこれを用いた遺伝子トラップ法2010

    • Inventor(s)
      山村研一、荒木喜美
    • Industrial Property Rights Holder
      株式会社トランスジェニック
    • Filing Date
      2010-03-10
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Patent] 特許権2007

    • Inventor(s)
      山村研一荒木喜美
    • Industrial Property Rights Holder
      トランスジエニツク社
    • Filing Date
      2007-12-25
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Patent] トラップベクターおよびこれを用いた遺伝子トラップ法2007

    • Inventor(s)
      山村研一、荒木喜美
    • Industrial Property Rights Holder
      株式会社トランスジェニック
    • Filing Date
      2007-12-25
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Patent] トラップベクターおよびこれを用いた遺伝子トラップ法

    • Inventor(s)
      山村研一、荒木喜美
    • Industrial Property Rights Holder
      株式会社トランスジェニック
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] エクソンヒト化による治療法開発に最適なFAPモデルマウスの開2020

    • Author(s)
      李正花、金指英樹、加藤洋教、渡嘉敷佳美、藤川理恵、岡垣郁香、加藤翔、小島健太、春名享子、松下直子、熊ノ郷晴子、品川真吾、石川智夫、山村研一
    • Organizer
      日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K07354
  • [Presentation] チペピジンの新奇抗うつ様効果発現における脳内ドパミン系の関与:GIRK2サブユニット欠損マウスでの検討2018

    • Author(s)
      本多 幾多郎、荒木 喜美、申 敏哲、土井 篤、山村 研一、三隅 将吾、高濱 和夫
    • Organizer
      学会 第138年会
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] ドパミントランスポーター発現ニューロンにおけるGIRK2サブユニット欠損の電気生理学的解析2017

    • Author(s)
      本多 幾多郎、申 敏哲、土井 篤、荒木 喜美、山村 研一、三隅 将吾、高濱 和夫
    • Organizer
      第74回 日本神経精神薬理学会
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] GIRK2コンデイショナルKOマウスの作製とそのうつ様行動の解析:うつ様行動としての無動におけるGIRK2チャネルの役割2016

    • Author(s)
      本多 幾多郎、荒木 喜美、野口 茂、笹岡 俊邦、本田 宗吉、高橋 大貴、副田 二三夫、三隅 将吾、山村 研一、高濱 和夫
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] GIRK2コンデイショナルKOマウスの作成とそのうつ様行動の解析:うつ様行動としての無動におけるGIRK2チャネルの役割2016

    • Author(s)
      本多幾多郎、荒木喜美、本田宗吉、高橋大貴、副田二三夫、三隅将吾、山村研一、高濱和夫
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 遺伝学と実験動物学2016

    • Author(s)
      山村研一
    • Organizer
      筑波大学生命科学動物資源センターシンポジウム
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2016-03-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 遺伝子トラップマウスを用いたlincRNAの生体内機能解析2015

    • Author(s)
      荒木正健、中原舞、柳井千佳、山添史雅、宮家幹子、森田彩香、岡本頼幸、荒木美幸、伊東春香、山村研一、吉信公美子、荒木喜美
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] マウスを用いた疾患遺伝学の展開2015

    • Author(s)
      山村研一
    • Organizer
      奈良医大特別講演
    • Place of Presentation
      奈良県立医大厳橿会館(奈良県橿原市)
    • Year and Date
      2015-10-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 遺伝子改変慢性膵炎モデルマウスではオートファジー不全とネクロプトーシスが誘導される2015

    • Author(s)
      大村谷昌樹、荒木喜美、山村研一
    • Organizer
      第62回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] マウス肝組織発生中の肝芽細胞におけるTGF-betaシグナリング経路の機能2015

    • Author(s)
      横内裕二,竹田直樹,佐々木洋,山村研一,竹之下誠一
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] CHF5074 (CSP-1103)はTtrおよびRbp遺伝子座のダブルヒトマウスの血中ヒトTTR 4量体を安定化する2015

    • Author(s)
      李正花,荒木喜美,山村研一
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Danforth's short tail (Sd) 変異はトランスポゾン挿入によって引き起こされたPtf1a 遺伝子の異所性発現が原因である2015

