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SUGAMURA Kazuo  菅村 和夫

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Researcher Number 20117360
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Affiliation (based on the past Project Information) *help 2013 – 2015: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), その他部局等, その他
2014: 宮城県立がんセンター研究所, 特任部長
2011 – 2012: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), 発がん制御研究部, 特任部長
2011: 地方独立行政法人宮城県立病院機構 宮城県立がんセンター(研究所), 発がん制御研究部, 特任部長
2011: 宮城県立がんセンター研究所, 特任部長 … More
2011: 宮城県立がんセンター研究所, 発がん制御研究部, 特任部長
2010: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), 生化学部, 総長兼研究所長
2010: 宮城県立がんセンター, 総長
2009 – 2010: Tohoku University, 免疫学部, 総長
2009: 地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所), 総長兼研究所長
2007 – 2008: Tohoku University, 大学院・医学系研究科, 教授
2006: 東北大学, 医学系研究科, 教授
2006: Tohoku University, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授
2005: 東北大学, 大学院医学研究科, 教授
1999 – 2005: Tohoku University, Graduate School of Medicine, Professor, 大学院・医学系研究科, 教授
2001: 東北大学, 大学院・医学系研究所, 教授
2000: 東京医科歯科大学, 大学院・東北大学・医学研究科, 教授
1998 – 2000: 東北大学, 大学院・医学研究科, 教授
1986 – 1998: 東北大学, 医学部, 教授
1993: DEP.BACTERIO.TOHOKU.UNIV.PROFESSOR, 医学部, 教授
1986 – 1987: 東北大, 医学部, 教授 Less
Review Section/Research Field
Principal Investigator
Immunology / Virology / Biological Sciences / Virology / Functional basic dentistry / Tumor biology / Experimental pathology / Bacteriology (including Mycology)
Except Principal Investigator
Virology / Biological Sciences … More / 内科学一般 / Neurology / General surgery / Tumor biology / Pathological medical chemistry / Immunology / Virology / Obstetrics and gynecology / Cell biology Less
Keywords
Principal Investigator
IL-2 / ATL / IL-2 receptor / IL-2受容体 / HTLV-I / p40^<tax> / サイトカイン / ILー2受容体 / ILー2 / HTLVーI … More / 成人T細胞白血病 / OX40リガンド / γ鎖 / ヒト・パルボウイルス / Cキナーゼ / シグナル伝達 / パルボウイルス / 小胞輸送 / 転写活性化因子 / TPA / OX40 / T細胞補助シグナル / 炎症反応 / Inflammatory bowel disease / OX40L / apoptosis / 慢性関節リウマチ / 胎児水腫 / アポトーシス / XSCID / ELISA / 非免疫性胎児水腫 / tyrosine kinase / NK細胞 / 単クロン抗体 / 受容体サブユニット / フォルボールエステル / NOGマウス / オートファジー / B19 / 細胞周期 / HTLV-1 / Tax / HAM / cyclic AMP / protein kinase C / リン酸化蛋白 / 蛋白リン酸化 / cAMP / Inflammation / CD4 T cell / T cell costimulatory signal / vesicle trafficking / Cytokine / TCR / IL-7 / STAM / 制御性T細胞 / 自己免疫 / 蛋白分解 / Hrs / STAMs / γc鎖 / 抗原提示細胞 / 抗原提示 / CD4陽性T細胞 / 細胞内小胞輸送 / Linkage analysis / OX40 (CD134) / Leishmania major / OX40L遺伝子導入マウス / OX40L遺伝子欠損マウス / OX40リガンド(OX40L) / 寄生虫 / 免疫記憶 / ウイルス / サイトメガロウイルス / L.major / エフェクターT細胞 / T細胞 / OX40(CD134) / 遺伝子連鎖解析 / 炎症性腸疾患 / OX40 (CDI34) / Interstitial pneumonia / CD4^+ T cells / OX40L-transgenic mice / 自己免疫病 / OX40L欠損マウス / 抗DNA抗体 / IBD / 間質性肺炎 / OX40L導入マウス / G2 arrest / non-immune hydrops fetalis / NS1 / transgenic mice / Human parvovirus B19 / 細胞周期制御 / NS1非構造蛋白分子 / hydrops fetalis / rheumatoid arthritis / parvovirus / 伝染性紅斑 / リウマチ / knockout mice / T cell differntiation and growth / cytokine / interleukin 2 (IL-2) / JAK1,3 / γ鎖ノックアウトマウス / サイイトカイン / インターロイキン2 (IL-2) / ノックアウトマウス / チロシンキナーゼ / T細胞分化増殖 / インターロイキン2(IL-2) / Transplantation immunity / Monoclonal antibody / Immune suppression / 増殖シグナル / 可溶化型 / 免疫制御 / 移植免疫 / 免疫抑制 / high-affinity receptor / gamma chain / チロシンリン酸化 / immunofluorescence staining / polymerase chain reaction / Western blot / human parvovirus / アビジン・ビオチン / 蛍光抗体法 / ELISA法 / PCR / VPー1 / ヒトパルボウイルス / 血清診断 / 関節リウマチ / 免疫蛍光染色法 / 核酸重合反応法 / ウエスタンブロット法 / 免疫酵素法 / flow cytometry / monoclonal antibody / receptor subunits / monocytes / lymphocytes / チロシン・キナ-ゼ / CD8 / CD4 / 胸腺細胞 / フロ-サイトメトリ- / チロシンキナ-ゼ / 単球マクロファ-ジ / リンバ球 / ILー2レセプタ- / 組換えワクシニアウイルス / HTLV-Iキャリア / HLA / プロテアーゼ / pX / IL-2レセプター / 免疫不全マウス / 白血病 / Epithelial cellular adhesion molecule(EpCAM) / がん幹細胞 / 肝臓がん / 神経障害 / 細菌感染 / ヒト抗体 / 免疫不全 / ヒト型マウス / ヒト免疫 / IgGクラススイッチ / MHC class II / 免疫系ヒト化NOGマウス / HLA-DRトランスジェニックマウス / 免疫系ヒト化マウス / 免疫不全症 / ヒト化マウス / ヒト免疫系 / ニッチ / 記憶T細胞 / 細胞外環境 / T細胞恒常性維持 / LC3 / 細胞死 / ポリオウイルス / エンベロープ / MCMV / ウイルス増殖 / VHSドメイン蛋白 / DNAヘアピン構造 / 非構造蛋白NS1 / B19ウイルス / 赤芽球系細胞 / WAF1 / p21 / 細胞周期停止 / ヒトパルボウイルスB19 / SCIDマウス / トランスジェニックラット / トランスフォーメイション / 転写活性化 / HAMラット / トランスアクチベーション / 転写因子 / HILV-I感染ラット / HTLVーIキャリア-ラット / p27^<rex> / 機能ドメイン / 転写促進因子 / HTLVーIキャリア / 母子感染 / 感染防御 / 抗HTLVーI抗体 / DNA結合因子 … More
