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Miyazono Kouhei  宮園 浩平

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MIYAZONO Kohei  宮園 浩平

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Researcher Number 90209908
Other IDs
External Links
Affiliation (Current) 2025: 東京大学, 大学院医学系研究科(医学部), 客員教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 東京大学, 大学院医学系研究科(医学部), 卓越教授
2015 – 2020: 東京大学, 大学院医学系研究科(医学部), 教授
2015: 東京大学, 医学系研究科, 教授
2010 – 2015: The University of Tokyo, 医学(系)研究科(研究院), 教授
2000 – 2012: Tokyo University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授 … More
2010: 東京大学, 医学部, 教授/学部長
2004 – 2006: The University of Tokyo, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授
2004: 東京大学, 大学院・医学研究科, 教授
2000: Graduate Sch.Med., University of Tokyo, Professor, 医学系研究科, 教授
1999: 財団法人 癌研究会, 部長、研究職
1999: 財団法人 癌研究会, 癌研究所・生化学部, 部長
1999: 財団法人 癌研究会, 癌研究所生化学部, 部長(研究職)
1998 – 1999: 癌研究所, 生化学部, 部長
1997 – 1999: 癌研究会, 附属研究所・生化学部, 部長
1998: (財)癌研究会, 癌研究所, 部長 研究職
1998: 癌研究会, 癌研究所生化学部, 部長
1997 – 1998: 財団法人癌研究会, 癌研究所・生化学部, 部長
1997: Japanese Foundation for Cancer Research the Cancer Institute, Tokyo., Chief., 癌研究所, 部長
1997: (財)癌研究会癌研究所, 生化学部, 部長(研究職)
1996 – 1997: The Cancer Institute, Department of Biochemistry, Chief, 癌研究所生化学部, 部長
1995 – 1997: 財団法人癌研究會, 癌研究所・生化学部, 部長
1996: Japanese Foundation for Cancer Research The Cancer Institute, Dept.Biochemistry,, 癌研究所生化学部, 部長
1996: (財)癌研究会癌研究所, 部長
1995 – 1996: 財団法人癌研究會, 癌研究所生化学部, 部長
1995: (財)癌研究会, 癌研究所, 部長
1995: 癌研究所, 部長
1995: 財団法人癌研究曾, 癌研究所・生化学部, 部長
1991 – 1992: 東京大学, 医学部・(病), 助手
1991: 東京大学, 医学部(病), 助手
1990: Third Dept. of Int. Med. Medicine Instructor Univ. of Tokyo, 医学部(病)第三内科, 助手
1990: 東京大学, 医学部・第三内科, 助手
1989: 東京大学, 医学部(病), 助手
1989: 東京大学, 医学部(病)・第三内科, 助手
1989: 東京大学, 医学部第三内科, 助手
1989: 東京大学医学部(病), 第三内科, 助手 Less
Review Section/Research Field
Principal Investigator
Cell biology / Pathological medical chemistry / Biological Sciences / Experimental pathology / Biological Sciences / Broad Section I / Medium-sized Section 50:Oncology and related fields / Complex systems / Tumor biology / Hematology … More / General medical chemistry / Tumor biology / Pathological medical chemistry / General medical chemistry … More
Except Principal Investigator
Biological Sciences / Complex systems / Immunology / Experimental pathology / Hematology / General surgery / Functional basic dentistry / 内科学一般 / Experimental pathology / General medical chemistry Less
Keywords
Principal Investigator
シグナル伝達 / TGF-β / Smad / 血管新生 / レセプター / signal transduction / 増殖抑制 / BMP / TGF-beta / がん微小環境 … More / 発生・分化 / 転移 / セリン-スレオニンキナーゼ / 骨形成因子 / アクチビン / receptor / 受容体 / リンパ管新生 / がん幹細胞 / 癌抑制遺伝子 / アポトーシス / 細胞分化 / cDNAクローニング / angiogenesis / threonine kinase / serine / セリン・スレオニンキナーゼ / ゲノム科学 / 微小環境 / 血管内皮細胞 / 癌 / 病理学 / 実験動物モデル / 分子イメージング / 浸潤・転移 / DNAP / cell differentiation / 骨芽細胞 / growth inhibition / tumor suppressor gene / セリン-スレオニン・キナーゼ / GM-CSF / 細胞内シグナル伝達 / 細胞医化学 / がん浸潤 / 生体イメージング / 生体材料 / 転写因子 / 免疫抑制剤 / osteoblast / ES cell / 平滑筋細胞 / ES細胞 / transcription factor / ubiquitination / anti-oncogene / oncogene / がんの浸潤・転移 / シグナルクロストーク / Wntシグナル / Smurf1 / c-myc / ユビチキン化 / ユビキチン化 / 癌遺伝子 / mass-spectrometry / protein-protein interaction / アミノ酸配列 / 質量分析 / 構造決定 / マススペクトロメトリー / 蛋白質間相互作用 / transcription / endotelial cell / invasion / DNA microarray / 表皮角化細胞 / 転写調節 / 浸潤 / DNAマイクロアレイ / gene targeting / 遺伝子ターゲッテイング / keratinocyte / bone morphogenetic protein / activin / 皮膚角化細胞 / apoptosis / soluble receptor / IL-3 / colony-stimulating factor / インタ-ロイキン3 / 造血因子 / 分泌型受容体 / コロニ-刺激因子 / 分泌性受容体 / ILー3 / GMーCSF / 発生医学 / ゲノム医化学 / EMT / ゲノム医学 / 動脈硬化 / 血管平滑筋細胞 / 血管 / 再生医学 / シグナル亢進 / 免疫 / Smad7 / DDS / 乳がん / 膵臓がん / がん朝細胞 / 脳腫瘍 / 胃がん / シグナル伝逹 / 分子標的治療 / 細胞増殖 / 情報伝達 / 免疫病 / 免疫異常 / 抗原受容体 / STAT / リンパ球 / サイトカイン / リン酸化 / ファルネシレーション / FKBP-12 / 形態形成 / 白血病 / 増殖因子 / 潜在型TGFーbeta / TGFーbeta … More
Except Principal Investigator
TGF-β / シグナル伝達 / Smad / アポトーシス / BMP / 血管新生 / 癌抑制遺伝子 / がん抑制遺伝子 / がん細胞 / がん遺伝子 / がん転移 / 細胞死 / 遺伝子 / 再生医療 / 臨床 / 細胞・組織 / 癌 / Lyn / Src / SSl-1 / STAT / FasL / TGF-beta / GDF / サイトカイン / signal transduction / apoptosis / 増殖因子 / 若手支援 / 国際交流 / 分子標的治療 / 分子標的 / 内皮細胞 / ショウジョウバエ / 2国間共同研究 / ヒトゲノム / DNA修復 / 情報伝達 / レパートリー形成 / 免疫病 / ヒトがん / 細胞分化 / 細胞増殖 / 細胞間相互作用 / 分化 / がん / 肝臓 / 血管内皮細胞 / 血小板由来血管内皮細胞増殖因子 / 病理学 / 数理科学 / がん分子標的薬剤 / ATL発症リスク / ATL発がん機序 / がん化学予防 / 分子疫学コーホート研究 / ATL発症予防 / 個別化がん予防 / ゲノム・エピゲノム解析支援 / アカデミア創薬 / 次世代分子解析技術 / ゲノムコーホート研究 / 病理形態学 / 遺伝子改変マウス / 国際研究者交流 / Aplastic anemia / Bone marrow transplantation / Leukemia / Hematopoietic growth factors / Neutropenia / Colony-stimulating factor / コロニー刺激因子 / 造血幹細胞 / エリスロポエチン / インタ-ロイキンー1 / インタ-ロイキンー3 / GMーCSF / MーCSF / GーCSF / 再生不良性貧血 / 骨髄移植 / 白血病 / コロニ-刺激因子 / 好中球減少症 / 造血因子 / anticancer agent / immune response / Cytokine / tumore supressor gene / cell adhesion / advanced research / がん予防 / がん診断 / 発がん / がん研究 / 抗がん剤 / 免疫応答 / 細胞接着 / 先端的研究 / Tumor suppressor gene / 遺伝子診断 / CD40-CD40L / TCR-peptides / CD40 / TCR / threonine kinase / Receptor serine / TGF-beta superfamily / スレオニンキナーゼ型受容体 / セリン / TGF-βスーパーファミリー / IL-5 / Signal transduction / Immunological disorders / Inflammation / Tyrosine kinase / Immunodiversity / Antigen receptor / Repertoire selection / 自己免疫疾患 / 免疫不全 / 自己認識 / 免疫病の分子機構 / アレルギー / 自己免疫病 / 抗原レセプター / MHCと抗原ペプチド / 免疫寛容 / 免疫制御 / 免疫職別の多様性 / 免疫職別の多型性 / 新しい診断法 / 免疫病とその修復 / リンパ球の機能分化 / 免疫識別の多様性 / 免疫識別の多型性 / 免疫異常 / tumor suppressor gene / oncogene / human cancer / cancer metastasis / cell-cell interaction / cell differentiation / cell growth / Transcriptional regulation / Placenta / Epithelial cell / Angiogenesis / Growth factor / Endothelial cell / Platelet / 転写調節 / 胎盤 / 上皮細胞 / 成長因子 / 血小板 / 分子生物学 / 脳腫瘍 / DACH1 / 癌幹細胞 / 広報活動 / 青少年育成 / 広報支援 / 新しい物療法 / トランスレーショナルリサーチ / 分子創薬 / トランスレーショナル・リサーチ / 新しい物理療法 / ドラッグデリバリーシステム / ゲノム / SNP / 化学予防 / プロテオミクス / 民族疫学 / オーダーメイド医療 / 骨格系 / 転写因子 / 骨形成因子 / 動脈硬化 / 血管 / 多量体 / リン酸化 / レセプター / セリン・スレオニンキナーゼ / 膵臓癌 / DPC4 / 2国間協同研究 / 精製 / 角化細胞 / 増殖抑制因子 / マクロファージ / 単球 / 血液細胞 / 機能分化 / 免疫識別 / アボトーシス / 細胞生物学 / 転移 / 増殖 / thymidine phosphorylase / 燐酸化 / (血小板由来血管内皮細胞増殖因子) / PD-ECGF / 肝癌 / テロシンキナ-ゼ / 癌関連遺伝子 / fps癌遺伝子 / tec遺伝子 / ltk遺伝子 Less
  • Research Projects

    (57 results)
  • Research Products

    (365 results)
  • Co-Researchers

    (269 People)
  •  Study on the Mechanisms of the Induction of Mesenchymal Cancer Cells and Their Plasticity and DiversityPrincipal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section I
    • Research Institution
      The University of Tokyo
  •  Integrated analysis and regulation of cellular diversity

    • Principal Investigator
      藤田 直也
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Comprehensive Studies on the Mechanisms of Cancer Metastasis from Molecular Signaling to Whole-Body LevelPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      The University of Tokyo
  •  Integrated analysis and regulation of cellular diversity

    • Principal Investigator
      FUJITA Naoya
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Molecular mechanisms of cell differentiation and diversity by TGF-beta family membersPrincipal Investigator

    • Principal Investigator
      Miyazono Kohei
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      The University of Tokyo
  •  Transcriptional regulation by TGF-beta signaling and its relation to progression of cancerPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo
  •  Roles of BMP signaling in maintenance of cell stemnessPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokyo
  •  Integrative Research on Cancer Microenvironment NetworkPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Effects of TGF-beta family on cancer microenvironment and strategies for cancer therapyPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  がん微小環境の制御機構Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      2010
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Tumor biology
    • Research Institution
      The University of Tokyo
  •  Integrative Research on Cancer Microenvironment NetworkArea Organizer

    • Area Organizer
      MIYAZONO Kohei
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Scientific Support Programs for Cancer Research Grant-in-Aid for Scientific Research on Innovative Areas

    • Principal Investigator
      IMAI Kohzoh, 中村 祐輔
    • Project Period (FY)
      2010 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      The University of Tokyo
  •  Transcriptional network regulate d by a candidate tumor suppressor gene DA CH1

    • Principal Investigator
      WATANABE Akira
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Kyoto University
  •  間葉-上皮細胞分化転換の分子機構Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  Mechanisms for regulation of lymphangiogenesisPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokyo
  •  血管内皮-壁細胞分化転換の分子機構Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  The core unit supporting research, communication, network and young scientists in the cancer research field

    • Principal Investigator
      NAKAMURA Takuro
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Establishment of New Strategies for Treatment of Cancer Using TGF-beta SignalingPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Diagnosis, Epidemiology, and Chemoprevention of Cancer

    • Principal Investigator
      NAKAMURA Yusuke
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  New therapeutic strategies for treatment of cancer based on basic research

    • Principal Investigator
      UEDA Ryuzo
    • Project Period (FY)
      2004 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Nagoya City University
  •  Study on cell biological activities of serine-threonine kinase receptorsPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  骨格系の制御プログラムにおける骨形成因子の機能と役割

    • Principal Investigator
      今村 健志
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Mechanisms of TGF-β signaling and its abnormalities in human cancerPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  がんの生物学的特性の研究の総括

    • Principal Investigator
      SASAZUKI Takehiko, KUROKI Toshio
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
      Showa University
      The University of Tokyo
  •  ヨーロッパなどががん研究先進国との研究交流

    • Principal Investigator
      黒木 登志夫
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Field
      Experimental pathology
    • Research Institution
      Showa University
  •  BMPsとアクチビンの細胞内シグナル伝達因子Smadの機能解析

    • Principal Investigator
      今村 健志
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Advanced research on cancer

    • Principal Investigator
      TANIGUCHI Tadatsugu
    • Project Period (FY)
      1999 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokyo
  •  Signal transduction by Smad proteins and their biological activitiesPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
      Japanese Foundation For Cancer Research
  •  Development of methods using protein-protein interaction to identify signaling proteinsPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      The University of Tokyo
      Japanese Foundation For Cancer Research
  •  Smadがん抑制遺伝子産物による細胞増殖制御機構の解明

    • Principal Investigator
      川畑 正博
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  セリン・スレオニンキナーゼ型レセプターの情報伝達経路の解明

    • Principal Investigator
      川畑 正博
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  TGF-Bによる血管壁細胞の増殖調節機構の分子レベルでの解明

    • Principal Investigator
      川畑 正博
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Immunology
    • Research Institution
      Juntendo University School of Medicine
  •  Genomic structure and functional analysis of the MAD related gene.

    • Principal Investigator
      TAKENOSHITA Seiichi
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      General surgery
    • Research Institution
      FUKUSHIMA MEDICAL UNIVERSITY
      Gunma University
  •  Signainrg Mechanism and Biological Action of the Members of the Transforming Growh Factor beta SuperfamilyPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  TGF-βスーパーファミリーによる造血調節に関する基礎研究

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  癌細胞の形質特異性とTGF-βファミリー因子群のシグナル伝達異常

    • Principal Investigator
      一條 秀憲
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  情報伝達とリンパ球の機能分化Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  角化細胞増殖抑制因子の同定

    • Principal Investigator
      加藤 光保
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Molecular Mechanisms and Intervention of Immunological Diseases.

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1996 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  STUDY FOR INTRACELLULAR SIGNAL TRANSDUCTION MECHANISM OF TGF-beta SUPERFAMILY.