    • Author(s)
      荒木喜美、仙波 圭、中原舞、阿部訓也、荒木正健、山村研一
    • Organizer
      日本遺伝学会第87回大会
    • Place of Presentation
      東北大学川内北キャンパス(宮城県仙台市)
    • Year and Date
      2015-09-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Humanized mice as tools for personalized medicine2015

    • Author(s)
      Kenichi Yamamura
    • Organizer
      Gene-editing transgenics & stem cells
    • Place of Presentation
      Trinity Biomedical Sciences Institute (Dublin, Ireland)
    • Year and Date
      2015-09-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Girk2遺伝子コンディショナルノックアウトマウス作製と創薬への応用2015

    • Author(s)
      本多 幾多郎、荒木 喜美、本田 宗吉、副田 二三夫、三隅 将吾、山村 研一、高濱 和夫
    • Organizer
      第26回 霧島神経薬理フォーラム
    • Place of Presentation
      鹿児島市
    • Year and Date
      2015-08-15
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] マウスを用いた疾患遺伝学の展開~基礎研究からベンチャーへ~2015

    • Author(s)
      山村研一
    • Organizer
      北大特別講演会
    • Place of Presentation
      シオノギ創薬イノベーションセンター産学コミュニティホール(北海道札幌市)
    • Year and Date
      2015-07-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] lincRNAの生体内機能解析~遺伝子トラップマウスからのアプローチ~2015

    • Author(s)
      吉信公美子、中原舞、山村研一、荒木喜美、荒木正健
    • Organizer
      第38回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Gene-trap mutagenesis is useful for analysis of long intergenic non-coding RNA genes.2015

    • Author(s)
      Nakahara, M., Yoshinobu, K., Ito, H., Furuhata, R., Yamamura, K., Araki, M. and Araki, K.
    • Organizer
      the 29th Annual Conference of the International Mammalian Genome Society
    • Place of Presentation
      横浜市開港記念会館(神奈川県横浜市)
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] GIRK2 channel KO of neurons expressing dopamine transporters mimics the effect of antitussives on the forced swimming in mice2015

    • Author(s)
      HONDA, K. ARAKI, S. HONDA, F. SOEDA, S. MISUMI, K. YAMAMURA, K. TAKAHAMA
    • Organizer
      2015 Annual meeting of Society for Neuroscience
    • Place of Presentation
      シカゴ(USA)
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] Correlation of LincRNA-p21 and p53 expression in the LincRNA-p21 gene trap mouse2015

    • Author(s)
      Furuhata, R., Nakahara, M., Ito, H., Yamamura, K., Araki, M. and Araki, K.
    • Organizer
      the 29th Annual Conference of the International Mammalian Genome Society
    • Place of Presentation
      横浜市開港記念会館(神奈川県横浜市)
    • Year and Date
      2015-11-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Functional Analysis of TGF-beta pathway in hepatoblasts during mouse hepatic histogenesis2014

    • Author(s)
      Yuji Yokouchi, Naoki Takeda, Hiroshi Sasaki, and Ken-ich Yamamura
    • Organizer
      47th Annual Meeting of the Japanese Society of Developmental Biologists
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23659097
  • [Presentation] ヒト疾患モデルを用いた病因・病態解析と治療法の検証2014

    • Author(s)
      山村研一
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌(札幌コンベンションセンター)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Functional analysis of the TGF-beta pathway in hepatoblasts during mouse hepatic histogenesis. マウス肝組織形成時の肝芽細胞におけるTGF-beta 経路の機能解析2014

    • Author(s)
      Yuji Yokouchi, Daiki Yoshii, Hiroki Takeda, Hiroko Suda, Yukihiro Inomata, and Ken-ichi Yamamura
    • Organizer
      47th Annual Meeting of the Japanese Society of Developmental Biologists. Co-sponsor: Asia-Pacific Developmental Biology Network
    • Place of Presentation
      Nagoya, WINC AICHI
    • Data Source
      KAKENHI-PROJECT-23659097
  • [Presentation] Functional Analysis of TGF-β pathway in hepatoblasts during mouse hepatic histogenesis2014

    • Author(s)
      Yuji Yokouchi, Naoki Takeda, Hiroshi Sasaki, and Ken-ichi Yamamura
    • Organizer
      47th Annual Meeting of the Japanese Society of Developmental Biologists
    • Place of Presentation
      名古屋, WINC AICHI
    • Data Source
      KAKENHI-PROJECT-22390034
  • [Presentation] ヒト化マウスによるヒト疾患解析2014