Except Principal Investigator
シグナル伝達 / サイトカイン / 細胞増殖 / NK細胞 / がん遺伝子 / signal transduction / がん抑制遺伝子 / リンホカイン / 癌 / HTLV-I / がん細胞 / 細胞死 / IL-2受容体 / ATL / ストロマ細胞 / PAI-1 / eotaxin / chemokine / endothelium / multiple sclerosis / MHC / apoptosis / cytokine / 細胞周期 / NMR / Oncogene / ウイルス発がん / リンホカイン・レセプター / IL-2 / LAK細胞 / 小胞輸送 / ライソソーム / 免疫病 / 抗原受容体 / Tax / アポトーシス / ヒトがん / がん転移 / 細胞分化 / 細胞間相互作用 / レセプター / ELISA / チロシンリン酸化 / エフェクター細胞 / サイトカインレセプター / Lymphokine / Immune Desponse / T Cell Growth / Tumor Antigen / Tumor Supressor Gene / Tumor Promoter / Viral Oncogene / リンフォカイン / 免疫応答 / T細胞の増殖 / 腫瘍抗原 / 発がんプロモ-タ- / autoantibody / T cell clone / B cell clone / anti-DNA antibody / 全身性エリテマトーデス / クローン / イディオタイプ / SLE(全身生エリテマトーデス) / 全身生エリテマトーデヌ / T細胞クローン / B細胞クローン / 全身性エリテユトーデス / 自己抗体 / B細胞クロン / T細胞クロン / 抗DNA抗体 / coordination / support / planning / advice / evaluation / Host r Response / Infection / 感染制御方法論 / 寄生虫感染 / 細菌感染 / ウイルス感染 / 研究推進 / 研究支援 / 企画実施 / 評価・助言 / 宿主応答 / 感染 / Chemokine / Multiple sclerosis / Th1 / South africa / Zambia / Southern africa / Africa / TB / AIDS / HIV infection / HIV / ジンバブエ / エイズ / 南アフリカ / ザンビア / 南部アフリカ / アフリカ / 結核 / 後天性免疫不全症候群 / HIV感染症 / IL-6 / CD95L / HSI / CD80, CD86 / CD40, CD40L / Gene Therapy / Drug Design / Cell Adhesion / Cell Cycle / Signal Transduction / Information Exchange / Cancer / International Scientific Research / 癌化学療法 / 癌遺伝子治療 / ドラッグデザイン / 情報交換 / 化学発癌 / 癌治療 / 細胞接着 / ウイルス発癌 / 遺伝子治療 / 薬品設計 / 細胞社会学 / 海外派遣 / 国際学術 / tumor suppressor gene / oncogene / human cancer / cancer metastasis / cell-cell interaction / cell differentiation / cell growth / 2国間共同研究 / ヒトゲノム / DNA修復 / skin allograft / anti-IL-2Rgamma antibody / anti-IL-2Rbeta antibody / anti-IL-2Ralpha antibody / IL-2 receptor / 皮膚移植延長効果 / 遊離IL-2受容体 / 細胞内刺激伝達抑制 / IL-2の吸収 / MLC / 抗γ鎖抗体 / モノクロナール抗体 / コモンγ鎖(γc) / インターロイキン2(IL-2) / costimulatory factor / antigen receptor / tolerance / lymphocyte lineage / クローナル除去 / リンパ球初期分化 / 補助因子受容体 / サイトカイン受容体 / 骨髄ストローマ / 補助刺激因子 / 免疫寛容 / リンパ球増殖分化 / Biosensor / Protein interaction / Gene targeting / Higher plants / Morphogenesis / Cre-loxP / Fission yeast / 植物 / 胚形成 / 蛋白高次機能構造 / 遺伝子ターゲティング / RNAプロセシング / バイオモニタリング / DNA再複製 / 温度感受性突然変異体 / ATPase / 免疫系 / バイオセンサー / 分子相互作用 / 遺伝子標的 / 高等植物 / 形態形成 / Cre-IoxP / 分裂酵母 / persistent infection / rheumatoid arthritis / human parvovirus / 多発性関節炎 / 持続感染 / ヒトパルボウイルスB19 / 慢性関節リウマチ / Transcriptional regulation / Growth control / Cancer cells / Tumor suppressor gene / Tumor promoter / Tumor virus / Information exchange / 研究集会 / 研究室訪問 / 北米 / 研究交流 / がん研究 / 転写調節 / 増殖制御 / 発がんプロモーター / 研究情報交換 / セリンエステラーゼ / 慢性B白血病細胞 / NK骨髄腫細胞 / CTL / リンパ球の白血病化 / 白血病 / 遺伝子発現制御 / 骨髄幹細胞 / IL-5 / IL-3 / 細胞骨格蛋白 / 細胞表面燐酸化チロシン蛋白 / 細胞増殖因子 / 癌化機構 / 燐酸化チロシン / 遺伝子発現 / ILー5,NK細胞 / ILー3 / ILー2 / ヘルパーT細胞 / T細胞因子:マクロファージ / 抗腫瘍免疫 / 抗体遺伝子 / プレB細胞株 / HTLV-1(PX) / IL-2レセプター / Bリンパ球増殖因子 / TRF / BCGF【II】 / BSF2 / リンホトキシン / IL4 / IL3 / IL2 / T細胞因子 / 遅延型T細胞 / キラーT細胞 / マクロファージ / 腫瘍免疫 / 胆道癌 / CD274 / がん幹細胞 / 2重基質ボスファターゼ / 2重基質ホスファターゼ / 2重基質ホスファターゼ / ホスファターゼ / KIF3 / キネシンモーター / 分子腫瘍学 / TLR / 蛋白質分解 / 自然免疫 / スパイク / 偽ウイルス / ACE2 / コロナウイルス / 細胞内侵入 / 共受容体 / ウイルス / SARS / 小胞体輸送 / ノックアウトマウス / ユビキチン / マウス / Hrs / プロテアソーム / ポリユビキチン / カーゴ / エスコート / コロニー形成 / エンドソーム / 発がん / 小胞 / VHS / Tcell / activation / TSP / HAM / inflammatory myopathy / thymus / T cell / lymphocyte / HAM TSP / gp34 / OX40 / 情報伝達 / 免疫異常 / 増殖抑制 / STAT / リンパ球 / トランスアクチベーション / コモンγ鎖 / RNA結合蛋白 / NF-kB / トランスアクチペ-タ / アボトーシス / 細胞生物学 / 転移 / 分化 / 増殖 / 遺伝子 / がん / ウエスタンブロット / 単クロン抗体 / ヒトパルボウイルス / GTP結合蛋白質 / 脂質メディエーター / 細胞機能発現 / 生理活性分子 / 細胞接着分子 / 細胞内シグナル伝達 / γ鎖 / 組換えVP-1 / ヒト・パルボウイルス / 抗レセプタ-抗体 / 異常増殖 / T細胞 / エフェクタ-細胞 / シグナル伝達機構 / サイトカイン レセプタ- / B白血病細胞 / 骨髄腫細胞 / T細胞抗原受容体 / ナチュラルキラー細胞 / 細胞傷害性T細胞 / リンパ球の分化 / 遺伝子発現調節 / オートクリン機構 / T細胞抗原レセプター遺伝子 / IL5受容体 / IL2受容体 Less
  • Research Projects