    • Principal Investigator
      ICHIJO Hidenori
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Bioactivity and Clinical Application of New Members in the TGF-beta SuperfamilyPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Cell biology
    • Research Institution
      Japanese Foundation for Cancer Research
  •  形態形成におけるアクチビンおよび骨形成因子レセプターの役割Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  血球細胞でのTGF-βとアクチビンレセプターの発現と造血調節機構の研究Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  癌細胞の自律性増殖におけるTGF-βのシグナル伝達機構の役割Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Japanese Foundation For Cancer Research
  •  免疫病の分子機構とその修復

    • Principal Investigator
      TAKATSU Kiyoshi
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Immunology
    • Research Institution
      The University of Tokyo
  •  TGF-βレセプターによるシグナル伝達機構の研究Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Japanese Foundation For Cancer Research
  •  Mechanism of Action and Clinical Application of the Type beta Transforming Growth FactorPrincipal Investigator

    • Principal Investigator
      MIYAZONO Kohei
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Showa University
      The University of Tokyo
  •  血小板由来血管内細胞増殖因子の生理的意義の解析

    • Principal Investigator
      豊島 秀男
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  血小板由来血管内皮細胞増殖因子の生理的意義の解析

    • Principal Investigator
      TOYOSHIMA Hideo
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  悪性腫瘍の増殖,浸潤,転移における血小板由来血管内皮細胞増殖因子の役割の研究

    • Principal Investigator
      豊島 秀男
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      The University of Tokyo
  •  beta型トランスフォーミング増殖因子(TGFーbeta)の作用機構の基礎的研究Principal Investigator

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokyo
  •  造血腫瘍の新しい癌関連遺伝子単離技術の開発

    • Principal Investigator
      石川 冬木
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      The University of Tokyo
  •  Characterization of receptors for human colony-stimulating factor (GM-CSF and IL-3)Principal Investigator

    • Principal Investigator
      MIYAGAWA Kiyoshi, 宮園 浩平
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokyo University
  •  In Vitro and In Vivo Function of Platelet-Derived Endothelial Cell Growth Factor

    • Principal Investigator
      MIYAGAWA Kiyoshi, TAKAKU Fumimaro
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      内科学一般
    • Research Institution
      University of Tokyo
  •  Basic Research and Clinical Application of Hematopoietic Growth Factors

    • Principal Investigator
      YAMAJI Tohru, 高久 史磨 (高久 史麿)
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Hematology
    • Research Institution
      Faculty of Medicine, University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent Other

  • [Book] The Biology of the TGF-β Family (Cold Spring Harbor Perspectives in Biology)2017

    • Author(s)
      Derynck R, Miyazono K (editors)
    • Total Pages
      1164
    • Publisher
      Cold Spring Harbor Laboratory Press
    • ISBN
      9781621820369
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Book] The TGF-βFamily.2008

    • Author(s)
      Derynck, R., Miyazono, K., eds.
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Book] The TGF-β Family2008

    • Author(s)
      Derynck, R. and Miyazono, K.
    • Total Pages
      1093
    • Publisher
      Cold Spring Harbor Laboratory Press
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Receptor-activated transcription factors and beyond: multiple modes of Smad2/3-dependent transmission of TGF-β signaling2024

    • Author(s)
      Miyazawa Keiji、Itoh Yuka、Fu Hao、Miyazono Kohei
    • Journal Title

      Journal of Biological Chemistry

      Volume: 300 Issue: 5 Pages: 107256-107256

    • DOI

      10.1016/j.jbc.2024.107256

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19KK0400, KAKENHI-PROJECT-20H00513, KAKENHI-PROJECT-23K21385
  • [Journal Article] Tissue clearing method in visualization of cancer progression and metastasis2024

    • Author(s)
      Takahashi-Yamashiro Kei, Miyazono Kohei
    • Journal Title

      Upsala Journal of Medical Sciences

      Volume: 129

    • DOI

      10.48101/ujms.v129.10634

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Journal Article] Inhibition of transforming growth factor‐β signals suppresses tumor formation by regulation of tumor microenvironment networks2023

    • Author(s)
      Tokizaki Shiori、Podyma‐Inoue Katarzyna A.、Matsumoto Takehisa、Takahashi Kazuki、Kobayashi Miho、Ibi Haruka、Uchida Shizuka、Iwabuchi Sadahiro、Harada Hiroyuki、Hashimoto Shinichi、Miyazono Kohei、Shirouzu Mikako、Watabe Tetsuro
    • Journal Title

      Cancer Science

      Volume: 115 Issue: 1 Pages: 211-226

    • DOI

      10.1111/cas.16006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07727, KAKENHI-PROJECT-20H00513, KAKENHI-PROJECT-23H05486
  • [Journal Article] An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis2022

    • Author(s)
      Takahashi K, Abe K, Kubota SI, Fukatsu N, Morishita Y, Yoshimatsu Y, Satoshi Hirakawa, Yoshiaki Kubota, Tetsuro Watabe, Shogo Ehata, Hiroki R. Ueda, Teppei Shimamura, Kohei Miyazono
    • Journal Title

      Nature Communiactions

      Volume: 13 Issue: 1 Pages: 5239-5239

    • DOI

      10.1038/s41467-022-32848-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07094, KAKENHI-PROJECT-22K15435, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PLANNED-17H06326, KAKENHI-ORGANIZER-19H05794, KAKENHI-PROJECT-20H00513
  • [Journal Article] Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 Years2022

    • Author(s)
      Ehata Shogo、Miyazono Kohei
    • Journal Title

      Frontiers in Cell and Developmental Biology

      Volume: 10 Pages: 101306-101306

    • DOI

      10.3389/fcell.2022.883523

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-20H00513
  • [Journal Article] An in vivo orthotopic serial passaging model for a metastatic renal cancer study2022

    • Author(s)
      Jun Nishida, Kosuke Miyakuni, Kohei Miyazono, Shogo Ehata
    • Journal Title

      STAR Protocols

      Volume: 3 Issue: 2 Pages: 101306-101306

    • DOI

      10.1016/j.xpro.2022.101306

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21J12321, KAKENHI-PLANNED-17H06326
  • [Journal Article] TGF-β generates a population of cancer cells residing in G1 phase with high motility and metastatic potential via KRTAP2-32022

    • Author(s)
      Takahashi Kazuki、Podyma-Inoue Katarzyna A.、Saito Maki、Sakakitani Shintaro、Sugauchi Akinari、Iida Keita、Iwabuchi Sadahiro、Koinuma Daizo、Kurioka Kyoko、Konishi Toru、Tanaka Susumu、Kaida Atsushi、Miura Masahiko、Hashimoto Shinichi、Okada Mariko、Uchihashi Toshihiro、Miyazono Kohei、Watabe Tetsuro
    • Journal Title

      Cell Reports

      Volume: 40 Issue: 13 Pages: 111411-111411

    • DOI

      10.1016/j.celrep.2022.111411

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K10137, KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-20K10111, KAKENHI-PROJECT-20H00513
  • [Journal Article] Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer2022

    • Author(s)
      Kosuke Miyakuni, Jun Nishida, Daizo Koinuma, Genta Nagae, Hiroyuki Aburatani, Kohei Miyazono, Shogo Ehata
    • Journal Title

      Molecular Oncology

      Volume: 16 Issue: 3 Pages: 732-749

    • DOI

      10.1002/1878-0261.13040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21J12321, KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-23K21431
  • [Journal Article] Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing.2021

    • Author(s)
      Kubota SI, Takahashi K, Mano T, Matsumoto K, Katsumata T, Shi S, Tainaka K, Ueda HR, Ehata S, Miyazono K.
    • Journal Title

      Commun. Biol.

      Volume: 4 Issue: 1 Pages: 294-294

    • DOI

      10.1038/s42003-021-01786-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K21246, KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19J13071, KAKENHI-PROJECT-20K16212, KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-19K16487, KAKENHI-PLANNED-20H05903
  • [Journal Article] Malignant subclone drives metastasis of genetically and phenotypically heterogenous cell clusters through fibrotic niche generation2021

    • Author(s)
      Kok Sau Yee、Oshima Hiroko、Takahashi Kei、Nakayama Mizuho、Murakami Kazuhiro、Ueda Hiroki R.、Miyazono Kohei、Oshima Masanobu
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 863-863

    • DOI

      10.1038/s41467-021-21160-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19K22558, KAKENHI-PROJECT-19K16604, KAKENHI-PROJECT-19H03498
  • [Journal Article] Visualization of the cancer cell cycle by tissue-clearing technology using the Fucci reporter system.2021

    • Author(s)
      Kei Takahashi, Ryo Tanabe, Shogo Ehata, Shimpei I Kubota, Yasuyuki Morishita, Hiroki R Ueda, Kohei Miyazono
    • Journal Title

      Cancer science

      Volume: 112 Issue: 9 Pages: 3796-3809

    • DOI

      10.1111/cas.15034

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16212, KAKENHI-PROJECT-20H00513, KAKENHI-PLANNED-17H06326
  • [Journal Article] PRRX1 induced by BMP signaling decreases tumorigenesis by epigenetically regulating glioma‐initiating cell properties via DNA methyltransferase 3A2021

    • Author(s)
      Tanabe Ryo、Miyazono Kohei、Todo Tomoki、Saito Nobuhito、Iwata Caname、Komuro Akiyoshi、Sakai Satoshi、Raja Erna、Koinuma Daizo、Morikawa Masato、Westermark Bengt、Heldin Carl‐Henrik
    • Journal Title

      Molecular Oncology

      Volume: 16 Issue: 1 Pages: 269-288

    • DOI

      10.1002/1878-0261.13051

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06829, KAKENHI-PLANNED-17H06326
  • [Journal Article] PolyI:C attenuates transforming growth factor‐β signaling to induce cytostasis of surrounding cells by secreted factors in triple‐negative breast cancer2021

    • Author(s)
      Tamura Yusuke、Tsutsumi Shuichi、Miyazono Kohei、Koinuma Daizo
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 3 Pages: 940-949

    • DOI

      10.1111/cas.15241

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Journal Article] Heterogenous expression of endoglin marks advanced renal cancer with distinct tumor microenvironment fitness.2021

    • Author(s)
      Yusaku Momoi, Jun Nishida, Kosuke Miyakuni, Masafumi Kuroda, Shimpei I Kubota, Kohei Miyazono, Shogo Ehata
    • Journal Title

      Cancer science

      Volume: 112 Issue: 8 Pages: 3136-3149

    • DOI

      10.1111/cas.15007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K16212, KAKENHI-PROJECT-21J12321, KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326
  • [Journal Article] Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis2020

    • Author(s)
      Nishida Jun、Momoi Yusaku、Miyakuni Kosuke、Tamura Yusuke、Takahashi Kei、Koinuma Daizo、Miyazono Kohei、Ehata Shogo
    • Journal Title

      Nature Cell Biology

      Volume: 110 Issue: 4 Pages: 2063-2074

    • DOI

      10.1038/s41556-020-0491-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K07684, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06326
  • [Journal Article] Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing2020

    • Author(s)
      Takahashi Kei, Kubota Shimpei I., Ehata Shogo, Ueda Hiroki R., Miyazono Kohei
    • Journal Title

      STAR Protocols

      Volume: 1 Issue: 3 Pages: 100191-100191

    • DOI

      10.1016/j.xpro.2020.100191

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-19K16604, KAKENHI-PROJECT-20H00513
  • [Journal Article] Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer2020

    • Author(s)
      Takahashi Kazuki, Akatsu Yuichi, Podyma-Inoue Katarzyna A., Matsumoto Takehisa, Takahashi Hitomi, Yoshimatsu Yasuhiro, Koinuma Daizo, Shirouzu Mikako, Miyazono Kohei, Watabe Tetsuro
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 36 Pages: 12559-12572

    • DOI

      10.1074/jbc.ra120.012492

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-20J11926, KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-17K11828, KAKENHI-PROJECT-20H03851
  • [Journal Article] Neurotensin receptor 1 signaling promotes pancreatic cancer progression2020

    • Author(s)
      Takahashi Kei、Ehata Shogo、Miyauchi Kensuke、Morishita Yasuyuki、Miyazawa Keiji、Miyazono Kohei
    • Journal Title

      Molecular Oncology

      Volume: 15 Issue: 1 Pages: 151-166

    • DOI

      10.1002/1878-0261.12815

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Journal Article] The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension2019

    • Author(s)
      Morikawa M、Mitani Y、Holmborn K、Kato T、Koinuma D、Maruyama J、Vasilaki E、Sawada H、Kobayashi M、Ozawa T、Morishita i、Bessho Y、Maeda S、Ledin J、Aburatani H、Kageyama R、Maruyama K、Heldin C-H、Miyazono K
    • Journal Title

      Science Signaling

      Volume: 12 Issue: 607 Pages: 607-607

    • DOI

      10.1126/scisignal.aay4430

    • NAID

      120006902530

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08192, KAKENHI-PROJECT-19K22433, KAKENHI-PLANNED-17H06326, KAKENHI-PUBLICLY-19H04782, KAKENHI-PROJECT-18H02451, KAKENHI-PROJECT-17K11075, KAKENHI-PROJECT-18K07841
  • [Journal Article] c‐Ski accelerates renal cancer progression by attenuating transforming growth factor β signaling2019

    • Author(s)
      Taguchi Luna、Miyakuni Kosuke、Morishita Yasuyuki、Morikawa Teppei、Fukayama Masashi、Miyazono Kohei、Ehata Shogo
    • Journal Title

      Cancer Science

      Volume: 22 Issue: 6 Pages: 465-475

    • DOI

      10.1111/cas.14018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07684, KAKENHI-PROJECT-15H05774
  • [Journal Article] Fibroblast growth factor signals regulate transforming growth factor-β-induced endothelial-to-myofibroblast transition of tumor endothelial cells via Elk12019

    • Author(s)
      Akatsu Y*, Takahashi N*, Yoshimatsu Y*, Kimuro S, Muramatsu T, Katsura A, Maishi N, Suzuki HI, Inazawa J, Hida K, Miyazono K, Watabe T. (*equal contribution)
    • Journal Title

      Molecular Oncology

      Volume: 13 Issue: 8 Pages: 1706-1724

    • DOI

      10.1002/1878-0261.12504

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07157, KAKENHI-PROJECT-18K09715, KAKENHI-PLANNED-15H05908, KAKENHI-PUBLICLY-18H05092, KAKENHI-PROJECT-18H02688, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-18H02996
  • [Journal Article] Comparative analysis of TTF‐1 binding DNA regions in small‐cell lung cancer and non‐small‐cell lung cancer2019

    • Author(s)
      Hokari Satoshi、Tamura Yusuke、Kaneda Atsushi、Katsura Akihiro、Morikawa Masato、Murai Fumihiko、Ehata Shogo、Tsutsumi Shuichi、Ishikawa Yuichi、Aburatani Hiroyuki、Kikuchi Toshiaki、Miyazono Kohei、Koinuma Daizo
    • Journal Title

      Molecular Oncology

      Volume: 14 Issue: 2 Pages: 277-293

    • DOI

      10.1002/1878-0261.12608

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KT0019, KAKENHI-PROJECT-15H05774
  • [Journal Article] Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition2019

    • Author(s)
      Katsuno Yoko、Meyer Dominique Stephan、Zhang Ziyang、Shokat Kevan M.、Akhurst Rosemary J.、Miyazono Kohei、Derynck Rik
    • Journal Title

      Science Signaling

      Volume: 12 Issue: 570

    • DOI

      10.1126/scisignal.aau8544

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Journal Article] Long noncoding RNA NORAD regulates transforming growth factor-β signaling and epithelial-to-mesenchymal transition-like phenotype2018

    • Author(s)
      Kawasaki Natsumi、Miwa Toshiki、Hokari Satoshi、Sakurai Tsubasa、Ohmori Kazuho、Miyauchi Kensuke、Miyazono Kohei、Koinuma Daizo
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 7 Pages: 2211-2220

    • DOI

      10.1111/cas.13626

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Journal Article] Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents.2018

    • Author(s)
      Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T, Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A, Ueda HR.
    • Journal Title

      Cell Rep.