    • Author(s)
      山村 研一
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ 2014(特別講演)
    • Place of Presentation
      琵琶湖ホテル(大津市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] モデルマウスを用いたシトリン欠損症における糖質毒性の解析2014

    • Author(s)
      佐伯 武頼,藤本 侑希,山村 研一,井上 加奈子,小野 裕美
    • Organizer
      第17回日本病態栄養学会年次学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] 個体レベルのがん研究支援-in vivo解析の重要性-2014

    • Author(s)
      山村研一
    • Organizer
      平成26年度 文部科学省新学術領域研究生命科学系3分野がん・ゲノム・脳支援活動合同シンポジウム
    • Place of Presentation
      一橋大学一橋講堂学術総合センター2F(東京)
    • Year and Date
      2014-05-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] INK4a欠損慢性膵炎モデルマウスにおける膵星細胞の活性化と線維化の促進2013

    • Author(s)
      坂田和也,大村谷昌樹,荒木喜美,佐谷秀行,馬場秀夫,山村研一
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      神奈川(パシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 脊椎形成の分子メカニズムの解析‐マウスからヒトへ‐2013

    • Author(s)
      山村研一
    • Organizer
      第26回日本軟骨代謝学会
    • Place of Presentation
      大阪(千里ライフサイエンスセンター)
    • Year and Date
      2013-03-01
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Plasma glycerol was increased parallel to blood ammonia in citrin deficiency model in response to administration of sugars2013

    • Author(s)
      Saheki T, Fujimoto Y, Yamamura K
    • Organizer
      3rd ACIMD/55th JSIMD
    • Place of Presentation
      Maihama, Japan
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] オートファジー不全がもたらす慢性膵炎発症メカニズムの解析2013

    • Author(s)
      大村谷 昌樹, 荒木 喜美, 山村 研一
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 脊椎形成の分子メカニズムの解析ーマウスからヒトへー2013

    • Author(s)
      山村研一
    • Organizer
      第26回日本軟骨代謝学会(招待講演)
    • Place of Presentation
      千里ライフサイエンスセンター(豊中市)
    • Year and Date
      2013-03-01
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] 脊椎形成の分子メカニズムの解析‐マウスからヒトへ‐2013

    • Author(s)
      山村研一
    • Organizer
      第26回日本軟骨代謝学会
    • Place of Presentation
      大阪(千里ライフサイエンスセンター)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] A possible diagnostic for citrin deficiency; high plasma and urinary glycerol detected in the model, Citrin/ mGPD double-KO mouse2013

    • Author(s)
      Fujimoto Y, Yano K, Yamashita K, Rikimaru S, Inoue K, Yamamura K, Saheki T
    • Organizer
      3rd ACIMD/55th JSIMD
    • Place of Presentation
      Maihama, Japan
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] モデルマウスを用いるシトリン欠損症患者の糖質忌避の機構解析2013

    • Author(s)
      佐伯武頼,藤本侑希,古家澄江,山村研一
    • Organizer
      日本人類遺伝学会第58回大会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] c-Maf遺伝子導入MSM/Msマウスの作出と解析2013

    • Author(s)
      昇地 高雅, 荒木 喜美, 舘山 浩紀, 山村 研一, 高橋 智
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸(神戸ポートアイランド)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Autophagic cell death by SPINK insufficiency induces chronic inflam-mation in the pancreas2013

    • Author(s)
      Ohmuraya, M., Li, Z., Yamamura, K.
    • Organizer
      The 45th Annual Meeting of the European Pancreatic Club
    • Place of Presentation
      Zurich Switzerland (Kongresshaus Zurich)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 慢性膵炎により引き起こされる癌関連遺伝子の異常2013

    • Author(s)
      大村谷昌樹,能登原憲司,荒木喜美,馬場秀夫,山村研一
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      神奈川(パシフィコ横浜)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] オートファジー不全がもたらす慢性膵炎発症メカニズムの解析2013

    • Author(s)
      大村谷 昌樹,荒木喜美,山村研一
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      兵庫(神戸ポートアイランド)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] MSM/Ms由来ES細胞を用いたc-Mafトランスジェニックマウスの作出と解析2013