    (67 results)
  • Research Products

    (92 results)
  • Co-Researchers

    (308 People)
  •  Analysis of transformation processes by using the "two-hit leukemogenesis model"Principal Investigator

    • Principal Investigator
      Sugamura Kazuo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Tumor biology
    • Research Institution
      Miyagi Prefectural Hospital Organization Miyagi Cancer Center
  •  Role of CD274 in cancer stem cell of cholangicarcinoma

    • Principal Investigator
      SHIINA Masaaki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Miyagi Prefectural Hospital Organization Miyagi Cancer Center
  •  Regulation of KIF3 motor by dephosphorylation

    • Principal Investigator
      SHIMA Hiroshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  Mechanism of SARS coronavirus infection and proliferation

    • Principal Investigator
      TANAKA Nobuyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      地方独立行政法人宮城県立病院機構宮城県立がんセンター(研究所)
      Miyagi Cancer Center Research Institute
  •  Signal transduction of TLR by STM/Hrs

    • Principal Investigator
      MURATA Kazuko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Immunology
    • Research Institution
      Iwaki Meisei University
  •  高感度腫瘍正着NOGマウスを用いた肝がん幹細胞の同定および治療基盤の確立Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Experimental pathology
    • Research Institution
      Miyagi Cancer Center Research Institute
  •  A fundamental research for developing ubiquitin-targeted cancer therapies utilizing vesicular transport related molecules Hrs knocked-out mice.

    • Principal Investigator
      YAEGASHI Nobuo
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Obstetrics and gynecology
    • Research Institution
      Tohoku University
  •  Establishment of humanized immune mice and its application for study of human immune system of human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemof human immune systemofPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2007 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      地方独立行政法人宮城県立病院機構 宮城県立がんセンター(研究所)
      Miyagi Cancer Center Research Institute
      Tohoku University
  •  STAMs/Hrs複合体を介したオートファジー依存性細菌感染防御Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Tohoku University
  •  T細胞免疫記憶に関する細胞外環境の解析Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  ウイルス感染による細胞周期停止に伴う細胞死誘導メカニズムPrincipal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  新規小胞輸送蛋白質複合体Hrs・STAMsによるがん抑制機構

    • Principal Investigator
      TANAKA Nobuyuki
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  遺伝子ノックアウトを用いた新規クラスE分子群による小胞輸送の研究

    • Principal Investigator
      田中 伸幸
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  小胞輸送に関わる新規VHSドメイン蛋白分子群によるウイルス増殖制御Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  パルボウイルスB19によるG2期停止/アポトーシス誘導機構と宿主特異性因子の研究Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  Signal transducing pathways in immune cells and immunological disorders caused by their dysfunctionsPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2002 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  Molecular Bases underlying Microbial Infections and the Host Responses

    • Principal Investigator
      NAGAI Yoshiyuki
    • Project Period (FY)
      2001 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
      Toyama Institute of Health
      Nagoya University
  •  Regulation of infectious immunity by the OX40-0X4OL systemPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2001 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tohoku University
  •  Analysis of transgenic mice expressing human parvovirus non-stractual (NS1) proteinPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  Regulation of autoimmune diseases by OX40-OX40L interactPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  がんの生物学的特性の研究の総括

    • Principal Investigator
      SASAZUKI Takehiko, KUROKI Toshio
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
      Showa University
      The University of Tokyo
  •  Molecular epidemiology of HIV/AIDS and related diseases in Southern Africa

    • Principal Investigator
      YAMAMOTO Naoki
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical Dental University
  •  Establishment of Model Mice of Rheumatoid Arthritis by using nonstructural protein 1 (NS1) of parvovirus B19Principal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  多発性硬化症におけるケモカインシグナル伝達系の検討

    • Principal Investigator
      ONODERA Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      TOHOKU UNIVERSITY
  •  情報伝達とリンパ球の機能分化

    • Principal Investigator
      宮園 浩平
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Japanese Foundation For Cancer Research
  •  HAMの臨床免疫学的病態における異常リンパ球活性化機構とOX40,gp34の役割

    • Principal Investigator
      ITOYAMA Yasuto
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Immune regulation and signal tranduction

    • Principal Investigator
      OKUMURA Ko
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Juntendo University School of Medicine
  •  HTLV-I Taxと結合するRNA結合分子と転写因子の作用

    • Principal Investigator
      中村 正孝
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tokyo Medical and Dental University
  •  HTLV-1による細胞がん化の分子機構Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  HTLV-1 Taxに結合する未知細胞因子の転写促進機能

    • Principal Investigator
      中村 正孝
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  Cooperation and information exchange with European countries.

    • Principal Investigator
      KUROKI Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Showa University
      The University of Tokyo
  •  Information Exchange on Cancer Research with North American

    • Principal Investigator
      YAMAMOTO Tadashi
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokyo
  •  Study of mechanism of X-licombined immunodeficiency caused by mutations of the IL-2 receptor gamma chainPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  HTLV-I感染細胞の増殖癌化の分子機構Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  γ鎖とチロシンキナーゼを含むIL-2受容体コンプレックスの機能解析

    • Principal Investigator
      中村 正孝
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  サイトカインと細胞接着分子による細胞内シグナル伝達ネットワークの研究

    • Principal Investigator
      新井 賢一
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      Cell biology
    • Research Institution
      The University of Tokyo
  •  ヒトパルボウイルスB19のレセプターの検索

    • Principal Investigator
      中村 正孝
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  Regulation of Gene Expression

    • Principal Investigator
      TANIGUCHI Masaru
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Chiba University
  •  Molecular mechnisms of immune tolerance.

    • Principal Investigator
      HIRANO Toshio
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Development of immunosuppressant drugs based on inhibition of IL-2 functionPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Three Subunits of IL-2 Receptor

    • Principal Investigator
      SATOMI Susumu
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  HTLV-I感染細胞の増殖癌化の分子機構Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  ヒト・パルボウイルスB19の病因論に関する研究

    • Principal Investigator
      NAKAMURA Masataka
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Tohoku University
  •  The role of human parvovirus infection in rheumatoid arthritis

    • Principal Investigator
      SASAKI Takeshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      TOHOKU UNIVERSITY
  •  HTLVーI感染細胞の増殖癌化の分子機構Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  Information Exchange on Cancer Research with North American Countries.