      Volume: 24 Issue: 8 Pages: 2196-2210

    • DOI

      10.1016/j.celrep.2018.07.056

    • NAID

      120006542018

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19373, KAKENHI-PROJECT-18K19419, KAKENHI-PROJECT-18K14915, KAKENHI-PUBLICLY-17H05680, KAKENHI-PUBLICLY-17H05688, KAKENHI-PUBLICLY-17H05735, KAKENHI-PLANNED-17H06328, KAKENHI-PUBLICLY-18H04543, KAKENHI-PUBLICLY-18H04937, KAKENHI-ORGANIZER-18H05428, KAKENHI-PLANNED-18H05433, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26221003, KAKENHI-PROJECT-15H03123, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02545, KAKENHI-PROJECT-15H05650, KAKENHI-PROJECT-16J05041, KAKENHI-PROJECT-17K19438, KAKENHI-PROJECT-25221304, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-17H06326
  • [Journal Article] Decreased TGFBR3/betaglycan expression enhances the metastatic abilities of renal cell carcinoma cells through TGF-β-dependent and -independent mechanisms2018

    • Author(s)
      Nishida J, Miyazono K, Ehata S.
    • Journal Title

      Oncogene

      Volume: 37 Issue: 16 Pages: 2197-2212

    • DOI

      10.1038/s41388-017-0084-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16J05993
  • [Journal Article] Intracellular and extracellular TGF-β signaling in cancer: some recent topics.2018

    • Author(s)
      Kohei Miyazono, Yoko Katsuno, Daizo Koinuma, Shogo Ehata, Masato Morikawa
    • Journal Title

      Frontiers of Medicine

      Volume: 12 Issue: 4 Pages: 387-411

    • DOI

      10.1007/s11684-018-0646-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326
  • [Journal Article] Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells2018

    • Author(s)
      Takahashi K, Ehata S, Koinuma D, Morishita Y, Soda M, Mano H, Miyazono K.
    • Journal Title

      Oncogene

      Volume: - Issue: 21 Pages: 2757-2772

    • DOI

      10.1038/s41388-018-0144-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-15H05774
  • [Journal Article] Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer2017

    • Author(s)
      Yokoyama Y, Watanabe T, Tamura Y, Hashizume Y, Miyazono K, Ehata S.
    • Journal Title

      Cancer Research

      Volume: 77 Issue: 15 Pages: 4026-4038

    • DOI

      10.1158/0008-5472.can-17-0112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-15K08393
  • [Journal Article] Regulation of TGF-β Family Signaling by Inhibitory Smads2017

    • Author(s)
      Miyazawa K, Miyazono K.
    • Journal Title

      Cold Spring Harb Perspect Biol.

      Volume: 9 Issue: 3 Pages: a022095-a022095

    • DOI

      10.1101/cshperspect.a022095

    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Journal Article] Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells2017

    • Author(s)
      Arase M, Tamura Y, Kawasaki N, Isogaya K, Nakaki R, Mizutani A, Tsutsumi S, Aburatani H, Miyazono K, Koinuma D.
    • Journal Title

      Scientific Reports

      Volume: --

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Journal Article] ZEB1-regulated inflammatory phenotype in breast cancer cells2017

    • Author(s)
      Katsura A, Tamura Y, Hokari S, Harada M, Morikawa M, Sakurai T, Takahashi K, Mizutani A, Nishida J, Yokoyama Y, Morishita Y, Murakami T, Ehata S, Miyazono K, Koinuma D
    • Journal Title

      Molecular oncology

      Volume: 11 Issue: 9 Pages: 1241-1262

    • DOI

      10.1002/1878-0261.12098

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K21045, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-26461700
  • [Journal Article] ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.2017

    • Author(s)
      Kamiyama, M., Shirai, T., Tamura, S., Suzuki-Inoue, K., Ehata, S., Takahashi, K., Miyazono, K., Hayakawa, Y., Sato, T., Takeda, K., Naguro, I., Ichijo, H.
    • Journal Title

      Cell Death and Differentiation

      Volume: 24 Issue: 12 Pages: 2066-2076

    • DOI

      10.1038/cdd.2017.114

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K19768, KAKENHI-PUBLICLY-17H05511, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-25221302, KAKENHI-PROJECT-15H04643, KAKENHI-PROJECT-17H05073, KAKENHI-PROJECT-16K15115, KAKENHI-PLANNED-26114009
  • [Journal Article] Regulation of TGF-β-mediated endothelial-mesenchymal transition by microRNA-272017

    • Author(s)
      Suzuki HI, Katsura A, Mihira H, Horie M, Saito A, Miyazono K.
    • Journal Title

      J Biochem.

      Volume: -- Issue: 5 Pages: 417-420

    • DOI

      10.1093/jb/mvx017

    • NAID

      40021219791

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-26461185
  • [Journal Article] Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution2017

    • Author(s)
      Kubota Shimpei I.、Takahashi Kei、Nishida Jun、Morishita Yasuyuki、Ehata Shogo、Tainaka Kazuki、Miyazono Kohei、Ueda Hiroki R.
    • Journal Title

      Cell Reports

      Volume: 20 Issue: 1 Pages: 236-250

    • DOI

      10.1016/j.celrep.2017.06.010

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05688, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-25221004, KAKENHI-PROJECT-16J05993, KAKENHI-PROJECT-17J30007, KAKENHI-PROJECT-15K08393, KAKENHI-PROJECT-16K15124
  • [Journal Article] Dual targeting of vascular endothelial growth factor and bone morphogenetic protein-9/10 impairs tumor growth through inhibition of angiogenesis2017

    • Author(s)
      Akatsu Y, Yoshimatsu Y, Tomizawa T, Takahashi K, Katsura A, Miyazono K, Watabe T.
    • Journal Title

      Cancer Sci.

      Volume: 108 Issue: 1 Pages: 151-155

    • DOI

      10.1111/cas.13103

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-25460473, KAKENHI-PROJECT-15K21394, KAKENHI-PROJECT-16K08614
  • [Journal Article] Mechanisms of action of bone morphogenetic proteins in cancer2016

    • Author(s)
      Davis H, Raja E, Miyazono K, Tsubakihara Y, Moustakas A.
    • Journal Title

      Cytokine Growth Factor Rev.

      Volume: 27 Pages: 81-92

    • DOI

      10.1016/j.cytogfr.2015.11.009

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-24390070, KAKENHI-PROJECT-15H05774
  • [Journal Article] TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology2016

    • Author(s)
      Morikawa M, Derynck R, Miyazono K.
    • Journal Title

      Cold Spring Harb Perspect Biol.

      Volume: 8 Issue: 5 Pages: a021873-a021873

    • DOI

      10.1101/cshperspect.a021873

    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Journal Article] BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Kruppel-like Factors.2016

    • Author(s)
      Morikawa M, Koinuma D, Mizutani A, Kawasaki N, Holmborn K, Sundqvist A, Tsutsumi S, Watabe T, Aburatani H, Heldin CH, Miyazono K.
    • Journal Title

      Stem Cell Reports.

      Volume: 6 Issue: 1 Pages: 64-73

    • DOI

      10.1016/j.stemcr.2015.12.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24390070
  • [Journal Article] Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program2016

    • Author(s)
      Vasilaki E, Morikawa M, Koinuma D, Mizutani A, Hirano Y, Ehata S, Sundqvist A, Kawasaki N, Cedervall J, Olsson AK, Aburatani H, Moustakas A, Miyazono K, Heldin CH.
    • Journal Title

      Sci Signal.

      Volume: 9 Issue: 442

    • DOI

      10.1126/scisignal.aag3232

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15K08393
  • [Journal Article] Mutational Landscape and Antiproliferative Functions of ELF Transcription Factors in Human Cancer2016

    • Author(s)
      Ando M, Kawazu M, Ueno T, Koinuma D, Ando K, Koya J, Kataoka K, Yasuda T, Yamaguchi H, Fukumura K, Yamato A, Soda M, Sai E, Yamashita Y, Asakage T, Miyazaki Y, Kurokawa M, Miyazono K, Nimer SD, Yamasoba T, Mano H.
    • Journal Title

      Cancer Res.

      Volume: 76 Issue: 7 Pages: 1814-1824

    • DOI

      10.1158/0008-5472.can-14-3816

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-26461155, KAKENHI-PROJECT-16K20973
  • [Journal Article] Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release2016

    • Author(s)
      Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardo-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 113 Issue: 7 Pages: 1877-1882

    • DOI

      10.1073/pnas.1525796113

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-15H05774
  • [Journal Article] MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-β2016

    • Author(s)
      Katsura A, Suzuki HI, Ueno T, Mihira H, Yamazaki T, Yasuda T, Watabe T, Mano H, Yamada Y, Miyazono K.
    • Journal Title

      Genes Cells

      Volume: 21 Issue: 1 Pages: 99-116

    • DOI

      10.1111/gtc.12323

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-16K20973
  • [Journal Article] The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinoma2016

    • Author(s)
      Mizutani A, Koinuma D, Seimiya H, Miyazono K.
    • Journal Title

      Oncogene

      Volume: - Issue: 27 Pages: 3514-3523

    • DOI

      10.1038/onc.2015.412

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-26830066, KAKENHI-PROJECT-15H05774
  • [Journal Article] MicroRNA regulons in tumor microenvironment2015

    • Author(s)
      Suzuki HI, Katsura A, Matsuyama H, Miyazono K.
    • Journal Title

      Oncogene

      Volume: 印刷中 Issue: 24 Pages: 3085-3094

    • DOI

      10.1038/onc.2014.254

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002
  • [Journal Article] Smad4 Decreases the Population of Pancreatic Cancer-Initiating Cells through Transcriptional Repression of ALDH1A12015

    • Author(s)
      Hoshino Y, Nishida J, Katsuno Y, Koinuma D, Aoki T, Kokudo N, Miyazono K, Ehata S.
    • Journal Title

      American Journal of Pathology

      Volume: 印刷中 Issue: 5 Pages: 1457-1470

    • DOI

      10.1016/j.ajpath.2015.01.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002
  • [Journal Article] Small-RNA asymmetry is directly driven by mammalian Argonautes2015

    • Author(s)
      Suzuki HI, Katsura A, Yasuda T, Ueno T, Mano H, Sugimoto K, Miyazono K.
    • Journal Title

      Nat Struct Mol Biol.

      Volume: 22 Issue: 7 Pages: 512-521

    • DOI

      10.1038/nsmb.3050

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Journal Article] A role of uridylation pathway for blockade of let-7 microRNA biogenesis by Lin28B2015

    • Author(s)
      Suzuki HI, Katsura A, Miyazono K.
    • Journal Title

      Cancer Sci.

      Volume: 106 Issue: 9 Pages: 1174-1181

    • DOI

      10.1111/cas.12721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Journal Article] Expression of platelet-derived growth factor receptor β is maintained by Prox1 in lymphatic endothelial cells and is required for tumor lymphangiogenesis2014

    • Author(s)
      Miyazaki H, Yoshimatsu Y, Akatsu Y, Mishima K, Fukayama M, Watabe T, Miyazono K.
    • Journal Title

      Cancer Science

      Volume: 105 Issue: 9 Pages: 1116-1123

    • DOI

      10.1111/cas.12476

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PUBLICLY-25122705, KAKENHI-PROJECT-25460473, KAKENHI-PLANNED-22112002
  • [Journal Article] A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression2014

    • Author(s)
      Isogaya K, Koinuma D, Tsutsumi S, Saito RA, Miyazawa K, Aburatani H, Miyazono K.
    • Journal Title

      Cell Research

      Volume: 24 Issue: 8 Pages: 994-1008

    • DOI

      10.1038/cr.2014.97

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-26461185, KAKENHI-PLANNED-22112002
  • [Journal Article] Roles of TGF-β family signals in the fate determination of pluripotent stem cells.2014

    • Author(s)
      Itoh F, Watabe T, Miyazono K.
    • Journal Title

      Seminars in Cell and Developmental Biology

      Volume: 32 Pages: 98-106

    • DOI

      10.1016/j.semcdb.2014.05.017

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PROJECT-24390070, KAKENHI-PUBLICLY-25118728, KAKENHI-PLANNED-22112002
  • [Journal Article] The COUP-TFII variant lacking a DNA-binding domain inhibits the activation of the Cyp7a1 promoter through physical interaction with COUP-TFII2013

    • Author(s)
      Yamazaki T, Suehiro J, Miyazaki H, Minami T, Kodama T, Miyazono K, Watabe T.
    • Journal Title

      Biochemical Journal

      Volume: 452 Issue: 2 Pages: 345-357

    • DOI

      10.1042/bj20121200

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24700969, KAKENHI-PUBLICLY-25122705, KAKENHI-PROJECT-25460473
  • [Journal Article] Bone morphogenetic protein-9 inhibits lymphatic vessel formation via activin receptor-like kinase 1 during development and cancer progression2013

    • Author(s)
      Yoshimatsu Y
    • Journal Title

      Proc. Natl. Acad. Sci. U. S. A.

      Volume: 10 Issue: 47 Pages: 18940-18945

    • DOI

      10.1073/pnas.1310479110

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24689018, KAKENHI-PUBLICLY-25122705, KAKENHI-PROJECT-25460473
  • [Journal Article] Bi-directional roles of bone morphogenetic proteins in cancer : another molecular Jekyll and Hyde?2013

    • Author(s)
      Shogo Ehata, Yuichiro Yokoyama and Kei Takahashi, Kohei Miyazono
    • Journal Title

      Pathology International

      Volume: 63 Issue: 6 Pages: 287-296

    • DOI

      10.1111/pin.12067

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J10991, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24390070, KAKENHI-PROJECT-24700967
  • [Journal Article] Basolateral BMP signaling in polarized epithelial cells2013

    • Author(s)
      Saitoh M, Shirakihara T, Fukasawa A, Horiguchi K, Sakamoto K, Sugiya H, Beppu H, Fujita Y, Morita I, Miyazono K, Miyazawa K.
    • Journal Title

      PLoS One

      Volume: 13 Issue: 5 Pages: 1-10

    • DOI

      10.1371/journal.pone.0062659

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22390059, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-24580433
  • [Journal Article] Genome-wide mechanisms of Smad binding2013

    • Author(s)
      Morikawa M
    • Journal Title

      Oncogene

      Volume: 32 Issue: 13 Pages: 1609-1615

    • DOI

      10.1038/onc.2012.191

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22790750, KAKENHI-PROJECT-24390070, KAKENHI-ORGANIZER-22112001
  • [Journal Article] Report of the Japan Diabetes Society/Japanese Cancer Association joint committee on diabetes and cancer.2013

    • Author(s)
      Kasuga M, Ueki K, Tajima N, Noda M, Ohashi K, Noto H, Goto A, Ogawa W, Sakai R, Tsugane S, Hamajima N, Nakagama H, Tajima K, Miyazono K, Imai K.
    • Journal Title

      Cancer Sci

      Volume: 104(7) Issue: 7 Pages: 965-976

    • DOI

      10.1111/cas.12203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-221S0001
  • [Journal Article] Computational dissection of distinct microRNA activity signatures associated with peripheral T cell lymphoma subtypes2013

    • Author(s)
      Suzuki HI
    • Journal Title

      Leukemia

      Volume: 27 Issue: 10 Pages: 2107-2111

    • DOI

      10.1038/leu.2013.121

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-23591407, KAKENHI-PROJECT-24689018, KAKENHI-PUBLICLY-25118725
  • [Journal Article] Oligodendrocyte transcription factor 1 (Olig1) is a Smad cofactor involved in cell motility induced by transforming growth factor-β2013

    • Author(s)
      Motizuki M, Isogaya K, Miyake K, Ikushima H, Kubota T, Miyazono K, Saitoh M, Miyazawa K.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 288 Issue: 26 Pages: 18911-18922

    • DOI

      10.1074/jbc.m113.480996

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-25860852
  • [Journal Article] Identification of integrin α3 as a molecular marker of cells undergoing epithelial-mesenchymal transition and of cancer cells with aggressive phenotypes.2013

    • Author(s)
      Shirakihara T, Kawasaki T, Fukagawa A, Semba K, Sakai R, Miyazono K, Miyazawa K, Saitoh M.
    • Journal Title

      Cancer Science

      Volume: 104 Issue: 9 Pages: 1189-1197

    • DOI

      10.1111/cas.12220

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-23300353, KAKENHI-PROJECT-24390419, KAKENHI-PROJECT-25830096
  • [Journal Article] Tumor-promoting functions of transforming growth factor-β in progression of cancer2012

    • Author(s)
      Miyazono K
    • Journal Title

      Ups J Med Sci

      Volume: 117 Issue: 2 Pages: 143-152

    • DOI

      10.3109/03009734.2011.638729

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22700876, KAKENHI-PROJECT-24700967
  • [Journal Article] Transforming growth factor-SS decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells.2011

    • Author(s)
      Ehata S, Johansson E, Katayama R, Koike S, Watanabe A, Hoshino Y, Katsuno Y, Komuro A, Koinuma D, Kano MR, Yashiro M, Hirakawa K, Aburatani H, Fujita N, Miyazono K.
    • Journal Title

      Oncogene 30

      Pages: 1693-1705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790380
  • [Journal Article] TGF-β derives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP2011