    • Author(s)
      昇地高雅,舘山浩紀,荒木喜美,高橋 智,山村研一
    • Organizer
      第27回モロシヌス研究会
    • Place of Presentation
      茨城(筑波山 江戸屋)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 古典的なミュータントDanforth's short tail(Sd)に学ぶ2012

    • Author(s)
      山村研一
    • Organizer
      発生工学・疾患モデル研究会(招待講演)
    • Place of Presentation
      東京ガーデンパレス(文京区)
    • Year and Date
      2012-10-23
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] 尾部退行症候群と関連するSickle tail (Skt)遺伝子およびDanforth's short tail (Sd)遺伝子2012

    • Author(s)
      山村研一
    • Organizer
      第103回 BRC セミナー
    • Place of Presentation
      筑波研究所(つくば市)
    • Year and Date
      2012-04-10
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] 可変型相同組換え法によるTtrおよびRbp遺伝子座のダブルヒト化マウスの作製2011

    • Author(s)
      李正花、荒木喜美、作村由美、山村研一
    • Organizer
      34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Presentation] Spink3 is involved in pancreatitis through the regulation of autophagy2011

    • Author(s)
      Yamamura, K., Araki, K., Ohmuraya, M
    • Organizer
      Mouse Genetics 2011
    • Place of Presentation
      Washington DC USA (Omni Shoreham Hotel)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Spink3 is involved in pancreatitis through the regulation of autophagy2011

    • Author(s)
      Yamamura, K.
    • Organizer
      Mouse Genetics 2011
    • Place of Presentation
      Washington DC・USA
    • Year and Date
      2011-06-25
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Production of optimum humanized mouse model for familial amyloidotic polyneuropathy2011

    • Author(s)
      Zhenghua Li, Kimi Araki, Ken-ichi Yamamura
    • Organizer
      Mouse genetics 2011
    • Place of Presentation
      ワシントンD. C.(米国)
    • Year and Date
      2011-06-23
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Presentation] 呼吸器系(肺気腫の表現型解析)2011

    • Author(s)
      山村研一
    • Organizer
      第58回日本実験動物学会総会
    • Place of Presentation
      タワーホール船堀(東京都)(招待講演)
    • Year and Date
      2011-05-27
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 遺伝性膵炎におけるSPINK1/SPink3の役割2011

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第56回大会
    • Place of Presentation
      幕張メッセ(千葉)
    • Year and Date
      2011-11-12
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Production of optimum humanized mouse model for familial amyloidotic polyneuropathy2010

    • Author(s)
      Zhenghua Li, Kimi Araki, Ken-ichi Yamamura
    • Organizer
      The 4^<th> AFLAS Congress Meeting 5^<th> AMMRA Meeting & 11^<th> CSLAS Annual Meeting
    • Place of Presentation
      台北(台湾)
    • Year and Date
      2010-11-10
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Presentation] 膵炎におけるオートファジーの役割(シンポジウム3オートファジーと病態)2010

    • Author(s)
      山村研一
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京(京王プラザホテル)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] ヒト化マウスによる最適FAPモデルの作製2010

    • Author(s)
      李正花、荒木喜美、作村由美、山村研一
    • Organizer
      33回日本分子生物学会年会
    • Place of Presentation
      神戸国際展示場(兵庫県)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21590361
  • [Presentation] MMS/Ms mouse as a tool for humanized mouse project in Japan2010

    • Author(s)
      Yamamura, K.
    • Organizer
      2010 KALAS International Symposium
    • Place of Presentation
      Busan BEXCO Exhibition & Convention Center(韓国)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 典型的な優性遺伝病の発症における環境要因2010

    • Author(s)
      山村研一
    • Organizer
      第57回日本実験動物学会総会
    • Place of Presentation
      京都テルサ(京都府)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 膵炎におけるオートファジーの役割2010

    • Author(s)
      山村研一
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      京王プラザホテル(東京都)(招待講演)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] 理研BRC日本マウスクリニックII : 日本産野生系統MSMの行動解析2010

    • Author(s)
      山田郁子、古瀬民生、串田知子、鈴木智広、桝屋啓志、金田秀貴、小林喜美男、三浦郁生、森脇和郎、山村研一、若菜茂晴
    • Organizer
      第57回日本実験動物学会総会
    • Place of Presentation
      京都(京都テルサ)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Humanized Mice for Functional Genomics and Human Disease Model2010