    • Principal Investigator
      YAMAGUCHI Nobuo
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Institute of Medical Science, University of Tokyo
  •  Expression of interleukin 2 receptor subunits and mechanism of T cell growthPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      TOHOKU UNIVERSITY
  •  成人T細胞白血病と病因ウイルスPrincipal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  エフェクタ-細胞の機能分化:サイトカインとそのレセプタ-系を中心にしたアプロ-チ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  成人T細胞白血病と病因ウイルスPrincipal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  リンパ球の増殖・分化の制御及びその白血病化についての分子生物学的研究

    • Principal Investigator
      WATANABE Takeshi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  エフェクター細胞の機能分化;サイトカインとそのレセプター系を中心としたアプローチ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  The Role of IL-2 Receptor Alpha and Beta Chain in Growth and Differentiation of LymphocytesPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Tohoku University
  •  Development of diagnostic methods for human parvovirus infectionPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Virology
    • Research Institution
      Tohoku Univeristy
  •  成人T細胞白血病と病因ウイルスPrincipal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  リンパ球の増殖・分化の制御およびその白血病化について分子生物学的研究

    • Principal Investigator
      渡辺 武
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  エフェクター細胞の機能分化:サイトカインとそのレセプター系を中心にしたアプローチ

    • Principal Investigator
      高津 聖志
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kumamoto University
  •  Information Exchange on Cancer Research with North American Countries

    • Principal Investigator
      YAMAGUCHI Nobuo, 河井 貞明
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute of Medical Science, The University of Tokyo
  •  リンパ球の増殖,分化の制御およびその白血病化についての分子生物学的研究

    • Principal Investigator
      渡辺 武
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kyushu University
  •  発癌と細胞増殖制御における燐酸ヒチロシン蛋白の役割

    • Principal Investigator
      渡辺 泰
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tokai University
  •  ヒト・レトロウイルスによるT細胞腫瘍化機構:フォルボールエステル受容体の役割Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  Study of the signal transduction mechanism for IL-2-induced T cell growthPrincipal Investigator

    • Principal Investigator
      SUGAMURA Kazuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  T細胞因子による抗腫瘍免疫の調節機構に関する研究

    • Principal Investigator
      熊谷 勝男
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  リンフォカインとそのアクセプターに関する免疫学的及び分子生物学的研究

    • Principal Investigator
      KISHIMOTO Tadamitsu
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Osaka University
  •  ヒト・レトロウイルスのT細胞腫瘍化における2段階機構の解析Principal Investigator

    • Principal Investigator
      菅村 和夫
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  T細胞因子による抗腫瘍免疫の調節機構に関する研究

    • Principal Investigator
      熊谷 勝男
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Tohoku University
  •  Analysis of regulatory mechanism for autoantibody production by using human T and B cell clones.

    • Principal Investigator
      SASAKI Takeshi
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      TOHOKU UNIVERSITY

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2005 2004 2003 2001 1999 1998 Other

All Journal Article Presentation Book

  • [Book] Encyclopedia of Endocrine Diseases2004

    • Author(s)
      Tanaka, N., Sugamura K.
    • Total Pages
      603
    • Publisher
      Elsevier Inc.
    • Data Source
      KAKENHI-PROJECT-16044203
  • [Book] Encyclopedia of Endocrine Diseases2004

    • Author(s)
      Tanaka, N., Sugamura K.
    • Total Pages
      603
    • Publisher
      Elsevier Inc.
    • Data Source
      KAKENHI-PROJECT-16021202
  • [Book] Encyclopedia of Endocrine Diseases2004

    • Author(s)
      Tanaka, N., Sugamura K.
    • Total Pages
      603
    • Publisher
      Elsevier Inc.
    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Xenotransplantation elicits salient tumorigenicity of adult T-cell leukemia-derived cells via aberrant AKT activation.2016

    • Author(s)
      Yamaguchi K, Takanashi T, Nasu K, Tamai K, Mochizuki M, Satoh I, Ine S, Sasaki O, Satoh K, Tanaka N, Harigae H, Sugamura K.
    • Journal Title

      Cancer Sci.

      Volume: ePub Issue: 5 Pages: 638-643

    • DOI

      10.1111/cas.12921

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K06848, KAKENHI-PROJECT-26830087, KAKENHI-PROJECT-26861427, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-15K14414, KAKENHI-PROJECT-16K20290
  • [Journal Article] Identification of TL-Om1, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR.2015

    • Author(s)
      Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I.
    • Journal Title

      Journal of Clinical Microbiology

      Volume: 53 Issue: 2 Pages: 587-596

    • DOI

      10.1128/jcm.02254-14

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J06916, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-24591414, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25860798, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06848, KAKENHI-PROJECT-25461440
  • [Journal Article] OX40 and IL-7 play synergistic roles in the homeostatic proliferation of effector memory CD4+ T cells.2014

    • Author(s)
      Yamaki S, Ine, S, Kawabe T, Okuyama Y, Suzuki N, Soroosh P, Mousavi SF, Nagashima H, Sun S-L, So T, Sasaki T, Harigae H, Sugamura K, Kudo H, Wada M, Nio M, and Ishii N.
    • Journal Title

      European Journal of Immunology

      Volume: 44 Issue: 10 Pages: 3015-3025

    • DOI

      10.1002/eji.201444701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-14J06157, KAKENHI-PROJECT-24390118, KAKENHI-PROJECT-25290047
  • [Journal Article] Hepatocyte growth factor regulated tyrosine kinase substrate in the peripheral development and function of B-cells.2014

    • Author(s)
      Nagata T, Murata K, Murata R, Sun SL, Saito Y, Yamaga S, Tanaka N, Tamai K, Moriya K, Kasai N, Sugamura K, Ishii N.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 443 Pages: 351-356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Journal Article] Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinoma2014

    • Author(s)
      Keiichi Tamai, Mao Nakamura, Masamichi Mizuma, Mai Mochizuki, Misa Yokoyama, Hiroyuki Endo, Kazunori Yamaguchi, Takayuki Nakagawa, Masaaki Shiina, Michiaki Unno, Koji Muramoto, Ikuro Sato, Kennichi Satoh, Kazuo Sugamura, and Nobuyuki Tanaka
    • Journal Title

      Cancer Science

      Volume: 105 Issue: 6 Pages: 667-674

    • DOI

      10.1111/cas.12406

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25640073, KAKENHI-PROJECT-25860572, KAKENHI-PROJECT-26861427
  • [Journal Article] Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer.2014

    • Author(s)
      Abue, M., Yokoyama, M., Shibuya, R., Tamai, K., Yamaguchi, K., Sato, I., Tanaka, N., Hamada, S., Shimosegawa, T., Sugamura, K., Satoh, K.
    • Journal Title