    • Author(s)
      堀口華奈
    • Journal Title

      Oncogene

      Volume: (掲載確定)(印刷中) Issue: 26 Pages: 3190-3201

    • DOI

      10.1038/onc.2011.493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J05735, KAKENHI-PROJECT-11F01113, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22249061, KAKENHI-PROJECT-22390052, KAKENHI-PROJECT-22790750, KAKENHI-PROJECT-23390202, KAKENHI-PROJECT-23659854
  • [Journal Article] Ets family members induce lymphangiogenesis via physical and functional interaction with Prox12011

    • Author(s)
      Yoshimatsu Y, Mihira H, Itoh T, Yuki K, Harada K, Morikawa M, Yamazaki T, Iwata C, Minami T, Morishita Y, Kodama T, Miyazono K, Watabe T
    • Journal Title

      J Cell Sci. (掲載確定(印刷中))

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Arkadia-beyond the TGF-β pathway2011

    • Author(s)
      Miyazono K, Koinuma D
    • Journal Title

      Journal of Biochemistry

      Volume: 149 Pages: 1-3

    • NAID

      10030582535

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Journal Article] TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition.2011

    • Author(s)
      Shirakihara T, Miyazono K, et al.
    • Journal Title

      EMBO Journal

      Volume: 30 Pages: 783-795

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Journal Article] Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-SS-disrupted diffuse-type gastric carcinoma.2010

    • Author(s)
      Johansson E., Komuro A., Iwata C., Hagiwara A., Fuse Y., Watanabe A., Morishita Y., Aburatani H., Funa K., Kano M.R., Miyazono K.
    • Journal Title

      Cancer Sci. 101

      Pages: 2398-2403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790380
  • [Journal Article] GF-βsignalling: a complex web in cancer progression2010

    • Author(s)
      Ikushima, H., Miyazono, K.
    • Journal Title

      Nature Rev. Cancer 10(6)

      Pages: 415-424

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Cellular context-dependent "colors" of transforming growth factor-βsignaling.2010

    • Author(s)
      Ikushima, H., Miyazono, K.
    • Journal Title

      Cancer Sci. 101(2)

      Pages: 306-312

    • NAID

      10026587361

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox12010

    • Author(s)
      Flister MJ, Wilber A, Hall KL, Iwata C, Miyazono K, Nisato RE, Pepper MS, Zawieja DC, Ran S
    • Journal Title

      Blood 115(2)

      Pages: 418-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] TGF-beta signalling : a complex web in cancer progression2010

    • Author(s)
      Ikushima H, Miyazono K
    • Journal Title

      Nature Reviews Cancer

      Volume: 10 Pages: 415-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Journal Article] BMP-9 induces proliferation of multiple types of endothelial cells in vitro and in vivo.2010

    • Author(s)
      Suzuki Y, Ohga N, Morishita Y, Hida K, Miyazono K, Watabe T
    • Journal Title

      J Cell Sci. 123(10)

      Pages: 1684-1692

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-beta-disrupted diffuse-type gastric carcinoma2010

    • Author(s)
      Johansson E, Komuro A, Iwata C, Hagiwara A, Fuse Y, Watanabe A, Morishita Y, Aburatani H, Funa K, Kano MR, Miyazono K
    • Journal Title

      Cancer Sci

      Volume: 10 Pages: 2398-2403

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790380
  • [Journal Article] LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis.2010

    • Author(s)
      Sumida H, Noguchi K, Kihara Y, Abe M, Yanagida K, Hamano F, Sato S, Tamaki K, Morishita Y, Kano MR, Iwata C, Miyazono K, Sakimura K, Shimizu T, Ishii S.
    • Journal Title

      Blood. 116(23)

      Pages: 5060-5070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Bone morphogenetic protein receptors and signal transduction2010

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Journal of Biochemistry 147

      Pages: 35-51

    • NAID

      10027873043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Dynamics of microRNA biogenesis : crosstalk between p53 network and microRNA processing pathway2010

    • Author(s)
      Suzuki HI, Miyazono K
    • Journal Title

      Journal of Molecular Medicine

      Volume: 88 Pages: 1085-1094

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Journal Article] Cellular context-dependent "colors" of transforming growth factor-β signaling2010

    • Author(s)
      Ikushima, H., Miyazono, K.
    • Journal Title

      Cancer Science 100

      Pages: 306-312

    • NAID

      10026587361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells.2010

    • Author(s)
      Nagano, Y., Koinuma, D., Miyazawa, K., Miyazono, K.
    • Journal Title

      J. Biochem. 147(4)

      Pages: 545-554

    • NAID

      10027875176

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] TGFβ signalling : a complex web in cancer progression2010

    • Author(s)
      Ikushima H, Miyazono K
    • Journal Title

      Nature Reviews Cancer 10

      Pages: 415-424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22220013
  • [Journal Article] Bone morphogenetic protein receptors and signal transduction.2010

    • Author(s)
      Miyazono, K., Kamiya, Y., Morikawa, M.
    • Journal Title

      J. Biochem. 147(1)

      Pages: 35-51

    • NAID

      10027873043

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1.2010

    • Author(s)
      Flister MJ, Wilber A, Hall KL, Iwata C, Miyazono K, Nisato RE, Pepper MS, Zawieja DC, Ran S
    • Journal Title

      Blood. 115(2)

      Pages: 418-429

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction.2009

    • Author(s)
      Yamazaki T, Yoshimatsu Y, Morishita Y, Miyazono K, Watabe T
    • Journal Title

      Genes Cells 14(3)

      Pages: 425-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Comparison of the effects of the kinase inhibitors imatinib, sorafenib, and transforming growth factor-βreceptor inhibitor on extravasation of nanoparticles from neovasculature.2009

    • Author(s)
      Kano, M.R., Komuta, Y., Iwata, C., Oka, M., Shirai, Y., Morishita, Y., Ouchi, Y., Kataoka, K., Miyazono, K.
    • Journal Title

      Cancer Sci. 100(1)

      Pages: 173-180

    • NAID

      10025141855

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Role of Ras signaling in the induction of snail by transforming growth factor-β.2009

    • Author(s)
      Horiguchi, K., Shirakihara, T., Nakano, A., Imamura, T., Miyazono, K., Saitoh, M.
    • Journal Title

      J. Biol. Chem. 284(1)

      Pages: 245-253

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Autocrine TGF-βsignaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors.2009

    • Author(s)
      Ikushima, H., Todo, T., Ino, Y., Takahashi, M., Miyazawa, K., Miyazono, K.
    • Journal Title

      Cell Stem Cell 5(5)

      Pages: 504-514

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] VEGFR2-PLCgamma1 axis is essential for endothelial specification of VEGFR2+ vascular progenitor cells.2009

    • Author(s)
      Sase H, Watabe T, Kawasaki K, Miyazono K, Miyazawa K
    • Journal Title

      J Cell Sci. 122(18)

      Pages: 3303-3311

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Promoter-wide analysis of Smad4 binding sites in human epithelial cells.2009

    • Author(s)
      Koinuma, D., Tsutsumi, S., Kamimura, N., Imamura, T., Aburatani, H., Miyazono, K.
    • Journal Title

      Cancer Sci. 100(11)

      Pages: 2133-2142

    • NAID

      10027197070

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Transforming growth factor-β signaling in epithelial-mesenchymal transition and progression of cancer2009

    • Author(s)
      Miyazono, K.
    • Journal Title

      Proc Jpn Acad Ser B Phys Biol Sci. 85

      Pages: 314-323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction2009

    • Author(s)
      Yamazaki T, Yoshimatsu Y, Morishita Y, Miyazono K, Watabe T
    • Journal Title

      Genes Cells 14(3)

      Pages: 425-434

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Thyroid transcription factor-1 inhibits transforming growth factor- β- mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.2009

    • Author(s)
      Saito, R.A., Watabe, T., Horiguchi, K., Kohyama, T., Saitoh, M., Nagase, T., Miyazono, K.
    • Journal Title

      Cancer Res. 69(7)

      Pages: 2783-2791

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Autophagy is activated by TGF-βand potentiates TGF- β-mediated growth inhibition in human hepatocellular carcinoma cells.2009

    • Author(s)
      Kiyono, K., Suzuki, H.I., Matsuyama, H., Morishita, Y., Komuro, A., Kano, M.R., Sugimoto, K., Miyazono, K.
    • Journal Title

      Cancer Res. 69(23)

      Pages: 8844-8852

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Diffuse-type gastric carcinoma: Progression, angiogenesis, and transforming growth factor-βsignaling.2009

    • Author(s)
      Komuro, A., Yashiro, M., Iwata, C., Morishita, Y., Johansson, E., Matsumoto, Y., Watanabe, A., Aburatani, H., Miyoshi, H., Kiyono, K., Shirai, Y., Suzuki, H.I., Hirakawa, K., Kano, M.R., Miyazono, K.
    • Journal Title

      J. Natl. Cancer Inst. 101(8)

      Pages: 592-604

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Identification of Prox1 targets during in vitro vascular differentiation from embryonic stem cells : functional roles of HoxD8 in lymphangiogenesis2009

    • Author(s)
      Harada K, Yamazaki T, Iwata C, Yoshimatsu Y, Sase H, Mishima K, Morishita Y, Hirashima M, Oike Y, Suda T, Miura N, Watabe T, Miyazono K
    • Journal Title

      J Cell Sci. 122(21)

      Pages: 3923-3930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] SKI and MEL1 cooperate to inhibit transforming growth factor-βsignal in gastric cancer cells.2009

    • Author(s)
      Takahata, M., Inoue, Y., Tsuda, H., Imoto, I., Koinuma, D., Hayashi, M., Ichikura, T., Yamori, T., Nagasaki, K., Yoshida, M., Matsuoka, M., Morishita, K., Yuki, K., Hanyu, A., Miyazawa, K., Inazawa, J., Miyazono, K., Imamura T.
    • Journal Title

      J. Biol. Chem. 284(5)

      Pages: 3334-3344

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Identification of Prox1 targets during in vitro vascular differentiation from embryonic stem cells : functional roles of HoxD8 in lymphangiogenesis.2009

    • Author(s)
      Harada K, Yamazaki T, Iwata C, Yoshimatsu Y, Sase H, Mishima K, Morishita Y, Hirashima M, Oike Y, Suda T, Miura N, Watabe T, Miyazono K
    • Journal Title

      J Cell Sci. 122(21)

      Pages: 3923-3930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] c-Ski overexpression promotes tumor growth and angiogenesis through inhibition of transforming growth factor-βsignaling in diffuse-type gastric carcinoma.2009

    • Author(s)
      Kiyono, K., Suzuki, H.I., Morishita, Y., Komuro, A., Iwata, C., Yashiro, M., Hirakawa, K., Kano, M.R., Miyazono, K.
    • Journal Title

      Cancer Sci. 100(10)

      Pages: 1809-1816

    • NAID

      10027195355

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factorβsignaling.2009

    • Author(s)
      Koinuma, D., Tsutsumi, S., Kamimura, N., Taniguchi, H., Miyazawa, K., Sunamura, M., Imamura, T., Miyazono, K., Aburatani, H.
    • Journal Title

      Mol. Cell. Biol. 29(1)

      Pages: 172-186

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Modulation of microRNA processing by p53.2009

    • Author(s)
      Suzuki, H.I., Yamagata, K., Sugimoto, K., Iwamoto, T., Kato, S., Miyazono, K.
    • Journal Title

      Nature 460(7254)

      Pages: 529-533

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] SUMO amplifies TGF-beta signalling2008

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Nat Cell Biol. 10

      Pages: 635-637

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-βsignaling.2008

    • Author(s)
      Ikushima, H., Komuro, A., Isogaya, K., Shinozaki, M., Hellman, U., Miyazawa, K., Miyazono, K.
    • Journal Title

      EMBO J. 27(22)

      Pages: 2955-2965

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-b signaling.2008

    • Author(s)
      Ikushima H. Komuro A, IsogayaK, Shinozaki M, Hellman U, Miyazawa K, Miyazono K.
    • Journal Title

      EMBO J 27

      Pages: 2955-2965

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17012024
  • [Journal Article] Snail is required for TGF- β-induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells.2008

    • Author(s)
      Kokudo, T., Suzuki, Y., Yoshimatsu, Y., Yamazaki, T., Watabe, T., Miyazono, K.
    • Journal Title

      J. Cell Sci. 121(20)

      Pages: 3317-3324

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.2008

    • Author(s)
      Katsuno, Y., Hanyu, A., Kanda, H., Ishikawa, Y., Akiyama, F., Iwase, T., Ogata, E., Ehata, S., Miyazono, K., Imamura, T.
    • Journal Title

      Oncogene 27(49)

      Pages: 6322-6333

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis2008

    • Author(s)
      Oka M, Iwata C, Suzuki HI, Kiyono K, Morishita Y, Watabe T, Komuro A, Kano MR, Miyazono K
    • Journal Title

      Blood 111(9)

      Pages: 4571-4579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Inhibition of endogenous TGF-βsignaling enhances lymphangiogenesis.2008

    • Author(s)
      Oka, M., Iwata, C., Suzuki, H.I., Kiyono, K., Morishita, Y., Watabe, T., Komuro, A., Kano, M.R., Miyazono, K.
    • Journal Title

      Blood 111(9)

      Pages: 4571-4579

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Shear activates platelet-derived latent TGF-beta2008

    • Author(s)
      Miyazono, K.
    • Journal Title

      Blood 112

      Pages: 3533-3534

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inhibition of endogenous TGF-beta signaling enhances lymphangiogenesis.2008

    • Author(s)
      Oka M, Iwata C, Suzuki HI, Kiyono K, Morishita Y, Watabe T, Komuro A, Kano MR, Miyazono K
    • Journal Title

      Blood. 111(9)

      Pages: 4571-4579

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Arkadia induces degradation of SnoN and c-Ski to enhance TGF-βsignaling.2007

    • Author(s)
      Nagano, Y., Mavrakis, K.J., Lee, K.L., Fujii, T., Koinuma, D., Sase, H., Yuki, K., Isogaya, K., Saitoh, M., Imamura, T., Episkopou, V., Miyazono, K., Miyazawa, K.
    • Journal Title

      J. Biol. Chem. 282(28)

      Pages: 20492-20501

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Modulation of the functional binding sites for TGF-βon the type II receptor leads to suppression of TGF-βsignaling.2007

    • Author(s)
      Shimanuki, T., Hara, T., Furuya, T., Imamura, T., Miyazono, K.
    • Journal Title

      Oncogene 26(23)

      Pages: 3311-3320

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis2007

    • Author(s)
      Iwata C, Kano MR, Komuro A, Oka M, Kiyono K, Johansson E, Morishita Y, Yashiro M, Hirakawa K, Kaminishi M, Miyazono K
    • Journal Title

      Cancer Res. 67(21)

      Pages: 10181-101819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Ki26894, a novel transforming growth factor-βtype I receptor kinase inhibitor, inhibits in vitro cell motility and invasion and in vivo bone metastasis of a human breast cancer cell line.2007

    • Author(s)
      Ehata, S., Hanyu, A., Katsuno, Y., Fukunaga, E., Goto, K., Ishikawa, Y., Nomura, K., Ogata, E., Fujime, M., Miyazono, K., Shimizu, K., Imamura, T.
    • Journal Title

      Cancer Sci. 98(1)

      Pages: 127-133

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis.2007

    • Author(s)
      Iwata C, Kano MR, Komuro A, Oka M, Kiyono K, Johansson E, Morishita Y, Yashiro M, Hirakawa K, Kaminishi M, Miyazono K
    • Journal Title

      Cancer Res. 67(21)

      Pages: 10181-10189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Journal Article] Differential regulation of epithelial and mesenchymal markers byδEF1 proteins in epithelial mesenchymal transition induced by TGF-β.2007

    • Author(s)
      Shirakihara, T., Saitoh, M., Miyazono K.
    • Journal Title

      Mol. Biol. Cell 18(9)

      Pages: 3533-3544

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Transforming growth factor-βpromotes survival of mammary carcinoma cells through induction of anti-apoptotic transcription factor DEC1.2007

    • Author(s)
      Ehata, S., Hanyu, A., Hayashi, M., Aburatani, H., Kato, Y., Fujime, M., Saitoh, M., Miyazawa, K., Imamura, T., Miyazono, K.
    • Journal Title

      Cancer Res. 67(20)