    • Author(s)
      Yamamura, K.
    • Organizer
      The4^<th> AFLAS Congress Meeting
    • Place of Presentation
      Taipei International Convention Center (台湾)
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] MMS/Ms mouse as a tool for humanized mouse project in Japan2009

    • Author(s)
      Yamamura, K., Araki, K.
    • Organizer
      Fourth meeting on Asian Mouse Mutagenesis and Resource Association
    • Place of Presentation
      Kumamoto
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] Relationship of strain dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression2009

    • Author(s)
      Wang, J., Ohmuraya, M., Suyama, K., Hirota, M., Ozaki, N., Baba, H., Nakagata, N., Araki, K., Yamamura, K
    • Organizer
      Fourth meeting on Asian Mouse Mutagenesis and Resource Association
    • Place of Presentation
      Kumamoto
    • Data Source
      KAKENHI-PROJECT-21220010
  • [Presentation] Pancreatic Acinar Cell Death In Spink3 Deficient Mice2009

    • Author(s)
      Yamamura, K., et al.
    • Organizer
      40^<th> Anniversary Joint Meeting of the American Pancrea tic Association & Japan Pancreas Society
    • Place of Presentation
      Hilton Hawaiian Village (Hawaii, USA)
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ノックアウトマウスプロジェクトはなぜ必要か2009

    • Author(s)
      山村研一
    • Organizer
      第56回日本実験動物学会総会シンポジウム
    • Place of Presentation
      大宮ソニックシティ(埼玉)
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Presentation] Pancreatic Acinar Cell Death In Spink3 Deficient Mice2009

    • Author(s)
      Yamamura, K.
    • Organizer
      40th Anniversary Joint Meeting of the American Pancreatic Association & Japan Pancreas Society
    • Place of Presentation
      Hawaii
    • Year and Date
      2009-11-06
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] MMS/Ms mouse as a tool for humanized mouse project in Japan2009

    • Author(s)
      Yamamura, et al.
    • Organizer
      Fourth meeting on Asian Mouse Mutagenesis and Resource Association
    • Place of Presentation
      Kumamoto University, Greenp is MinamiAso (Kumamoto, Japan)
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ノックアウトマウスプロジェクトはなぜ必要か2009

    • Author(s)
      山村研一
    • Organizer
      第56回日本実験動物学会総会シンポジウム
    • Place of Presentation
      大宮ソニックシティ(埼玉)
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ヒト疾患の遺伝学的解析のためのモデルマウス(シンポジウム)2008

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第53回大会
    • Place of Presentation
      横浜
    • Year and Date
      2008-09-02
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ヒト疾患の遺伝学的解析のためのモデルマウス(シンポジウム)2008

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第53回大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] Role of Spink3 in autophagy regulation and induction of pancreatitis2008

    • Author(s)
      Yamamura, K.
    • Organizer
      11^<th> International Symposium on Molecular Medicine
    • Place of Presentation
      Crete island, Greece
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] Exchangeable gene trap as a tool in the mouse knockout project(symposium), The 12th International Symposium for Mouse Genomics The BK21 International Symposium of Veterinary Science2007

    • Author(s)
      Ken-ichi Yamamura
    • Organizer
      Seoul National University
    • Place of Presentation
      Korea
    • Year and Date
      2007-05-15
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ヒト疾患研究における動物モデルの有用性と世界の現状2007

    • Author(s)
      山村 研一
    • Organizer
      第52回大会日本人類遺伝学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] 世界のノックアウトプロジェクト2007

    • Author(s)
      山村研一
    • Organizer
      第24回日本疾患モデル学会総会シンポジウム
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] ヒト疾患研究における動物モデルの有用性と世界の現状(教育講演)2007

    • Author(s)
      山村研一
    • Organizer
      第52 回大会日本人類遺伝学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] ES細胞においてlox71部位に対して良い組換え効率を示す新たなRE変異loxの探索2007

    • Author(s)
      荒木喜美, 岡田由香, 荒木正健, 山村研一
    • Organizer
      第40回日本発生生物学会・第50回日本細胞生物学会合同大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Presentation] 世界のノックアウトプロジェクト(シンポジウム)2007

    • Author(s)
      山村研一
    • Organizer
      第24 回日本疾患モデル学会総会
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] 世界のノックアウトプロジェクト2007