      Int J Oncol

      Volume: 10 Issue: 2 Pages: 1-9

    • DOI

      10.3892/ijo.2014.2743

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24591022, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25670591, KAKENHI-PROJECT-25430163
  • [Journal Article] Enhanced expression of long non-coding RNA HOTAIR is associated with the development of gastric cancer.2013

    • Author(s)
      Endo H, Shiroki T, Nakagawa T, Yokoyama M, Tamai K, Yamanami H, Fujiya T, Sato I, Yamaguchi K, Tanaka N, Iijima K, Shimosegawa T, Sugamura K, Satoh K.
    • Journal Title

      PlosONE

      Volume: 8 Issue: 10 Pages: e77070-e77070

    • DOI

      10.1371/journal.pone.0077070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-24300326, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24591022, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-24791480, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25860572
  • [Journal Article] Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector2013

    • Author(s)
      Horino S, Uchiyama T, So T, Nagashima H, Sun SL, Sato M, Asao A, Haji Y, Sasahara Y, Candotti F, Tsuchiya S, Kure S, Sugamura K, and Ishii N
    • Journal Title

      PLoS ONE

      Volume: 8 Issue: 8 Pages: e71594-e71594

    • DOI

      10.1371/journal.pone.0071594

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J06848, KAKENHI-PROJECT-24659486, KAKENHI-PROJECT-24659487, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25860836
  • [Journal Article] Regulation of hepatitis C virus secretion by the Hrs-dependent exosomal pathway2012

    • Author(s)
      Tamai K, Shiina M, Tanaka N, Nakano T, Yamamoto A, Kondo Y, Kakazu E, Inoue J, Fukushima K, Sano K, Ueno Y, Shimosegawa T, Sugamura K.
    • Journal Title

      Virology

      Volume: 422(2) Pages: 377-85

    • Data Source
      KAKENHI-PROJECT-21590517
  • [Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/ γ cnull mouse.2012

    • Author(s)
      Suzuki M, Takahashi T, Katano T, Ito R, Ito M, Harigae H, Ishii N, Sugamura K.
    • Journal Title

      Int. Immunol.

      Volume: 24 Pages: 243-252

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] AMSH is required to degrade ubiquitinated proteins in the central nervous system2011

    • Author(s)
      Suzuki, S.; Tamai, K.; Watanabe, M., et al
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 408(2) Issue: 4 Pages: 582-588

    • DOI

      10.1016/j.bbrc.2011.04.065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19100005, KAKENHI-PROJECT-21590517, KAKENHI-PROJECT-22590713, KAKENHI-PROJECT-22591925, KAKENHI-PROJECT-22790630
  • [Journal Article] AMSH is required to degrade ubiquitinated proteins in the central nervous system2011

    • Author(s)
      Suzuki S, Tamai K, Sugamura K, Tanaka N.他(7人中7番目)
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 408(4) Pages: 582-8

    • Data Source
      KAKENHI-PROJECT-21590517
  • [Journal Article] AMSH is required to degrade ubiquitinated proteins in the central nervous system2011

    • Author(s)
      Suzuki, S, Tamai, K, Watanabe, M, Kyuuma, M, Ono, M, Sugamura, K., Tanaka, N.
    • Journal Title

      Biochem.Biophy.Res.Comm.

      Volume: 408 Pages: 582-588

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Angiotensin II type 1 receptor expression and microvessel density in human bladder cancer2011

    • Author(s)
      Amano Y, Yamashita Y, Tanaka N, Sugamura K, 他(7人中5番目)
    • Journal Title

      J Biol Chem

      Volume: 286(17) Pages: 15458-72

    • Data Source
      KAKENHI-PROJECT-21590517
  • [Journal Article] Hrs recognizes a hydrophobic amino acid cluster in cytokine receptors during ubiquitin-independent endosomal sorting2011

    • Author(s)
      Amano Y, Yamashita Y, Tanaka N, Sugamura K, 他
    • Journal Title

      J Biol Chem

      Volume: 286 Issue: 17 Pages: 15458-15472

    • DOI

      10.1074/jbc.m110.191924

    • NAID

      120007110518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590517, KAKENHI-PROJECT-21590530, KAKENHI-PROJECT-22591925
  • [Journal Article] Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension2011

    • Author(s)
      Rabieyousefi, M., Soroosh, P., Satoh, K., Date, F., Ishii, N., Yamashita, M., Oka, M., Shimokawa, M., Nose, M., Sugamura, K., Ono, M.
    • Journal Title

      BMC Immunology

      Volume: 12 Pages: 67-67

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] In vivo assay of human NK-dependent ADCC using NOD/SCID/γc^<null> (NOG) mice.2010

    • Author(s)
      Shiokawa, M., Takahashi, T., Murakami, A., Kita, S., lto, M., Sugamura, K. and Ishii, N.
    • Journal Title

      Biochem.Biophy. Res. Comm.

      Volume: 399 Pages: 733-737

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Characterization of the EpCAM^+ cell population in hepatocellular carcinoma cell lines2010

    • Author(s)
      Kimura, 0., Takahashi, T., Ishii, N., Inoue, Y., Ueno, Y., Kogure, T., Fukushima, K., Shiina, M., Yamagiwa, Y., Kondo, Y., Inoue, J., Kakazu, E., Iwasaki, T., Kawagishi, N., Shimosegawa, T., and Sugamura, K
    • Journal Title

      Cancer Sci.

      Volume: 101 Pages: 2145-2155

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] In vivo assay of human NK-dependent ADCC using NOD/SCID/γc^<null> (NOG) mice2010

    • Author(s)
      Shiokawa, M., Sugamura, K., et al.
    • Journal Title

      Biochem.Biophy.Res.Comm.

      Volume: 399 Pages: 733-737

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein2010

    • Author(s)
      Tamai K, Tanaka N, Sugamura K., 他(13人中2番目)
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 399(3) Pages: 384-90

    • Data Source
      KAKENHI-PROJECT-21590517
  • [Journal Article] Regulatory T cells are necessary for implantation and maintenance of early pregnancy but not ate pregnancy in allogeneic mice.2010

    • Author(s)
      Shima, T., Sasaki, Y., Itoh, M., Nakashima, A., Ishii, N., Sugamura, K. and Saito, S.
    • Journal Title

      J. Rep. Immunol.

      Volume: 85 Pages: 121-129

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein.2010

    • Author(s)
      Tamai, K., Sugamura, K., et al.
    • Journal Title

      Biochem.Biophy.Res.Comm.