      Pages: 9694-9703

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptors.2007

    • Author(s)
      Goto, K., Kamiya, Y., Imamura, T., Miyazono, K., Miyazawa, K.
    • Journal Title

      J. Biol. Chem. 282(28)

      Pages: 20603-20611

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Improvement of cancer-targeting therapy using nanocarriers for intractable solid tumors by inhibition of TGF-βsignalling. Proc.2007

    • Author(s)
      Kano, M.R., Bae, Y., Iwata, C., Morishita, Y., Yashiro, M., Oka, M., Fujii, T., Komuro, A., Kiyono, K., Kaminishi, M., Hirakawa, K., Ouchi, Y., Nishiyama, N., Kataoka, K., Miyazono, K.
    • Journal Title

      Natl. Acad. Sci. USA 104(9)

      Pages: 3460-3465

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling.2007

    • Author(s)
      Kano, MR., Miyazono, K., et al.
    • Journal Title

      Proc Natl Acad Sci USA. 104(9)

      Pages: 3460-3465

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] Nuclear and cytoplasmic c-Ski differentially modulate cellular functions.2006

    • Author(s)
      Nagata, M., Goto, K., Ehata, S., Kobayashi, N., Saitoh, M., Miyoshi, H., Imamura, T., Miyazawa, K., Miyazono, K.
    • Journal Title

      Genes Cells 11(11)

      Pages: 1267-1280

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Execution of BMP-4- induced apoptosis by p53-dependent ER dysfunction in myeloma and B-cell hybridoma cells.2006

    • Author(s)
      Fukuda, N., Saitoh, M., Kobayashi, N., Miyazono, K.
    • Journal Title

      Oncogene 25(25)

      Pages: 3509-3517

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] The ALK-5 Inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-β.2005

    • Author(s)
      Tojo, M., Hamashima, Y., Hanyu, A., Kajimoto, T., Saitoh, M., Miyazono, K., Node, M., Imamura, T.
    • Journal Title

      Cancer Sci. 96(11)

      Pages: 791-800

    • NAID

      10017091727

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] BMP receptor signaling : transcriptional targets, regulation of signals, and signaling cross-talk2005

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Cytokine and Growth Factor Reviews 16(3)

      Pages: 251-263

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] BMP receptor signaling : transcriptional targets, regulation of signals, and signaling cross-talk2005

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Cytokine Growth Factor Rev. 16・3

      Pages: 251-263

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.2005

    • Author(s)
      Azuma, H., Ehata, S., Miyazaki, H., Watabe, T., Maruyama, O., Imamura, T., Sakamoto, T., Kiyama, S., Kiyama, Y., Ubai, T., Inamoto, T., Takahara, S., Itoh, Y., Otsuki, Y., Katsuoka, Y., Miyazono, K., Horie, S.
    • Journal Title

      J. Natl. Cancer Inst. 97(23)

      Pages: 1734-1746

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] Effect of smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.2005

    • Author(s)
      Azuma, H., Miyazono, K., et al.
    • Journal Title

      J.Natl.Cancer Inst. 97(23)

      Pages: 1734-1746

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] BMP receptor signaling : transcriptional targets, regulation of signals, and signaling cross-talk2005

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Cytokine Growth Factor Rev. 16・3

      Pages: 251-263

    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.2005

    • Author(s)
      Azuma H, Ehata S, Miyazaki H, Watabe T, Miyazono K. et al.
    • Journal Title

      J.Natl.Cancer Inst 97・23

      Pages: 1734-1746

    • Data Source
      KAKENHI-PROJECT-17012024
  • [Journal Article] VEGF-A and FGF-2 synergistically promote neoangiogenesis through enhancement of endogenous PDGF-B/PDGFRβsignaling.2005

    • Author(s)
      Kano, M.R., Morishita, Y., Iwata, C., Iwasaka, S., Watabe, T., Ouchi, Y., Miyazono, K., Miyazawa, K.
    • Journal Title

      J. Cell Sci. 118(16)

      Pages: 3759-3768

    • Data Source
      KAKENHI-PROJECT-17016011
  • [Journal Article] The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta.2005

    • Author(s)
      Tojo M, Hamashima Y, Hanyu A, Kajimoto T, Saitoh M, Miyazono K, Node M, Imamura T.
    • Journal Title

      Cancer Sci 96

      Pages: 791-800

    • Data Source
      KAKENHI-PROJECT-17012024
  • [Journal Article] BMP receptor signaling : transcriptional targets, regulation of signals, and signaling cross-talk2005

    • Author(s)
      Miyazono K, et al.
    • Journal Title

      Cytokine and Growth Factor Reviews 16・3

      Pages: 251-263

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins2004

    • Author(s)
      Miyazono K, et al.
    • Journal Title

      Oncogene 23・24

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23・24

      Pages: 4232-4237

    • Data Source
      KAKENHI-PROJECT-12219217
  • [Journal Article] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor- β superfamily signaling.2004

    • Author(s)
      Mochizuki, T., Miyazaki, H., Hara, T., Furuya, T., Imamura, T., Watabe, T., Miyazono, K.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 31568-31574

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-11182101
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-β super-family and Runx proteins2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23・24

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12219217
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23・24

      Pages: 4232-4237

    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23(24)

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14208087
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-β superfamily and Runx proteins.2004

    • Author(s)
      Miyazono, K., et al.
    • Journal Title

      Oncogene 23 (24)

      Pages: 4232-4237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12219217
  • [Journal Article] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-β superfamily signaling.2004

    • Author(s)
      Mochizuki, T., Miyazaki, H., Hara, T., Furuya, T., Imamura, T., Watabe, T., Miyazono, K.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 31567-31574

    • Data Source
      KAKENHI-PROJECT-11182101
  • [Journal Article] Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-β superfamily signaling.2004

    • Author(s)
      Mochizuki, T., Miyazaki, H., Hara, T., Furuya, T., Imamura, T., Watabe, T., Miyazono, K.
    • Journal Title

      J. Biol. Chem 279

      Pages: 31568-31574

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-11182101
  • [Journal Article] Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins.2004

    • Author(s)
      Miyazono, K. et al.
    • Journal Title

      Oncogene 23

      Pages: 4232-4237

    • Data Source
      KAKENHI-PROJECT-16062101
  • [Journal Article] A homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells.

    • Author(s)
      Watanabe A., Ogiwara H., Ehata S., Mukasa A., Ishikawa S., Maeda D., Ueki K., Ino Y., Todo T., Yamada Y., Fukayama M., Miyazono K., Aburatani H.
    • Journal Title

      Proc.Natl.Acad.Sci.U.S.A. (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790380
  • [Patent] 新規なHVEM結合タンパク質およびそれを含む医薬組成物2023

    • Inventor(s)
      宮園浩平、田邉諒、他4名
    • Industrial Property Rights Holder
      東京大学、理化学研究所
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-131057
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-23H05486
  • [Patent] 神経膠腫の治療および予防剤、脳腫瘍の悪性度のマーカーおよび脳腫瘍の予後 マーカー並びに脳腫瘍の悪性度および予後の判定方法並びに腫瘍増殖を抑制する抗体2019

    • Inventor(s)
      宮園浩平、他5名
    • Industrial Property Rights Holder
      宮園浩平、他5名
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Overseas
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Patent] 神経膠腫の治療および予防剤、脳腫瘍の悪性度のマーカーおよび脳腫瘍の予後マーカー並びに脳腫瘍の悪性度および予後の判定方法2018

    • Inventor(s)
      宮園浩平、他5名
    • Industrial Property Rights Holder
      宮園浩平、他5名
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Patent] TGFβ阻害機能を持つキメラタンパク質2014

    • Inventor(s)
      渡部徹郎、宮園浩平、鯉沼代造、江幡正悟、 赤津裕一
    • Industrial Property Rights Holder
      日本化薬株式会社、国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-08-11
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Patent] 癌の予後を予測するための方法及びキット、癌治療薬のスクリーニング方法、癌細胞増殖抑制剤、並びに癌治療薬2014

    • Inventor(s)
      宮園浩平、鯉沼代造、磯谷一暢 、川﨑夏実
    • Industrial Property Rights Holder
      国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-04-24
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Patent] 血管新生因子と結合するキメラタンパク質2014

    • Inventor(s)
      宮園浩平、渡部徹郎、赤津裕一
    • Industrial Property Rights Holder
      日本化薬株式会社、国立大学法人東京大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-08-11
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Patent] グリオーマ幹細胞の分化促進剤2010

    • Inventor(s)
      宮園浩平, 他
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2010-02-10
    • Overseas
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Patent] グリオーマ幹細胞の分化促進剤2010

    • Inventor(s)
      宮園浩平、生島弘彬、宮澤恵二, 他
    • Industrial Property Rights Holder
      東京大学
    • Filing Date
      2010-02-10
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Patent] TGF-βシグナル阻害剤と抗腫瘍剤の組合せ使用2006

    • Inventor(s)
      宮園浩平、片岡一則、狩野光伸、べーユンスー、西山伸宏、平川弘聖、八代正和、野出學
    • Industrial Property Rights Holder
      東京大学
    • Acquisition Date
      2006-02-01
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Patent] TGF-βシグナル阻害剤と抗腫瘍剤の組み合せ使用2006

    • Inventor(s)
      宮園浩平 他7名
    • Industrial Property Number
      2006-024843
    • Filing Date
      2006-02-01
    • Data Source
      KAKENHI-PROJECT-17012024
  • [Patent] TGF-βシダナル阻害剤と抗腫瘍剤の組み合せ使用2006

    • Inventor(s)
      宮園浩平他7名
    • Industrial Property Rights Holder
      科学技術振興機構
    • Industrial Property Number
      2006-024843
    • Filing Date
      2006-02-01
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] BMPーその多彩な作用と疾患との関連(特別講演)2023

    • Author(s)
      宮園浩平
    • Organizer
      第41回日本骨代謝学会学術集会(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H05486
  • [Presentation] HVEM as a molecular target of glioblastoma2023

    • Author(s)
      Miyazono Kohei, Tanabe Ryo, Matsumoto Takehisa
    • Organizer
      TGFβ meeting (Uppsala, Sweden)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23H05486
  • [Presentation] Encounter of Cancer Research and Molecular Biology(特別シンポジウム)2023

    • Author(s)
      Miyazono Kohei
    • Organizer
      第82回日本癌学会学術総会(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H05486
  • [Presentation] TGF-β-induced cell cycle arrest is correlated with increased migration and metastasis of oral squamous carcinoma cells(口演)2023

    • Author(s)
      Inoue KA, Takahashi K, Saito M, Sakakitani S, Konishi T, Koinuma D, Sugauchi A, Kaida A, Yoshimatsu Y, Uchihashi T, Miura M, Miyazono K, Watabe T.
    • Organizer
      第46回日本リンパ学会総会(東京)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] BMPシグナルの脳腫瘍幹細胞への多彩な作用(特別講演)2023

    • Author(s)
      宮園浩平
    • Organizer
      第41回日本脳腫瘍学会学術集会 (新潟)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23H05486
  • [Presentation] Plasticity of cancer cells and mechanisms of TGF-β-induced cancer metastasis2022

    • Author(s)
      Miyazono K.
    • Organizer
      第81回日本癌学会学術総会(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] トリプルネガティブ乳がん細胞におけるPolyI:CによるTGF-βシグナル抑制を介したパイロトーシス誘導及び細胞増殖抑制機構 (口演)2022

    • Author(s)
      鯉沼代造、田村佑介、森川真大、堤修一、田邉諒、宮園浩平
    • Organizer
      第81回日本癌学会学術総会(横浜)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-β signaling in progression of cancer2022

    • Author(s)
      Miyazono K.
    • Organizer
      The 10th Sweden-Japan Academic Network Seminar (Stockholm, Sweden)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Multiple roles of TGF-β signaling in cancer metastasis2022

    • Author(s)
      Miyazono K.
    • Organizer
      FASEB Science Research Conferences 2022 - The TGF-β Superfamily Conference: Signaling in Development and Disease (Malahide, Ireland)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice (Poster)2022

    • Author(s)
      Morikawa M, Ozawa TA, Miyazono K.
    • Organizer
      2nd Annual TGF-β for Immuno-Oncology Drug Development Summit (online) 2022年
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Identification of the mechanisms of malignant progression of triple-negative breast cancer via epigenetic changes (Oral/Poster)2022

    • Author(s)
      Ogikubo K, Nishida J, Takahashi K, Morikawa M, Ehata S, Koinuma D, Miyazono K.
    • Organizer
      第81回日本癌学会学術総会(横浜)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βは増殖が低下して運動能が上昇したがん細胞集団を形成することで口腔がんの転移を亢進する (特別シンポジウム1「がん研究における女性研究者」)2022

    • Author(s)
      井上カタジナアンナ、高橋和樹、須河内昭成、飯田渓太、岩渕禎弘、鯉沼代造、栗岡恭子、小西徹、田中普、戒田篤志、三浦雅彦、橋本真一、岡田眞里子、内橋俊大、宮園浩平、渡部徹郎
    • Organizer
      第81回日本癌学会学術総会(横浜)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βによる血管・リンパ管新生の制御と可視化2022

    • Author(s)
      宮園浩平
    • Organizer
      第46回日本リンパ学会総会(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Identification of genes and their regulatory mechanisms associated with high malignancy of triple-negative breast cancer(ポスター)2022

    • Author(s)
      Ogikubo K, Nishida J, Takahashi K, Morikawa M, Ehata S, Koinuma D, Miyazono K.
    • Organizer
      12th AACR-JCA Joint Conference: Breakthrough in Cancer Research : Translating Knowledge into Practice (Maui, U.S.A.)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βファミリーを標的としたがん治療戦略(教育講演)2021

    • Author(s)
      宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 腎細胞がんはDNAメチル化を介してアポトーシス耐性を獲得する(口演)2021

    • Author(s)
      宮國昂介、西田純、鯉沼代造、江幡正悟、宮園浩平
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 組織透明化のがん研究への応用(シンポジウム)2021

    • Author(s)
      高橋恵生、宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 三次元病理解析に資する組織透明化手法の開発2021

    • Author(s)
      久保田晋平、高橋恵生、田井中一貴、江幡正悟、上田泰己、宮園浩平
    • Organizer
      第110回日本病理学会総会(東京、online)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 組織透明化によるがん微小環境リモデリングの解析 (口演)2021

    • Author(s)
      久保田晋平、高橋恵生、真野智之、松本桂彦、勝俣敬寛、史蕭逸、田井中一貴、上田泰己、江幡正悟、宮園浩平.
    • Organizer
      第94回日本薬理学会年会(札幌、online)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βにより細胞周期が停止した口腔扁平上皮がん細胞は上皮間葉移行の誘導を介して運動能が亢進する2021

    • Author(s)
      齋藤万樹、高橋和樹、井上カタジナアンナ、榊谷振太郎、 小西徹、須河内昭成、戒田篤志、鯉沼代造、内橋俊大、三浦雅彦、宮園浩平、渡部徹郎
    • Organizer
      第44回日本分子生物学会年会(横浜)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βファミリーを標的としたがん治療戦略 (教育講演)2021

    • Author(s)
      宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] 淡明細胞型腎細胞癌におけるendoglin陽性細胞のがん幹細胞としての評価 (ワークショップ)2021

    • Author(s)
      桃井悠作、西田純、宮國昂介、江幡正悟、宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 組織透明化手法のがん研究への応用 (日本癌学会奨励賞受賞講演)2021

    • Author(s)
      髙橋恵生、宮園浩平
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-β signaling and its roles in progression of cancer (Oral; Introduction Course for Current Cancer Research)2021

    • Author(s)
      Miyazono K.
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] 三次元病理解析に資する組織透明化手法の開発(シンポジウム)2021

    • Author(s)
      久保田晋平、高橋恵生、田井中一貴、江幡正悟、上田泰己、宮園浩平
    • Organizer
      第110回日本病理学会総会(東京、online)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Molecular mechanism of neutrophil-dependent metastasis of inflammatory renal cancer (Symposium)2021

    • Author(s)
      Ehata S, Nishida J, Miyakuni K, Koinuma D, Miyazono K.
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice (Oral, Award for the Best Short Talk)2021