    • Author(s)
      山村研一
    • Organizer
      第24回日本疾患モデル学会総会シンポジウム
    • Place of Presentation
      つくば
    • Data Source
      KAKENHI-PROJECT-17012017
  • [Presentation] ヒト疾患研究における動物モデルの有用性と世界の現状(教育講演2)2007

    • Author(s)
      山村研一
    • Organizer
      第52回大会日本人類遺伝学会ゲ ノム解析から臨床応用へのロードマップ
    • Place of Presentation
      東京
    • Year and Date
      2007-09-14
    • Data Source
      KAKENHI-PROJECT-17012018
  • [Presentation] Gene-environment Interactions in Mammalian Development and Disease2006

    • Author(s)
      Yamamura, K.
    • Organizer
      The 22^<nd> International Kumamoto Medical Bioscience Symposium
    • Place of Presentation
      Kumamoto
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] ヒト疾患の解析における新しいマウスモデル2006

    • Author(s)
      山村研一
    • Organizer
      第3 回日本癌学会カンファレンス動物モデルによる新時代のがん研究発症機構から治療まで
    • Place of Presentation
      長野
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] ポストゲノムにおける疾患モデルの意義2006

    • Author(s)
      山村研一
    • Organizer
      第3 回日本病理学会カンファレンス日本病理学会カンファレンス2006 東京「疾患モデルの命題ー本質を見極めるー」
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] MSM/Ms 由来のES 細胞の樹立とノックアウトプロジェクト2006

    • Author(s)
      山村研一
    • Organizer
      平成17年度国立遺伝学研究所研究会第20 回モノシヌス研究会
    • Place of Presentation
      熱海
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] 優性遺伝病マウスモデルおよび大規模疾患モデル開発2006

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第51回大会The 51th Annual Meeting of the Japan Society of Human Genetics
    • Place of Presentation
      米子
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] ポストゲノムにおける遺伝子改変動物の役割2006

    • Author(s)
      山村研一
    • Organizer
      教育セミナーフォーラム2006テーマ「実験動物及び畜産分野におけるトランスジェニック技術」(遺伝子組換え技術入門)
    • Place of Presentation
      東京
    • Year and Date
      2006-03-25
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] ヒト疾患モデルの大規模作製2005

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第50 回大会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-17200028
  • [Presentation] 脊椎形成の分子メカニズムの解析ーマウスからヒトへー

    • Author(s)
      山村 研一
    • Organizer
      第26回日本軟骨代謝学会
    • Place of Presentation
      豊中市、千里ライフサイエンスセンター
    • Invited
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] ヒトiPSを活用した肝臓ヒト化マウスの作製と応用

    • Author(s)
      山村研一
    • Organizer
      日本人類遺伝学会第59回大会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2014-11-19 – 2014-11-22
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] 可変型遺伝子トラップクローンデータベース[EGTC]の開発と解析

    • Author(s)
      荒木正健, 中原舞, 柳井千佳, 山添史雅, 宮家幹子, 森田彩香, 荒木美幸, 岡本瀬幸, 中潟直己, 吉信公美子, 山村研一, 荒木喜美
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] CHOP欠損による慢性炎症からの膵線維化進展

    • Author(s)
      高城克暢, 大村谷昌樹, 橋本大輔, 東孝暁, 坂本慶太, 坂田和也, 新田英利, 林洋光, 近本亮, 別府透, 荒木喜美, 山村研一, 馬場秀夫
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] MSM/Ms由来ES細胞を用いたc-MafトランスジェニックMSM/Msマウスラインの作出と解析

    • Author(s)
      昇地高雅, 舘山浩紀, 山村研一, 高橋智, 荒木喜美
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ヒト化マウスによるヒト疾患解析

    • Author(s)
      山村研一
    • Organizer
      平成25年度「個体レベルでのがん支援活動」ワークショップ 2014(特別講演)
    • Place of Presentation
      琵琶湖ホテル、滋賀県大津市
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] Functional analysis of the TGF-β pathway in hepatoblasts during mouse hepatic histogenesis.