      Volume: 399 Pages: 384-390

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Induction of class switch IgG response in vitro in human B cells developed in humanized NOD/shi-scid/γc^<null>(NOG)mice : Differentiation of IgM^+IgD^+ mature B cells and unusual emergence of B-cell progenitors2009

    • Author(s)
      Watanabe, Y., Takahashi, T., Ishii, N., Ito, M., Minegishi, M., Tsuchiya, S., Sugamura, K
    • Journal Title

      Int.Immunol. 21巻

      Pages: 843-858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659096
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, Okajima A, Shiokawa M, Ishii N, Katano I, Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S, Sugamura K
    • Journal Title

      Int Immunol

      Volume: 21 Pages: 843-858

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/{gamma}cnull(NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, 0kajima A, Shiokawa M, Ishii N, Katano I,Ito R, Ito M, Minegishi M, Minegishi N, Tsuchiya S and Sugamura K.
    • Journal Title

      Int. Immunol.

      Volume: 21 Pages: 843-858

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Generation of a syngeneic mouse model to study the intraperitoneal metastasis of ovarian cancer with in vivo luciferase imaging.2009

    • Author(s)
      Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K, Yaegashi N.
    • Journal Title

      Luminescence. 24

      Pages: 324-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390428
  • [Journal Article] Generation of a syngeneic mouse model to study the intraperitoneal metastasis of ovarian cancer with in vivo luciferase imaging.2009

    • Author(s)
      Toyoshima M, Tanaka Y, Matumoto M, Yamazaki M, Nagase S, Sugamura K, Yaegashi N
    • Journal Title

      Luminescence 24

      Pages: 324-331

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390428
  • [Journal Article] The analysis of the functions of human B and T cells in humanized NOD/shi-scid/gammac(null) (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Watanabe Y, Takahashi T, Ito M, Sugamura K, et al
    • Journal Title

      Int. Immunol. 21

      Pages: 843-858

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Loss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration.2008

    • Author(s)
      Tamai K, Toyoshima M, Tanaka N, Yamamoto N, Owada Y, Kiyonari H, Murata K, Ueno Y, Ono M, Shimosegawa T, Yaegashi N, Watanabe M, Sugamura K.
    • Journal Title

      Am J Pathol. 173

      Pages: 1806-1817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390428
  • [Journal Article] Loss of Hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration2008

    • Author(s)
      Tamai, K., Toyoshima, M., Tanaka, N., Yamamoto, N., Owada Y., Kiyonari, H., Murata, K., Ueno, Y., Ono, M., Shimosegawa, T., Yaegashi, N., Watanabe, M. and Sugamura, K.
    • Journal Title

      Am. J. Pathol 173

      Pages: 1806-1817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659108
  • [Journal Article] Endosomal sorting complex required for transport proteins in cancer pathogenesis, vesicular transport, and non-endosomal functions2008

    • Author(s)
      Tanaka, N., Kyuma, M. and Sugamura, K.
    • Journal Title

      Cancer Science 99

      Pages: 1293-1303

    • NAID

      10024007871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659108
  • [Journal Article] c-Cbl-dependent monoubiquitination and lysosomal degradation of gp1302008

    • Author(s)
      Tanaka, Y., Tanaka, N., Saeki, Y., Tanaka, K., Murakami, M., Hirano, T., Ishii, N. and Sugamura, K.
    • Journal Title

      Mol. Cell. Biol 28

      Pages: 4805-4818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19659108
  • [Journal Article] Hrs, a mammalian master molecule in vesicular transport and protein-sorting, suppresses the degradation of ESCRT proteins STAM1 and STAM2.2005

    • Author(s)
      Kobayashi H, Sugamura K.ほか
    • Journal Title

      J.Biol.Chem (印刷中)

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Positional identification of TNFSF4,encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.2005

    • Author(s)
      Wang, X., Ishii, N., Sugamura, K.ほか
    • Journal Title

      Nat.Genet (印刷中)

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.2005

    • Author(s)
      Wang, X., Sugamura, K.ほか
    • Journal Title

      Nat.Genet. (In press)

    • Data Source
      KAKENHI-PROJECT-16044203
  • [Journal Article] Hrs, a Mammalian Master Molecule in Vesicular Transport and Protein Sorting, Suppresses the Degradation of ESCRT Proteins Signal Transducine Adaptor Molecule 1 and 22005

    • Author(s)
      Tanaka N., Sugamura, K.ほか
    • Journal Title

      Journal of Biological Chemistry 280

      Pages: 10468-10477

    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.2005

    • Author(s)
      Wang, X., Sugamura, K.ほか
    • Journal Title

      Nat.Genet. (In press)

    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Hrs, a mammalian master molecule in vesicular transport and protein-sorting, suppresses the degradation of ESCRT proteins STAM1 and STAM2.2005

    • Author(s)
      Kobayashi H, Sugamura K.ほか
    • Journal Title

      The Journal of Biological Chemistry 280

      Pages: 10468-10477

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility.2005

    • Author(s)
      Wang, X., Sugamura Kほか
    • Journal Title

      Nat.Genet (印刷中)

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Positional identification of TNFSF4,encoding OX40 ligand, as a gene that in fluences atherosclerosis susceptibility.2005

    • Author(s)
      Wang, X., Sugamura, K.ほか
    • Journal Title

      Nat.Genet. (In press)

    • Data Source
      KAKENHI-PROJECT-16021202
  • [Journal Article] Expanding role of T-cell costimulators in regulatory T-cellfunction : recent advances in accessory molecules expressed onboth regulatory and non-regulatory T cells.2004

    • Author(s)
      Ndhlovu, L.C., Ishii, N., Sugamura K.ほか
    • Journal Title

      Crit.Rev.Immunol 24

      Pages: 251-266

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunnization.2004

    • Author(s)
      Kato, H., Kojima, H., Ishii, N., Hase, H., Imai, Y., Fujibayashi, T., Sugamura, K., Kobata, T.
    • Journal Title

      J.Clip.Immunol. 24(3)

      Pages: 237-248

    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Therapeutic targeting of the effector T cell costimulatory molecule OX40.2004

    • Author(s)
      Sugamura, K.ほか
    • Journal Title

      Nat.Rev.Immunol. 4

      Pages: 420-431

    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Human parvovirus B19 nonstructural protein transactivates the p21/WAF1 through Sp1.2004

    • Author(s)
      Nakajima, A., Morita, E., Saito, S., Sugamura, K.
    • Journal Title

      Virology 329(2)

      Pages: 493-504

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Distinct roles for the OX40-OX40L interaction regulatory and non-regulatory T cells.2004

    • Author(s)
      Takeda, I., Ishii, N., Sugamura K.ほか
    • Journal Title

      J.Immunol. 172

      Pages: 3580-3589

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Expanding role of T-cell costimulators in regulatory T-cellfunction : recent advances in accessory molecules expressed onboth regulatory and non-regulatory T cells.2004