    • Author(s)
      Morikawa M, Ozawa T, Miyazono K.
    • Organizer
      FASEB Science Research Conference, The TGF-β Superfamily: Signaling in Development and Disease (online)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 組織透明化のがん研究への応用(シンポジウム)2021

    • Author(s)
      高橋恵生、宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-βシグナルとがん:最近の研究と今後の展望(特別講演)2021

    • Author(s)
      宮園浩平
    • Organizer
      第66回日本口腔外科学会総会・学術大会(幕張)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Identification of genes and their regulatory mechanisms related to the metastasis of triple-negative breast cancer (Oral)2021

    • Author(s)
      Ogikubo K, Tamura Y, Nishida J, Takahashi K, Morikawa M, Ehata S, Koinuma D, Miyazono K.
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Activation of epithelial-mesenchymal transition program in oral cancer cells under TGF-β-induced cell cycle arrest. on-line conference (優秀発表賞)2021

    • Author(s)
      Inoue KA, Takahashi K, Sakakitani S, Koinuma D, Sugauchi A, Saito M, Kaida A, Yoshimatsu Y, Uchihashi T, Miura M, Miyazono K, Watabe T.
    • Organizer
      FASEB Science Research Conference; The TGF-β Superfamily: Signaling in Development and Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] 組織透明化手法のがん研究への応用 (日本癌学会奨励賞受賞講演)2021

    • Author(s)
      髙橋恵生、宮園浩平
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β signaling and its roles in progression of cancer (Oral; Introduction Course for Current Cancer Research)2021

    • Author(s)
      Miyazono K.
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β により細胞周期が静止した口腔扁平上皮がん細胞は上皮間葉移行の誘導を介して運動・転移能が亢進する2021

    • Author(s)
      高橋和樹、井上カタジナアンナ、榊谷振太郎、小西徹、須河内昭成、齋藤万樹、戒田篤志 、鯉沼代造、吉松康裕、内橋俊大、古郷幹彦、三浦雅彦、宮園浩平、渡部徹郎
    • Organizer
      第80回日本癌学会学術総会(横浜、hybrid)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] トリプルネガティブ乳がんTNBCの高悪性化に伴うエピゲノム変化と治療標的遺伝子の同定 (口演:優秀演題賞)2021

    • Author(s)
      荻窪一貴、田村佑介、西田純、高橋恵生、江幡正悟、鯉沼代造、宮園浩平
    • Organizer
      第25回日本がん分子標的治療学会学術集会(online)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] A mechanism of therapeutic potency of polyI:C in the experimental model of triple negative cancer (Oral Session)2020

    • Author(s)
      Tamura Y, Koinuma D, Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] 腫瘍組織内ダイバーシティーの解析に資する全身全細胞解析技術の構築2020

    • Author(s)
      久保田晋平、高橋恵生、西田純、江幡正悟、田井中一貴、上田泰己、宮園浩平
    • Organizer
      新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第5回公開シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β signaling in progression of cancer (Core Symposia: Molecular carcinogenesis; Footprints and future)2020

    • Author(s)
      Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Chronic TGF-β exposure drives stabilized EMT, tumor stemness and drug resistance with vulnerability to mTOR inhibition (Oral Session)2020

    • Author(s)
      Katsuno Y, Miyazono K, Derynck R.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Analysis of tumor microenvironment with tissue-clearing technology (ワークショップ 微小環境・血管新生・低酸素)2020

    • Author(s)
      Takahashi K, Ehata S, Miyazono K.
    • Organizer
      第24回日本がん分子標的治療学会学術集会(徳島)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Identification of key molecules in pancreatic cancer metastasis using a mouse orthotopic inoculation model (ワークショップ 転移・浸潤)2020

    • Author(s)
      Miyauchi K, Takahashi K, Ehata S, Miyazono K.
    • Organizer
      第24回日本がん分子標的治療学会学術集会(徳島)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] DNAメチル化を介した腎がん細胞のアポトーシス耐性獲得の分子機構2020

    • Author(s)
      宮國昂介、西田純、江幡正悟、宮園浩平
    • Organizer
      新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第5回公開シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Chronic TGF-β exposure drives stabilized EMT, tumor stemness and drug resistance with vulnerability to mTOR inhibition(Oral Session)2020

    • Author(s)
      Katsuno Y, Miyazono K, Derynck R.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Analysis of tumor microenvironment with tissue-clearing technology (ワークショップ 微小環境・血管新生・低酸素)2020

    • Author(s)
      Takahashi K, Ehata S, Miyazono K.
    • Organizer
      第24回日本がん分子標的治療学会学術集会(徳島、online)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] Mitochondrial dysfunction in renal cancer progression(Oral Sessions)2020

    • Author(s)
      Ehata S, Miyakuni K, Nishida J, Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Mechanisms of neutrophi-dependent metastasis of inflammatory renal cell carcinoma (International Sessions: New therapeutic strategy for controlling metastasis and relapse in cancer)2020

    • Author(s)
      Miyazono K, Ehata S, Nishida J, Takahashi K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Effect of polyI:C on triple negative breast cancer cells (ポスター)2020

    • Author(s)
      Tamura Y, Koinuma D, Miyazono K.
    • Organizer
      第24回日本がん分子標的治療学会学術集会(徳島、online)
    • Data Source
      KAKENHI-PROJECT-20H00513
  • [Presentation] TGF-β signaling in progression of cancer(Core Symposia: Molecular carcinogenesis; Footprints and future)2020

    • Author(s)
      Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Whole-organ quantitative analysis of cancer metastasis with single cell resolution(Symposia: Single cell biology of cancer)2020

    • Author(s)
      Kubota S, Takahashi K, Nishida J, Ehata S, Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Comparative analysis of TTF-1 binding DNA regions in small-cell lung cancer and non-small-cell lung cancer cells(Oral Session)2020

    • Author(s)
      Hokari S, Tamura Y, Kaneda A, Katsura A, Morikawa M, Ehata S, Tsusumi S, Ishikawa Y, Aburatani H, Kikuchi T, Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Whole-organ quantitative analysis of cancer metastasis with single cell resolution(Symposia: Single cell biology of cancer)2020

    • Author(s)
      Kubota S, Takahashi K, Nishida J, Ehata S, Miyazono K.
    • Organizer
      第79回日本癌学会学術総会(広島)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Visualization of tumor microenvironment using tissue-clearing technology (English oral session)2019

    • Author(s)
      Takahashi K, Kubota SI, Ehata S, Miyazono K.
    • Organizer
      第78回日本癌学会総会 (京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Renal cancer cells acquire additional anti-apoptotic ability through the interactions with renal microenvironment2019

    • Author(s)
      Miyakuni K, Nishida J, Ehata S, Miyazono K.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Analyses of cancer metastasis regulated by tumor microenvironments using orthotopic transplantation models2019

    • Author(s)
      Miyazono K, Takahashi K, Kubota SI, Miyakuni K, Nishida J, Ehata S.
    • Organizer
      第78回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Tyrosine kinase Eph receptor A6 sensitizes glioma-initiating cells towards bone morphogenetic protein-induced apoptosis2019

    • Author(s)
      Morikawa M, Raja E, Miyazono K
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Palbociclib enhances activin-SMAD-induced cytostasis in estrogen receptor-positive breast cancer2019

    • Author(s)
      Ozawa T, Harada M, Morikawa M, Kobayashi M, Tamura Y, Takahashi K, Tanabe M, Tada K, Seto Y, Miyazono K, Koinuma D
    • Organizer
      11th AACR-JCA joint conference (Hawaii, USA)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Targeting metastasis-associated inflammation in renal cancer by BET inhibitor2019

    • Author(s)
      Nishida J, Tamura Y, Takahashi K, Koinuma D, Ehata S, Miyazono K.
    • Organizer
      第78回日本癌学会学術総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β family signaling in progression of cancer (The Nakahara Memorial Lecture Prize)2019

    • Author(s)
      Miyazono K, Tanabe R
    • Organizer
      The 50th Commemorative International Symposium of the Princess Takamatsu Cancer Research Fund: New Horizons for Cancer Research and Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Application of tissue clearing technology in cancer research2019

    • Author(s)
      Takahashi K, Miyazono K
    • Organizer
      Elventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] BMP-induced homeobox transcription factor regulates differentiation of glioma-initiating cells2019

    • Author(s)
      田邉 諒,宮園 浩平
    • Organizer
      第19回東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Tyrosine kinase receptor EphA6 sensitizes glioblastoma cells towards BMP-induced apoptosis2019

    • Author(s)
      Raja E, Morikawa M, Tanabe R, Ino Y, Saito N, Todo T, Miyazono K.
    • Organizer
      Elventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Roles of tumor microenvironment in pancreatic and renal cancer progression using orthotopic transplantation models2019

    • Author(s)
      Miyazono K.
    • Organizer
      2019 TGF-β Signaling Meeting in Leiden
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Targeting transcriptional dysregulation of TGF-β-Smad signaling for cancer therapy (Symposium)2019

    • Author(s)
      Koinuma D, Isogaya K, Harada M, Tsutsumi S, Katsura A, Murai F, Tamura Y, Morikawa M, Nakaki R, Mizutani A, Ehata S, Aburatani H, Miyazono K.
    • Organizer
      第78回日本癌学会総会 (京都)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β family signaling in progression of cancer (The Nakahara Memorial Lecture Prize)2019

    • Author(s)
      Miyazono K, Tanabe R
    • Organizer
      The 50th Commemorative International Symposium of the Princess Takamatsu Cancer Research Fund: New Horizons for Cancer Research and Precision Medicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-beta Family Signaling in Cardiovascular Diseases2019

    • Author(s)
      宮園浩平
    • Organizer
      第83回日本循環器学会学術集会(真下記念講演;横浜)
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] 微小環境との相互作用を介した腎がん細胞のアポトーシス耐性獲得2019

    • Author(s)
      宮國昂介、西田純、江幡正悟、宮園浩平
    • Organizer
      新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第4回公開シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] BET阻害剤の炎症を標的とした腎がん転移抑制効果2019

    • Author(s)
      西田純、桃井悠作、田村佑介、高橋恵生、鯉沼代造、江幡正悟、宮園浩平
    • Organizer
      新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第4回公開シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] BMP signaling in glioblastoma2019

    • Author(s)
      Miyazono K, Tanabe R
    • Organizer
      2019 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Analysis of molecular mechanism of renal cancer progression using serial orthotopic transplantation model2019

    • Author(s)
      Miyakuni K, Nishida J, Ehata S, Miyazono K.
    • Organizer
      Elventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 腎細胞がんのエンハンサーリモデリングは好中球を介した肺転移機構を誘導する2019

    • Author(s)
      西田純、高橋恵生、江幡正悟、宮園浩平
    • Organizer
      第28回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 膵微小環境によるがん細胞の悪性形質の獲得機構2019

    • Author(s)
      高橋恵生、江幡正悟、宮園浩平
    • Organizer
      第28回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] マウス移植モデルを用いた膵がん新規標的分子の探索2019

    • Author(s)
      高橋恵生、江幡正悟、宮園浩平
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-βシグナル研究を通じた細胞ダイバーシティーの解明(基調講演)2019

    • Author(s)
      宮園浩平
    • Organizer
      新学術領域「細胞社会ダイバーシティーの統合的解明と制御」第2回若手ワークショップ
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 腎細胞がんの好中球を介した肺転移機構に対するBET阻害剤の効果の検討2019

    • Author(s)
      西田純、高橋恵生、江幡正悟、宮園浩平
    • Organizer
      第23回日本がん分子標的治療学会学術集会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β family signaling in invasion and metastasis of cancer (Keynote speech)2019

    • Author(s)
      Miyazono K.
    • Organizer
      112th Annual Meeting of the Formosan Medical Association (Taipei, Taiwan)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β Family Signaling in Cardiovascular Diseases(真下記念講演)2019

    • Author(s)
      宮園浩平
    • Organizer
      第83回日本循環器学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Regulation of the Development of Lung Cancer by TGF-β Signaling2018

    • Author(s)
      Miyazono K
    • Organizer
      The 6th JCA-AACR Special Joint Conference (Kyoto)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-βファミリーのシグナル伝達とがんの浸潤・転移に関する研究(吉田富三賞受賞講演)2018

    • Author(s)
      宮園浩平
    • Organizer
      第77回日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 組織透明化技術のがん研究への応用(シンポジウム)2018

    • Author(s)
      高橋恵生、宮園浩平
    • Organizer
      第22回日本がん分子標的治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 好中球依存的な腎細胞がん細胞肺転移機構を説明するエピゲノムの探索2018

    • Author(s)
      西田純、高橋恵生、江幡正悟、宮園浩平
    • Organizer
      第27回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] ロングノンコーディングRNA NORADによるTGF-βシグナルおよび上皮間葉転換様形質の制御2018

    • Author(s)
      鯉沼代造、川崎夏実、穂苅諭、宮園浩平
    • Organizer
      第77回日本癌学会学術総会(大阪)
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] がん研究の進歩:基礎研究からゲノム医療まで2018

    • Author(s)
      宮園浩平
    • Organizer
      第118回日本外科学会定期学術集会(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Mechanisms of action of BMPs in human malignant glioma2018

    • Author(s)
      Miyazono K.
    • Organizer
      12th International BMP conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] がん研究の進歩:基礎研究からゲノム医療まで2018

    • Author(s)
      宮園浩平
    • Organizer
      第118回日本外科学会定期学術集会
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β ファミリーによる細胞分化とダイバーシティー獲得の分子基盤2018

    • Author(s)
      宮園浩平
    • Organizer
      新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第1回公開シンポジウム(大阪)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Epigenetic remodeling of renal cancer cells in primary tumor microenvironment triggers neutrophil-dependent lung metastasis2018

    • Author(s)
      Nishida J, Tamura Y, Takahashi K, Koinuma D, Ehata S, Miyazono K.
    • Organizer
      第18回東京大学生命科学シンポジウム
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-βファミリーのシグナル伝達とがんの浸潤・転移に関する研究2018

    • Author(s)
      宮園浩平
    • Organizer
      第77回日本癌学会学術総会(吉田富三賞受賞講演;大阪)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] 長期TGF-β刺激はmTOR依存的に乳がん細胞のEMTと幹細胞様形質を安定化させる2018

    • Author(s)
      勝野蓉子、宮園浩平、Derynck R
    • Organizer
      第77回日本癌学会学術総会(大阪)
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β ファミリーによるがん幹細胞分化とがん転移の制御機構2017

    • Author(s)
      宮園浩平
    • Organizer
      第63回日本病理学会秋期特別総会(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] BMP signaling suppresses stemness properties of glioblastoma cells2017

    • Author(s)
      Tanabe R, Miyazono K
    • Organizer
      TGFβ meeting in Uppsala 2017 (Uppsala, Sweden)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Invasion and metastasis of cancer: Analysis of the roles of EMT using experimental animal models2017

    • Author(s)
      Miyazono K
    • Organizer
      第76回日本癌学会学術総会(横浜)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β ファミリーによるがん幹細胞分化とがん転移の制御機構2017

    • Author(s)
      宮園浩平
    • Organizer
      第63回日本病理学会秋期特別総会(東京)
    • Invited
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Invasion and metastasis of cancer: Analysis of the roles of EMT using experimental animal models2017

    • Author(s)
      Miyazono K
    • Organizer
      第76回日本癌学会学術総会(横浜)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] ZEB1-regulated inflammatory phenotype in breast cancer cells2017

    • Author(s)
      Katsura A, Tamura Y, Morikawa M, Sakurai T, Takahashi K, Mizutani A, Nishida J, Yokoyama Y, Morishita Y, Murakami T, Ehata S, Miyazono K, Koinuma D.
    • Organizer
      FASEB Science Research Conference "TGF-β Superfamily: Signaling in Development and Disease" (Lisbon, Portugal)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β signaling in cancer2017

    • Author(s)
      Miyazono K
    • Organizer
      The 48th International Symposium of the Princess Takamatsu Cancer Research Fund“Complexity in Cancer-host Crosstalk” (Tokyo)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β Family Signaling in Regulation of Cancer2017

    • Author(s)
      Miyazono K
    • Organizer
      International Symposium on TGF-β Biology: Cell Signaling, Development and Human Diseases:中国細胞生物学学会2017年全国学術大会 (Xiamen, China)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β signaling in cancer2017