    • Author(s)
      Yokouchi, Y., Yoshii, D., Takeda, H., Suda, H., Inomata, Y., Yamamura, K.
    • Organizer
      第47回日本発生生物学会
    • Place of Presentation
      ウインクあいち(愛知県・名古屋市)
    • Year and Date
      2014-05-27 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] オートファジー不全と慢性膵炎発症メカニズムの解明

    • Author(s)
      大村谷昌樹, 坂田和也, 高城克暢, 松元美由紀, 荒木喜美, 山村研一
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] ヒト疾患モデルを用いた病因・病態解析と治療法の検証

    • Author(s)
      山村研一
    • Organizer
      第61回日本実験動物学会総会
    • Place of Presentation
      札幌コンベンションセンター(北海道・札幌市)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] SPINK1ノックインマウスではオートファジー機能不全により慢性膵炎が惹起される

    • Author(s)
      坂田和也, 大村谷昌樹, 荒木喜美, 高城克暢, 橋本大輔, 近本亮, 山村研一, 馬場秀夫
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] シトリン欠損症の病態解析と治療法の開発:現在の課題

    • Author(s)
      佐伯武頼、藤本侑希、古家澄江、山村研一
    • Organizer
      第56回日本先天代謝異常学会・第12回アジア先天代謝異常症シンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2014-11-13 – 2014-11-15
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] 尾部退行症候群と関連するSickle tail (Skt)遺伝子および Danforth’s short tail (Sd)遺伝子

    • Author(s)
      山村 研一
    • Organizer
      第103回BRCセミナー
    • Place of Presentation
      つくば市、筑波研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] 「再生医療における非臨床試験とは:ヒトiPS細胞を用いたヒト化マウス」

    • Author(s)
      山村研一
    • Organizer
      第22回熊本大学医学部附属病院 臨床カンファレンス
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] CRISPR/Cas9による2本鎖切断・1本鎖切断を利用した場合のマウスES細胞における相同組換え効率の比較

    • Author(s)
      荒木喜美, 牟田真由美, 仙波圭, 竹田直樹, 仁木大輔, 松本健, 武田伊世, 山村研一, 大村谷昌樹, 荒木正健
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Presentation] GIRK2 channel KO of neurons expressing dopamine transporters mimics the effect of antitussives on the forced swimming in mice

    • Author(s)
      Honda I., Araki K., Honda S., Soeda1., Misumi S., Yamamura K., Takahama K.
    • Organizer
      Society for Neuroscience 2015
    • Place of Presentation
      Chicago
    • Year and Date
      2015-10-17 – 2015-10-21
    • Data Source
      KAKENHI-PROJECT-26460114
  • [Presentation] Functional Analysis of TGF-beta pathway in hepatoblasts during mouse hepatic histogenesis

    • Author(s)
      Yuji Yokouchi, Naoki Takeda, Hiroshi Sasaki, and Ken-ich Yamamura
    • Organizer
      47th Annual Meeting of the Japanese Society of Developmental Biologists
    • Place of Presentation
      名古屋, WINC AICHI
    • Year and Date
      2014-05-27 – 2014-05-30
    • Data Source
      KAKENHI-PROJECT-22390034
  • [Presentation] Metabolic basis of carbohydrate toxicity in citrin, liver-type mitochondrial aspartate glutamate carrier, deficiency

    • Author(s)
      Saheki T, Fujimoto Y, Furuie S, Yamamura K,
    • Organizer
      Asia Europe Workshop on Inborn Error of Metabolism (AEWIEM) 2015
    • Place of Presentation
      エジプト(カイロ)
    • Year and Date
      2015-01-18 – 2015-01-19
    • Data Source
      KAKENHI-PROJECT-24591516
  • [Presentation] 古典的なミュータントDanforth's short tail(Sd)に学ぶ

    • Author(s)
      山村 研一
    • Organizer
      発生工学・疾患モデル研究会
    • Place of Presentation
      文京区、東京ガーデンパレス
    • Invited
    • Data Source
      KAKENHI-PROJECT-22791388
  • [Presentation] Pathophysiology of citrin deficiency and current progress on its treatment

    • Author(s)
      Takeyori Saheki, Yuki Fujimoto, Sumie Furuie, Ken-ichi Yamamura, Masahide Yazaki, Shu-ichi Ikeda
    • Organizer
      Asia Conference on Inhertited Metabolic Disease (ACIMD) 2015
    • Place of Presentation
      台湾(台北)
    • Year and Date
      2015-03-20 – 2015-03-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24591516
  • []

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  • 283.  井田 智
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    # of Collaborated Products: 1 results
  • 284.  新井 郷子
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