    • Author(s)
      Ndhlovu, L.C., Sugamura, K.ほか
    • Journal Title

      Crit.Rev.Immunol. 24

      Pages: 251-266

    • Data Source
      KAKENHI-PROJECT-16044203
  • [Journal Article] Adenovirus vector-mediated in vivo gene transfer of OX40 ligand to tumor cells enhances anti-tumor immunity of tumor-bearing hosts.2004

    • Author(s)
      Andarini, S., Ishii, N., Sugamura, K.ほか
    • Journal Title

      Cancer Res. 64

      Pages: 3281-3287

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Expanding role of T-cell costimulators in regulatory T-cell function : recent advances in accessory molecules expressed on both regulatory and non-regulatory T cells.2004

    • Author(s)
      Ndhlovu, L.C., Sugamura, K.ほか
    • Journal Title

      Crit.Rev.Immunol. 24

      Pages: 251-266

    • Data Source
      KAKENHI-PROJECT-16021202
  • [Journal Article] Therapeutic targeting of the effector T cell costimulatory molecule OX40.2004

    • Author(s)
      Sugamura, K. ほか
    • Journal Title

      Nat.Rev.Immunol. 4

      Pages: 420-431

    • Data Source
      KAKENHI-PROJECT-16044203
  • [Journal Article] Expanding role of T-cell costimulators in regulatory T-cellfunction : recent advances in accessory molecules expressed onboth regulatory and non-regulatory T cells.2004

    • Author(s)
      Ndhlovu, L.C., Sugamura K.ほか
    • Journal Title

      Crit.Rev.Immunol 24

      Pages: 251-266

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Adenovirus vector-mediated in vivo gene transfer of OX40 ligand to tumor cells enhances anti-tumor immunity of tumor-bearing hosts.2004

    • Author(s)
      Andarini, S., Sugamura K.ほか
    • Journal Title

      Cancer Res. 64

      Pages: 3281-3287

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunizations.2004

    • Author(s)
      Kato, H., Sugamura, K.ほか
    • Journal Title

      J.Clin.Immunol. 24

      Pages: 237-248

    • Data Source
      KAKENHI-PROJECT-16021202
  • [Journal Article] Human parvovirus B19 nonstructural protein transactivates the p21/WAF1 through Spl.2004

    • Author(s)
      Nakajima, A., Morita, E., Saito, S., Sugamura K.
    • Journal Title

      Virology 329 (2)

      Pages: 493-504

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Distinct roles for the OX40-OX40L interaction regulatory and non-regulatory T cells.2004

    • Author(s)
      Takeda, I., Sugamura K.ほか
    • Journal Title

      J.Immunol. 172

      Pages: 3580-3589

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Therapeutic targeting of the effector T cell costimulatory molecule OX402004

    • Author(s)
      Sugamura, K., Ishii, N., Weinberg, AD
    • Journal Title

      Nat.Rev.Immunol. 4

      Pages: 420-431

    • Data Source
      KAKENHI-PROJECT-14104011
  • [Journal Article] Therapeutic targeting of the effector T cell costimulatory molecule OX402004

    • Author(s)
      Sugamura, K., Ishii, N., Weinberg, A.D
    • Journal Title

      Nat.Rev.Immunol. 4

      Pages: 420-431

    • Data Source
      KAKENHI-PROJECT-13226006
  • [Journal Article] Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunizations.2004

    • Author(s)
      Kato, H., Sugamura, K.ほか
    • Journal Title

      J.Clin.Immunol. 24

      Pages: 237-248

    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Expanding role of T-cell costimulators in regulatory T-cell function : recent advances in accessory molecules expressed on both regulatory and non-regulatory T cells.2004

    • Author(s)
      Ndhlovu, L.C., Sugamura, K.ほか
    • Journal Title

      Crit.Rev.Immunol. 24

      Pages: 251-266

    • Data Source
      KAKENHI-PROJECT-16659118
  • [Journal Article] Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunnization.2004

    • Author(s)
      Kato, H., Kojima, H., Ishii, N., Hase, H., Imai, Y., Fujibayashi, T., Sugamura, K., Kobata, T.
    • Journal Title

      J. Clin. Immunol. 24(3)

      Pages: 237-248

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Therapeutic targeting of the effector T cell costimulatory molecule OX40.2004

    • Author(s)
      Sugamura, K.ほか
    • Journal Title

      Nat.Rev.Immunol. 4

      Pages: 420-431

    • Data Source
      KAKENHI-PROJECT-16021202
  • [Journal Article] Essential role of OX4OL on B cells in persistent alloantibody production following repeated alloimmunnization.2004

    • Author(s)
      Kato, H., Kojima, H., Ishii, N., Hase, H., Imai, Y., Fujibayashi, T., Sugamura K., Kobata, T.
    • Journal Title

      1. Clin. Immunol. 24 (3)

      Pages: 237-248

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Essential role of OX40L on B cells in persistent alloantibody production following repeated alloimmunizations.2004

    • Author(s)
      Kato, H., Sugamura, K.ほか
    • Journal Title

      J.Clin.Immunol. 24

      Pages: 237-248

    • Data Source
      KAKENHI-PROJECT-16044203
  • [Journal Article] OX40 (CD134) and OX40 ligand interaction plays an adjuvant role during in vivo Th2 responses.2003

    • Author(s)
      Ishii N, Ndhlovu LC, Murata K, Sato T, Kamanaka M, Sugamura K.
    • Journal Title

      Eur J Immunol. 33(9)

      Pages: 2372-2381

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis.2001

    • Author(s)
      Ndhlovu LC, Ishii N, Murata K, Sato T, Sugamura K.
    • Journal Title

      J Immunol. 167(5)

      Pages: 2991-2999

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Loss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice.2001

    • Author(s)
      Ishii N, Owada Y, Yamada M, Miura S, Murata K, Asao H, Kondo H, Sugamura K.
    • Journal Title

      Mol. Cell. Biol. 21(24)

      Pages: 8626-8637

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13225001
  • [Journal Article] Serologic Study of Human Parvovirus B19 Infection in Pregnancy in Japan,1999

    • Author(s)
      Yaegashi, N., Niinuma, T., Chisaka, H., Uehara, S., Okamura, K., Shinkawa, O., Tsunoda, A., Moffatt, S., Sugamura, K.Yajima, A.
    • Journal Title

      J.Infection Vol.38

      Pages: 30-35

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10470074
  • [Journal Article] Parvovirus B19 induces poptosis of erythroid cells in vitro and in vivo.1999

    • Author(s)
      Yaegashi, N., Niinuma, T., Chisaka, H., Uehara, S., Moffatt, S., Tada, K., Iwabuchi, M., Matsunaga Y., Nakayama, M., Yutani, C., Osamura, Y., Hirayama, E., Okamura, K., Sugamura, K., Yajima, A.
    • Journal Title

      J.Infection Vol.39

      Pages: 68-76

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10470074
  • [Journal Article] Human parvovirus B19 as a causative agent for rheumatoid arthritis.1998

    • Author(s)
      Takahashi, Y., Murai, C., Shibata, S., Munakata, Y., Ishii, T., Ishii, K., Saitoh, T., Sawai, T., Sugamura, K., Sasaki, T.
    • Journal Title

      Proc.Natl.Acad.Sci.USA, Vol.95, 14

      Pages: 8227-8232

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-10470074
  • [Journal Article] Development of a multi-step leukemogenesis model of MLL-rearranged leukemia using humanized mice.