    • Author(s)
      Miyazono K
    • Organizer
      The 48th International Symposium of the Princess Takamatsu Cancer Research Fund“Complexity in Cancer-host Crosstalk” (Tokyo)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] 網羅的な転写因子結合部位の解析が明らかにするTGF-βシグナル下流の遺伝子発現制御機構(ワークショップ)2017

    • Author(s)
      鯉沼 代造、堤 修一、磯谷 一暢、森川 真大、Eleftheria Vasilaki、水谷 アンナ、荒瀬 麻友、桂 彰宏、川崎 夏実、田村 佑介、油谷 浩幸、宮園 浩平
    • Organizer
      2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会、第90回日本生化学会大会)(神戸)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Cancer research in Japan: Past, present, and future (Keynote Session)2017

    • Author(s)
      Miyazono K
    • Organizer
      National Taiwan University Cancer Center YongLin Chair Forum: The 2nd Meeting of Taiwan YongLin Healthcare Symposium Series on “Immunotherapy and Precision Medicine” (Taipei, Taiwan)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Whole-body/organ profiling of cancer metastasis with CUBIC-Cancer analysis2017

    • Author(s)
      Shimpei I Kubota, Kei Takahashi, Jun Nishida, Shogo Ehata, Kazuki Tainaka, Ueda R. Hiroki, Kohei Miyazono
    • Organizer
      2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会、第90回日本生化学会大会)(神戸)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] がん微小環境との相互作用により悪性化した腎細胞がん細胞は好中球の動態変化を誘発して肺転移を促進する2017

    • Author(s)
      西田 純、高橋 恵生、江幡 正悟、宮園 浩平
    • Organizer
      2017年度生命科学系学会合同年次大会(第40回日本分子生物学会年会、第90回日本生化学会大会)(神戸)
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] Cancer research in Japan: Past, present, and future (Keynote Session)2017

    • Author(s)
      Miyazono K
    • Organizer
      National Taiwan University Cancer Center YongLin Chair Forum: The 2nd Meeting of Taiwan YongLin Healthcare Symposium series on “Immunotherapy and Precision Medicine” (Taipei, Taiwan)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] BMP signaling in glioma-initiating cells2017

    • Author(s)
      Miyazono K
    • Organizer
      FASEB Science Research Conference "TGF-β Superfamily: Signaling in Development and Disease" (Lisbon, Portugal)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β Family Signaling in Regulation of Cancer2017

    • Author(s)
      Miyazono K
    • Organizer
      International Symposium on TGF-β Biology: Cell Signaling, Development and Human Diseases:中国細胞生物学学会2017年全国学術大会 (Xiamen, China)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-17H06326
  • [Presentation] TGF-β signaling: Mechanisms of action and clinical application2016

    • Author(s)
      Miyazono K
    • Organizer
      第22回日本遺伝子細胞治療学会
    • Place of Presentation
      虎ノ門ヒルズ・東京都
    • Year and Date
      2016-07-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] 長期TGF-β刺激はAktシグナル活性化を介して乳がん細胞の幹細胞様形質を安定化させる2016

    • Author(s)
      勝野蓉子、宮園浩平、Derynck R
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜・横浜市
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β family signaling in angiogenesis and lymphangiogenesis2016

    • Author(s)
      Miyazono K
    • Organizer
      The 24th Annual Meeting of the Japanese Vascular Biology and Medicine Organization/The 14th Korea-Japan Joint Symposium on Vascular Biology
    • Place of Presentation
      Nagasaki Brick Hall・長崎市
    • Year and Date
      2016-12-08
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Autocrine BMP-4 is a novel therapeutic target for colorectal cancer2016

    • Author(s)
      Yokoyama Y, Ehata S, Morishita Y, Watanabe T, Miyazono K.
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Decreased expression of TGFBR3 promotes progression of renal cell carcinomas through a multi-step mechanism2016

    • Author(s)
      Nishida J, Ehata S, Miyazono K.
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β研究の過去・現在・未来2016

    • Author(s)
      宮園浩平
    • Organizer
      第46回日本創傷治癒学会
    • Place of Presentation
      東京大学安田講堂・東京都
    • Year and Date
      2016-12-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] BMP signaling in glioma-initiating cells2016

    • Author(s)
      Miyazono K
    • Organizer
      11th International BMP Conference
    • Place of Presentation
      Harvard Medical School, Boston, MA, USA
    • Year and Date
      2016-10-28
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Prolonged exposure to TGF-β stabilizes stem-cell state of breast cancer cells through activation of Akt signaling2016

    • Author(s)
      Katsuno Y, Miyazono K, Derynck R.
    • Organizer
      Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
    • Place of Presentation
      Maui, Hawaii, U.S.A.
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-βファミリーと血管・リンパ管新生2016

    • Author(s)
      宮園浩平
    • Organizer
      第40回日本リンパ学会総会
    • Place of Presentation
      伊藤国際学術研究センター・東京都
    • Year and Date
      2016-06-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TUFT1は核周囲へのlysosome集積を促進しmTORC1活性化を促進する2016

    • Author(s)
      川崎夏実、旦慎吾、矢守隆夫、江幡正悟、宮園浩平、鯉沼代造
    • Organizer
      第20回日本がん分子標的治療学会学術集会
    • Place of Presentation
      別府国際コンベンションセンター・別府市
    • Year and Date
      2016-05-30
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-βファミリーからみた内科学2016

    • Author(s)
      宮園浩平
    • Organizer
      第113回日本内科学会講演会
    • Place of Presentation
      東京国際フォーラム・東京都
    • Year and Date
      2016-04-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-βファミリーとがん:その多彩な作用と臨床応用2016

    • Author(s)
      宮園浩平
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜・横浜市
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-betaファミリーシグナルとがん(モーニングセミナー)2015

    • Author(s)
      宮園浩平
    • Organizer
      第16回運動器科学研究会
    • Place of Presentation
      南日本新聞みなみホール(鹿児島県・鹿児島市)
    • Year and Date
      2015-09-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] Paired related homeobox 1 inhibits the tumorigenic ability of glioma-initiating cells2015

    • Author(s)
      Tanabe R, Iwata C, Miyazono K.
    • Organizer
      TGF-beta meeting in Uppsala
    • Place of Presentation
      Uppsala University (Uppsala, Sweden)
    • Year and Date
      2015-08-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] TGF-β2-TGBR3シグナルは淡明細胞型腎細胞癌の癌幹細胞制御に重要な因子である2015

    • Author(s)
      西田 純、江幡正悟、宮園浩平
    • Organizer
      第38回日本分子生物学会年会・第88回日本生化学会 大会合同大会
    • Place of Presentation
      名古屋国際会議場・名古屋
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Regulation of the progression of lung cancer by TGF-β2015

    • Author(s)
      Miyazono K, Koinuma D, Ehata S.
    • Organizer
      FASEB Science Research Conference "The TGF-β Superfamily: Signaling in Development and Disease"
    • Place of Presentation
      Snowmass, CO, U.S.A.
    • Year and Date
      2015-07-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] TGF-β ファミリーのがん微小環境に及ぼす作用とがん治療戦略(シンポジウム)2015

    • Author(s)
      宮園浩平
    • Organizer
      平成26年度 文部科学省 新学術領域研究「がん研究分野の特性等を踏まえた支援活動」公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都・千代田区)
    • Year and Date
      2015-01-27
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] The Arkadia-ESRP2 axis suppresses tumor progression: Analyses in clear cell renal cell carcinoma2015

    • Author(s)
      Mizutani A, Koinuma D, Seimiya H, Miyazono K
    • Organizer
      AACR Annual Meeting 2015
    • Place of Presentation
      Pennsylvania Convention Center (Philadelphia, PA, USA)
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Role of TGFBR3 in the regulation of renal cancer-initiating cells2015

    • Author(s)
      Nishida J, Ehata S, Miyazono K.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場・名古屋
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] 脳腫瘍幹細胞を治療標的としたBMPによる分化誘導メカニズムの解析(ワークショップ)2015

    • Author(s)
      田邉 諒、岩田 要、宮園浩平
    • Organizer
      日本がん分子標的治療学会第19回学術集会
    • Place of Presentation
      松山全日空ホテル(愛媛県・松山市)
    • Year and Date
      2015-06-10
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] Regulation of cancer invasion and metastasis by TGF-β signalling2015

    • Author(s)
      Miyazono K.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場・名古屋
    • Year and Date
      2015-10-08
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05774
  • [Presentation] Regulation of the progression of lung cancer by TGF-beta2015

    • Author(s)
      Miyazono K.
    • Organizer
      FASEB Scientific Research Conference: The TGF-Beta Superfamily: Signaling in Development and Disease
    • Place of Presentation
      Base Village Conference Center (Snowmass, CO, USA)
    • Year and Date
      2015-07-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Analyses of the mechanisms underlying BMP-induced differentiation of glioma-initiating cells2015

    • Author(s)
      Tanabe R, Komuro A, Ino Y, Todo T, Iwata C, Miyazono K.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] Analysis of pancreatic microenvironment with an orthotopic injection model and in vivo bioluminescence imagine system2015

    • Author(s)
      Ehata S, Takahashi K, Koinuma D, Miyazono K.
    • Organizer
      日本癌学会シンポジウム/共同利用・共同研究拠点シンポジウム : がん幹細胞・微小環境・分子標的~がん進展制御への挑戦
    • Place of Presentation
      石川県立音楽堂交流ホール(石川県・金沢市)
    • Year and Date
      2015-01-21
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] がんの浸潤と転移の分子機構(若手研究者教育レクチャー)2015

    • Author(s)
      宮園浩平
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県・名古屋市)
    • Year and Date
      2015-04-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] 肺線癌におけるTGF-β標的遺伝子RBM47の発現と作用機構の解析2014

    • Author(s)
      櫻井 翼、鯉沼代造、磯谷一暢、坂井 慧、森川真大、森下保幸、江幡正悟、宮園浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 小細胞肺がんにおける TGF-β シグナルの機能解析2014

    • Author(s)
      村井文彦、江幡正悟、鯉沼代造、牛久 綾、深山正久、宮園浩平
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 腎癌幹細胞における TGF-β の機能解析2014

    • Author(s)
      西田 純、江幡正悟、宮園浩平
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 肺線癌におけるTGF-β標的遺伝子RBM47の発現と作用機構の解析2014

    • Author(s)
      櫻井 翼、鯉沼代造、江幡正悟、宮園浩平
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県・仙台市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Surface expression of podoplanin/aggrus on haptokinetic scaffolds positively regulates adhesive migration of T lymphocytes2014

    • Author(s)
      Iwata C, Miyazono K
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      みやこめっせ京都(京都府・京都市)
    • Year and Date
      2014-04-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 大腸癌細胞はBMP-4を自己分泌し、アポトーシスを抑制する2014

    • Author(s)
      横山雄一郎、江幡正悟、宮園浩平
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県・仙台市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] がん治療法の未来 - TGF-βファミリーシグナル分子を中心に(基調講演)2014

    • Author(s)
      宮園浩平
    • Organizer
      第52回日本癌治療学会学術集会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-08-28
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 小細胞肺がんにおけるTGF-βシグナルの機能解析(ワークショップ)2014

    • Author(s)
      村井文彦、江幡正悟、宮園浩平
    • Organizer
      第18回日本がん分子標的治療学会学術集会
    • Place of Presentation
      仙台市情報・産業プラザ(宮城県・仙台市)
    • Year and Date
      2014-06-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] BMP-9/ALK-1 signals negatively regulate the formation of lymphatic vessels in development and cancer progression by downregulating Prox1 expression2014

    • Author(s)
      Yoshimatsu Y, Lee YG, Akatsu Y, Taguchi L, Suzuki HI, Cunha SI, Suzuki Y, Yamazaki T, Katsura A, Morishita Y, Oh SP, Zimmers TA, Lee SJ, Pietras K, Koh GY, Watabe T, Miyazono K.
    • Organizer
      The 18th International Vascular Biology Meeting
    • Place of Presentation
      みやこめっせ京都(京都府・京都市)
    • Year and Date
      2014-04-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Regulation of EMT and related phenotypes by TGF-β in cancer cells (Symposium)2014

    • Author(s)
      Koinuma D, Isogaya K, Sakurai T, Kawasaki N, Ehata S, Tsutsumi S, Saito A, Miyazawa K, Aburatani H, Miyazono K.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Emerging regulatory mechanism of mTOR signaling by a novel TGF-β target gene (English Oral Session)2014

    • Author(s)
      Kawasaki N, Isogaya K, Koinuma D, Ehata S, Miyazono K.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 大腸癌におけるBMP-4の機能解析2014

    • Author(s)
      江幡正悟、横山雄一郎、宮園浩平
    • Organizer
      第21回BMP研究会
    • Place of Presentation
      大阪大学中之島センター(大阪府・大阪市)
    • Year and Date
      2014-07-27
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] microRNAの細胞外分泌と細胞間コミュニケーションにおけるTGF-βシグナルの役割2014

    • Author(s)
      桂 彰宏、鈴木 洋、杉本耕一、宮園浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 肺腺癌細胞におけるFoxA1/2のSmad3標的遺伝子の制御2014

    • Author(s)
      磯谷一暢、鯉沼代造、堤 修一、油谷浩幸、宮園浩平
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      国立京都国際会館(京都府・京都市)
    • Year and Date
      2014-10-15
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Autocrine BMP-4 protects colorectal cancer cells from apoptosis through down-regulation of Bim (English Oral Session)2014

    • Author(s)
      Yokoyama Y, Ehata S, Miyazono K.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県・横浜市)
    • Year and Date
      2014-09-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 小細胞肺癌の進展におけるTGF-βの機能解析2014

    • Author(s)
      江幡正悟、村井文彦、宮園浩平
    • Organizer
      第103回日本病理学会総会
    • Place of Presentation
      広島国際会議場(広島県・広島市)
    • Year and Date
      2014-04-24
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-beta signals in tumor microenvironment and treatment of cancer2013

    • Author(s)
      Kohei Miyazono
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] リンパ管形成におけるBMP-9/ALK-1シグナルの役割2013

    • Author(s)
      吉松康裕、赤津裕一、田口瑠奈、鈴木 洋、渡部徹郎、宮園浩平
    • Organizer
      第20回BMP研究会
    • Place of Presentation
      アクトシティ浜松コングレスセンター(静岡県浜松市)
    • Year and Date
      2013-07-05
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Keynote Presentation: EMT and EndMT induced by TGF-beta2013

    • Author(s)
      Kohei Miyazono
    • Organizer
      UCSF Symposium: Transforming Growth Factor Signaling
    • Place of Presentation
      UCSF (San Francisco, U.S.A.)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] TGF-beta signaling in regulation of cancer stem cells and EMT2013

    • Author(s)
      Kohei Miyazono
    • Organizer
      FASEB Scientific Research Conference: TGF-beta Superfamily: Signaling in Development and Disease
    • Place of Presentation
      Steamboat Springs (Colorado, U.S.A.)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] Keynote Presentation: EMT and EndMT induced by TGF-beta2013

    • Author(s)
      Kohei Miyazono
    • Organizer
      UCSF Symposium: Transforming Growth Factor Signaling
    • Place of Presentation
      UCSF (San Francisco, U.S.A.)
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] 腫瘍微小循環の機能的破綻2012

    • Author(s)
      宮園浩平
    • Organizer
      千里ライフサイエンスセミナー「がんの転移・浸潤と微小環境」
    • Place of Presentation
      千里ライフサイエンスセンタービル(大阪府豊中市)(招待講演)
    • Year and Date
      2012-02-24
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] 腫瘍微小循環の機能的破綻2012

    • Author(s)
      宮園 浩平
    • Organizer
      千里ライフサイエンスセミナー「がんの転移・浸潤と微小環境」
    • Place of Presentation
      千里ライフサイエンスセンタービル(大阪府豊中市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] BMPs and Regulation of Cancer (Charles Huggins Lecture)2012

    • Author(s)
      Kohei Miyazono
    • Organizer
      International conference on Bone moiphogenetic proteins
    • Place of Presentation
      Granlibakken Conference Center (Lake Tahoe, CA, USA)(招待講演)
    • Year and Date
      2012-07-21
    • Data Source
      KAKENHI-PROJECT-24390070
  • [Presentation] Tumor promotive and suppressive function of TGF-beta2012

    • Author(s)
      Kohei Miyazono
    • Organizer
      43rd International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      ホテルグランドパレス(東京)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Regulation of cancer initiating cell function by TGF-beta2012

    • Author(s)
      Kohei Miyazono
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Tumor promotive and suppressive function of TGF-beta2012

    • Author(s)
      Kohei Miyazono
    • Organizer
      The 43rd International Symposium of the Princess Takamatsu Cancer Research Fund
    • Place of Presentation
      ホテルグランドパレス(東京)
    • Year and Date
      2012-11-14
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] TGF-β signaling and tumor microenvironment2011

    • Author(s)
      Kohei Miyazono
    • Organizer
      JSIR-MMCB2011 (Japanese Society of Interferon & Cytokine Research/International Symposium on Molecular Cell Biology of Macrophage)
    • Place of Presentation
      ANAゲートタワーホテル大阪(大阪府泉佐野市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βシグナルによるがん微小環境ネットワークの制御2011

    • Author(s)
      宮園 浩平
    • Organizer
      第70回日本癌学会学術集会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-beta, EMT, and TGF-beta signaling inhibitors in cancer progression2011

    • Author(s)
      Kohei Miyazono
    • Organizer
      Keystone symposia : Epithelial plasticity and epithelial to mesenchymal transition
    • Place of Presentation
      Fairmont Waterfront(カナダ、バンクーバー)(招待講演)
    • Year and Date
      2011-01-25
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-beta, EMT, and TGF-beta signaling inhibitors in cancer progression2011

    • Author(s)
      Kohei Miyazono
    • Organizer
      Keystone symposia : Epithelial plasticity and epithelial to mesenchymal transition
    • Place of Presentation
      Fairmont Waterfront(カナダ、バンクーバー)
    • Year and Date
      2011-01-25
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] TGF-b signaling in tumor microenvironment2010

    • Author(s)
      Miyazono, K.
    • Organizer
      8th Conference of AACR and JCA : Cancer Genomics, Epigenomics, and the Develop.of Novel Therapeutics
    • Place of Presentation
      Hilton Waikoloa Village, Hawaii, USA
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] がん細胞とこれを取り巻く細胞・新しいがん治療の試み(市民公開講座)2010

    • Author(s)
      宮園浩平
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会・合同年会
    • Place of Presentation
      東京大学安田講堂(東京都文京区)
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] TGF-βシグナルのがん幹細胞と微小環境における役割2010

    • Author(s)
      宮園浩平
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)(日本癌学会-アメリカ癌学会合同シンポジウム)(招待講演)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Ets family members induce lymphangiogenesis via physical and functional interaction with Prox12010

    • Author(s)
      吉松康裕、三平元、宮園浩平、渡部徹郎, 他
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      梅田スカイビル(大阪府大阪市)
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] 神経膠腫幹細胞と神経前駆細胞における転写ネットワークの差異2010

    • Author(s)
      生島弘彬、宮園浩平, 他
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βシグナルのがん幹細胞と微小環境における役割(日本癌学会-アメリカ癌学会合同シンポジウム)2010

    • Author(s)
      宮園浩平
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際コンベンションセンター(大阪府大阪市)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] がん細胞とこれを取り巻く細胞・新しいがん治療の試み2010

    • Author(s)
      宮園浩平
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会・合同年会
    • Place of Presentation
      東京大学安田講堂(東京都文京区)(市民公開講座)(招待講演)
    • Year and Date
      2010-12-11
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Analysis of VEGFR2 signaling for endothelial differentiation of embryonic stem cell-derived VEGFR2+cells2010

    • Author(s)
      佐瀬仁志、渡部徹郎、宮園浩平, 他
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      梅田スカイビル(大阪府大阪市)
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Roles of TGF-beta signaling in cancer2010

    • Author(s)
      Kohei Miyazono
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会・合同年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)(大会長企画シンポジウム)(招待講演)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Roles of TGF-beta signaling in cancer(大会長企画シンポジウム)2010

    • Author(s)
      Kohei Miyazono
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会・合同年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] Identification of novel COUP-TFII isoform in blood vascular and lymphatic endothelial cells2010

    • Author(s)
      山崎智子、渡部徹郎、宮園浩平, 他
    • Organizer
      第18回日本血管生物医学会学術集会
    • Place of Presentation
      梅田スカイビル(大阪府大阪市)
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] Use of TGF-beta inhibitors for treatment of cancer2009

    • Author(s)
      Miyazono, K.
    • Organizer
      第68回日本癌学会学術総会
    • Place of Presentation
      横浜パシフィコ・横浜
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-β signaling in regulation of cancer-initiating cells and EMT2009

    • Author(s)
      Miyazono, K., et al.
    • Organizer
      FASEB Summer Res.Conf.- TGF-β superfamily ; Signaling in Development and Disease
    • Place of Presentation
      Carefree Resort, Arizona, USA
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] Optimal manipulation of tumor microvasculature for treatment of tumors using nanoparticles2009

    • Author(s)
      Miyazono, K.
    • Organizer
      TGF-β meeting in Uppsala
    • Place of Presentation
      University of Uppsala, Uppsala, Sweden
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] Regulation of cancer stem cell differentiation by TGF-β signaling2009

    • Author(s)
      Miyazono, K.
    • Organizer
      Japanese-German Cancer Workshop
    • Place of Presentation
      Baurs Park, Hamburg, Germany
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] New horizon of cancer research : from basic to translational research2008

    • Author(s)
      Miyazono K
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市(名古屋国際会議場)
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] Regulation of angiogenesis and lymphangiogenesis by TGF-β signaling2008

    • Author(s)
      Miyazono, K.
    • Organizer
      The U.S.-Japan Cooperative Cancer Research Program Workshop
    • Place of Presentation
      京都
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-19659098
  • [Presentation] Regulation of angiogenesis and lymphangiogenesis by TGF-β signaling2008

    • Author(s)
      Miyazono, K., et. al.
    • Organizer
      The U.S. Japan Cooperative Cancer Research Program Workshop
    • Place of Presentation
      京都
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] Clinical Application of Nanoparticles on Cancer Therapy2008

    • Author(s)
      Miyazono K
    • Organizer
      Micro- and Nano-Technologies in Medicine : A Swedish-Japanese Collaborative Workshop
    • Place of Presentation
      Uppsala, Sweden(ウプサラ大学)
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-β signaling and cancer2008

    • Author(s)
      Miyazono K
    • Organizer
      EMBO meeting on Cellular Signaling & Molecular Medicine 2008
    • Place of Presentation
      Cavtat/Dubrovnik, Croatia (Hotel Croatia)
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] Bidirectional roles of TGF-β signaling in cancer2008

    • Author(s)
      Miyazono, K.
    • Organizer
      The 28th Sapporo Cancer Seminar International Symposium"TGF-βsignaling and cancer"
    • Place of Presentation
      札幌・北海道大学学術交流会館
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-20659059
  • [Presentation] Regulation of angiogenesis and lymphangiogenesis by TGF-βsignaling2008

    • Author(s)
      Miyazono, K.
    • Organizer
      The U.S.-Japan Cooperative Cancer Research Program Workshop
    • Place of Presentation
      京都
    • Year and Date
      2008-03-19
    • Data Source
      KAKENHI-PROJECT-19209009
  • [Presentation] TGF-β signaling and Cancer2008

    • Author(s)
      Miyazono K
    • Organizer
      Uppsala University, Rudbeck seminar
    • Place of Presentation
      Uppsala, Sweden(ウプサラ大学)
    • Year and Date
      2008-10-23
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-β Signaling and Cancer2008

    • Author(s)
      Miyazono K
    • Organizer
      Anita Roberts Symposium : TGF-β : Discovery and Promise
    • Place of Presentation
      Bethesda, USA (NIH ; National Institute of Health)
    • Year and Date
      2008-09-19
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-β signaling in fibrosis, angiogenesis, and lymphangiogenesis2007

    • Author(s)
      Miyazono, K., et. al.
    • Organizer
      FASEB Summer Research Conference: TGF-β Superfamily: Signaling & Development
    • Place of Presentation
      Arizona, USA
    • Year and Date
      2007-07-18
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-βシグナルによるがんの進展とその制御2007

    • Author(s)
      宮園 浩平
    • Organizer
      第27回日本医学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-04-06
    • Data Source
      KAKENHI-PROJECT-17016011
  • [Presentation] TGF-β ファミリーシグナルの分子機構

    • Author(s)
      宮園浩平
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2013-12-03 – 2013-12-06
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] BMP-9/ALK1 signals negatively regulate the lymphatic vessel formation in development and cancer by downregulating Prox1

    • Author(s)
      吉松康裕、Lee YG、赤津裕一、田口瑠奈、鈴木 洋、Cunha SI、鈴木夕佳、山崎智子、桂 彰宏、森下保幸、Oh SP、Zimmers TA、Lee SJ、Pietras K、Koh GY、渡部徹郎、宮園浩平
    • Organizer
      第21回日本血管生物医学会学術集会
    • Place of Presentation
      千里阪急ホテル(大阪府豊中市)
    • Year and Date
      2013-09-26 – 2013-09-28
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βは小細胞肺がんの進展を抑制する

    • Author(s)
      村井文彦、江幡正悟、宮園浩平
    • Organizer
      第17回日本がん分子標的治療学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2013-06-12 – 2013-06-14
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] EMT and EndMT induced by TGF-β (Keynote Presentation)

    • Author(s)
      Miyazono K.
    • Organizer
      Transforming Growth Factor Signaling : Anniversary Symposium
    • Place of Presentation
      UCSF (San Francisco, U.S.A.)
    • Year and Date
      2013-04-05 – 2013-04-06
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βシグナルによるがん幹細胞・微小環境の制御

    • Author(s)
      宮園浩平
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      ロイトン札幌(北海道札幌市)
    • Year and Date
      2013-06-06 – 2013-06-08
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] リンパ管発生および腫瘍リンパ管新生におけるBMP-9/ALK-1シグナルの役割

    • Author(s)
      吉松康裕、Lee YG、赤津裕一、田口瑠奈、鈴木 洋、Cunha SI、丸山和一、鈴木夕佳、山崎智子、桂 彰宏、森下保幸、Oh SP、Zimmers TA、Lee SJ、Pietras K、Koh GY、渡部徹郎、宮園浩平
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜パシフィコ(神奈川県横浜市)
    • Year and Date
      2013-09-11 – 2013-09-13
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βによるがん進展制御

    • Author(s)
      宮園浩平
    • Organizer
      第22回日本がん転移学会学術集会・総会
    • Place of Presentation
      ホテルブエナビスタ(長野県松本市)
    • Year and Date
      2013-07-11 – 2013-07-12
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-β signaling in regulation of cancer stem cells and EMT

    • Author(s)
      Miyazono K.
    • Organizer
      FASEB Summer Research Conferences on the TGF-β Superfamily
    • Place of Presentation
      Steamboat Spring (Colorado, U.S.A.)
    • Year and Date
      2013-07-28 – 2013-08-02
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-beta signals in tumor microenvironment and treatment of cancer

    • Author(s)
      Miyazono K.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜パシフィコ(神奈川県横浜市)
    • Year and Date
      2013-10-03 – 2013-10-05
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βシグナルとがん

    • Author(s)
      宮園浩平
    • Organizer
      平成25年度 がん若手研究者ワークショップ
    • Place of Presentation
      蓼科グランドホテル(長野県茅野市)
    • Year and Date
      2013-09-04 – 2013-09-07
    • Invited
    • Data Source
      KAKENHI-PLANNED-22112002
  • [Presentation] TGF-βファミリーのがん微小環境に及ぼす作用とがん治療戦略

    • Author(s)
      宮園 浩平
    • Organizer
      がん研究分野の特性等を踏まえた支援活動・公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Year and Date
      2015-01-27 – 2015-01-28
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • [Presentation] リンパ管形成におけるTGF-βファミリーシグナルの役割

    • Author(s)
      吉松康裕、Yulia G Lee、赤津裕一、田口瑠奈、鈴木洋、Sara I Cunha、鈴木夕佳、山崎智子、桂彰宏、森下保幸、S Paul Oh、Teresa A Zimmers、Se-Jin Lee、Kristian Pietras、Gou Young Koh、渡部徹郎、宮園浩平
    • Organizer
      がん研究分野の特性等を踏まえた支援活動・公開シンポジウム
    • Place of Presentation
      学術総合センター(東京都千代田区)
    • Year and Date
      2015-01-27 – 2015-01-28
    • Data Source
      KAKENHI-ORGANIZER-22112001
  • []

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  • 1.  KAWABATA Masahiro (60224838)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 2.  KATO Mitsuyasu (20194855)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  IMAMURA Takeshi (70264421)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 14 results
  • 4.  ICHIJO Hidenori (00242206)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  ISHIKAWA Fuyuki (30184493)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 6.  HIRAI Hisamaru (90181130)
    # of Collaborated Projects: 8 results
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  • 7.  MIYAGAWA Kiyoshi (40200133)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 8.  SASAZUKI Takehiko (50014121)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  AKIYAMA Tetsu (70150745)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 10.  HANAI Jun-ichi (70261964)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  WATABE Tetsuro (00334235)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 24 results
  • 12.  TAKAKU Fumimaro (40048955)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 13.  TOYOSHIMA Hideo (20197966)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 14.  KUROKI Toshio (90006073)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 15.  INAZAWA Johji (30193551)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 16.  MIYAZAWA Keiji (40209896)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 17.  KOINUMA Daizo (80375071)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 22 results
  • 18.  萩原 弘一 (00240705)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 19.  YAMADA Nobuhiro (40200729)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  SUGAMURA Kazuo (20117360)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  NAKAMURA Yusuke (70217909)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  HAMAJIMA Nobuyuki (30172969)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 23.  ABURATANI Hiroyuki (10202657)
    # of Collaborated Projects: 3 results
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  • 26.  EHATA Shogo (90506726)
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  • 32.  TAKATSU Kiyoshi (10107055)
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  • 33.  MINATO Nagahiro (40137716)
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  • 35.  HINO Okio (90127910)
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  • 36.  TOKINO Takashi (40202197)
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  • 37.  TAJIMA Kazuo (30150212)
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  • 38.  TSUGANE Shoichiro (40179982)
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  • 43.  TABATA Yasuhiko (50211371)
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  • 49.  TANIGUCHI Tadatsugu (50133616)
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  • 51.  貝淵 弘三 (00169377)
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  • 54.  越川 直彦 (70334282)
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  • 55.  SUGIMOTO Koichi
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  • 56.  TAKEDA Kohsuke
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  • 57.  SAITO Izumu (70158913)
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  • 61.  MUTO Tetsuichiro (20110695)
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  • 65.  KANO Mitsunobu (80447383)
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    # of Collaborated Products: 1 results
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  • 216.  徳久 剛史 (20134364)
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  • 217.  宮島 篤 (50135232)
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  • 232.  沖 俊一 (40264676)
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  • 233.  田中 亀代治 (80144450)
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  • 238.  千田 和弘 (00192188)
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  • 239.  大野 茂男 (10142027)
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  • 240.  清木 元治 (10154634)
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  • 246.  森川 真大 (80775833)
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  • 248.  赤木 蓉子 (70771004)
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  • 249.  CHIBA Shigeru
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  • 250.  細井 孝行
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 251.  本田 浩章
    # of Collaborated Projects: 1 results
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  • 252.  INUBUSHI Toshihiro
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  • 253.  丸山 一男
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    # of Collaborated Products: 1 results
  • 254.  丸山 淳子
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  • 255.  伊藤 友香
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  • 256.  田井中 一貴
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  • 257.  PODYMA Katarzyna Anna
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  • 258.  武井 華奈
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  • 259.  吉松 康裕
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  • 260.  堤 修一
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  • 261.  原田 浩
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  • 262.  小林 稔
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    # of Collaborated Products: 1 results
  • 263.  伊藤 博崇
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  • 264.  内橋 俊大
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  • 265.  久保田 晋平
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  • 266.  穂苅 諭
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    # of Collaborated Products: 1 results
  • 267.  古室 暁義
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    # of Collaborated Products: 1 results
  • 268.  浜嶋 信之
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    # of Collaborated Products: 1 results
  • 269.  菊地 利明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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