    • Author(s)
      Moriya, K., Suzuki, M., Watanabe, Y., Takahashi, T., Aoki, Y., Uchiyama, T., Kumaki, S., Sasahara, Y., Minegishi, M., Kure, S., Tsuchiya, S., Sugamura, K. and Ishii, N.
    • Journal Title

      PLos ONE

      Volume: (in press)

    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/γcnull mouse

    • Author(s)
      Suzuki M, Takahashi T, Katano I, Ito R, Ito M, Harigae H, Ishii N, Sugamura K
    • Journal Title

      Int.Immunol.

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Journal Article] Role of Hrs in maturation of autophagosomes in mammalian cells.

    • Author(s)
      Tamai, K., Tanaka, N., Nara, A., Yamamoto, A., Nakagawa, I., Yoshimori, T., Ueno, Y., Shimose-gawa, T. and Sugamura, K
    • Journal Title

      Biochem. Biophy. Res. Comm.

    • Data Source
      KAKENHI-PROJECT-19659108
  • [Presentation] 白血病悪性化への炭酸脱水酵素CA9の関与2016

    • Author(s)
      那須 健太郎、 山口壹範、高梨友香、菅村和夫
    • Organizer
      がん支援活動 公開シンポジウム
    • Place of Presentation
      一橋大学一橋講堂(東京都、千代田区)
    • Year and Date
      2016-02-08
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] 高造腫瘍能ATL細胞における炭酸脱水酵素IX(CA9)発現亢進の意義2015

    • Author(s)
      那須健太郎、山口壹範、玉井恵一、井根省二、佐々木治、佐藤賢一、田中伸幸、張替秀郎、菅村和夫
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-07
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] 免疫不全NOGマウスを用いたヒトがん幹細胞の探索2014

    • Author(s)
      菅村和夫
    • Organizer
      第53回日本薬学会東北支部大会
    • Place of Presentation
      いわき市
    • Year and Date
      2014-10-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] 免疫不全NOGマウスを用いた高造腫瘍性ATL細胞単離法の開発2013

    • Author(s)
      山口壹範、玉井恵一、佐藤賢一、井根省二、佐々木治、田中伸幸、菅村和夫
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] Regulation of memory T cell development by OX40 costimulatory Signals2011

    • Author(s)
      Sugamura K., Ishii N.
    • Organizer
      日欧先端科学セミナー
    • Place of Presentation
      Hulshorst, Netherlands
    • Year and Date
      2011-03-03
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] HCV感染における小胞輸送タンパクHrsの役割2010

    • Author(s)
      玉井恵一、田中伸幸、上野義之、下瀬川徹、菅村和夫
    • Organizer
      第64回日本細菌学会東北地方会
    • Place of Presentation
      仙台
    • Year and Date
      2010-08-18
    • Data Source
      KAKENHI-PROJECT-21590517
  • [Presentation] Positional identification of TNFRSF14, encoding the herpes virus entry mediator, as a susceptibility gene for inflammatory bowel disease in mice2010

    • Author(s)
      Kawabe T, Irie M, Ono M, Asao A, Zhang M, Yoshida A, Takahashi T, Uede T, Watanabe N, Sugamura K, Ishii N.
    • Organizer
      国際免疫学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] OX40-Mediated Susceptibility to Leishmania major Infection is Dependent on IL-13.2010

    • Author(s)
      Asao A, Ndhlovu LC, Hoshino T, Sugamura K, Ishii N.
    • Organizer
      国際免疫学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] The analysis of the functions of human T cells in humanized NOD/shi-scid/gamma c^<null> (NOG)-HLA transgenic mice.2010

    • Author(s)
      Takahashi T, Suzuki M, Katano I, Ito R, Ishii N, Ito M, Sugamura K.
    • Organizer
      国際免疫学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] Possible regulation of hepatitis C virus secretion by Hrs-dependent exosomal pathway2010

    • Author(s)
      玉井恵一、田中伸幸、上野義之、下瀬川徹、菅村和夫
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-21590517
  • [Presentation] C-terminal region of ErbB3 controls ErbB2/ErbB3 heterodimer signaling through ubiquitin-dependent receptor degradation2010

    • Author(s)
      須賀淳子、菅村和夫、田中伸幸
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-21590517
  • [Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice)2009

    • Author(s)
      Takahashi T, Watanabe Y, Okajima A, Katano I, Ito R, Ito M, Ishii N, Tsuchiya S, Sugamura K
    • Organizer
      2nd international workshop on humanized mice
    • Place of Presentation
      オランダ・アムステルダム
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] c-Cbl dependent monoubiquitination and lysosomal degradation of gp 1302009

    • Author(s)
      田中伸幸, 菅村和夫
    • Organizer
      第68回 日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2009-10-03
    • Data Source
      KAKENHI-PROJECT-21590517
  • [Presentation] The analysis of the functions of human B and T cells in humanized NOD/shi/γcnull (NOG) mice (hu-HSC NOG mice).2009

    • Author(s)
      Takahashi T, Ito M, Sugamura K, et al
    • Organizer
      第2回ヒト化マウス国際ワークショップ
    • Place of Presentation
      オランダ
    • Data Source
      KAKENHI-PLANNED-19059001
  • [Presentation] BEX2 は静止期がん幹細胞の維持に重要な役割を果たす

    • Author(s)
      玉井恵一、中村真央、望月麻衣、小鎌直子、横山美沙、山口壹範、佐藤賢一、菅村和夫、田中伸幸
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] 下咽頭癌の浸潤におけるCD271 の役割

    • Author(s)
      望月麻衣、今井隆之、玉井恵一、山口壹範、佐藤賢一、松 浦一登、小鎌直子、横山美沙、菅村和夫、田中伸幸
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] 免疫不全NOG マウスにより分画された高造腫瘍性ATL 細胞の性状 解析

    • Author(s)
      山口壹範、那須健太郎、玉井恵一、佐藤賢一、井根省二、 佐々木治、張替秀郎、田中伸幸、菅村和夫
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25290047
  • [Presentation] ピルビン酸キナーゼM2(PKM2)は膵癌で高発現し、細胞増殖能を亢進させる

    • Author(s)
      横山美沙、白木健悠、田沼延公、玉井恵一、山口壹範、田中伸幸、菅村和夫、佐藤賢一
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25290047
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